Publikationen 2018

169. M. H. Vaquero, D. Bouquio, M. Kallab, K. Biggs, G. Nair, J. Ochoa, W. Poewe, G. K. Wenning, F.-G. Klärner, T. Schrader, G. Bitan, N. Stefanova. The molecular tweezer CLR01 ameliorates the pathological phenotype in a transgenic model of multiple system atrophy. Submitted to Molecular Neurodegeneration 2018.

168. Ravinder Malik, Helen Meng, Christine Fontanilla, Piriya Wongkongkathep, Christian Corrales, Niki Sepanj, Ryan Atlasi, Frank-Gerrit Klärner, Thomas Schrader, Melissa Spencer, Joseph Loo, Martina Wiedau, and Gal Bitan: The molecular tweezer CLR01 inhibits aberrant SOD1 self-assembly in vitro and in the G93A-SOD1 mouse model of ALS. Submitted to J. Biol. Chem. 2018.

167. Bisphosphonate Ligand Mediated Ultrasensitive Capacitive Protein Sensor: Complementary Match of Supramolecular and Dynamic Chemistry. G. Ertürk, M. Akhoundian, K. Kujawski ,S. Shinde, S. Yee Yeung, M. Hedström, T. Schrader, B. Mattiasson, B. Sellergren. Accepted by New J. Chem.

166. S. Gadre, M. S. Peters, A. Serrano, T. Schrader: A Synthetic Methodology Toward Pyrrolo[2,3‑b]pyridones for GC Base Pair Recognition. Org. Lett. 2018, ASAP DOI: 10.1021/acs.orglett.8b03111.

165. Michael Nshanian; Carter Lantz; Piriya Wongkongkathep; Thomas Schrader; Frank-Gerrit Klärner; Anika Blümke; Clément Despres; Michael Ehrmann; Caroline Smet-Nocca; Gal Bitan; Joseph A. Loo: Native Top-Down Mass Spectrometry and Ion Mobility Spectrometry of the Interaction of Tau Protein with a Molecular Tweezer Assembly Modulator. J. Am. Soc. Mass Spectr. (JASMS) 2018, DOI: 10.1007/s13361-018-2027-6.

164. Provisional Patent Application UCLAP204US/UC-2018-906-1-LA „New Molecular Tweezers against Neurological Disorders and Viral Infections“. Inventors: G. Bitan, T. Schrader, J. Münch, C. Heid, A. Sowislok, A. Röcker, D. Bouquio, R. Malik.

163. K. Kujawski, C. Heid, T. Schrader. Maßgeschneiderte Liganden für Protein-Protein-Interaktionen. BIOspektrum 2018, 24, 387-389, Springer. DOI: 10.1007/s12268-018-0934-5.

162. Christian Heid, Andrea Sowislok, Torsten Schaller, Felix Niemeyer, Frank-Gerrit Klärner, Thomas Schrader. Molecular Tweezers with Additional Recognition Sites. Chem. Eur. J. 2018, 44, 11332-11343.

161. Ravinder Malik, Jing Di, Gayatri Nair, Aida Attar, Karen Taylor, Edmond Teng, Frank-Gerrit Klärner, Thomas Schrader, and Gal Bitan. Using Molecular Tweezers to Remodel Abnormal Protein Self-Assembly and Inhibit the Toxicity of Amyloidogenic Proteins. In: Bradley L. Nilsson and Todd M. Doran (eds.), Peptide Self-Assembly: Methods and Protocols, Methods in Molecular Biology 2018, vol. 1777, Chapter 24, 369-386. Humana Press, New York, NY.

160. Cell entry of a host-targeting protein of oomycetes requires gp96. Franziska Trusch, Lars Loebach, Stephan Wawra, Elaine Durward, Andreas Wuensch, Irene de Bruijn, Kevin MacKenzie, Ariane Willems, Aleksandra D. Toloczko, Javier Diéguez-Uribeondo, Tim Rasmussen, Thomas Schrader, Peter Bayer, Chris J. Secombes, Pieter van West, Nature Communications 2018, 9, 2347-2358.

Publikationen 2017

159. Inhibition of Mutant aB Crystallin-Induced Protein Aggregation by a Molecular Tweezer.  N. Xu, G. Bitan, T.omas Schrader, F.-G. Klärner, H. Osinska, J. Robbins, J. Am. Heart Assoc. 2017, 6, e006182.

158. Affinity Copolymers Inhibit Digestive Enzymes by Surface Recognition. Patrick Gilles, Kirstin Wenck, Inga Stratmann, Michael Kirsch, Daniel A. Smolin, Torsten Schaller, Herbert de Groot, Arno Kraft, Thomas Schrader - ACS Biomacromolecules 2017, 18, 1772–1784.

157. A molecular tweezer ameliorates motor deficits in mice over-expressing α-synuclein. F. Richter, S. Subramaniam, I. Magen, P. Lee, J. Hayes, A. Attar, C. Zhu, N. Franich, N. Bove, K. De La Rosa, J. Kwong, F.-G. Klärner, T. Schrader, M.- F. Chesselet, G. Bitan, Neurotherapeutics 2017, 14, 1107-1119.

156. An NMR Method to Pinpoint Supramolecular Binding to Basic Amino Acids on Proteins. Anna Hogeweg, Andrea Sowislok, Thomas Schrader, Christine Beuck, Angew. Chem. Int. Ed. 2017, 56, 14758 –14762.

155. Cucurbit[8]uril and 14-3-3 based binary bivalent supramolecular-protein assembly platform and co-crystal structure. Pim J. de Vink, Jeroen M. Briels, Thomas Schrader, Lech-Gustav Milroy, Luc Brunsveld, Christian Ottmann, Angew. Chem. Int. Ed. 2017, 56, 8998–9002.

154. The molecular tweezer CLR01 stabilizes a disordered protein-protein interface. David Bier, Sumit Mittal, Kenny Bravo-Rodriguez,  Andrea Sowislok, Jeroen Briels, Christian Heid, Maria Bartel, Burkhard Wettig, Luc Brunsveld, Elsa Sanchez-Garcia, Thomas Schrader, Christian Ottmann, J. Am. Chem. Soc. 2017, 139, 16256-16263.

153. Inhibition of Huntingtin exon-1 aggregation by the molecular tweezer CLR01, Sumit Mittal, Tobias Vöpel, Shivang Vachharajani, Kenny Bravo-Rodriguez, Abhishek Sharma, Anne Steinhof, Frank-Gerrit Klärner, Thomas Schrader, Gal Bitan, Erich E. Wanker, Simon Ebbinghaus and Elsa Sanchez-Garcia, J. Am. Chem. Soc. 2017, 139, 5640–5643.

152. Molecular tweezers inhibit PARP-1 by a new Mechanism. Constanze Wilch, Peter Talbiersky, Utta Berchner-Pfannschmidt, Torsten Schaller, Michael Kirsch, Frank-Gerrit Klärner, Thomas Schrader, Eur. J. Org. Chem. 2017, 16, 2223–2229.

Publikationen   2016

151. Neurotoxicity of the Parkinson Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos. A. Lulla, L. Barnhill, G. Bitan, M. I. Ivanova, B. Nguyen, K. O'Donnell, M. C. Stahl, C. Yamashiro, F.-G. Klärner, T. Schrader, A. Sagasti, J. M. Bronstein, Environ. Health Perspect. 2016, 124, 1766-1775.

150. Molecular tweezers target a protein–protein interface and thereby modulate complex formation. F. Trusch, K. Kowski, K. Bravo-Rodriguez, C. Beuck, A. Sowislok, B. Wettig, A. Matena, E. Sanchez-Garcia, H. Meyer, T. Schrader and P. Bayer, Chem. Commun. 2016, 52, 14141-14144.

149. Calix[n]arenes and Nucleic Acids. M. S. Peters, T. Schrader, Chapter in “Calixarenes and Beyond - Calixarene Functionalization and Applications”, P. Neri, J. Sessler, M.-X. Wang, editors, Springer, Cham, 2016.

148. Molecular tweezers for lysine and arginine – powerful inhibitors of pathologic protein aggregation. T. Schrader, G. Bitan, F.-G. Klärner, Chem. Commun. 2016, 52, 11318-11334.

147. Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells. L. Ippolitto, A. Marini, L. Cavallini, A. Morandi, L. Pietrovito, G. Pintus, E. Giannoni, T. Schrader, M. Puhr, P. Chiarugi, M. L. Taddei, Oncotarget 2016, 7, 61890-61904.

146. Protein Camouflage: Supramolecular Anion Recognition by Ubiquitin. M. Mallon, S. Dutt, T. Schrader, P. B. Crowley, ChemBioChem 2016, 17, 774-483.

145. Characterizing the Effect of Multivalent Conjugates of Aβ-specific Ligands and Metal Nanoparticles on Neurotoxic Fibrillar Aggregation. C. Streich, L. Akkari, C. Decker, J. Bormann, C. Rehbock, A. Müller-Schiffmann, F. C. Niemeyer, L. Nagel-Steger, D. Willbold, B. Sacca, C. Korth, T. Schrader, S. Barcikowski, ACS Nano 2016, 10, 7582-7597.

144. Reducing synuclein accumulation improves neuronal survival after spinal cord injury. S. M. Fogerson, A. J. van Brummen, D. J. Busch, S. R. Allen, R. Roychaudhuri, S. M. L. Banks, F.-G. Klärner, T. Schrader, G. Bitan, and J. R. Morgan, Exp. Neurol. 2016, 278, 105-115.

Publikationen   2015

143. Passende Kleider für Proteine schneidern. T. Schrader, C. Heid, B. Wettig, Nachrichten aus der Chemie 2015, 63, 1068-1072.

142. Toxicity Inhibitors protect Lipid Membranes from Disruption by Aß42. R. Malishev, S. Nandi, S. Kolusheva, Y. Levi-Kalisman, F.-G. Klärner, T. Schrader, G. Bitan, R. Jelinek, ACS Chem. Neurosci. 2015, 6, 1860-1869. 

141. The Lys-specific molecular tweezer, CLR01, inhibits the late stages of p53 DNA binding domain aggregation and toxicity.  G. Herzog, L. Engel, M. D. Shmueli, E. Gazit, F.-G. Klärner, T. Schrader, G. Bitan, and D. Segal, Biochemistry 201554, 3729–3738.

140. A molecular tweezer antagonizes seminal amyloid and HIV infection. E. Lump, L. M. Castellano, C. Meier, J. Seeliger, N. Erwin, C. M. Stürzel, S. Usmani, R. M. Hammond, J. von Einem, G. Gerold, F. Kreppel, K. Bravo-Rodriguez, T. Pietschmann, V. M. Holmes, D. Weissman, F. Kirchhoff, T. Weil, T. Schrader, G. Bitan, E. Sanchez-Garcia, R. Winter, J. Shorter*, and J. Münch*, eLife 2015, 4, e05397.

139. Hybridization of an Aβ-specific antibody fragment with aminopyrazole-based β-sheet ligands displays striking enhancement of target affinity. M. Hellmert, A. Müller-Schiffmann, M. S. Peters, C. Korth,* T. Schrader*, Org. Biomol. Chem. 2015, 13, 2974-2979.138. Molecular tweezers inhibit islet amyloid polypeptide assembly and toxicity by a new mechanism. D. H. J. Lopes, A. Attar, G. Nair, E. Y. Hayden, Z. Du, K. McDaniel, S. Dutt, H. Bandmann, K. Bravo-Rodriguez, S. Mittal, F.-G. Klärner, C. Wang, E. Sanchez-Garcia, T. Schrader, G. Bitan, ACS Chem. Biol. 2015, 10, 1555-1569

138. Molecular tweezers inhibit islet amyloid polypeptide assembly and toxicity by a new mechanism. D. H. J. Lopes, A. Attar, G. Nair, E. Y. Hayden, Z. Du, K. McDaniel, S. Dutt, H. Bandmann, K. Bravo-Rodriguez, S. Mittal, F.-G. Klärner, C. Wang, E. Sanchez-Garcia, T. Schrader, G. Bitan, ACS Chem. Biol. 2015, 10, 1555-1569

137. Amyloid β-protein Assembly: The Effect of Molecular Tweezer CLR01 and CLR03. X. Zheng, D.-Y. Liu, F.-G. Klärner, T. Schrader, G. Bitan, and M.T. Bowers, J. Phys. Chem. B, 2015119, 4831-4841

Publikationen   2014

136. Safety and pharmacological characterization of the molecular tweezer CLR01 – a broad-spectrum inhibitor of amyloid proteins’ toxicity. A. Attar, W.-T. Coco Chan, F.-G. Klärner, T. Schrader, G. Bitan, BMC Pharmacology and Toxicology 2014, 15:23.

135. Affinity Polymers Tailored for the Protein A Binding Site of Immunoglobulin G Proteins. Latza, P., Gilles, P., Schaller, T. and Schrader, T., Chem. Eur. J. 2014, 11479-11487. DOI: 10.1002/chem.201402399.

134. Molecular Basis for Preventing α-Synuclein Aggregation by a Molecular Tweezer. S. Acharya, B. M. Safaie, P. Wongkongkathep, M. I. Ivanova, A. Attar, F.-G. Klärner, T. Schrader, J. A. Loo, G. Bitan, L. J. Lapidus, J. Biol. Chem. 2014, 289, 10727-10737. (DOI: 10.1074/jbc.M113.524520)

133. Molecular Tweezers Targeting Transthyretin Amyloidosis. Nelson Ferreira, Alda Pereira-Henriques, Aida Attar, Frank-Gerrit Klärner, Thomas Schrader, Gal Bitan, Maria João Saraiva, Maria Rosário Almeida*, Neurotherapeutics 2014, 11, 450-461. (DOI 10.1007/s13311-013-0256-8)

Publikationen   2013

132. Linker effects on Amino Acid and Peptide Recognition by Molecular Tweezers. C. Som Dutt, Constanze Wilch, Thomas Gersthagen, Christoph Wölper, Andrea Anna Sowislok, Frank-Gerrit Klärner,* Thomas Schrader,* Eur. J. Org. Chem. 2013, 7705–7714.

131. Molecular Tweezers with Varying Anions: A Comparative Study. S. Dutt, C. Wilch, T. Gersthagen, P. Talbiersky, K. Bravo-Rodriguez, M. Hanni, E. Sánchez-García, C. Ochsenfeld*, F.-G. Klärner*, T. Schrader*, J. Org. Chem. 2013, 78, 6721–6734.

130. Unraveling the function of paralogs of the aldehyde dehydrogenase super family from Sulfolobus solfataricus. Esser, D., Kouril, T., Talfournier, F., Polkowska, J., Schrader, T., Bräsen, C., Siebers, B., Extremophiles 2013, 17, 205-216.

129. Transport of supramolecular drugs across the cell membrane by calcium phosphate nanoparticles. O. Rotan, V. Sokolova, P. Gilles, W. Hu, S. Dutt, T. Schrader, and M. Epple, accepted by Mater. Sci. Eng. Technol. 2013, 44, 176-182.

128. Molecular tweezers modulate 14-3-3 protein-protein interactions. David Bier, Rolf Rose, Kenny Bravo-Rodriguez, Maria Bartel, Juan Manuel Ramirez-Anguita, Som Dutt, Constanze Wilch, Frank Klärner, Elsa Sanchez-Garcia*, Thomas Schrader*, Christian Ottmann*, Nat. Chem. 2013, 5, 234-239.

127. Aromatic Interactions by Molecular Tweezers and Clips in Chemical and Biological Systems. F.-G. Klärner, T. Schrader, Special Issue “Aromatic Interactions in Chemistry and Biology”, Acc. Chem. Res. 2013, 46, 967–978.

126. Ditopic Arginine-Aspartate Binders recognize RGD loops. T. Gersthagen, J. Hofmann, F.-G. Klärner, C. Schmuck, T. Schrader, Eur. J. Org. Chem. 2013, 1080-1092.

Publikationen   2012

125. Discovery and Structure Activity Relationship of Small Molecule Inhibitors of Toxic β-Amyloid-42 Fibril Formation. Heiko Kroth, Annalisa Ansaloni, Yvan Varisco, Asad Jan, Nampally Sreenivasachary, Valérie Giriens, Sophie Lohman, María Pilar López-Deber, Oskar Adolfsson, Maria Pihlgren, Paolo Paganetti, Wolfgang Froestl, Luitgard Nagel-Steger, Dieter Willbold, Thomas Schrader, Andrea Pfeifer, Hilal A. Lashuel, and Andreas Muhs, J. Biol. Chem. 2012, 287, 34786-34800.

124. Protection of primary neurons and mouse brain from Alzheimer’s pathology by molecular tweezers. Aida Attar; Cristian Ripoli; Panchanan Maiti; Sharmistha Sinha; Tingyu Liu; Mychica R. Jones; Fusheng Yang; Greg D. Gale; Kristin Lichti-Kaiser; Chi-hong Tseng; Miao Tan; Cui-Wei Xie; Jeffrey L. Straudinger; Frank-Gerrit Klärner; Thomas Schrader; Sally A. Frautschy; Claudio Grassi; Gal Bitan*. Brain 2012, 135, 3735-3748.

123. Protein Recognition: Calixarene Connection. T. Schrader, Nat. Chem. 2012, 4, 519-520.

122. Artificial Signal Transduction with a Primary and Secondary Messengers. Kai Bernitzki, Michael Maue, Thomas Schrader, Chem. Eur. J. 2012, 18, 13412-13417.

121. Comparison of three amyloid assembly inhibitors – the sugar scyllo-inositol, the polyphenol epigallocatechin gallate, and the molecular tweezer CLR01. Sinha, S., Du, Z., Maiti, P., Klärner, F.-G., Schrader, T., Wang, C., Bitan, G.,* Chem. Neurosci. 2012, 3, 451−458.

120. A Novel “Molecular Tweezer” Inhibitor of α-Synuclein Neurotoxicity in vitro and in vivo. S. Prabhudesai, S. Sinha, A. Kotagiri, A. Fitzmaurice, F.-G. Klärner, T. Schrader, G. Bitan,* J. M. Bronstein,* Neurotherapeutics 2012, 9, 464-476.

119. Dimeric Calixarenes – A New Family of Major Groove Binders. Wenbin Hu, Caroline Blecking, Marijeta Kralj, Lidija Šuman, Ivo Piantanida, Thomas Schrader, Chem. Eur. J. 2012, 18, 3589-3597.

118. Interactions of Calix[n]arenes with Nucleic Acids. M. S. Peters, M. Li and T. Schrader*, Nat. Prod. Commun. 2012, 7, 409-417.

Publikationen   2011

117. Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins. Sharmistha Sinha, Dahabada H. J. Lopes, Zhenming Du, Eric S. Pang, Akila Shanmugam, Aleksey Lomakin, Peter Talbiersky, Annette Tennstaedt, Kirsten McDaniel, Reena Bakshi, Pei-Yi Kuo, Michael Ehrmann, George B. Benedek, Joseph A. Loo, Frank-Gerrit Klärner, Thomas Schrader, Chunyu Wang, Gal Bitan*, J. Am. Chem. Soc. 2011, 133, 16958-16969.

116. Noncovalent Inclusion of Nucleosides and Nucleotides in Water-Soluble Molecular Clips, Frank Bastkowski, Jolanta Polkowska, Thomas Schrader*, Frank-Gerrit Klärner*, Commemorative Issue for A. Eschenmoser, Heterocycles 2011, 82, 1549-1567.

115. A Modular Synthetic Route to Dimeric Calixarenes: A New Family of DNA Major Groove Binders. Caroline J. Breitkreuz, Wenbin Hu, Reza Zadmard, Antara Dasgupta, Thomas Schrader, Synthesis 2011, 1193-1204.

114. Artificial synthetic receptors as regulators of protein activity. S. Dutt, C. Wilch, T. Schrader, Invited Feature-Article, Chem. Commun. 2011, 47, 5376–5383.

113. Rational Design of β-Sheet Ligands against Aβ42-induced toxicity. Katrin Hochdörffer, Julia März-Berberich, Luitgard Nagel-Steger, Matthias Epple, Wolfgang Meyer-Zaika, Anselm H.C. Horn, Heinrich Sticht, Sharmistha Sinha, Gal Bitan, Thomas Schrader*, J. Am. Chem. Soc. 2011, 133, 4348-4358.

Publikationen   2010

112. Artificial RGD Receptor Molecules, Thomas Gersthagen, Carsten Schmuck, Thomas Schrader*, Supramol. Chem. 2010, 22, 853-861 (Special Commemorative Issue for Dmitry Rudkevich).

111. Maßgeschneiderte Nanomaterialien zur Beeinflussung biologischer Funktionen, Thomas Schrader, Unikate 2010, 18, 22-31.

110. Internationale Patentanmeldung: New Compounds for the Treatment of Diseases Related to Protein Misfolding. Inventors: T. Schrader, K. Hochdörffer, J. März-Berberich, G. Bitan, S. Sinha. Filed October 5, 2010. Amtliches Kennzeichen: PCT/EP 2010/000437.

109. Gesteigerte Wirksamkeit durch Synergismus: Verknüpfung unabhängiger Wirkstoffklassen zu Hybridsubstanzen. Andreas Müller-Schiffmann, Julia März, Aksana Andrjevna, Raik Rönicke, Dirk Bartnik, Olexandr Brener, Janine Muyrers, Anselm Horn, Kurt Gottmann, Klaus Reymann, S. Aileen Funke, Luitgart Nagel-Steger, Christine Moriscot, Guy Schoehn, Heinrich Sticht, Dieter Willbold, Thomas Schrader, Carsten Korth; Angew. Chem. Int. Ed. 2010, 122, 8925–8928.

108. Development and evaluation of a fluorescence microplate assay for quantification of heparins and other sulfated carbohydrates, S. Lühn, Sun Wei, T. Schrader, S. Alban. J. Pharm. Biomed. Anal. 2010, 52, 1-8.

107. RAFT polymers for Protein Recognition. Alan Tominey, Julia Liese, Sun Wei, Klaus Kowski, T. Schrader, Arno Kraft*, Beilstein J. Org. Chem. 2010, 6, No. 66.

106. The Effect of Molecular Clips and Tweezers on Enzymatic Reactions by Binding Coenzymes and Basic Amino acids. Frank-Gerrit Klärner, Thomas Schrader, Jolanta Polkowska, Frank Bastkowski, Peter Talbiersky, Mireia Campaña Kuchenbrandt, Torsten Schaller, Herbert de Groot, Michael Kirsch, Pure & Applied Chemistry 2010, 82, 991-999.

Publikationen   2009

105. Entirely Artificial Signal Transduction With a Primary Messenger. K. Bernitzki, M. Maue, T. Schrader, Angew. Chem. 2009, 48, 8001-8005. 

104. Calixarene Dimers for Diphosphate Recognition. Reza Zadmard,* Saeed Taghvaei-Ganjali, Banafsheh Gorji, Thomas Schrader,* in revision for Chem. Asian. J. 2009

103. U.S. Provisional Patent Application UCLAP047P: Molecular Tweezers for the treatment of amyloid-related diseases; Inventors: Gal Bitan,* Akila Shanmugam, Aleksey Lomakin, Thomas Schrader,* Frank-Gerrit Klärner,* Peter Talbiersky, Jolanta Polkowska, Frank Bastkowski, Sharmistha Sinha, Sally Frautschy. Filed March 5, 2009.

102. Modulation of aggregate size- and shape-distributions of the amyloid-β peptide by a designed β-sheet breaker. Luitgard Nagel-Steger,* Borries Demeler, Wolfgang Meyer-Zaika, Katrin Hochdörffer, Thomas Schrader, Dieter Willbold, accepted by Eur. Biophys. J. 2009 (special issue for the AUC-HYDRO-2008 meeting).

101. Multivalent Synthetic Receptors for Biomacromolecules. Contribution to “Cellular and Biomolecular Recognition by Synthetic and non-Biological Molecules”, R. Jelinek (ed), Wiley-VCH, Weinheim. July 2009.

100. A Mechanism of Efficient G6PD Inhibition by a Molecular Clip. M. Kirsch, P. Talbiersky, J. Polkowska, F. Bastkowski,  T. Schaller, H. de Groot, F. Klärner, T. Schrader, Angew. Chem. 2009, 48, 2886-2890.

99. Interactions of Small Protected Peptides with Aminopyrazole Derivatives: The Efficiency of capping a β-Sheet Model in the Gas Phase. H. Fricke, A. Gerlach, C. Unterberg, M. Wehner, T. Schrader, M. Gerhards*, Angew. Chem. 2009, 48, 900-904.

98. A combined experimental and theoretical study of the pH-dependent binding mode of NAD+ by water-soluble molecular clips. J. Polkowska, F. Bastkowski, T. Schrader*, F.-G. Klärner*, J. Zienau. F. Koziol, C. Ochsenfeld,* J. Phys. Org. Chem. online 2009, DOI 10.1002/poc.1519.

97. Protein adsorbers from surface-grafted copolymers with specific binding sites. Dongming He, Wei Sun, T. Schrader, M. Ulbricht, J. Mater. Chem. 2009, 19, 253-260.

96. Fluorescent water-soluble molecular clips. Self-association and formation of adducts in aqueous and methanol solution. B. Branchi, P. Ceroni, V´. Balzani, M. Casas Cartagena, T. Schrader, F.-G. Klärner, F. Vögtle. New J. Chem. 2009, 33, 397-407.

Publikationen   2008

95. Nagel-Steger L, Demeler B, Hochdörfer K, Schrader T Willbold D Modulation of aggregate size and shape distributions of amyloid-β peptide solutions by a designed β-sheet breaker. NIC Workshop 2007, From Computational Biophysics to System Biology CBSB08. Eds. Ulrich. E. Hansmann, Jan H. Meinke, Sandipan Mohanty, Walter Nadler, Olav Zimmermann. NIC Series Volume 40, 333-336 (2008).

94. Lipid/Polydiacetylene Films for Colorimetric Protein Surface-Charge Analysis. S. Friedman, S. Kolusheva, R. Volinsky, L. Zeiri, T. Schrader*, R. Jelinek*, Anal. Chem. 2008, 80, 7804-7811.

93. Biamphiphilic Bifunctional Transmembrane Building Blocks for Artificial Signal Transduction. K. Bernitzki, M. Maue, M. Ellermann, T. Schrader, Synthesis 2008 (special issue dedicated to RWH).

92. Molecular Clip and Tweezer introduce new Mechanisms of Enzyme Inhibition. Peter Talbiersky, Frank Bastkowski, Frank-Gerrit Klärner, Thomas Schrader*,  J. Am Chem. Soc. 2008, 130, 9824-9828

91. Investigation of secondary structure elements by IR/UV double resonance spectroscopy: Analysis of an isolated β-sheet model system. H. Fricke, A. Funk, T. Schrader, M. Gerhards,* J. Am Chem. Soc. 2008, 130, 4692-4698

90. DNA Recognition with Large Calixarene Dimers and Varying Spacers. Caroline Breitkreuz, Reza Zadmard, T. Schrader*, Supramolecular Chemistry 2008, 20, 109-115.

89. Hierarchical Self-Assembly of Nanorosettes in Water. P. Rzepecki, K. Hochdoerffer, T. Schaller, J. Zienau, K. Harms, C. Ochsenfeld, X. Xie X, T. Schrader, J. Am. Chem. Soc. 2008, 130, 586-591.

Publikationen   2007

88. Secondary structure binding motifs of the jet cooled tetrapeptide model Ac-Leu-Val-Tyr(Me)-NHMe. H. Fricke, G. Schäfer, T. Schrader, M. Gerhards*, submitted to Phys. Chem. Chem. Phys. 2007.

87. A Noncovalent Switch for Lysozyme. Kirstin Wenck, Thomas Schrader,  J. Am. Chem. Soc. 2007, 129, 16015-16019. 

86. A Polymeric Fluorescence Sensor for Heparin. Wei Sun, Heinz Bandmann, Thomas Schrader*, Chem. Eur. J. 2007, 13, 7701-7707.

85. Creative Chemical Sensor Systems. in: Topics of Current Chemistry 277. T. Schrader, Editor, Springer Verlag, Heidelberg, 2007.

84. Artificial Ditopic RGD Receptors. C. Schmuck*, Daniel Rupprecht, Matthias Junkers, T. Schrader*, Chem. Eur. J. 2007, 13, 6864-6873.

83. Artificial Protein Sensors. T. Schrader*, S. Koch, Mol. BioSyst. 2007, 3, 241-248.

82. Synthesis and Binding studies of Alzheimer-Ligands on Solid Support. Petra Rzepecki, Nina Geib, Manuel Peifer, Frank Biesemeier, Thomas Schrader*, J. Org. Chem. 2007, 72, 3614 -3624.

Publikationen   2006

81. Color sensing of proteins by calixarene receptors embedded in lipid/polydiacetylene vesicles. Sofiya Kolusheva, Reza Zadmard, Thomas Schrader*, Raz Jelinek*, J. Am. Chem. Soc. 2006, 128, 13592-13598.

80. Entirely Artifical Signal Transduction with Adrenaline. Michael Maue, Manuel Ellermann, Thomas Schrader*, invited contribution to J. Rec. Signal Trans. 2006, 26, 473-485 (Special Issue: Proceedings of the 10th Swiss Receptor Workshop).

79. Dendrimeric Bisphosphonates for Multivalent Protein Surface Binding. Markus Arendt, Wei Sun, Jens Thomann, Xiulan Xie, Thomas Schrader*, Chem. Asian J. 2006, 1, 544-554.

78. Nucleoside Sensing. Michael Fokkens, Thomas Schrader*, Frank-Gerrit Klärner*, invited contribution to Sensors 2006, 6, 860-873 (Special Issue: Supramolecular Sensors).

77. Tuning Linear Copolymers into Protein-Specific Hosts. S. Koch, C. Renner, T. Schrader*, Angewandte Chemie Int. Ed. 2006, 45, 6352-55.

76. Heterozyklische Verbindungen mit Wirkung gegen neurodegenerative Erkrankungen. Patentanmeldung vom 28.03.2006. Erfinder: F. Biesemeier, K. Hochdörffer, L. Nagel-Steger, D. Riesner, T. Schrader. DE 10 2006 015 140.2.

75. Amino Acid, Peptide and Protein Sensing with Calixarenes. R. Zadmard* , T. Schrader, in: Calixarenes in the Nanoworld, eds. J. Harrowfield and J. Vicens, Springer-Verlag, Berlin, 2006.

74. Molecular Tweezer and Clip in Aqueous Solution: Unexpected Self-Assembly, Powerful Host-Guest Complex Formation, Quantum Chemical 1H-NMR Shift Calculation.. Frank-Gerrit Klärner*, Björn Kahlert, Anke Nellesen, Jan Zienau, Christian Ochsenfeld*, Thomas Schrader*, J. Am. Chem. Soc. 2006, 128, 4831-4841.

73. DNA Recognition by Large Calixarene Dimers. R. Zadmard, T. Schrader*, Angew. Chem. Int. Ed. 2006, 45, 2703-2706.

72. Arginine- and Lysine-Specific Polymers for Protein Recognition and Immobilization. C. Renner, J. Piehler, T. Schrader*, J. Am. Chem. Soc. 2006, 128, 620-628.

71. Sequence-Selective Peptide Recognition with Designed Modules. M. Wehner, D. Janssen, G. Schäfer, T. Schrader*, Eur. J. Org. Chem. 2006, 138-153.

Publikationen   2005

70. Inclusion of Thiamine Diphosphate and S-Adenosylmethionine at their Chemically Active Sites. Thomas Schrader*, Michael Fokkens, Frank-Gerrit Klärner*, Jolanta Polkowska, Frank Bastkowski, J. Org. Chem. 2005, 70, 10227-10237.

69. A Molecular Tweezer for Lysine and Arginine. Michael Fokkens, Thomas Schrader*, Frank-Gerrit Klärner*, J. Am. Chem. Soc. 2005, 127, 14415-14421.

68. Selective detection of catecholamines by synthetic receptors embedded in chromatic polydiacetylene vesicles. Sofiya Kolusheva, Oliver Molt, Michael Herm, Thomas Schrader*, Raz Jelinek*, J. Am. Chem. Soc. 2005, 127, 10000-10001.

67. Functional Synthetic Receptors, Eds. Thomas Schrader, Andrew Hamilton, Wiley-VCH, Weinheim, 2005, ISBN 3527306552.

66. Arginin- und Lysin-spezifische Polymere für die Proteinerkennung und Immobilisierung. Patentanmeldung vom 9.12.2004. Erfinder: T. Schrader, C. Renner, M. Arendt, S. Koch. DE 10 2005 059 379.8.

65. A Color Sensor for Catecholamines. M. Maue, T. Schrader*, Angew. Chem. 2005, 117, 2305-2310, Angew. Chem. Int. Ed. 2005, 44, 2265-2270.

64. β-Sheet Ligands in Action - KLVFF-Recognition by Aminopyrazole Hybrid Receptors in Water. P. Rzepecki, T. Schrader*, J. Am. Chem. Soc. 2005, 127, 3016-3025.

63. Nanomolar Protein Sensing with Embedded Receptor Molecules. R. Zadmard, T. Schrader*, J. Am. Chem. Soc. 2005, 127, 904-915.

62. Selective Complexation of N-Alkylpyridinium Salts: Binding of NAD+ in Water. Michael Fokkens, Christian Jasper, Thomas Schrader*, Felix Koziol, Christian Ochsenfeld, Jolanta Polkowska, Matthias Lobert, Björn Kahlert, Frank-Gerrit Klärner*, Chem. Eur. J. 2005, 11, 477-494.

Publikationen   2004

61. Neue Wirkstoffe zu Therapie, Diagnostik und Prophylaxe der Makuladegeneration. Patentanmeldung vom 24.11.2004. Erfinder: T. Schrader, M. Fokkens, R. Zadmard, C. Jasper, F. Klärner, J. Polkowska, F. Bastkowski. DE 10 2004 056 822.7.

60. Structure of the tripeptide model Ac-Leu-Val-Tyr(Me)NHMe and its cluster with water investigated by IR/UV double resonance spectroscopy. H. Fricke, A. Gerlach, C. Unterberg, P. Rzepecki, T. Schrader, M. Gerhards*, Phys. Chem. Chem. Phys. 2004, 6, 4636-4641.

59. Prevention of Alzheimer’s associated Aß aggregation by rationally designed nonpeptidic β-sheet ligands. P. Rzepecki, L. Nagel-Steger, S. Feuerstein, U. Linne, O. Molt, R. Zadmard, K. Aschermann, M. Wehner, T. Schrader*, D. Riesner*, J. Biol. Chem. 2004, 279, 47479-47505.

58. On the Role of Phosphoramidite Ligands in the Conjugate Addition of Diorganozincs to Enones. T. Pfretzschner, L. Kleemann, B. Janza, K. Harms, T. Schrader*, Chem. Eur. J. 2004, 10, 6048-6057.

57. New heterocyclic β-sheet ligands with peptidic recognition elements. P. Rzepecki, H. Gallmeier, N. Geib, Katarina Cernovska, B. König*, T. Schrader*, J. Org. Chem. 2004, 69, 5168-5178.

56. PEG-supported Synthesis of Pyrazole Oligoamides with Peptide β-Sheet Affinity. Katerina Cernovská, Miriam Kemter, Hans-Christoph Gallmeier, Petra Rzepecki, Thomas Schrader* and Burkhard König*, Org. Biomol. Chem. 2004, 2, 1603-1611.

55. Adrenaline Recognition in Water. O. Molt, D. Rübeling, G. Schäfer, T. Schrader*, Chem. Eur. J. 2004, 10, 4225-4232.

54. Relative Binding Affinities of Molecular Capsules investigated by ESI-MS. R. Zadmard, T. Schrader*, U. Linne*, Chem. Eur. J. 2004, 10, 4233-4239.

53. Multipoint Recognition of Basic Proteins at a Membrane Model. R. Zadmard, M. Arendt, T. Schrader*, J. Am. Chem. Soc. 2004, 126, 7752 - 7753.

52. Artificial Receptors for the Stabilization of ß-Sheet Structures. T. Schrader,* M. Wehner, P. Rzepecki, Beitrag zum Buch "Bioorganic Chemistry Highlights II: From Chemistry to Biology", C. Schmuck, H. Wennemers, Eds., Wiley-VCH, Weinheim/ New York, 2004, ISBN 3527306560.

Publikationen   2003

51. Aminopyrazole Oligomers for β-Sheet Stabilization of Peptides. P. Rzepecki, M. Wehner, O. Molt, R. Zadmard, T. Schrader,* Synthesis 2003, 1815-1826.

50. Highly Selective Recognition of Adrenergic Receptor Substrates at the Air / Water Interface. O. Molt, T. Schrader,* Angew. Chem. 2003, 115, 5667-5671. Angew. Chem. Int. Ed. 2003, 42, 5509-5513.

49. Capsule-like Assemblies in Polar Solvents. R. Zadmard, M. Junkers, T. Schrader,* T. Grawe, A. Kraft*, J. Org. Chem. 2003, 68, 6511-6521.

48. A Selective Biomimetic Tweezer for Noradrenaline. O. Molt, D. Rübeling, T. Schrader,* J. Am. Chem. Soc. 2003, 125, 12086-12087.

47. Structure of the protected dipeptide Ac-Val-Phe-OMe in the gas phase: Towards a β-sheet model system. C. Unterberg, A. Gerlach, T. Schrader, M. Gerhards,* J. Chem. Phys. 2003, 118, 8296-8300.

46. Molecular Recognition of Amidines in Water, T. Schrader*, T. Grawe, G. Schäfer, Org. Lett. 2003, 5, 1641-1644.

Publikationen   2002

45. Asymmetric Synthesis with Chiral Cyclic Phosphorus Auxiliares, O. Molt, T. Schrader*, Synthesis 2002, 2633-2670.

44. Conformationally rigid hosts containing phosphonic units., P. Finocchiaro,* S. Failla , G. A. Consiglio, M. Wehner, T. Grawe, T. Schrader*, Phoshorus, Sulfur,and Silicon 2002, 177, 1633-1636.

43. Clusters of a Protected Amino Acid with Pyrazole Derivatives: ß-Sheet Model Systems in the Gas Phase., C. Unterberg, A. Gerlach, T. Schrader*, M. Gerhards*, Eur. Phys. J. D 2002, 20, 543-550.

42. Heterocyclische Wirkstoffe auf Aminopyrazolbasis., Erfinder: T. Schrader*, D. Riesner*, L. Nagel-Steger, K. Aschermann, C. Kirsten, P. Rzepecki, O. Molt, R. Zadmard, M. Wehner, Patentschrift DE 102 21 052.7 vom 10.05.2002 (Anmeldung).

41. The First Synthetic Receptor for the RGD-Sequence, S. Rensing, T. Schrader*, Org. Lett. 2002, 4, 2161-2164.

40. Self-Assembly of Ball-Shaped Molecular Complexes in Water, T. Grawe, T. Schrader*, A. Kraft*, J. Org. Chem. 2002, 67, 3755-3763.  

39. Self-Assembly of Molecular Capsules in Polar Solvents, R. Zadmard, T. Schrader*, T. Grawe, Arno Kraft*, Org. Lett. 2002, 4, 1687-1690.

38. Modular Building Blocks for Amino Acid Recognition in Peptides, T. Schrader*, M. Wehner, Angew. Chem. 2002, 114, 1827-1831, Angew. Chem. Int. Ed. 2002, 41, 1751-1754.

37. Selective Complexation of N-Alkylpyridinium Salts: Recognition of NAD+ in Water, C. Jasper, T. Schrader*, J. Panitzky, F.-G. Klärner*, Angew. Chem. 2002, 114, 1411-1414, Angew. Chem. Int. Ed. 2002, 41, 1355-1358.

36. Towards Synthetic Adrenaline Receptors - Shape-Selective Adrenaline Recognition in Water, M. Herm, O. Molt, T. Schrader*, Chem. Eur. J. 2002, 8, 1485-1499.

Publikationen   2001

35. Optimization of a Synthetic Arginine Receptor - Systematic Tuning of Noncovalent Interactions, S. Rensing, M. Arendt, A. Springer, T. Grawe, and T. Schrader*, J. Org. Chem. 2001, 66, 5814-5821.

34. Towards Synthetic Adrenaline Receptors, Part IV (Modular Synthesis of a New Family of Macrocyclic Hosts Designed for Biomimetic Adrenaline Binding). M. Herm, O. Molt, T. Schrader*, Angew. Chem 2001, 113, 3244-3248, Angew. Chem. Int. Ed. 2001, 40, 3148-3151.

33. Towards Synthetic Adrenaline Receptors, Thomas Schrader*, Michael Herm, Proceedings of the 2nd International Conference on Supramolecular Science and Technology (ICSST-2), Special Issue of Materials Science and Engineering C 2001, 18, 147-155.

32. A New Receptor Molecule for Lysine and Histidine in Water Strong Binding of Basic Amino Acid Esters by a Macrocyclic Host, Thomas Grawe, Thomas Schrader*, Paolo Finocchiaro*, Giuseppe Consiglio,  Salvatore Faillad, Org. Lett. 2001, 3, 1597-1600.

Publikationen   2000

31. Molecular Receptors for Amidinium Cations - Strong and Selective Binding of Mono- and Bisamidinium Salts by m-Xylylene Bisphosphonate Moieties, T. Schrader*, T. Grawe, ECSOC4, 2000, C 27. The 4th International Electronic Conference on Synthetic Organic Chemistry; www.unibas.ch/mdpi/ecsoc-4/section_c.htm (ISBN 3-906980-05-7).

30. A New Receptor Molecule for Lysine and Histidine in Water - Strong Binding of Basic Amino Acids by a Macrocyclic Host. T. Schrader *, T. Grawe, P. Finocchiaro, Salvatore Failla and Giuseppe Consiglio, ECSOC4, 2000, C 26. The 4th International Electronic Conference on Synthetic Organic Chemistry; www.unibas.ch/mdpi/ecsoc-4/section_c.htm (ISBN 3-906980-05-7).

29. Trendberichte Organische Chemie 1999: Molekulare Erkennung, T. Schrader, S. Kubik, Nachr. Chem. 2000, 48, 276-280. 28. A Chiral Sensor for Arginine and Lysine, T. Schrader*, M. Wehner, P. Finocchiaro, S. Failla, G. Consiglio, Org. Lett. 2000, 2, 605-608.

28. A Chiral Sensor for Arginine and Lysine. M. Wehner, S. Failla, G. Consiglio, P. Finocchiaro, T. Schrader*, Org. Lett. 2000, 2, 605-608.

27. Self-organized Ball-Shaped Molecular Assemblies in Water, Thomas Grawe, Thomas Schrader*, Marion Gurrath* , Arno Kraft*, Frank Osterod, J. Phys. Org. Chem. 2000, 13, 670-673.

26. Self-organization of Spheroidal Molecular Assemblies in Polar Solvents. Thomas Grawe, Thomas Schrader*, Marion Gurrath* , Arno Kraft*, Frank Osterod, Org. Lett. 2000, 2, 29-32.

25. Towards Synthetic Adrenaline Receptors, Part III (Molecular Recognition of Agonists and Antagonists of the β-Adrenaline Receptor in polar solvents with a Macrocyclic Bisphosphonate Receptor Molecule). T. Schrader*, M. Herm, Chem. Eur. J. 2000, 6, 47-53.

Publikationen   1999

24. Synthetic Adrenaline Receptors based on Bisphosphonates. T. Schrader, M. Herm*, Phoshorus, Sulfur,and Silicon 1999, 144-146, 749.

23. Chelate Complexes with the P=O-Double Bond - A New Concept For Asymmetric Synthesis. T. Schrader*, C. Kirsten, M. Herm, Phoshorus, Sulfur,and Silicon 1999, 144-146, 161.

22. Chelate Complexes with the P=O-Double Bond - a New Concept for Molecular Recognition. Einladung zu einem Review-Artikel über eigene Arbeiten für J. Inclusion Phenom. Macrocycl. Chem. 1999, 34, 117-131.

21. 1. Synthetic Adrenaline Receptors; 2. Synthetic Peptide Receptors. T. Schrader*, C. Kirsten, M. Herm, Beitrag zum Buch "Bioorganic Chemistry", U. Diederichsen, Th. K. Lindhorst, B. Westermann, L. A. Wessjohann, Eds., Wiley-VCH, Weinheim/New York, 1999, ISBN 3-527-29665-4, p. 215.

Publikationen   1998

20. Anomerselective Molecular Recognition of Free Amino Sugars with Simple Biomimetic Bisphosphonate Receptor Molecules, T. Schrader, J. Am. Chem. Soc. 1998, 120, 11816-11817.

19. Unexpected Enhancement of Enantioselectivity in Copper (II) Catalyzed Conjugate Addition of Diethylzinc to Cyclic Enones with Novel TADDOL phosphorus amidite ligands, E. Keller, J. Maurer, R. Naasz, T. Schrader, A. Meetsma, B. Feringa*, Tetrahedron Asymm. 1998, 9, 2409-2413.

18. Chelatkomplexe mit der P=O-Doppelbindung - ein neues Konzept für die asymmetrische Synthese und für die molekulare Erkennung, Habilitationsschrift, Düsseldorf, 1998.

17. Strong Binding of Arylguanidinium Ions by Benzylic Bisphosphonates - Evidence for π-cation and π,π-interactions, T. Schrader, Tetrahedron Lett. 1998, 39, 517-520.

16. Toward Synthetic Adrenaline Receptors: Strong, Selective and Biomimetic Recognition of Biologically Active Amino Alcohols by Bisphosphonate Receptor Molecules, T. Schrader, J. Org. Chem 1998, 63, 264-272.

Publikationen   1997

15. Intermolecular β-Sheet Stabilisation with Aminopyrazoles, T. Schrader*, C. N. Kirsten, J. Am. Chem. Soc. 1997, 119, 12061-12068.

14. Molecular Imprinting for the Preparation of Enzyme-Analogous Polymers, G. Wulff*, T. Groß, R. Schönfeld, T. Schrader, C. Kirsten, ACS Symposium Series Volume on Recognition with Imprinted Polymers, 213th National Meeting of the American Chemical Society 13.-17. April 1997, San Francisco.

13. Strong Binding of Alkyl Guanidinium Ions by Molecular Tweezers - an Artificial Selective Arginine Receptor Molecule with a Biomimetic Recognition Pattern, T. Schrader, Chem. Eur. J. 1997, 3, 1537-1541.

12. A General Strategy to Enantiomerically Pure Aliphatic and Olefinic Ketone Cyanohydrins by Stereoselective Alkylation of Umpoled Aldehyde Derivatives, C. N. Kirsten, M. Herm, T. H. Schrader*, J. Org. Chem. 1997, 62, 6882-6887.

11. Stereoselective Umpolung Reactions with metallated P-chiral Cyanohydrin Phosphates - enantioselective Synthesis of tertiary Cyanohydrins, T. Schrader, Chem. Eur. J. 1997, 3, 1273-1282.

Publikationen   1996

10. Auf dem Weg zu synthetischen Adrenalinrezeptoren - starke Bindung von Aminoalkoholen durch Bisphosphonate, T. Schrader, Angew. Chem. 1996, 108, 2816-2818.

9. Intermolecular stabilisation of the β-sheet-conformation in dipeptides, T. Schrader*, C. Kirsten, J. Chem. Soc., Chem. Commun. 1996, 2089.

Publikationen   1995

8. Ein chirales Cyanhydrinphosphat als umgepolte Carbonylverbindung - stereoselektive Synthese von tertiären Cyanhydrinen, T. Schrader, Angew. Chem. 1995, 107, 1001-1002.

Publikationen   1992

7. Synthesis of 10-Substituted "Open Chain" Analogues of 5,10-Dideaza-5,6,7,8-tetrahydrofolic Acid (DDATHF, Lometrexol), T. H. Schrader, L. D. Walensky, E. C. Taylor*, Tetrahedron 1992, 48, 19-32.

Publikationen   1990

6. US-Patent US/18.4.90/ US 510669 der Eli Lilly Company, Indianapolis, Indiana, in Verbindung mit der Princeton University, NJ, Abteilung Prof. Dr. E. C. Taylor, vom Januar 1990 (Anmeldung) / (Europäische Patentanmeldung # 91103482.5 am 7.4.1991): Pocedures for the preparation of DDATHF-analogs with a substituent R in the 10-position and clinical use thereof as cytotoxic agents active against human T-cell derived lymphoblastic leukemia-cells (CCRF-CEM) with IC50-values below 0.01 mg/ml. Erfinder: Th. Schrader, L. D. Walensky, E. C. Taylor, Mitarbeiter der Eli Lilly Company.

5. Phosphoranaloge von Aminosäuren IV. Synthesen ungewöhnlicher 1-Aminophosphon-säuren über Diels-Alder-Reaktionen von N-Acyliminomethylphosphonsäure-Estern, Th. Schrader, W. Steglich*, Synthesis 1990, 1153-1156.

Publikationen   1989

4. Phosphoranaloge von Aminosäuren II. Synthese von α-Amino-phosphonsäuren und α-Aminophosphinsäuren, ausgehend von den entsprechenden N-Acyliminomethylphosphonsäure-Estern, Th. Schrader, W. Steglich*, Synthesis 1989, 97-101.

Publikationen   1988

3. Offenlegungsschrift der BASF-AG, D-6700 Ludwigshafen, O.Z. 0050/40064 vom 21.7.1988 (Anmeldung): Verfahren zur Herstellung des Wachstumsregulators Bis(aminomethyl)phosphinsäure oder deren sauren oder basischen Salzen.Erfinder: Schrader, Th., Steglich, W.

Publikationen   1986

2. Offenlegungsschrift der BASF-AG, D-6700 Ludwigshafen, DE 3609972 A 1 vom 30.10.1986 (Offenlegung): Verfahren zur Darstellung von optisch aktiven α-Acylamino-γ-oxocarbonsäure- und -phosphonsäureestern. Erfinder: Kober, R., Steglich, W., Schrader, Th., Enders, D., Papadopoulos, K.

1. Synthese von 1-Aminophosphonsäurederivaten über Acylimino-phosphonsäure-Ester, Th. Schrader, W. Steglich*, Synthesis 1986, 372-375.