There were 1160 publications found

• Kracht, Matthias; Kröning, Alexander; van den Boom, Johannes; Gahlot, Pinki; Koska, Sandra; Kiss, Leo; Meyer, Hemmo

  The accessory adapters FAF1, FAF2, and UBXN7 accelerate proteasomal degradation by increasing prior p97-mediated substrate unfolding

  In: Science Advances, Vol. 12, 2026, Nr. 10, eaea7381

  DOI (Open Access)
• Esposito-Verza, Arianna; Conti, Duccio; Rodrigues Pedroso, Paulo D.; Oberste-Lehn, Lina; Koerner, Carolin; Wohlgemuth, Sabine; Mansurkhodzhaev, Artem; Vetter, Ingrid R.; Pesenti, Marion E.; Musacchio, Andrea

  Molecular requirements for PLK1 activation by T-loop phosphorylation

  In: The EMBO Journal, Vol. 45, 2026, Nr. 5, pp. 1496 – 1536

  DOI (Open Access)
• Liu, Mei; Wei, You; Weber, Lisa-Marie; Mladenov, Emil; Lin, Xixi; Mladenova, Veronika; Shafaat, Ramtin Omid; Pantelias, Gabriel E.; Gkika, Eleni; Stuschke, Martin; Soni, Aashish; Iliakis, George

  Condensins regulate resection-dependent DNA double-strand break repair pathways in replicated chromatin

  In: Nucleic Acids Research, Vol. 54, 2026, Nr. 4, gkag076

  DOI (Open Access)
• Peng, JuanFei; Yang, JiaJin; Antonopoulou, Georgia; Fang, Rui; Adhikari, Bikash; Vogt, Markus; Wolf, Elmar; Sun, Chong; Du, Shangce; Godfrey, Laura; Gupta, Aayush; Trajkovic-Arsic, Marija; Teichmann, Nicole; Grünwald, Barbara T.; Krebs, Niklas; Steiger, Katja; Mogler, Carolin; Althoff, Kristina; Wang, Xin; Giglio, Giovanni; Liffers, Sven-Thorsten; Savvatakis, Konstantinos; Braren, Rickmer; Lawlor, Rita T.; Scarpa, Aldo; Behrens, Diana; Lang, Karl S.; Cheung, Phyllis F.; Siveke, Jens T.

  Combined targeted and epigenetic-based therapy enhances antitumor immunity by stabilizing GATA6-dependent MHCI expression in pancreatic ductal adenocarcinoma

  In: Nature Communications, Vol. 17, 2026, Nr. 1, 1476

  DOI (Open Access)
• Li, Xin; Lebeaupin, Cynthia; Kadianaki, Aikaterini; Druelle-Cedano, Clementine; Vesper, Niklas; Rennert, Charlotte; Huguet-Pradell, Júlia; Gomez Ramos, Borja; Fan, Chaofan; Piecyk, Robert Stefan; Zizmare, Laimdota; Ramadori, Pierluigi; Li, Luqing; Frick, Lukas; Qiu, Menjie; Zhang, Cangang; Martins Nascentes Melo, Luiza; Ranvir, Vikas Prakash; Shen, Peng; Hanselmann, Johannes; Kosla, Jan; Fernández-Vaquero, Mirian; Vucur, Mihael; Baskaran, Praveen; Bao, Xuanwen; Coleman, Olivia I.; Tang, Yingyue; Cetin, Miray; Chen, Zhouji; Jang, Insook; Del Prete, Stefania; Rahbari, Mohammad; Zhang, Peng; Pham, Timothy V.; Hou, Yushan; Sun, Aihua; Gu, Li; Kim, Laura C.; Rothermel, Ulrike; Heide, Danijela; Ali, Adnan; Gallage, Suchira; Talvard-Balland, Nana; Piqué-Gili, Marta; Gris-Oliver, Albert; Bevilacqua, Alessio; Schlicker, Lisa; Duffey, Alec; Unger, Kristian; Szydlowska, Marta; Hetzer, Jenny; Odom, Duncan T.; Machauer, Tim; Bucci, Daniele; Sant, Pooja; Lee, Jun-Hoe; Rösler, Jonas; Meckelmann, Sven; Schreck, Johannes; Murray, Sue; Simon, M. Celeste; Nahnsen, Sven; Schulze, Almut; Ho, Ping-Chih; Jugold, Manfred; Breuhahn, Kai; Mallm, Jan-Philipp; Schirmacher, Peter; Roth, Susanne; Rahbari, Nuh; Tschaharganeh, Darjus F.; Roessler, Stephanie; Goeppert, Benjamin; Bengsch, Bertram; Andrieux, Geoffroy; Boerries, Melanie; Malek, Nisar P.; Prinz, Marco; Weber, Achim; Zeiser, Robert; Tamayo, Pablo; Bronsert, Peter; Kurowski, Konrad; Thimme, Robert; Yuan, Detian; Carretero, Rafael; Luedde, Tom; Pinyol, Roser; Hartmann, Felix J.; Karin, Michael; Tasdogan, Alpaslan; Trautwein, Christoph; Mall, Moritz; Hofmann, Maike; Llovet, Josep M.; Haller, Dirk; Kaufman, Randal J.; Heikenwälder, Mathias

  Activated ATF6α is a hepatic tumour driver restricting immunosurveillance

  In: Nature, 2026, in press

  DOI (Open Access)
• Kremer, Nora; Mueller, Franziska; Nguyen, Hang; Schulz, Louisa; Popp, Tanja; Artes, Elena; Wolters, Julian; Renner, Michael; Vetter, Ingrid; Maffini, Stefano; Robles, Maria S.; Musacchio, Andrea; Bange, Tanja

  CUL4A-DDB1-DCAF10 is an N-recognin for N-terminally acetylated Src kinases

  In: Nature Communications, Vol. 17, 2026, Nr. 1, 132

  DOI (Open Access)
• Zhang, Ruirui; Liu, Jie; Gasper, Raphael; Unger, Anke; Kaschani, Farnusch; Kaiser, Markus; Janning, Petra; Waldmann, Herbert

  Covalent modification of a glutamic acid inspired by HaloTag technology

  In: Nature Communications, Vol. 17, 2026, Nr. 1, 1257

  DOI (Open Access)
• Bolli, Evangelia; Wirapati, Pratyaksha; Hicham, Mehdi; Xie, Yuxuan; Siwicki, Marie; Duval, Florent; Goubet, Anne-Gaëlle; Kiss, Máté; Zitti, Béatrice; Zwahlen, Thomas; Mcdowell, Sheri; Bill, Ruben; Angerani, Simona; Engblom, Camilla; Anderson, Seth; Jiang, Aiping; Hartley, Oliver; Sykes, David B.; Jankovic, Maja; Fournier, Nadine; Gunzer, Matthias; Tarussio, David; Tissot, Stéphanie; Sadow, Peter M.; Faquin, William C.; Sade-Feldman, Moshe; Weissleder, Ralph; Pai, Sara; Mercier, François; Manguso, Robert; Pittet, Mikaël J.

  CCL3 is produced by aged neutrophils across cancers and promotes tumor growth

  In: Cancer Cell, 2026, in press

  DOI (Open Access)
• Anker, Markus S.; Anker, Stefan D.; Rassaf, Tienush

  The EMPATICC-trial : should location shape therapy?

  In: European Heart Journal, 2026, in press

  DOI
• Walstein, Kai; Hill, Louisa; Vogt, Doro; Oberste-Lehn, Lina; Janning, Petra; Vetter, Ingrid R; Pan, Dongqing; Musacchio, Andrea

  M18BP1 valency and a distributed interaction footprint determine epigenetic centromere specification in humans

  In: The EMBO Journal, 2026, in press

  DOI (Open Access)
• Brenner, Joel Cyrille; Zirden, Linda; Almeida-Hernandez, Yasser; Kaschani, Farnusch; Kaiser, Markus; Sanchez-Garcia, Elsa; Poepsel, Simon; Hellerschmied-Jelinek, Doris

  Conformational plasticity of a BiP-GRP94 chaperone complex

  In: Nature Structural & Molecular Biology, Vol. 32, 2025, Nr. 10, pp. 1947 – 1958

  DOI (Open Access)
• Klein, Lukas; Tu, Mengyu; Krebs, Niklas; Urbach, Laura; Grimm, Daniela; Latif, Muhammad Umair; Penz, Frederike; Blandau, Anna; Wu, Xueyan; Samuel, Rebecca Diya; Küffer, Stefan; Wegwitz, Florian; Chan, Nathan; Aliar, Kazeera; Vyas, Foram; Kishore, Uday; Hessmann, Elisabeth; Trumpp, Andreas; Espinet, Elisa; Papantonis, Argyris; Khokha, Rama; Ellenrieder, Volker; Grünwald, Barbara; Singh, Shiv K.

  Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response in pancreatic cancer

  In: Nature Communications, Vol. 16, 2025, Nr. 1, 335

  DOI (Open Access)
• Knox, Jennifer J.; Jang, Gun Ho; Grant, Robert C.; Zhang, Amy; Ma, Lucy; Elimova, Elena; Jang, Raymond; Moore, Malcolm; Biagi, James; Tehfe, Mustapha; Ramjeesingh, Ravi; Tsang, Erica S.; Holter, Spring; Ramotar, Stephanie; Hutchinson, Shawn; Liang, Sheng-Ben; Lungu, Ilinca M.; Moura, Shari; Wang, Yifan; Perera, Sheron; Chan-Seng-Yue, Michelle; Monajemzadeh, Maryam; Aung, Kyaw; Prince, Rebecca; Romero, Joan Miguel; Fuentes-Antras, Jesus; Gonzalez Conchas, Galileo A.; Picardo, Sarah; Gonzalez, Ricardo; Ghai, Sangeet; Khalili, Korosh; Kyoung Kim, Tae; Ng, Karen; Bartlett, John; Pugh, Trevor J.; Kalimuthu, Sangeetha N.; Fischer, Sandra E.; Wilson, Julie M.; Dodd, Anna; Zogopoulos, George; Grünwald, Barbara T.; Notta, Faiyaz; Gallinger, Steven; O’Kane, Grainne M.

  Whole genome and transcriptome profiling in advanced pancreatic cancer patients on the COMPASS trial

  In: Nature Communications, Vol. 16, 2025, Nr. 1, 5919

  DOI (Open Access)
• Rausch, Tobias; Schäfer, Hendrik; Bein, Julia; Mölder, Felix; Beeck, Lilian Kara; Kölsch, Bernd; Borchert, Sabrina; Benes, Vladimir; Halbsguth, Teresa; Brunnberg, Uta; Oellerich, Thomas; Tousseyn, Thomas; Ponzoni, Maurilio; Köster, Johannes; Hansmann, Martin-Leo; Küppers, Ralf; Hartmann, Sylvia

  Genetic lesions in nodular lymphocyte-predominant Hodgkin lymphoma and T cell/histiocyte-rich large B-cell lymphoma identified by whole genome sequencing

  In: Leukemia, Vol. 39, 2025, Nr. 9, pp. 2215 – 2225

  DOI (Open Access)
• Pabst, Kim M; Weber, Manuel; Laschinsky, Christina; Sandach, Patrick; Bartel, Timo; Küper, Alina T; Kessler, Lukas; Trajkovic-Arsic, Marija; Eckstein, Markus; Gilman, Elena; Nader, Michael; Barbato, Francesco; Podleska, Lars; Hadaschik, Boris; Hamacher, Rainer; Kersting, David; von Ostau, Nicola; von Tresckow, Bastian; Kaelberlah, Hans-Peter; Kesch, Claudia; Kuemmel, Sherko; Reinacher-Schick, Anke; Schuler, Martin; Siveke, Jens; Grünwald, Viktor; Herrmann, Ken; Fendler, Wolfgang P.

  [⁶⁸Ga]Ga-FAPI-46 PET accuracy for cancer imaging with histopathology validation : A single-centre, single-arm, interventional, phase 2 trial

  In: The Lancet Oncology, Vol. 26, 2025, Nr. 9, pp. 1204 – 1214

  DOI (Open Access)
• Kähler, K.C.; Hassel, J.C.; Ziemer, M.; Rutkowski, P.; Meier, F.; Flatz, L.; Gaudy-Marqueste, C.; Zimmer, Lisa; Santinami, M.; Russano, F.; von Wasielewski, I.; Eigentler, T.K.; Maio, M.; Zalaudek, I.; Haferkamp, S.; Quaglino, P.; Welzel, J.; Röcken, C.; Enk, A.; Simon, J.-C.; Świtaj, T.; Garzarolli, M.; Amaral, T.; Malissen, N.; Livingstone, Elisabeth; Elia, G.; Covelli, A.; Lorizzo, K.; Neri, D.; Mulatto, S.; Parca, A.; Pizzichi, B.; Ascierto, P.A.; Garbe, C.; Robert, C.; Schadendorf, Dirk; Hauschild, A.

  Neoadjuvant intralesional targeted immunocytokines (daromun) in stage III melanoma

  In: Annals of Oncology, Vol. 36, 2025, Nr. 10, pp. 1166 – 1177

  DOI (Open Access)
• Pylaeva, Ekaterina; Tollrian, Lea; Riedesel, Jana; Shevchuk, Olga; Thiel, Ilona; Ozel, Irem; Kabankova, Nastassia; Voß, Hannah; Siebels, Bente; Schlüter, Hartmut; Haist, Corinna; Hanenberg, Helmut; Mattheis, Stefan; Kürten, Cornelius; Sperandio, Markus; Kehrmann, Jan; Engel, Daniel Robert; Lang, Stephan; Jablonska, Jadwiga

  G-CSF/NAMPT signaling drives neutrophil dysfunction and enhances bacterial infection susceptibility in cancer patients

  In: Nature Communications, Vol. 16, 2025, Nr. 1, 11137

  DOI (Open Access)
• Giuranna, Johanna; Zheng, Yiran; Brandt, Matthäus; Jall, Sigrid; Mukherjee, Amrita; Shankhwar, Soni; Renner, Simone; Kurapati, Nirup Kumar; May, Caroline; Peters, Triinu; Herpertz-Dahlmann, Beate; Seitz, Jochen; de Zwaan, Martina; Herzog, Wolfgang; Ehrlich, Stefan; Zipfel, Stephan; Giel, Katrin; Egberts, Karin; Burghardt, Roland; Föcker, Manuel; Marcus, Katrin; Keyvani, Kathy; Müller, Timo D.; Schmitz, Frank; Rajcsanyi, Luisa Sophie; Hinney, Anke

  Genetic and functional analyses of CTBP2 in anorexia nervosa and body weight regulation

  In: Molecular Psychiatry, Vol. 30, 2025, Nr. 5, pp. 1836 – 1846

  DOI (Open Access)
• Schwarz, Tatjana; Ptok, Johannes; Damagnez, Maximilian; Menne, Christopher; Alizei, Elahe Salimi; Lang-Meli, Julia; Maas, Michelle; Habermann, Daniel; Hoffmann, Daniel; Schulze zur Wiesch, Julian; Lauer, Georg; Kefalakes, Helenie; Cornberg, Markus; Kraft, Anke RM.; Gliga, Smaranda; Bock, Hans H.; Horn, Peter A.; Maini, Mala K.; Thimme, Robert; Wedemeyer, Heiner; Nattermann, Jacob; Heinemann, Falko M.; Luedde, Tom; Neumann-Haefelin, Christoph; Walker, Andreas; Timm, Jörg

  HBV shows different levels of adaptation to HLA class I-associated selection pressure correlating with markers of replication

  In: Journal of Hepatology, Vol. 82, 2025, Nr. 5, pp. 805 – 815

  DOI (Open Access)
• Schmiedtchen, Marco; Maisuls, Iván; Siera, Hannah; Balszuweit, Jan; Wölper, Christoph; Giese, Michael R. A.; Haberhauer, Gebhard; Strassert, Cristian A.; Voskuhl, Jens

  In situ Cyclization of Aromatic Thioethers in Emissive Materials to Generate Phosphorescent Dibenzothiophenes

  In: Angewandte Chemie International Edition, Vol. 64, 2025, Nr. 2, e202414326

  DOI (Open Access)
• Maassen, Fabienne; Le-Trilling, Vu Thuy Khanh; Betke, Luisa; Bracht, Thilo; Siegmund, Corinna; Bayer, Malte; Katschinski, Benjamin; Belter, Antonia; Becker, Tanja; Mennerich, Denise; Voigt, Sebastian; Frappier, Lori; Sitek, Barbara; Fleischhauer, Katharina; Trilling, Mirko

  The human cytomegalovirus-encoded pUS28 antagonizes CD4+ T cell recognition by targeting CIITA

  In: eLife, Vol. 14, 2025, e96414

  DOI, Online Full Text (Open Access)
• Ronnacker, Julian; Müller, Philippe J.; Mikesch, Jan-Henrik; Zukunft, Sven; Weinbergerová, Barbora; Šrámek, Jiří; Valka, Jan; Novak, Jan; Zak, Pavel; Szotkowski, Tomas; Koristek, Zdenek; Krekeler, Carolin; Unglaub, Julia M.; Sauer, Tim; Ruhnke, Leo; Kraus, Sabrina; Schaffrath, Judith; Müller, Lutz P.; Kaes, Sabrina; Niemann, Dirk; Fransecky, Lars; Hess, Patrick P.; Crysandt, Martina; Jost, Edgar; Millo, Joana; Gaertner, Johannes; Repp, Roland; Jentzsch, Madlen; Hoppe, Lea; Klein, Stefan; Modemann, Franziska; Michalowski, Nina; Fischbach, Klaudia; Blau, Wolfgang; Ruhs, Marion; Ritter, Markus; Lohmeyer, Julian; Steffen, Björn; Hauser, Sarah; Kaufmann, Martin; Krause, Stefan W.; Knabe, Ricarda; Spiekermann, Karsten; Serve, Hubert; Platzbecker, Uwe; Baldus, Claudia D.; Müller-Tidow, Carsten; Lenz, Georg; Reinhardt, Christian; Mayer, Jirí; Bornhäuser, Martin; Röllig, Christoph; Schliemann, Christoph; Hanoun, Maher

  Gemtuzumab ozogamicin in first-line treatment of CBF-AML : Insights from a retrospective multi-center analysis

  In: Leukemia, Vol. 39, 2025, Nr. 9, pp. 2174 – 2180

  DOI (Open Access)
• Usama, Muhammad; Razzaq, Samad; Hättig, Christof; Steinmann, Stephan N.; Exner, Kai S.

  Oxygen evolution reaction on IrO₂(110) is governed by Walden-type mechanisms

  In: Nature Communications, Vol. 16, 2025, Nr. 1, 6137

  DOI (Open Access)
• Rodier, Clement; Estabrook, Ian D.; Chan, Eunice HoYee; Rice, Gavin; Loreau, Vincent; Raunser, Stefan; Görlich, Dirk; Friedrich, Benjamin M.; Schnorrer, Frank

  Muscle growth by sarcomere divisions

  In: Science Advances, Vol. 11, 2025, Nr. 28, eadw9445

  DOI (Open Access)
• Kim, Jinjong; Usama, Muhammad; Exner, Kai; Joo, Sang Hoon

  Renaissance of Chlorine Evolution Reaction : Emerging Theory and Catalytic Materials

  In: Angewandte Chemie International Edition, Vol. 64, 2025, Nr. 1, e202417293

  DOI (Open Access)
• Ng’ang’a, Peter Njenga; Folz, Julian; Kucher, Svetlana; Roderer, Daniel; Xu, Ying; Sitsel, Oleg; Belyy, Alexander; Prumbaum, Daniel; Kühnemuth, Ralf; Assafa, Tufa E.; Dong, Min; Seidel, Claus A.M.; Bordignon, Enrica; Raunser, Stefan

  Multistate kinetics of the syringe-like injection mechanism of Tc toxins

  In: Science Advances, Vol. 11, 2025, Nr. 1, eadr2019

  DOI (Open Access)
• Reinders, Maike; Kravic, Bojana; Gahlot, Pinki; Koska, Sandra; van den Boom, Johannes; Schulze, Nina; Levantovsky, Sophie; Kleine, Stefan; Kaiser, Markus; Kulathu, Yogesh; Behrends, Christian; Meyer, Hemmo

  ATXN3 regulates lysosome regeneration after damage by targeting K48-K63-branched ubiquitin chains

  In: The EMBO Journal, Vol. 44, 2025, Nr. 18, pp. 5086 – 5111

  DOI (Open Access)
• Wu, Tong; Dhaka, Kapil; Luo, Mengjia; Wang, Bingqing; Wang, Meng; Xi, Shibo; Zhang, Mingsheng; Huang, Fuqiang; Exner, Kai S.; Lum, Yanwei

  CCooperative Active Sites on Ag2Pt3TiS6 for Enhanced Low-Temperature Ammonia Fuel Cell Electrocatalysis

  In: Angewandte Chemie International Edition, Vol. 64, 2025, Nr. 6, e202418691 , in press

  DOI (Open Access)
• Lopez, Juanita; Powles, Thomas; Braiteh, Fadi; Siu, Lillian L.; LoRusso, Patricia; Friedman, Claire F.; Balmanoukian, Ani S.; Gordon, Michael; Yachnin, Jeffrey; Rottey, Sylvie; Karydis, Ioannis; Fisher, George A.; Schmidt, Marcus; Schuler, Martin; Sullivan, Ryan J.; Burris, Howard A.; Galvao, Vladimir; Henick, Brian S.; Dirix, Luc; Jaeger, Dirk; Ott, Patrick A.; Wong, Kit Man; Jerusalem, Guy; Schiza, Aglaia; Fong, Lawrence; Steeghs, Neeltje; Leidner, Rom S.; Rittmeyer, Achim; Laurie, Scott A.; Gort, Eelke; Aljumaily, Raid; Melero, Ignacio; Sabado, Rachel L.; Rhee, Ina; Mancuso, Michael R.; Muller, Lars; Fine, Gregg D.; Yadav, Mahesh; Kim, Leesun; Leveque, Vincent J. P.; Robert, Alberto; Darwish, Martine; Qi, Ting; Zhu, Jiawen; Zhang, Jingbin; Twomey, Patrick; Rao, Gautham K.; Low, Donald W.; Petry, Chris; Lo, Amy A.; Schartner, Jill M.; Delamarre, Lélia; Mellman, Ira; Löwer, Martin; Müller, Felicitas; Derhovanessian, Evelyna; Cortini, Andrea; Manning, Luisa; Maurus, Daniel; Brachtendorf, Sebastian; Lörks, Verena; Omokoko, Tana; Godehardt, Eva; Becker, Dirk; Hawner, Christine; Wallrapp, Christine; Albrecht, Christian; Kröner, Christoph; Tadmor, Arbel D.; Diekmann, Jan; Vormehr, Mathias; Jork, Anette; Paruzynski, Anna; Lang, Maren; Blake, Jonathon; Hennig, Oliver; Kuhn, Andreas N.; Sahin, Ugur; Türeci, Özlem; Camidge, D. Ross

  Autogene cevumeran with or without atezolizumab in advanced solid tumors: a phase 1 trial

  In: Nature Medicine, Vol. 31, 2025, Nr. 1, pp. 152 – 164

  DOI (Open Access)
• Doglioni, Ginevra; Fernández-García, Juan; Igelmann, Sebastian; Altea-Manzano, Patricia; Blomme, Arnaud; La Rovere, Rita; Liu, Xiao-Zheng; Liu, Yawen; Tricot, Tine; Nobis, Max; An, Ning; Leclercq, Marine; El Kharraz, Sarah; Karras, Panagiotis; Hsieh, Yu-Heng; Solari, Fiorella A.; Martins Nascentes Melo, Luiza; Allies, Gabrielle; Scopelliti, Annalisa; Rossi, Matteo; Vermeire, Ines; Broekaert, Dorien; Ferreira Campos, Ana Margarida; Neven, Patrick; Maetens, Marion; Van Baelen, Karen; Alkan, H. Furkan; Planque, Mélanie; Floris, Giuseppe; Sickmann, Albert; Tasdogan, Alpaslan; Marine, Jean-Christophe; Scheele, Colinda L. G. J.; Desmedt, Christine; Bultynck, Geert; Close, Pierre; Fendt, Sarah-Maria

  Aspartate signalling drives lung metastasis via alternative translation

  In: Nature, Vol. 638, 2025, Nr. 2, pp. 244 – 250

  DOI, Online Full Text (Open Access)
• Spangenberg, Philippa; Bessler, Sebastian; Widera, Lars; Bottek, Jenny; Richter, Mathis; Thiebes, Stephanie; Siemes, Devon; Krauß, Sascha D.; Migas, Lukasz G.; Kasarla, Siva Swapna; Phapale, Prasad; Kleesiek, Jens; Führer, Dagmar; Möller, Lars; Heuer, Heike; Van de Plas, Raf; Gunzer, Matthias; Soehnlein, Oliver; Soltwisch, Jens; Shevchuk, Olga; Dreisewerd, Klaus; Engel, Daniel R.

  msiFlow : automated workflows for reproducible and scalable multimodal mass spectrometry imaging and microscopy data analysis

  In: Nature Communications, Vol. 16, 2025, Nr. 1, 1065

  DOI (Open Access)
• Salguero-Linares, Jose; Armengot, Laia; Ayet, Joel; Ruiz-Solaní, Nerea; Saile, Svenja C; Salas-Gómez, Marta; Fernandez, Esperanza; Denolf, Lode; Navarrete, Fernando; Krumbach, Jenna; Kaiser, Markus; Stael, Simon; Van Breusegem, Frank; Gevaert, Kris; Kaschani, Farnusch; Petersen, Morten; El Kasmi, Farid; Valls, Marc; Coll, Núria S

  Lack of AtMC1 catalytic activity triggers autoimmunity dependent on NLR stability

  In: EMBO Reports, Vol. 26, 2025, Nr. 9, pp. 2378 – 2412

  DOI (Open Access)
• Amaral, T.; Ottaviano, M.; Arance, A.; Blank, C.; Chiarion-Sileni, V.; Donia, M.; Dummer, R.; Garbe, C.; Gershenwald, J.E.; Gogas, H.; Guckenberger, M.; Haanen, J.; Hamid, O.; Hauschild, A.; Höller, C.; Lebbé, C.; Lee, R.J.; Long, G.V.; Lorigan, P.; Muñoz Couselo, E.; Nathan, P.; Robert, C.; Romano, E.; Schadendorf, Dirk; Sondak, V.; Suijkerbuijk, K.P.M.; van Akkooi, A.C.J.; Michelin, O.; Ascierto, P.A.; Michielin, O.

  Cutaneous melanoma : ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

  In: Annals of Oncology, Vol. 36, 2025, Nr. 1, pp. 10 – 30

  DOI
• Zhao, Ben; Fang, Rui; Schürmann, Hendrik; Hemmer, Erik Jan; Mayer, Gina Lauren; Trajkovic-Arsic, Marija; Althoff, Kristina; Yang, Jiajin; Godfrey, Laura; Liffers, Sven T.; Savvatakis, Konstantinos; Dorsch, Madeleine; Grüner, Barbara M.; Hahn, Stephan; Remke, Marc; Lueong, Smiths S.; Siveke, Jens T.

  PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma

  In: Cell Reports, Vol. 44, 2025, Nr. 4, 115541

  DOI (Open Access)
• Berg, Victoria; Lollies, Anna; Schneider, Markus; Johansson, Patricia; Weniger, Marc A.; Albertini, Emma; Facchetti, Fabio; Ascani, Stefano; Moawia, Abubakar; Bens, Susanne; Fischer, Anja; Siebert, Reiner; Klapper, Wolfram; Lorenzi, Luisa; Tiacci, Enrico; Hartmann, Sylvia; Budeus, Bettina; Hansmann, Martin-Leo; Küppers, Ralf

  Common origin and somatic mutation patterns of composite lymphomas and leukemias

  In: Leukemia, Vol. 39, 2025, Nr. 8, pp. 1960 – 1971

  DOI (Open Access)
• Melo, Luiza Martins Nascentes; Sabatier, Marie; Ramesh, Vijayashree; Szylo, Krystina J.; Fraser, Cameron S.; Pon, Alex; Mitchell, Evann C.; Servage, Kelly A.; Allies, Gabriele; Westedt, Isa V.; Cansiz, Feyza; Krystkiewicz, Jonathan; Kutritz, Andrea; Schadendorf, Dirk; Morrison, Sean J.; Ubellacker, Jessalyn M.; Sreelatha, Anju; Tasdogan, Alpaslan

  Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity

  In: Cancer Research, Vol. 85, 2025, Nr. 5, pp. 942 – 955

  DOI (Open Access)
• Kolb, Antonia; Kulis-Mandic, Ana-Marija; Klein, Matthias; Stastny, Anna; Haist, Maximilian; Votteler, Vanessa; Weidenthaler-Barth, Beate; Sinnberg, Tobias; Sucker, Antje; Allies, Gabriele; Albrecht, Jessica Lea; Tasdogan, Alpaslan; Tuettenberg, Andrea; Gaida, Matthias M.; Deppermann, Carsten; Stege, Henner; Schadendorf, Dirk; Grabbe, Stephan; Schulze-Osthoff, Klaus; Kramer, Daniela

  Constitutive expression of the transcriptional co-activator IκBζ promotes melanoma growth and immunotherapy resistance

  In: Nature Communications, Vol. 16, 2025, Nr. 1, 5387

  DOI (Open Access)
• Cmentowski, Verena; Musacchio, Andrea

  The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona

  In: Science Advances, Vol. 11, 2025, Nr. 37, eady6890

  DOI (Open Access)
• Führer, Siska; Gallant, Kai; Kaschani, Farnusch; Kaiser, Markus; Janning, Petra; Waldmann, Herbert; Gersch, Malte

  Small Molecule-Induced Alterations of Protein Polyubiquitination Revealed by Mass-Spectrometric Ubiquitome Analysis

  In: Angewandte Chemie International Edition, Vol. 64, 2025, Nr. 32, e202508916

  DOI (Open Access)
• Zeymer, Uwe; Freund, Anne; Noc, Marko; Akin, Ibrahim; Huber, Kurt; Pöss, Janine; Schneider, Steffen; Rassaf, Tienush; Jung, Christian; Tigges, Eike; Ouarrak, Taoufik; Desch, Steffen; Thiele, Holger

  Influence of Resuscitated Cardiac Arrest on Efficacy and Safety of Extracorporeal Life Support in Infarct-Related Cardiogenic Shock : A Substudy of the ECLS-SHOCK Trial

  In: Circulation, Vol. 151, 2025, Nr. 24, pp. 1752 – 1754

  DOI
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  Acid sphingomyelinase activity suggests a new antipsychotic pharmaco-treatment strategy for schizophrenia

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  Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity

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  Common hereditary variants of the APOE gene and posttransplant outcome in acute myeloid leukemia

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  Attenuated growth factor signaling during cell death initiation sensitizes membranes towards peroxidation

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  Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity

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  Immune training enhances anti-viral responses and improves outcomes in Pax5−/⁺ mice susceptible to chronic infection

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  A mouse model of cardiac immunoglobulin light chain amyloidosis reveals insights into tissue accumulation and toxicity of amyloid fibrils

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  Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors

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  Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma

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  Nitro-oleic acid enhances mitochondrial metabolism and ameliorates heart failure with preserved ejection fraction in mice

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