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Prof. Dr. rer. nat. Alexander Schramm

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Metzenmacher, Martin; Hegedüs, Balazs; Forster, Jan; Schramm, Alexander; Horn, Peter; Klein, Christoph A.; Bielefeld, Nicola; Ploenes, Till; Aigner, Clemens; Theegarten, Dirk; Schildhaus, Hans-Ulrich; Siveke, Jens; Schuler, Martin; Lueong, Smiths S.
    Combined multimodal ctDNA analysis and radiological imaging for tumor surveillance in Non-small cell lung cancer
    In: Translational Oncology Jg. 15 (2022) Nr. 1,
    ISSN: 1936-5233; 1944-7124
    Online Volltext: dx.doi.org/ (Open Access)
  • Tüns, Alicia Isabell; Hartmann, Till; Magin, Simon; González, Rocío Chamorro; Henssen, Anton George; Rahmann, Sven; Schramm, Alexander; Köster, Johannes
    Detection and Validation of Circular DNA Fragments Using Nanopore Sequencing
    In: Frontiers in Genetics Jg. 13 (2022)
    ISSN: 1664-8021
    Online Volltext: dx.doi.org/ (Open Access)
  • Voeltzke, Kai; Scharov, Katerina; Funk, Cornelius Maximilian; Kahler, Alisa; Picard, Daniel; Hauffe, Laura; Orth, Martin F.; Remke, Marc; Esposito, Irene; Kirchner, Thomas; Schramm, Alexander; Rotblat, Barak; Grünewald, Thomas G. P.; Reifenberger, Guido; Leprivier, Gabriel
    EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma
    In: Cell Death Discovery Jg. 8 (2022) Nr. 1,
    ISSN: 2058-7716
    Online Volltext: dx.doi.org/ (Open Access)
  • Thumser-Henner, Clotilde; Oeck, Sebastian; Kalmbach, Sophie; Forster, Jan; Kindl, Franziska; Sak, Ali; Schramm, Alexander; Schuler, Martin
    Syntaxin 18 regulates the DNA damage response and epithelial-to-mesenchymal transition to promote radiation resistance of lung cancer
    In: Cell Death and Disease Jg. 13 (2022) Nr. 6,
    ISSN: 2041-4889
    Online Volltext: dx.doi.org/ (Open Access)
  • Metzenmacher, Martin; Hegedüs, Balazs; Forster, Jan; Schramm, Alexander; Horn, Peter; Klein, Christoph A.; Bielefeld, Nicola; Ploenes, Till; Aigner, Clemens; Siveke, Jens; Schuler, Martin; Lueong, Smiths S.
    The clinical utility of cfRNA for disease detection and surveillance : A proof of concept study in non-small cell lung cancer
    In: Thoracic Cancer (2022) in press
    ISSN: 1759-7714; 1759-7706
    Online Volltext: dx.doi.org/ (Open Access)
  • Menke, Katrin; Schwermer, Melanie; Eisenbraun, Jürgen; Schramm, Alexander; Zuzak, Tycho Jan
    Anticancer Effects of Viscum album Fraxini Extract on Medulloblastoma Cells in vitro
    In: Complementary Medicine Research Jg. 28 (2021) Nr. 1, S. 15 - 22
    ISSN: 2504-2106; 2504-2092
    Online Volltext: dx.doi.org/
  • Korff, Johanna Maria; Menke, Katrin; Schwermer, Melanie; Falke, Katharina; Schramm, Alexander; Längler, Alfred; Zuzak, Tycho Jan
    Antitumoral Effects of Curcumin (Curcuma longa L.) and Thymoquinone (Nigella sativa L.) on Neuroblastoma Cell Lines
    In: Complementary Medicine Research Jg. 28 (2021) Nr. 2, S. 164 - 168
    ISSN: 2504-2106; 2504-2092
    Online Volltext: dx.doi.org/
  • Seier, Johanna A.; Reinhardt, Julia; Saraf, Kritika; Ng, Susanna S.; Layer, Julian P.; Corvino, Dillon; Althoff, Kristina; Giordano, Frank A.; Schramm, Alexander; Fischer, Matthias; Hölzel, Michael
    Druggable epigenetic suppression of interferon-induced chemokine expression linked to MYCN amplification in neuroblastoma
    In: Journal for ImmunoTherapy of Cancer Jg. 9 (2021) Nr. 5,
    ISSN: 2051-1426
    Online Volltext: dx.doi.org/ (Open Access)
  • Ho, Cassandra S. L.; Tüns, Alicia I.; Schildhaus, Hans-Ulrich; Wiesweg, Marcel; Grüner, Barbara M.; Hegedus, Balazs; Schuler, Martin; Schramm, Alexander; Oeck, Sebastian
    HER2 mediates clinical resistance to the KRASG¹²C inhibitor sotorasib, which is overcome by co-targeting SHP2
    In: European Journal of Cancer (EJC) Jg. 159 (2021) S. 16 - 23
    ISSN: 1879-0852; 0959-8049; 1879-2995
    Online Volltext: dx.doi.org/
  • Hassiepen, Christina; Soni, Aashish; Rudolf, Ines; Boron, Vivian; Oeck, Sebastian; Iliakis, George; Schramm, Alexander
    NTRK1/TrkA activation overrides the G₂ /M-checkpoint upon irradiation
    In: Cancers Jg. 13 (2021) Nr. 23,
    ISSN: 2072-6694
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Funke, Lukas; Bracht, Thilo; Oeck, Sebastian; Schork, Karin; Stepath, Markus; Dreesmann, Sabine; Eisenacher, Martin; Sitek, Barbara; Schramm, Alexander
    Ntrk1/trka signaling in neuroblastoma cells induces nuclear reorganization and intra‐nuclear aggregation of lamin a/c
    In: Cancers Jg. 13 (2021) Nr. 21,
    ISSN: 2072-6694
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Menke, Katrin; Schwermer, Melanie; Schramm, Alexander; Zuzak, Tycho Jan
    Präklinische Untersuchungen von Wechselwirkungen zwischen Mistel und Radio- oder Chemotherapie auf pädiatrische Tumorzellen
    In: Complementary Medicine Research (2021) in press
    ISSN: 2504-2106; 2504-2092
    Online Volltext: dx.doi.org/
  • Dorsch, Madeleine; Kowalczyk, Manuela; Planque, Mélanie; Heilmann, Geronimo; Urban, Sebastian; Dujardin, Philip; Forster, Jan; Ueffing, Kristina; Nothdurft, Silke; Oeck, Sebastian; Paul, Annika; Liffers, Sven T.; Kaschani, Farnusch; Kaiser, Markus; Schramm, Alexander; Siveke, Jens; Winslow, Monte M.; Fendt, Sarah-Maria; Nalbant, Perihan; Grüner, Barbara M.
    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
    In: Cell Reports Jg. 37 (2021) Nr. 8,
    ISSN: 2211-1247
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Ahmadov, Ulvi; Picard, Daniel; Bartl, Jasmin; Silginer, Manuela; Trajkovic-Arsic, Marija; Qin, Nan; Blümel, Lena; Wolter, Marietta; Lim, Jonathan K. M.; Pauck, David; Winkelkotte, Alina Marie; Melcher, Marlen; Langini, Maike; Marquardt, Viktoria; Sander, Felix; Stefanski, Anja; Steltgens, Sascha; Hassiepen, Christina; Kaufhold, Anna; Meyer, Frauke-Dorothee; Seibt, Annette; Kleinesudeik, Lara; Hain, Anika; Münk, Carsten; Knobbe-Thomsen, Christiane Brigitte; Schramm, Alexander; Fischer, Ute; Leprivier, Gabriel; Stühler, Kai; Fulda, Simone; Siveke, Jens; Distelmaier, Felix; Borkhardt, Arndt; Weller, Michael; Roth, Patrick; Reifenberger, Guido; Remke, Marc
    The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma
    In: Cell Death & Disease Jg. 12 (2021) Nr. 10,
    ISSN: 2041-4889
    Online Volltext: dx.doi.org/ (Open Access)
  • Nothdurft, Silke; Thumser-Henner, Clotilde; Breitenbücher, Frank; Okimoto, Ross A.; Dorsch, Madeleine; Opitz, Christiane A.; Sadik, Ahmed; Esser, Charlotte; Hölzel, Michael; Asthana, Saurabh; Forster, Jan; Beisser, Daniela; Kalmbach, Sophie; Grüner, Barbara M.; Bivona, Trever G.; Schramm, Alexander; Schuler, Martin
    Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis
    In: Oncogenesis Jg. 9 (2020) Nr. 11, S. 102
    ISSN: 2157-9024
    Online Volltext: dx.doi.org/ (Open Access)
  • Stockhammer, Paul; Ho, Cassandra Su Lyn; Hegedus, Luca; Lotz, Gabor; Molnár, Eszter; Bankfalvi, Agnes; Herold, Thomas; Kalbourtzis, Stavros; Ploenes, Till; Eberhardt, Wilfried; Schuler, Martin; Aigner, Clemens; Schramm, Alexander; Hegedus, Balazs
    HDAC inhibition synergizes with ALK inhibitors to overcome resistance in a novel ALK mutated lung adenocarcinoma model
    In: Lung Cancer Jg. 144 (2020) S. 20 - 29
    ISSN: 1872-8332; 0169-5002
    Online Volltext: dx.doi.org/
  • Lu, Yuhong; Liu, Yanfeng; Oeck, Sebastian; Zhang, Gary J.; Schramm, Alexander; Glazer, Peter M.
    Hypoxia Induces Resistance to EGFR Inhibitors in Lung Cancer Cells via Upregulation of FGFR1 and the MAPK Pathway
    In: Cancer Research Jg. 80 (2020) Nr. 21, S. 4655 - 4667
    ISSN: 0008-5472; 1538-7445; 0099-7013; 0099-7374
    Online Volltext: dx.doi.org/ (Open Access)
  • Pietzka, Sebastian; Kämmerer, Peer W.; Pietzka, Silke; Schramm, Alexander; Lampl, Lorenz; Lefering, Rolf; Bieler, Dan; Kulla, Martin
    Maxillofacial injuries in severely injured patients after road traffic accidents—a retrospective evaluation of the TraumaRegister DGU® 1993–2014
    In: Clinical Oral Investigations Jg. 24 (2020) Nr. 1, S. 503 - 513
    ISSN: 1436-3771; 1432-6981
    Online Volltext: dx.doi.org/ (Open Access)
  • Tjaden, Britta; Baum, Katharina; Marquardt, Viktoria; Simon, Mareike; Trajkovic-Arsic, Marija; Kouril, Theresa; Siebers, Bettina; Lisec, Jan; Siveke, Jens; Schulte, Johannes H.; Benary, Uwe; Remke, Marc; Wolf, Jana; Schramm, Alexander
    N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma
    In: Scientific Reports Jg. 10 (2020) Nr. 1, S. 7157
    ISSN: 2045-2322
    Online Volltext: dx.doi.org/ (Open Access)
  • Metzenmacher, Martin; Váraljai, Renáta; Hegedüs, Balazs; Cima, Igor; Forster, Jan; Schramm, Alexander; Scheffler, Björn; Horn, Peter; Klein, Christoph A.; Szarvas, Tibor; Reis, Henning; Bielefeld, Nicola; Rösch, Alexander; Aigner, Clemens; Kunzmann, Volker; Wiesweg, Marcel; Siveke, Jens; Schuler, Martin; Lueong, Smiths S.
    Plasma next generation sequencing and droplet digital-qpcr-based quantification of circulating cell-free rna for noninvasive early detection of cancer
    In: Cancers Jg. 12 (2020) Nr. 2, S. 353
    ISSN: 2072-6694
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Oeck, Sebastian; Tüns, Alicia I.; Hurst, Sebastian; Schramm, Alexander
    Streamlining quantitative analysis of long RNA sequencing reads
    In: International Journal of Molecular Sciences (IJMS) Jg. 21 (2020) Nr. 19, S. 7259
    ISSN: 1422-0067; 1661-6596
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Ali, Solin; Toews, Karin; Schwiebert, Silke; Klaus, Anika; Winkler, Annika; Grunewald, Laura; Oevermann, Lena; Deubzer, Hedwig E.; Tüns, Alicia; Jensen, Michael C.; Henssen, Anton G.; Eggert, Angelika; Schulte, Johannes H.; Schwich, Esther; Rebmann, Vera; Schramm, Alexander; Künkele, Annette
    Tumor-Derived Extracellular Vesicles Impair CD171-Specific CD4⁺ CAR T Cell Efficacy
    In: Frontiers in Immunology Jg. 11 (2020) S. 531
    ISSN: 1664-3224
    Online Volltext: dx.doi.org/ (Open Access)
  • Schwermer, Melanie; Hiber, Michaela; Dreesmann, Sabine; Rieb, Anja; Theißen, Jessica; Herold, Thomas; Schramm, Alexander; Temming, Petra; Steenpass, Laura
    Comprehensive characterization of RB1 mutant and MYCN amplified retinoblastoma cell lines
    In: Experimental Cell Research Jg. 375 (2019) Nr. 2, S. 92 - 99
    ISSN: 0014-4827; 1090-2422
    Online Volltext: dx.doi.org/ (Open Access)
  • Wilde, F.; Krauß, O.; Sakkas, A.; Mascha, F.; Pietzka, S.; Schramm, Alexander
    Custom wave-shaped CAD/CAM orbital wall implants for the management of post-enucleation socket syndrome
    In: Journal of Cranio-Maxillofacial Surgery Jg. 47 (2019) Nr. 9, S. 1398 - 1405
    ISSN: 1878-4119; 1010-5182
    Online Volltext: dx.doi.org/
  • Reßing, Nina; Marquardt, Viktoria; Gertzen, Christoph G.W.; Schöler, Andrea; Schramm, Alexander; Kurz, Thomas; Gohlke, Holger; Aigner, Achim; Remke, Marc; Hansen, Finn K.
    Design, synthesis and biological evaluation of β-peptoid-capped HDAC inhibitors with anti-neuroblastoma and anti-glioblastoma activity
    In: MedChemComm Jg. 10 (2019) Nr. 7, S. 1109 - 1115
    ISSN: 2040-2511; 2040-2503
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Sakkas, Andreas; Winter, Karsten; Rath, Maximilian; Mascha, Frank; Pietzka, Sebastian; Schramm, Alexander; Wilde, Frank
    Factors influencing the long-term prognosis of root tip resected teeth
    In: GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW Jg. 8 (2019) S. 13
    ISSN: 2193-8091
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Brown, Peter; RELISH Consortium; Zhou, Yaoqi; Klump, Hannes; Rusch, Peter F.; Schramm, Alexander; Ranft, Andreas; Rassaf, Tienush
    Large expert-curated database for benchmarking document similarity detection in biomedical literature search
    In: Database: The Journal of Biological Databases and Curation Jg. 2019 (2019) S. 1 - 67
    ISSN: 1758-0463
    Online Volltext: dx.doi.org/ (Open Access)
  • Menke, Katrin; Schwermer, Melanie; Schramm, Alexander; Zuzak, Tycho J.
    Preclinical Evaluation of Antitumoral and Cytotoxic Properties of Viscum album Fraxini Extract on Pediatric Tumor Cells
    In: Planta Medica Jg. 85 (2019) Nr. 14-15, S. 1150 - 1159
    ISSN: 1439-0221; 0032-0943
    Online Volltext: dx.doi.org/
  • Han, Youjia; Lindner, Sven; Bei, Yi; Garcia, Heathcliff Dorado; Timme, Natalie; Althoff, Kristina; Odersky, Andrea; Schramm, Alexander; Lissat, Andrej; Künkele, Annette; Deubzer, Hedwig E.; Eggert, Angelika; Schulte, Johannes; Henssen, Anton G.
    Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma
    In: Cancer Letters Jg. 455 (2019) S. 24 - 33
    ISSN: 0304-3835
    Online Volltext: dx.doi.org/
  • Zuzak, Tycho Jan; Falke, Katharina; Felenda, Jessica; Beckmann, Christiane; Stintzing, Florian; Voigt, Anette; Menke, Katrin; Schramm, Alexander; Schwermer, Melanie
    Taraxacum officinale extract induces antitumorigenic effects in ovarian carcinoma cell lines
    In: European Journal of Gynaecological Oncology (EJGO) Jg. 40 (2019) Nr. 1, S. 106 - 112
    ISSN: 0392-2936
    Online Volltext: dx.doi.org/
  • Telschow, T.; Wilde, F.; Pietzka, S.; Schramm, Alexander; Mascha, F.
    Unbreakable? – Frakturen patientenspezifischer Implantate nach alloplastischer Unterkieferrekonstruktion
    In: Der MKG-Chirurg Jg. 12 (2019) Nr. 4, S. 263 - 267
    ISSN: 1865-9659; 1865-9667
    Online Volltext: dx.doi.org/
  • Ackermann, Sandra; Cartolano, Maria; Hero, Barbara; Welte, Anne; Kahlert, Yvonne; Roderwieser, Andrea; Bartenhagen, Christoph; Walter, Esther; Gecht, Judith; Kerschke, Laura; Volland, Ruth; Menon, Roopika; Heuckmann, Johannes M.; Gartlgruber, Moritz; Hartlieb, Sabine; Henrich, Kai-Oliver; Okonechnikov, Konstantin; Altmüller, Janine; Nürnberg, Peter; Lefever, Steve; De Wilde, Bram; Sand, Frederik; Ikram, Fakhera; Rosswog, Carolina; Fischer, Janina; Theissen, Jessica; Hertwig, Falk; Singhi, Aatur D.; Simon, Thorsten; Vogel, Wenzel; Perner, Sven; Krug, Barbara; Schmidt, Matthias; Rahmann, Sven; Achter, Viktor; Lang, Ulrich; Vokuhl, Christian; Ortmann, Monika; Büttner, Reinhard; Eggert, Angelika; Speleman, Frank; O’Sullivan, Roderick J.; Thomas, Roman K.; Berthold, Frank; Vandesompele, Jo; Schramm, Alexander; Westermann, Frank; Schulte, Johannes; Peifer, Martin; Fischer, Matthias
    A mechanistic classification of clinical phenotypes in neuroblastoma
    In: Science Jg. 362 (2018) Nr. 6419, S. 1165 - 1170
    ISSN: 1095-9203; 0036-8075
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Schulte, Marc; Köster, Johannes; Rahmann, Sven; Schramm, Alexander
    Cancer evolution, mutations, and clonal selection in relapse neuroblastoma
    In: Cell and Tissue Research Jg. 372 (2018) Nr. 2, S. 263 - 268
    ISSN: 0302-766X; 1432-0878
    Online Volltext: dx.doi.org/
  • Zeka, Fjoralba; Decock, Anneleen; Van Goethem, Alan; Vanderheyden, Katrien; Demuynck, Fleur; Lammens, Tim; Helsmoortel, Hetty H.; Vermeulen, Joëlle; Noguera, Rosa; Berbegall, Ana P.; Combaret, Valérie; Schleiermacher, Gudrun; Laureys, Geneviève; Schramm, Alexander; Schulte, Johannes; Rahmann, Sven; Bienertová-Vašků, Julie; Mazánek, Pavel; Jeison, Marta; Ash, Shifra; Hogarty, Michael D.; Moreno-Smith, Mirthala; Barbieri, Eveline; Shohet, Jason; Berthold, Frank; Van Maerken, Tom; Speleman, Frank; Fischer, Matthias; De Preter, Katleen; Mestdagh, Pieter; Vandesompele, Jo
    Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients
    In: JCI Insight Jg. 3 (2018) Nr. 23, S. e97021
    ISSN: 2379-3708
    Online Volltext: dx.doi.org/ (Open Access)
  • Pieper, Natalia; Zaremba, Anne; Leonardelli, Sonia; Harbers, Franziska Noelle; Schwamborn, Marion; Lübcke, Silke; Schrörs, Barbara; Baingo, Jolanthe; Schramm, Alexander; Haferkamp, Sebastian; Seifert, Ulrike; Sucker, Antje; Lennerz, Volker; Wölfel, Thomas; Schadendorf, Dirk; Schilling, Bastian; Paschen, Annette; Zhao, Fang
    Evolution of melanoma cross-resistance to CD8⁺ T cells and MAPK inhibition in the course of BRAFi treatment
    In: OncoImmunology Jg. 7 (2018) Nr. 8, S. e1450127
    ISSN: 2162-402X; 2162-4011
    Online Volltext: dx.doi.org/
  • Sakkas, Andreas; Schramm, Alexander; Winter, Karsten; Wilde, Frank
    Risk factors for post-operative complications after procedures for autologous bone augmentation from different donor sites
    In: Journal of Cranio-Maxillofacial Surgery Jg. 46 (2018) Nr. 2, S. 312 - 322
    ISSN: 1878-4119; 1010-5182
    Online Volltext: dx.doi.org/
  • Menke, K.; Schwermer, M.; Felenda, J.; Beckmann, C.; Stintzing, F.; Schramm, Alexander; Zuzak, T.J.
    Taraxacum officinale extract shows antitumor effects on pediatric cancer cells and enhance mistletoe therapy
    In: Complementary Therapies in Medicine Jg. 40 (2018)
    ISSN: 1873-6963; 0965-2299
    Online Volltext: dx.doi.org/
  • De Wilde, Bram; Beckers, Anneleen; Lindner, Sven; Kristina, Althoff; De Preter, Katleen; Depuydt, Pauline; Mestdagh, Pieter; Sante, Tom; Lefever, Steve; Hertwig, Falk; Peng, Zhiyu; Shi, Le-Ming; Lee, Sangkyun; Vandermarliere, Elien; Martens, Lennart; Menten, Björn; Schramm, Alexander; Fischer, Matthias; Schulte, Johannes; Vandesompele, Jo; Speleman, Frank
    The mutational landscape of MYCN, Lin28b and ALKF1174L driven murine neuroblastoma mimics human disease
    In: OncoTarget Jg. 9 (2018) Nr. 9, S. 8334 - 8349
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/ (Open Access)
  • Batzke, Katharina; Büchel, Gabriele; Hansen, Wiebke; Schramm, Alexander
    TrkB-Target Galectin-1 Impairs Immune Activation and Radiation Responses in Neuroblastoma : Implications for Tumour Therapy
    In: International Journal of Molecular Sciences (IJMS) Jg. 19 (2018) Nr. 3, S. 718
    ISSN: 1422-0067; 1661-6596
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Moreno, Lucas; Caron, Hubert; Geoerger, Birgit; Eggert, Angelika; Schleiermacher, Gudrun; Brock, Penelope; Valteau-Couanet, Dominique; Chesler, Louis; Schulte, Johannes H.; De Preter, Katleen; Molenaar, Jan; Schramm, Alexander; Eilers, Martin; Van Maerken, Tom; Johnsen, John Inge; Garrett, Michelle; George, Sally L.; Tweddle, Deborah A.; Kogner, Per; Berthold, Frank; Koster, Jan; Barone, Giuseppe; Tucker, Elizabeth R.; Marshall, Lynley; Herold, Ralf; Sterba, Jaroslav; Norga, Koen; Vassal, Gilles; Pearson, Andrew D.J.
    Accelerating drug development for neuroblastoma - New Drug Development Strategy : an Innovative Therapies for Children with Cancer, European Network for Cancer Research in Children and Adolescents and International Society of Paediatric Oncology Europe Neuroblastoma project
    In: Expert Opinion on Drug Discovery Jg. 12 (2017) Nr. 8, S. 801 - 811
    ISSN: 1746-045X; 1746-0441
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Layer, Julian P.; Kronmüller, Marie T.; Quast, Thomas; Boorn-Konijnenberg, Debby van den; Effern, Maike; Hinze, Daniel; Althoff, Kristina; Schramm, Alexander; Westermann, Frank; Peifer, Martin; Hartmann, Gunther; Tüting, Thomas; Kolanus, Waldemar; Fischer, Matthias; Schulte, Johannes; Hölzel, Michael
    Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression
    In: OncoImmunology Jg. 6 (2017) Nr. 6,
    ISSN: 2162-402X; 2162-4011
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Shpacovitch, Victoria; Sidorenko, Irina; Lenssen, Jan Eric; Temchura, Vladimir; Weichert, Frank; Müller, Heinrich; Überla, Klaus; Zybin, Alexander; Schramm, Alexander; Hergenröder, Roland
    Application of the PAMONO-sensor for quantification of microvesicles and determination of nano-particle size distribution
    In: Sensors Jg. 17 (2017) Nr. 2, S. 244
    ISSN: 1424-8220
    Online Volltext: dx.doi.org/ (Open Access)
  • Lelle, Marco; Freidel, Christoph; Kaloyanova, Stefka; Tabujew, Ilja; Schramm, Alexander; Musheev, Michael; Niehrs, Christof; Müllen, Klaus; Peneva, Kalina
    Overcoming drug resistance by cell-penetrating peptide-mediated delivery of a doxorubicin dimer with high DNA-binding affinity
    In: European Journal of Medicinal Chemistry Jg. 130 (2017) S. 336 - 345
    ISSN: 1768-3254; 0223-5234
    Online Volltext: dx.doi.org/
  • Schwermer, Melanie; Dreesmann, Sabine; Eggert, Angelika; Althoff, Kristina; Steenpass, Laura; Schramm, Alexander; Schulte, Johannes; Temming, Petra
    Pharmaceutically inhibiting polo-like kinase 1 exerts a broad anti-tumour activity in retinoblastoma cell lines
    In: Clinical & Experimental Ophthalmology Jg. 45 (2017) Nr. 3, S. 288 - 296
    ISSN: 1442-9071; 1442-6404
    Online Volltext: dx.doi.org/
  • Gottlieb, Aline; Althoff, Kristina; Grunewald, Laura; Thor, Theresa; Odersky, Andrea; Schulte, Marc; Deubzer, Hedwig E.; Heukamp, Lukas; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes; Künkele, Annette
    RITA displays anti-tumor activity in medulloblastomas independent of TP53 status
    In: OncoTarget Jg. 8 (2017) Nr. 17, S. 27882 - 27891
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/ (Open Access)
  • Henssen, Anton G; Odersky, Andrea; Szymansky, Annabell; Seiler, Marleen; Althoff, Kristina; Beckers, Anneleen; Speleman, Frank; Schäfers, Simon; De Preter, Katleen; Astrahanseff, Kathy; Struck, Joachim; Schramm, Alexander; Eggert, Angelika; Bergmann, Andreas; Schulte, Johannes
    Targeting tachykinin receptors in neuroblastoma
    In: OncoTarget Jg. 8 (2017) Nr. 1, S. 430 - 443
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/ (Open Access)
  • Pajtler, Kristian; Sadowski, Natalie; Ackermann, Sandra; Althoff, Kristina; Schönbeck, Kerstin; Batzke, Katharina; Schäfers, Simon; Odersky, Andrea; Heukamp, Lukas; Astrahantseff, Kathy; Künkele, Annette; Deubzer, Hedwig E; Schramm, Alexander; Sprüssel, Annika; Thor, Theresa; Lindner, Sven; Eggert, Angelika; Fischer, Matthias; Schulte, Johannes
    The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models
    In: OncoTarget Jg. 8 (2017) Nr. 4, S. 6730 - 6741
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/ (Open Access)
  • Fielitz, Kathrin; Althoff, Kristina; De Preter, Katleen; Nonnekens, Julie; Ohli, Jasmin; Elges, Sandra; Hartmann, Wolfgang; Klöppel, Günter; Knösel, Thomas; Schulte, Marc; Klein-Hitpaß, Ludger; Beisser, Daniela; Reis, Henning; Eyking, Annette; Cario, Elke; Schulte, Johannes; Schramm, Alexander; Schüller, Ulrich
    Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells
    In: OncoTarget Jg. 7 (2016) Nr. 46, S. 74415 - 74426
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/ (Open Access)
  • Müller, Jan; Reichel, Robin; Müller, Stefan; Sauerwein, Wolfgang; Brandau, Wolfgang; Eggert, Angelika; Schramm, Alexander
    Identification and Tumour-Binding Properties of a Peptide with High Affinity to the Disialoganglioside GD2
    In: PLoS ONE Jg. 11 (2016) Nr. 10, S. e0163648
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Büchel, Gabriele; Schulte, Johannes; Harrison, Luke; Batzke, Katharina; Schüller, Ulrich; Hansen, Wiebke; Schramm, Alexander
    Immune response modulation by Galectin-1 in a transgenic model of neuroblastoma
    In: OncoImmunology Jg. 5 (2016) Nr. 5, S. e1131378
    ISSN: 2162-4011; 2162-402X
    Online Volltext: dx.doi.org/ (Open Access)
  • Schramm, Alexander; Lode, Holger
    MYCN-targeting vaccines and immunotherapeutics
    In: Human Vaccines & Immunotherapeutics Jg. 12 (2016) Nr. 9, S. 2257 - 2258
    ISSN: 2164-554X; 2164-5515; 1554-8619; 1554-8600
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Henssen, Anton; Althoff, Kristina; Odersky, Andrea; Beckers, Anneleen; Koche, Richard; Speleman, Frank; Schäfers, Simon; Bell, Emma; Nortmeyer, Maike; Westermann, Frank; De Preter, Katleen; Florin, Alexandra; Heukamp, Lukas; Spruessel, Annika; Astrahanseff, Kathy; Lindner, Sven; Sadowski, Natalie; Schramm, Alexander; Astorgues-Xerri, Lucile; Riveiro, Maria E.; Eggert, Angelika; Cvitkovic, Esteban; Schulte, Johannes
    Targeting MYCN-driven transcription by BET-bromodomain inhibition
    In: Clinical Cancer Research Jg. 22 (2016) Nr. 10, S. 2470 - 2781
    ISSN: 1557-3265; 1078-0432
    Online Volltext: dx.doi.org/ (Open Access)
  • Riehl, Lara M; Schulte, Johannes; Mulaw, Medhanie A; Dahlhaus, Meike; Fischer, Matthias; Schramm, Alexander; Eggert, Angelika; Debatin, Klaus-Michael; Beltinger, Christian
    The mitochondrial genetic landscape in neuroblastoma from tumor initiation to relapse
    In: OncoTarget Jg. 7 (2016) Nr. 6, S. 6620 - 6625
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/ (Open Access)
  • Althoff, Kristina; Schulte, Johannes H.; Schramm, Alexander
    Towards diagnostic application of non-coding RNAs in neuroblastoma
    In: Expert Review of Molecular Diagnostics Jg. 16 (2016) Nr. 12, S. 1307 - 1313
    ISSN: 1473-7159; 1473-7159
    Online Volltext: dx.doi.org/
  • Althoff, K; Beckers, A; Bell, E; Nortmeyer, M; Thor, T; Sprüssel, A; Lindner, S; De Preter, K; Florin, A; Heukamp, L C; Klein-Hitpaß, Ludger; Astrahantseff, K; Kumps, C; Speleman, F; Eggert, A; Westermann, F; Schramm, Alexander; Schulte, Johannes
    A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies
    In: Oncogene Jg. 34 (2015) Nr. 26, S. 3357 - 3368
    ISSN: 0950-9232; 1476-5594
    Online Volltext: dx.doi.org/ (Open Access)
  • Lindner, Sven; Bachmann, Hagen Sjard; Odersky, Andrea; Schaefers, Simon; Klein-Hitpaß, Ludger; Hero, Barbara; Fischer, Matthias; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes
    Absence of telomerase reverse transcriptase promoter mutations in neuroblastoma
    In: Biomedical Reports Jg. 3 (2015) Nr. 4, S. 443 - 446
    ISSN: 2162-4178; 2049-9442
    Online Volltext: dx.doi.org/
  • Stephan, Harald; Menke, Katrin; Felenda, Jennifer; Zuzak, Tycho J.; Schramm, Alexander; Beckmann, Christiane; Stintzing, Florian
    Dandelion (Taraxacum officinale) extracts supply antitumour effects of mistletoe in pediatric cancer cells
    In: Phytomedicine Jg. 22 (2015) Nr. Suppl.1, S. S25 - S26
    ISSN: 0944-7113
    Online Volltext: dx.doi.org/
  • Eggert, Angelika; Schramm, Alexander; Koester, J.; Assenov, Y.; Kristina, A.; Engesser, A.; Kahlert, Y.; Theissen, J.; Hero, B.; Roels, F.; Peifer, M.; Astrahantseff, K.; Depreter, K.; Lode, H.; Speleman, F.; Schmezer, P.; Westermann, F.; Rahmann, Sven; Fischer, Markus; Schulte, Johannes
    INTEGRATED GENOMIC ANALYSIS IDENTIFIES SPECIFIC ALTERATIONS AND ACTIVATION OF YAP IN RELAPSED NEUROBLASTOMA
    In: Pediatric Blood and Cancer Jg. 62 4 (2015) S. S145 - S145
    ISSN: 1545-5009; 1545-5017
  • Thor, Theresa; Künkele, Annette; Pajtler, Kristian; Wefers, Annika K; Stephan, Harald; Mestdagh, Pieter; Heukamp, Lukas; Hartmann, Wolfgang; Vandesompele, Jo; Sadowski, Natalie; Becker, Lore; Garrett, Lillian; Hölter, Sabine M; Horsch, Marion; Calzada-Wack, Julia; Klein-Rodewald, Tanja; Racz, Ildiko; Zimmer, Andreas; Beckers, Johannes; Neff, Frauke; Klopstock, Thomas; De Antonellis, Pasqualino; Zollo, Massimo; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valérie; Schüller, Ulrich; de Angelis, Martin Hrab?; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes
    MiR-34a deficiency accelerates medulloblastoma formation in vivo
    In: International Journal of Cancer Jg. 136 (2015) Nr. 10, S. 2293 - 2303
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/ (Open Access)
  • Schramm, Alexander; Köster, Johannes; Assenov, Yassen; Althoff, Kristina; Peifer, Martin; Mahlow, Ellen; Odersky, Andrea; Beisser, Daniela; Ernst, Corinna; Henssen, Anton G; Stephan, Harald; Schröder, Christopher; Heukamp, Lukas; Engesser, Anne; Kahlert, Yvonne; Theissen, Jessica; Hero, Barbara; Roels, Frederik; Altmüller, Janine; Nürnberg, Peter; Astrahantseff, Kathy; Gloeckner, Christian; De Preter, Katleen; Plass, Christoph; Lee, Sangkyun; Lode, Holger N; Henrich, Kai-Oliver; Gartlgruber, Moritz; Speleman, Frank; Schmezer, Peter; Westermann, Frank; Rahmann, Sven; Fischer, Matthias; Eggert, Angelika; Schulte, Johannes
    Mutational dynamics between primary and relapse neuroblastomas
    In: Nature Genetics Jg. 47 (2015) Nr. 8, S. 872 - 877
    ISSN: 1061-4036; 1546-1718
    Online Volltext: dx.doi.org/
  • Schwermer, Melanie; Lee, Sangkyun; Köster, Johannes; van Maerken, Tom; Stephan, Harald; Eggert, Angelika; Morik, Katharina; Schulte, Johannes; Schramm, Alexander
    Sensitivity to cdk1-inhibition is modulated by p53 status in preclinical models of embryonal tumors
    In: OncoTarget Jg. 6 (2015) Nr. 17, S. 15425 - 15435
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/ (Open Access)
  • Stermann, Alexander; Huebener, Nicole; Seidel, Diana; Fest, Stefan; Eschenburg, Georg; Stauder, Michael; Schramm, Alexander; Eggert, Angelika; Lode, Holger N
    Targeting of MYCN by means of DNA vaccination is effective against neuroblastoma in mice
    In: Cancer Immunology, Immunotherapy Jg. 64 (2015) Nr. 10, S. 1215 - 1227
    ISSN: 0340-7004; 1432-0851
    Online Volltext: dx.doi.org/
  • Spruessel, Annika; Schäfers, Simon; De Preter, Katleen; Sadowski, Natalie; Eggert, Angelika; Florin, Alexandra; Schramm, Alexander; Astorgues-Xerri, Lucile; Beckers, Anneleen; Odersky, Andrea; Heukamp, Lukas; Althoff, Kristina; Riveiro, Eugenia; Astrahanseff, Kathy; Koche, Richard; Cvitkovic, Esteban; Speleman, Frank; Henssen, Anton; Schulte, Johannes
    Targeting super-enhancer induced gene expression with the novel BRD4 inhibitor OTX015 in preclinical models of MYCN-amplified neuroblastoma
    In: Cancer Research Jg. 75 (2015) Nr. 15 Suppl., S. 4731
    ISSN: 0008-5472; 0008-5472
    Online Volltext: dx.doi.org/
  • Peifer, Martin; Hertwig, Falk; Roels, Frederik; Dreidax, Daniel; Gartlgruber, Moritz; Menon, Roopika; Krämer, Andrea; Roncaioli, Justin L; Sand, Frederik; Heuckmann, Johannes M; Ikram, Fakhera; Schmidt, Rene; Ackermann, Sandra; Engesser, Anne; Kahlert, Yvonne; Vogel, Wenzel; Altmüller, Janine; Nürnberg, Peter; Thierry-Mieg, Jean; Thierry-Mieg, Danielle; Mariappan, Aruljothi; Heynck, Stefanie; Mariotti, Erika; Henrich, Kai-Oliver; Gloeckner, Christian; Bosco, Graziella; Leuschner, Ivo; Schweiger, Michal R; Savelyeva, Larissa; Watkins, Simon C; Shao, Chunxuan; Bell, Emma; Höfer, Thomas; Achter, Viktor; Lang, Ulrich; Theissen, Jessica; Volland, Ruth; Saadati, Maral; Eggert, Angelika; de Wilde, Bram; Berthold, Frank; Peng, Zhiyu; Zhao, Chen; Shi, Leming; Ortmann, Monika; Büttner, Reinhard; Perner, Sven; Hero, Barbara; Schramm, Alexander; Schulte, Johannes; Herrmann, Carl; O'Sullivan, Roderick J; Westermann, Frank; Thomas, Roman K; Fischer, Matthias
    Telomerase activation by genomic rearrangements in high-risk neuroblastoma
    In: Nature Jg. 526 (2015) Nr. 7575, S. 700 - 704
    ISSN: 0028-0836; 1476-4687
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Kraemer, Andrea; Hertwig, Falk; Thomas, Roman K.; Buettner, Reinhard; Westermann, Frank; Perner, Sven; Fischer, Matthias; Schramm, Alexander; Menon, Roopika; Schulte, Johannes; Peifer, Martin; Roels, Frederik
    Telomerase activation by genomic rearrangements in high-risk neuroblastoma
    In: Cancer Research Jg. 75 (2015) Nr. 15 Suppl., S. LB - 210
    ISSN: 0008-5472
    Online Volltext: dx.doi.org/
  • Thiele, Oliver C.; Brom, Jörn; Dunsche, Anton; Ehrenfeld, Michael; Federspil, Philipp; Frerich, Bernhard; Hölzle, Frank; Klein, Martin; Kreppel, Matthias; Kübler, Alexander C.; Kübler, Norbert R.; Kunkel, Martin; Kuttenberger, Johannes; Lauer, Günter; Mayer, Boris; Mohr, Christopher; Neff, Andreas; Rasse, Michael; Reich, Rudolf H.; Reinert, Sigmar; Rothamel, Daniel; Sader, Robert; Schliephake, Henning; Schmelzeisen, Rainer; Schramm, Alexander; Sieg, Peter; Terheyden, Hendrik; Wiltfang, Jörg; Ziegler, Christoph M.; Mischkowski, Robert A.; Zöller, Joachim E.
    The current state of facial prosthetics : A multicenter analysis
    In: Journal of Oral and Maxillofacial Surgery Jg. 43 (2015) Nr. 7, S. 1038 - 1041
    ISSN: 1531-5053; 1010-5182; 0301-0503
    Online Volltext: dx.doi.org/
  • Althoff, Kristina; Lindner, Sven; Odersky, Andrea; Mestdagh, Pieter; Beckers, Anneleen; Karczewski (ehem.Tillmann), Sarah; Molenaar, Jan J; Bohrer, Anna; Knauer, Shirley; Speleman, Frank; Epple, Matthias; Kozlova, Diana; Yoon, Sena; Baek, Kwanghee; Vandesompele, Jo; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes
    miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin
    In: International Journal of Cancer Jg. 136 (2015) Nr. 6, S. 1308 - 1320
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/ (Open Access)
  • Pajtler, Kristian; Mahlow, Ellen; Odersky, Andrea; Lindner, Sven; Stephan, Harald; Bendix, Ivo; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes
    Neuroblastoma in dialog with its stroma : NTRK1 is a regulator of cellular cross-talk with Schwann cells
    In: OncoTarget Jg. 5 (2014) Nr. 22, S. 11180 - 11192
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/ (Open Access)
  • Lee, Sangkyun; Rahnenführer, Jörg; Lang, Michel; De Preter, Katleen; Mestdagh, Pieter; Koster, Jan; Versteeg, Rogier; Stallings, Raymond L; Varesio, Luigi; Asgharzadeh, Shahab; Schulte, Johannes; Fielitz, Kathrin; Schwermer, Melanie; Morik, Katharina; Schramm, Alexander
    Robust selection of cancer survival signatures from high-throughput genomic data using two-fold subsampling
    In: PLoS ONE Jg. 9 (2014) Nr. 10, S. e108818
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ (Open Access)
  • Henssen, Anton; Thor, Theresa; Odersky, Andrea; Heukamp, Lukas; El-Hindy, Nicolai; Beckers, Anneleen; Speleman, Frank; Althoff, Kristina; Schäfers, Simon; Schramm, Alexander; Sure, Ulrich; Fleischhack, Gudrun; Eggert, Angelika; Schulte, Johannes
    BET bromodomain protein inhibition is a therapeutic option for medulloblastoma
    In: OncoTarget Jg. 4 (2013) Nr. 11, S. 2080 - 2095
    ISSN: 1949-2553
    Online Volltext: dx.doi.org/
  • Grum, Daniel; Franke, Stefan; Kraff, Oliver; Heider, Dominik; Schramm, Alexander; Hoffmann, Daniel; Bayer, Peter
    Design of a Modular Protein-Based MRI Contrast Agent for Targeted Application
    In: PLoS ONE Jg. 8 (2013) Nr. 6, S. e65346
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Leitão, Andrei; Schramm, Alexander; Eggert, Angelika
    Discovery of a new bioactive molecule for neuroblastoma
    In: Chemical Biology and Drug Design Jg. 82 (2013) Nr. 2, S. 233 - 241
    ISSN: 1747-0277; 1747-0285; 1397-002X; 1399-3011
    Online Volltext: dx.doi.org/
  • Pajtler, Kristian; Rebmann, Vera; Lindemann, Monika; Schulte, Johannes; Schulte, Stefanie; Stauder, Michael; Leuschner, Ivo; Schmid, Kurt Werner; Köhl, Ulrike; Schramm, Alexander; Eggert, Angelika
    Expression of NTRK1/TrkA affects immunogenicity of neuroblastoma cells
    In: International Journal of Cancer Jg. 133 (2013) Nr. 4, S. 908 - 919
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Kumps, Candy; Fieuw, Annelies; Mestdagh, Pieter; Menten, Björn; Lefever, Steve; Pattyn, Filip; De Brouwer, Sara; Sante, Tom; Schulte, Johannes; Schramm, Alexander; Van Roy, Nadine; Van Maerken, Tom; Noguera, Rosa; Combaret, Valérie; Devalck, Christine; Westermann, Frank; Laureys, Geneviève; Eggert, Angelika; Vandesompele, Jo; De Preter, Katleen; Speleman, Frank
    Focal DNA copy number changes in neuroblastoma target MYCN regulated genes
    In: PLoS ONE Jg. 8 (2013) Nr. 1, S. e52321
    ISSN: 1932-6203
    Online Volltext: dx.doi.org/ (Open Access)
  • Rahmann, Sven; Martin, Marcel; Schulte, Johannes; Köster, Johannes; Marschall, Tobias; Schramm, Alexander
    Identifying transcriptional miRNA biomarkers by integrating high-throughput sequencing and real-time PCR data
    In: Methods: A Companion to Methods in Enzymology Jg. 59 (2013) Nr. 1, S. 154 - 163
    ISSN: 1095-9130; 1046-2023
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Molenaar, J.; Lindner, S.; Schramm, Alexander; Mestdagh, P.; Speleman, F.; Versteeg, R.; Eggert, Angelika
    LIN28B drives neuroblastoma oncogenesis through let7-MYCN signaling
    In: Cancer Research Jg. 73 (2013) Nr. 8 Suppl. 1, S. 4596
    ISSN: 0008-5472; 1538-7445; 0099-7013; 0099-7374
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Lindner, Sven; Bohrer, Anna Margarethe; Maurer, J.; De Preter, Katleen D.; Lefever, Steve; Heukamp, Lukas Carl; Schulte, Stefanie; Molenaar, Jan J.; Versteeg, Rogier; Thor, Theresa; Künkele, Annette; Vandesompele, Jo O.; Speleman, Frank P.; Schorle, Hubert; Eggert, Angelika; Schramm, Alexander
    MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells
    In: Oncogene Jg. 32 (2013) Nr. 8, S. 1059 - 1065
    ISSN: 1476-5594; 0950-9232
    Online Volltext: dx.doi.org/
  • Althoff, Kristina; Beckers, Anneleen; Odersky, Andrea; Mestdagh, Pieter; Köster, Johannes; Bray, Isabella M; Bryan, Kenneth; Vandesompele, Jo; Speleman, Frank; Stallings, Raymond L; Schramm, Alexander; Eggert, Angelika; Sprüssel, Annika; Schulte, Johannes H.
    MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A
    In: International Journal of Cancer Jg. 133 (2013) Nr. 5, S. 1064 - 1073
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Das, S.; Bryan, K.; Buckley, P. G.; Piskareva, O.; Bray, I. M.; Foley, N.; Ryan, J.; Lynch, J.; Creevey, L.; Fay, J.; Prenter, S.; Koster, J.; van Sluis, P.; Versteeg, R.; Eggert, Angelika; Schulte, Johannes; Schramm, Alexander; Mestdagh, P.; Vandesompele, J.; Speleman, F.; Stallings, R. L.
    Modulation of neuroblastoma disease pathogenesis by an extensive network of epigenetically regulated microRNAs
    In: Oncogene Jg. 32 (2013) Nr. 24, S. 2927 - 2936
    ISSN: 0950-9232; 1476-5594
    Online Volltext: dx.doi.org/
  • Carotenuto, Marianeve; Pedone, Emilia; Diana, Donatella; De Antonellis, Pasqualino; Džeroski, Sašo; Marino, Natascia; Navas, Luigi; Di Dato, Valeria; Scoppettuolo, Maria Nunzia; Cimmino, Flora; Correale, Stefania; Pirone, Luciano; Monti, Simona Maria; Bruder, Elisabeth; Ženko, Bernard; Slavkov, Ivica; Pastorino, Fabio; Ponzoni, Mirco; Schulte, Johannes; Schramm, Alexander; Eggert, Angelika; Westermann, Frank; Arrigoni, Gianluigi; Accordi, Benedetta; Basso, Giuseppe; Saviano, Michele; Fattorusso, Roberto; Zollo, Massimo
    Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction
    In: Scientific Reports Jg. 3 (2013) S. 1351
    ISSN: 2045-2322
    Online Volltext: dx.doi.org/ (Open Access)
  • Schramm, Alexander; Köster, Johannes; Marschall, Tobias; Martin, Marcel; Schwermer, Melanie; Fielitz, Kathrin; Büchel, Gabriele; Barann, Matthias; Esser, Daniela; Rosenstiel, Philip; Rahmann, Sven; Eggert, Angelika; Schulte, Johannes
    Next-generation RNA sequencing reveals differential expression of MYCN target genes and suggests the mTOR pathway as a promising therapy target in MYCN-amplified neuroblastoma
    In: International Journal of Cancer Jg. 132 (2013) Nr. 3, S. E106 - E115
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Schulte, S; Heukamp, L C; Astrahantseff, K; Stephan, H; Fischer, M; Schramm, Alexander; Eggert, Angelika
    Targeted Therapy for Neuroblastoma : ALK Inhibitors
    In: Klinische Pädiatrie Jg. 225 (2013) Nr. 6, S. 303 - 308
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Muller, J.; Vogt, S.; Reichel, R.; Fielitz, K.; Muller, S.; Brandau, W.; Schramm, Alexander
    Targeting the disialoganglioside GD2 in neuroblastoma using a phage display derived oligopeptide
    In: European Journal of Nuclear Medicine and Molecular Imaging Jg. 40 (2013) Nr. Suppl 2, S. S295
    ISSN: 1619-7070; 1619-7089; 0340-6997; 1432-105X
    Online Volltext: dx.doi.org/
  • Künkele, Annette; Grosse-Lordemann, Anja; Schramm, Alexander; Eggert, Angelika; Schulte, Johannes; Bachmann, Hagen Sjard
    The BCL2-938 C > A promoter polymorphism is associated with risk group classification in children with acute lymphoblastic leukemia
    In: BMC Cancer Jg. 13 (2013) S. 452
    ISSN: 1471-2407
    Online Volltext: dx.doi.org/ (Open Access)
  • Pajtler, Kristian W.; Weingarten, Christina; Thor, Theresa; Künkele, Annette; Heukamp, Lukas C.; Büttner, Reinhard; Suzuki, Takayoshi; Miyata, Naoki; Grotzer, Michael; Rieb, Anja; Sprüssel, Annika; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes
    The KDM1A histone demethylase is a promising new target for the epigenetic therapy of medulloblastoma
    In: Acta Neuropathologica Communications Jg. 1 (2013) Nr. 1, S. 19
    ISSN: 2051-5960
    Online Volltext: dx.doi.org/ (Open Access)
  • Cornero, Andrea; Acquaviva, Massimo; Fardin, Paolo; Versteeg, Rogier; Schramm, Alexander; Eva, Alessandra; Bosco, Maria Carla; Blengio, Fabiola; Barzaghi, Sara; Varesio, Luigi
    Design of a multi-signature ensemble classifier predicting neuroblastoma patients' outcome
    In: BMC Bioinformatics Jg. 13 (2012) Nr. Suppl 4, S. 13
    ISSN: 1471-2105
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • De Brouwer, Sara; Mestdagh, Pieter; Lambertz, Irina; Pattyn, Filip; De Paepe, Anne; Westermann, Frank; Schroeder, Christina; Schulte, Johannes; Schramm, Alexander; De Preter, Katleen; Vandesompele, Jo; Speleman, Frank
    Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma
    In: International Journal of Cancer Jg. 130 (2012) Nr. 11, S. 2591 - 2598
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Schramm, Alexander; Schowe, Benjamin; Fielitz, Kathrin; Heilmann, Mareike N.; Martin, Marcel; Marschall, Tobias; Köster, Johannes; Vandesompele, Jo; Vermeulen, Joëlle; de Preter, Katleen D.; Koster, Jan; Versteeg, Rogier; Noguera, Rosa; Speleman, Frank P.; Rahmann, Sven; Eggert, Angelika; Morik, Katharina J.; Schulte, Johannes
    Exon-level expression analyses identify MYCN and NTRK1 as major determinants of alternative exon usage and robustly predict primary neuroblastoma outcome
    In: British Journal of Cancer (BJC) Jg. 107 (2012) Nr. 8, S. 1409 - 1417
    ISSN: 1532-1827; 0007-0920
    Online Volltext: dx.doi.org/ (Open Access)
  • Schramm, Alexander; Eggert, Angelika; Rahmann, Sven
    Genen auf der Spur : wie genomweite Analysen am Modell Neuroblastom zukünftige Therapiemöglichkeiten aufzeigen
    In: Unikate: Berichte aus Forschung und Lehre (2012) Nr. 42: Translationale Krebsforschung: Auf dem Weg zu neuen Therapien, S. 22 - 31
    ISBN: 978-3-934359-42-0 ISSN: 0944-6060; 1869-3881
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Fieuw, Annelies; Kumps, Candy; Schramm, Alexander; Pattyn, Filip; Menten, Björn; Antonacci, Francesca; Sudmant, Peter; Schulte, Johannes; Van Roy, Nadine; Vergult, Sarah; Buckley, Patrick G.; De Paepe, Anne M.; Noguera, Rosa; Versteeg, Rogier; Stallings, Raymond; Eggert, Angelika; Vandesompele, Jo; De Preter, Katleen D.; Speleman, Frank
    Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomas
    In: International Journal of Cancer Jg. 130 (2012) Nr. 11, S. 2599 - 2606
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Lindner, S.; Molenaar, J.; Thor, T.; Spruessel, A.; Caron, H N; Versteeg, R.; Schramm, Alexander; Eggert, Angelika; Schulte, Johannes
    LIN28B drives neuroblastoma oncogenesis through let7-MYCN signaling
    In: Klinische Pädiatrie Jg. 224 (2012) S. 222
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Molenaar, Jan J.; Domingo-Fernández, Raquel; Ebus, Marli E.; Lindner, Sven; Koster, Jan; Drabek, Ksenija; Mestdagh, Pieter; Van Sluis, Peter; Valentijn, Linda J.; Van Nes, Johan; Broekmans, Marloes; Haneveld, Franciska; Volckmann, Richard; Bray, Isabella; Heukamp, Lukas; Sprüssel, Annika; Thor, Theresa; Kieckbusch, Kristina; Klein-Hitpaß, Ludger; Fischer, Matthias; Vandesompele, Jo; Schramm, Alexander; Van Noesel, Max M.; Varesio, Luigi; Speleman, Frank; Eggert, Angelika; Stallings, Raymond L.; Caron, Huib N.; Versteeg, Rogier; Schulte, Johannes
    LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression
    In: Nature Genetics Jg. 44 (2012) Nr. 11, S. 1199 - 1206
    ISSN: 1061-4036; 1546-1718
    Online Volltext: dx.doi.org/
  • Sprüssel, Annika; Schulte, Johannes; Weber, Stefanie; Necke, M.; Händschke, K.; Thor, Theresa; Pajtler, Kristian; Schramm, Alexander; König, Katharina; Diehl, Linda; Mestdagh, Pieter; Vandesompele, Jo; Speleman, Frank P.; Jastrow, Holger; Heukamp, Lukas Carl; Schüle, Roland; Dührsen, Ulrich; Buettner, Reinhard H.; Eggert, Angelika; Göthert, Joachim Rudolf
    Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation
    In: Leukemia Jg. 26 (2012) Nr. 9, S. 2039 - 2051
    ISSN: 0887-6924; 1476-5551
    Online Volltext: dx.doi.org/
  • Künkele, Annette; De Preter, Katleen; Heukamp, Lukas; Thor, Theresa; Pajtler, Kristian; Hartmann, Wolfgang; Mittelbronn, Michel; Grotzer, Michael A.; Deubzer, Hedwig E.; Speleman, Frank; Schramm, Alexander; Eggert, Angelika; Schulte, Johannes
    Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas
    In: Neuro-Oncology Jg. 14 (2012) Nr. 7, S. 859 - 869
    ISSN: 1522-8517; 1523-5866
    Online Volltext: dx.doi.org/ (Open Access)
  • Gottlieb, A.; Kuenkele, A.; Schramm, Alexander; Eggert, Angelika; Schulte, Johannes
    RITA-p53 activation in medulloblastoma as a new approach for treatment?
    In: Klinische Pädiatrie Jg. 224 (2012) S. 221
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Eschenburg, Georg; Eggert, Angelika; Schramm, Alexander; Lode, Holger N.; Hundsdoerfer, Patrick
    Smac mimetic LBW242 sensitizes XIAP-overexpressing neuroblastoma cells for TNF-α-independent apoptosis
    In: Cancer Research Jg. 72 (2012) Nr. 10, S. 2645 - 2656
    ISSN: 0008-5472; 1538-7445; 0099-7013; 0099-7374
    Online Volltext: dx.doi.org/ (Open Access)
  • Nittner, David; Lambertz, Irina; Clermont, Frederic; Mestdagh, Pieter; Köhler, Corinna; Nielsen, Soren Jensby; Jochemsen, Aart; Speleman, Frank; Vandesompele, Jo; Dyer, Michael A.; Schramm, Alexander; Schulte, Johannes; Marine, Jean-Christophe
    Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation
    In: Nature Cell Biology Jg. 14 (2012) Nr. 9, S. 958 - 965
    ISSN: 1465-7392; 1476-4679
    Online Volltext: dx.doi.org/
  • Heukamp, Lukas C.; Thor, Theresa; Schramm, Alexander; De Preter, Katleen; Kumps, Candy; De Wilde, Bram; Odersky, Andrea; Peifer, Martin; Lindner, Sven; Spruessel, Annika; Pattyn, Filip; Mestdagh, Pieter; Menten, Bjoern; Kuhfittig-Kulle, Steffi; Künkele, Annette; König, Katharina; Meder, Lydia; Chatterjee, Sampurna; Ullrich, Roland T.; Schulte, Stefanie; Vandesompele, Jo; Speleman, Frank; Büttner, Reinhard; Eggert, Angelika; Schulte, Johannes
    Targeted expression of mutated ALK induces neuroblastoma in transgenic mice
    In: Science Translational Medicine Jg. 4 (2012) Nr. 141, S. 141ra91
    ISSN: 1946-6234; 1946-6242
    Online Volltext: dx.doi.org/
  • Fielitz, K.; Schowe, B.; Schulte, Johannes; Vandesompele, J.; Mestdagh, P.; Eggert, Angelika; Morik, K.; Schramm, Alexander
    The JARID 1C histone demethylase is upregulated in aggressive neuroblastomas independent of MYCN amplification
    In: Klinische Pädiatrie Jg. 224 (2012) S. 221 - 222
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Liguori, Lucia; Andolfo, Immacolata; De Antonellis, Pasqualino; Aglio, Veruska; Di Dato, Valeria; Marino, Natascia; Orlotti, Nicola Ivan; De Martino, Daniela; Capasso, Mario; Petrosino, Giuseppe; Schramm, Alexander; Navas, Luigi; Tonini, Gian Paolo; Eggert, Angelika; Iolascon, Achille; Zollo, Massimo
    The metallophosphodiesterase Mpped2 impairs tumorigenesis in neuroblastoma
    In: Cell Cycle Jg. 11 (2012) Nr. 3, S. 569 - 581
    ISSN: 1554-8627; 1538-4101
    Online Volltext: dx.doi.org/
  • Fiaschetti, G.; Castelletti, D.; Zoller, S.; Schramm, Alexander; Schroeder, C.; Nagaishi, M.; Stearns, D.; Mittelbronn, M.; Eggert, Angelika; Westermann, F.; Ohgaki, H.; Shalaby, T.; Pruschy, M.; Arcaro, A.; Grotzer, M. A.
    Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma
    In: Oncogene Jg. 30 (2011) Nr. 25, S. 2823 - 2835
    ISSN: 0950-9232; 1476-5594
    Online Volltext: dx.doi.org/
  • Esser, R.; Glienke, W.; Bochennek, K.; Erben, S.; Quaiser, A.; Pieper, C.; Eggert, Angelika; Schramm, Alexander; Astrahantseff, K.; Hansmann, M. L.; Schwabe, D.; Klingebiel, T.; Koehl, U.
    Detection of neuroblastoma cells during clinical follow up : advanced flow cytometry and rt-PCR for tyrosine hydroxylase using both conventional and real-time PCR
    In: Klinische Pädiatrie Jg. 223 (2011) Nr. 6, S. 326 - 331
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Bachmann, Hagen Sjard; Brockmeyer, Bent; DePreter, Katleen; Oberthuer, Andre; Ackermann, Sandra; Kahlert, Yvonne; Pajtler, Kristian; Theissen, Jessica; Westermann, Frank; Vandesompele, J. o.; Speleman, Frank; Berthold, Frank; Eggert, Angelika; Brors, Benedikt; Hero, Barbara; Schramm, Alexander; Fischer, Matthias
    High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation as a Determining Factor of an Unfavorable Phenotype in Primary Neuroblastoma
    In: Clinical Cancer Research Jg. 17 (2011) Nr. 15, S. 5082 - 5092
    ISSN: 1078-0432; 1557-3265
    Online Volltext: dx.doi.org/
  • Eggert, Angelika; Schulte, Johannes; Astrahantseff, K.; Pajtler, Kristian; Kunkele, A.; Schramm, Alexander
    Molecular Targets in Embryonal Tumors
    In: Klinische Pädiatrie Jg. 223 (2011) Nr. 1, S. 48
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Kunkele, A.; de Preter, K.; Vandesompele, J.; Thor, T.; Pajtler, Kristian; Hartmann, W.; Heukamp, L.; Schramm, Alexander; Eggert, Angelika; Schulte, Johannes
    Pharmacological activation of the p53 pathway by nutlin-3 inhibits medulloblastoma cell proliferation in vitro and in vivo
    In: European Journal of Pediatrics Jg. 170 (2011) Nr. 2, S. 267 - 268
    ISSN: 0340-6199; 1432-1076
    Online Volltext: dx.doi.org/
  • Ackermann, Sandra; Goeser, Felix; Schulte, Johannes; Schramm, Alexander; Ehemann, Felix; Hero, Barbara; Eggert, Angelika; Berthold, Frank; Fischer, Matthias
    Polo-like kinase 1 is a therapeutic target in high-risk neuroblastoma
    In: Clinical Cancer Research Jg. 17 (2011) Nr. 4, S. 731 - 741
    ISSN: 1078-0432; 1557-3265
    Online Volltext: dx.doi.org/
  • Bachmann, Hagen Sjard; Heukamp, Lucas C.; Schmitz, Klaus Jürgen; Hilburn, Caroline F.; Kahl, Philip; Buettner, Reinhard; Nückel, Holger; Eisenhardt, Andreas; Rübben, Herbert; Schmid, Kurt Werner; Siffert, Winfried; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes
    Regulatory BCL2 promoter polymorphism (-938C>A) is associated with adverse outcome in patients with prostate carcinoma
    In: International Journal of Cancer Jg. 129 (2011) Nr. 10, S. 2390 - 2399
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Zuzak, T. J.; Bornschein, M.; Stephan, H.; Pajtler, Kristian; Eisenbraun, J.; Schramm, Alexander; Eggert, Angelika
    Viscum Album (mistletoe) extract inhibits growth of pediatric tumor cells in vitro
    In: Klinische Pädiatrie Jg. 223 (2011) Nr. 3, S. 198
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Zuzak, T. J.; Bornschein, M.; Menke, Katharina; Stephan, H.; Pajtler, Kristian; Eisenbraun, J.; Schramm, Alexander
    Viscum album inhibits cell growth, migration and invasion of pediatric tumor cell lines - But effects are limited at concentrations found in serum
    In: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology Jg. 18 (2011) Nr. Suppl. 8, S. 8 - S9
    ISSN: 0944-7113; 1618-095X
    Online Volltext: dx.doi.org/
  • De Preter, K.; Mestdagh, P.; Vermeulen, J.; Zeka, F.; Naranjo, A.; Bray, I.; Castel, V.; Chen, C.; Drozynska, E.; Eggert, Angelika; Hogarty, M. D.; Izycka-Swieszewska, E.; London, W. B.; Noguera, R.; Piqueras, M.; Bryan, K.; Schowe, B.; van Sluis, P.; Molenaar, J. J.; Schramm, Alexander; Schulte, Johannes; Stallings, R. L.; Versteeg, R.; Laureys, G.; Van Roy, N.; Speleman, F.; Vandesompele, J.
    miRNA expression profiling enables risk stratification in archived and fresh neuroblastoma tumor samples
    In: Clinical Cancer Research Jg. 17 (2011) Nr. 24, S. 7684 - 7692
    ISSN: 1078-0432; 1557-3265
    Online Volltext: dx.doi.org/
  • Nittner, D.; Lambertz, I.; Schramm, Alexander; Mestdagh, P.; Vandesompele, J.; Dyer, M.A.; Schulte, J.; Marine, J.C.
    384 Dicer1 is a synthetic lethal partner of tumour suppressor p53
    In: European Journal of Cancer / EJC Supplements Jg. 8 (2010) Nr. 5, S. 98
    ISSN: 1878-1217; 1359-6349
    Online Volltext: dx.doi.org/
  • De Preter, Katleen; Vermeulen, Joelle; Brors, Benedikt; Delattre, Olivier; Eggert, Angelika; Fischer, Matthias; Janoueix-Lerosey, Isabelle; Lavarino, Cinzia; Maris, John M.; Mora, Jaume; Nakagawara, Akira; Oberthuer, Andre; Ohira, Miki; Schleiermacher, Gudrun; Schramm, Alexander; Schulte, Johannes; Wang, Qun; Westermann, Frank; Speleman, Frank; Vandesompele, Jo
    Accurate outcome prediction in neuroblastoma across independent data sets using a multigene signature
    In: Clinical Cancer Research Jg. 16 (2010) Nr. 5, S. 1532 - 1541
    ISSN: 1078-0432; 1557-3265
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Schowe, Benjamin; Mestdagh, Pieter; Kaderali, Lars; Kalaghatgi, Prabhav; Schlierf, Stefanie; Vermeulen, Joelle; Brockmeyer, Bent; Pajtler, Kristian; Thor, Theresa; de Preter, Katleen; Speleman, Frank; Morik, Katharina; Eggert, Angelika; Vandesompele, Jo; Schramm, Alexander
    Accurate prediction of neuroblastoma outcome based on miRNA expression profiles
    In: International Journal of Cancer Jg. 127 (2010) Nr. 10, S. 2374 - 2385
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Mestdagh, P.; Fredlund, E.; Pattyn, F.; Rihani, A.; Van Maerken, T.; Vermeulen, J.; Kumps, C.; Menten, B.; De Preter, K.; Schramm, Alexander; Schulte, Johannes; Noguera, R.; Schleiermacher, G.; Janoueix-Lerosey, I.; Laureys, G.; Powel, R.; Nittner, D.; Marine, J. C.; Ringnér, M.; Speleman, F.; Vandesompele, J.
    An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours
    In: Oncogene Jg. 29 (2010) Nr. 24, S. 3583 - 3592
    ISSN: 0950-9232; 1476-5594
    Online Volltext: dx.doi.org/
  • Buckley, Patrick G.; Alcock, Leah; Bryan, Kenneth; Bray, Isabella; Schulte, Johannes; Schramm, Alexander; Eggert, Angelika; Mestdagh, Pieter; De Preter, Katleen; Vandesompele, Jo; Speleman, Frank; Stallings, Raymond L.
    Chromosomal and microRNA expression patterns reveal biologically distinct subgroups of 11q- neuroblastoma
    In: Clinical Cancer Research Jg. 16 (2010) Nr. 11, S. 2971 - 2978
    ISSN: 1078-0432; 1557-3265
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Marschall, Tobias; Martin, Marcel; Rosenstiel, Philipp; Mestdagh, Pieter; Schlierf, Stefanie; Thor, Theresa; Vandesompele, Jo; Eggert, Angelika; Schreiber, Stefan; Rahmann, Sven; Schramm, Alexander
    Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma
    In: Nucleic Acids Research Jg. 38 (2010) Nr. 17, S. 5919 - 5928
    ISSN: 1362-4962; 0301-5610; 0305-1048
    Online Volltext: dx.doi.org/
  • Huenecke, Sabine; Zimmermann, Stefanie Yvonne; Kloess, Stephan; Esser, Ruth; Brinkmann, Andrea; Tramsen, Lars; Koenig, Melanie; Erben, Stephanie; Seidl, Christian; Tonn, Torsten; Eggert, Angelika; Schramm, Alexander; Bader, Peter; Klingebiel, Thomas; Lehrnbecher, Thomas; Passweg, Jakob Robert; Soerensen, Jan; Schwabe, Dirk; Koehl, Ulrike
    IL-2-driven regulation of NK cell receptors with regard to the distribution of CD16+ and CD16- subpopulations and in vivo influence after haploidentical NK cell infusion
    In: Journal of Immunotherapy Jg. 33 (2010) Nr. 2, S. 200 - 210
    ISSN: 1524-9557; 1053-8550; 1537-4513
    Online Volltext: dx.doi.org/
  • Weingarten, C.; Thor, T.; Baumann, M.; Heukamp, L. C.; Buttner, R.; Schramm, Alexander; Eggert, Angelika; Schulte, Johannes; Pajtler, K.
    KDM 1A/LSD1 has a functional role in migration of medulloblastoma cells and their neuronal precursors
    In: Klinische Pädiatrie Jg. 222 (2010) Nr. 3, S. 221
    ISSN: 0300-8630; 1439-3824
  • Pajtler, Kristian; Thor, T.; Baumann, M.; Heukamp, L.; Lim, S.; Kirfel, J.; Schramm, Alexander; Kuhfittig-Kulle, S.; Metzger, E.; Buttner, R.; Schuele, R.; Eggert, Angelika; Schulte, Johannes
    LSD1 is a novel therapeutic target in neuroblastoma (NB) and medulloblastoma (MB)
    In: European Journal of Pediatrics Jg. 169 (2010) Nr. 3, S. 381
    ISSN: 0340-6199; 1432-1076
    Online Volltext: dx.doi.org/
  • Mestdagh, P.; Fredlund, E.; Pattyn, F.; Schulte, Johannes; Muth, D.; Vermeulen, J.; Kumps, C.; Schlierf, S.; De Preter, K.; Van Roy, N.; Noguera, R.; Laureys, G.; Schramm, Alexander; Eggert, Angelika; Westermann, F.; Speleman, F.; Vandesompele, J.
    MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors
    In: Oncogene Jg. 29 (2010) Nr. 9, S. 1394 - 1404
    ISSN: 0950-9232; 1476-5594
    Online Volltext: dx.doi.org/
  • De Brouwer, Sara; De Preter, Katleen; Kumps, Candy; Zabrocki, Piotr; Porcu, Michael; Westerhout, Ellen M.; Lakeman, Arjan; Vandesompele, Jo; Hoebeeck, Jasmien; Van Maerken, Tom; De Paepe, Anne; Laureys, Genevieve; Schulte, Johannes; Schramm, Alexander; Van Den Broecke, Caroline; Vermeulen, Joelle; Van Roy, Nadine; Beiske, Klaus; Renard, Marleen; Noguera, Rosa; Delattre, Olivier; Janoueix-Lerosey, Isabelle; Kogner, Per; Martinsson, Tommy; Nakagawara, Akira; Ohira, Miki; Caron, Huib; Eggert, Angelika; Cools, Jan; Versteeg, Rogier; Speleman, Frank
    Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification
    In: Clinical Cancer Research Jg. 16 (2010) Nr. 17, S. 4353 - 4362
    ISSN: 1078-0432; 1557-3265
    Online Volltext: dx.doi.org/
  • Pajtler, Kristian; Bohrer, Anna; Maurer, Jochen; Schorle, Hubert; Schramm, Alexander; Eggert, Angelika; Schulte, Johannes
    Production of chick embryo extract for the cultivation of murine neural crest stem cells
    In: Journal of Visualized Experiments Jg. 2010 (2010) Nr. 45,
    ISSN: 1940-087X
    Online Volltext: dx.doi.org/ Online Volltext (Open Access)
  • Degen, S.; Kuhfittig-Kulle, Steffi; Schulte, Johannes; Westermann, F.; Schramm, Alexander; Eggert, Angelika; Astrahantseff, K.
    The DNA-binding protein YB-1 is a direct MYCN target and influences repair and resistance in neuroblastoma cell lines
    In: Klinische Pädiatrie Jg. 222 (2010) Nr. 3, S. 219
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Mestdagh, Pieter; Boström, Anna-Karin; Impens, Francis; Fredlund, Erik; Van Peer, Gert; De Antonellis, Pasqualino; von Stedingk, Kristoffer; Ghesquière, Bart; Schulte, Stefanie; Dews, Michael; Thomas-Tikhonenko, Andrei; Schulte, Johannes; Zollo, Massimo; Schramm, Alexander; Gevaert, Kris; Axelson, Håkan; Speleman, Frank; Vandesompele, Jo
    The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma
    In: Molecular Cell Jg. 40 (2010) Nr. 5, S. 762 - 773
    ISSN: 1097-2765; 1097-4164
    Online Volltext: dx.doi.org/
  • Brockmeyer, B.; Schulte, Johannes; Oberthuer, A.; Mestdagh, P.; Pajtler, Kristian; Theissen, J.; Bachmann, Hagen Sjard; Hero, B.; Vandesompele, J.; Berthold, F.; Eggert, Angelika; Schramm, Alexander; Fischer, M.
    ALK Mutation Analysis in Patients of the German Neuroblastoma Study
    In: Klinische Pädiatrie Jg. 221 (2009) Nr. 3, S. 195
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Kirchhoff, G.; Mahlow, E.; Eggert, Angelika; Schramm, Alexander
    Characterisation of stable cell clones derived from an unusual neuroblastoma stage 4S with MYCN amplification
    In: Klinische Pädiatrie Jg. 221 (2009) Nr. 3, S. 200
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Cimmino, F.; Schulte, Johannes; Zollo, M.; Koster, J.; Versteeg, R.; Iolascon, A.; Eggert, Angelika; Schramm, Alexander
    Galectin-1 is a major effector of TrkB-mediated neuroblastoma aggressiveness
    In: Oncogene Jg. 28 (2009) Nr. 19, S. 2015 - 2023
    ISSN: 0950-9232; 1476-5594
    Online Volltext: dx.doi.org/
  • Pajtler, Kristian; Thor, T.; Oles, L.; Baumann, M.; Heukamp, L. C.; Buttner, R.; Kirjel, J.; Schramm, Alexander; Eggert, Angelika; Schulte, Johannes
    LSD 1 is a Potential Therapeutic Target in Medulloblastoma
    In: Klinische Pädiatrie Jg. 221 (2009) Nr. 3, S. 203 - 204
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Schulte, Johannes H.; Schramm, Alexander; Thor, T.; Lim, S.; Pajtler, Kristian; Kuhfittig-Kulle, Steffi; Metzger, E.; Schuele, R.; Buettner, R.; Kirfel, J.; Eggert, Angelika
    Lysine-Specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma : Implications for therapy
    In: Klinische Pädiatrie / XXII. Jahrestagung der Kind-Philipp-Stiftung für Leukämieforschung ; Wilsede, Lüneburger Heide, 10.–13. Juni 2009 Jg. 221 (2009) Nr. 3, S. A61
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Schulte, Johannes H.; Lim, Soyoung; Schramm, Alexander; Friedrichs, Nicolaus; Koster, Jan; Versteeg, Rogier; Ora, Ingrid; Pajtler, Kristian; Klein-Hitpaß, Ludger; Kuhfittig-Kulle, Steffi; Metzger, Eric; Schüle, Roland; Eggert, Angelika; Buettner, Reinhard; Kirfel, Jutta
    Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma : implications for therapy
    In: Cancer Research Jg. 69 (2009) Nr. 5, S. 2065 - 2071
    ISSN: 0008-5472; 1538-7445; 0099-7013; 0099-7374
    Online Volltext: dx.doi.org/ (Open Access)
  • De Preter, Katleen; De Brouwer, Sara; Van Maerken, Tom; Pattyn, Filip; Schramm, Alexander; Eggert, Angelika; Vandesompele, Jo; Speleman, Frank
    Meta-mining of neuroblastoma and neuroblast gene expression profiles reveals candidate therapeutic compounds
    In: Clinical Cancer Research Jg. 15 (2009) Nr. 11, S. 3690 - 3696
    ISSN: 1078-0432; 1557-3265
    Online Volltext: dx.doi.org/
  • Thor, T.; Heukamp, L.; Hahn, H.; Kappler, R.; Buettner, R.; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes
    MicroRNAs 221 and 222 in the Pathogenesis of Solid Childhood Tumors
    In: Klinische Pädiatrie Jg. 221 (2009) Nr. 3, S. 210
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Horn, Sebastian; Schlierf, Stefanie; Schramm, Alexander; Heukamp, Lukas C.; Christiansen, Holger; Buettner, Reinhard; Berwanger, Bernd; Eggert, Angelika
    MicroRNAs in the pathogenesis of neuroblastoma
    In: Cancer Letters Jg. 274 (2009) Nr. 1, S. 10 - 15
    ISSN: 0304-3835; 1872-7980
    Online Volltext: dx.doi.org/
  • Bohrer, A. M.; Mahlow, E.; Maurer, J.; Schorle, H.; Schramm, Alexander; Eggert, Angelika; Schulte, Johannes
    N-myc induces transformation of neural crest stem cells in vitro and in vivo
    In: Klinische Pädiatrie Jg. 221 (2009) Nr. 3, S. 195
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Kuenkele, A.; Baumann, M.; Odersky, Andrea; Deubzer, H.; Witt, O.; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes
    Pharmacologic activation of the p53 pathway using Nutlin-3 inhibits medulloblastoma cell proliferation in vitro
    In: Klinische Pädiatrie Jg. 221 (2009) Nr. 3, S. 201
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Schlierf, S.; Mestdagh, P.; Thor, T.; DePreter, K.; Baumann, M.; Eggert, Angelika; Vandesompele, J.; Schramm, Alexander; Schulte, Johannes
    Prognostic role and functional analyses of miRNA expression in neuroblastoma
    In: Klinische Pädiatrie Jg. 221 (2009) Nr. 3, S. 206
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Terjung, S.; Schulte, Johannes; Schlierf, S.; Schramm, Alexander; Eggert, Angelika; Meyer, H. E.; Stuhler, K.
    Proteomics of neuroblastoma master regulators
    In: Klinische Pädiatrie Jg. 221 (2009) Nr. 3, S. 209
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Schramm, Alexander; Mierswa, Ingo; Kaderali, Lars; Morik, Katharina; Eggert, Angelika; Schulte, Johannes
    Reanalysis of neuroblastoma expression profiling data using improved methodology and extended follow-up increases validity of outcome prediction
    In: Cancer Letters Jg. 282 (2009) Nr. 1, S. 55 - 62
    ISSN: 0304-3835; 1872-7980
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Pentek, Falk; Hartmann, Wolfgang; Schramm, Alexander; Friedrichs, Nicolaus; Øra, Ingrid; Koster, Jan; Versteeg, Rogier; Kirfel, Jutta; Buettner, Reinhard; Eggert, Angelika
    The low-affinity neurotrophin receptor, p75, is upregulated in ganglioneuroblastoma/ganglioneuroma and reduces tumorigenicity of neuroblastoma cells in vivo
    In: International Journal of Cancer Jg. 124 (2009) Nr. 10, S. 2488 - 2494
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Biewald, E.; Mestdagh, P.; Stephan, H.; de Preter, K.; Thor, T.; Baumann, M.; Lohmann, Dietmar; Eggert, Angelika; Spelemann, F.; Schramm, Alexander; Vandesompele, J.; Schulte, Johannes
    The miR-17-92 gene cluster is amplified and overexpressed in retinoblastoma
    In: Klinische Pädiatrie Jg. 221 (2009) Nr. 3, S. 195
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Huebener, Nicole; Fest, Stefan; Hilt, Kerstin; Schramm, Alexander; Eggert, Angelika; Durmus, Tahir; Woehler, Anja; Stermann, Alexander; Bleeke, Matthias; Baykan, Bianca; Weixler, Silke; Gaedicke, Gerhard; Lode, Holger N.
    Xenogeneic immunization with human tyrosine hydroxylase DNA vaccines suppresses growth of established neuroblastoma
    In: Molecular Cancer Therapeutics Jg. 8 (2009) Nr. 8, S. 2392 - 2401
    ISSN: 1535-7163; 1538-8514
    Online Volltext: dx.doi.org/
  • Michels, Evi; Hoebeeck, Jasmien; De Preter, Katleen; Schramm, Alexander; Brichard, Benedicte; De Paepe, Anne; Eggert, Angelika; Laureys, Genevieve; Vandesompele, Jo; Speleman, Frank
    CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23
    In: BMC Cancer Jg. 8 (2008) S. 173
    ISSN: 1471-2407
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Kuhfittig-Kulle, Steffi; Klein-Hitpaß, Ludger; Schramm, Alexander; Biard, Denis S. F.; Pfeiffer, Petra; Eggert, Angelika
    Expression of the TrkA or TrkB receptor tyrosine kinase alters the double-strand break (DSB) repair capacity of SY5Y neuroblastoma cells
    In: DNA Repair Jg. 7 (2008) Nr. 10, S. 1757 - 1764
    ISSN: 1568-7864; 1568-7856
    Online Volltext: dx.doi.org/
  • Pentek, F.; Schramm, Alexander; Astrahantseff, K.; Hartmann, W.; Buttmer, R.; Eggert, Angelika; Schulte, Johannes
    Expression of the p75 neurotrophin receptor reduces tumorigenity of neuroblastoma cells in vivo and in vitro
    In: Klinische Pädiatrie Jg. 220 (2008) Nr. 3, S. 206
    ISSN: 0300-8630; 1439-3824
  • Vandesompele, Jo; Michels, Evi; De Preter, Katleen; Menten, Bjoern; Schramm, Alexander; Eggert, Angelika; Ambros, Peter F.; Combaret, Valerie; Francotte, Nadine; Antonacci, Francesca; De Paepe, Anne; Laureys, Genevive; Speleman, Frank; Van Roy, Nadine
    Identification of 2 putative critical segments of 17q gain in neuroblastoma through integrative genomics
    In: International Journal of Cancer Jg. 122 (2008) Nr. 5, S. 1177 - 1182
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Degen, S.; Zapatka, M.; Schramm, Alexander; Eggert, Angelika; Astrahantseff, K.
    Identification of potential new therapeutic and diagnostic targets for neuroblastoma using patient-derived autoantibodies
    In: Klinische Pädiatrie Jg. 220 (2008) Nr. 3, S. 200
    ISSN: 0300-8630; 1439-3824
  • Becker, J.; Volland, S.; Noskova, I.; Schramm, Alexander; Schweigerer, L. L.; Wilting, J.
    Keratoepithelin reverts the suppression of tissue factor pathway inhibitor 2 by MYCN in human neuroblastoma : a mechanism to inhibit invasion
    In: International Journal of Oncology Jg. 32 (2008) Nr. 1, S. 235 - 240
    ISSN: 1019-6439; 1791-2423
    Online Volltext: dx.doi.org/ (Open Access)
  • Schulte, Johannes; Horn, Sebastian; Otto, Tobias; Samans, Birgit; Heukamp, Lukas C; Eilers, Ursula-Christa; Krause, Michael; Astrahantseff, Kathy; Klein-Hitpaß, Ludger; Buettner, Reinhard; Schramm, Alexander; Christiansen, Holger; Eilers, Martin; Eggert, Angelika; Berwanger, Bernd
    MYCN regulates oncogenic MicroRNAs in neuroblastoma
    In: International Journal of Cancer Jg. 122 (2008) Nr. 3, S. 699 - 704
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Boller, Danielle; Schramm, Alexander; Doepfner, Kathrin T.; Shalaby, Tarek; von Bueren, Andre O.; Eggert, Angelika; Grotzer, Michael A.; Arcaro, Alexandre
    Targeting the phosphoinositide 3-kinase isoform p110delta impairs growth and survival in neuroblastoma cells
    In: Clinical Cancer Research Jg. 14 (2008) Nr. 4, S. 1172 - 1181
    ISSN: 1078-0432; 1557-3265
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Lim, S.; Schramm, Alexander; Ora, I.; Kuhfittig-Kulle, Steffi; Metzger, E.; Schule, R.; Buttner, R.; Eggert, Angelika; Kirfel, J.
    The LSD 1 histone demethylase is highly expressed in poorly differentiated neuroblastoma and is a novel therpeutic target
    In: Klinische Pädiatrie Jg. 220 (2008) Nr. 3, S. 208
    ISSN: 0300-8630; 1439-3824
  • Bitter, A.; Leise, M.; Schramm, Alexander; Eggert, Angelika; Astrahantseff, K.
    The role of heat-shock protein 90 in neuroblastoma tumor biology
    In: Klinische Pädiatrie Jg. 220 (2008) Nr. 3, S. 199
    ISSN: 0300-8630; 1439-3824
  • Schulte, Johannes; Kirfel, Jutta; Lim, Soyoung; Schramm, Alexander; Friedrichs, Nicolaus; Deubzer, Hedwig E.; Witt, Olaf; Eggert, Angelika; Büttner, Reinhard
    Transcription factor AP2alpha (TFAP2a) regulates differentiation and proliferation of neuroblastoma cells
    In: Cancer Letters Jg. 271 (2008) Nr. 1, S. 56 - 63
    ISSN: 0304-3835; 1872-7980
    Online Volltext: dx.doi.org/
  • De Brouwer, Sara; Michels, Evi; Vandesompele, Joe; De Preter, Katleen; Hoebeeck, Jasmien; Vermeulen, Joelle; Schramm, Alexander; Molenaar, Jan J.; Menten, Björn; Marques, Barbara; Stallings, Raymond L; Combaret, Valerie; Devalck, Christine; De Paepe, Anne; Versteeg, Rogier; Eggert, Angelika; Laureys, Geneveive; Van Roy, Nadine; Speleman, Frank
    ArrayCGH based classification of neuroblastoma into genomic subgroups
    In: Chromosome research Jg. 15 (2007) Nr. Suppl. 2, S. 82 - 83
    ISSN: 0967-3849; 1573-6849
    Online Volltext: dx.doi.org/
  • Michels, Evi; Vandesompele, Jo; De Preter, Katleen; Hoebeeck, Jasmien; Vermeulen, Joelle; Schramm, Alexander; Molenaar, Jan J.; Menten, Bjorn; Marques, Barbara; Stallings, Raymond L.; Combaret, Valerie; Devalck, Christine; De Paepe, Anne; Versteeg, Rogier; Eggert, Angelika; Laureys, Genevieve; Van Roy, Nadine; Speleman, Frank
    ArrayCGH-based classification of neuroblastoma into genomic subgroups
    In: Genes, chromosomes & cancer Jg. 46 (2007) Nr. 12, S. 1098 - 1108
    ISSN: 1045-2257; 1098-2264
    Online Volltext: dx.doi.org/
  • De Preter, K.; Vandesompele, J.; Heimann, P.; Yigit, N.; Beckman, S.; Schramm, Alexander; Eggert, Angelika; Stallings, R. L.; Benoit, Y.; Renard, M.; De Paepe, A.; Laureys, G.; Påhlman, S.; Speleman, F.
    Correction : Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes
    In: Genome biology Jg. 8 (2007) Nr. 1, S. 401
    ISSN: 1465-6906; 1465-6914
    Online Volltext: dx.doi.org/
  • Zeng, Yan; Huebener, Nicole; Fest, Stefan; Weixler, Silke; Schroeder, Ulrike; Gaedicke, Gerhard; Xiang, Rong; Schramm, Alexander; Eggert, Angelika; Reisfeld, Ralph A.; Lode, Holger N.
    Fractalkine (CX3CL1)- and interleukin-2-enriched neuroblastoma microenvironment induces eradication of metastases mediated by T cells and natural killer cells
    In: Cancer Res Jg. 67 (2007) Nr. 5, S. 2331 - 2338
    ISSN: 0008-5472; 1538-7445
    Online Volltext: dx.doi.org/
  • Hoebeeck, Jasmien; Michels, Evi; Menten, Bjoern; Van Roy, Nadine; Eggert, Angelika; Schramm, Alexander; De Preter, Katleen; Yigit, Nurten; De Smet, Els; De Paepe, Anne; Laureys, Genevieve; Vandesompele, Jo; Speleman, Frank
    High resolution tiling-path BAC array deletion mapping suggests commonly involved 3p21-p22 tumor suppressor genes in neuroblastoma and more frequent tumors
    In: International Journal of Cancer Jg. 120 (2007) Nr. 3, S. 533 - 538
    ISSN: 0020-7136; 1097-0215
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Horn, Sebastian; Samans, Birgit; Heukamp, Lukas; Eilers, Ursula-Christa; Otto, Tobias; Krause, Michael; Astrahantseff, Kathy; Buttner, Reinhard; Schramm, Alexander; Christiansen, Holger; Eilers, Martin; Berwanger, Bernd; Eggert, Angelika
    N-MYC regulates oncogenic micrornas in neuroblastoma
    In: Pediatric Blood and Cancer Jg. 49 (2007) Nr. 4, S. 429 - 429
    ISSN: 1545-5009; 1545-5017
    Online Volltext: dx.doi.org/
  • Schulte, J. H.; Horn, S.; Schlierf, S.; Samans, B.; Heukamp, L.; Eilers, U.; Otto, T.; Krause, M.; Astrahantseff, K.; Buettner, R.; Schramm, Alexander; Christiansen, H.; Eilers, M.; Eggert, Angelika; Berwanger, B.
    N-Myc regulates oncogenic microRNAs in neuroblastoma
    In: Klinische Pädiatrie Jg. 219 (2007) Nr. 3, S. 192
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Horn, S.; Samans, B.; Heukamp, L.; Eilers, U.; Otto, T.; Krause, M.; Astrahantseff, K.; Buettner, R.; Schramm, Alexander; Christiansen, H.; Eilers, M.; Eggert, Angelika; Berwanger, B.
    N-Myc regulates oncogenic micrortnas in neuroblastoma
    In: European journal of pediatrics Jg. 166 (2007) Nr. 3, S. 278
    ISSN: 0340-6199; 1432-1076
    Online Volltext: dx.doi.org/
  • Kuhfittig-Kulle, Steffi; Schulte, J. H.; Mahlow, E.; Klein-Hitpaß, Ludger; Schramm, Alexander; Pfeiffer, P.; Eggert, Angelika
    Neurotrophin receptor status influences the capacity of nonhomologous DNA end joining INSY5Y neuroblastoma cells
    In: Klinische Pädiatrie Jg. 219 (2007) Nr. 3, S. 187 - 187
    ISSN: 0300-8630; 1439-3824
  • Schramm, Alexander; Vandesompele, Jo; Schulte, Johannes; Dreesmann, Sabine; Kaderali, Lars; Brors, Benedikt; Eils, Roland; Speleman, Frank; Eggert, Angelika
    Translating expression profiling into a clinically feasible test to predict neuroblastoma outcome
    In: Clinical Cancer Research Jg. 13 (2007) Nr. 5, S. 1459 - 1465
    ISSN: 1078-0432; 1557-3265
    Online Volltext: dx.doi.org/
  • Stauder, M. A.; Schmitz, Klaus Jürgen; Leuschner, I.; Schmid, Kurt Werner; Eggert, Angelika; Schramm, Alexander
    Development of a neuroblastoma-specific tissue-microarray as a tool for time- and cost-effective immunohistochemistry analyses
    In: Klinische Pädiatrie Jg. 218 (2006) Nr. 3, S. 195
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Pajtler, Kristian; Schulte, Johannes; Dreesmann, S.; Mahlow, E.; Stauder, M.; Lindemann, Monika; Rebmann, Vera; Grosse-Wilde, H.; Schramm, Alexander; Eggert, Angelika
    Expression of TrkA is a potential regulator of immunogenicity in neuroblastoma cells
    In: Klinische Pädiatrie Jg. 218 (2006) Nr. 3, S. 192 - 192
    ISSN: 0300-8630; 1439-3824
  • De Preter, Katleen; Vandesompele, Jo; Heimann, Pierre; Yigit, Nurten; Beckman, Siv; Schramm, Alexander; Eggert, Angelika; Stallings, Raymond L.; Benoit, Yves; Renard, Marleen; De Paepe, Anne; Laureys, Genevieve; Påhlman, Sven; Speleman, Frank
    Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes
    In: Genome biology Jg. 7 (2006) Nr. 9, S. R84
    ISSN: 1465-6906; 1465-6914; 1474-760X
    Online Volltext: dx.doi.org/
  • Steinbach, D.; Schramm, Alexander; Eggert, Angelika; Onda, M.; Dawczynski, K.; Rump, A.; Pastan, I.; Wittig, S.; Pfaffendorf, N.; Voigt, A.; Zintl, F.; Gruhn, B.
    Identification of a set of seven genes for the monitoring of minimal residual disease in pediatric acute myeloid leukemia
    In: Clinical Cancer Research Jg. 12 (2006) Nr. 8, S. 2434 - 2441
    ISSN: 1078-0432; 1557-3265
    Online Volltext: dx.doi.org/
  • Schwanke, U.; Nabereit, A.; Koehl, U.; Brinkmann, A.; Eggert, Angelika; Schramm, Alexander; Moog, R.
    Isolation of CD3-/CD56+natural killer cells from whole blood derived buffy coats
    In: Bone marrow transplantation Jg. 37 (2006) Nr. Suppl. 1, S. S303
    ISSN: 0268-3369; 1476-5365
    Online Volltext: dx.doi.org/
  • Becker, Jürgen; Erdlenbruch, B.; Noskova, I.; Schramm, Alexander; Aumailley, M.; Schorderet, D. F.; Schweigerer, L.
    Keratoepithelin suppresses the progression of experimental human neuroblastomas
    In: Cancer research Jg. 66 (2006) Nr. 10, S. 5314 - 5321
    ISSN: 0008-5472; 1538-7445; 0099-7013; 0099-7374
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Schramm, Alexander; Samans, B.; Krause, M.; Horn, S.; Fagin, A.; Astrahantseff, K.; Klein-Hitpaß, Ludger; Witt, O.; Westermann, F.; Christiansen, H.; Eilers, M.; Berwanger, B.; Eggert, Angelika
    MicroRNA expression analysis in neuroblastoma using pligonuclectide arrays
    In: Klinische Pädiatrie Jg. 218 (2006) Nr. 3, S. 194
    ISSN: 0300-8630; 1439-3824
  • Pressel, T.; Schramm, Alexander; Schulte, Johannes; Klein-Hitpaß, Ludger; Eggert, Angelika
    Microarray analysis defines IPL/TSSC3 as a potential target mediating the synergistic effects of combined thermo-chemotherapy in neuroblastoma cells
    In: Klinische Pädiatrie Jg. 218 (2006) Nr. 3, S. 192 - 193
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Scaruffi, P.; Valent, A.; Schramm, Alexander; Astrahantseff, K.; Eggert, Angelika; Tonini, G. P.
    Application of microarray-based technology to neuroblastoma
    In: Cancer letters Jg. 228 (2005) Nr. 1-2, S. 13 - 20
    ISSN: 0304-3835; 1872-7980
    Online Volltext: dx.doi.org/
  • Schramm, Alexander; Schulte, Johannes; Astrahantseff, K.; Apostolov, O.; Limpt, V.; Sieverts, H.; Kuhfittig-Kulle, Steffi; Pfeiffer, Petra; Versteeg, R.; Eggert, Angelika
    Biological effects of TrkA and TrkB receptor signaling in neuroblastoma
    In: Cancer letters Jg. 228 (2005) Nr. 1-2, S. 143 - 153
    ISSN: 0304-3835; 1872-7980
    Online Volltext: dx.doi.org/
  • Grasemann, Corinna; Gratias, S.; Stephan, H.; Schüler, A.; Schramm, Alexander; Klein-Hitpaß, Ludger; Rieder, H.; Schneider, S.; Kappes, F.; Eggert, Angelika; Lohmann, Dietmar
    Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma
    In: Oncogene Jg. 24 (2005) Nr. 42, S. 6441 - 6449
    ISSN: 0950-9232; 1476-5594
    Online Volltext: dx.doi.org/
  • Schramm, Alexander; von Schuetz, V.; Christiansen, H.; Havers, Werner; Papoutsi, M.; Wilting, J.; Schweigerer, L.
    High activin A-expression in human neuroblastoma : suppression of malignant potential and correlation with favourable clinical outcome
    In: Oncogene Jg. 24 (2005) Nr. 4, S. 680 - 687
    ISSN: 0950-9232; 1476-5594
    Online Volltext: dx.doi.org/
  • Steinbach, D.; Schramm, Alexander; Eggert, Angelika; Wittig, S.; Pfaffendorf, N.; Voigt, A.; Zintl, F.; Gruhn, B.
    Identification of a set of seven genes for the monitoring of minimal residual disease in pediatric acute myeloid leukemia
    In: Blood Jg. 106 (2005) Nr. 11, S. 422A
    ISSN: 0006-4971; 1528-0020
  • Sitek, B.; Apostolov, O.; Stühler, K.; Pfeiffer, K.; Meyer, H. E.; Eggert, Angelika; Schramm, Alexander
    Identification of dynamic proteome changes upon ligand activation of Trk-receptors using two-dimensional fluorescence difference gel electrophoresis and mass spectrometry
    In: Molecular and Cellular Proteomics Jg. 4 (2005) Nr. 3, S. 291 - 299
    ISSN: 1535-9476; 1535-9484
    Online Volltext: dx.doi.org/
  • Sitek, B.; Apostolov, O.; Stuhler, K.; Pfeiffer, K.; Meyer, H. E.; Eggert, Angelika; Schramm, Alexander
    Identification of dynamic proteome changes upon ligand activation of trk-receptors using two-dimensional fluorescence difference gel electrophoresis and mass spectrometry
    In: Molecular and Cellular Proteomics Jg. 4 (2005) Nr. 8, S. 1210
    ISSN: 1535-9476; 1535-9484
  • Schulte, Johannes; Schramm, Alexander; Klein-Hitpaß, Ludger; Klenk, M.; Wessels, H.; Hauffa, Berthold; Eils, J.; Eils, R.; Brodeur, G. M.; Schweigerer, L.; Havers, Werner; Eggert, Angelika
    Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas
    In: Oncogene Jg. 24 (2005) Nr. 1, S. 165 - 177
    ISSN: 0950-9232; 1476-5594
  • van Limpt, V.; Chan, A.; Schramm, Alexander; Eggert, Angelika; Versteeg, R.
    Phox2B mutations and the Delta-Notch pathway in neuroblastoma
    In: Cancer letters Jg. 228 (2005) Nr. 1-2, S. 59 - 63
    ISSN: 0304-3835; 1872-7980
    Online Volltext: dx.doi.org/
  • Schramm, Alexander; Schulte, Johannes; Klein-Hitpaß, Ludger; Havers, Werner; Sieverts, H.; Berwanger, B.; Christiansen, H.; Warnat, P.; Brors, B.; Eils, J.; Eils, R.; Eggert, Angelika
    Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling
    In: Oncogene Jg. 24 (2005) Nr. 53, S. 7902 - 7912
    ISSN: 0950-9232; 1476-5594
    Online Volltext: dx.doi.org/
  • Steinbach, D.; Schramm, Alexander; Eggert, Angelika; Wittig, S.; Pfaffendorf, N.; Voigt, A.; Zintl, F.; Gruhn, B.
    Quantitative phenotyping and discriminant analysis improve scoring classification in late B-lymphoproliferative disorders
    In: Blood Jg. 106 (2005) Nr. 11, S. 422A
    ISSN: 0006-4971; 1528-0020
  • Steinbach, D.; Schramm, Alexander; Eggert, Angelika; Wittig, S.; Zintl, F.; Gruhn, B.
    Identification of new markers for the detection of minimal residual disease in AML by gene expression profiling and real time PCR
    In: Blood Jg. 104 (2004) Nr. 11, S. 554A
    ISSN: 0006-4971; 1528-0020
  • Lang, D.; Patti, R.; Schulte, Johannes; Schramm, Alexander; Shalaby, T.; Phillips, P. C.; Eggert, Angelika; Grotzer, M. A.
    NT-3 mediated signaling pathways in DAOY medulloblastoma cells
    In: Neuro-Oncology Jg. 6 (2004) Nr. 4, S. 409 - 409
    ISSN: 1522-8517; 1523-5866
    Online Volltext: dx.doi.org/
  • Walden, H.; Taylor, G. L.; Lorentzen, E.; Pohl, E.; Lilie, H.; Schramm, Alexander; Knura, T.; Stubbe, K.; Tjaden, B.; Hensel, R.
    Structure and function of a regulated archaeal triosephosphate isomerase adapted to high temperature
    In: Journal of Molecular Biology (JMB) Jg. 342 (2004) Nr. 3, S. 861 - 875
    ISSN: 1089-8638; 0022-2836
    Online Volltext: dx.doi.org/
  • van Limpt, V.; Schramm, Alexander; van Lakeman, A.; Sluis, P.; Chan, A.; van Noesel, M.; Baas, F.; Caron, H.; Eggert, Angelika; Versteeg, R.
    The Phox2B homeobox gene is mutated in sporadic neuroblastomas
    In: Oncogene Jg. 23 (2004) Nr. 57, S. 9280 - 9288
    ISSN: 0950-9232; 1476-5594
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Schramm, Alexander; Pressel, T.; Klein-Hitpaß, Ludger; Kremens, Bernhard; Eils, J.; Havers, Werner; Eggert, Angelika
    Microarray-analysis : a new approach to study the molecular mechanisms of thermo-chemotherapy
    In: Klinische Pädiatrie Jg. 215 (2003) Nr. 6, S. 298 - 302
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Schramm, Alexander; Apostolov, O.; Sitek, B.; Pfeiffer, K.; Stühler, K.; Meyer, H. E.; Havers, Werner; Eggert, Angelika
    Proteomics : techniques and applications in cancer research
    In: Klinische Pädiatrie Jg. 215 (2003) Nr. 6, S. 293 - 297
    ISSN: 0300-8630; 1439-3824
    Online Volltext: dx.doi.org/
  • Wai, D. H.; Schaefer, K. L.; Schramm, Alexander; Korsching, E.; Van Valen, F.; Ozaki, T.; Boecker, W.; Schweigerer, L.; Dockhorn-Dworniczak, B.; Poremba, C.
    Expression analysis of pediatric solid tumor cell lines using oligonucleotide microarrays
    In: International journal of oncology Jg. 20 (2002) Nr. 3, S. 441 - 451
    ISSN: 1019-6439; 1791-2423
  • Schramm, Alexander; Siebers, Bettina; Tjaden, Britta; Brinkmann, Henner; Hensel, Reinhard
    Pyruvate kinase of the hyperthermophilic crenarchaeote Thermoproteus tenax : Physiological role and phylogenetic aspects
    In: Journal of Bacteriology Jg. 182 (2000) Nr. 7, S. 2001 - 2009
    ISSN: 0021-9193; 1098-5530
    Online Volltext: dx.doi.org/ (Open Access)

    • Vorworte / Nachworte

  • Althoff, Kristina; Schramm, Alexander
    Editorial: MYCN-mediated murine cancer models
    In: Aging Jg. 9 (2017) Nr. 4, S. 1084 - 1085
    ISSN: 1945-4589
    Online Volltext: dx.doi.org/

    • Abstracts

  • Stockhammer, P.; Ho, C.S.L.; Bankfalvi, Agnes; Plönes, T.; Hegedus, L.; Schuler, Martin; Aigner, Clemens; Schramm, Alexander; Hegedus, B.
    A Novel Patient Derived Synchronous Cell Pair with Different Mutations in an ALK-Rearranged Lung Adenocarcinoma Underlines Tumor Heterogeneity
    In: Journal of Thoracic Oncology Jg. 14 (2019) Nr. 10, Supplement, S. S571 - S572
    ISSN: 1556-1380; 1556-0864
    Online Volltext: dx.doi.org/
  • Nothdurft, S.; Breitenbücher, Frank; Okimoto, R.; Bivona, T.; Grüner, Barbara M.; Hoelzel, M.; Forster, J.; Kalmbach, S.; Schramm, Alexander; Schuler, Martin
    MA17.07 Identification of AHR as a Novel Regulator of Lung Cancer Metastasis
    In: Journal of Thoracic Oncology Jg. 14 (2019) Nr. 10, Supplement, S. S319
    ISSN: 1556-1380; 1556-0864
    Online Volltext: dx.doi.org/
  • Menke, Katrin; Schwermer, Melanie; Falke, Katharina; Eisenbraun, Jürgen; Schramm, Alexander; Zuzak, Zuzak, Tycho Jan;
    Preclinical investigation of interaction of mistletoe extract (Viscum album L.) with radio- and chemotherapy in pediatric tumor cell lines
    7th Mistletoe Symposium: Mistletoe in Tumour Therapy Basic Research and Clinical Practice, 7 - 9 November 2019, Nonnweiler-Otzenhausen, Germany,
    In: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology Jg. 61 (2019) Nr. Supplement 1, S. 4
    ISSN: 0944-7113; 1618-095X
    Online Volltext: dx.doi.org/
  • Rebmann, Vera; Manvailer, Luis Felipe Santos; Wagner, Bettina; Rieb, Anja; Collenburg, Monika; Horn, Peter; Pajtler, Kristian; Schramm, Alexander;
    Soluble NKG2DL are released by Tumor Cell Lines in a Mutually exclusive fashion as free Molecules or via extracellular vesicles
    28th EFI European Immunogenetics and Histocompatibility Conference Stockholm, Sweden, June 25th–28th, 2014,
    In: Tissue Antigens Jg. 84 (2014) Nr. 1, S. 17 - 18
    ISSN: 0001-2815; 1399-0039
    Online Volltext: dx.doi.org/
  • Hilhorst, Riet; Hovestad, Liesbeth; de Wijn, Rik; Pijnenburg, Dirk; Ruijtenbeek, Rob; Schramm, Alexander; Eggert, Angelika; Schulte, Johannes H.
    ALK F1174L kinase activity as driver of cell proliferation in neuroblastoma cell line models and neuroblastoma tumors
    In: Cancer Research / AACR 103rd Annual Meeting 2012 ; Mar 31‐Apr 4, 2012, Chicago Jg. 72 (2012) Nr. 8, Suppl., S. 1683
    ISSN: 0008-5472; 1538-7445
    Online Volltext: dx.doi.org/
  • Pajtler, Kristian; Weingarten, Christina; Thor, Theresa; Kuenkele, Annette; Fleischhack, Gudrun; Heukamp, Lukas C; Buettner, Reinhard; Kirfel, Jutta; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes;
    Lysin-Specific Histone Dementhylase 1(LSD1) is a promising new Epigenetic Theapy target Crucially involved in the migration of Medulloblastoma Cells
    15th International Symposium on Pediatric Neuro-Oncology, June 24-27 2012 Toronto, Ontario, Canada,
    In: Neuro-Oncology Jg. 14 (2012) Nr. Suppl. 1, S. i92
    ISSN: 1522-8517; 1523-5866
    Online Volltext: dx.doi.org/
  • Thor, Theresa; Mestdagh, Pieter; Vandesomple, J. o.; Fuchs, Helmut; Durner, Valerie G; de Angelis, Martin Hr; Heukamp, Lukas; Kuenkele, Annette; Pajtler, Kristian; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes;
    miR-34a is dispensable for normal development but its loss Accelerates medulloblastoma formation
    15th International Symposium on Pediatric Neuro-Oncology, June 24-27 2012 Toronto, Ontario, Canada,
    In: Neuro-Oncology Jg. 14 (2012) Nr. Suppl. 1, S. 89
    ISSN: 1522-8517; 1523-5866
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Schowe, Benjamin; Mestdagh, Pieter; Kaderali, Lars; Kalaghatgi, Prabhav; Schlierf, Stefanie; Vermeulen, Joelle; Brockmeyer, Bent; Pajtler, Kristian; Thor, Theresa; de Preter, Katleen; Speleman, Frank; Marik, Katharina; Eggert, Angelika; Vandesompele, Jo; Schramm, Alexander;
    Accurate prediction of neuroblastoma outcome based on miRNA expression profiles
    42nd Congress of the International Society of Pediatric Oncology (SIOP), October 21-24, 2010, Boston, USA,
    In: Pediatric Blood and Cancer Jg. 55 (2010) Nr. 5, S. 812
    ISSN: 1545-5009; 1545-5017
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Marshall, Tobias; Martin, Marcel; Rosenstiel, Philipp; Mestdagh, Pieter; Schlierf, Stefanie; Thor, Theresa; Vandesompele, Jo; Eggert, Angelika; Schreiber, Stefan; Rahmann, Sven; Schramm, Alexander;
    Deep Sequencing Revals Differential Expression of Micrornas in Favourable Versus Unfavourable Neuroblastoma
    42nd Congress of the International Society of Pediatric Oncology (SIOP) in Boston,
    In: Pediatric Blood and Cancer Jg. 55 (2010) Nr. 5, S. 826 - 827
    ISSN: 1545-5009; 1545-5017; 0098-1532; 1096-911X
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Bachmann, Hagen Sjard; Brockmeyer, Bent; Nowacki, Sandra; Kahlert, Yvonne; Oberthur, Andre; de Preter, Katleen; Pajtler, Kristian; Theissen, Jessica; Westermann, Frank; Speleman, Frank; Vandesompele, Jo; Berthold, Frank; Eggert, Angelika; Hero, Barbara; Schramm, Alexander; Fischer, Matthias;
    High Expression of the alk Receptor Tyrosine Kinase Precedes Mutation as a Determining Factor of Unfavourable Phenotype in Primary Neuroblastoma
    42nd Congress of the International Society of Pediatric Oncology (SIOP), October 21-24, 2010, Boston, USA,
    In: Pediatric Blood and Cancer Jg. 55 (2010) Nr. 5, S. 827
    ISSN: 1545-5009; 1545-5017; 0098-1532; 1096-911X
    Online Volltext: dx.doi.org/
  • Kuenkele, Annette; de Preter, Katleen; Vandesompele, Jo; Pajtler, Kristian; Heukamp, Lukas; Grotzer, Michael; Schramm, Alexander; Eggert, Angelika; Schulte, Johannes;
    Pharmacologic Activation of the P53 Pathway by Nutlin-3 Inhibits Medulloblastoma Cell Proliferation in Vitro
    42nd Congress of the International Society of Pediatric Oncology (SIOP), October 21-24, 2010, Boston, USA,
    In: Pediatric Blood and Cancer Jg. 55 (2010) Nr. 5, S. 918
    ISSN: 1545-5009; 1545-5017; 1096-911X; 0098-1532
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Schowe, Benjamin; Martin, Marcel; Rahmann, Sven; Theissen, Jessica; Hero, Barbara; Morik, Katharina; Schramm, Alexander; Eggert, Angelika;
    Exon-Level gene expression analysis of primary neuroblastomas improves risk prediction and identifies jaridic as a novel Therapeutic target
    41st Annual conference of International Society of Paediatric Oncology SIOP 2009, Sao Paulo, Brazil, October 5–9, 2009,
    In: Pediatric Blood and Cancer Jg. 53 (2009) Nr. 5, S. 742 - 743
    ISSN: 1545-5009; 1545-5017; 1096-911X; 0098-1532
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Pajtler, Kristian; Buettner, Reinhard; Kirfel, Jutta; Thor, Theresa; Schramm, Alexander; Eggert, Angelika;
    LSD1 is a Potential Therapeutic Target in Medulloblastoma
    41st Annual conference of International Society of Paediatric Oncology SIOP 2009, October 5–9, 2009, Sao Paulo, Brazil,
    In: Pediatric Blood and Cancer Jg. 53 (2009) Nr. 5, S. 826
    ISSN: 1545-5009; 1545-5017; 1096-911X; 0098-1532
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Bohrer, Anna; Mahlow, Ellen; Maurer, Jochen; Schorle, Hubert; DePreter, Katleen; Vandesompele, Jo; Speleman, Frank; Schlierf, Stefanie; Pajtler, Kristian; Schramm, Alexander; Eggert, Angelika;
    Modeling Neuroblastomagenesis from neural crest Stem Cells in Vitro and in Vivo
    41st Annual conference of International Society of Paediatric Oncology SIOP 2009, Sao Paulo, Brazil, October 5–9, 2009,
    In: Pediatric Blood and Cancer Jg. 53 (2009) Nr. 5, S. 703 - 704
    ISSN: 1545-5009; 1545-5017; 0098-1532; 1096-911X
    Online Volltext: dx.doi.org/
  • Schulte, Johannes; Biewald, Eva; Mestdagh, Pieter; Stephan, Harald; Katleen, DePreter; Lohmann, Dietmar; Spelemann, Frank; Schramm, Alexander; Vandesompele, Jo; Eggert, Angelika;
    The MIR-17-92 Gene Cluster is Amplified an overexpressed in Rettinoblastoma
    41st Annual conference of International Society of Paediatric Oncology SIOP 2009, Sao Paulo, Brazil, October 5–9, 2009,
    In: Pediatric Blood and Cancer Jg. 53 (2009) Nr. 5, S. 735
    ISSN: 1545-5009; 1545-5017; 0098-1532; 1096-911X
    Online Volltext: dx.doi.org/

    • Beiträge in Sammelwerken und Tagungsbänden

  • Schramm, Alexander
    Proteomics and Cancer Risk Assessment
    In: Cancer Risk Evaluation: Methods and Trends / Obe, Günter; Jandrig, Burkhard; Marchant, Gary E.; Schütz, Holger; Wiedermann, Peter M. (Hrsg.) 2011, S. 207 - 217
    ISBN: 978-3-527-32753-9; 978-3-527-63461-3
    Online Volltext: dx.doi.org/

    • Bücher/Sammelwerke/Tagungsbände

  • Schramm, Alexander
    Identifizierung und Charakterisierung von Kandidatengenen in embryonalen Tumoren durch die Anwendung molekularer Hochdurchsatzverfahren
    Duisburg, Essen (2008) 1 CD-ROM