Publikationen
Publikationen Strukturelle und Medizinische Biochemie
Es wurden 86 Publikationen gefunden
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The Molecular Footprint of Peptides on the Surface of Ultrasmall Gold Nanoparticles (2 nm) Is Governed by Steric DemandIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 128 (2024) Nr. 17, S. 4266 - 4281Online Volltext: dx.doi.org/
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Increased Cytotoxicity of Bimetallic Ultrasmall Silver–Platinum Nanoparticles (2 nm) on Cells and Bacteria in Comparison to Silver Nanoparticles of the Same SizeIn: Materials Jg. 17 (2024) Nr. 15, 3702Online Volltext: dx.doi.org/ (Open Access)
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Functional Linkers Support Targeting of Multivalent Tweezers to Taspase1In: Chemistry - A European Journal (2024) in pressOnline Volltext: dx.doi.org/ (Open Access)
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Ultrastructure and Surface Composition of Glutathione-Terminated Ultrasmall Silver, Gold, Platinum, and Alloyed Silver-Platinum Nanoparticles (2 nm)In: Inorganic Chemistry Jg. 62 (2023) Nr. 42, S. 17470 - 17485Online Volltext: dx.doi.org/
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The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPaseIn: Nature Communications Jg. 14 (2023) Nr. 1, 3258Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Potentiating Tweezer Affinity to a Protein Interface with Sequence-Defined Macromolecules on NanoparticlesIn: Biomacromolecules Jg. 24 (2023) Nr. 8, S. 3666 - 3679Online Volltext: dx.doi.org/
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Multivalent Molecular Tweezers Disrupt the Essential NDC80 Interaction with MicrotubulesIn: Journal of the American Chemical Society: JACS Jg. 145 (2023) Nr. 28, S. 15251 - 15264Online Volltext: dx.doi.org/
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Binding Methylarginines and Methyllysines as Free Amino Acids : A Comparative Study of Multiple Host ClassesIn: ChemBioChem Jg. 23 (2022) Nr. 2, e202100502Online Volltext: dx.doi.org/ (Open Access)
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Water-Based Synthesis of Ultrasmall Nanoparticles of Platinum Group Metal Oxides (1.8 nm)In: Inorganic Chemistry Jg. 61 (2022) Nr. 12, S. 5133 - 5147Online Volltext: dx.doi.org/
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Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligandIn: RSC Advances Jg. 12 (2022) Nr. 53, S. 34176 - 34184Online Volltext: dx.doi.org/ (Open Access)
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Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular TweezersIn: Biomacromolecules Jg. 23 (2022) Nr. 11, S. 4504 - 4518Online Volltext: dx.doi.org/
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Metal-Ligand Interface and Internal Structure of Ultrasmall Silver Nanoparticles (2 nm)In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 125 (2021) Nr. 21, S. 5645 - 5659Online Volltext: dx.doi.org/
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Targeting the Surface of the Protein 14-3-3 by Ultrasmall (1.5 nm) Gold Nanoparticles Carrying the Specific Peptide CRafIn: ChemBioChem Jg. 22 (2021) Nr. 8, S. 1456 - 1463Online Volltext: dx.doi.org/ (Open Access)
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Peptide-Conjugated Ultrasmall Gold Nanoparticles (2 nm) for Selective Protein TargetingIn: ACS Applied Bio Materials Jg. 4 (2021) Nr. 1, S. 945 - 965Online Volltext: dx.doi.org/ (Open Access)
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New tools to probe the protein surface : Ultrasmall gold nanoparticles carry amino acid bindersIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 125 (2021) Nr. 1, S. 115 - 127Online Volltext: dx.doi.org/ (Open Access)
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Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications Jg. 12 (2021) Nr. 1, S. 1505Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Functional Disruption of the Cancer-Relevant Interaction between Survivin and Histone H3 with a Guanidiniocarbonyl Pyrrole LigandIn: Angewandte Chemie International Edition Jg. 59 (2020) Nr. 14, S. 5567 - 5571Online Volltext: dx.doi.org/ (Open Access)
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Auto-inhibition of Mif2/CENP-C ensures centromere-dependent kinetochore assembly in budding yeastIn: The EMBO Journal Jg. 39 (2020) Nr. 14, S. e102938Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in actin polymerizationIn: Biological Chemistry Jg. 401 (2020) Nr. 8, S. 955 - 968Online Volltext: dx.doi.org/ (Open Access)
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The other side of the corona : Nanoparticles inhibit the protease taspase1 in a size-dependent mannerIn: Nanoscale Jg. 12 (2020) Nr. 37, S. 19093 - 19103Online Volltext: dx.doi.org/
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NMR Spectroscopy of supramolecular chemistry on protein surfacesIn: Beilstein Journal of Organic Chemistry Jg. 16 (2020) S. 2505 - 2522Online Volltext: dx.doi.org/ (Open Access)
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Backbone and side-chain chemical shift assignments of full-length, apo, human Pin1, a phosphoprotein regulator with interdomain allosteryIn: Biomolecular NMR Assignments Jg. 13 (2019) Nr. 1, S. 85 - 89Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Solution NMR Spectroscopy with Isotope-Labeled Cysteine (¹³C and ¹⁵N) Reveals the Surface Structure of l -Cysteine-Coated Ultrasmall Gold Nanoparticles (1.8 nm)In: Langmuir Jg. 35 (2019) Nr. 3, S. 767 - 778Online Volltext: dx.doi.org/
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Multivalent Ligands with Tailor-Made Anion Binding Motif as Stabilizers of Protein–Protein InteractionsIn: ChemBioChem Jg. 20 (2019) Nr. 23, S. 2921 - 2926Online Volltext: dx.doi.org/
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Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPaseIn: Biomolecules Jg. 9 (2019) Nr. 12, 876Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Structural Analysis of the 42 kDa Parvulin of Trypanosoma bruceiIn: Biomolecules Jg. 9 (2019) Nr. 3, 93Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Click chemistry on the surface of ultrasmall gold nanoparticles (2 nm) for covalent ligand attachment followed by nmr spectroscopyIn: Langmuir Jg. 35 (2019) Nr. 22, S. 7191 - 7204Online Volltext: dx.doi.org/
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Rationally designed DNA-origami hosts for protein guest
Nantech2019, Nucleic Acid Nanotechnology: from algorithmic design to biochemical applications, Aalto University, Espoo, Finland May 27-29, 2019,(2019) -
Structure and function of the human parvulins Pin1 and Par14/17In: Biological Chemistry Jg. 399 (2018) Nr. 2, S. 101 - 125Online Volltext: dx.doi.org/ (Open Access)
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Cell entry of a host-targeting protein of oomycetes requires gp96In: Nature Communications Jg. 9 (2018) Nr. 1, S. 2347Online Volltext: dx.doi.org/ (Open Access)
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The RxLR motif of the host targeting effector AVR3a of phytophthora infestans is cleaved before secretionIn: The Plant Cell Jg. 29 (2017) Nr. 6, S. 1184 - 1195Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1In: PLoS ONE Jg. 11 (2016) Nr. 3, S. e0151431Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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NmPin from the marine thaumarchaeote Nitrosopumilus maritimus is an active membrane associated prolyl isomeraseIn: BMC Biology (incorporating Journal of Biology) Jg. 14 (2016) Nr. 1, S. 53Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Molecular tweezers target a protein-protein interface and thereby modulate complex formationIn: Chemical Communications: ChemComm Jg. 52 (2016) Nr. 98, S. 14141 - 14144Online Volltext: dx.doi.org/ (Open Access)
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Determinants of tyrosylprotein sulfation coding and substrate specificity of tyrosylprotein sulfotransferases in metazoansIn: Chemico-Biological Interactions Jg. 259 (2016) Nr. Part A, S. 17 - 22Online Volltext: dx.doi.org/
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Heterodimers of Tyrosylprotein Sulfotransferases Suggest Existence of a Higher Organization Level of Transferases in the Membrane of the trans-Golgi ApparatusIn: Journal of Molecular Biology (JMB) Jg. 427 (2015) Nr. Issue 6, Part B, S. 1404 - 1412Online Volltext: dx.doi.org/
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Structural model of the bilitranslocase transmembrane domain supported by NMR and FRET dataIn: PLoS ONE Jg. 10 (2015) Nr. 8, S. e0135455Online Volltext: dx.doi.org/ (Open Access)
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The N-terminal region of the ubiquitin regulatory X (UBX) domain-containing protein 1 (UBXD1) modulates interdomain communication within the valosin-containing protein p97In: The Journal of Biological Chemistry (JBC) Jg. 290 (2015) Nr. 49, S. 29414 - 29427Online Volltext: dx.doi.org/ (Open Access)
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Human DNA-binding peptidyl-prolyl cis/trans isomerase Par14 is cell cycle dependently expressed and associates with chromatin in vivoIn: BMC Biochemistry Jg. 16 (2015) Nr. 1,Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Peptidyl succinimidyl peptides as taspase 1 inhibitorsIn: ChemBioChem Jg. 15 (2014) Nr. 15, S. 2233 - 2237Online Volltext: dx.doi.org/
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HumanbiologieIn: UTB Stuttgart Jg. 4130 (2014) 446 Seiten
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Design of a Modular Protein-Based MRI Contrast Agent for Targeted ApplicationIn: PLoS ONE Jg. 8 (2013) Nr. 6, S. e65346Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Transient domain interactions enhance the affinity of the mitotic regulator pin1 toward phosphorylated peptide ligandsIn: Structure Jg. 21 (2013) Nr. 10, S. 1769 - 1777Online Volltext: dx.doi.org/ (Open Access)
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Identification and characterization of peptides that bind the PPIase domain of Parvulin17In: Journal of Peptide Science Jg. 19 (2013) Nr. 6, S. 362 - 369Online Volltext: dx.doi.org/
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Host-targeting protein 1 (SpHtp1) from the oomycete Saprolegnia parasitica translocates specifically into fish cells in a tyrosine-O-sulphate-dependent mannerIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 109 (2012) Nr. 6, S. 2096 - 2101Online Volltext: dx.doi.org/
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Structure of the corrinoid : coenzyme M methyltransferase MtaA from Methanosarcina mazeiIn: Acta Crystallographica Section D: Biological Crystallography Jg. 68 (2012) Nr. 11, S. 1549 - 1557Online Volltext: dx.doi.org/
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Document Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasmIn: PLoS ONE Jg. 7 (2012) Nr. 1, S. e29559Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Single-Domain Parvulins Constitute a Specific Marker for Recently Proposed Deep-Branching Archaeal SubgroupsIn: Evolutionary Bioinformatics Jg. 7 (2011) S. 135 - 148Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Structure and Dynamics of the First Archaeal Parvulin Reveal a New Functionally Important Loop in Parvulin-type Prolyl IsomerasesIn: The Journal of Biological Chemistry (JBC) Jg. 286 (2011) S. 6554 - 6565Online Volltext: dx.doi.org/ (Open Access)
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A potential transcriptional regulator is out-of-frame translated from the metallothionein 2A messenger RNAIn: Analytical Biochemistry Jg. 409 (2011) Nr. 1, S. 159 - 161Online Volltext: dx.doi.org/
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Crystallographic Proof for an Extended Hydrogen Bonding Network in Small Prolyl IsomerasesIn: Journal of the American Chemical Society: JACS Jg. 133 (2011) Nr. 50, S. 20096 - 20099Online Volltext: dx.doi.org/ Online Volltext
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The solution structure of pGolemi, a high affinity Mena EVH1 binding miniature protein, suggests explanations for paralog-specific binding to Ena/VASP homology (EVH) 1 domainsIn: Biological Chemistry Jg. 390 (2009) Nr. 5-6, S. 417 - 426Online Volltext: dx.doi.org/
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Wie Proteine sich erkennen ... : ... und man ihnen dabei zusehen kann!In: Unikate: Berichte aus Forschung und Lehre (2009) Nr. 36: Naturwissenschaften/Medizin : Kernmagnetische Resonanz, S. 28 - 35Online Volltext: dx.doi.org/ Online Volltext (Open Access)
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Small family with key contacts : par14 and par17 parvulin proteins, relatives of pin1, now emerge in biomedical researchIn: Perspectives in Medicinal Chemistry Jg. 2 (2008) S. 11 - 20Online Volltext: dx.doi.org/ (Open Access)
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The DNA binding parvulin Par17 is targeted to the mitochondrial matrix by a recently evolved prepeptide uniquely present in Hominidae.In: BMC Biology (incorporating Journal of Biology) Jg. 5 (2007) S. 37Online Volltext: dx.doi.org/
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15N magnetic relaxation study of backbone dynamics of the ribosomeassociated cold shock response protein Yfia of Escherichia coliIn: Acta Biochimica Polonica Jg. 54 (2007) Nr. 4, S. 769 - 775(Open Access)
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GTP-Ras disrupts the intramolecular complex of C1 and RA domains of Nore1.In: Structure Jg. 14 (2006) S. 881 - 888Online Volltext: dx.doi.org/ (Open Access)
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Isotopic labelling of recombinant proteins expressed in the protozoan host Leishmania tarentolae.In: Protein Expression & Purification Jg. 48 (2006) S. 167 - 172
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Characterization of novel elongated Parvulin isoforms that are ubiquitously expressed in human tissues and originate from alternative transcription initiation.In: BMC Molecular Biology Jg. 7 (2006) S. 9
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Human TPST1 Transmembrane Domain Triggers Enzyme Dimerisation and Localisation to the Golgi CompartmentIn: Journal of Molecular Biology (JMB) Jg. 361 (2006) Nr. 3, S. 436 - 449Online Volltext: dx.doi.org/
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Specification of SUMO1- and SUMO2-interacting motifsIn: The Journal of Biological Chemistry (JBC) Jg. 281 (2006) Nr. 23, S. 16117 - 16127Online Volltext: dx.doi.org/ (Open Access)
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Identification of hPin1 inhibitors that induce apoptosis in a mammalian Ras transformed cell lineIn: Chemical Communications: ChemComm Jg. 4 (2005) S. 516 - 518Online Volltext: dx.doi.org/
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The crystal structure of human PAPS synthetase 1 reveals asymmetry in substrate bindingIn: Journal of Molecular Biology (JMB) Jg. 347 (2005) Nr. 3, S. 623 - 635Online Volltext: dx.doi.org/
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Book Review: Protein Structure: Determination, Analysis, and Applications for Drug Discovery. Edited by Daniel I. ChasmanIn: ChemBioChem Jg. 5 (2004) Nr. 4, S. 547 - 548Online Volltext: dx.doi.org/
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Expression, purification and crystallization of human 3′- phosphoadenosine-5′-phosphosulfate synthetase 1In: Acta Crystallographica Section D: Structural Biology Jg. 60 (2004) Nr. 2, S. 350 - 352Online Volltext: dx.doi.org/
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Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescensIn: Proceedings of the National Academy of Sciences of the United States of America Jg. 101 (2004) Nr. 47, S. 16431 - 16436Online Volltext: dx.doi.org/ (Open Access)
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Phosphorylation of the N-terminal domain regulates subcellular localization and DNA binding properties of the peptidyl-prolyl cis/trans isomerase hPar14In: Journal of Molecular Biology (JMB) Jg. 330 (2003) Nr. 5, S. 955 - 966Online Volltext: dx.doi.org/
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Structural analysis of the mitotic regulator hPin1 in solution : insights into domain architecture and substrate bindingIn: The Journal of Biological Chemistry (JBC) Jg. 278 (2003) Nr. 28, S. 26183 - 26193Online Volltext: dx.doi.org/ (Open Access)
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Die Vorliebe für Physik und die StrukturbiologieIn: Nachrichten aus der Chemie Jg. 51 (2003) Nr. 9, S. 917 - 917Online Volltext: dx.doi.org/
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Structural attributes in the conjugation of Ubiquitin, RUB and SUMO to protein substrates.In: Frontiers in Bioscience Jg. 7 (2002) S. 148 - 162
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A molecular handshakeIn: Trends in Biochemical Sciences Jg. 27 (2002) Nr. 10, S. 502 - 503Online Volltext: dx.doi.org/
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Induction of tyrosylprotein sulfotransferase isoform shift in human endothelial cellsIn: Circulation Jg. 106 (2002) Nr. Suppl. 2, S. 287
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The N-terminal basic domain of human parvulin h Par14 is responsible for the entry to the nucleus and high-affinity DNA-bindingIn: Journal of Molecular Biology (JMB) Jg. 321 (2002) Nr. 2, S. 235 - 247Online Volltext: dx.doi.org/
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Solution structure of the ribosome-associated cold shock response protein Yfia of Escherichia coliIn: Biochemical and Biophysical Research Communications (BBRC) Jg. 299 (2002) Nr. 5, S. 710 - 714Online Volltext: dx.doi.org/
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Shear stress mediates tyrosylprotein sulfotransferase isoform shift in human endothelial cellsIn: Biochemical and Biophysical Research Communications (BBRC) Jg. 294 (2002) Nr. 3, S. 541 - 546Online Volltext: dx.doi.org/
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Letter to the Editor: ¹H, ¹³C and ¹⁵N resonance assignments of the ribosome-associated cold shock response protein Yfia of Escherichia coliIn: Journal of Biomolecular NMR Jg. 23 (2002) Nr. 4, S. 335 - 336Online Volltext: dx.doi.org/
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A NMR-spectra based scoring function for protein dockingIn: Proceedings of the Fifth Annual International Conference on Computational Biology / RECOMB01: The Fifth Annual International Conference on Computational Molecular Biology, Montreal, Quebec, Canada, April 22 - 25, 2001 / Lengauer, Thomas (Hrsg.) 2001, S. 184 - 192Online Volltext: dx.doi.org/
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Delta: a mitogenic regulator of human hematopoesisIn: Trends in Biochemical Sciences Jg. 26 (2001) Nr. 5, S. 281Online Volltext: dx.doi.org/
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ATP, a trigger for pain-signalingIn: Trends in Biochemical Sciences Jg. 26 (2001) Nr. 1, S. 12Online Volltext: dx.doi.org/
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TonB – a mediator of iron uptake in bacteriaIn: Trends in Biochemical Sciences Jg. 26 (2001) Nr. 8, S. 472Online Volltext: dx.doi.org/