ZMB Member Peter Bayer

ZMB Member
Peter Bayer

Next ZMB-Member
portrait photo of ZMB member Peter Bayer
© UDE/P.Bayer

Prof. Dr. Peter Bayer

Group

Structural and Medicinal Biochemistry

Faculty of Biology
University of Duisburg-Essen
Universitätsstr. 2
45141 Essen

Research Overview

The department Structural and Medicinal Biochemistry focuses on the elucidation of protein-protein and protein-ligand interactions using biochemical and biophysical strategies in addition to NMR as the main tool for the structure determination of biomolecules. Our research is geared towards predominantly human enzymes/proteins and their macromolecular complexes involved in posttranslational modification processes.

  1. Protein Structure Determination
  2. Biochemical Characterisation of Parvulins
  3. Biophysical studies on the interaction of synthetic supramolecular ligands and proteins
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Selected Publications

    Journal articles

  • Hommel, Katrin; Theisen, Sebastian; Blueggel, Mike; Niemeyer, Felix C.; Beuck, Christine; Bayer, Peter; Zadmard, Reza; Schrader, Thomas; Knauer, Shirley K.
    Highly Preorganized Calixarene Tweezers for Protein Recognition.
    In: Biomacromolecules, Vol. 26, 2025, Nr. 8, pp. 5310 – 5319
    DOI
  • Kirupakaran, Abbna; van den Boom, Johannes; Blueggel, Mike; Beuck, Christine; Niemeyer, Felix; Hayduk, Matthias; Balszuweit, Jan; Bayer, Peter; Voskuhl, Jens; Meyer, Hemmo; Schrader, Thomas
    Molecular Tweezers Block the Functional Pore of a Protein Machine
    In: Journal of the American Chemical Society: JACS, Vol. 147, 2025, Nr. 20, pp. 16836 – 16849
    DOI (Open Access)
  • Bietti, Antonio; Kauth, Alisa-Maite; Hommel, Katrin; Blüggel, Mike; Mohr, Laurenz; Niemeyer, Felix; Beuck, Christine; Bayer, Peter; Knauer, Shirley; Ravoo, Bart Jan; Schrader, Thomas
    Molecular Tweezers with Built-in Photoswitches Modulate Protein Activity
    In: RSC Chemical Biology, 2025, in press
    DOI (Open Access)
  • Bietti, Antonio L. Figueroa; Kauth, Alisa-Maite A.; Hommel, Katrin; Blueggel, Mike; Mohr, Laurenz; Niemeyer, Felix C.; Beuck, Christine; Bayer, Peter; Knauer, Shirley K.; Jan Ravoo, Bart; Schrader, Thomas
    Photoresponsive molecular tweezers modulate Taspase 1 activity
    In: RSC Chemical Biology, 2025, in press
    DOI (Open Access)
  • Kost, Niklas; Prymak, Oleg; Loza, Kateryna; Beuck, Christine; Bayer, Peter; Weidenthaler, Claudia; Heggen, Marc; Oliveira, Cristiano L. P.; Epple, Matthias
    Synthesis and characterization of dodecylamine-capped ultrasmall metallic palladium nanoparticles (2 nm)
    In: Nanoscale Advances, 2025, in press
    DOI (Open Access)
  • Kost, Niklas; Prymak, Oleg; Loza, Kateryna; Heggen, Marc; Oliveira, Cristiano L. P.; Beuck, Christine; Bayer, Peter; Epple, Matthias
    Synthesis and characterization of ultrasmall rhenium nanoparticles (1.5 nm)
    In: Journal of Nanoparticle Research, Vol. 27, 2025, Nr. 8, 218
    DOI (Open Access)
  • Wagner, Lisa-Sofie; Huber, Alexander; Loza, Kateryna; Beuck, Christine; Heggen, Marc; Bayer, Peter; Voskuhl, Jens; Epple, Matthias
    Temperature‐Resolved Fluorescence Quenching on Ultrasmall Gold Nanoparticles Conjugated with Dye‐Labeled Peptides
    In: Nano Select, 2025, in press
    DOI (Open Access)
  • Sternberg, Anna; Borger, Jennifer Lynne; Thies, Mathilda; Matena, Anja; Blüggel, Mike; Kamba, Bianca; Beuck, Christine; Kaschani, Farnusch; Kaiser, Markus; Bayer, Peter
    The Actin‐Binding Prolyl‐Isomerase Par17 Sustains Its Substrate Selectivity by Interdomain Allostery
    In: Proteins: Structure, Function and Genetics, Vol. 93, 2025, Nr. 9, pp. 1481 – 1497
    DOI (Open Access)
  • Wagner, Lisa-Sofie; Thiele, Tobias; Loza, Kateryna; Beuck, Christine; Bayer, Peter; Heggen, Marc; Giese, Michael R. A.; Epple, Matthias
    Ultrasmall Gold Nanoparticles (2 nm) Decorated with a High Density of Photochemically Switchable Ligands
    In: Chemistry - A European Journal, 2025
    DOI (Open Access)
  • Hommel, Katrin; Kauth, Alisa-Maite A.; Kirupakaran, Abbna; Theisen, Sebastian; Hayduk, Matthias; Niemeyer, Felix C.; Beuck, Christine; Zadmard, Reza; Bayer, Peter; Jan Ravoo, Bart; Voskuhl, Jens; Schrader, Thomas; Knauer, Shirley K.
    Functional Linkers Support Targeting of Multivalent Tweezers to Taspase1
    In: Chemistry - A European Journal, Vol. 30, 2024, Nr. 56, e202401542
    DOI (Open Access)
  • Wolff, Natalie; Białas, Nataniel; Loza, Kateryna; Heggen, Marc; Schaller, Torsten; Niemeyer, Felix; Weidenthaler, Claudia; Beuck, Christine; Bayer, Peter; Prymak, Oleg; Oliveira, Cristiano L. P.; Epple, Matthias
    Increased Cytotoxicity of Bimetallic Ultrasmall Silver–Platinum Nanoparticles (2 nm) on Cells and Bacteria in Comparison to Silver Nanoparticles of the Same Size
    In: Materials, Vol. 17, 2024, Nr. 15, 3702
    DOI (Open Access)
  • Wagner, Lisa-Sofie; Prymak, Oleg; Schaller, Torsten; Beuck, Christine; Loza, Kateryna; Niemeyer, Felix; Gumbiowski, Nina; Kostka, Kathrin; Bayer, Peter; Heggen, Marc; Oliveira, Cristiano L. P.; Epple, Matthias
    The Molecular Footprint of Peptides on the Surface of Ultrasmall Gold Nanoparticles (2 nm) Is Governed by Steric Demand
    In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry, Vol. 128, 2024, Nr. 17, pp. 4266 – 4281
    DOI
  • Neblik, Jonas; Kirupakaran, Abbna; Beuck, Christine; Mieres-Perez, Joel; Niemeyer, Felix; Le, My-Hue; Telgheder, Ursula; Schmuck, Jessica Felice; Dudziak, Alexander; Bayer, Peter; Sanchez-Garcia, Elsa; Westermann, Stefan; Schrader, Thomas
    Multivalent Molecular Tweezers Disrupt the Essential NDC80 Interaction with Microtubules
    In: Journal of the American Chemical Society: JACS, Vol. 145, 2023, Nr. 28, pp. 15251 – 15264
    DOI
  • Seiler, Theresa; Lennartz, Annika; Klein, Kai; Hommel, Katrin; Figueroa Bietti, Antonio; Hadrovic, Inesa; Kollenda, Sebastian; Sager, Jonas; Beuck, Christine; Chlosta, Emilia; Bayer, Peter; Juul-Madsen, Kristian; Vorup-Jensen, Thomas; Schrader, Thomas; Epple, Matthias; Knauer, Shirley; Hartmann, Laura
    Potentiating Tweezer Affinity to a Protein Interface with Sequence-Defined Macromolecules on Nanoparticles
    In: Biomacromolecules, Vol. 24, 2023, Nr. 8, pp. 3666 – 3679
    DOI
  • Blüggel, Mike; Kröning, Alexander; Kracht, Matthias; van den Boom, Johannes; Dabisch, Matthias; Göhring, Anna; Kaschani, Farnusch; Kaiser, Markus; Bayer, Peter; Meyer, Hemmo; Beuck, Christine
    The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPase
    In: Nature Communications, Vol. 14, 2023, Nr. 1, 3258
    DOI, Online Full Text (Open Access)
  • Wolff, Natalie; Loza, Kateryna; Heggen, Marc; Schaller, Torsten; Niemeyer, Felix; Bayer, Peter; Beuck, Christine; Oliveira, Cristiano L P; Prymak, Oleg; Weidenthaler, Claudia; Epple, Matthias
    Ultrastructure and Surface Composition of Glutathione-Terminated Ultrasmall Silver, Gold, Platinum, and Alloyed Silver-Platinum Nanoparticles (2 nm)
    In: Inorganic Chemistry, Vol. 62, 2023, Nr. 42, pp. 17470 – 17485
    DOI
  • Warmerdam, Zoey; Kamba, Bianca; Le, My-Hue; Schrader, Thomas; Isaacs, Lyle; Bayer, Peter; Hof, Fraser
    Binding Methylarginines and Methyllysines as Free Amino Acids : A Comparative Study of Multiple Host Classes
    In: ChemBioChem, Vol. 23, 2022, Nr. 2, e202100502
    DOI (Open Access)
  • Höing, Alexander; Struth, Robin; Beuck, Christine; Rafieiolhosseini, Neda; Hoffmann, Daniel; Stauber, Roland H.; Bayer, Peter; Niemeyer, Jochen; Knauer, Shirley
    Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligand
    In: RSC Advances, Vol. 12, 2022, Nr. 53, pp. 34176 – 34184
    DOI (Open Access)
  • Höing, Alexander; Kirupakaran, Abbna; Beuck, Christine; Pörschke, Marius; Niemeyer, Felix; Seiler, Theresa; Hartmann, Laura; Bayer, Peter; Schrader, Thomas; Knauer, Shirley
    Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular Tweezers
    In: Biomacromolecules, Vol. 23, 2022, Nr. 11, pp. 4504 – 4518
    DOI
  • Wetzel, Oliver; Prymak, Oleg; Loza, Kateryna; Gumbiowski, Nina; Heggen, Marc; Bayer, Peter; Beuck, Christine; Weidenthaler, Claudia; Epple, Matthias
    Water-Based Synthesis of Ultrasmall Nanoparticles of Platinum Group Metal Oxides (1.8 nm)
    In: Inorganic Chemistry, Vol. 61, 2022, Nr. 12, pp. 5133 – 5147
    DOI
  • Wetzel, Oliver; Hosseini, Shabnam; Loza, Kateryna; Heggen, Marc; Prymak, Oleg; Bayer, Peter; Beuck, Christine; Schaller, Torsten; Niemeyer, Felix; Weidenthaler, Claudia; Epple, Matthias
    Metal-Ligand Interface and Internal Structure of Ultrasmall Silver Nanoparticles (2 nm)
    In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry, Vol. 125, 2021, Nr. 21, pp. 5645 – 5659
    DOI
  • van der Meer, Selina Beatrice; Hadrovic, Inesa; Meiners, Annika; Loza, Kateryna; Heggen, Marc; Knauer, Shirley; Bayer, Peter; Schrader, Thomas; Beuck, Christine; Epple, Matthias
    New tools to probe the protein surface : Ultrasmall gold nanoparticles carry amino acid binders
    In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry, Vol. 125, 2021, Nr. 1, pp. 115 – 127
    DOI (Open Access)
  • Ruks, Tatjana; Loza, Kateryna; Heggen, Marc; Prymak, Oleg; Sehnem, Andre Luiz; Oliveira, Cristiano L. P.; Bayer, Peter; Beuck, Christine; Epple, Matthias
    Peptide-Conjugated Ultrasmall Gold Nanoparticles (2 nm) for Selective Protein Targeting
    In: ACS Applied Bio Materials, Vol. 4, 2021, Nr. 1, pp. 945 – 965
    DOI (Open Access)
  • Meiners, Annika; Bäcker, Sandra; Hadrovic, Inesa; Heid, Christian; Beuck, Christine; Ruiz-Blanco, Yasser B.; Mieres-Perez, Joel; Pörschke, Marius; Grad, Jean-Noël; Vallet, Cecilia; Hoffmann, Daniel; Bayer, Peter; Sánchez-García, Elsa; Schrader, Thomas; Knauer, Shirley
    Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezers
    In: Nature Communications, Vol. 12, 2021, Nr. 1, pp. 1505
    DOI, Online Full Text (Open Access)
  • Ruks, Tatjana; Loza, Kateryna; Heggen, Marc; Ottmann, Christian; Bayer, Peter; Beuck, Christine; Epple, Matthias
    Targeting the Surface of the Protein 14-3-3 by Ultrasmall (1.5 nm) Gold Nanoparticles Carrying the Specific Peptide CRaf
    In: ChemBioChem, Vol. 22, 2021, Nr. 8, pp. 1456 – 1463
    DOI (Open Access)
  • Killinger, Kerstin; Böhm, Miriam; Steinbach, Philine; Hagemann, Götz; Blüggel, Mike; Jänen, Karolin; Hohoff, Simone; Bayer, Peter; Herzog, Franz; Westermann, Stefan
    Auto-inhibition of Mif2/CENP-C ensures centromere-dependent kinetochore assembly in budding yeast
    In: The EMBO Journal, Vol. 39, 2020, Nr. 14, pp. e102938
    DOI, Online Full Text (Open Access)
  • Vallet, Cecilia; Aschmann, Dennis; Beuck, Christine; Killa, Matthias; Meiners, Annika; Mertel, Marcel; Ehlers, Martin; Bayer, Peter; Schmuck, Carsten; Giese, Michael R. A.; Knauer, Shirley
    Functional Disruption of the Cancer-Relevant Interaction between Survivin and Histone H3 with a Guanidiniocarbonyl Pyrrole Ligand
    In: Angewandte Chemie International Edition, Vol. 59, 2020, Nr. 14, pp. 5567 – 5571
    DOI (Open Access)
  • Bayer, Peter; Matena, Anja; Beuck, Christine
    NMR Spectroscopy of supramolecular chemistry on protein surfaces
    In: Beilstein Journal of Organic Chemistry, Vol. 16, 2020, pp. 2505 – 2522
    DOI (Open Access)
  • Göhring, Anna; Michin, Irina; Gerdes, Tina; Schulze, Nina; Blüggel, Mike; Rehic, Edisa; Kaschani, Farnusch; Kaiser, Markus; Bayer, Peter
    Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in actin polymerization
    In: Biological Chemistry, Vol. 401, 2020, Nr. 8, pp. 955 – 968
    DOI (Open Access)
  • van den Boom, Johannes; Hensel, Astrid; Trusch, Franziska; Matena, Anja; Siemer, Svenja; Guel, Désirée; Docter, Dominic; Höing, Alexander; Bayer, Peter; Stauber, Roland H.; Knauer, Shirley
    The other side of the corona : Nanoparticles inhibit the protease taspase1 in a size-dependent manner
    In: Nanoscale, Vol. 12, 2020, Nr. 37, pp. 19093 – 19103
    DOI
  • Born, Alexandra; Nichols, Parker J.; Henen, Morkos A.; Chi, Celestine N.; Strotz, Dean; Bayer, Peter; Tate, Shin-Ichi; Peng, Jeffrey W.; Vögeli, Beat
    Backbone and side-chain chemical shift assignments of full-length, apo, human Pin1, a phosphoprotein regulator with interdomain allostery
    In: Biomolecular NMR Assignments, Vol. 13, 2019, Nr. 1, pp. 85 – 89
    DOI, Online Full Text (Open Access)
  • van der Meer, Selina; Loza, Kateryna; Wey, Karolin; Heggen, Marc; Beuck, Christine; Bayer, Peter; Epple, Matthias
    Click chemistry on the surface of ultrasmall gold nanoparticles (2 nm) for covalent ligand attachment followed by nmr spectroscopy
    In: Langmuir, Vol. 35, 2019, Nr. 22, pp. 7191 – 7204
    DOI
  • Bartsch, Lina; Bartel, Maria; Gigante, Alba; Iglesias-Fernández, Javier; Ruiz-Blanco, Yasser B.; Beuck, Christine; Briels, Jeroen; Tötsch, Niklas; Bayer, Peter; Sánchez-García, Elsa; Ottmann, Christian; Schmuck, Carsten
    Multivalent Ligands with Tailor-Made Anion Binding Motif as Stabilizers of Protein–Protein Interactions
    In: ChemBioChem, Vol. 20, 2019, Nr. 23, pp. 2921 – 2926
    DOI
  • Ruks, Tatjana; Beuck, Christine; Schaller, Torsten; Niemeyer, Felix; Zähres, Manfred; Loza, Kateryna; Heggen, Marc; Hagemann, Ulrich; Mayer, Christian; Bayer, Peter; Epple, Matthias
    Solution NMR Spectroscopy with Isotope-Labeled Cysteine (¹³C and ¹⁵N) Reveals the Surface Structure of l -Cysteine-Coated Ultrasmall Gold Nanoparticles (1.8 nm)
    In: Langmuir, Vol. 35, 2019, Nr. 3, pp. 767 – 778
    DOI
  • Rehic, Edisa; Hönig, Dana; Kamba, Bianca; Göhring, Anna; Hofmann, Eckhard; Gasper, Raphael; Matena, Anja; Bayer, Peter
    Structural Analysis of the 42 kDa Parvulin of Trypanosoma brucei
    In: Biomolecules, Vol. 9, 2019, Nr. 3, 93
    DOI, Online Full Text (Open Access)
  • Blüggel, Mike; van den Boom, Johannes; Meyer, Hemmo; Bayer, Peter; Beuck, Christine
    Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPase
    In: Biomolecules, Vol. 9, 2019, Nr. 12, 876
    DOI, Online Full Text (Open Access)
  • Trusch, Franziska; Loebach, Lars; Wawra, Stephan; Durward, Elaine; Wuensch, Andreas; Iberahim, Nurul Aqilah; De Bruijn, Irene; MacKenzie, Kevin; Willems, Ariane; Toloczko, Aleksandra; Diéguez-Uribeondo, Javier; Rasmussen, Tim; Schrader, Thomas; Bayer, Peter; Secombes, Chris J.; Van West, Pieter
    Cell entry of a host-targeting protein of oomycetes requires gp96
    In: Nature Communications, Vol. 9, 2018, Nr. 1, pp. 2347
    DOI (Open Access)
  • Matena, Anja; Rehic, Edisa; Hönig, Dana; Kamba, Bianca; Bayer, Peter
    Structure and function of the human parvulins Pin1 and Par14/17
    In: Biological Chemistry, Vol. 399, 2018, Nr. 2, pp. 101 – 125
    DOI (Open Access)
  • Wawra, Stephan; Trusch, Franziska; Matena, Anja; Apostolakis, Kostis; Linne, Uwe; Zhukov, Igor; Stanek, Jan; Koźmiński, Wiktor; Davidson, Ian; Secombes, Chris J.; Bayer, Peter; van West, Pieter
    The RxLR motif of the host targeting effector AVR3a of phytophthora infestans is cleaved before secretion
    In: The Plant Cell, Vol. 29, 2017, Nr. 6, pp. 1184 – 1195
    DOI, Online Full Text (Open Access)
  • Hartmann-Fatu, Cristina; Bayer, Peter
    Determinants of tyrosylprotein sulfation coding and substrate specificity of tyrosylprotein sulfotransferases in metazoans
    In: Chemico-Biological Interactions, Vol. 259, 2016, Nr. Part A, pp. 17 – 22
    DOI
  • Trusch, Franziska; Kowski, Klaus; Bravo-Rodriguez, Kenny; Beuck, Christine; Sowislok, Andrea; Wettig, Burkhard; Matena, Anja; Sánchez-García, Elsa; Meyer, Hemmo; Schrader, Thomas; Bayer, Peter
    Molecular tweezers target a protein-protein interface and thereby modulate complex formation
    In: Chemical Communications: ChemComm, Vol. 52, 2016, Nr. 98, pp. 14141 – 14144
    DOI (Open Access)
  • Hoppstock, Lukas; Trusch, Franziska; Lederer, Christoph; van West, Pieter; Koenneke, Martin; Bayer, Peter
    NmPin from the marine thaumarchaeote Nitrosopumilus maritimus is an active membrane associated prolyl isomerase
    In: BMC Biology (incorporating Journal of Biology), Vol. 14, 2016, Nr. 1, pp. 53
    DOI, Online Full Text (Open Access)
  • van den Boom, Johannes; Trusch, Franziska; Hoppstock, Lukas; Beuck, Christine; Bayer, Peter
    Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1
    In: PLoS ONE, Vol. 11, 2016, Nr. 3, pp. e0151431
    DOI, Online Full Text (Open Access)
  • Hartmann-Fatu, Cristina; Trusch, Franziska; Moll, Carina; Michin, Irina; Hassinen, Antti; Kellokumpu, Sakari; Bayer, Peter
    Heterodimers of Tyrosylprotein Sulfotransferases Suggest Existence of a Higher Organization Level of Transferases in the Membrane of the trans-Golgi Apparatus
    In: Journal of Molecular Biology (JMB), Vol. 427, 2015, Nr. Issue 6, Part B, pp. 1404 – 1412
    DOI
  • Saningong, Akuma D.; Bayer, Peter
    Human DNA-binding peptidyl-prolyl cis/trans isomerase Par14 is cell cycle dependently expressed and associates with chromatin in vivo
    In: BMC Biochemistry, Vol. 16, 2015, Nr. 1
    DOI, Online Full Text (Open Access)
  • Roy Choudhury, Amrita; Sikorska, Emilia; van den Boom, Johannes; Bayer, Peter; Popenda, Lukasz; Szutkowski, Kosma; Jurga, Stefan; Bonomi, Massimiliano; Sali, Andrej; Zhukov, Igor; Passamonti, Sabina; Novič, Marjana
    Structural model of the bilitranslocase transmembrane domain supported by NMR and FRET data
    In: PLoS ONE, Vol. 10, 2015, Nr. 8, pp. e0135455
    DOI (Open Access)
  • Trusch, Franziska; Matena, Anja; Vuk, Maja; Körver, Lisa; Knævelsrud, Helene; Freemont, Paul S.; Meyer, Hemmo; Bayer, Peter
    The N-terminal region of the ubiquitin regulatory X (UBX) domain-containing protein 1 (UBXD1) modulates interdomain communication within the valosin-containing protein p97
    In: The Journal of Biological Chemistry (JBC), Vol. 290, 2015, Nr. 49, pp. 29414 – 29427
    DOI (Open Access)
  • van den Boom, Johannes; Mamic, Marija; Baccelliere, Daniele; Zweerink, Susanne; Kaschani, Farnusch; Knauer, Shirley; Bayer, Peter; Kaiser, Markus
    Peptidyl succinimidyl peptides as taspase 1 inhibitors
    In: ChemBioChem, Vol. 15, 2014, Nr. 15, pp. 2233 – 2237
    DOI
  • Grum, Daniel; Franke, Stefan; Kraff, Oliver; Heider, Dominik; Schramm, Alexander; Hoffmann, Daniel; Bayer, Peter
    Design of a Modular Protein-Based MRI Contrast Agent for Targeted Application
    In: PLoS ONE, Vol. 8, 2013, Nr. 6, pp. e65346
    DOI, Online Full Text (Open Access)
  • Elfaki, Imadeldin; Knitsch, Andre; Matena, Anja; Bayer, Peter
    Identification and characterization of peptides that bind the PPIase domain of Parvulin17
    In: Journal of Peptide Science, Vol. 19, 2013, Nr. 6, pp. 362 – 369
    DOI
  • Matena, Anja; Sinnen, Christian; van den Boom, Johannes; Wilms, Christoph; Dybowski, Jan Nikolaj; Maltaner, Ricarda; Müller, Jonathan W.; Link, Nina M.; Hoffmann, Daniel; Bayer, Peter
    Transient domain interactions enhance the affinity of the mitotic regulator pin1 toward phosphorylated peptide ligands
    In: Structure, Vol. 21, 2013, Nr. 10, pp. 1769 – 1777
    DOI (Open Access)
  • Schröder, Elisabeth; Gebel, Lena; Eremeev, Andrey A.; Morgner, Jessica; Grum, Daniel; Knauer, Shirley; Bayer, Peter; Müller, Jonathan W.
    Document Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasm
    In: PLoS ONE, Vol. 7, 2012, Nr. 1, pp. e29559
    DOI, Online Full Text (Open Access)
  • Wawra, Stephan; Bain, Judith; Durward, Elaine; De Bruijn, Irene; Minor, Kirsty L.; Matena, Anja; Löbach, Lars; Whisson, Stephen C.; Bayer, Peter; Porter, Andrew J.; Birch, Paul R. J.; Secombes, Chris J.; Van West, Pieter
    Host-targeting protein 1 (SpHtp1) from the oomycete Saprolegnia parasitica translocates specifically into fish cells in a tyrosine-O-sulphate-dependent manner
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 109, 2012, Nr. 6, pp. 2096 – 2101
    DOI
  • Hoeppner, Astrid; Thomas, Frank; Rueppel, Alma; Hensel, Reinhard; Blankenfeldt, Wulf; Bayer, Peter; Faust, Annette
    Structure of the corrinoid : coenzyme M methyltransferase MtaA from Methanosarcina mazei
    In: Acta Crystallographica Section D: Biological Crystallography, Vol. 68, 2012, Nr. 11, pp. 1549 – 1557
    DOI
  • Elfaki, Imadeldin; Bayer, Peter; Müller, Jonathan W.
    A potential transcriptional regulator is out-of-frame translated from the metallothionein 2A messenger RNA
    In: Analytical Biochemistry, Vol. 409, 2011, Nr. 1, pp. 159 – 161
    DOI
  • Müller, Jonathan W.; Link, Nina C; Matena, Anja; Hoppstock, Lukas; Rüppel, Alma; Bayer, Peter; Blankenfeldt, Wulf
    Crystallographic Proof for an Extended Hydrogen Bonding Network in Small Prolyl Isomerases
    In: Journal of the American Chemical Society: JACS, Vol. 133, 2011, Nr. 50, pp. 20096 – 20099
    DOI, Online Full Text
  • Lederer, Christoph; Heider, Dominik; van den Boom, Johannes; Hoffmann, Daniel; Müller, Jonathan W.; Bayer, Peter
    Single-Domain Parvulins Constitute a Specific Marker for Recently Proposed Deep-Branching Archaeal Subgroups
    In: Evolutionary Bioinformatics, Vol. 7, 2011, pp. 135 – 148
    DOI, Online Full Text (Open Access)
  • Jaremko, Lukasz; Jaremko, Mariusz; Elfaki, Imadeldin; Müller, Jonathan W.; Ejchart, Andrzej; Bayer, Peter; Zhukov, Igor
    Structure and Dynamics of the First Archaeal Parvulin Reveal a New Functionally Important Loop in Parvulin-type Prolyl Isomerases
    In: The Journal of Biological Chemistry (JBC), Vol. 286, 2011, pp. 6554 – 6565
    DOI (Open Access)
  • Link, Nina M.; Hunke, Cornelia; Müller, Jonathan W.; Eichler, Jutta; Bayer, Peter
    The solution structure of pGolemi, a high affinity Mena EVH1 binding miniature protein, suggests explanations for paralog-specific binding to Ena/VASP homology (EVH) 1 domains
    In: Biological Chemistry, Vol. 390, 2009, Nr. 5-6, pp. 417 – 426
    DOI
  • Müller, Jonathan W.; Bayer, Peter
    Small family with key contacts : par14 and par17 parvulin proteins, relatives of pin1, now emerge in biomedical research
    In: Perspectives in Medicinal Chemistry, Vol. 2, 2008, pp. 11 – 20
    DOI (Open Access)
  • Zhukov, Igor; Bayer, Peter; Schölermann, Beate; Ejchart, Andrzej
    15N magnetic relaxation study of backbone dynamics of the ribosomeassociated cold shock response protein Yfia of Escherichia coli
    In: Acta Biochimica Polonica, Vol. 54, 2007, Nr. 4, pp. 769 – 775
    (Open Access)
  • Kessler, Daniel; Papatheodorou, Panagiotis; Stratmann, Tina; Dian, Elke Andrea; Hartmann-Fatu, Cristina; Rassow, Joachim; Bayer, Peter; Müller, Jonathan W.
    The DNA binding parvulin Par17 is targeted to the mitochondrial matrix by a recently evolved prepeptide uniquely present in Hominidae
    In: BMC Biology (incorporating Journal of Biology), Vol. 5, 2007, 37
    DOI
  • Mueller, Jonathan Wolf; Kessler, Daniel; Neumann, Daniel; Stratmann, Tina; Papatheodorou, Panagiotis; Hartmann-Fatu, Cristina; Bayer, Peter
    Characterization of novel elongated Parvulin isoforms that are ubiquitously expressed in human tissues and originate from alternative transcription initiation
    In: BMC Molecular Biology, Vol. 7, 2006, 9
    DOI
  • Harjes, E.; Harjes, S.; Wohlgemuth, S.; Mueller, K.H.; Krieger, E.; Herrmann, C.; Bayer, Peter
    GTP-Ras disrupts the intramolecular complex of C1 and RA domains of Nore1.
    In: Structure, Vol. 14, 2006, pp. 881 – 888
    DOI (Open Access)
  • Goettsch, Sandra; Badea, Rodica A.; Müller, Jonathan W.; Wotzlaw, Christoph; Schoelermann, Beate; Schulz, Lars; Rabiller, Matthias; Bayer, Peter; Hartmann-Fatu, Cristina
    Human TPST1 Transmembrane Domain Triggers Enzyme Dimerisation and Localisation to the Golgi Compartment
    In: Journal of Molecular Biology (JMB), Vol. 361, 2006, Nr. 3, pp. 436 – 449
    DOI
  • Niculae, A.; Gruen, M.; Bayer, Peter; Breitling, R.; Alexandrov, K.
    Isotopic labelling of recombinant proteins expressed in the protozoan host Leishmania tarentolae.
    In: Protein Expression & Purification, Vol. 48, 2006, pp. 167 – 172
  • Hecker, Christina-Maria; Rabiller, Matthias; Haglund, Kaisa; Bayer, Peter; Dikic, Ivan
    Specification of SUMO1- and SUMO2-interacting motifs
    In: The Journal of Biological Chemistry (JBC), Vol. 281, 2006, Nr. 23, pp. 16117 – 16127
    DOI (Open Access)
  • Bayer, E.; Thutewohl, M.; Christner, C.; Waldmann, H.; Bayer, Peter
    Identification of hPin1 inhibitors that induce apoptosis in a mammalian Ras transformed cell line
    In: Chemical Communications: ChemComm, Vol. 4, 2005, pp. 516 – 518
    DOI
  • Harjes, Stefan; Bayer, Peter; Scheidig, Axel J.
    The crystal structure of human PAPS synthetase 1 reveals asymmetry in substrate binding
    In: Journal of Molecular Biology (JMB), Vol. 347, 2005, Nr. 3, pp. 623 – 635
    DOI
  • Harjes, Stefan; Scheidig, Axel; Bayer, Peter
    Expression, purification and crystallization of human 3′- phosphoadenosine-5′-phosphosulfate synthetase 1
    In: Acta Crystallographica Section D: Structural Biology, Vol. 60, 2004, Nr. 2, pp. 350 – 352
    DOI
  • Blankenfeldt, Wulf; Kuzin, Alexandre P.; Skarina, Tatiana; Korniyenko, Yuriy; Tong, Liang; Bayer, Peter; Janning, Petra; Thomashow, Linda S.; Mavrodi, Dmitri V.
    Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens
    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, 2004, Nr. 47, pp. 16431 – 16436
    DOI (Open Access)
  • Reimer, Tatiana; Weiwad, Matthias; Schierhorn, Angelika; Ruecknagel, Peter-Karl; Rahfeld, Jens-Ulrich; Bayer, Peter; Fischer, Gunter
    Phosphorylation of the N-terminal domain regulates subcellular localization and DNA binding properties of the peptidyl-prolyl cis/trans isomerase hPar14
    In: Journal of Molecular Biology (JMB), Vol. 330, 2003, Nr. 5, pp. 955 – 966
    DOI
  • Bayer, Elena; Goettsch, Sandra; Müller, Jonathan W.; Griewel, Bernhard; Guiberman, Elena; Mayr, Lorenz M.; Bayer, Peter
    Structural analysis of the mitotic regulator hPin1 in solution : insights into domain architecture and substrate binding
    In: The Journal of Biological Chemistry (JBC), Vol. 278, 2003, Nr. 28, pp. 26183 – 26193
    DOI (Open Access)
  • Goettsch, S.; Goettsch, W.; Morawietz, H.; Bayer, Peter
    Induction of tyrosylprotein sulfotransferase isoform shift in human endothelial cells
    In: Circulation, Vol. 106, 2002, Nr. Suppl. 2, pp. 287
  • Kalinin, Alexander; Rak, Alexej; Shcherbakov, Dmitry; Bayer, Peter
    Letter to the Editor: ¹H, ¹³C and ¹⁵N resonance assignments of the ribosome-associated cold shock response protein Yfia of Escherichia coli
    In: Journal of Biomolecular NMR, Vol. 23, 2002, Nr. 4, pp. 335 – 336
    DOI
  • Goettsch, Sandra; Goettsch, Winfried; Morawietz, Henning; Bayer, Peter
    Shear stress mediates tyrosylprotein sulfotransferase isoform shift in human endothelial cells
    In: Biochemical and Biophysical Research Communications (BBRC), Vol. 294, 2002, Nr. 3, pp. 541 – 546
    DOI
  • Rak, Alexey; Kalinin, Alexander; Shcherbakov, Dmitry; Bayer, Peter
    Solution structure of the ribosome-associated cold shock response protein Yfia of Escherichia coli
    In: Biochemical and Biophysical Research Communications (BBRC), Vol. 299, 2002, Nr. 5, pp. 710 – 714
    DOI
  • Goettsch, S.; Bayer, Peter
    Structural attributes in the conjugation of Ubiquitin, RUB and SUMO to protein substrates.
    In: Frontiers in Bioscience, Vol. 7, 2002, pp. 148 – 162
  • Surmacz, Tatiana Anna; Bayer, Elena; Rahfeld, Jens-Ulrich; Fischer, Gunter; Bayer, Peter
    The N-terminal basic domain of human parvulin h Par14 is responsible for the entry to the nucleus and high-affinity DNA-binding
    In: Journal of Molecular Biology (JMB), Vol. 321, 2002, Nr. 2, pp. 235 – 247
    DOI
  • Kipping, M.; Zarnt, T.; Kiessig, S.; Reimer, U.; Fischer, G.; Bayer, Peter
    Increased backbone flexibility in threonine
    In: Biochemistry, Vol. 40, 2001, Nr. 27, pp. 7957 – 7963
    DOI
  • Kohlbacher, Oliver; Burchardt, Andreas; Moll, Andreas; Hildebrandt, Andreas; Bayer, Peter; Lenhof, Hans-Peter
    Structure prediction of protein complexes by an NMR-based protein docking algorithm
    In: Journal of Biomolecular NMR, Vol. 20, 2001, Nr. 1, pp. 15 – 21
    DOI
  • Sekerina, E; Rahfeld, J U; Müller, J; Fanghänel, J; Rascher, C; Fischer, G; Bayer, Peter
    NMR solution structure of hPar14 reveals similarity to the peptidyl prolyl cis/trans isomerase domain of the mitotic regulator hPin1 but indicates a different functionality of the protein
    In: Journal of Molecular Biology (JMB), Vol. 301, 2000, Nr. 4, pp. 1003 – 1017
    DOI
  • Bayer, Peter; Varani, Luca; Varani, Gabriele
    Nuclear magnetic resonance methods to study RNA-protein complexes
    In: Methods in Enzymology, Vol. 317: RNA - Ligand Interactions, Part A, 2000, pp. 198 – 220
    DOI
  • Marx, Ute Charlotte; Adermann, Knut; Bayer, Peter; Forssmann, Wolf-Georg; Rösch, Paul
    Solution structures of human parathyroid hormone fragments hPTH(1-34) and hPTH(1-39) and bovine parathyroid hormone fragment bPTH(1-37)
    In: Biochemical and Biophysical Research Communications (BBRC), Vol. 267, 2000, Nr. 1, pp. 213 – 220
    DOI
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