ZMB Member Peter Bayer

ZMB Member
Peter Bayer

Next ZMB-Member
portrait photo of ZMB member Peter Bayer
© UDE/P.Bayer

Prof. Dr. Peter Bayer

Group

Structural and Medicinal Biochemistry

Faculty of Biology
University of Duisburg-Essen
Universitätsstr. 2
45141 Essen

Research Overview

The department Structural and Medicinal Biochemistry focuses on the elucidation of protein-protein and protein-ligand interactions using biochemical and biophysical strategies in addition to NMR as the main tool for the structure determination of biomolecules. Our research is geared towards predominantly human enzymes/proteins and their macromolecular complexes involved in posttranslational modification processes.

  1. Protein Structure Determination
  2. Biochemical Characterisation of Parvulins
  3. Biophysical studies on the interaction of synthetic supramolecular ligands and proteins
Read more

Selected Publications

    Journal articles

  • Neblik, Jonas; Kirupakaran, Abbna; Beuck, Christine; Mieres-Perez, Joel; Niemeyer, Felix; Le, My-Hue; Telgheder, Ursula; Schmuck, Jessica Felice; Dudziak, Alexander; Bayer, Peter; Sanchez-Garcia, Elsa; Westermann, Stefan; Schrader, Thomas
    Multivalent Molecular Tweezers Disrupt the Essential NDC80 Interaction with Microtubules
    In: Journal of the American Chemical Society: JACS Vol. 145 (2023) Nr. 28, pp. 15251 - 15264
    ISSN: 0002-7863; 1520-5126
    Online Full Text: dx.doi.org/
  • Blüggel, Mike; Kröning, Alexander; Kracht, Matthias; van den Boom, Johannes; Dabisch, Matthias; Göhring, Anna; Kaschani, Farnusch; Kaiser, Markus; Bayer, Peter; Meyer, Hemmo; Beuck, Christine
    The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPase
    In: Nature Communications Vol. 14 (2023) Nr. 1,
    ISSN: 2041-1723
    Online Full Text: dx.doi.org/ (Open Access)
  • Warmerdam, Zoey; Kamba, Bianca; Le, My-Hue; Schrader, Thomas; Isaacs, Lyle; Bayer, Peter; Hof, Fraser
    Binding Methylarginines and Methyllysines as Free Amino Acids : A Comparative Study of Multiple Host Classes
    In: ChemBioChem Vol. 23 (2022) Nr. 2,
    ISSN: 1439-4227; 1439-7633
    Online Full Text: dx.doi.org/ (Open Access)
  • Höing, Alexander; Struth, Robin; Beuck, Christine; Rafieiolhosseini, Neda; Hoffmann, Daniel; Stauber, Roland H.; Bayer, Peter; Niemeyer, Jochen; Knauer, Shirley
    Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligand
    In: RSC Advances Vol. 12 (2022) Nr. 53, pp. 34176 - 34184
    ISSN: 2046-2069
    Online Full Text: dx.doi.org/ (Open Access)
  • Höing, Alexander; Kirupakaran, Abbna; Beuck, Christine; Pörschke, Marius; Niemeyer, Felix; Seiler, Theresa; Hartmann, Laura; Bayer, Peter; Schrader, Thomas; Knauer, Shirley
    Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular Tweezers
    In: Biomacromolecules Vol. 23 (2022) Nr. 11, pp. 4504 - 4518
    ISSN: 1525-7797; 1526-4602
    Online Full Text: dx.doi.org/
  • Wetzel, Oliver; Prymak, Oleg; Loza, Kateryna; Gumbiowski, Nina; Heggen, Marc; Bayer, Peter; Beuck, Christine; Weidenthaler, Claudia; Epple, Matthias
    Water-Based Synthesis of Ultrasmall Nanoparticles of Platinum Group Metal Oxides (1.8 nm)
    In: Inorganic Chemistry Vol. 61 (2022) Nr. 12, pp. 5133 - 5147
    ISSN: 1520-510X; 0020-1669
    Online Full Text: dx.doi.org/
  • Wetzel, Oliver; Hosseini, Shabnam; Loza, Kateryna; Heggen, Marc; Prymak, Oleg; Bayer, Peter; Beuck, Christine; Schaller, Torsten; Niemeyer, Felix; Weidenthaler, Claudia; Epple, Matthias
    Metal-Ligand Interface and Internal Structure of Ultrasmall Silver Nanoparticles (2 nm)
    In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Vol. 125 (2021) Nr. 21, pp. 5645 - 5659
    ISSN: 1520-5207; 1089-5647
    Online Full Text: dx.doi.org/
  • van der Meer, Selina Beatrice; Hadrovic, Inesa; Meiners, Annika; Loza, Kateryna; Heggen, Marc; Knauer, Shirley; Bayer, Peter; Schrader, Thomas; Beuck, Christine; Epple, Matthias
    New tools to probe the protein surface : Ultrasmall gold nanoparticles carry amino acid binders
    In: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Vol. 125 (2021) Nr. 1, pp. 115 - 127
    ISSN: 1520-5207; 1520-6106; 1089-5647
    Online Full Text: dx.doi.org/ (Open Access)
  • Ruks, Tatjana; Loza, Kateryna; Heggen, Marc; Prymak, Oleg; Sehnem, Andre Luiz; Oliveira, Cristiano L. P.; Bayer, Peter; Beuck, Christine; Epple, Matthias
    Peptide-Conjugated Ultrasmall Gold Nanoparticles (2 nm) for Selective Protein Targeting
    In: ACS Applied Bio Materials Vol. 4 (2021) Nr. 1, pp. 945 - 965
    ISSN: 2576-6422
    Online Full Text: dx.doi.org/ (Open Access)
  • Meiners, Annika; Bäcker, Sandra; Hadrovic, Inesa; Heid, Christian; Beuck, Christine; Ruiz-Blanco, Yasser B.; Mieres-Perez, Joel; Pörschke, Marius; Grad, Jean-Noël; Vallet, Cecilia; Hoffmann, Daniel; Bayer, Peter; Sánchez-García, Elsa; Schrader, Thomas; Knauer, Shirley
    Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezers
    In: Nature Communications Vol. 12 (2021) Nr. 1, pp. 1505
    ISSN: 2041-1723
    Online Full Text: dx.doi.org/ (Open Access)
  • Ruks, Tatjana; Loza, Kateryna; Heggen, Marc; Ottmann, Christian; Bayer, Peter; Beuck, Christine; Epple, Matthias
    Targeting the Surface of the Protein 14-3-3 by Ultrasmall (1.5 nm) Gold Nanoparticles Carrying the Specific Peptide CRaf
    In: ChemBioChem Vol. 22 (2021) Nr. 8, pp. 1456 - 1463
    ISSN: 1439-4227; 1439-7633
    Online Full Text: dx.doi.org/ (Open Access)
  • Killinger, Kerstin; Böhm, Miriam; Steinbach, Philine; Hagemann, Götz; Blüggel, Mike; Jänen, Karolin; Hohoff, Simone; Bayer, Peter; Herzog, Franz; Westermann, Stefan
    Auto-inhibition of Mif2/CENP-C ensures centromere-dependent kinetochore assembly in budding yeast
    In: The EMBO Journal Vol. 39 (2020) Nr. 14, pp. e102938
    ISSN: 0261-4189; 1460-2075
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Vallet, Cecilia; Aschmann, Dennis; Beuck, Christine; Killa, Matthias; Meiners, Annika; Mertel, Marcel; Ehlers, Martin; Bayer, Peter; Schmuck, Carsten; Giese, Michael R. A.; Knauer, Shirley
    Functional Disruption of the Cancer-Relevant Interaction between Survivin and Histone H3 with a Guanidiniocarbonyl Pyrrole Ligand
    In: Angewandte Chemie International Edition Vol. 59 (2020) Nr. 14, pp. 5567 - 5571
    ISSN: 1521-3773; 1433-7851; 0570-0833
    Online Full Text: dx.doi.org/ (Open Access)
  • Bayer, Peter; Matena, Anja; Beuck, Christine
    NMR Spectroscopy of supramolecular chemistry on protein surfaces
    In: Beilstein Journal of Organic Chemistry Vol. 16 (2020) pp. 2505 - 2522
    ISSN: 1860-5397; 2195-951X
    Online Full Text: dx.doi.org/ (Open Access)
  • Göhring, Anna; Michin, Irina; Gerdes, Tina; Schulze, Nina; Blüggel, Mike; Rehic, Edisa; Kaschani, Farnusch; Kaiser, Markus; Bayer, Peter
    Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in actin polymerization
    In: Biological Chemistry Vol. 401 (2020) Nr. 8, pp. 955 - 968
    ISSN: 1437-4315; 1431-6730
    Online Full Text: dx.doi.org/ (Open Access)
  • van den Boom, Johannes; Hensel, Astrid; Trusch, Franziska; Matena, Anja; Siemer, Svenja; Guel, Désirée; Docter, Dominic; Höing, Alexander; Bayer, Peter; Stauber, Roland H.; Knauer, Shirley
    The other side of the corona : Nanoparticles inhibit the protease taspase1 in a size-dependent manner
    In: Nanoscale Vol. 12 (2020) Nr. 37, pp. 19093 - 19103
    ISSN: 2040-3372; 2040-3364
    Online Full Text: dx.doi.org/
  • Born, Alexandra; Nichols, Parker J.; Henen, Morkos A.; Chi, Celestine N.; Strotz, Dean; Bayer, Peter; Tate, Shin-Ichi; Peng, Jeffrey W.; Vögeli, Beat
    Backbone and side-chain chemical shift assignments of full-length, apo, human Pin1, a phosphoprotein regulator with interdomain allostery
    In: Biomolecular NMR Assignments Vol. 13 (2019) Nr. 1, pp. 85 - 89
    ISSN: 1874-270X; 1874-2718
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • van der Meer, Selina; Loza, Kateryna; Wey, Karolin; Heggen, Marc; Beuck, Christine; Bayer, Peter; Epple, Matthias
    Click chemistry on the surface of ultrasmall gold nanoparticles (2 nm) for covalent ligand attachment followed by nmr spectroscopy
    In: Langmuir Vol. 35 (2019) Nr. 22, pp. 7191 - 7204
    ISSN: 0743-7463; 1520-5827
    Online Full Text: dx.doi.org/
  • Bartsch, Lina; Bartel, Maria; Gigante, Alba; Iglesias-Fernández, Javier; Ruiz-Blanco, Yasser B.; Beuck, Christine; Briels, Jeroen; Tötsch, Niklas; Bayer, Peter; Sánchez-García, Elsa; Ottmann, Christian; Schmuck, Carsten
    Multivalent Ligands with Tailor-Made Anion Binding Motif as Stabilizers of Protein–Protein Interactions
    In: ChemBioChem Vol. 20 (2019) Nr. 23, pp. 2921 - 2926
    ISSN: 1439-4227; 1439-7633
    Online Full Text: dx.doi.org/
  • Ruks, Tatjana; Beuck, Christine; Schaller, Torsten; Niemeyer, Felix; Zähres, Manfred; Loza, Kateryna; Heggen, Marc; Hagemann, Ulrich; Mayer, Christian; Bayer, Peter; Epple, Matthias
    Solution NMR Spectroscopy with Isotope-Labeled Cysteine (¹³C and ¹⁵N) Reveals the Surface Structure of l -Cysteine-Coated Ultrasmall Gold Nanoparticles (1.8 nm)
    In: Langmuir Vol. 35 (2019) Nr. 3, pp. 767 - 778
    ISSN: 0743-7463; 1520-5827
    Online Full Text: dx.doi.org/
  • Rehic, Edisa; Hönig, Dana; Kamba, Bianca; Göhring, Anna; Hofmann, Eckhard; Gasper, Raphael; Matena, Anja; Bayer, Peter
    Structural Analysis of the 42 kDa Parvulin of Trypanosoma brucei
    In: Biomolecules Vol. 9 (2019) Nr. 3,
    ISSN: 2218-273X
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Blüggel, Mike; van den Boom, Johannes; Meyer, Hemmo; Bayer, Peter; Beuck, Christine
    Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPase
    In: Biomolecules Vol. 9 (2019) Nr. 12,
    ISSN: 2218-273X
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Trusch, Franziska; Loebach, Lars; Wawra, Stephan; Durward, Elaine; Wuensch, Andreas; Iberahim, Nurul Aqilah; De Bruijn, Irene; MacKenzie, Kevin; Willems, Ariane; Toloczko, Aleksandra; Diéguez-Uribeondo, Javier; Rasmussen, Tim; Schrader, Thomas; Bayer, Peter; Secombes, Chris J.; Van West, Pieter
    Cell entry of a host-targeting protein of oomycetes requires gp96
    In: Nature Communications Vol. 9 (2018) Nr. 1, pp. 2347
    ISSN: 2041-1723
    Online Full Text: dx.doi.org/ (Open Access)
  • Matena, Anja; Rehic, Edisa; Hönig, Dana; Kamba, Bianca; Bayer, Peter
    Structure and function of the human parvulins Pin1 and Par14/17
    In: Biological Chemistry Vol. 399 (2018) Nr. 2, pp. 101 - 125
    ISSN: 1437-4315; 1431-6730
    Online Full Text: dx.doi.org/ (Open Access)
  • Wawra, Stephan; Trusch, Franziska; Matena, Anja; Apostolakis, Kostis; Linne, Uwe; Zhukov, Igor; Stanek, Jan; Koźmiński, Wiktor; Davidson, Ian; Secombes, Chris J.; Bayer, Peter; van West, Pieter
    The RxLR motif of the host targeting effector AVR3a of phytophthora infestans is cleaved before secretion
    In: The Plant Cell Vol. 29 (2017) Nr. 6, pp. 1184 - 1195
    ISSN: 1532-298X; 1040-4651
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Hartmann-Fatu, Cristina; Bayer, Peter
    Determinants of tyrosylprotein sulfation coding and substrate specificity of tyrosylprotein sulfotransferases in metazoans
    In: Chemico-Biological Interactions Vol. 259 (2016) Nr. Part A, pp. 17 - 22
    ISSN: 0009-2797; 1872-7786
    Online Full Text: dx.doi.org/
  • Trusch, Franziska; Kowski, Klaus; Bravo-Rodriguez, Kenny; Beuck, Christine; Sowislok, Andrea; Wettig, Burkhard; Matena, Anja; Sánchez-García, Elsa; Meyer, Hemmo; Schrader, Thomas; Bayer, Peter
    Molecular tweezers target a protein-protein interface and thereby modulate complex formation
    In: Chemical Communications: ChemComm Vol. 52 (2016) Nr. 98, pp. 14141 - 14144
    ISSN: 1364-548X; 0009-241X; 0022-4936; 1359-7345
    Online Full Text: dx.doi.org/ (Open Access)
  • Hoppstock, Lukas; Trusch, Franziska; Lederer, Christoph; van West, Pieter; Koenneke, Martin; Bayer, Peter
    NmPin from the marine thaumarchaeote Nitrosopumilus maritimus is an active membrane associated prolyl isomerase
    In: BMC Biology (incorporating Journal of Biology) Vol. 14 (2016) Nr. 1, pp. 53
    ISSN: 1741-7007
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • van den Boom, Johannes; Trusch, Franziska; Hoppstock, Lukas; Beuck, Christine; Bayer, Peter
    Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1
    In: PLoS ONE Vol. 11 (2016) Nr. 3, pp. e0151431
    ISSN: 1932-6203
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Hartmann-Fatu, Cristina; Trusch, Franziska; Moll, Carina; Michin, Irina; Hassinen, Antti; Kellokumpu, Sakari; Bayer, Peter
    Heterodimers of Tyrosylprotein Sulfotransferases Suggest Existence of a Higher Organization Level of Transferases in the Membrane of the trans-Golgi Apparatus
    In: Journal of Molecular Biology (JMB) Vol. 427 (2015) Nr. Issue 6, Part B, pp. 1404 - 1412
    ISSN: 1089-8638; 0022-2836
    Online Full Text: dx.doi.org/
  • Saningong, Akuma D.; Bayer, Peter
    Human DNA-binding peptidyl-prolyl cis/trans isomerase Par14 is cell cycle dependently expressed and associates with chromatin in vivo
    In: BMC Biochemistry Vol. 16 (2015) Nr. 1,
    ISSN: 1471-2091
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Roy Choudhury, Amrita; Sikorska, Emilia; van den Boom, Johannes; Bayer, Peter; Popenda, Lukasz; Szutkowski, Kosma; Jurga, Stefan; Bonomi, Massimiliano; Sali, Andrej; Zhukov, Igor; Passamonti, Sabina; Novič, Marjana
    Structural model of the bilitranslocase transmembrane domain supported by NMR and FRET data
    In: PLoS ONE Vol. 10 (2015) Nr. 8, pp. e0135455
    ISSN: 1932-6203
    Online Full Text: dx.doi.org/ (Open Access)
  • Trusch, Franziska; Matena, Anja; Vuk, Maja; Körver, Lisa; Knævelsrud, Helene; Freemont, Paul S.; Meyer, Hemmo; Bayer, Peter
    The N-terminal region of the ubiquitin regulatory X (UBX) domain-containing protein 1 (UBXD1) modulates interdomain communication within the valosin-containing protein p97
    In: The Journal of Biological Chemistry (JBC) Vol. 290 (2015) Nr. 49, pp. 29414 - 29427
    ISSN: 0021-9258; 1083-351X
    Online Full Text: dx.doi.org/ (Open Access)
  • van den Boom, Johannes; Mamic, Marija; Baccelliere, Daniele; Zweerink, Susanne; Kaschani, Farnusch; Knauer, Shirley; Bayer, Peter; Kaiser, Markus
    Peptidyl succinimidyl peptides as taspase 1 inhibitors
    In: ChemBioChem Vol. 15 (2014) Nr. 15, pp. 2233 - 2237
    ISSN: 1439-4227; 1439-7633
    Online Full Text: dx.doi.org/
  • Grum, Daniel; Franke, Stefan; Kraff, Oliver; Heider, Dominik; Schramm, Alexander; Hoffmann, Daniel; Bayer, Peter
    Design of a Modular Protein-Based MRI Contrast Agent for Targeted Application
    In: PLoS ONE Vol. 8 (2013) Nr. 6, pp. e65346
    ISSN: 1932-6203
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Elfaki, Imadeldin; Knitsch, Andre; Matena, Anja; Bayer, Peter
    Identification and characterization of peptides that bind the PPIase domain of Parvulin17
    In: Journal of Peptide Science Vol. 19 (2013) Nr. 6, pp. 362 - 369
    ISSN: 1075-2617; 1099-1387
    Online Full Text: dx.doi.org/
  • Matena, Anja; Sinnen, Christian; van den Boom, Johannes; Wilms, Christoph; Dybowski, Jan Nikolaj; Maltaner, Ricarda; Müller, Jonathan W.; Link, Nina M.; Hoffmann, Daniel; Bayer, Peter
    Transient domain interactions enhance the affinity of the mitotic regulator pin1 toward phosphorylated peptide ligands
    In: Structure Vol. 21 (2013) Nr. 10, pp. 1769 - 1777
    ISSN: 1878-4186
    Online Full Text: dx.doi.org/ (Open Access)
  • Schröder, Elisabeth; Gebel, Lena; Eremeev, Andrey A.; Morgner, Jessica; Grum, Daniel; Knauer, Shirley; Bayer, Peter; Müller, Jonathan W.
    Document Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasm
    In: PLoS ONE Vol. 7 (2012) Nr. 1, pp. e29559
    ISSN: 1932-6203
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Wawra, Stephan; Bain, Judith; Durward, Elaine; De Bruijn, Irene; Minor, Kirsty L.; Matena, Anja; Löbach, Lars; Whisson, Stephen C.; Bayer, Peter; Porter, Andrew J.; Birch, Paul R. J.; Secombes, Chris J.; Van West, Pieter
    Host-targeting protein 1 (SpHtp1) from the oomycete Saprolegnia parasitica translocates specifically into fish cells in a tyrosine-O-sulphate-dependent manner
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 109 (2012) Nr. 6, pp. 2096 - 2101
    ISSN: 1091-6490; 0027-8424
    Online Full Text: dx.doi.org/
  • Hoeppner, Astrid; Thomas, Frank; Rueppel, Alma; Hensel, Reinhard; Blankenfeldt, Wulf; Bayer, Peter; Faust, Annette
    Structure of the corrinoid : coenzyme M methyltransferase MtaA from Methanosarcina mazei
    In: Acta Crystallographica Section D: Biological Crystallography Vol. 68 (2012) Nr. 11, pp. 1549 - 1557
    ISSN: 0907-4449; 1399-0047
    Online Full Text: dx.doi.org/
  • Elfaki, Imadeldin; Bayer, Peter; Müller, Jonathan W.
    A potential transcriptional regulator is out-of-frame translated from the metallothionein 2A messenger RNA
    In: Analytical Biochemistry Vol. 409 (2011) Nr. 1, pp. 159 - 161
    ISSN: 0003-2697; 1096-0309
    Online Full Text: dx.doi.org/
  • Müller, Jonathan W.; Link, Nina C; Matena, Anja; Hoppstock, Lukas; Rüppel, Alma; Bayer, Peter; Blankenfeldt, Wulf
    Crystallographic Proof for an Extended Hydrogen Bonding Network in Small Prolyl Isomerases
    In: Journal of the American Chemical Society: JACS Vol. 133 (2011) Nr. 50, pp. 20096 - 20099
    ISSN: 0002-7863; 1520-5126
    Online Full Text: dx.doi.org/ Online Full Text
  • Lederer, Christoph; Heider, Dominik; van den Boom, Johannes; Hoffmann, Daniel; Müller, Jonathan W.; Bayer, Peter
    Single-Domain Parvulins Constitute a Specific Marker for Recently Proposed Deep-Branching Archaeal Subgroups
    In: Evolutionary Bioinformatics Vol. 7 (2011) pp. 135 - 148
    ISSN: 1176-9343
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Jaremko, Lukasz; Jaremko, Mariusz; Elfaki, Imadeldin; Müller, Jonathan W.; Ejchart, Andrzej; Bayer, Peter; Zhukov, Igor
    Structure and Dynamics of the First Archaeal Parvulin Reveal a New Functionally Important Loop in Parvulin-type Prolyl Isomerases
    In: The Journal of Biological Chemistry (JBC) Vol. 286 (2011) pp. 6554 - 6565
    ISSN: 0021-9258; 1083-351X
    Online Full Text: dx.doi.org/ (Open Access)
  • Link, Nina M.; Hunke, Cornelia; Müller, Jonathan W.; Eichler, Jutta; Bayer, Peter
    The solution structure of pGolemi, a high affinity Mena EVH1 binding miniature protein, suggests explanations for paralog-specific binding to Ena/VASP homology (EVH) 1 domains
    In: Biological Chemistry Vol. 390 (2009) Nr. 5-6, pp. 417 - 426
    ISSN: 1437-4315
    Online Full Text: dx.doi.org/
  • Müller, Jonathan W.; Bayer, Peter
    Small family with key contacts : par14 and par17 parvulin proteins, relatives of pin1, now emerge in biomedical research
    In: Perspectives in Medicinal Chemistry Vol. 2 (2008) pp. 11 - 20
    ISSN: 1177-391X
    Online Full Text: dx.doi.org/ (Open Access)
  • Zhukov, Igor; Bayer, Peter; Schölermann, Beate; Ejchart, Andrzej
    15N magnetic relaxation study of backbone dynamics of the ribosomeassociated cold shock response protein Yfia of Escherichia coli
    In: Acta Biochimica Polonica Vol. 54 (2007) Nr. 4, pp. 769 - 775
    ISSN: 1734-154X; 0001-527X
    (Open Access)
  • Kessler, Daniel; Papatheodorou, Panagiotis; Stratmann, Tina; Dian, Elke Andrea; Hartmann-Fatu, Cristina; Rassow, Joachim; Bayer, Peter; Müller, Jonathan W.
    The DNA binding parvulin Par17 is targeted to the mitochondrial matrix by a recently evolved prepeptide uniquely present in Hominidae.
    In: BMC Biology (incorporating Journal of Biology) Vol. 5 (2007) pp. 37
    ISSN: 1741-7007
    Online Full Text: dx.doi.org/
  • Mueller, J.W.; Kessler, D.; Neumann, D.; Stratmann, T.; Papatheodorou, P.; Hartmann-Fatu, C.; Bayer, Peter
    Characterization of novel elongated Parvulin isoforms that are ubiquitously expressed in human tissues and originate from alternative transcription initiation.
    In: BMC Molecular Biology Vol. 7 (2006) pp. 9
    ISSN: 1471-2199
  • Harjes, E.; Harjes, S.; Wohlgemuth, S.; Mueller, K.H.; Krieger, E.; Herrmann, C.; Bayer, Peter
    GTP-Ras disrupts the intramolecular complex of C1 and RA domains of Nore1.
    In: Structure Vol. 14 (2006) pp. 881 - 888
  • Goettsch, Sandra; Badea, Rodica A.; Müller, Jonathan W.; Wotzlaw, Christoph; Schoelermann, Beate; Schulz, Lars; Rabiller, Matthias; Bayer, Peter; Hartmann-Fatu, Cristina
    Human TPST1 Transmembrane Domain Triggers Enzyme Dimerisation and Localisation to the Golgi Compartment
    In: Journal of Molecular Biology (JMB) Vol. 361 (2006) Nr. 3, pp. 436 - 449
    ISSN: 1089-8638; 0022-2836
    Online Full Text: dx.doi.org/
  • Niculae, A.; Gruen, M.; Bayer, Peter; Breitling, R.; Alexandrov, K.
    Isotopic labelling of recombinant proteins expressed in the protozoan host Leishmania tarentolae.
    In: Protein Expression & Purification Vol. 48 (2006) pp. 167 - 172
  • Hecker, Christina-Maria; Rabiller, Matthias; Haglund, Kaisa; Bayer, Peter; Dikic, Ivan
    Specification of SUMO1- and SUMO2-interacting motifs
    In: The Journal of Biological Chemistry (JBC) Vol. 281 (2006) Nr. 23, pp. 16117 - 16127
    ISSN: 0021-9258; 1083-351X
    Online Full Text: dx.doi.org/ (Open Access)
  • Bayer, E.; Thutewohl, M.; Christner, C.; Waldmann, H.; Bayer, Peter
    Identification of hPin1 inhibitors that induce apoptosis in a mammalian Ras transformed cell line
    In: Chemical Communications: ChemComm Vol. 4 (2005) pp. 516 - 518
    ISSN: 1364-548X; 0009-241X; 0022-4936; 1359-7345
    Online Full Text: dx.doi.org/
  • Harjes, Stefan; Bayer, Peter; Scheidig, Axel J.
    The crystal structure of human PAPS synthetase 1 reveals asymmetry in substrate binding
    In: Journal of Molecular Biology (JMB) Vol. 347 (2005) Nr. 3, pp. 623 - 635
    ISSN: 1089-8638; 0022-2836
    Online Full Text: dx.doi.org/
  • Harjes, Stefan; Scheidig, Axel; Bayer, Peter
    Expression, purification and crystallization of human 3′- phosphoadenosine-5′-phosphosulfate synthetase 1
    In: Acta Crystallographica Section D: Structural Biology Vol. 60 (2004) Nr. 2, pp. 350 - 352
    ISSN: 0907-4449
    Online Full Text: dx.doi.org/
  • Blankenfeldt, Wulf; Kuzin, Alexandre P.; Skarina, Tatiana; Korniyenko, Yuriy; Tong, Liang; Bayer, Peter; Janning, Petra; Thomashow, Linda S.; Mavrodi, Dmitri V.
    Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens
    In: Proceedings of the National Academy of Sciences of the United States of America Vol. 101 (2004) Nr. 47, pp. 16431 - 16436
    ISSN: 0027-8424
    Online Full Text: dx.doi.org/ (Open Access)
  • Reimer, Tatiana; Weiwad, Matthias; Schierhorn, Angelika; Ruecknagel, Peter-Karl; Rahfeld, Jens-Ulrich; Bayer, Peter; Fischer, Gunter
    Phosphorylation of the N-terminal domain regulates subcellular localization and DNA binding properties of the peptidyl-prolyl cis/trans isomerase hPar14
    In: Journal of Molecular Biology (JMB) Vol. 330 (2003) Nr. 5, pp. 955 - 966
    ISSN: 1089-8638; 0022-2836
    Online Full Text: dx.doi.org/
  • Bayer, Elena; Goettsch, Sandra; Müller, Jonathan W.; Griewel, Bernhard; Guiberman, Elena; Mayr, Lorenz M.; Bayer, Peter
    Structural analysis of the mitotic regulator hPin1 in solution : insights into domain architecture and substrate binding
    In: The Journal of Biological Chemistry (JBC) Vol. 278 (2003) Nr. 28, pp. 26183 - 26193
    ISSN: 0021-9258; 1083-351X
    Online Full Text: dx.doi.org/ (Open Access)
  • Goettsch, S.; Goettsch, W.; Morawietz, H.; Bayer, Peter
    Induction of tyrosylprotein sulfotransferase isoform shift in human endothelial cells
    In: Circulation Vol. 106 (2002) Nr. Suppl. 2, pp. 287
    ISSN: 1524-4539; 0009-7322; 0065-8499
  • Kalinin, Alexander; Rak, Alexej; Shcherbakov, Dmitry; Bayer, Peter
    Letter to the Editor: ¹H, ¹³C and ¹⁵N resonance assignments of the ribosome-associated cold shock response protein Yfia of Escherichia coli
    In: Journal of Biomolecular NMR Vol. 23 (2002) Nr. 4, pp. 335 - 336
    ISSN: 0925-2738
    Online Full Text: dx.doi.org/
  • Goettsch, Sandra; Goettsch, Winfried; Morawietz, Henning; Bayer, Peter
    Shear stress mediates tyrosylprotein sulfotransferase isoform shift in human endothelial cells
    In: Biochemical and Biophysical Research Communications (BBRC) Vol. 294 (2002) Nr. 3, pp. 541 - 546
    ISSN: 0006-291X
    Online Full Text: dx.doi.org/
  • Rak, Alexey; Kalinin, Alexander; Shcherbakov, Dmitry; Bayer, Peter
    Solution structure of the ribosome-associated cold shock response protein Yfia of Escherichia coli
    In: Biochemical and Biophysical Research Communications (BBRC) Vol. 299 (2002) Nr. 5, pp. 710 - 714
    ISSN: 0006-291X
    Online Full Text: dx.doi.org/
  • Goettsch, S.; Bayer, Peter
    Structural attributes in the conjugation of Ubiquitin, RUB and SUMO to protein substrates.
    In: Frontiers in Bioscience Vol. 7 (2002) pp. 148 - 162
  • Surmacz, Tatiana Anna; Bayer, Elena; Rahfeld, Jens-Ulrich; Fischer, Gunter; Bayer, Peter
    The N-terminal basic domain of human parvulin h Par14 is responsible for the entry to the nucleus and high-affinity DNA-binding
    In: Journal of Molecular Biology (JMB) Vol. 321 (2002) Nr. 2, pp. 235 - 247
    ISSN: 1089-8638; 0022-2836
    Online Full Text: dx.doi.org/
  • Kipping, M.; Zarnt, T.; Kiessig, S.; Reimer, U.; Fischer, G.; Bayer, Peter
    Increased backbone flexibility in threonine
    In: Biochemistry Vol. 40 (2001) Nr. 27, pp. 7957 - 7963
    ISSN: 1520-4995; 0006-2960
    Online Full Text: dx.doi.org/
  • Kohlbacher, Oliver; Burchardt, Andreas; Moll, Andreas; Hildebrandt, Andreas; Bayer, Peter; Lenhof, Hans-Peter
    Structure prediction of protein complexes by an NMR-based protein docking algorithm
    In: Journal of Biomolecular NMR Vol. 20 (2001) Nr. 1, pp. 15 - 21
    ISSN: 0925-2738
    Online Full Text: dx.doi.org/
  • Sekerina, E; Rahfeld, J U; Müller, J; Fanghänel, J; Rascher, C; Fischer, G; Bayer, Peter
    NMR solution structure of hPar14 reveals similarity to the peptidyl prolyl cis/trans isomerase domain of the mitotic regulator hPin1 but indicates a different functionality of the protein
    In: Journal of Molecular Biology (JMB) Vol. 301 (2000) Nr. 4, pp. 1003 - 1017
    ISSN: 1089-8638; 0022-2836
    Online Full Text: dx.doi.org/
  • Bayer, Peter; Varani, Luca; Varani, Gabriele
    Nuclear magnetic resonance methods to study RNA-protein complexes
    In: Methods in Enzymology Vol. 317: RNA - Ligand Interactions, Part A (2000) pp. 198 - 220
    ISSN: 1557-7988; 0076-6879
    Online Full Text: dx.doi.org/
  • Marx, Ute Charlotte; Adermann, Knut; Bayer, Peter; Forssmann, Wolf-Georg; Rösch, Paul
    Solution structures of human parathyroid hormone fragments hPTH(1-34) and hPTH(1-39) and bovine parathyroid hormone fragment bPTH(1-37)
    In: Biochemical and Biophysical Research Communications (BBRC) Vol. 267 (2000) Nr. 1, pp. 213 - 220
    ISSN: 0006-291X
    Online Full Text: dx.doi.org/
Read more