CRC1093 - Publications Project B7

Area B: Biological Targets

Publications by Prof. Dr. Stefan Westermann

Project B7:
Manipulation of the kinetochore-microtubule interface by supramolecular ligands

A. Dudziak, L. Engelhard, C. Bourque, B. U. Klink, P. Rombaut, N. Kornakov, K. Jänen, F. Herzog, C. Gatsogiannis, S. Westermann: Phospho-regulated Bim1/EB1 interactions trigger Dam1c ring assembly at the budding yeast outer kinetochore. EMBO J 2021 Jul 27:e108004. doi: 10.15252/embj.2021108004.

M. Böhm, K. Killinger, A. Dudziak, P. Pant, K. Jänen, S. Hohoff, K. Mechtler, M. Örd, M. Loog , E. Sanchez-Garcia , S. Westermann: Cdc4 phospho-degrons allow differential regulation of Ame1CENP-U protein stability across the cell cycle. Elife 2021 Jul 26;10:e67390. doi: 10.7554/eLife.67390.

N. Kornakov, B. Mollers, S. Westermann: The EB1-Kinesin-14 complex is required for efficient metaphase spindle assembly and kinetochore bi-orientation. J Cell Biol 2020 Oct 7, 219 (12): e202003072. doi: 10.1083/jcb.202003072

K. Killinger, M. Böhm, P. Steinbach, G. Hagemann, M. Blüggel, K. Jänen, S. Hohoff, P. Bayer, F. Herzog, S. Westermann: Auto-inhibition of Mif2/CENP-C Ensures Centromere-Dependent Kinetochore Assembly in Budding Yeast. EMBO J 2020 Jun 9;e102938, doi: 10.15252/embj.2019102938.

G. P. Altunkaya, F. Malvezzi, Z. Demianova, T. Zimniak, G. Litos, F. Weissmann, K. Mechtler, F. Herzog, and S. Westermann: CCAN assembly configures composite binding interfaces to promote cross-linking of Ndc80 complexes at the kinetochore. Current Biology, 2016, 26, pp. 2370-2378.

M. I. Molodtsov, C. Mieck, J. Dobbelaere, A. Dammermann, S. Westermann* and A. Vaziri*: A force-induced directional switch in a molecular motor enables parallel microtubule bundle formation. Cell. 2016, 167, pp 539-552. *co-corresponding authors

C. Mieck, M. I. Molodtsov, K. Drzewicka, B. van der Vaart, G. Litos, G. Schmauss, A. Vaziri and S. Westermann: Non-catalytic motor domains enable processive movement and functional diversification of the kinesin-14 Kar3. Elife 2015, Jan27; 4.doi:10.7554/eLife.04489.