Principal Investigators

Area A - Chemical Ligands and Methods

A1: Protein-recognition by supramolecular ligands from focused combinatorial libraries

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Since August 2019 the project is supervised by Prof. Dr. Jens Voskuhl and Prof. Dr. Thomas Schrader

Prof. Dr. Carsten Schmuck

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Organic Chemistry
Faculty of Chemistry
University of Duisburg-Essen

A2: Natural products as starting structures for the development of supramolecular ligands

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Prof. Dr. Markus Kaiser

Phone: +49 201 183 4980
Email

Chemical Biology

Centre for Medical Biotechnology (ZMB)
Faculty of Biology
University of Duisburg-Essen

A3: Designed copolymers and molecular tweezers for protein surface recognition

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Prof. Dr. Thomas Schrader

Phone: +49 201 183 3081
Email

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Organic Chemistry
Faculty of Chemistry
University of Duisburg-Essen

A5: Protein-specific nanoparticles for cellular uptake

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Prof. Dr. Matthias Epple

Phone: +49 201 183 2413
Email

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Inorganic Chemistry
Faculty of Chemistry
University of Duisburg-Essen

A6: DNA-based nanocontainers for predesigned spatial confinement of proteins

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Prof. Dr. Barbara Saccà

Phone: +49 201 183 3097
Email

Bionanotechnology

Centre for Medical Biotechnology (ZMB)
Faculty of Biology
University of Duisburg-Essen

A7: Pareto-optimization of protein-surface targeting supramolecular binders with hetero-avidity

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Prof. Dr. Daniel Hoffmann

Phone: +49 201 183 4391
Email

Bioinformatics

Centre for Medical Biotechnology (ZMB)
Faculty of Biology
University of Duisburg-Essen

A8: Exploring protein-recognition by supramolecular binders with MD an QM/MM methods

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Prof. Dr. Elsa Sánchez-Garcia

Phone: +49 201 183 3839
Email

Computational Biochemistry

Centre for Medical Biotechnology (ZMB)
Faculty of Biology
University of Duisburg-Essen

A9: Raman spectroscopic monitoring of protein recognition by supramolecular ligands

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Prof. Dr. Sebastian Schlücker

Phone: +49 201 183 6843
Email

Physical Chemistry

Faculty of Chemistry
University of Duisburg-Essen

A10: Novel luminophores with aggregation induced emission properties for protein recognition

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Prof. Dr. Jens Voskuhl

Phone: +49 201 183 2404
Email

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Biosupramolecular Chemistry

A11: Precision macromolecules for the sequence-controlled presentation of supramolecular ligands

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Prof. Dr. Laura Hartmann

Phone: +49 211 811 0360
Email

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Macromolecular Chemistry

Area B - Biological Targets

B1: Supramolecular ligand modulate assembly and function of HtrA proteases

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Prof. Dr. Michael Ehrmann

Phone: +49 201 183 2949
Email

Microbiology II

Centre for Medical Biotechnology (ZMB)
Faculty of Biology
University of Duisburg-Essen

B2: Probing mechanisms of the Cdo48/p97 segregase with designed supramolecular ligands

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Prof. Dr. Hemmo Meyer

Phone: +49 201 183 4217
Email

Molecular Biology I

Centre for Medical Biotechnology (ZMB)
Faculty of Biology
University of Duisburg-Essen

B4: Modulation of 14-3-3 protein-protein interactions by supramolecular chemistry

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Prof. Christian Ottmann

Phone: +31 40 247-2835
Email

Department of Biomedical Engineering

Eindhoven University of Technology

Faculty of Chemistry

University of Duisburg-Essen

B5: Dissection and modulation of (patho)biological Survivin functions by supramolecular ligands

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Prof. Dr. Shirley Knauer

Phone: +49 201 183 4987
Email

Molecular Biology II

Centre for Medical Biotechnology (ZMB)
Faculty of Biology
University of Duisburg-Essen

B6: Targeting centromer recuitment of mitotic regulators by supramolecular ligands

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Hon. Prof. Dr. Andrea Musacchio

Phone: +49 231 133-2101
Email

Department of Mechanistic Cell Biology

Max-Planck-Institut für molekulare Physiologie

B7: Manipulation of the kinetochore-microtubule interface by supramoleular ligands

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Prof. Dr. Stefan Westermann

Phone: +49 201 183 2404
Email

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Molecular Genetics, ZMB, Faculty of Biology

AM1: Modulating Chaperone-Client Protein Complexes

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Dr. Doris Hellerschmied

Phone: +49 201 183 3120
Email

Mechanistic Cell Biology

ZMB, Faculty of Biology

Area Z - Central Service

Z2: X-Ray Crystallography

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Dr. Ingrid Vetter

Phone: +49 231 133-2737
Email

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Max-Planck-Institut für molekulare Physiologie

Z3: NMR Spectroscopy

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Prof. Dr. Peter Bayer

Phone: +49 201 183 4677
Email

Structural and Medicinal Biochemistry

Centre for Medical Biotechnology (ZMB)
Faculty of Biology
University of Duisburg-Essen