Research AG Voskuhl
The research of the Voskuhl group is focused on the synthesis, characterization and application of novel supramolecular systems for biological and medical issues.
Novel fluorophores for protein recognition
One topic of workinggroup Voskuhl is the synthesis of novel fluorophores for the recognition of proteins. These fluorophores should be synthesized in such a way that a fluorescence signal is generated only if a specific binding to the corresponding protein takes place.
Fig.1: Schematic representation of the binding of non-emissive binding partners to proteins to create a binding-induced fluorescence signal.
Another approach is to incorporate so-called photosensitizers in novel supramolecular structures that can form a highly reactive oxygen species upon irradiation with light. These structures then could find an application in the so-called photodynamic therapy (PDT) which is used for the selective treatment of cancer tumors.
Fig.2: Schematic representaiton of the formation of supramolecular polymers consisting photosensitiziers.