Analytics Core Facility Essen
Organization
The Analytics Core Facility Essen (ACE) is a central facility of the Center of Medical Biotechnology (ZMB) and of the Faculty of Biology of the University Duisburg-Essen. It offers access to state-of-the-art mass spectrometry-based proteomics for internal and external users. The timely technical equipment of the ACE allows us to provide a wide variety of different “bottom-up” and “top-down” proteomics methods. Furthermore, we also develop innovative solutions for project-specific demands. The service comprises all aspects of mass spectrometry-based proteomics, starting from technical advice and project planning, sample preparation and analysis to data analysis, data management and interpretation of results. We are also listed in the RIsources Poral of the DFG (RI_00466).
Contact
Address
Analytics Core Facility Essen (ACE)
Universität Duisburg-Essen
ZMB
Universitätsstr. 2
45141 Essen
ACE Core Facility Manager
Dr. Farnusch Kaschani
office: S03 S02 A62
MS-Labs: T03 R-1 C11/C14/C18
office: +49201 183 4924
MS-Lab: +49201 183 6839
Publications
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Activity-Based Protein Profiling for the Identification of Novel Carbohydrate-Active Enzymes Involved in Xylan Degradation in the Hyperthermophilic Euryarchaeon Thermococcus sp. Strain 2319x1EIn: Frontiers in Microbiology Vol. 12 (2022)
ISSN: 1664-302XOnline Full Text: dx.doi.org/ Online Full Text (Open Access) -
Correction to : Natural brominated phenoxyphenols kill persistent and biofilm-incorporated cells of MRSA and other pathogenic bacteriaIn: Applied Microbiology and Biotechnology (2021) in press
ISSN: 1432-0614; 0175-7598; 0171-1741Online Full Text: dx.doi.org/ (Open Access) -
Targeted substrate loop insertion by VCP/p97 during PP1 complex disassemblyIn: Nature Structural & Molecular Biology Vol. 28 (2021) Nr. 12, pp. 964 - 971
ISSN: 1545-9993; 1545-9985Online Full Text: dx.doi.org/ -
Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasisIn: Cell Reports Vol. 37 (2021) Nr. 8,
ISSN: 2211-1247Online Full Text: dx.doi.org/ (Open Access) -
Article leaf apoplast of field-grown potato analyzed by quantitative proteomics and activity-based protein profilingIn: International Journal of Molecular Sciences (IJMS) Vol. 22 (2021) Nr. 21,
ISSN: 1422-0067; 1661-6596Online Full Text: dx.doi.org/ (Open Access) -
The chemical compound ‘Heatin’ stimulates hypocotyl elongation and interferes with the Arabidopsis NIT1-subfamily of nitrilasesIn: The Plant Journal Vol. 106 (2021) Nr. 6, pp. 1523 - 1540
ISSN: 1365-313X; 0960-7412Online Full Text: dx.doi.org/ (Open Access) -
Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances Vol. 10 (2020) Nr. 48, pp. 28711 - 28719
ISSN: 2046-2069Online Full Text: dx.doi.org/ (Open Access) -
Protein Phosphatase-1 Complex Disassembly by p97 is Initiated through Multivalent Recognition of Catalytic and Regulatory Subunits by the p97 SEP-domain AdaptersIn: Journal of Molecular Biology (JMB) Vol. 432 (2020) Nr. 23, pp. 6061 - 6074
ISSN: 1089-8638; 0022-2836Online Full Text: dx.doi.org/ -
Accelerated trypsin autolysis by affinity polymer templatesIn: RSC Advances Vol. 10 (2020) Nr. 48, pp. 28711 - 28719
ISSN: 2046-2069Online Full Text: dx.doi.org/ (Open Access) -
Discovering the RNA-binding proteome of plant leaves with an improved RNA interactome capture methodIn: Biomolecules Vol. 10 (2020) Nr. 4,
ISSN: 2218-273XOnline Full Text: dx.doi.org/ (Open Access) -
Natural brominated phenoxyphenols kill persistent and biofilm-incorporated cells of MRSA and other pathogenic bacteriaIn: Applied Microbiology and Biotechnology Vol. 104 (2020) Nr. 13, pp. 5985 - 5998
ISSN: 1432-0614; 0175-7598; 0171-1741; 0340-2118Online Full Text: dx.doi.org/ (Open Access) -
Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in actin polymerizationIn: Biological Chemistry Vol. 401 (2020) Nr. 8, pp. 955 - 968
ISSN: 1437-4315; 1431-6730Online Full Text: dx.doi.org/ (Open Access) -
Using proteomics for an insight into the performance of activated sludge in a lab-scale WWTPIn: International Biodeterioration & Biodegradation Vol. 149 (2020) pp. 104934
ISSN: 0964-8305Online Full Text: dx.doi.org/ -
Zelkovamycin is an OXPHOS Inhibitory Member of the Argyrin Natural Product FamilyIn: Chemistry: A European Journal Vol. 26 (2020) Nr. 39, pp. 8524 - 8531
ISSN: 1521-3765; 0947-6539Online Full Text: dx.doi.org/ (Open Access) -
Cathepsin L regulates metabolic networks controlling rapid cell growth and proliferationIn: Molecular and Cellular Proteomics Vol. 18 (2019) Nr. 7, pp. 1330 - 1344
ISSN: 1535-9476; 1535-9484Online Full Text: dx.doi.org/ (Open Access) -
Cathepsins Drive Anti-Inflammatory Activity by Regulating Autophagy and Mitochondrial Dynamics in Macrophage Foam CellsIn: Cellular Physiology and Biochemistry Vol. 53 (2019) Nr. 3, pp. 550 - 572
ISSN: 1015-8987; 1421-9778Online Full Text: dx.doi.org/ (Open Access) -
A homology-guided, genome-based proteome for improved proteomics in the alloploid Nicotiana benthamianaIn: BMC Genomics Vol. 20 (2019) Nr. 1, pp. 722
ISSN: 1471-2164Online Full Text: dx.doi.org/ (Open Access) -
Plant chemical genetics reveals colistin sulphate as a SA and NPR1-independent PR1 inducer functioning via a p38-like kinase pathwayIn: Scientific Reports Vol. 9 (2019) Nr. 1, pp. 11196
ISSN: 2045-2322Online Full Text: dx.doi.org/ (Open Access) -
Activity-based proteomics reveals nine target proteases for the recombinant protein-stabilizing inhibitor S/CYS8 in Nicotiana benthamianaIn: Plant Biotechnology Journal Vol. 17 (2019) Nr. 8, pp. 1670 - 1678
ISSN: 1467-7652; 1467-7644Online Full Text: dx.doi.org/ (Open Access) -
Dynamic hydrolase labelling as a marker for seed quality in Arabidopsis seedsIn: The Biochemical Journal Vol. 476 (2019) Nr. 5, pp. 843 - 857
ISSN: 1470-8728Online Full Text: dx.doi.org/ (Open Access) -
Proteases underground : Analysis of the maize root apoplast identifies organ specific papain-like cysteine protease activityIn: Frontiers in Plant Science Vol. 10 (2019)
ISSN: 1664-462XOnline Full Text: dx.doi.org/ (Open Access) -
Glycosidase and glycan polymorphism control hydrolytic release of immunogenic flagellin peptidesIn: Science Vol. 364 (2019) Nr. 6436, pp. eaav0748
ISSN: 1095-9203; 0036-8075Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Metabolic reconstruction of the genome of candidate Desulfatiglans TRIP_1 and identification of key candidate enzymes for anaerobic phenanthrene degradationIn: Environmental Microbiology Vol. 21 (2019) Nr. 4, pp. 1267 - 1286
ISSN: 1462-2912; 1462-2920Online Full Text: dx.doi.org/ (Open Access) -
Triazine probes target ascorbate peroxidases in plantsIn: Plant Physiology Vol. 180 (2019) Nr. 4, pp. 1848 - 1859
ISSN: 1532-2548; 0032-0889Online Full Text: dx.doi.org/ (Open Access)