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Innere Klinik (Tumorforschung)
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SoSe 2025
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WiSe 2024
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SoSe 2024
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WiSe 2023
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SoSe 2023
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinomaIn: Cell Reports , Jg. 44 2025, Nr. 4, 115541DOI (Open Access)
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The Lung Cancer Autochthonous Model Gene Expression Database Enables Cross-Study Comparisons of the Transcriptomic Landscapes Across Mouse ModelsIn: Cancer Research , Jg. 85 2025, Nr. 10, S. 1769 – 1783DOI (Open Access)
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KDM5B predicts temozolomide-resistant subclones in glioblastomaIn: iScience , Jg. 27 2024, Nr. 1, 108596DOI (Open Access)
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A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in GlioblastomaIn: Clinical Cancer Research , Jg. 29 2023, Nr. 2, S. 488 – 500DOI (Open Access)
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Decrypting drug actions and protein modifications by dose- and time-resolved proteomicsIn: Science , Jg. 380 2023, Nr. 6640, S. 93 – 101DOI (Open Access)
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Altered mitochondria functionality defines a metastatic cell state in lung cancer and creates an exploitable vulnerabilityIn: Cancer Research , Jg. 81 2021, Nr. 3, S. 567 – 579DOI (Open Access)
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HER2 mediates clinical resistance to the KRASG¹²C inhibitor sotorasib, which is overcome by co-targeting SHP2In: European Journal of Cancer (EJC) , Jg. 159 2021, S. 16 – 23
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Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasisIn: Cell Reports , Jg. 37 2021, Nr. 8, 110056DOI, Online Volltext (Open Access)
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Unraveling tumor heterogeneity by using DNA barcoding technologies to develop personalized treatment strategies in advanced-stage pdacIn: Cancers , Jg. 13 2021, Nr. 16, 4187DOI, Online Volltext (Open Access)
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„Yes, we (s)can“ : Molekulare Barcodes in der Tumorforschung für neue in vivo-Screening VerfahrenIn: Unikate: Berichte aus Forschung und Lehre 2021, Nr. 56 : "Junge Wilde" - Die nächste Generation, S. 22 – 29DOI, Online Volltext (Open Access)
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Cancer cells stock up in lymph vessels to surviveIn: Nature , Jg. 585 2020, Nr. 7823, S. 36 – 37DOI (Open Access)
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Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasisIn: Oncogenesis , Jg. 9 2020, Nr. 11, S. 102DOI, Online Volltext (Open Access)
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Axon-like protrusions promote small cell lung cancer migration and metastasisIn: eLife , Jg. 8 2019, S. e50616DOI (Open Access)
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Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistanceIn: Scientific Reports , Jg. 8 2018, Nr. 1, S. 14008DOI (Open Access)
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BLIMP1 induces transient metastatic heterogeneity in pancreatic cancerIn: Cancer Discovery , Jg. 7 2017, Nr. 10, S. 1184 – 1199
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Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axisIn: Nature Medicine , Jg. 23 2017, Nr. 3, S. 291 – 300DOI (Open Access)
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An in vivo multiplexed small-molecule screening platformIn: Nature Methods , Jg. 13 2016, Nr. 10, S. 883 – 889DOI (Open Access)
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Modeling therapy response and spatial tissue distribution of erlotinib in pancreatic cancerIn: Molecular Cancer Therapeutics , Jg. 15 2016, Nr. 5, S. 1145 – 1152DOI (Open Access)
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Nfib Promotes Metastasis through a Widespread Increase in Chromatin AccessibilityIn: Cell , Jg. 166 2016, Nr. 2, S. 328 – 342DOI (Open Access)
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Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editingIn: Genes and Development , Jg. 29 2015, Nr. 14, S. 1576 – 1585DOI (Open Access)
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Identification of a Ninein (NIN) mutation in a family with spondyloepimetaphyseal dysplasia with joint laxity (leptodactylic type)-like phenotypeIn: Matrix Biology , Jg. 32 2013, Nr. 7-8, S. 387 – 392
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EGF Receptor Is Required for KRAS-Induced Pancreatic TumorigenesisIn: Cancer Cell , Jg. 22 2012, Nr. 3, S. 304 – 317DOI (Open Access)
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MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancerIn: PLoS ONE , Jg. 7 2012, Nr. 6, S. e39424DOI (Open Access)
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An inducible Tet-Off-H2B-GFP lentiviral reporter vector for detection and in vivo isolation of label-retaining cellsIn: Experimental Cell Research , Jg. 316 2010, Nr. 11, S. 1885 – 1895
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Identification of epidermal pdx1 expression discloses different roles of notch1 and notch2 in murine krasG¹²D-induced skin carcinogenesis in vivoIn: PLoS ONE , Jg. 5 2010, Nr. 10, S. e13578DOI (Open Access)
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Predicting and targeting clonally expanding, tmz-resistant tumor cells in glioblastoma
28th Annual Scientific Meeting of the Society-for-Neuro-Oncology (SNO); NOV 15-19, 2023; Vancouver, Canada,In: Neuro-Oncology , Jg. 25 2023, Nr. Suppl. 5, S. v110 – v110 -
Combining Patient-Derived Xenografts and Barcoding Technology to Evaluate Response to Targeted Therapies in ALK+NSCLCIn: Journal of Thoracic Oncology , Jg. 17 2022, Nr. 9, S. 611
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Targeting SHP2 Reverts Oncogenic Mediated Resistance to KRAS-G12C InhibitionIn: Journal of Thoracic Oncology , Jg. 17 2022, Nr. 9, S. S586 – S587
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MA17.07 Identification of AHR as a Novel Regulator of Lung Cancer MetastasisIn: Journal of Thoracic Oncology , Jg. 14 2019, Nr. 10, Supplement, S. S319DOI (Open Access)
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Multiplexed in vivo small molecule screening for immediate drug repositioning reveals novel therapeutic targets in metastatic pancreatic cancer
AACR Special Conference: Advances in Modeling Cancer in Mice: Technology, Biology, and Beyond; September 24-27, 2017; Orlando, Florida,In: Cancer Research , Jg. 78 2018, Nr. 10, S. 34 – 35 -
Barcoding Technology for Multiplexed Analysis of Metastatic Ability In VivoIn: Metastasis: Methods and Protocols / Stein, Ulrike S. (Hrsg.) 2021, S. 239 – 251