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Funktionen

  • Privatdozent/in, Institut für Zellbiologie (Tumorforschung)

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Demuytere, Jesse; Carlier, Charlotte; Van Helden, Tom; Belza, Joke; Vanhaecke, Frank; Xie, Feifan; Vermeulen, An; Weerts, Joseph; Thomale, Jürgen; Denys, Hannelore; Tummers, Philippe; Van Kerschaver, Olivier; Willaert, Wouter; Cosyns, Sarah; Merseburger, Peter; Claeys, Arne; Van Den Eynden, Jimmy; Ceelen, Wim
    Effects of hyperthermia on cisplatin tissue penetration and gene expression in peritoneal metastases : Results from a randomized trial in ovarian cancer
    In: British Journal of Surgery (BJS) Jg. 111 (2024) Nr. 4, znae078
  • Klotz, Daniel Martin; Schwarz, Franziska Maria; Dubrovska, Anna; Schuster, Kati; Theis, Mirko; Krüger, Alexander; Kutz, Oliver; Link, Theresa; Wimberger, Pauline; Drukewitz, Stephan; Buchholz, Frank; Thomale, Jürgen; Kuhlmann, Jan Dominik
    Establishment and Molecular Characterization of an In Vitro Model for PARPi-Resistant Ovarian Cancer
    In: Cancers Jg. 15 (2023) Nr. 15, 3774
  • Frank, Daria; Patnana, Pradeep Kumar; Vorwerk, Jan; Mao, Lianghao; Gopal, Lavanya Mokada; Jung, Noelle; Hennig, Thorben; Ruhnke, Leo; Frenz, Joris Maximillian; Kuppusamy, Maithreyan; Autry, Robert; Wei, Lanying; Sun, Kaiyan; Mohammed Ahmed, Helal Mohammed; Künstner, Axel; Busch, Hauke; Müller, Heiko; Hutter, Stephan; Hoermann, Gregor; Liu, Longlong; Xie, Xiaoqing; Al-Matary, Yahya; Nimmagadda, Subbaiah Chary; Cano, Fiorella Charles; Heuser, Michael; Thol, Felicitas; Göhring, Gudrun; Steinemann, Doris; Thomale, Jürgen; Leitner, Theo; Fischer, Anja; Rad, Roland; Röllig, Christoph; Altmann, Heidi; Kunadt, Desiree; Berdel, Wolfgang E.; Hüve, Jana; Neumann, Felix; Klingauf, Jürgen; Calderon, Virginie; Opalka, Bertram; Dührsen, Ulrich; Rosenbauer, Frank; Dugas, Martin; Varghese, Julian; Reinhardt, Hans Christian; von Bubnoff, Nikolas; Möröy, Tarik; Lenz, Georg; Batcha, Aarif M. N.; Giorgi, Marianna; Selvam, Murugan; Wang, Eunice; McWeeney, Shannon K.; Tyner, Jeffrey W.; Stölzel, Friedrich; Mann, Matthias; Jayavelu, Ashok Kumar; Khandanpour, Cyrus; Mokada Gopal, Lavanya; Ahmed, Helal; Charles Cano, Fiorella
    Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy
    In: Blood Jg. 142 (2023) Nr. 25, S. 2175 - 2191
  • Hansel, Christine; Hlouschek, Julian; Xiang, Kexu; Melnikova, Margarita; Thomale, Jürgen; Helleday, Thomas; Jendrossek, Verena; Matschke, Johann
    Adaptation to chronic-cycling hypoxia renders cancer cells resistant to mth1-inhibitor treatment which can be counteracted by glutathione depletion
    In: Cells Jg. 10 (2021) Nr. 11, 3040
  • Ewers, Katharina M.; Patil, Shilpa; Kopp, Waltraut; Thomale, Jürgen; Quilitz, Tabea; Magerhans, Anna; Wang, Xin; Hessmann, Elisabeth; Dobbelstein, Matthias
    HSP90 Inhibition Synergizes with Cisplatin to Eliminate Basal-like Pancreatic Ductal Adenocarcinoma Cells
    In: Cancers Jg. 13 (2021) Nr. 24, 6163
  • Heinze, Karolin; Hölzer, Martin; Ungelenk, Martin; Gerth, Melanie; Thomale, Jürgen; Heller, Regine; Morden, Claire R.; McManus, Kirk J.; Mosig, Alexander S.; Dürst, Matthias; Runnebaum, Ingo B.; Häfner, Norman
    RUNX3 transcript variants have distinct roles in ovarian carcinoma and differently influence platinum sensitivity and angiogenesis
    In: Cancers Jg. 13 (2021) Nr. 3, S. 476
  • Böckelmann, Lukas; Starzonek, Christin; Niehoff, Ann-Christin; Karst, Uwe; Thomale, Jürgen; Schlüter, Hartmut; Bokemeyer, Carsten; Aigner, Achim; Schumacher, Udo
    Detection of doxorubicin, cisplatin and therapeutic antibodies in formalin-fixed paraffin-embedded human cancer cells
    In: Histochemistry and Cell Biology Jg. 153 (2020) Nr. 5, S. 367 - 377
  • Melnikova, Margarita; Wauer, Ulrike Sophie; Mendus, Diana; Hilger, Ralf Axel; Oliver, Trudy G.; Mercer, Kim; Gohlke, Björn Oliver; Erdmann, Kati; Niederacher, Dieter; Neubauer, Hans; Buderath, Paul; Wimberger, Pauline; Kuhlmann, Jan Dominik; Thomale, Jürgen
    Diphenhydramine increases the therapeutic window for platinum drugs by simultaneously sensitizing tumor cells and protecting normal cells
    In: Molecular Oncology Jg. 14 (2020) Nr. 4, S. 686 - 703
  • Seoane, Marcos; Buhs, Sophia; Iglesias, Pablo; Strauss, Julia; Puller, Ann-Christin; Müller, Jürgen; Gerull, Helwe; Feldhaus, Susanne; Alawi, Malik; Brandner, Johanna M.; Eggert, Dennis; Du, Jinyan; Thomale, Jürgen; Wild, Peter J.; Zimmermann, Martin; Sternsdorf, Thomas; Schumacher, Udo; Nollau, Peter; Fisher, David E.; Horstmann, Martin A.
    Lineage-specific control of TFIIH by MITF determines transcriptional homeostasis and DNA repair
    In: Oncogene Jg. 38 (2019) Nr. 19, S. 3616 - 3635
  • Riaz, Muhammad Assad; Sak, Ali; Erol, Yasin Bahadir; Groneberg, Michael; Thomale, Jürgen; Stuschke, Martin
    Metformin enhances the radiosensitizing effect of cisplatin in non-small cell lung cancer cell lines with different cisplatin sensitivities
    In: Scientific Reports Jg. 9 (2019) S. 1282
  • Riaz, A.; Sak, Ali; Erol, Y. B.; Groneberg, M.; Melnikova, M.; Thomale, Jürgen; Stuschke, Martin
    Combined effects of metformin and cisplatin on radiation sensitivity in non-small cell lung cancer cells
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 194 (2018) Nr. Suppl.1, S. 100
  • Skowron, Margaretha A.; Melnikova, Margarita; Van Roermund, Joep G. H.; Romano, Andrea; Albers, Peter; Thomale, Jürgen; Schulz, Wolfgang A.; Niegisch, Günter; Hoffmann, Michèle J.
    Multifaceted mechanisms of cisplatin resistance in long-term treated urothelial carcinoma cell lines
    In: International Journal of Molecular Sciences (IJMS) Jg. 19 (2018) Nr. 2, S. 590
  • Leo, Markus; Schmitt, Linda-Isabell; Jastrow, Holger; Thomale, Jürgen; Kleinschnitz, Christoph; Hagenacker, Tim
    Cisplatin alters the function and expression of N-type voltage-gated calcium channels in the absence of morphological damage of sensory neurons.
    In: Molecular Pain Jg. 13 (2017) 1744806917746565
  • Leo, Markus; Schmitt, Linda-Isabell; Erkel, Martin; Melnikova, Margarita; Thomale, Jürgen; Hagenacker, Tim
    Cisplatin-induced neuropathic pain is mediated by upregulation of N-type voltage-gated calcium channels in dorsal root ganglion neurons
    In: Experimental Neurology Jg. 288 (2017) S. 62 - 74
  • Ruhe, Lena; Ickert, Stefanie; Hochkirch, Ulrike; Hofmann, Johanna; Beck, Sebastian; Thomale, Jürgen; Linscheid, Michael W.
    Comprehensive Molecular Characterization of a Cisplatin-Specific Monoclonal Antibody
    In: Molecular Pharmaceutics Jg. 14 (2017) Nr. 12, S. 4454 - 4461
  • Sánchez-González, Penélope D.; López-Hernández, Francisco J.; Dueñas, Montserrat; Prieto, Marta; Sánchez-López, Elsa; Thomale, Jürgen; Ruiz-Ortega, Marta; López-Novoa, José M.; Morales, Ana I.
    Differential effect of quercetin on cisplatin-induced toxicity in kidney and tumor tissues
    In: Food and Chemical Toxicology Jg. 107 (2017) S. 226 - 236
  • Riaz, A. M.; Sak, Ali; Erol, B. Y.; Groneberg, M.; Melnikova, M.; Thomale, Jürgen; Stuschke, Martin
    Metformin potentiates radiosensitizing effect of cisplatin in NSCLC cells
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 193 (2017) Nr. Suppl.1, S. 27
  • Mary Photini, Stella; Dürst, Matthias; Jansen, Lars; Steinbach, Daniel; Gajda, Mieczyslaw; Sonnemann, Jürgen; Hoffmann, Franziska; Thomale, Jürgen; Runnebaum, Ingo B.; Mosig, Alexander S.; Melnikova, Margarita; Häfner, Norman; Peters, Sven; Kritsch, Daniel
    Tribbles 2 mediates cisplatin sensitivity and DNA damage response in epithelial ovarian cancer
    In: International Journal of Cancer Jg. 141 (2017) Nr. 8, S. 1600 - 1614
  • Melnikova, Margarita; Thomale, Jürgen
    Visualization and Quantitative Measurement of Drug-Induced Platinum Adducts in the Nuclear DNA of Individual Cells by an Immuno-Cytological Assay
    In: Methods in Molecular Biology (2017) S. 351 - 358
  • Hampp, Stephanie; Kiessling, Tina; Buechle, Kerstin; Mansilla, Sabrina F; Thomale, Jürgen; Rall, Melanie; Ahn, Jinwoo; Pospiech, Helmut; Gottifredi, Vanesa; Wiesmüller, Lisa
    DNA damage tolerance pathway involving DNA polymerase ? and the tumor suppressor p53 regulates DNA replication fork progression
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 113 (2016) Nr. 30, S. E4311 - 9
  • Jokić, Mladen; Vlašić, Ignacija; Rinneburger, Miriam; Klümper, Niklas; Spiro, Judith; Vogel, Wenzel; Offermann, Anne; Kümpers, Christiane; Fritz, Christian; Schmitt, Anna; Riabinska, Arina; Wittersheim, Maike; Michels, Sebastian; Ozretić, Luka; Florin, Alexandra; Welcker, Daniela; Akyuz, Mehmet Deniz; Nowak, Michael; Erkel, Martin; Wolf, Jürgen; Büttner, Reinhard; Schumacher, Björn; Thomale, Jürgen; Persigehl, Thorsten; Maintz, David; Perner, Sven; Reinhardt, Hans Christian
    Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner
    In: Molecular Cancer Research Jg. 14 (2016) Nr. 11, S. 1110 - 1123
  • Krüger, Katharina; Ziegler, Verena; Hartmann, Christina; Henninger, Christian; Thomale, Jürgen; Schupp, Nicole; Fritz, Gerhard
    Lovastatin prevents cisplatin-induced activation of pro-apoptotic DNA damage response (DDR) of renal tubular epithelial cells
    In: Toxicology and Applied Pharmacology Jg. 292 (2016) S. 103 - 114
  • Bretz, Anne Catherine; Gittler, Miriam P; Charles, Joël P; Gremke, Niklas; Eckhardt, Ines; Mernberger, Marco; Mandic, Robert; Thomale, Jürgen; Nist, Andrea; Wanzel, Michael; Stiewe, Thorsten
    ΔNp63 activates the Fanconi anemia DNA repair pathway and limits the efficacy of cisplatin treatment in squamous cell carcinoma
    In: Nucleic Acids Research Jg. 44 (2016) Nr. 7, S. 3204 - 3218
  • Paul-Konietzko, Katja; Thomale, Jürgen; Arakawa, Hiroshi; Iliakis, George
    DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar Efficiency
    In: Photochemistry and Photobiology Jg. 91 (2015) Nr. 5, S. 1173 - 1180
  • Zivanovic, Oliver; Abramian, Alina; Kullmann, Maximilian; Fuhrmann, Christine; Coch, Christoph; Hoeller, Tobias; Ruehs, Hauke; Keyver-Paik, Mignon Denise; Rudlowski, Christian; Weber, Stefan; Kiefer, Nicholas; Poelcher, Martin L.; Thiesler, Thore; Rostamzadeh, Babak; Mallmann, Michael; Schaefer, Nico; Permantier, Maryse; Latten, Sandra; Kalff, Joerg; Thomale, Jürgen; Jaehde, Ulrich; Kuhn, Walter C.
    HIPEC ROC I : A phase i study of cisplatin administered as hyperthermic intraoperative intraperitoneal chemoperfusion followed by postoperative intravenous platinum-based chemotherapy in patients with platinum-sensitive recurrent epithelial ovarian cancer
    In: International Journal of Cancer Jg. 136 (2015) Nr. 3, S. 699 - 708
  • Krüger, Katharina; Thomale, Jürgen; Stojanović, Nikolina; Osmak, Maja; Henninger, Christian; Bormann, Stefanie; Fritz, Gerhard
    Platinum-induced kidney damage : Unraveling the DNA damage response (DDR) of renal tubular epithelial and glomerular endothelial cells following platinum injury
    In: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Jg. 1853 (2015) Nr. 3, S. 685 - 698
  • Keitel, Ulrike; Scheel, Andreas; Thomale, Jürgen; Halpape, Rovena; Kaulfuß, Silke; Scheel, Christina; Dobbelstein, Matthias
    Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation
    In: OncoTarget Jg. 5 (2014) Nr. 23, S. 11778 - 11791
  • Barr, M. P.; Rausch, R.; Thomale, Jürgen; Richard, D.; Cuffe, S.; Finn, S.; O'Byrne, K. J.
    Inhibition of PARP activity by PJ34 sensitises NSCLC cells to cisplatin
    In: Lung Cancer Jg. 83 (2014) Nr. Suppl. 1, S. 2
  • Raluy, Laia Pagerols; Nollau, Peter; Brandner, Johanna M.; Wild, Peter J.; Zimmermann, Martin; Schumacher, Udo; Kaufmann, Karoline; Horstmann, Martin A.; Strauss, Julia; Thomale, Jürgen; Dierck, Kevin; Fisher, David E.; Seoane, Marcos; Du, Jinyan
    Regulation of the functional interface between nucleotide excision repair and transcription by MITF modulates melanoma growth
    In: Cancer Research Jg. 74 (2014) Nr. 19 Suppl., S. 2950
  • Houthuijzen, JuliaM; Daenen, LauraGM; Roodhart, JeanineML; Govaert, KlaasM; Smith, MichelleE; Thomale, Jürgen; Sadatmand, SaharJ; Rosing, Hilde; Kruse, Fabian; van Rooijen, Nico; Beijnen, JosH; Borst, Piet; Rottenberg, Sven; Haribabu, Bodduluri; Voest, EmileE
    Splenic macrophages induce chemotherapy resistance via DNA damage repair
    In: Cancer Research Jg. 74 (2014) Nr. Suppl. 19, S. 3771
  • Funk, Florian; Krüger, Katharina; Henninger, Christian; Wätjen, Wim; Proksch, Peter; Thomale, Jürgen; Fritz, Gerhard
    Spongean alkaloids protect rat kidney cells against cisplatin-induced cytotoxicity
    In: Anti-Cancer Drugs Jg. 25 (2014) Nr. 8, S. 917 - 929
  • Barr, M. P.; Gray, S. G.; Fennell, D. A.; O'Leary, J. J.; Richard, D.; Thomale, Jürgen; Hoffmann, Andreas-Claudius; O'Byrne, K. J.
    2 MicroRNA profiling and cisplatin–DNA interactions in an isogenic model of cisplatin resistant NSCLC cell lines
    In: Lung Cancer Jg. 79 (2013) Nr. Suppl. 1, S. 1
  • Krueger, K.; Fritz, G.; Thomale, Jürgen
    Comparative analysis of the sensitivity of normal rat kidney cells towards different types of platinum compounds
    In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 386 (2013) Nr. Suppl. 1, S. 45
  • Friboulet, Luc; Olaussen, Ken André; Pignon, Jean-Pierre; Shepherd, Frances A.; Tsao, Ming-Sound; Graziano, Stephen; Kratzke, Robert; Douillard, Jean-Yves; Seymour, Lesley; Pirker, Robert; Filipits, Martin; André, Fabrice; Solary, Eric; Ponsonnailles, Florence; Robin, Angélique; Stoclin, Annabelle; Dorvault, Nicolas; Commo, Frédéric; Adam, Julien; Vanhecke, Elsa; Saulnier, Patrick; Thomale, Jürgen; Le Chevalier, Thierry; Dunant, Ariane; Rousseau, Vanessa; Le Teuff, Gwénaël; Brambilla, Elisabeth; Soria, Jean-Charles
    ERCC1 isoform expression and DNA repair in non-small-cell lung cancer
    In: The New England Journal of Medicine Jg. 368 (2013) Nr. 12, S. 1101 - 1110
  • Eicher, Carmen; Dewerth, Alexander; Thomale, Jürgen; Ellerkamp, Verena; Hildenbrand, Sibylle L.; Warmann, Steven W.; Fuchs, Jörg; Armeanu-Ebinger, Sorin
    Effect of sorafenib combined with cytostatic agents on hepatoblastoma cell lines and xenografts
    In: British Journal of Cancer (BJC) Jg. 108 (2013) Nr. 2, S. 334 - 341
  • Berulava, Tea; Ziehe, Matthias; Klein-Hitpaß, Ludger; Mladenov, Emil; Thomale, Jürgen; Rüther, Ulrich; Horsthemke, Bernhard
    FTO levels affect RNA modification and the transcriptome
    In: European Journal of Human Genetics Jg. 21 (2013) Nr. 3, S. 317 - 323
  • Nel, I.; Gauler, Thomas; Eberhardt, Wilfried; Nickel, A. C.; Schuler, Martin; Thomale, Jürgen; Hoffmann, Andreas-Claudius
    Formation and repair kinetics of Pt-(GpG) DNA adducts in extracted circulating tumour cells and response to platinum treatment
    In: British Journal of Cancer (BJC) Jg. 109 (2013) Nr. 5, S. 1223 - 1229
  • Barr, Martin P.; Gray, Steven G.; Hoffmann, Andreas-Claudius; Hilger, Ralf A.; Thomale, Jürgen; O'Flaherty, John D.; Fennell, Dean A.; Richard, Derek; O'Leary, John J.; O'Byrne, Kenneth J.
    Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature
    In: PLoS ONE Jg. 8 (2013) Nr. 1, S. e54193
  • Olaussen, Ken A.; Adam, Julien; Vanhecke, Elsa; Vielh, Philippe; Pirker, Robert; Friboulet, Luc; Popper, Helmut; Robin, Angélique; Commo, Fréderic; Thomale, Jürgen; Kayitalire, Louis; Filipits, Martin; Le Chevalier, Thierry; André, Fabrice; Brambilla, Elisabeth; Soria, Jean-Charles
    PARP1 impact on DNA repair of platinum adducts: Preclinical and clinical read-outs
    In: Lung Cancer Jg. 80 (2013) Nr. 2, S. 216 - 222
  • Rausch, Raya; Barr, MartinP; Thomale, Jürgen; Richard, Derek; OByrne, Kenneth
    Parb inhibition increases sensitivity of NSCLC cells to cisplatin
    In: Journal of Thoracic Oncology Jg. 8 (2013) Nr. Suppl. 2, S. 470
  • Nell, I.; Gauler, Thomas; Nickel, A. C.; Alotaibi, S.; Thomale, Jürgen; Schuler, Martin; Hoffmann, Andreas-Claudius
    Pre-therapeutic ex-vivo repair kinetics of cisplatin-DNA-adducts in circulating tumor cells (CTC) as platinum resistance test
    In: Lung Cancer Jg. 79 (2013) Nr. Suppl. 1, S. 2
  • Fenske, Annabelle E.; Glaesener, Stephanie; Bokemeyer, Carsten; Thomale, Jürgen; Dahm-Daphi, Jochen; Honecker, Friedemann; Dartsch, Dorothee C.
    Cisplatin resistance induced in germ cell tumour cells is due to reduced susceptibility towards cell death but not to altered DNA damage induction or repair
    In: Cancer Letters Jg. 324 (2012) Nr. 2, S. 171 - 178
  • Thomale, Jürgen
    Efficient pharmacological prevention of the major side effects of cisplatin without affecting the antineoplastic effiacy in vivo
    In: Annals of Oncology Jg. 23 (2012) Nr. Suppl. 1, S. 25
  • Barr, M.; Gray, S. G.; Fennell, D. A.; O'Leary, J. J.; Richard, D.; Thomale, Jürgen; Hoffmann, Andreas-Claudius; O'Byrne, K. J.
    Microrna profiling and CDDP-GPG dna adduct formation analysis in a panel of cisplatin resistant non-small cell lung cancer cell lines
    In: Annals of Oncology Jg. 23 (2012) Nr. Suppl. 9, S. 68
  • Ziehe, Matthias; Esteban-Fernández, Diego; Hochkirch, Ulrike; Thomale, Jürgen; Linscheid, Michael W.
    On the complexity and dynamics of in vivo Cisplatin-DNA adduct formation using HPLC/ICP-MS
    In: Metallomics Jg. 4 (2012) Nr. 10, S. 1098 - 1104
  • Galluzzi, Lorenzo; Vitale, Ilio; Senovilla, Laura; Olaussen, Ken André; Pinna, Guillaume; Eisenberg, Tobias; Goubar, Aïcha; Martins, Isabelle; Michels, Judith; Kratassiouk, Gueorgui; Carmona-Gutierrez, Didac; Scoazec, Marie; Vacchelli, Erika; Schlemmer, Frederic; Kepp, Oliver; Shen, Shensi; Tailler, Maximilien; Niso-Santano, Mireia; Morselli, Eugenia; Criollo, Alfredo; Adjemian, Sandy; Jemaà, Mohamed; Chaba, Kariman; Pailleret, Claire; Michaud, Mickaël; Pietrocola, Federico; Tajeddine, Nicolas; de La Motte Rouge, Thibault; Araujo, Natalia; Morozova, Nadya; Robert, Thomas; Ripoche, Hugues; Commo, Frederic; Besse, Benjamin; Validire, Pierre; Fouret, Pierre; Robin, Angélique; Dorvault, Nicolas; Girard, Philippe; Gouy, Sébastien; Pautier, Patricia; Jägemann, Nora; Nickel, Ann-Christin; Marsili, Sabrina; Paccard, Caroline; Servant, Nicolas; Hupé, Philippe; Behrens, Carmen; Behnam-Motlagh, Parviz; Kohno, Kimitoshi; Cremer, Isabelle; Damotte, Diane; Alifano, Marco; Midttun, Øivind; Ueland, Per Magne; Lazar, Vladimir; Dessen, Philippe; Zischka, Hans; Chatelut, Etienne; Castedo, Maria; Madeo, Frank; Barillot, Emmanuel; Thomale, Jürgen; Wistuba, Ignacio Ivan; Sautès-Fridman, Catherine; Zitvogel, Laurence; Soria, Jean-Charles; Harel-Bellan, Annick; Kroemer, Guido; Olaussen, Ken André; de La Motte Rouge, Thibault; Ueland, Per Magne; Wistuba, Ignacio Ivan
    Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer
    In: Cell Reports Jg. 2 (2012) Nr. 2, S. 257 - 269
  • Mowaka, Shereen; Ziehe, Matthias; Mohamed, Dalia; Hochkirch, Ulrike; Thomale, Jürgen; Linscheid, Michael W.
    Structures of oxaliplatin-oligonucleotide adducts from DNA
    In: Journal of Mass Spectrometry Jg. 47 (2012) Nr. 10, S. 1282 - 1293
  • Boeckmann, L.; Nickel, A-C; Kuschal, C.; Schaefer, A.; Thoms, K-M; Schoen, M. P.; Thomale, Jürgen; Emmert, S.
    Differential Melanoma-Chemoresistence to Temozolomide within varying Treatment Schemes : DNA-Damage-Accumulation as Determinants
    In: Journal der Deutschen Dermatologischen Gesellschaft (JDDG) Jg. 9 (2011) Nr. 9, S. 791 - 791
  • Wang, Qi-En; Milum, Keisha; Han, Chunhua; Huang, Yi-Wen; Wani, Gulzar; Thomale, Jürgen; Wani, Altaf A.
    Differential contributory roles of nucleotide excision and homologous recombination repair for enhancing cisplatin sensitivity in human ovarian cancer cells
    In: Molecular Cancer (2011) 24
  • Boeckmann, Lars; Nickel, Ann-Christin; Kuschal, Christiane; Schaefer, Annika; Thoms, Kai-Martin; Schön, Michael P; Thomale, Jürgen; Emmert, Steffen
    Temozolomide chemoresistance heterogeneity in melanoma with different treatment regimens : DNA damage accumulation contribution
    In: Melanoma Research Jg. 21 (2011) Nr. 3, S. 206 - 216
  • Gutekunst, Matthias; Oren, Moshe; Weilbacher, Andrea; Dengler, Michael A.; Markwardt, Christiane; Thomale, Jürgen; Aulitzky, Walter E.; van der Kuip, Heiko
    p53 Hypersensitivity Is the Predominant Mechanism of the Unique Responsiveness of Testicular Germ Cell Tumor (TGCT) Cells to Cisplatin
    In: PLoS ONE Jg. 6 (2011) Nr. 4,
  • Oliver, Trudy G.; Mercer, Kim L.; Sayles, Leanne C.; Burke, James R.; Mendus, Diana; Lovejoy, Katherine S.; Cheng, Mei-Hsin; Subramanian, Aravind; Mu, David; Powers, Scott; Crowley, Denise; Bronson, Roderick T.; Whittaker, Charles A.; Bhutkar, Arjun; Lippard, Stephen J.; Golub, Todd; Thomale, Jürgen; Jacks, Tyler; Sweet-Cordero, E. Alejandro
    Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer
    In: Genes and Development Jg. 24 (2010) Nr. 8, S. 837 - 852
  • Usanova, Svetlana; Piée-Staffa, Andrea; Sied, Ulrike; Thomale, Jürgen; Schneider, Astrid; Kaina, Bernd; Köberle, Beate
    Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression
    In: Molecular Cancer Jg. 9 (2010) 248
  • Geis, Christian; Graulich, M.; Wissmann, Andreas; Hagenacker, Tim; Thomale, Jürgen; Sommer, Claudia L.; Schäfers, Maria
    Evoked pain behavior and spinal glia activation is dependent on tumor necrosis factor receptor 1 and 2 in a mouse model of bone cancer pain
    In: Neuroscience Jg. 169 (2010) Nr. 1, S. 463 - 474
  • Yoon, Min-Suk; Bechmann, Lars Peter; Obermann, Mark; Yepnjouo, Olivia; Egensperger, Rupert; Gerken, Guido; Katsarava, Zaza; Thomale, Jürgen; Holtmann, Gerald
    Recombinant human erythropoietin counteracts cisplatin-induced visceral hyperalgesia
    In: Neuroscience Bulletin Jg. 26 (2010) Nr. 4, S. 282 - 288
  • Aleksunes, Lauren M.; Goedken, Michael J.; Rockwell, Cheryl E.; Thomale, Jürgen; Manautou, Jose E.; Klaassen, Curtis D.
    Transcriptional regulation of renal cytoprotective genes by Nrf2 and its potential use as a therapeutic target to mitigate cisplatin-induced nephrotoxicity
    In: The Journal of Pharmacology and Experimental Therapeutics Jg. 335 (2010) Nr. 1, S. 2 - 12
  • Eisele, Lewin; Prinz, Robert; Klein-Hitpaß, Ludger; Nückel, Holger; Lowinksi, Kerstin; Thomale, Jürgen; Möller, Lars; Dührsen, Ulrich; Dürig, Jan
    Combined PER2 and CRY1 expression predicts outcome in chronic lymphocytic leukemia
    In: European Journal of Haematology Jg. 83 (2009) Nr. 4, S. 320 - 327
  • Yoon, Min-Suk; Katsarava, Zaza; Obermann, Mark; Schäfers, Maria; Liedert, Bernd; Dzagnidze, Anna; Kribben, Andreas; Egensperger, Rupert; Limmroth, Volker; Diener, Hans Christoph; Thomale, Jürgen
    Erythropoietin overrides the triggering effect of DNA platination products in a mouse model of Cisplatin-induced neuropathy
    In: BMC Neuroscience Jg. 10 (2009)
  • Hüttmann, Andreas; Klein-Hitpaß, Ludger; Thomale, Jürgen; Deenen, R.; Nückel, Holger; Ebeling, Peter; Führer, A.; Edelmann, J.; Sellmann, Ludger; Dührsen, Ulrich; Dürig, Jan
    Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression status
    In: Leukemia Jg. 20 (2006) Nr. 10, S. 1774 - 1782
  • Abstracts

  • Qiu, Ye; Mladenov, Emil; Thomale, Jürgen; Sak, Ali; Stuschke, Martin; Iliakis, George
    Cell cycle specific analysis of cisplatin-radiation interactions : Focus on DNA double strand break induction and processing
    In: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 199 (2023)
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