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Es wurde 1 Person gefunden.
E-Mail
Funktionen
- Privatdozent/in, Institut für Zellbiologie (Tumorforschung)
Aktuelle Veranstaltungen
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2020 WS
- Laborpraktikum II für Masterstudenten der medizinischen Biologie (WP)
- Neue Literatur (Zellbiologie, experimentelle Krebsforschung) (*)
- Laborpraktikum III für Masterstudenten der medizinischen Biologie (WP)
- Mitarbeiterseminar zur Besprechung aktueller Arbeiten
- Anleitung zu selbständigen wissenschaftlichen Arbeiten (*)
- Seminar für Zellbiologie und experimentelle Krebsforschung (mit Gastsprechern) (*)
Vergangene Veranstaltungen (max. 10)
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2020 SS
- Seminar für Zellbiologie und experimentelle Krebsforschung (mit Gastsprechern) (*)
- Mitarbeiterseminar zur Besprechung aktueller Arbeiten
- Neue Literatur (Zellbiologie, experimentelle Krebsforschung) (*)
- Anleitung zu selbständigen wissenschaftlichen Arbeiten (*)
- Seminar Neue Literatur der Zell- und Molekularbiologie für med. Biologen (Bachelor) Gruppe II
- Praktikum Zell- und Molekularbiologie für med. Biologen (Bachelor) (PV)
- Neue Literatur der Zell- und Molekularbiologie für Med. Biologen
- Seminar Neue Literatur der Zell- und Molekularbiologie für med. Biologen (Bachelor) Gruppe I
- 2019 WS
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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RUNX3 transcript variants have distinct roles in ovarian carcinoma and differently influence platinum sensitivity and angiogenesisIn: Cancers Jg. 13 (2021) Nr. 3, S. 476
ISSN: 2072-6694Online Volltext: dx.doi.org/ (Open Access) -
Detection of doxorubicin, cisplatin and therapeutic antibodies in formalin-fixed paraffin-embedded human cancer cellsIn: Histochemistry and Cell Biology Jg. 153 (2020) Nr. 5, S. 367 - 377
ISSN: 1432-119X; 0948-6143Online Volltext: dx.doi.org/ (Open Access) -
Diphenhydramine increases the therapeutic window for platinum drugs by simultaneously sensitizing tumor cells and protecting normal cellsIn: Molecular Oncology Jg. 14 (2020) Nr. 4, S. 686 - 703
ISSN: 1878-0261; 1574-7891Online Volltext: dx.doi.org/ (Open Access) -
Lineage-specific control of TFIIH by MITF determines transcriptional homeostasis and DNA repairIn: Oncogene Jg. 38 (2019) Nr. 19, S. 3616 - 3635
ISSN: 1476-5594; 0950-9232Online Volltext: dx.doi.org/ (Open Access) -
Metformin enhances the radiosensitizing effect of cisplatin in non-small cell lung cancer cell lines with different cisplatin sensitivitiesIn: Scientific Reports Jg. 9 (2019) S. 1282
ISSN: 2045-2322Online Volltext: dx.doi.org/ (Open Access) -
Combined effects of metformin and cisplatin on radiation sensitivity in non-small cell lung cancer cellsIn: Strahlentherapie und Onkologie Jg. 194 (2018) Nr. Suppl.1, S. 100
ISSN: 0179-7158; 1439-099XOnline Volltext: dx.doi.org/ -
Multifaceted mechanisms of cisplatin resistance in long-term treated urothelial carcinoma cell linesIn: International Journal of Molecular Sciences Jg. 19 (2018) Nr. 2, S. 590
ISSN: 1422-0067Online Volltext: dx.doi.org/ (Open Access) -
Cisplatin alters the function and expression of N-type voltage-gated calcium channels in the absence of morphological damage of sensory neurons.In: Molecular Pain Jg. 13 (2017) S. 1744806917746565
ISSN: 1744-8069Online Volltext: dx.doi.org/ (Open Access) -
Cisplatin-induced neuropathic pain is mediated by upregulation of N-type voltage-gated calcium channels in dorsal root ganglion neuronsIn: Experimental Neurology Jg. 288 (2017) S. 62 - 74
ISSN: 1090-2430; 0014-4886Online Volltext: dx.doi.org/ -
Comprehensive Molecular Characterization of a Cisplatin-Specific Monoclonal AntibodyIn: Molecular Pharmaceutics Jg. 14 (2017) Nr. 12, S. 4454 - 4461
ISSN: 1543-8384Online Volltext: dx.doi.org/ -
Differential effect of quercetin on cisplatin-induced toxicity in kidney and tumor tissuesIn: Food and Chemical Toxicology Jg. 107 (2017) S. 226 - 236
ISSN: 1873-6351; 0278-6915Online Volltext: dx.doi.org/ -
Metformin potentiates radiosensitizing effect of cisplatin in NSCLC cellsIn: Strahlentherapie und Onkologie Jg. 193 (2017) Nr. Suppl.1, S. 27
ISSN: 0179-7158; 1439-099X -
Tribbles 2 mediates cisplatin sensitivity and DNA damage response in epithelial ovarian cancerIn: International Journal of Cancer Jg. 141 (2017) Nr. 8, S. 1600 - 1614
ISSN: 0020-7136; 1097-0215Online Volltext: dx.doi.org/ -
DNA damage tolerance pathway involving DNA polymerase ? and the tumor suppressor p53 regulates DNA replication fork progressionIn: Proceedings of the National Academy of Sciences of the United States of America Jg. 113 (2016) Nr. 30, S. E4311 - 9
ISSN: 1091-6490; 0027-8424Online Volltext: dx.doi.org/ (Open Access) -
Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific MannerIn: Molecular Cancer Research Jg. 14 (2016) Nr. 11, S. 1110 - 1123
ISSN: 1541-7786; 1557-3125Online Volltext: dx.doi.org/ -
Lovastatin prevents cisplatin-induced activation of pro-apoptotic DNA damage response (DDR) of renal tubular epithelial cellsIn: Toxicology and Applied Pharmacology Jg. 292 (2016) S. 103 - 114
ISSN: 1096-0333; 0041-008XOnline Volltext: dx.doi.org/ -
ΔNp63 activates the Fanconi anemia DNA repair pathway and limits the efficacy of cisplatin treatment in squamous cell carcinomaIn: Nucleic Acids Research Jg. 44 (2016) Nr. 7, S. 3204 - 3218
ISSN: 1362-4962; 0301-5610; 0305-1048Online Volltext: dx.doi.org/ (Open Access) -
DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar EfficiencyIn: Photochemistry and Photobiology Jg. 91 (2015) Nr. 5, S. 1173 - 1180
ISSN: 0031-8655Online Volltext: dx.doi.org/ -
HIPEC ROC I : A phase i study of cisplatin administered as hyperthermic intraoperative intraperitoneal chemoperfusion followed by postoperative intravenous platinum-based chemotherapy in patients with platinum-sensitive recurrent epithelial ovarian cancerIn: International Journal of Cancer Jg. 136 (2015) Nr. 3, S. 699 - 708
ISSN: 0020-7136; 1097-0215Online Volltext: dx.doi.org/ (Open Access) -
Platinum-induced kidney damage : Unraveling the DNA damage response (DDR) of renal tubular epithelial and glomerular endothelial cells following platinum injuryIn: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Jg. 1853 (2015) Nr. 3, S. 685 - 698
ISSN: 0167-4889; 1879-2596Online Volltext: dx.doi.org/ (Open Access) -
Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulationIn: OncoTarget Jg. 5 (2014) Nr. 23, S. 11778 - 11791
ISSN: 1949-2553Online Volltext: dx.doi.org/ (Open Access) -
Inhibition of PARP activity by PJ34 sensitises NSCLC cells to cisplatinIn: Lung Cancer Jg. 83 (2014) Nr. Suppl. 1, S. 2
ISSN: 0169-5002Online Volltext: dx.doi.org/ -
Regulation of the functional interface between nucleotide excision repair and transcription by MITF modulates melanoma growthIn: Cancer Research Jg. 74 (2014) Nr. 19 Suppl., S. 2950
ISSN: 0008-5472Online Volltext: dx.doi.org/ -
Splenic macrophages induce chemotherapy resistance via DNA damage repairIn: Cancer Research Jg. 74 (2014) Nr. Suppl. 19, S. 3771
ISSN: 0008-5472; 1538-7445Online Volltext: dx.doi.org/ -
Spongean alkaloids protect rat kidney cells against cisplatin-induced cytotoxicityIn: Anti-Cancer Drugs Jg. 25 (2014) Nr. 8, S. 917 - 929
ISSN: 1473-5741; 0959-4973Online Volltext: dx.doi.org/ -
2 MicroRNA profiling and cisplatin–DNA interactions in an isogenic model of cisplatin resistant NSCLC cell linesIn: Lung Cancer Jg. 79 (2013) Nr. Suppl. 1, S. 1
ISSN: 0169-5002Online Volltext: dx.doi.org/ -
Comparative analysis of the sensitivity of normal rat kidney cells towards different types of platinum compoundsIn: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 386 (2013) Nr. Suppl. 1, S. 45
ISSN: 0028-1298 -
ERCC1 isoform expression and DNA repair in non-small-cell lung cancerIn: The New England Journal of Medicine Jg. 368 (2013) Nr. 12, S. 1101 - 1110
ISSN: 1533-4406; 0028-4793Online Volltext: dx.doi.org/ -
Effect of sorafenib combined with cytostatic agents on hepatoblastoma cell lines and xenograftsIn: The British Journal of Cancer: BJC Jg. 108 (2013) Nr. 2, S. 334 - 341
ISSN: 1532-1827; 0007-0920Online Volltext: dx.doi.org/ (Open Access) -
FTO levels affect RNA modification and the transcriptomeIn: European Journal of Human Genetics Jg. 21 (2013) Nr. 3, S. 317 - 323
ISSN: 1018-4813; 1476-5438Online Volltext: dx.doi.org/ -
Formation and repair kinetics of Pt-(GpG) DNA adducts in extracted circulating tumour cells and response to platinum treatmentIn: The British Journal of Cancer: BJC Jg. 109 (2013) Nr. 5, S. 1223 - 1229
ISSN: 1532-1827; 0007-0920Online Volltext: dx.doi.org/ (Open Access) -
Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signatureIn: PLoS ONE Jg. 8 (2013) Nr. 1, S. e54193
ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access) -
PARP1 impact on DNA repair of platinum adducts: Preclinical and clinical read-outsIn: Lung Cancer Jg. 80 (2013) Nr. 2, S. 216 - 222
ISSN: 1872-8332; 0169-5002Online Volltext: dx.doi.org/ -
Parb inhibition increases sensitivity of NSCLC cells to cisplatinIn: Journal of Thoracic Oncology Jg. 8 (2013) Nr. Suppl. 2, S. 470
ISSN: 1556-1380; 1556-0864 -
Pre-therapeutic ex-vivo repair kinetics of cisplatin-DNA-adducts in circulating tumor cells (CTC) as platinum resistance testIn: Lung Cancer Jg. 79 (2013) Nr. Suppl. 1, S. 2
ISSN: 0169-5002Online Volltext: dx.doi.org/ -
Cisplatin resistance induced in germ cell tumour cells is due to reduced susceptibility towards cell death but not to altered DNA damage induction or repairIn: Cancer Letters Jg. 324 (2012) Nr. 2, S. 171 - 178
ISSN: 0304-3835; 1872-7980Online Volltext: dx.doi.org/ -
Efficient pharmacological prevention of the major side effects of cisplatin without affecting the antineoplastic effiacy in vivoIn: Annals of Oncology Jg. 23 (2012) Nr. Suppl. 1, S. 25
ISSN: 0923-7534; 1569-8041 -
Microrna profiling and CDDP-GPG dna adduct formation analysis in a panel of cisplatin resistant non-small cell lung cancer cell linesIn: Annals of Oncology Jg. 23 (2012) Nr. Suppl. 9, S. 68
ISSN: 0923-7534; 1569-8041 -
On the complexity and dynamics of in vivo Cisplatin-DNA adduct formation using HPLC/ICP-MSIn: Metallomics Jg. 4 (2012) Nr. 10, S. 1098 - 1104
ISSN: 1756-5901; 1756-591XOnline Volltext: dx.doi.org/ -
Prognostic Impact of Vitamin B6 Metabolism in Lung CancerIn: Cell Reports Jg. 2 (2012) Nr. 2, S. 257 - 269
ISSN: 2211-1247Online Volltext: dx.doi.org/ (Open Access) -
Structures of oxaliplatin-oligonucleotide adducts from DNAIn: Journal of Mass Spectrometry Jg. 47 (2012) Nr. 10, S. 1282 - 1293
ISSN: 1096-9888; 1076-5174; 1375-1494Online Volltext: dx.doi.org/ -
Differential Melanoma-Chemoresistence to Temozolomide within varying Treatment Schemes : DNA-Damage-Accumulation as DeterminantsIn: Journal der Deutschen Dermatologischen Gesellschaft Jg. 9 (2011) Nr. 9, S. 791 - 791
ISSN: 1610-0379; 1610-0387 -
Differential contributory roles of nucleotide excision and homologous recombination repair for enhancing cisplatin sensitivity in human ovarian cancer cellsIn: Molecular Cancer (2011) S. 24
ISSN: 1476-4598Online Volltext: dx.doi.org/ Online Volltext (Open Access) -
Temozolomide chemoresistance heterogeneity in melanoma with different treatment regimens : DNA damage accumulation contributionIn: Melanoma Research Jg. 21 (2011) Nr. 3, S. 206 - 216
ISSN: 1473-5636Online Volltext: dx.doi.org/ -
p53 Hypersensitivity Is the Predominant Mechanism of the Unique Responsiveness of Testicular Germ Cell Tumor (TGCT) Cells to CisplatinIn: PLoS ONE Jg. 6 (2011) Nr. 4,
ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access) -
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancerIn: Genes and Development Jg. 24 (2010) Nr. 8, S. 837 - 852
ISSN: 1549-5477; 0890-9369Online Volltext: dx.doi.org/ -
Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expressionIn: Molecular Cancer Jg. 9 (2010) S. 248
ISSN: 1476-4598Online Volltext: dx.doi.org/ (Open Access) -
Evoked pain behavior and spinal glia activation is dependent on tumor necrosis factor receptor 1 and 2 in a mouse model of bone cancer painIn: Neuroscience Jg. 169 (2010) Nr. 1, S. 463 - 474
ISSN: 0306-4522; 1873-7544Online Volltext: dx.doi.org/ -
Recombinant human erythropoietin counteracts cisplatin-induced visceral hyperalgesiaIn: Neuroscience Bulletin Jg. 26 (2010) Nr. 4, S. 282 - 288
ISSN: 1995-8218; 1673-7067Online Volltext: dx.doi.org/ -
Transcriptional regulation of renal cytoprotective genes by Nrf2 and its potential use as a therapeutic target to mitigate cisplatin-induced nephrotoxicityIn: The Journal of Pharmacology and Experimental Therapeutics Jg. 335 (2010) Nr. 1, S. 2 - 12
ISSN: 0022-3565; 1521-0103Online Volltext: dx.doi.org/ (Open Access) -
Combined PER2 and CRY1 expression predicts outcome in chronic lymphocytic leukemiaIn: European Journal of Haematology Jg. 83 (2009) Nr. 4, S. 320 - 327
ISSN: 1600-0609Online Volltext: dx.doi.org/ -
Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression statusIn: Leukemia Jg. 20 (2006) Nr. 10, S. 1774 - 1782
ISSN: 0887-6924; 1476-5551Online Volltext: dx.doi.org/ -
A single nucleotide polymorphism of the transcription factor Growth Factor Independence 1 (GFI1) accelerates AML evolution and sensitizes AML cells to treatment with DNA repair inhibitors
Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020,In: Oncology Research and Treatment Jg. 43 (2020) Nr. Suppl. 4, S. 36 - 37
ISSN: 2296-5270; 2296-5262; 1423-0240; 0378-584XOnline Volltext: dx.doi.org/ -
Cisplatin-induced neuropathic pain is mediated by N-type voltage-gated calcium channelsIn: Acta Physiologica Jg. 216 (2016) Nr. Suppl. 707, Special Issue: Abstracts of the 95th Annual Meeting of the German Physiological Society, 3–5 March 2016, S. 87
ISSN: 1748-1708; 1748-1716Online Volltext: dx.doi.org/ -
Characterization of the stress response of normal rat kidney cells to platinating anticancer drugs and modulation by lipid lowering drugs
Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie e.V., 81th Annual Meeting, March 10 - 12, 2015, Kiel, Germany,In: Naunyn-Schmiedeberg's Archives of Pharmacology Jg. 388 (2015) Nr. Suppl.1, S. 66
ISSN: 0028-1298Online Volltext: dx.doi.org/ -
Oxaliplatin modulates voltage-gated calcium channel currents in small DRG neurons
94th Annual Meeting of the German Physiological Society, 5‐7 March 2015, Magdeburg, Germany,In: Acta Physiologica Jg. 213 (2015) Nr. Suppl. 699, S. 68
ISSN: 1748-1708; 1748-1716Online Volltext: dx.doi.org/ -
Subtype-dependent modulation of voltage-gated calcium channels in small dorsal root ganglion neurons by cisplatin
94th Annual Meeting of the German Physiological Society, 5‐7 March 2015, Magdeburg, Germany,In: Acta Physiologica Jg. 213 (2015) Nr. Suppl. 699, S. 69
ISSN: 1748-1708; 1748-1716 -
Prä-therapeutische ex-vivo Reparatur Kinetiken von Cisplatin-DNA-Addukten in Zirkulierenden Tumorzellen als Platin-Resistenz Test
119. Kongress der Deutschen Gesellschaft für Innere Medizin e.V., 06. - 09. April 2013, Wiesbaden,In: Der Internist Jg. 54 (2013) Nr. Suppl. 1, S. 95 - 96
ISSN: 0020-9554Online Volltext: dx.doi.org/ -
Functional characterization of ERCC1 isoforms in NSCLCIn: Cancer Research / AACR 102nd Annual Meeting 2011 ; Apr 2‐6, 2011, Orlando Jg. 71 (2011) Nr. 8, Suppl., S. 3895
ISSN: 0008-5472; 1538-7445Online Volltext: dx.doi.org/ -
Visualization and Quantitative Measurement of Drug-Induced Platinum Adducts in the Nuclear DNA of Individual Cells by an Immuno-Cytological AssayIn: Methods in Molecular Biology 2018, S. 351 - 358
ISBN: 978-1-4939-7233-3; 978-1-4939-7234-0 ISSN: 1064-3745Online Volltext: dx.doi.org/