Publications
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Clinical and molecular characteristics associated with response to therapeutic PD-1/PD-L1 inhibition in advanced Merkel cell carcinomaIn: Journal for ImmunoTherapy of Cancer Vol. 10 (2022) Nr. 1,
ISSN: 2051-1426Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
DNA-methylation patterns imply a common cellular origin of virus- and UV-associated Merkel cell carcinomaIn: Oncogene Vol. 41 (2022) Nr. 1, pp. 37 - 45
ISSN: 0950-9232; 1476-5594Online Full Text: dx.doi.org/ (Open Access) -
HAMdetector : A Bayesian regression model that integrates information to detect HLA-associated mutationsIn: Bioinformatics Vol. 38 (2022) Nr. 9, pp. 2428 - 2436
ISSN: 1367-4803; 1460-2059; 1367-4811; 0266-7061Online Full Text: dx.doi.org/ -
A Pro-Inflammatory Gut Microbiome Characterizes SARS-CoV-2 Infected Patients and a Reduction in the Connectivity of an Anti-Inflammatory Bacterial Network Associates With Severe COVID-19In: Frontiers in Cellular and Infection Microbiology Vol. 11 (2021)
ISSN: 2235-2988Online Full Text: dx.doi.org/ (Open Access) -
BRAF and MEK inhibition in melanoma patients enables reprogramming of tumor infiltrating lymphocytesIn: Cancer Immunology, Immunotherapy Vol. 70 (2021) Nr. 6, pp. 1635 - 1647
ISSN: 1432-0851; 0340-7004Online Full Text: dx.doi.org/ (Open Access) -
Classical and Variant Merkel Cell Carcinoma Cell Lines Display Different Degrees of Neuroendocrine Differentiation and Epithelial-Mesenchymal TransitionIn: The Journal of Investigative Dermatology Vol. 141 (2021) Nr. 7, pp. 1675 - 1686.e4
ISSN: 1523-1747; 0022-202XOnline Full Text: dx.doi.org/ -
Classifier uncertainty : Evidence, potential impact, and probabilistic treatmentIn: PeerJ Computer Science Vol. 7 (2021) pp. e398
ISSN: 2376-5992Online Full Text: dx.doi.org/ (Open Access) -
Comprehensive Comparison of RNA-Seq Data of SARS-CoV-2, SARS-CoV and MERS-CoV Infections : Alternative Entry Routes and Innate Immune ResponsesIn: Frontiers in Immunology Vol. 12 (2021)
ISSN: 1664-3224Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Epigenetic mechanisms mediating cell state transitions in chondrocytesIn: Journal of Bone and Mineral Research (JBMR) Vol. 36 (2021) Nr. 5, pp. 968 - 985
ISSN: 0884-0431; 1523-4681Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Hepatitis B virus particles activate B cells through the TLR2–MyD88–mTOR axisIn: Cell Death and Disease Vol. 12 (2021) Nr. 1, pp. 34
ISSN: 2041-4889Online Full Text: dx.doi.org/ (Open Access) -
Human cord blood b cells differ from the adult counterpart by conserved ig repertoires and accelerated response dynamicsIn: Journal of Immunology Vol. 206 (2021) Nr. 12, pp. 2839 - 2851
ISSN: 1550-6606; 0022-1767Online Full Text: dx.doi.org/ -
Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic CellsIn: Frontiers in Immunology Vol. 11 (2021) pp. 607889
ISSN: 1664-3224Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Metabolism of cancer cells commonly responds to irradiation by a transient early mitochondrial shutdownIn: iScience Vol. 24 (2021) Nr. 11,
ISSN: 2589-0042Online Full Text: dx.doi.org/ (Open Access) -
Rhinovirus prevalence as indicator for efficacy of measures against SARS-CoV-2In: BMC Public Health Vol. 21 (2021) Nr. 1,
ISSN: 1471-2458Online Full Text: dx.doi.org/ (Open Access) -
Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications Vol. 12 (2021) Nr. 1, pp. 1505
ISSN: 2041-1723Online Full Text: dx.doi.org/ (Open Access) -
UMI or not UMI, that is the question for scRNA-seq zero-inflationIn: Nature Biotechnology Vol. 39 (2021) Nr. 2, pp. 158 - 159
ISSN: 1087-0156; 1546-1696; 0733-222XOnline Full Text: dx.doi.org/ -
Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances Vol. 10 (2020) Nr. 48, pp. 28711 - 28719
ISSN: 2046-2069Online Full Text: dx.doi.org/ (Open Access) -
Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances Vol. 10 (2020) Nr. 48, pp. 28711 - 28719
ISSN: 2046-2069Online Full Text: dx.doi.org/ (Open Access) -
An altered heparan sulfate structure in the articular cartilage protects against osteoarthritisIn: Osteoarthritis and Cartilage (2020)
ISSN: 1063-4584; 1522-9653Online Full Text: dx.doi.org/ (Open Access) -
An altered heparan sulfate structure in the articular cartilage protects against osteoarthritisIn: Osteoarthritis and Cartilage Vol. 28 (2020) Nr. 7, pp. 977 - 987
ISSN: 1522-9653; 1063-4584Online Full Text: dx.doi.org/ (Open Access) -
Bayesian Data Integration Questions Classic Study on Protease Self-Digest KineticsIn: ACS Omega Vol. 5 (2020) Nr. 25, pp. 15162 - 15168
ISSN: 2470-1343Online Full Text: dx.doi.org/ (Open Access) -
Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfateIn: Matrix Biology Vol. 39 (2020) pp. 43 - 59
ISSN: 1569-1802; 0945-053XOnline Full Text: dx.doi.org/ (Open Access) -
Excessive Neutrophils and Neutrophil Extracellular Traps in COVID-19In: Frontiers in Immunology Vol. 11 (2020)
ISSN: 1664-3224Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
IgGeneUsage : differential gene usage in immune repertoiresIn: Bioinformatics Vol. 36 (2020) Nr. 11, pp. 3590 - 3591
ISSN: 1367-4803; 1460-2059; 1367-4811; 0266-7061Online Full Text: dx.doi.org/ -
Predominance of Central Memory T Cells with High T-Cell Receptor Repertoire Diversity is Associated with Response to PD-1/PD-L1 Inhibition in Merkel Cell CarcinomaIn: Clinical Cancer Research Vol. 26 (2020) Nr. 9, pp. 2257 - 2267
ISSN: 1078-0432; 1557-3265Online Full Text: dx.doi.org/ (Open Access) -
Rapid uptake of pre-exposure prophylaxis (PrEP) after significant price reduction in Germany highlights importance of PrEP accessibilityIn: AIDS Research and Human Retroviruses (2020)
ISSN: 0889-2229; 1931-8405Online Full Text: dx.doi.org/ -
Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophyIn: Developmental Biology Vol. 457 (2020) Nr. 1, pp. 104 - 118
ISSN: 0012-1606; 1095-564XOnline Full Text: dx.doi.org/ (Open Access) -
intePareto : an R package for integrative analyses of RNA-Seq and ChIP-Seq data
International Conference on Intelligent Biology and Medicine (ICIBM 2020), 9.-10.08.2020, Virtual,In: BMC Genomics Vol. 21 (2020) Nr. Supplement 11, pp. 802
ISSN: 1471-2164Online Full Text: dx.doi.org/ (Open Access) -
A network of trans-cortical capillaries as mainstay for blood circulation in long bonesIn: Nature Metabolism Vol. 1 (2019) Nr. 2, pp. 236 - 250
ISSN: 2522-5812Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
A new class of supramolecular ligands stabilizes 14-3-3 protein-protein interactions by up to two orders of magnitudeIn: Chemical Communications: ChemComm Vol. 55 (2019) Nr. 1, pp. 111 - 114
ISSN: 1364-548X; 0009-241X; 0022-4936; 1359-7345Online Full Text: dx.doi.org/ -
Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bonesIn: PLoS ONE Vol. 14 (2019) Nr. 8, pp. e0218230
ISSN: 1932-6203 -
Differential escape of HCV from CD8⁺ T cell selection pressure between China and Germany depends on the presenting HLA class I moleculeIn: Journal of Viral Hepatitis Vol. 26 (2019) Nr. 1, pp. 73 - 82
ISSN: 1365-2893; 1352-0504Online Full Text: dx.doi.org/ (Open Access) -
Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart DiseaseIn: The journal of infectious diseases (JID) Vol. 219 (2019) Nr. 3, pp. 497 - 508
ISSN: 0022-1899; 1537-6613Online Full Text: dx.doi.org/ (Open Access) -
Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8⁺ T Cells and Evolve at the Population LevelIn: Gastroenterology Vol. 156 (2019) Nr. 6, pp. 1820 - 1833
ISSN: 0016-5085; 1528-0012Online Full Text: dx.doi.org/ (Open Access) -
Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly : Recent Advances and PerspectivesIn: ACS Infectious Diseases Vol. 5 (2019) Nr. 5, pp. 713 - 724
ISSN: 2373-8227Online Full Text: dx.doi.org/ -
Viral escape contributes to the failure of hepatitis D virus-specific CD8+ T-cells and drives evolution of HDVIn: Journal of Hepatology Vol. 70 (2019) Nr. Suppl. 1, pp. e21
ISSN: 0168-8278Online Full Text: dx.doi.org/ -
Amino acid substitutions within HLA-B*27- restricted T cell epitopes prevent recognition by hepatitis delta virus-specific CD8⁺ T cellsIn: Journal of Virology Vol. 92 (2018) Nr. 13, pp. e01891 - 17
ISSN: 1098-5514; 0022-538XOnline Full Text: dx.doi.org/ (Open Access) -
Biased IGH VDJ gene repertoire and clonal expansions in B cells of chronically hepatitis C virus–infected individualsIn: Blood Vol. 131 (2018) Nr. 5, pp. 546 - 557
ISSN: 1528-0020; 0006-4971Online Full Text: dx.doi.org/ (Open Access) -
Evaluation of susceptibility of HIV-1 CRF01_AE variants to neutralization by a panel of broadly neutralizing antibodiesIn: Archives of Virology Vol. 163 (2018) Nr. 12, pp. 3303 - 3315
ISSN: 0304-8608Online Full Text: dx.doi.org/ -
Illumina sequencing for the identification of filamentous bulking and foaming bacteria in industrial activated sludge plantsIn: International Journal of Environmental Science and Technology Vol. 15 (2018) Nr. 6, pp. 1139 - 1158
ISSN: 1735-2630; 1735-1472Online Full Text: dx.doi.org/ -
Locating Large, Flexible Ligands on ProteinsIn: Journal of Chemical Information and Modeling Vol. 58 (2018) Nr. 2, pp. 315 - 327
ISSN: 1549-9596; 1520-5142; 0021-9576; 0095-2338Online Full Text: dx.doi.org/ (Open Access) -
Proteolytic processing of palmitoylated Hedgehog peptides specifies the 3-4 intervein region of the Drosophila wingIn: eLife Vol. 7 (2018) pp. e33033
ISSN: 2050-084XOnline Full Text: dx.doi.org/ (Open Access) -
Rational Design, Binding Studies, and Crystal-Structure Evaluation of the First Ligand Targeting the Dimerization Interface of the 14-3-3ζ Adapter ProteinIn: ChemBioChem Vol. 19 (2018) Nr. 6, pp. 591 - 595
ISSN: 1439-4227; 1439-7633Online Full Text: dx.doi.org/ -
Signaling systems affecting the severity of multiple osteochondromasIn: Bone: Official Journal of the International Bone and Mineral Society (IBMS) Vol. 111 (2018) pp. 71 - 81
ISSN: 1873-2763; 8756-3282Online Full Text: dx.doi.org/ (Open Access) -
Trade-off shapes diversity in eco-evolutionary dynamicsIn: eLife Vol. 7 (2018) pp. e36273
ISSN: 2050-084XOnline Full Text: dx.doi.org/ (Open Access) -
Ca2+ coordination controls sonic hedgehog structure and its Scube2-regulated releaseIn: Journal of Cell Science Vol. 130 (2017) Nr. 19, pp. 3261 - 3271
ISSN: 0021-9533; 1477-9137Online Full Text: dx.doi.org/ (Open Access) -
Granulocytic myeloid-derived suppressor cells suppress virus-specific CD8+ T cell responses during acute Friend retrovirus infectionIn: Retrovirology Vol. 14 (2017)
ISSN: 1742-4690Online Full Text: dx.doi.org/ (Open Access) -
Quantitative Assessment of Molecular Dynamics Sampling for Flexible SystemsIn: Jounal of Chemical Theory and Computation Vol. 13 (2017) Nr. 2, pp. 400 - 414
ISSN: 1549-9618; 1549-9626Online Full Text: dx.doi.org/ -
Quantitative Comparison of Abundance Structures of Generalized Communities : from B-Cell Receptor Repertoires to MicrobiomesIn: PLoS Computational Biology Vol. 13 (2017) Nr. 1,
ISSN: 1553-734X; 1553-7358Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Role of Gag mutations in PI resistance in the Swiss HIV cohort study : bystanders or contributors?In: Journal of Antimicrobial Chemotherapy Vol. 72 (2017) Nr. 3, pp. 866 - 875
ISSN: 0305-7453; 1460-2091Online Full Text: dx.doi.org/ (Open Access) -
Protistan community analysis : key findings of a large scale molecular samplingIn: ISME Journal Vol. 10 (2016) pp. 2269 - 2279
ISSN: 1751-7370; 1751-7362Online Full Text: dx.doi.org/ (Open Access) -
SeqFeatR for the Discovery of Feature-Sequence AssociationsIn: PLoS ONE Vol. 11 (2016) Nr. 1, pp. e0146409
ISSN: 1932-6203Online Full Text: dx.doi.org/ (Open Access) -
Adaptation of the Hepatitis B Virus Core Protein to CD8+ T-Cell Selection PressureIn: Hepatology Vol. 62 (2015) Nr. 1, pp. 47 - 56
ISSN: 0270-9139Online Full Text: dx.doi.org/ (Open Access) -
AmpliconDuo : a split-sample filtering protocol for high-throughput amplicon sequencing of microbial communitiesIn: PLoS ONE Vol. 10 (2015) Nr. 11, pp. e0141590
ISSN: 1932-6203Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Complexity of the human memory B-cell compartment is determined by the versatility of clonal diversification in germinal centersIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 112 (2015) Nr. 38, pp. E5281 - E5289
ISSN: 1091-6490; 0027-8424Online Full Text: dx.doi.org/ (Open Access) -
Parameters influencing baseline HIV-1 genotypic tropism testing related to clinical outcome in patients on maravirocIn: PLoS ONE Vol. 10 (2015) Nr. 5, pp. e0125502
ISSN: 1932-6203Online Full Text: dx.doi.org/ (Open Access) -
Pareto optimization identifies diverse set of phosphorylation signatures predicting response to treatment with dasatinibIn: PLoS ONE Vol. 10 (2015) Nr. 6, pp. e0128542
ISSN: 1932-6203Online Full Text: dx.doi.org/ (Open Access) -
Virus-induced type i interferon deteriorates control of systemic pseudomonas aeruginosa infectionIn: Cellular Physiology and Biochemistry Vol. 36 (2015) Nr. 6, pp. 2379 - 2392
ISSN: 1015-8987; 1421-9778Online Full Text: dx.doi.org/ (Open Access) -
A simple structure-based model for the prediction of HIV-1 co-receptor tropismIn: BioData Mining Vol. 7 (2014) pp. 14
ISSN: 1756-0381Online Full Text: dx.doi.org/ (Open Access) -
Differential selection in HIV-1 gp120 between subtype B and East Asian variant B'In: Virologica Sinica Vol. 29 (2014) Nr. 1, pp. 40 - 47
ISSN: 1674-0769; 1995-820XOnline Full Text: dx.doi.org/ -
HLA-B*27 is protective against HCV genotype 1 and 3 and associated with targeting of distinct genotype-specific CD8(+) cell epitopesIn: Journal of Hepatology Vol. 60 (2014) Nr. Suppl. 1, pp. 140
ISSN: 0168-8278Online Full Text: dx.doi.org/ -
Identification of Significant Features by the Global Mean Rank TestIn: PLoS ONE Vol. 9 (2014) Nr. 8, pp. e104504
ISSN: 1932-6203Online Full Text: dx.doi.org/ (Open Access) -
Signaling Domain of Sonic Hedgehog as Cannibalistic Calcium-Regulated Zinc-PeptidaseIn: PLoS Computational Biology Vol. 10 (2014) Nr. 7, pp. e1003707
ISSN: 1553-7358; 1553-734XOnline Full Text: dx.doi.org/ (Open Access) -
A Small Set of Succinct Signature Patterns Distinguishes Chinese and Non-Chinese HIV-1 GenomesIn: PLoS ONE Vol. 8 (2013) Nr. 3, pp. e58804
ISSN: 1932-6203Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
A new approach to inhibit human β-tryptase by protein surface binding of four-armed peptide ligands with two different sets of armsIn: Organic and Biomolecular Chemistry Vol. 11 (2013) Nr. 10, pp. 1631 - 1639
ISSN: 1477-0539; 1477-0520Online Full Text: dx.doi.org/ -
Correction: A Small Set of Succinct Signature Patterns Distinguishes Chinese and Non-Chinese HIV-1 Genomes.In: PLoS ONE Vol. 8 (2013) Nr. 12,
ISSN: 1932-6203Online Full Text: dx.doi.org/ (Open Access) -
Design of a Modular Protein-Based MRI Contrast Agent for Targeted ApplicationIn: PLoS ONE Vol. 8 (2013) Nr. 6, pp. e65346
ISSN: 1932-6203Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Inference of global HIV-1 sequence patterns and preliminary feature analysisIn: Virologica Sinica Vol. 28 (2013) Nr. 4, pp. 228 - 238
ISSN: 1674-0769; 1995-820XOnline Full Text: dx.doi.org/ -
Novel Algorithm for Non-Invasive Assessment of Fibrosis in NAFLDIn: PLoS ONE Vol. 8 (2013) Nr. 4, pp. e62439
ISSN: 1932-6203Online Full Text: dx.doi.org/ (Open Access) -
The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovirIn: Antiviral Research Vol. 97 (2013) Nr. 2, pp. 93 - 100
ISSN: 0166-3542; 1872-9096Online Full Text: dx.doi.org/ -
Transient domain interactions enhance the affinity of the mitotic regulator pin1 toward phosphorylated peptide ligandsIn: Structure Vol. 21 (2013) Nr. 10, pp. 1769 - 1777
ISSN: 1878-4186Online Full Text: dx.doi.org/ (Open Access) -
An emerging role of sonic hedgehog shedding as a modulator of heparan sulfate interactionsIn: The Journal of Biological Chemistry (JBC) Vol. 287 (2012) Nr. 52, pp. 43708 - 43719
ISSN: 0021-9258; 1083-351XOnline Full Text: dx.doi.org/ -
Escape from a dominant hla-b*15-restricted cd8+ t cell response against hepatitis c virus requires compensatory mutations outside the epitopeIn: Journal of Virology Vol. 86 (2012) Nr. 2, pp. 991 - 1000
ISSN: 0022-538X; 1098-5514Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
The Normal-Mode Entropy in the MM/GBSA Method : Effect of System Truncation, Buffer Region, and Dielectric ConstantIn: Journal of Chemical Information and Modeling Vol. 52 (2012) Nr. 8, pp. 2079 - 2088
ISSN: 1549-9596; 1520-5142; 0021-9576; 0095-2338Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
The imprinted NPAP1/C15orf2 gene in the Prader-Willi syndrome region encodes a nuclear pore complex associated proteinIn: Human Molecular Genetics Vol. 21 (2012) Nr. 18, pp. 4038 - 4048
ISSN: 1460-2083; 0964-6906Online Full Text: dx.doi.org/ (Open Access) -
An additional glucose dehydrogenase from Sulfolobus solfataricus : fine-tuning of sugar degradation?In: Biochemical Society Transactions Vol. 39 (2011) Nr. 1, pp. 77 - 81
ISSN: 0300-5127; 1470-8752Online Full Text: dx.doi.org/ -
Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptidesIn: Nature Communications Vol. 2 (2011) pp. 453
ISSN: 2041-1723Online Full Text: dx.doi.org/ (Open Access) -
CD8+ T-Cell Response Promotes Evolution of Hepatitis C Virus Nonstructural ProteinsIn: Gastroenterology Vol. 140 (2011) Nr. 7, pp. 2064 - 2073
ISSN: 0016-5085Online Full Text: dx.doi.org/ -
Improved Bevirimat resistance prediction by combination of structural and sequence-based classifiersIn: BioData Mining Vol. 4 (2011) Nr. 1, pp. 26
ISSN: 1756-0381Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Interpol : An R package for preprocessing of protein sequencesIn: BioData Mining Vol. 4 (2011) pp. 16
ISSN: 1756-0381Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Machine learning on normalized protein sequencesIn: BMC Research Notes Vol. 4 (2011) pp. 94
ISSN: 1756-0500Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Parental origin and functional relevance of a de novo UBE3A variantIn: European Journal of Medical Genetics (EJMG) Vol. 54 (2011) Nr. 1, pp. 19 - 24
ISSN: 1878-0849; 1769-7212Online Full Text: dx.doi.org/ -
Single-Domain Parvulins Constitute a Specific Marker for Recently Proposed Deep-Branching Archaeal SubgroupsIn: Evolutionary Bioinformatics Vol. 7 (2011) pp. 135 - 148
ISSN: 1176-9343Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Sonic hedgehog shedding results in functional activation of the solubilized proteinIn: Developmental Cell Vol. 20 (2011) Nr. 6, pp. 764 - 774
ISSN: 1534-5807; 1878-1551Online Full Text: dx.doi.org/ (Open Access) -
Estimating affinities of calcium ions to proteinsIn: Advances and Applications in Bioinformatics and Chemistry Vol. 3 (2010) Nr. 1, pp. 1 - 6
ISSN: 1178-6949Online Full Text: dx.doi.org/ (Open Access) -
Predicting Bevirimat resistance of HIV-1 from genotypeIn: BMC Bioinformatics Vol. 11 (2010) pp. 37
ISSN: 1471-2105Online Full Text: dx.doi.org/ (Open Access) -
Prediction of Co-Receptor Usage of HIV-1 from GenotypeIn: PLoS Computational Biology Vol. 6 (2010) Nr. 4, pp. e1000743
ISSN: 1553-7358; 1553-734XOnline Full Text: dx.doi.org/ (Open Access) -
Rpd3-dependent boundary formation at telomeres by removal of Sir2 substrateIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 107 (2010) Nr. 12, pp. 5522 - 5527
ISSN: 1091-6490; 0027-8424Online Full Text: dx.doi.org/ -
Structure of HIV-1 quasi-species as early indicator for switches of co-receptor tropism.In: AIDS Research and Therapy Vol. 7 (2010) pp. 41
ISSN: 1742-6405Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
The antiretroviral potency of emtricitabine is approximately 3-fold higher compared to lamivudine in dual human immunodeficiency virus type 1 infection/competition experiments in vitroIn: Antiviral Research Vol. 86 (2010) Nr. 3, pp. 312 - 315
ISSN: 1872-9096Online Full Text: dx.doi.org/ -
Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60In: Chromosoma Vol. 119 (2010) Nr. 1, pp. 99 - 113
ISSN: 0009-5915; 1432-0886Online Full Text: dx.doi.org/ -
A novel algorithm for macromolecular epitope matchingIn: Algorithms Vol. 2 (2009) Nr. 1, pp. 498 - 517
ISSN: 1999-4893Online Full Text: dx.doi.org/ -
Prevalence of C-terminal gag cleavage site mutations in HIV from therapy-naïve patientsIn: Journal of Infection Vol. 58 (2009) Nr. 1, pp. 61 - 67
ISSN: 0163-4453Online Full Text: dx.doi.org/ -
Prevalence of minor variants of HIV strains at reverse transcriptase position 103 in therapy-naïve patients and their impact on the virological failureIn: Journal of Clinical Virology Vol. 45 (2009) Nr. 1, pp. 34 - 38
ISSN: 1386-6532Online Full Text: dx.doi.org/ -
Biallelic loss of function of the promyelocytic leukaemia zinc finger (PLZF) gene causes severe skeletal defects and genital hypoplasiaIn: Journal of Medical Genetics Vol. 45 (2008) Nr. 11, pp. 731 - 737
ISSN: 1468-6244; 0022-2593Online Full Text: dx.doi.org/ -
Evolution : von der Biologie zur Mathematik und wieder zurück ; die Ergebnisse der Evolutionstheorie sind heute nicht nur Naturbeschreibung, sondern auch mathematisches WerkzeugIn: Unikate: Berichte aus Forschung und Lehre (2008) Nr. 33: Mathematik: eine lebendige Wissenschaft, pp. 54 - 65
ISSN: 0944-6060; 0941-746X; 1869-3881Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Evolutionary Pareto-optimization of stably folding peptidesIn: BMC Bioinformatics Vol. 9 (2008) pp. 109
ISSN: 1471-2105Online Full Text: dx.doi.org/ (Open Access) -
The B-cell epitope of the monoclonal anti-factor VIII anti- body ESH8 characterized by peptide array analysisIn: Thrombosis and Haemostasis Vol. 99 (2008) Nr. 3, pp. 634 - 637
ISSN: 0340-6245; 2567-689XOnline Full Text: dx.doi.org/ -
A multiobjective evolutionary method for the design of peptidic mimotopesIn: Journal of Computational Biology Vol. 13 (2006) Nr. 1, pp. 113 - 125
ISSN: 1066-5277; 1557-8666Online Full Text: dx.doi.org/ -
Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients.In: Antiviral Therapy Vol. 11 (2006) Nr. 7, pp. 879 - 887
ISSN: 2040-2058 -
SearchXLinks : A program for the identification of disulfide bonds in proteins from mass spectraIn: Analytical Chemistry Vol. 78 (2006) Nr. 4, pp. 1235 - 1241
ISSN: 1520-6882; 0003-2700Online Full Text: dx.doi.org/ -
The enzyme-binding region of human GM2-activator proteinIn: The FEBS Journal Vol. 273 (2006) Nr. 5, pp. 982 - 991
ISSN: 1742-4658; 1742-464XOnline Full Text: dx.doi.org/ -
Computational methods for the design of effective therapies against drug resistant HIV strainsIn: Bioinformatics Vol. 21 (2005) Nr. 21, pp. 3943 - 3950
ISSN: 1367-4803; 1460-2059; 1367-4811; 0266-7061Online Full Text: dx.doi.org/ (Open Access) -
Estimating HIV evolutionary pathways and the genetic barrier to drug resistanceIn: Journal of Infectious Diseases Vol. 191 (2005) Nr. 11, pp. 1953 - 1960
ISSN: 0022-1899Online Full Text: dx.doi.org/ (Open Access) -
Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapyIn: Journal of Clinical Virology Vol. 34 (2005) Nr. 4, pp. 277 - 287
ISSN: 1873-5967; 1386-6532Online Full Text: dx.doi.org/ -
Learning multiple evolutionary pathways from cross-sectional dataIn: Journal of Computational Biology Vol. 12 (2005) Nr. 6, pp. 584 - 598
ISSN: 1066-5277Online Full Text: dx.doi.org/ -
Mtreemix : A software package for learning and using mixture models of mutagenetic treesIn: Bioinformatics Vol. 21 (2005) Nr. 9, pp. 2106 - 2107
ISSN: 1367-4803; 1460-2059; 1367-4811; 0266-7061Online Full Text: dx.doi.org/ (Open Access) -
Photoaffinity labelling of the Human GM2-activator protein Mechanistic insight into ganglioside GM2 degradationIn: European Journal of Biochemistry: the FEBS journal Vol. 271 (2004) Nr. 3, pp. 614 - 627
ISSN: 0014-2956Online Full Text: dx.doi.org/ -
Geno2pheno : Estimating phenotypic drug resistance from HIV-1 genotypesIn: Nucleic Acids Research Vol. 31 (2003) Nr. 13, pp. 3850 - 3855
ISSN: 1362-4962; 0301-5610; 0305-1048Online Full Text: dx.doi.org/ -
Methods for optimizing antiviral combination therapiesIn: Bioinformatics Vol. 19 (2003) Nr. Suppl 1, pp. i16 - i25
ISSN: 1367-4803; 1460-2059; 1367-4811; 0266-7061Online Full Text: dx.doi.org/ (Open Access) -
Structural modeling of ataxin-3 reveals distant homology to adaptinsIn: Proteins: Structure, Function and Genetics Vol. 50 (2003) Nr. 2, pp. 355 - 370
ISSN: 0887-3585Online Full Text: dx.doi.org/ -
Tenofovir Resistance and ResensitizationIn: Antimicrobial Agents and Chemotherapy Vol. 47 (2003) Nr. 11, pp. 3478 - 3484
ISSN: 0066-4804Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Diversity and complexity of HIV-1 drug resistance: A bioinformatics approach to predicting phenotype from genotypeIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 99 (2002) Nr. 12, pp. 8271 - 8276
ISSN: 1091-6490; 0027-8424Online Full Text: dx.doi.org/ -
Partial reduction and two-step modification of proteins for identification of disulfide bondsIn: Analytical Chemistry Vol. 74 (2002) Nr. 10, pp. 2386 - 2393
ISSN: 1520-6882; 0003-2700Online Full Text: dx.doi.org/ -
Screening for disulfide bonds in proteins by MALDI in-source decay and LIFT-TOF/TOF-MSIn: Analytical Chemistry Vol. 74 (2002) Nr. 19, pp. 4980 - 4988
ISSN: 1520-6882; 0003-2700Online Full Text: dx.doi.org/ -
Web Site : The Protein Information ResourceIn: Angewandte Chemie International Edition Vol. 41 (2002) Nr. 6, pp. 1075 - 1075
ISSN: 1521-3773; 0570-0833Online Full Text: dx.doi.org/ -
Geno2pheno : Interpreting Genotypic HIV Drug Resistance TestsIn: IEEE Intelligent Systems Vol. 16 (2001) Nr. 6, pp. 35 - 41
ISSN: 1941-1294; 1541-1672Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Neue Wege zur Optimierung von Anti-HIV-Therapien : Erste Analysen mit bioinformatischen MethodenIn: BIOforum Vol. 24 (2001) Nr. 12, pp. 912 - 914
ISSN: 0940-0079 -
Band-flip and kink as novel structural motifs in α-(1→4)-D-glucose oligosaccharides. Crystal structures of cyclodeca- and cyclotetradecaamyloseIn: Carbohydrate Research Vol. 322 (1999) Nr. 3-4, pp. 228 - 246
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Simulation of oligopeptide folding or how do residues talkIn: AIP Conference Proceedings Vol. 487 (1999) Nr. 1, pp. 54 - 68
ISSN: 1551-7616; 0094-243XOnline Full Text: dx.doi.org/ -
Two-Stage Method for Protein-Ligand DockinIn: (J. Med. Chem.) Vol. 42 (1999) pp. 4422 - 4433
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Two-stage method for protein-ligand dockingIn: Journal of Medicinal Chemistry Vol. 42 (1999) Nr. 21, pp. 4422 - 4433
ISSN: 0022-2623; 1943-2992; 0095-9065; 1520-4804Online Full Text: dx.doi.org/ -
A structural role for glycosylation : Lessons from the hp modelIn: Folding and Design Vol. 3 (1998) Nr. 5, pp. 337 - 343
ISSN: 1878-5808; 1359-0278Online Full Text: dx.doi.org/ (Open Access) -
A structural role for glycosylation: lessons from the hp-modeIn: Folding & Design Vol. 3 (1998) pp. 337 - 343
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Strain-Induced “Band Flips” in Cyclodecaamylose and Higher HomologuesIn: Angewandte Chemie International Edition Vol. 37 (1998) Nr. 5,
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Structures of the Common Cyclodextrins and Their Larger Analogues -- Beyond the DoughnuIn: Chemical Reviews Vol. 98 (1998) pp. 1787 - 1802
ISSN: 1520-6890; 0009-2665 -
Structures of the common cyclodextrins and their larger analogues : beyond the doughnutIn: Chemical Reviews Vol. 98 (1998) Nr. 5, pp. 1787 - 1802
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Folding Pathways of a Helix-Turn-Helix Model ProteinIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Vol. 101 (1997) Nr. 34, pp. 6734 - 6740
ISSN: 1520-6106; 1520-5207Online Full Text: dx.doi.org/ (Open Access) -
Polypeptide folding with-off lattice Monte Carlo dynamics : The methodIn: European Biophysics Journal Vol. 24 (1996) Nr. 6, pp. 387 - 403
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Protein dynamics with off-lattice monte carlo movesIn: Physical Review E: Statistical, nonlinear, and soft matter physics Vol. 53 (1996) Nr. 4, pp. 4221 - 4224
ISSN: 1095-3787Online Full Text: dx.doi.org/ (Open Access) -
Arevir : A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIVIn: Data Integration in the Life Sciences / Third International Workshop (DILS), July 20-22, 2006, Hinxton, UK, / Leser, Ulf; Naumann, Felix; Eckman, Barbara (Eds.) 2006, pp. 185 - 194
ISBN: 978-3-540-36593-8Online Full Text: dx.doi.org/ -
A multi-objective evolutionary approach to peptide structure redesign and stabilizationIn: Proceedings of the 7th annual conference on Genetic and evolutionary computation / GECCO 2005 - Genetic and Evolutionary Computation Conference, 25-29 June 2005, Washington D.C., United States / Beyer, Hans-Georg (Eds.) 2005, pp. 423 - 429
ISBN: 1-59593-010-8Online Full Text: dx.doi.org/ -
Characterization of Novel HIV Drug Resistance Mutations Using Clustering, Multidimensional Scaling and SVM-Based Feature RankingIn: Knowledge Discovery in Databases: PKDD 2005: th European Conference on Principles and Practice of Knowledge Discovery in Databases, Porto, Portugal, October 3-7, 2005. Proceedings / 9th European Conference on Principles and Practice of Knowledge Discovery in Databases (PKDD 2005), 3-7 October 2005, Porto, Portugal / Jorge, Alípio Mário; Torgo, Luís; Brazdil, Pavel; Camacho, Rui; Gama, João (Eds.) 2005, pp. 285 - 296
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Computergestützte molekulare Modellierung für die Suche nach neuen Wirkstoffen gegen HIV/AIDSIn: Resistenz in der HIV-Therapie: Diagnostik und Management / Oette, Mark; Kaiser, Rolf; Häussinger, Dieter (Eds.) 2003, pp. 62 - 65
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A New Method for the Fast Solution of Protein-3D-Structures, combining Experiments and BioinformaticsIn: Coupling of biological and electronic systems: proceedings of the 2nd caesarium, Bonn, November 1-3, 2000 / Hoffmann, K.H. (Eds.) 2002, pp. 59 - 78
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Identifying Drug Resistance-Associated Patterns in HIV GenotypesIn: Computer science and biology: proceedings of the German Conference on Bioinformatics / German Conference on Bioinformatics (GCB '01), 7.-10. October 2001, Braunschweig / Wingender, Edgar (Eds.) 2001, pp. 126 - 130
ISBN: 978-3-00-008114-9 -
Tackling Concrete Problems in Molecular Biophysics Using Monte Carlo and Related Methods : Glycosylation, Folding, SolvationIn: Workshop on Monte Carlo Approach to Biopolymers and Protein Folding / Workshop on Monte Carlo Approach to Biopolymers and Protein, 3 - 5 December 1997 , Jülich, Germany / Grassberger, P.; Barkema, G.; Nadler, W. (Eds.) 1998, pp. 153 - 170
ISBN: 981-02-3658-1 -
A Monte Carlo method for simulations of protein folding with detailed protein modelsIn: Perspectives on protein engineering: a comprehensive on-line access tool for Web-based resources, papers from Perspectives on Protein Engineering '96 / Perspectives on Protein Engineering Conference 5 (POPE5), 2-6 March 1996, Montpellier 1996
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Monte Carlo Methoden zur Simulation der Langzeitdynamik von ProteinenBerlin (1996) 115 Seiten
(Bioinformatik)ISBN: 978-3-89574-150-0 -
Monte Carlo Methoden zur Simulation der Langzeitdynamik von Proteinen : BioinformatikBerlin (1996)
ISBN: 3-89574-150-7