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Dr. rer. nat. Alexandra Gellhaus

Funktionen

  • ---, Institut für Molekularbiologie (Tumorforschung)

  • Mitglied/er, Institut für Anatomie

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Duan, Liyan; Ma, Yuyang; Reisch, Beatrix; Hadrovic, Elina; Mach, Pawel; Kimmig, Rainer; Jahn, Michael; Köninger, Angela; Iannaccone, Antonella; Gellhaus, Alexandra
    Alteration in sB7-H4 Serum Levels and Placental Biomarker Expression after Therapeutic Plasma Exchange in Early-Onset Preeclampsia Patients
    In: International Journal of Molecular Sciences (IJMS) , Jg. 25 2024, Nr. 20, 11082
    DOI (Open Access)
  • Ma, Yuyang; Duan, Liyan; Reisch, Beatrix; Kimmig, Rainer; Iannaccone, Antonella; Gellhaus, Alexandra
    CCN1-Mediated Signaling in Placental Villous Tissues after SARS-CoV-2 Infection in Term Pregnant Women : Implications for Dysregulated Angiogenesis
    In: Current Issues in Molecular Biology , Jg. 46 2024, Nr. 4, S. 3533 – 3550
    DOI, Online Volltext (Open Access)
  • Nagel, Laura E.; Reisch, Beatrix; Schwenk, Udo; Kimmig, Rainer; Darkwah Oppong, Marvin; Dzietko, Mark; Gellhaus, Alexandra; Iannaccone, Antonella
    Impact of 2 years of COVID-19 pandemic on preterm birth : Experience from a tertiary center of obstetrics in western Germany
    In: International Journal of Gynecology & Obstetrics , Jg. 166 2024, Nr. 1, S. 404 – 411
    DOI (Open Access)
  • Ma, Yuyang; Duan, Liyan; Reisch, Beatrix; Kimmig, Rainer; Iannaccone, Antonella; Gellhaus, Alexandra
    Impact of the Immunomodulatory Factor Soluble B7-H4 in the Progress of Preeclampsia by Inhibiting Essential Functions of Extravillous Trophoblast Cells
    In: Cells , Jg. 13 2024, Nr. 16, 1372
    DOI, Online Volltext (Open Access)
  • Vogtmann, Rebekka; Riedel, Alina; Sassmannshausen, Ivanka; Langer, Sarah; Kühnel-Terjung, Elisabeth; Kimmig, Rainer; Schorle, Hubert; Winterhager, Elke; Gellhaus, Alexandra
    Overexpression of Human sFLT1 in the Spongiotrophoblast Is Sufficient to Induce Placental Dysfunction and Fetal Growth Restriction in Transgenic Mice
    In: International Journal of Molecular Sciences (IJMS) , Jg. 25 2024, Nr. 4, 2040
    DOI, Online Volltext (Open Access)
  • Kirkgöz, Kürsat; Vogtmann, Rebekka; Xie, Yiran; Zhao, Fangqi; Riedel, Alina; Adam, Lisa-Marie; Freitag, Nancy; Harms, Charlotte; Garcia, Mariana G.; Plösch, Torsten; Gellhaus, Alexandra; Blois, Sandra M.
    Placental glycosylation senses the anti-angiogenic milieu induced by human sFLT1 during pregnancy
    In: Journal of Reproductive Immunology , Jg. 164 2024, 104284
    DOI (Open Access)
  • Phan, Julia; Chen, Brandon; Zhao, Zhiyu; Allies, Gabriele; Iannaccone, Antonella; Paul, Animesh; Cansiz, Feyza; Spina, Alberto; Leven, Anna-Sophia; Gellhaus, Alexandra; Schadendorf, Dirk; Kimmig, Rainer; Mettlen, Marcel; Tasdogan, Alpaslan; Morrison, Sean J.
    Retrotransposons are co-opted to activate hematopoietic stem cells and erythropoiesis
    In: Science , Jg. 386 2024, Nr. 6722, eado6836
    DOI
  • Iannaccone, Antonella; Gellhaus, Alexandra; Reisch, Beatrix; Dzietko, Mark; Schmidt, Börge; Mavarani, Laven; Kraft, Katrina; Andresen, Kristin; Kimmig, Rainer; Pecks, Ulrich; Schleußner, Ekkehard
    The Importance of Vaccination, Variants and Time Point of SARS-CoV-2 Infection in Pregnancy for Stillbirth and Preterm Birth Risk : An Analysis of the CRONOS Register Study
    In: Journal of Clinical Medicine (JCM) , Jg. 13 2024, Nr. 6, 1522
    DOI (Open Access)
  • El-Shorafa, HM; Müller, MM; Schmidt, A; Duan, L; Groten, T; Gellhaus, Alexandra; Markert, UR; Favaro, RR
    4miR-193b-3p localization, transport and functions
    In: Journal of Reproductive Immunology , Jg. 158 2023, 103587
    DOI
  • Vogtmann, Rebekka; Bao, Mian; Dewan, Monia Vanessa; Riedel, Alina; Kimmig, Rainer; Felderhoff-Müser, Ursula; Bendix, Ivo; Plösch, Torsten; Gellhaus, Alexandra
    Growth-Restricted Fetuses and Offspring Reveal Adverse Sex-Specific Metabolic Responses in Preeclamptic Mice Expressing Human sFLT1
    In: International Journal of Molecular Sciences (IJMS) , Jg. 24 2023, Nr. 8, 6885
    DOI, Online Volltext (Open Access)
  • Pires, Ana Salomé; Bollini, Sveva; Botelho, Maria Filomena; Lang-Olip, Ingrid; Ponsaerts, Peter; Balbi, Carolina; Lange-Consiglio, Anna; Fénelon, Mathilde; Mojsilović, Slavko; Berishvili, Ekaterine; Cremonesi, Fausto; Gazouli, Maria; Bugarski, Diana; Gellhaus, Alexandra; Kerdjoudj, Halima; Schoeberlein, Andreina
    Guidelines to Analyze Preclinical Studies Using Perinatal Derivatives
    In: Methods and Protocols , Jg. 6 2023, Nr. 3, 45
    DOI (Open Access)
  • Murrieta-Coxca, José M.; Barth, Emanuel; Fuentes-Zacarias, Paulina; Gutiérrez-Samudio, Ruby N.; Groten, Tanja; Gellhaus, Alexandra; Köninger, Angela; Marz, Manja; Markert, Udo R.; Morales-Prieto, Diana M.
    Identification of altered miRNAs and their targets in placenta accreta
    In: Frontiers in Endocrinology , Jg. 14 2023, 1021640
    DOI (Open Access)
  • Kirkgöz, Kürsat; Adam, Lisa-Marie; Vogtmann, Rebekka; Riedel, Alina; Zhao, Fangqi; Xie, Yiran; Gellhaus, Alexandra; Blois, Sandra M.
    Overexpression of maternal sFlt1 (Soluble fms-Like Tyrosine Kinase-1) induces dysregulation of galectin-1 at the maternal-fetal interface
    In: Journal of Reproductive Immunology , Jg. 159 2023, S. 104094
    DOI
  • Iannaccone, Antonella; Reisch, Beatrix; Kimmig, Rainer; Schmidt, Börge; Mavarani, Laven; Darkwah Oppong, Marvin; Tyczynski, Bartosz; Dzietko, Mark; Jahn, Michael; Gellhaus, Alexandra; Köninger, Angela
    Therapeutic Plasma Exchange in Early-Onset Preeclampsia : A 7-Year Monocentric Experience
    In: Journal of Clinical Medicine (JCM) , Jg. 12 2023, Nr. 13, 4289
    DOI (Open Access)
  • Freise, Lennart; Behncke, Rose Yinghan; Allerkamp, Hanna Helene; Sandermann, Tim Henrik; Chu, Ngoc Hai; Funk, Eva Maria; Hondrich, Lukas Jonathan; Riedel, Alina; Witzel, Christian; Hansmeier, Nils Rouven; Danyel, Magdalena; Gellhaus, Alexandra; Dechend, Ralf; Hägerling, René
    Three-Dimensional Histological Characterization of the Placental Vasculature Using Light Sheet Microscopy
    In: Biomolecules , Jg. 13 2023, Nr. 6, 1009
    DOI (Open Access)
  • Andrikos, Argyrios; Andrikos, Dimitrios; Schmidt, Börge; Birdir, Cahit; Kimmig, Rainer; Gellhaus, Alexandra; Köninger, Angela
    Course of the sFlt-1/PlGF ratio in fetal growth restriction and correlation with biometric measurements, feto-maternal Doppler parameters and time to delivery
    In: Archives of Gynecology and Obstetrics , Jg. 305 2022, Nr. 3, S. 597 – 605
    DOI (Open Access)
  • Schmitz, Katrin; Turnwald, Eva-Maria; Kretschmer, Tobias; Janoschek, Ruth; Bae-Gartz, Inga; Voßbrecher, Kathrin; Kammerer, Merlin D.; Köninger, Angela; Gellhaus, Alexandra; Handwerk, Marion; Wohlfarth, Maria; Gründemann, Dirk; Hucklenbruch-Rother, Eva; Dötsch, Jörg; Appel, Sarah
    Metformin Prevents Key Mechanisms of Obesity-Related Complications in Visceral White Adipose Tissue of Obese Pregnant Mice
    In: Nutrients , Jg. 14 2022, Nr. 11, 2288
    DOI (Open Access)
  • Mach, Pawel; Köninger, Angela; Reisch, Beatrix; Kimmig, Rainer; Gellhaus, Alexandra
    Soluble PD-L1 and B7-H4 serum levels during the course of physiological pregnancy
    In: American Journal of Reproductive Immunology , Jg. 87 2022, Nr. 3, e13519
    DOI (Open Access)
  • Iannaccone, A.; Reisch, B.; Mavarani, L.; Darkwah Oppong, M.; Kimmig, R.; Mach, P.; Schmidt, B.; Köeninger, A.; Gellhaus, A.
    Soluble endoglin versus sFlt-1/PlGF ratio : Detection of preeclampsia, HELLP syndrome, and FGR in a high-risk cohort
    In: Hypertension in Pregnancy , Jg. 41 2022, Nr. 3-4, S. 159 – 172
    DOI
  • Vogtmann, Rebekka; Burk, Lilo Valerie; Serdar, Meray; Kimmig, Rainer; Bendix, Ivo; Gellhaus, Alexandra
    Systemic Maternal Human sFLT1 Overexpression Leads to an Impaired Foetal Brain Development of Growth-Restricted Foetuses upon Experimental Preeclampsia
    In: Oxidative Medicine and Cellular Longevity , Jg. 2022 2022, 3024032
    DOI, Online Volltext (Open Access)
  • Middendorf, Lisa; Gellhaus, Alexandra; Iannaccone, Antonella; Köninger, Angela; Dathe, Anne-Kathrin; Bendix, Ivo; Reisch, Beatrix; Felderhoff-Müser, Ursula; Hüning, Britta Maria
    The Impact of Increased Maternal sFlt-1/PlGF Ratio on Motor Outcome of Preterm Infants
    In: Frontiers in Endocrinology , Jg. 13 2022, 913514
    DOI, Online Volltext (Open Access)
  • Duan, Liyan; Reisch, Beatrix; Mach, Pawel; Kimmig, Rainer; Gellhaus, Alexandra; Iannaccone, Antonella
    The immunological role of B7-H4 in pregnant women with Sars-Cov2 infection
    In: American Journal of Reproductive Immunology , Jg. 88 2022, Nr. 6, e13626
    DOI (Open Access)
  • Duan, Liyan; Reisch, Beatrix; Iannaccone, Antonella; Hadrovic, Elina; Wu, Yuqing; Vogtmann, Rebekka; Winterhager, Elke; Kimmig, Rainer; Köninger, Angela; Mach, Pawel; Gellhaus, Alexandra
    Abnormal expression of the costimulatory molecule B7‐H4 in placental chorionic villous and decidual basalis tissues of patients with preeclampsia and HELLP syndrome
    In: American Journal of Reproductive Immunology , Jg. 86 2021, Nr. 3, e13430
    DOI (Open Access)
  • Vogtmann, Rebekka; Heupel, Jacqueline; Herse, Florian; Matin, Mahsa; Hagmann, Henning; Bendix, Ivo; Kräker, Kristin; Dechend, Ralf; Winterhager, Elke; Kimmig, Rainer; Köninger, Angela; Gellhaus, Alexandra
    Circulating Maternal sFLT1 (Soluble fms-Like Tyrosine Kinase-1) Is Sufficient to Impair Spiral Arterial Remodeling in a Preeclampsia Mouse Model
    In: Hypertension , Jg. 78 2021, Nr. 4, S. 1067 – 1079
    DOI (Open Access)
  • Lassi, Maximilian; Tomar, Archana; Comas-Armangué, Gemma; Vogtmann, Rebekka; Dijkstra, Dorieke J.; Corujo, David; Gerlini, Raffaele; Darr, Jonatan; Scheid, Fabienne; Rozman, Jan; Aguilar-Pimentel, Antonio; Koren, Omry; Buschbeck, Marcus; Fuchs, Helmut; Marschall, Susan; Gailus-Durner, Valerie; De Angelis, Martin Hrabe; Plösch, Torsten; Gellhaus, Alexandra; Teperino, Raffaele
    Disruption of paternal circadian rhythm affects metabolic health in male offspring via nongerm cell factors
    In: Science Advances , Jg. 7 2021, Nr. 22, eabg6424
    DOI (Open Access)
  • Mach, Pawel; Andrikos, Dimitrios; Schmidt, Börge; Gellhaus, Alexandra; Rusch, Peter; Birdir, Cahit; Andrikos, Argyrios; Schmitt, Verena; Kimmig, Rainer; Singer, Bernhard B.; Köninger, Angela
    Evaluation of carcinoembryonic antigen-related cell adhesion molecule 1 blood serum levels in women at high risk for preeclampsia
    In: American Journal of Reproductive Immunology , Jg. 85 2021, Nr. 5, e13375
    DOI
  • Duan, Liyan; Schimmelmann, Manuela; Wu, Yuqing; Reisch, Beatrix; Faas, Marijke; Kimmig, Rainer; Winterhager, Elke; Köninger, Angela; Gellhaus, Alexandra
    CCN3 Signaling Is Differently Regulated in Placental Diseases Preeclampsia and Abnormally Invasive Placenta
    In: Frontiers in Endocrinology , Jg. 11 2020, 597549
    DOI, Online Volltext (Open Access)
  • Birdir, Cahit; Fox, Laura; Droste, Leonie; Frank, Mirjam; Fryze, Janina; Enekwe, Antje; Köninger, Angela; Kimmig, Rainer; Schmidt, Börge; Gellhaus, Alexandra
    MR-proANP, a cardiovascular biomarker to predict late-onset preeclampsia and intrauterine growth restricted fetuses
    In: Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health , Jg. 22 2020, S. 54 – 58
    DOI
  • Silini, Antonietta Rosa; Di Pietro, Roberta; Lang-Olip, Ingrid; Alviano, Francesco; Banerjee, Asmita; Basile, Mariangela; Borutinskaite, Veronika; Eissner, Günther; Gellhaus, Alexandra; Giebel, Bernd; Huang, Yong-Can; Janev, Aleksandar; Kreft, Mateja Erdani; Kupper, Nadja; Abadía-Molina, Ana Clara; Olivares, Enrique G.; Pandolfi, Assunta; Papait, Andrea; Pozzobon, Michela; Ruiz-Ruiz, Carmen; Soritau, Olga; Susman, Sergiu; Szukiewicz, Dariusz; Weidinger, Adelheid; Wolbank, Susanne; Huppertz, Berthold; Parolini, Ornella
    Perinatal Derivatives : Where Do We Stand? A Roadmap of the Human Placenta and Consensus for Tissue and Cell Nomenclature
    In: Frontiers in Bioengineering and Biotechnology , Jg. 8 2020, S. 610544
    DOI (Open Access)
  • Haase, Nadine; Foster, Donald J.; Cunningham, Mark W.; Bercher, Julia; Nguyen, Tuyen; Shulga-Morskaya, Svetlana; Milstein, Stuart; Shaikh, Sarfraz; Rollins, Jeff; Golic, Michaela; Herse, Florian; Kräker, Kristin; Bendix, Ivo; Serdar, Meray; Napieczynska, Hanna; Heuser, Arnd; Gellhaus, Alexandra; Thiele, Kristin; Wallukat, Gerd; Müller, Dominik N.; LaMarca, Babbette; Dechend, Ralf
    RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models
    In: The Journal of Clinical Investigation (JCI) , Jg. 130 2020, Nr. 6, S. 2928 – 2942
    DOI (Open Access)
  • Appel, Sarah; Grothe, Jon; Storck, Sarah; Janoschek, Ruth; Bae-Gartz, Inga; Wohlfarth, Maria; Handwerk, Marion; Hucklenbruch-Rother, Eva; Gellhaus, Alexandra; Dötsch, Jörg
    A Potential Role for GSK3β in Glucose-Driven Intrauterine Catch-Up Growth in Maternal Obesity
    In: Endocrinology , Jg. 160 2019, Nr. 2, S. 377 – 386
    DOI (Open Access)
  • Stojanovska, Violeta; Dijkstra, Dorieke J.; Vogtmann, Rebekka; Gellhaus, Alexandra; Scherjon, Sicco A.; Plösch, Torsten
    A double-hit pre-eclampsia model results in sex-specific growth restriction patterns
    In: Disease Models and Mechanisms (DMM) , Jg. 12 2019, Nr. 2, dmm035980
    DOI (Open Access)
  • Köninger, Angela; Iannaccone, Antonella; Hajder, Ensar; Frank, Mirjam; Schmidt, Börge; Schleussner, Ekkehard; Kimmig, Rainer; Gellhaus, Alexandra; Dieplinger, Hans
    Afamin predicts gestational diabetes in polycystic ovary syndrome patients preconceptionally
    In: Endocrine Connections , Jg. 8 2019, Nr. 5, S. 616 – 624
    DOI, Online Volltext (Open Access)
  • Vogtmann, Rebekka; Kühnel, Elisabeth; Dicke, Nikolai; Verkaik-Schakel, Rikst Nynke; Plösch, Torsten; Schorle, Hubert; Stojanovska, Violeta; Herse, Florian; Köninger, Angela; Kimmig, Rainer; Winterhager, Elke; Gellhaus, Alexandra
    Human sFLT1 leads to severe changes in placental differentiation and vascularization in a transgenic hsFLT1/rtTA FGR mouse model
    In: Frontiers in Endocrinology , Jg. 10 2019, 165
    DOI, Online Volltext (Open Access)
  • Köninger, Angela; Nguyen, Buu-Phuc; Gellhaus, Alexandra; Dröge, Freya; Kimmig, Rainer; Geisthoff, Urban
    Was Morbus Osler und Präeklampsie (nicht) gemeinsam haben
    In: Der Gynäkologe , Jg. 52 2019, Nr. 1, S. 52 – 58
    DOI
  • Köninger, Angela; Enekwe, Antje; Mach, Pawel; Andrikos, Dimitrios; Schmidt, Börge; Frank, Mirjam; Birdir, Cahit; Kimmig, Rainer; Gellhaus, Alexandra; Dieplinger, Hans
    Afamin : an early predictor of preeclampsia
    In: Archives of Gynecology and Obstetrics , Jg. 298 2018, Nr. 5, S. 1009 – 1016
    DOI (Open Access)
  • Köninger, Angela; Mathan, Annette; Mach, Pawel; Frank, Mirjam; Schmidt, Börge; Schleussner, Ekkehard; Kimmig, Rainer; Gellhaus, Alexandra; Dieplinger, Hans
    Is Afamin a novel biomarker for gestational diabetes mellitus? : A pilot study
    In: Reproductive Biology and Endocrinology , Jg. 16 2018, 30
    DOI (Open Access)
  • Birdir, C.; Droste, L.; Fox, L.; Frank, Mirjam; Fryze, J.; Enekwe, A.; Köninger, Angela; Kimmig, Rainer; Schmidt, Börge; Gellhaus, Alexandra
    Predictive value of sFlt-1, PlGF, sFlt-1/PlGF ratio and PAPP-A for late-onset preeclampsia and IUGR between 32 and 37 weeks of pregnancy
    In: Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health , Jg. 12 2018, S. 124 – 128
    DOI
  • Mach, Pawel; Nolte-Boenigk, Luisa; Droste, Leonie; Fox, Laura; Frank, Mirjam; Schmidt, Börge; Herse, Florian; Verlohren, Stefan; Wicherek, Lukasz; Iannaccone, Antonella; Birdir, Cahit; Andrikos, Dimitrios; Kimmig, Rainer; Gellhaus, Alexandra; Köninger, Angela
    Soluble B7-H4 blood serum levels are elevated in women at high risk for preeclampsia in the first trimester, as well as in patients with confirmed preeclampsia
    In: American Journal of Reproductive Immunology , Jg. 80 2018, Nr. 3, S. e12988
    DOI
  • Köninger, Angela; Kampmeier, Antje; Mach, Pawel; Schmidt, Börge; Strowitzki, Thomas; Kimmig, Rainer; Gellhaus, Alexandra
    Tight interplay in early pregnancy between follistatin and anti-mullerian hormone in women with polycystic ovarian syndrome (PCOS)
    In: Archives of Gynecology and Obstetrics , Jg. 297 2018, Nr. 5, S. 1307 – 1316
    DOI
  • Köninger, Angela; Kampmeier, Antje; Schmidt, Börge; Frank, Mirjam; Strowitzki, Thomas; Kimmig, Rainer; Gellhaus, Alexandra; Mach, Pawel
    Trends in anti-Müllerian hormone concentrations across different stages of pregnancy in women with polycystic ovary syndrome
    In: Reproductive BioMedicine online (RBM) , Jg. 37 2018, Nr. 3, S. 367 – 374
    DOI
  • Köninger, Angela; Schmidt, Börge; Damaske, Daniela; Birdir, Cahit; Enekwe, Antje; Kimmig, Rainer; Strowitzki, Thomas; Gellhaus, Alexandra
    Follistatin during pregnancy and its potential role as an ovarian suppressing agent
    In: European Journal of Obstetrics & Gynecology and Reproductive Biology , Jg. 212 2017, S. 150 – 154
    DOI
  • Birdir, Cahit; Fryze, Janina; Frölich, Stefanie; Schmidt, Markus; Köninger, Angela; Kimmig, Rainer; Schmidt, Börge; Gellhaus, Alexandra
    Impact of maternal serum levels of Visfatin, AFP, PAPP-A, sFlt-1 and PlGF at 11–13 weeks gestation on small for gestational age births
    In: The Journal of Maternal-Fetal & Neonatal Medicine , Jg. 30 2017, Nr. 6, S. 629 – 634
    DOI
  • Beygo, Jasmin; Küchler, Alma; Gillessen-Kaesbach, Gabriele; Albrecht, Beate; Eckle, Jonas; Eggermann, Thomas; Gellhaus, Alexandra; Kanber, Deniz; Kordaß, Ulrike; Lüdecke, Hermann-Josef; Purmann, Sabine; Rossier, Eva; van de Nes, Johannes; Van Der Werf, Ilse M; Wenzel, Maren; Wieczorek, Dagmar; Horsthemke, Bernhard; Buiting, Karin
    New insights into the imprinted MEG8-DMR in 14q32 and clinical and molecular description of novel patients with Temple syndrome
    In: European Journal of Human Genetics , Jg. 25 2017, Nr. 8, S. 935 – 945
    DOI
  • Kühnel, Elisabeth; Kleff, Veronika; Stojanovska, Violeta; Kaiser, Stephanie; Waldschütz, Ralph; Herse, Florian; Plösch, Torsten; Winterhager, Elke; Gellhaus, Alexandra
    Placental-Specific Overexpression of sFlt-1 Alters Trophoblast Differentiation and Nutrient Transporter Expression in an IUGR Mouse Model
    In: Journal of Cellular Biochemistry , Jg. 118 2017, Nr. 6, S. 1316 – 1329
    DOI
  • Mach, Pawel; Gellhaus, Alexandra; Prager, Sebastian; Moore, Tom; Wennemuth, Gunther; Kimmig, Rainer; Köninger, Angela; Singer, Bernhard B.
    Soluble CEACAM1 and CEACAM6 are differently expressed in blood serum of pregnant women during normal pregnancy
    In: American Journal of Reproductive Immunology , Jg. 78 2017, Nr. 4, S. e12700
    DOI
  • Winterhager, Elke; Gellhaus, Alexandra
    Transplacental Nutrient Transport Mechanisms of Intrauterine Growth Restriction in Rodent Models and Humans
    In: Frontiers in Physiology , Jg. 8 2017, S. 951
    DOI (Open Access)
  • Kipkeew, Friederike; Kirsch, Manuela; Klein, Diana; Wülling, Manuela; Winterhager, Elke; Gellhaus, Alexandra
    CCN1 (CYR61) and CCN3 (NOV) signaling drives human trophoblast cells into senescence and stimulates migration properties
    In: Cell Adhesion & Migration , Jg. 10 2016, Nr. 1-2, S. 163 – 178
    DOI (Open Access)
  • Kirsch, Michael; Kipkeew, Friederike; Klein, Diana; Wülling, Manuela; Winterhager, Elke; Gellhaus, Alexandra
    CCN3 signaling is dysregulated in the pregnancy disorder preeclampsia
    In: Journal of Reproductive Immunology , Jg. 115 2016, S. 71 – 71
    DOI
  • Grothaus, Katrin; Horsthemke, Bernhard; Wieczorek, Dagmar; Siebert, Reiner; Kolarova, Julia; Mikat, Barbara; Gellhaus, Alexandra; Kanber, Deniz
    Genome-wide methylation analysis of retrocopy-associated CpG islands and their genomic environment
    In: Epigenetics , Jg. 11 2016, Nr. 3, S. 216 – 226
    DOI (Open Access)
  • Nüsken, Eva; Gellhaus, Alexandra; Kühnel, Elisabeth; Swoboda, Isabelle; Wohlfahrt, Maria; Vohlen, Christina; Schneider, Holm; Dötsch, Jörg; Nüsken, Kai-Dietrich
    Increased Rat Placental Fatty Acid, but Decreased Amino Acid and Glucose Transporters Potentially Modify Intrauterine Programming
    In: Journal of Cellular Biochemistry , Jg. 117 2016, Nr. 7, S. 1594 – 1603
    DOI
  • Köninger, Angela; Schmidt, Börge; Mach, P.; Damaske, D.; Nießen, Stefanie; Kimmig, Rainer; Strowitzki, T.; Gellhaus, Alexandra
    Anti-Mullerian-Hormone during pregnancy and peripartum using the new Beckman Coulter AMH Gen II Assay
    In: Reproductive Biology and Endocrinology , Jg. 13 2015, Nr. 1, 86
    DOI (Open Access)
  • Mach, Pawel; Gellhaus, Alexandra; Wicherek, Lukasz; Schmidt, Börge; Kimmig, Rainer; Kasimir-Bauer, Sabine; Köninger, Angela
    Changes in the Blood Serum Levels of the Costimulatory Soluble B7-H4 Molecule in Pregnant Women During the Peripartal Phase
    In: American Journal of Reproductive Immunology , Jg. 74 2015, Nr. 3, S. 209 – 215
    DOI
  • Birdir, Cahit; Janssen, Katharina; Stanescu, Anca Daniela; Enekwe, Antje; Kasimir-Bauer, Sabine; Gellhaus, Alexandra; Kimmig, Rainer; Köninger, Angela
    Maternal serum copeptin, MR-proANP and procalcitonin levels at 11–13 weeks gestation in the prediction of preeclampsia
    In: Archives of Gynecology and Obstetrics , Jg. 292 2015, Nr. 5, S. 1033 – 1042
    DOI
  • Otto, Teresa; Gellhaus, Alexandra; Lüschen, Navina; Scheidler, Jan; Bendix, Ivo; Dunk, Caroline; Wolf, Nadine; Lennartz, Klaus; Köninger, Angela; Schmidt, Markus; Kimmig, Rainer; Fandrey, Joachim; Winterhager, Elke
    Oxygen Sensitivity of Placental Trophoblast Connexins 43 and 46 : A Role in Preeclampsia?
    In: Journal of Cellular Biochemistry , Jg. 116 2015, Nr. 12, S. 2924 – 2937
    DOI
  • Kibschull, Mark; Gellhaus, Alexandra; Carette, Diane; Segretain, Dominique; Pointis, Georges; Gilleron, Jerome
    Physiological roles of connexins and pannexins in reproductive organs
    In: Cellular and Molecular Life Sciences - CMLS , Jg. 72 2015, Nr. 15, S. 2879 – 2898
    DOI
  • Kaiser, Stephanie; Koch, Yvonne; Kühnel, Elisabeth; Sharma, Neha; Gellhaus, Alexandra; Kuckenberg, Peter; Schorle, Hubert; Winterhager, Elke
    Reduced gene dosage of Tfap2c impairs trophoblast lineage differentiation and alters maternal blood spaces in the mouse placenta
    In: Biology of Reproduction , Jg. 93 2015, Nr. 2, S. 31
    DOI (Open Access)
  • Pruis, M. G. M.; Gellhaus, Alexandra; Kühnel, E.; Lendvai, A.; Bloks, V. W.; Groen, A. K.; Plösch, T.
    Sex-specific placental differences as a contributor to sex-specific metabolic programming?
    In: Acta Physiologica , Jg. 215 2015, Nr. 3, S. 127 – 129
    DOI
  • Gellhaus, Alexandra; Nuesken, Eva; Swoboda, Isabelle; Kuehnel, Elisabeth; Wohlfahrt, Maria; Lippach, Gregor; Doetsch, Joerg; Nuesken, Kai-Dietri
    Altered placental expression levels of nutrient transporters after bilateral uterine artery ligation in the rat
    In: Placenta , Jg. 35 2014, Nr. 9, S. A41
    DOI
  • Kipkeew, Friederike; Klein, Diana; Wülling, Manuela; Whitley, Guy; Köninger, Angela; Winterhager, Elke; Gellhaus, Alexandra
    CCN3 (NOV) : A key player in trophoblast differentiation promoting cell cycle exit and migration of extravillous trophoblast cells and its role in preeclampsia
    In: Placenta , Jg. 35 2014, Nr. 9, S. A108
    DOI
  • Lechtermann, Carolin; Hauffa, Berthold; Herrmann, Ralf; Schündeln, Michael; Gellhaus, Alexandra; Schmidt, Markus; Grasemann, Corinna
    Maternal Vitamin D Status in Preeclampsia : Seasonal Changes Are Not Influenced by Placental Gene Expression of Vitamin D Metabolizing Enzymes
    In: PLoS ONE , Jg. 9 2014, Nr. 8, S. e105558
    DOI (Open Access)
  • Winterhager, Elke; Gellhaus, Alexandra
    The role of the CCN family of proteins in female reproduction
    In: Cellular and Molecular Life Sciences - CMLS , Jg. 71 2014, Nr. 12, S. 2299 – 2311
    DOI
  • Wagener, Jessica; Yang, Wei; Kazuschke, Kathrin; Winterhager, Elke; Gellhaus, Alexandra
    CCN3 regulates proliferation and migration properties in Jeg3 trophoblast cells via ERK1/2, akt and notch signalling
    In: Molecular Human Reproduction: MHR , Jg. 19 2013, Nr. 4, S. 237 – 249
    DOI
  • Winterhager, Elke; Gellhaus, Alexandra; Blois, Sandra M.; Hill, Lesley A.; Barr, Kevin J.; Kidder, Gerald M.
    Decidual angiogenesis and placental orientation are altered in mice heterozygous for a dominant loss-of-function Gja1 (Connexin43) mutation
    In: Biology of Reproduction , Jg. 89 2013, Nr. 5, S. 1 – 12
    DOI
  • Koch, Y.; van Fürden, B.; Kaiser, S.; Klein, D.; Kibschull, M.; Schorle, H.; Carpinteiro, Alexander; Gellhaus, Alexandra; Winterhager, Elke
    Connexin 31 (GJB3) deficiency in mouse trophoblast stem cells alters giant cell differentiation and leads to loss of oxygen sensing
    In: Biology of Reproduction , Jg. 87 2012, Nr. 2, S. 37
    DOI
  • Mikat, B; Gellhaus, Alexandra; Wagner, N; Birdir, C; Kimmig, Rainer; Köninger, Angela
    Early detection of maternal risk for preeclampsia
    In: ISRN Obstetrics and Gynecology 2012, S. 172808
    DOI
  • Bendix, Ivo; Schulze, Corina; Haefen, Clarissa von; Gellhaus, Alexandra; Endesfelder, Stefanie; Heumann, Rolf; Felderhoff-Müser, Ursula; Sifringer, Marco
    Erythropoietin Modulates Autophagy Signaling in the Developing Rat Brain in an In Vivo Model of Oxygen-Toxicity
    In: International Journal of Molecular Sciences (IJMS) , Jg. 13 2012, Nr. 10, S. 12939 – 12951
    DOI, Online Volltext (Open Access)
  • Kaiser, Stephanie; Koch, Yvonne; Gellhaus, Alexandra; Schorle, Hubert; Winterhager, Elke
    TCFAP2C dependent trophoblast lineage differentiation during placental development
    In: Placenta , Jg. 33 2012, Nr. 9, S. A68 – A68
  • Gellhaus, Alexandra; Wagener, Jessica; Yang, Wei; Wolf, Nadine; Dunk, CarolineE; Winterhager, Elke; Kaiser, Stephanie
    The CCN3 protein regulates proliferation and migration properties in JEG3 throphoblast cells via ERK1/2 art and notch signalling
    In: Placenta , Jg. 33 2012, Nr. 9, S. A70 – A70
  • Dunk, Caroline E.; Gellhaus, Alexandra; Drewlo, Sascha; Baczyk, Dora; Pötgens, Andy J.G.; Winterhager, Elke; Kingdom, John C.P.; Lye, Steven J.
    The molecular role of connexin 43 in human trophoblast cell fusion
    In: Biology of Reproduction , Jg. 86 2012, Nr. 4, S. 115
    DOI
  • Yang, Wei; Wagener, Jessica; Wolf, Nadine; Schmidt, Markus; Kimmig, Rainer; Winterhager, Elke; Gellhaus, Alexandra
    Impact of CCN3 (NOV) glycosylation on migration/invasion properties and cell growth of the choriocarcinoma cell line Jeg3
    In: Human Reproduction , Jg. 26 2011, Nr. 10, S. 2850 – 2860
    DOI
  • Dicke, Nikolai; Pielensticker, Nicole; Degen, Joachim; Hecker, Julia; Tress, Oliver; Bald, Tobias; Gellhaus, Alexandra; Winterhager, Elke; Willecke, Klaus
    Peripheral lymphangiogenesis in mice depends on ectodermal connexin-26 (Gjb2)
    In: Journal of Cell Science , Jg. 124 2011, Nr. 16, S. 2806 – 2815
    DOI (Open Access)
  • Gellhaus, Alexandra; Wagener, Jessica; Yang, Wei; Wolf, Nadine; Dunk, CarolineE; Schmidt, Markus; Kimmig, Rainer; Lye, StephenJ; Winterhager, Elke
    The oxygen-sensitive CCN3 protein regulates both, trophoblast migration/invasion and proliferation
    In: Placenta , Jg. 32 2011, Nr. 9, S. A61 – A61
  • Ugocsai, Peter; Hohenstatt, Antonia; Paragh, György; Liebisch, Gerhard; Langmann, Thomas; Wolf, Zsuzsanna; Weiss, Thomas; Groitl, Peter; Dobner, Thomas; Kasprzak, Piotr; Göbölös, László; Falkert, Andreas; Seelbach-Goebel, Birgit; Gellhaus, Alexandra; Winterhager, Elke; Schmidt, Markus; Semenza, Gregg L.; Schmitz, Gerd
    HIF-1beta determines ABCA1 expression under hypoxia in human macrophages
    In: The International Journal of Biochemistry & Cell Biology , Jg. 42 2010, Nr. 2, S. 241 – 252
    DOI
  • Gellhaus, Alexandra; Wotzlaw, Christoph; Otto, Teresa; Fandrey, Joachim; Winterhager, Elke
    More insights into the CCN3/connexin43 interaction complex and its role for signaling
    In: Journal of Cellular Biochemistry , Jg. 110 2010, Nr. 1, S. 129 – 140
    DOI
  • Wolf, Nadine; Yang, Wei; Dunk, Caroline E.; Gashaw, Isabella; Lye, Stephen J.; Ring, Thomas; Schmidt, Markus; Winterhager, Elke; Gellhaus, Alexandra
    Regulation of the Matricellular Proteins CYR61 (CCN1) and NOV (CCN3) by Hypoxia-Inducible Factor-1α and Transforming-Growth Factor-β3 in the Human Trophoblast
    In: Endocrinology , Jg. 151 2010, Nr. 6, S. 2835 – 2845
    DOI
  • Plösch, Torsten; Gellhaus, Alexandra; Straten, Esther van; Wolf, Nadine; Huijkman, Nicolette C.; Schmidt, Markus; Dunk, Caroline E.; Kuipers, Folkert C.; Winterhager, Elke
    The liver X receptor (LXR) and its target gene ABCA1 are regulated upon low oxygen in human trophoblast cells : A reason for alterations in preeclampsia?
    In: Placenta , Jg. 31 2010, Nr. 10, S. 910 – 918
    DOI
  • Banaz-Yaşar, Ferya; Tischka, Rabea; Iliakis, George; Winterhager, Elke; Gellhaus, Alexandra
    Cell line specific modulation of connexin43 expression after exposure to ionizing radiation
    In: Cell Communication and Adhesion , Jg. 12 2005, Nr. 5-6, S. 249 – 259
    DOI

    • Abstracts

  • Shi, Wenqin; Riedel, Alina; Bazzano, Maria V.; Hardardottir, Lilja; Köninger, Angela; Gellhaus, Alexandra; Solano, Maria E.
    Regulatory CD8+ T cells are modulated in healthy and preeclampsia pregnancies
    In: Journal of Reproductive Immunology , Jg. 159 2023, 104074
    DOI
  • Riedel, Alina; Bazzano, Maria V.; Vogtmann, Rebekka; Bao, Mian; Dewan, Monia; Shi, Wenqin; Kimmig, Rainer; Köninger, Angela; Bendix, Ivo; Plösch, Torsten; Solano, Maria E.; Gellhaus, Alexandra
    The immune and metabolic phenotype is changed in fetal livers upon systemic sFLT1 expression in preeclamptic mice which is linked to adverse offspring metabolic responses
    In: Journal of Reproductive Immunology , Jg. 159 2023, S. 104036
    DOI
  • Waldmann, A; Bazzano, MV; Hardardottir, L; Riedel, A; Gellhaus, Alexandra; Köninger, Angela; Solano, ME
    Postpartum tissue regeneration at the uterus
    In: Geburtshilfe und Frauenheilkunde , Jg. 82 2022, Nr. 10, S. e178
    DOI
  • Iannaccone, A; Reisch, B; Kimmig, Rainer; Köninger, Angela; Jahn, M; Gellhaus, Alexandra
    Therapeutischer Plasmaaustausch bei schwerer und früh einsetzender Präeklampsie : monozentrische Erfahrung über 7 Jahren
    In: Geburtshilfe und Frauenheilkunde , Jg. 82 2022, Nr. 10, S. e95
    DOI
  • Middendorf, Lisa; Gellhaus, Alexandra; Dathe, Anne-Kathrin; Bendix, Ivo; Reisch, Beatrix; Felderhoff-Müser, Ursula; Hüning, Britta
    The impact of increased maternal sFlt-1/PlGF ratio as a biomarker for preeclampsia on the motor outcome of preterm infants
    4th Congress of Joint European Neonatal Societies: Brain, Development and Imaging; 14–18 September 2021; Virtual Meeting,
    In: Pediatric Research , Jg. 90 2021, Nr. Suppl. 1, S. 5
    DOI (Open Access)
  • Andrikos, Dimitrios; Köninger, Angela; Andrikos, A; Kimmig, Rainer; Gellhaus, Alexandra; Schmitt, V; Schmidt, Börge; Singer, Bernhard B.; Mach, Pawel
    Evaluation der CEACAM-1 Level im Serum von Schwangeren im ersten Trimester bei hohem Risiko für Präeklampsie
    In: Geburtshilfe und Frauenheilkunde , Jg. 80 2020, Nr. 10, S. e151
    DOI
  • Andrikos, A; Andrikos, D; Gellhaus, Alexandra; Kimmig, Rainer; Schmidt, Börge; Köninger, Angela
    Evaluation des Verlaufs von sFlt-1/PlGF bei intrauteriner Wachstumsretardierung ohne und mit Präeklampsie
    In: Geburtshilfe und Frauenheilkunde , Jg. 80 2020, Nr. 10, S. e150 – e151
    DOI
  • Kipkeew, Friederike; Winterhager, Elke; Whitley, Guy; Klein, Diana; Wülling, Manuela; Gellhaus, Alexandra
    Matricellular CCN1 and CCN3 proteins are key regulators at the fetal-maternal interface by promoting cell cycle exit and migration of extravillous trophoblast cells
    In: Placenta , Jg. 34 2013, S. A87
    DOI
  • Gellhaus, Alexandra; Otto, Teresa; Wolf, N.; Scheidler, J.; Böngler, Kerstin; Dunk, C.; Schmidt, Markus; Kimmig, Rainer; Lennartz, K.; Winterhager, Elke; Kaiser, S.
    Regulation of placental connexins 43 and 46 upon low oxygen and its impact on preeclampsia
    International Federation of Placenta Associations Meeting 2012, 18 - 21 September 2012, Hiroshima, Japan,
    In: Placenta , Jg. 33 2012, Nr. 9, S. A86 – A86
    DOI
  • Gellhaus, Alexandra; Wagener, J.; Yang, W.; Wolf, N.; Dunk, Caroline Elizabeth; Schmidt, Markus; Kimmig, Rainer; Winterhager, Elke
    The CCN3 protein : Regulator of trophoblast proliferation and migration/invasion, and its contribution to preeclampsia
    In: Journal of Reproductive Immunology , Jg. 94 2012, Nr. 1, S. 71
    DOI
  • Gellhaus, Alexandra; Otto, Teresa; Wolf, Nadine; Scheidler, Jan; Böngler, Kerstin; Dunk, Caroline Elizabeth; Schmidt, Markus; Kimmig, Rainer; Lennartz, Klaus; Lye, Stephen J.; Winterhager, Elke
    The effect of oxygen on placental connexins 43 and 46 and its contribution to preeclampsia
    joint International Congress of the American Society for Reproductive Immunology (ASRI) & the European Society for Reproductive Immunology (ESRI), May 31 - June 2, 2012, Hamburg, Germany,
    In: Journal of Reproductive Immunology , Jg. 94 2012, Nr. 1, S. 34 – 35
    DOI
  • Yang, Wei; Wagener, Jessica; Wolf, N.; Schmidt, Markus; Kimmig, Rainer; Winterhager, Elke; Gellhaus, Alexandra
    The role of CCN3 (NOV) on migratory and invasive properties of trophoblast cells
    In: European Journal of Cell Biology (EJCB) , Jg. 89 2010, Nr. Suppl. 60, S. 11 – 11

    • Bücher/Sammelwerke/Tagungsbände

  • Gellhaus, Alexandra
    CCN-Proteine CYR61 (CCN1) und NOV (CCN3) : Funktion in der Plazentaentwicklung und Rolle in der Schwangerschaftserkrankung Präeklampsie
    Duisburg, Essen 2013

    • Dissertation

  • Gellhaus, Alexandra
    Einfluß verschiedener Gap Junction-Kanäle auf das Proliferations-, Invasions- und Differenzierungsverhalten der Chorionkarzinomzellinie Jeg 3
    Duisburg-Essen 2003
    Online Volltext

    • Poster / Posterbeiträge

  • Gellhaus, Alexandra; Otto, Teresa; Wolf, Nadine; Scheidler, Jan; Böngler, Kerstin; Dunk, Caroline; Schmidt, Markus; Kimmig, Rainer; Lennartz, Klaus; Lye, Stephen J.; Winterhager, Elke
    The effect of oxygen on placental connexins 43 and 46 and its contribution to preeclampsia
    International Federation of Placenta Associations Meeting 2011, 14 - 17 September 2011, Geilo, Norway,
    In: Placenta , Jg. 32 2011, Nr. 9, S. A86
    DOI