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Innere Klinik (Tumorforschung)
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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
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A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in GlioblastomaIn: Clinical Cancer Research Jg. 29 (2023) Nr. 2, S. 488 - 500ISSN: 1557-3265; 1078-0432Online Volltext: dx.doi.org/ (Open Access)
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Decrypting drug actions and protein modifications by dose- and time-resolved proteomicsIn: Science Jg. 380 (2023) Nr. 6640, S. 93 - 101ISSN: 1095-9203; 0036-8075Online Volltext: dx.doi.org/
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Altered mitochondria functionality defines a metastatic cell state in lung cancer and creates an exploitable vulnerabilityIn: Cancer Research Jg. 81 (2021) Nr. 3, S. 567 - 579ISSN: 1538-7445; 0008-5472Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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HER2 mediates clinical resistance to the KRASG¹²C inhibitor sotorasib, which is overcome by co-targeting SHP2In: European Journal of Cancer (EJC) Jg. 159 (2021) S. 16 - 23ISSN: 1879-0852; 0959-8049; 1879-2995Online Volltext: dx.doi.org/
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Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasisIn: Cell Reports Jg. 37 (2021) Nr. 8,ISSN: 2211-1247Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Unraveling tumor heterogeneity by using DNA barcoding technologies to develop personalized treatment strategies in advanced-stage pdacIn: Cancers Jg. 13 (2021) Nr. 16,ISSN: 2072-6694Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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„Yes, we (s)can“ : Molekulare Barcodes in der Tumorforschung für neue in vivo-Screening VerfahrenIn: Unikate: Berichte aus Forschung und Lehre (2021) Nr. 56 : "Junge Wilde" - Die nächste Generation, S. 22 - 29ISSN: 0944-6060; 1869-3881Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Cancer cells stock up in lymph vessels to surviveIn: Nature Jg. 585 (2020) Nr. 7823, S. 36 - 37ISSN: 0028-0836; 1476-4687Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasisIn: Oncogenesis Jg. 9 (2020) Nr. 11, S. 102ISSN: 2157-9024Online Volltext: dx.doi.org/ (Open Access)
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Axon-like protrusions promote small cell lung cancer migration and metastasisIn: eLife Jg. 8 (2019) S. e50616ISSN: 2050-084XOnline Volltext: dx.doi.org/ (Open Access)
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Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistanceIn: Scientific Reports Jg. 8 (2018) Nr. 1, S. 14008ISSN: 2045-2322Online Volltext: dx.doi.org/ (Open Access)
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BLIMP1 induces transient metastatic heterogeneity in pancreatic cancerIn: Cancer Discovery Jg. 7 (2017) Nr. 10, S. 1184 - 1199ISSN: 2159-8290; 2159-8274Online Volltext: dx.doi.org/
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Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axisIn: Nature Medicine Jg. 23 (2017) Nr. 3, S. 291 - 300ISSN: 1546-170X; 1078-8956Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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An in vivo multiplexed small-molecule screening platformIn: Nature Methods Jg. 13 (2016) Nr. 10, S. 883 - 889ISSN: 1548-7105; 1548-7091Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Modeling therapy response and spatial tissue distribution of erlotinib in pancreatic cancerIn: Molecular Cancer Therapeutics Jg. 15 (2016) Nr. 5, S. 1145 - 1152ISSN: 1538-8514; 1535-7163Online Volltext: dx.doi.org/ (Open Access)
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Nfib Promotes Metastasis through a Widespread Increase in Chromatin AccessibilityIn: Cell Jg. 166 (2016) Nr. 2, S. 328 - 342ISSN: 0092-8674; 1097-4172Online Volltext: dx.doi.org/ (Open Access)
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Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editingIn: Genes and Development Jg. 29 (2015) Nr. 14, S. 1576 - 1585ISSN: 1549-5477; 0890-9369Online Volltext: dx.doi.org/ (Open Access)
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Identification of a Ninein (NIN) mutation in a family with spondyloepimetaphyseal dysplasia with joint laxity (leptodactylic type)-like phenotypeIn: Matrix Biology Jg. 32 (2013) Nr. 7-8, S. 387 - 392ISSN: 1569-1802; 0945-053XOnline Volltext: dx.doi.org/
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EGF Receptor Is Required for KRAS-Induced Pancreatic TumorigenesisIn: Cancer Cell Jg. 22 (2012) Nr. 3, S. 304 - 317ISSN: 1535-6108; 1878-3686Online Volltext: dx.doi.org/ (Open Access)
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MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancerIn: PLoS ONE Jg. 7 (2012) Nr. 6, S. e39424ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access)
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An inducible Tet-Off-H2B-GFP lentiviral reporter vector for detection and in vivo isolation of label-retaining cellsIn: Experimental Cell Research Jg. 316 (2010) Nr. 11, S. 1885 - 1895ISSN: 0014-4827; 1090-2422Online Volltext: dx.doi.org/
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Identification of epidermal pdx1 expression discloses different roles of notch1 and notch2 in murine krasG¹²D-induced skin carcinogenesis in vivoIn: PLoS ONE Jg. 5 (2010) Nr. 10, S. e13578ISSN: 1932-6203Online Volltext: dx.doi.org/ (Open Access)
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Combining Patient-Derived Xenografts and Barcoding Technology to Evaluate Response to Targeted Therapies in ALK+NSCLCIn: Journal of Thoracic Oncology Jg. 17 (2022) Nr. 9, S. 611ISSN: 1556-1380; 1556-0864Online Volltext: dx.doi.org/
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Targeting SHP2 Reverts Oncogenic Mediated Resistance to KRAS-G12C InhibitionIn: Journal of Thoracic Oncology Jg. 17 (2022) Nr. 9, S. S586 - S587ISSN: 1556-1380; 1556-0864Online Volltext: dx.doi.org/
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MA17.07 Identification of AHR as a Novel Regulator of Lung Cancer MetastasisIn: Journal of Thoracic Oncology Jg. 14 (2019) Nr. 10, Supplement, S. S319ISSN: 1556-1380; 1556-0864Online Volltext: dx.doi.org/ (Open Access)
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Multiplexed in vivo small molecule screening for immediate drug repositioning reveals novel therapeutic targets in metastatic pancreatic cancer
AACR Special Conference: Advances in Modeling Cancer in Mice: Technology, Biology, and Beyond; September 24-27, 2017; Orlando, Florida,In: Cancer Research Jg. 78 (2018) Nr. 10, S. 34 - 35ISSN: 1538-7445; 0008-5472 -
Barcoding Technology for Multiplexed Analysis of Metastatic Ability In VivoIn: Metastasis: Methods and Protocols / Stein, Ulrike S. (Hrsg.) 2021, S. 239 - 251ISBN: 978-1-0716-1350-4; 978-1-0716-1352-8; 978-1-0716-1349-8Online Volltext: dx.doi.org/