Selected Publications

ZMB Publications
Selected Publications

The list provides selected publications of the ZMB from 2004 to 2020, published in the journals listed below.

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(View all ZMB publications via the interface of the university bibliography).

Journals

  • ACS Nano
  • Acta Neuropathologica
  • Advanced Drug Delivery Reviews
  • All Nature Journals
  • American Journal of Human Genetics
  • Angewandte Chemie International Edition
  • Annals of Oncology
  • Annual Review of Biochemistry
  • Annual Review of Genetics
  • Annual Review of Microbiology
  • Biomaterials
  • Biotechnology Advances
  • Blood
  • Brain
  • Cancer Cell
  • Cancer Discovery
  • Cancer Research
  • Cell Clinical Cancer Research
  • Chemical Reviews
  • Chemical Society Reviews
  • Circulation
  • Circulation Research
  • EMBO Molecular Medicine
  • EMBO Reports
  • Endocrine Reviews
  • European Heart Journal
  • FEMS Microbiology Reviews
  • Gastroenterology
  • Gut
  • Immunity
  • Immunological Reviews
  • JAMA: Journal of the American Medical Association
  • JAMA Oncology
  • JAMA Neurology
  • Journal of Hepatology
  • Journal of the American Chemical Society
  • Journal of the American Medical Association
  • Journal of Clinical Oncology
  • Journal of Hepatology
  • Lancet
  • Leukemia
  • Molecular Cell
  • Molecular Psychiatry
  • Natural Product Research
  • Nature
  • Nature Biotechnology
  • Nature Chemical Biology
  • Nature Communications
  • Nature Genetics
  • Nature Medicine
  • Nature Methods
  • Nature Nanotechnology
  • Nature Reviews Molecular Cell Biology
  • Nature Reviews Neurology
  • Nature Structural & Molecular Biology
  • Neuro-Oncology
  • Nucleic Acids Research
  • Proceedings of the National Academy of Sciences of the United States of America Science
  • Science
  • Science Advances
  • The British Journal of Cancer
  • The EMBO Journal
  • The Lancet
  • The Lancet Diabetes and Endocrinology
  • The Lancet Infectious Diseases
  • The Lancet Oncology
  • The New England Journal of Medicine
  • Trends in Pharmacological Sciences
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There were 882 publications found

  • Lee, Jung-Hoon; Bollschweiler, Daniel; Schäfer, Tillman; Huber, Robert
    Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies
    In: Science Advances Vol. 7 (2021) Nr. 2, pp. eabd4413
    ISSN: 2375-2548
    Online Full Text: dx.doi.org/ (Open Access)
  • Obermann, Mark; Nägel, Steffen; Ose, Claudia; Sonuc, Nilüfer; Scherag, Andre; Storch, Peter; Gaul, Charly; Böger, Andreas; Kraya, Torsten; Jansen, Jan-Peter; Straube, Andreas; Freilinger, Tobias; Kaube, Holger; Jürgens, Tim P; Diener, Hans Christoph; Katsarava, Zaza; Kleinschnitz, Christoph; Holle, Dagny
    Safety and efficacy of prednisone versus placebo in short-term prevention of episodic cluster headache : A multicentre, double-blind, randomised controlled trial
    In: The Lancet Neurology Vol. 20 (2021) Nr. 1, pp. 29 - 37
    ISSN: 1474-4465; 1474-4422
    Online Full Text: dx.doi.org/
  • Schuler, Martin
    Corrigendum to “Inhibiting fibroblast growth factor receptors in cancer – The next generation”
    In: Annals of Oncology Vol. 32 (2021) Nr. 1, pp. 126
    ISSN: 1569-8041; 0923-7534
    Online Full Text: dx.doi.org/ (Open Access)
  • Schleier, Lena; Wiendl, Maximilian; Heidbreder, Karin; Binder, Marie-Theres; Atreya, Raja; Rath, Timo; Becker, Emily; Schulz-Kuhnt, Anja; Stahl, Annette; Schulze, Lisa Lou; Ullrich, Karen; Merz, Simon F.; Bornemann, Lea; Gunzer, Matthias; Watson, Alastair J.M.; Neufert, Clemens; Atreya, Imke; Neurath, Markus F.; Zundler, Sebastian
    Non-classical monocyte homing to the gut via α4β7 integrin mediates macrophage-dependent intestinal wound healing
    In: Gut Vol. 69 (2020) pp. 252 - 263
    ISSN: 1468-3288; 0017-5749
    Online Full Text: dx.doi.org/
  • Zhuang, Yuan; Xu, Haifeng C.; Shinde, Prashant V.; Warfsmann, Jens; Vasilevska, Jelena; Sundaram, Balamurugan; Behnke, Kristina; Huang, Jun; Hoell, Jessica I.; Borkhardt, Arndt; Pfeffer, Klaus; Taha, Mohamed S.; Herebian, Diran; Mayatepek, Ertan; Brenner, Dirk; Ahmadian, Mohammad Reza; Keitel, Verena; Wieczorek, Dagmar; Häussinger, Dieter; Pandyra, Aleksandra A.; Lang, Karl S.; Lang, Philipp A.
    Fragile X mental retardation protein protects against tumour necrosis factor-mediated cell death and liver injury
    In: Gut Vol. 69 (2020) Nr. 1, pp. 133 - 145
    ISSN: 1468-3288; 0017-5749
    Online Full Text: dx.doi.org/ (Open Access)
  • Köcher, Steffen; Resch, Sarah; Kessenbrock, Till; Schrapp, Lukas; Ehrmann, Michael; Kaiser, Markus
    From dolastatin 13 to cyanopeptolins, micropeptins, and lyngbyastatins : the chemical biology of Ahp-cyclodepsipeptides
    In: Natural Product Reports Vol. 37 (2020) Nr. 2, pp. 163 - 174
    ISSN: 0265-0568; 1460-4752
    Online Full Text: dx.doi.org/
  • Langer, Judith; Jimenez De Aberasturi, Dorleta; Aizpurua, Javier; Alvarez-Puebla, Ramon A.; Auguié, Baptiste; Baumberg, Jeremy J.; Bazan, Guillermo C.; Bell, Steven E. J.; Boisen, Anja; Brolo, Alexandre G.; Choo, Jaebum; Cialla-May, Dana; Deckert, Volker; Fabris, Laura; Faulds, Karen; García De Abajo, F. Javier; Goodacre, Royston; Graham, Duncan; Haes, Amanda J.; Haynes, Christy L.; Huck, Christian; Itoh, Tamitake; Käll, Mikael; Kneipp, Janina; Kotov, Nicholas A.; Kuang, Hua; Le Ru, Eric C.; Lee, Hiang Kwee; Li, Jian-Feng; Ling, Xing Yi; Maier, Stefan A.; Mayerhöfer, Thomas; Moskovits, Martin; Murakoshi, Kei; Nam, Jwa-Min; Nie, Shuming; Ozaki, Yukihiro; Pastoriza-Santos, Isabel; Perez-Juste, Jorge; Popp, Juergen; Pucci, Annemarie; Reich, Stephanie; Ren, Bin; Schatz, George C.; Shegai, Timur; Schlücker, Sebastian; Tay, Li-Lin; Thomas, K. George; Tian, Zhong-Qun; Van Duyne, Richard P.; Vo-Dinh, Tuan; Wang, Yue; Willets, Katherine A.; Xu, Chuanlai; Xu, Hongxing; Xu, Yikai; Yamamoto, Yuko S.; Zhao, Bing; Liz-Marzán, Luis M.
    Present and Future of Surface-Enhanced Raman Scattering
    In: ACS Nano Vol. 14 (2020) Nr. 1, pp. 28 - 117
    ISSN: 1936-086X; 1936-0851
    Online Full Text: dx.doi.org/ (Open Access)
  • Tasdogan, Alpaslan; Faubert, Brandon; Ramesh, Vijayashree; Ubellacker, Jessalyn M.; Shen, Bo; Solmonson, Ashley; Murphy, Malea M.; Gu, Zhimin; Gu, Wen; Martin, Misty; Kasitinon, Stacy Y.; Vandergriff, Travis; Mathews, Thomas P.; Zhao, Zhiyu; Schadendorf, Dirk; DeBerardinis, Ralph J.; Morrison, Sean J.
    Metabolic heterogeneity confers differences in melanoma metastatic potential
    In: Nature Vol. 577 (2020) Nr. 7788, pp. 115 - 120
    ISSN: 1476-4687; 0028-0836
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Heichler, Christina; Scheibe, Kristina; Schmied, Anabel; Geppert, Carol I; Schmid, Benjamin; Wirtz, Stefan; Thoma, Oana-Maria; Kramer, Viktoria; Waldner, Maximilian J; Büttner, Christian; Farin, Henner; Pešić, Marina; Knieling, Ferdinand; Merkel, Susanne; Grüneboom, Anika; Gunzer, Matthias; Grützmann, Robert; Rose-John, Stefan; Koralov, Sergei; Kollias, George; Vieth, Michael; Hartmann, Arndt; Greten, Florian; Neurath, Markus F; Neufert, Clemens
    STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis
    In: Gut Vol. 69 (2020) Nr. 7, pp. 1269 - 1282
    ISSN: 0017-5749
    Online Full Text: dx.doi.org/
  • Ugurel, Selma; Schadendorf, Dirk; Horny, K.; Sucker, Antje; Schramm, Sabine; Utikal, Jochen; Pföhler, Claudia; Herbst, Rudolf A.; Schilling, B.; Blank, Christian U.; Becker, Jürgen; Paschen, Annette; Zimmer, Lisa; Livingstone, Elisabeth; Horn, Peter; Rebmann, Vera
    Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanoma
    In: Annals of Oncology Vol. 31 (2020) Nr. 1, pp. 144 - 152
    ISSN: 1569-8041; 0923-7534
    Online Full Text: dx.doi.org/
  • Pfaff, Elke; Aichmüller, Christian; Sill, Martin; Stichel, Damian; Snuderl, Matija; Karajannis, Matthias A.; Schuhmann, Martin U.; Schittenhelm, Jens; Hasselblatt, Martin; Thomas, Christian; Korshunov, Andrey; Rhizova, Marina; Wittmann, Andrea; Kaufhold, Anna; Iskar, Murat; Ketteler, Petra; Lohmann, Dietmar; Orr, Brent A.; Ellison, David W.; von Hoff, Katja; Mynarek, Martin; Rutkowski, Stefan; Sahm, Felix; von Deimling, Andreas; Lichter, Peter; Kool, Marcel; Zapatka, Marc; Pfister, Stefan M.; Jones, David T. W.
    Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations
    In: Acta Neuropathologica Vol. 139 (2020) Nr. 2, pp. 243 - 257
    ISSN: 1432-0533; 0001-6322
    Online Full Text: dx.doi.org/
  • Pairault, Noël; Zhu, Hui; Jansen, Dennis; Huber, Alexander; Daniliuc, Constantin G.; Grimme, Stefan; Niemeyer, Jochen
    Heterobifunctional Rotaxanes for Asymmetric Catalysis
    In: Angewandte Chemie International Edition Vol. 59 (2020) Nr. 13, pp. 5102 - 5107
    ISSN: 1521-3773; 1433-7851; 0570-0833
    Online Full Text: dx.doi.org/ (Open Access)
  • Mladenov, Emil; Staudt, Christian; Soni, Aashish; Murmann-Konda, Tamara; Siemann-Loekes, Maria; Iliakis, George
    Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52
    In: Nucleic Acids Research Vol. 48 (2020) Nr. 4, pp. 1905 - 1924
    ISSN: 1362-4962; 0305-1048
    Online Full Text: dx.doi.org/ (Open Access)
  • Melms, Johannes C.; Vallabhaneni, Sreeram; Mills, Caitlin E.; Yapp, Clarence; Chen, Jia-Yun; Morelli, Eugenio; Waszyk, Patricia; Kumar, Sushil; Deming, Derrick; Moret, Nienke; Rodriguez, Steven; Subramanian, Kartik; Rogava, Meri; Cartwright, Adam N.R.; Luoma, Adrienne; Mei, Shaolin; Brinker, Titus J.; Miller, David M.; Spektor, Alexander; Schadendorf, Dirk; Riggi, Nicolo; Wucherpfennig, Kai W.; Sorger, Peter K.; Izar, Benjamin
    Inhibition of haspin kinase promotes cell-intrinsic and extrinsic antitumor activity
    In: Cancer Research Vol. 80 (2020) Nr. 4, pp. 798 - 810
    ISSN: 1538-7445; 0008-5472
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Migden, Michael R.; Khushalani, Nikhil I.; Chang, Anne Lynn S.; Lewis, Karl D.; Schmults, Chrysalyne D.; Hernandez-Aya, Leonel; Meier, Friedegund; Schadendorf, Dirk; Guminski, Alexander; Hauschild, Axel; Wong, Deborah J.; Daniels, Gregory A.; Berking, Carola; Jankovic, Vladimir; Stankevich, Elizabeth; Booth, Jocelyn; Li, Siyu; Weinreich, David M.; Yancopoulos, George D.; Lowy, Israel; Fury, Matthew G.; Rischin, Danny
    Cemiplimab in locally advanced cutaneous squamous cell carcinoma : results from an open-label, phase 2, single-arm trial
    In: The Lancet Oncology Vol. 21 (2020) Nr. 2, pp. 294 - 305
    ISSN: 1474-5488; 1470-2045
    Online Full Text: dx.doi.org/
  • Ascierto, P.A.; Lewis, K.D.; Di Giacomo, A.M.; Demidov, L.; Mandalà, M.; Bondarenko, I.; Herbert, C.; Mackiewicz, A.; Rutkowski, P.; Guminski, A.; Simmons, B.; Ye, C.; Hooper, G.; Wongchenko, M.J.; Goodman, G.R.; Yan, Y.; Schadendorf, Dirk
    Prognostic impact of baseline tumour immune infiltrate on disease-free survival in patients with completely resected, BRAFv⁶⁰⁰ mutation–positive melanoma receiving adjuvant vemurafenib
    In: Annals of Oncology Vol. 31 (2020) Nr. 1, pp. 153 - 159
    ISSN: 1569-8041; 0923-7534
    Online Full Text: dx.doi.org/
  • Hartkopf, Andreas; Nusch, Arnd; Decker, Thomas; Reinisch, Mattea; Heinrich, Bernhard J; Kurbacher, Christian; Fuchs, Roswitha; Tesch, Hans; Krabisch, Petra; Brucker, Sara; Fehm, Tanja N; Janni, Wolfgang; Kümmel, Sherko; Lüftner, Diana; Schneeweiss, Andreas; Schuler, Martin; Voges, Claudia; Schubert, Jörg; Fasching, Peter A
    RIBECCA - A phase IIIb, multi-center, open label study for women with estrogen receptor positive locally advanced or metastatic breast cancer treated with ribociclib (LEE011) in combination with letrozole : Results of the third interim analysis
    In: Cancer Research Vol. 80 (2020) Nr. 4,
    ISSN: 1538-7445; 0008-5472
    Online Full Text: dx.doi.org/
  • Siemer, Svenja; Westmeier, Dana; Barz, Matthias; Eckrich, Jonas; Wünsch, Désirée; Seckert, Christof; Thyssen, Christian; Schilling, Oliver; Hasenberg, Mike; Pang, Chengfang; Docter, Dominic; Knauer, Shirley K.; Stauber, Roland H.; Strieth, Sebastian
    Corrigendum to “Biomolecule-corona formation confers resistance of bacteria to nanoparticle-induced killing: Implications for the design of improved nanoantibiotics” [Biomaterials 192 (2019) 551–559]
    In: Biomaterials Vol. 263 (2020) pp. 120371
    ISSN: 1878-5905; 0142-9612
    Online Full Text: dx.doi.org/
  • Capdevila, Jaume; Wirth, Lori J.; Ernst, Thomas; Ponce Aix, Santiago; Lin, Chia-Chi; Ramlau, Rodryg; Butler, Marcus O.; Delord, Jean-Pierre; Gelderblom, Hans; Ascierto, Paolo A.; Fasolo, Angelica; Führer, Dagmar; Hütter-Krönke, Marie Luise; Forde, Patrick M.; Wrona, Anna; Santoro, Armando; Sadow, Peter M.; Szpakowski, Sebastian; Wu, Hongqian; Bostel, Geraldine; Faris, Jason; Cameron, Scott; Varga, Andreea; Taylor, Matthew
    PD-1 Blockade in Anaplastic Thyroid Carcinoma
    In: Journal of Clinical Oncology Vol. 38 (2020) Nr. 23, pp. 2620 - 2627
    ISSN: 1527-7755
    Online Full Text: dx.doi.org/ (Open Access)
  • Bengoa-Vergniory, Nora; Faggiani, Emilie; Ramos-Gonzalez, Paula; Kirkiz, Ecem; Connor-Robson, Natalie; Brown, Liam V.; Siddique, Ibrar; Li, Zizheng; Vingill, Siv; Cioroch, Milena; Cavaliere, Fabio; Threlfell, Sarah; Roberts, Bradley; Schrader, Thomas; Klärner, Frank-Gerrit; Cragg, Stephanie; Dehay, Benjamin; Bitan, Gal; Matute, Carlos; Bezard, Erwan; Wade-Martins, Richard
    CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease
    In: Nature Communications Vol. 11 (2020) Nr. 1, pp. 4885
    ISSN: 2041-1723
    Online Full Text: dx.doi.org/ (Open Access)
  • Cabrita, Rita; Lauss, Martin; Sanna, Adriana; Donia, Marco; Larsen, Mathilde; Schadendorf, Dirk
    Tertiary lymphoid structures improve immunotherapy and survival in melanoma
    In: Nature Vol. 577 (2020) Nr. 7791, pp. 561 - 565
    ISSN: 0028-0836; 1476-4687
    Online Full Text: dx.doi.org/
  • Garbe, Claus; Keim, Ulrike; Suciu, Stefan; Amaral, Teresa; Eigentler, Thomas K.; Gesierich, Anja; Hauschild, Axel; Heinzerling, Lucie; Kiecker, Felix; Schadendorf, Dirk; Stadler, Rudolf; Sunderkötter, Cord; Tüting, Thomas; Utikal, Jochen; Wollina, Uwe; Zouboulis, Christos C.; Keilholz, Ulrich; Testori, Alessandro; Martus, Peter; Leiter, Ulrike; Eggermont, Alexander M.M.
    Prognosis of patients with stage III melanoma according to American joint committee on cancer version 8 : A reassessment on the basis of 3 independent stage III melanoma cohorts
    In: Journal of Clinical Oncology Vol. 38 (2020) Nr. 22, pp. 2543 - 2551
    ISSN: 1527-7755; 0732-183X
    Online Full Text: dx.doi.org/ (Open Access)
  • Hagenacker, Tim; Wurster, Claudia D.; Günther, René; Schreiber-Katz, Olivia; Osmanovic, Alma; Petri, Susanne; Weiler, Markus; Ziegler, Andreas; Kuttler, Josua; Koch, Jan C.; Schneider, Ilka; Wunderlich, Gilbert; Schloss, Natalie; Lehmann, Helmar C.; Cordts, Isabell; Deschauer, Marcus; Lingor, Paul; Kamm, Christoph; Stolte, Benjamin; Pietruck, Lena; Totzeck, Andreas; Kizina, Kathrin; Mönninghoff, Christoph; von Velsen, Otgonzul; Ose, Claudia; Reichmann, Heinz; Forsting, Michael; Pechmann, Astrid; Kirschner, Janbernd; Ludolph, Albert C.; Hermann, Andreas; Kleinschnitz, Christoph
    Nusinersen in adults with 5q spinal muscular atrophy : A non-interventional, multicentre, observational cohort study
    In: The Lancet Neurology Vol. 19 (2020) Nr. 4, pp. 317 - 325
    ISSN: 1474-4465; 1474-4422
    Online Full Text: dx.doi.org/
  • Heinrich, Michael C.; Jones, Robin L.; von Mehren, Margaret; Schöffski, Patrick; Serrano, César; Kang, Yoon-Koo; Cassier, Philippe A.; Mir, Olivier; Eskens, Ferry; Tap, William D.; Rutkowski, Piotr; Chawla, Sant P.; Trent, Jonathan; Tugnait, Meera; Evans, Erica K.; Lauz, Tamieka; Zhou, Teresa; Roche, Maria; Wolf, Beni B.; Bauer, Sebastian; George, Suzanne
    Avapritinib in advanced PDGFRA D842V-mutant gastrointestinal stromal tumour (NAVIGATOR) : A multicentre, open-label, phase 1 trial
    In: The Lancet Oncology Vol. 21 (2020) Nr. 7, pp. 935 - 946
    ISSN: 1474-5488; 1470-2045
    Online Full Text: dx.doi.org/
  • Chabriat, Hugues; Bassetti, Claudio L; Marx, Ute; Audoli-Inthavong, Marie-Laure; Sors, Aurore; Lambert, Estelle; Wattez, Marine; Hermann, Dirk M.; Diener, Hans Christoph; Restore Brain Study Investigators
    Safety and efficacy of GABAA α5 antagonist S44819 in patients with ischaemic stroke : A multicentre, double-blind, randomised, placebo-controlled trial
    In: The Lancet Neurology Vol. 19 (2020) Nr. 3, pp. 226 - 233
    ISSN: 1474-4465; 1474-4422
    Online Full Text: dx.doi.org/
  • Dummer, Reinhard; Ascierto, Paolo A.; Nathan, Paul; Robert, Caroline; Schadendorf, Dirk
    Rationale for Immune Checkpoint Inhibitors plus Targeted Therapy in Metastatic Melanoma : A Review
    In: JAMA Oncology (2020) in press
    ISSN: 2374-2445; 2374-2437
    Online Full Text: dx.doi.org/
  • Liu, David; Schilling, Bastian; Liu, Derek; Sucker, Antje; Livingstone, Elisabeth; Jerby-Arnon, Livnat; Zimmer, Lisa; Gutzmer, Ralf; Satzger, Imke; Loquai, Carmen; Grabbe, Stephan; Vokes, Natalie; Margolis, Claire A.; Conway, Jake; He, Meng Xiao; Elmarakeby, Haitham; Dietlein, Felix; Miao, Diana; Tracy, Adam; Gogas, Helen; Goldinger, Simone M.; Utikal, Jochen; Blank, Christian U.; Rauschenberg, Ricarda; von Bubnoff, Dagmar; Krackhardt, Angela; Weide, Benjamin; Haferkamp, Sebastian; Kiecker, Felix; Izar, Ben; Garraway, Levi; Regev, Aviv; Flaherty, Keith; Paschen, Annette; Van Allen, Eliezer M.; Schadendorf, Dirk
    Author Correction: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma
    In: Nature Medicine Vol. 26 (2020) Nr. 7, pp. 1147
    ISSN: 1546-170X; 1078-8956
    Online Full Text: dx.doi.org/ (Open Access)
  • Cabrita, Rita; Lauss, Martin; Sanna, Adriana; Donia, Marco; Skaarup Larsen, Mathilde; Mitra, Shamik; Johansson, Iva; Phung, Bengt; Harbst, Katja; Vallon-Christersson, Johan; van Schoiack, Alison; Lövgren, Kristina; Warren, Sarah; Jirström, Karin; Olsson, Håkan; Pietras, Kristian; Ingvar, Christian; Isaksson, Karolin; Schadendorf, Dirk; Schmidt, Henrik; Bastholt, Lars; Carneiro, Ana; Wargo, Jennifer A.; Svane, Inge Marie; Jönsson, Göran
    Author Correction: Tertiary lymphoid structures improve immunotherapy and survival in melanoma
    In: Nature Vol. 580 (2020) Nr. 7801, pp. E1
    ISSN: 1476-4687; 0028-0836
    Online Full Text: dx.doi.org/
  • Subbiah, Vivek; Hu, Mimi I-Nan; Gainor, Justin F.; Mansfield, Aaron Scott; Alonso, Guzman; Taylor, Matthew H.; Zhu, Viola Weijia; Garrido Lopez, Pilar; Amatu, Alessio; Doebele, Robert C; Cassier, Philippe Alexandre; Keam, Bhumsuk; Schuler, Martin; Zhang, Hui; Clifford, Corinne; Palmer, Michael; Green, Jennifer; Turner, Christopher D.; Curigliano, Giuseppe
    Clinical activity of the RET inhibitor pralsetinib (BLU-667) in patients with RET fusion+ solid tumors.
    In: Journal of Clinical Oncology Vol. 38 (2020) Nr. 15_Suppl., pp. 109
    ISSN: 0732-183X; 1527-7755
    Online Full Text: dx.doi.org/
  • Long, Georgina V.; Lebbe, Celeste; Atkinson, Victoria; Mandalà, Mario; Nathan, Paul D.; Arance, Ana; Richtig, Erika; Yamazaki, Naoya; Robert, Caroline; Schadendorf, Dirk; Tawbi, Hussein Abdul-Hassan; Ascierto, Paolo Antonio; Ribas, Antoni; Flaherty, Keith; Pakhle, Neha; Masood, Aisha; Gasal, Eduard; Dummer, Reinhard
    The anti–PD-1 antibody spartalizumab in combination with dabrafenib and trametinib in advanced BRAF V600–mutant melanoma : Efficacy and safety findings from parts 1 and 2 of the Phase III COMBI-i trial
    In: Journal of Clinical Oncology Vol. 38 (2020) Nr. 15_Suppl., pp. 10028
    ISSN: 0732-183X; 1527-7755
    Online Full Text: dx.doi.org/
  • Hauschild, Axel; Dummer, Reinhard; Santinami, Mario; Atkinson, Victoria; Mandalà, Mario; Kirkwood, John M.; Chiarion Sileni, Vanna; Larkin, James M. G.; Nyakas, Marta; Dutriaux, Caroline; Haydon, Andrew Mark; Robert, Caroline; Mortier, Laurent; Schachter, Jacob; Dasgupta, Kohinoor; Gasal, Eduard; Tan, Monique; Long, Georgina V.; Schadendorf, Dirk
    Long-term benefit of adjuvant dabrafenib + trametinib (D+T) in patients (pts) with resected stage III BRAF V600–mutant melanoma : Five-year analysis of COMBI-AD
    In: Journal of Clinical Oncology Vol. 38 (2020) Nr. 15_Suppl., pp. 10001
    ISSN: 0732-183X; 1527-7755
    Online Full Text: dx.doi.org/
  • Dummer, Reinhard; Biette, Kelly; Gusenleitner, Daniel; Ramesh, Radha; Lebbe, Celeste; Atkinson, Victoria; Mandalà, Mario; Nathan, Paul D.; Arance, Ana; Richtig, Erika; Yamazaki, Naoya; Robert, Caroline; Schadendorf, Dirk; Tawbi, Hussein Abdul-Hassan; Ascierto, Paolo Antonio; Ribas, Antoni; Flaherty, Keith; Gasal, Eduard; Brase, Jan C.; Long, Georgina V.
    Effect of first-line spartalizumab + dabrafenib + trametinib on immunosuppressive features detected in peripheral blood and clinical outcome in patients (pts) with advanced BRAF V600–mutant melanoma
    In: Journal of Clinical Oncology Vol. 38 (2020) Nr. 15_Suppl., pp. 10034
    ISSN: 0732-183X; 1527-7755
    Online Full Text: dx.doi.org/
  • Janku, Filip; Elez, Elena; Iyer, Gopa; Yamamoto, Noboru; Tan, Daniel Shao-Weng; Stathis, Anastasios; Stammberger, Uz M.; Evans, Helen; Seroutou, Abdelkader; Mais, Anna; Schuler, Martin
    Phase I dose-finding study of oral ERK1/2 inhibitor LTT462 in patients (pts) with advanced solid tumors harboring MAPK pathway alterations
    In: Journal of Clinical Oncology Vol. 38 (2020) Nr. 15_Suppl., pp. 3640
    ISSN: 0732-183X; 1527-7755
    Online Full Text: dx.doi.org/
  • Falkenhorst, Johanna; Hamacher, Rainer; Reichardt, Peter; Ivanyi, Philipp; Kasper, Bernd; Hohenberger, Peter; Hermes, Barbara; Kostbade, Karina; Pink, Daniel; Sülberg, Heiko; Metzenmacher, Martin; Crysandt, Martina; Bauer, Sebastian
    Lower-dosing ponatinib in pre-treated GIST : Results of the POETIG phase II trial
    In: Journal of Clinical Oncology Vol. 38 (2020) Nr. 15_Suppl., pp. 11536
    ISSN: 0732-183X; 1527-7755
    Online Full Text: dx.doi.org/
  • Heinrich, Michael C.; George, Suzanne; Zalcberg, John Raymond; Bauer, Sebastian; Gelderblom, Hans; Schoffski, Patrick; Serrano, Cesar; Jones, Robin L.; Attia, Steven; D'Amato, Gina Z.; Chi, Ping; Reichardt, Peter; Becker, Claus C.; Meade, Julie Nicole; Ruiz-Soto, Rodrigo; von Mehren, Margaret; Blay, Jean-Yves
    Quality of life (QoL) and self-reported function with ripretinib in ≥4th-line therapy for patients with gastrointestinal stromal tumors (GIST) : Analyses from INVICTUS
    In: Journal of Clinical Oncology Vol. 38 (2020) Nr. 15_Suppl., pp. 11535
    ISSN: 0732-183X; 1527-7755
    Online Full Text: dx.doi.org/
  • Vincenzi, Bruno; Napolitano, Andrea; Nannini, Margherita; Fumagalli, Elena; Grignani, Giovanni; Martin Broto, Javier; Hindi, Nadia; Italiano, Antoine; Rutkowski, Piotr; Hohenberger, Peter; Brunello, Antonella; Gasperoni, Silvia; Joensuu, Heikki; Badalamenti, Giuseppe; Gennatas, Spyridon; De Pas, Tommaso Martino; Gronchi, Alessandro; Dei Tos, Angelo Paolo; Jones, Robin Lewis; Bauer, Sebastian
    Role of adjuvant imatinib dose in radically resected GIST harboring KIT exon 9 mutations
    In: Journal of Clinical Oncology Vol. 38 (2020) Nr. 15_Suppl., pp. 11533
    ISSN: 0732-183X; 1527-7755
    Online Full Text: dx.doi.org/
  • George, Suzanne; Heinrich, Michael C.; Zalcberg, John Raymond; Bauer, Sebastian; Gelderblom, Hans; Schoffski, Patrick; Serrano, Cesar; Jones, Robin L.; Attia, Steven; D'Amato, Gina Z.; Chi, Ping; Reichardt, Peter; Lacouture, Mario E.; Cha, Elva; Meade, Julie Nicole; Ruiz-Soto, Rodrigo; Blay, Jean-Yves; von Mehren, Margaret
    Safety profile of ripretinib, including impact of alopecia, and Palmar-Plantar Erythrodysesthesia Syndrome (PPES) on patient-reported outcomes (PROs), in ≥ fourth-line advanced gastrointestinal stromal tumors (GIST) : Analyses from INVICTUS
    In: Journal of Clinical Oncology Vol. 38 (2020) Nr. 15_Suppl., pp. 11539
    ISSN: 0732-183X; 1527-7755
    Online Full Text: dx.doi.org/
  • Joensuu, Heikki; Eriksson, Mikael; Sundby Hall, Kirsten; Reichardt, Annette; Hermes, Barbara; Schütte, Jochen; Cameron, Silke; Hohenberger, Peter; Jost, Philipp; Al-Batran, Salah-Eddin; Lindner, Lars H; Bauer, Sebastian; Wardelmann, Eva; Nilsson, Bengt E.; Kallio, Raija S.; Jaakkola, Panu; Junnila, Jouni; Alvegard, Thor; Reichardt, Peter
    Three versus one year of adjuvant imatinib for high-risk gastrointestinal stromal tumor (GIST) : Survival analysis of a randomized trial after 10 years of follow-up
    In: Journal of Clinical Oncology Vol. 38 (2020) Nr. 15_Suppl., pp. 11503
    ISSN: 0732-183X; 1527-7755
    Online Full Text: dx.doi.org/
  • Rischin, Danny; Khushalani, Nikhil I.; Schmults, Chrysalyne D.; Guminski, Alexander David; Chang, Anne Lynn S.; Lewis, Karl D.; Lim, Annette May Ling; Hernandez-Aya, Leonel Fernando; Hughes, Brett Gordon Maxwell; Schadendorf, Dirk; Hauschild, Axel; Stankevich, Elizabeth; Booth, Jocelyn; Li, Siyu; Chen, Zhen; Okoye, Emmanuel; Lowy, Israel; Fury, Matthew G.; Migden, Michael Robert
    Phase II study of cemiplimab in patients (pts) with advanced cutaneous squamous cell carcinoma (CSCC) : Longer follow-up
    In: Journal of Clinical Oncology Vol. 38 (2020) Nr. 15_Suppl.,
    ISSN: 0732-183X; 1527-7755
    Online Full Text: dx.doi.org/
  • Dummer, Reinhard; Lebbé, Celeste; Atkinson, Victoria; Mandalà, Mario; Nathan, Paul D.; Arance, Ana; Richtig, Erika; Yamazaki, Naoya; Robert, Caroline; Schadendorf, Dirk; Tawbi, Hussein A.; Ascierto, Paolo A.; Ribas, Antoni; Flaherty, Keith T.; Pakhle, Neha; Campbell, Catarina D.; Gusenleitner, Daniel; Masood, Aisha; Brase, Jan C.; Gasal, Eduard; Long, Georgina V.
    Combined PD-1, BRAF and MEK inhibition in advanced BRAF-mutant melanoma : safety run-in and biomarker cohorts of COMBI-i
    In: Nature Medicine Vol. 26 (2020) Nr. 10, pp. 1557 - 1563
    ISSN: 1546-170X; 1078-8956
    Online Full Text: dx.doi.org/
  • Nathan, Paul D.; Dummer, Reinhard; Long, G.V.; Ascierto, Paolo A.; Tawbi, Hussein A.; Robert, Caroline; Rutkowski, P.; Leonov, O.; Dutriaux, C.; Mandala, Mario; Lorigan, P.; Ferrucci, Pier Francesco; Flaherty, K.T.; Brase, Jan C.; Green, S.; Haas, T.; Masood, A.; Gasal, Eduard; Ribas, A.; Schadendorf, Dirk
    Spartalizumab plus dabrafenib and trametinib (Sparta-DabTram) in patients (pts) with previously untreated BRAF V600–mutant unresectable or metastatic melanoma : Results from the randomized part 3 of the phase III COMBI-i trial
    In: Annals of Oncology Vol. 31 (2020) Nr. Suppl. 4, pp. S1172
    ISSN: 0923-7534
    Online Full Text: dx.doi.org/
  • Gutzmer, Ralf; Eigentler, T.; Mohr, P.; Weichenthal, M.; Dücker, P.; Gebhardt, Christoffer; Göppner, D.; Haferkamp, S.; Kähler, Katharina C.; Meier, Friedegund; Pföhler, Claudia; Satzger, Imke; Sickmann, T.; Sindrilaru, Anca; Terheyden, P.; Ugurel, Selma; Ulrich, J.; Utikal, Jens; Weishaupt, C.; Schadendorf, Dirk
    Nivolumab (NIVO) monotherapy or combination therapy with ipilimumab (NIVO+IPI) in advanced melanoma patients with brain metastases : Real-world evidence from the German non-interventional study NICO
    In: Annals of Oncology Vol. 31 (2020) Nr. Suppl. 4, pp. 746 - S747
    ISSN: 0923-7534
    Online Full Text: dx.doi.org/
  • Blay, Jean-Yves; Serrano, César; Heinrich, Michael C.; Zalcberg, John; Bauer, Sebastian; Gelderblom, Hans; Schöffski, Patrick; Jones, Robin L; Attia, Steven; D'Amato, Gina; Chi, Ping; Reichardt, Peter; Meade, Julie; Shi, Kelvin; Ruiz-Soto, Rodrigo; George, Suzanne; von Mehren, Margaret
    Ripretinib in patients with advanced gastrointestinal stromal tumours (INVICTUS) : a double-blind, randomised, placebo-controlled, phase 3 trial
    In: The Lancet Oncology Vol. 21 (2020) Nr. 7, pp. 923 - 934
    ISSN: 1474-5488; 1470-2045
    Online Full Text: dx.doi.org/
  • Lang, Judith; Bohn, Patrick; Bhat, Hilal; Jastrow, Holger; Walkenfort, Bernd; Cansiz, Feyza; Fink, Julian; Bauer, Michael; Olszewski, Dominik; Ramos-Nascimento, Ana; Duhan, Vikas; Friedrich, Sarah-Kim; Becker-Flegler, Katrin; Krawczyk, Adalbert; Edwards, Michael J.; Burchert, Andreas; Huber, Magdalena; Friebus-Kardash, Justa; Göthert, Joachim Rudolf; Hardt, Cornelia; Probst, Hans Christian; Schumacher, Fabian; Köhrer, Karl; Kleuser, Burkhard; Babiychuk, Eduard B.; Sodeik, Beate; Seibel, Jürgen; Greber, Urs F.; Lang, Philipp A.; Gulbins, Erich; Lang, Karl S.
    Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease
    In: Nature Communications Vol. 11 (2020) Nr. 1, pp. 1338
    ISSN: 2041-1723
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Khatib-Massalha, Eman; Bhattacharya, Suditi; Massalha, Hassan; Biram, Adi; Golan, Karin; Kollet, Orit; Kumari, Anju; Avemaria, Francesca; Petrovich-Kopitman, Ekaterina; Gur-Cohen, Shiri; Itkin, Tomer; Brandenburger, Isabell; Spiegel, Asaf; Shulman, Ziv; Gerhart-Hines, Zachary; Itzkovitz, Shalev; Gunzer, Matthias; Offermanns, Stefan; Alon, Ronen; Ariel, Amiram; Lapidot, Tsvee
    Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling
    In: Nature Communications Vol. 11 (2020) Nr. 1, pp. 3547
    ISSN: 2041-1723
    Online Full Text: dx.doi.org/ (Open Access)
  • Sijbesma, Eline; Visser, Emira; Plitzko, Kathrin; Thiel, Philipp; Milroy, Lech-Gustav; Kaiser, Markus; Brunsveld, Luc; Ottmann, Christian
    Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactions
    In: Nature Communications Vol. 11 (2020) Nr. 1, pp. 3954
    ISSN: 2041-1723
    Online Full Text: dx.doi.org/ (Open Access)
  • Schuler, Martin
    Inhibiting fibroblast growth factor receptors in cancer – the next generation
    In: Annals of Oncology Vol. 31 (2020) Nr. 10, pp. 1285 - 1286
    ISSN: 1569-8041; 0923-7534
    Online Full Text: dx.doi.org/
  • Dykun, Iryna; Mahabadi, Amir Abbas; Rassaf, Tienush
    A clinical perspective on the 2019 ESC/EAS guidelines for the management of dyslipidaemias: PCSK-9 inhibitors for all?
    In: European Heart Journal Vol. 41 (2020) Nr. 24, pp. 2331
    ISSN: 1522-9645
    Online Full Text: dx.doi.org/
  • Petersdorf, Effie W.; Bengtsson, Mats; De Santis, Dianne; Dubois, Valerie; Fleischhauer, Katharina; Gooley, Ted; Horowitz, Mary; Madrigal, J Alejandro; Malkki, Mari; McKallor, Caroline; Morishima, Yasuo; Oudshoorn, Machteld; Spellman, Stephen R.; Villard, Jean; Stevenson, Phil; Carrington, Mary
    Role of HLA-DP Expression in Graft-Versus-Host Disease After Unrelated Donor Transplantation
    In: Journal of Clinical Oncology Vol. 38 (2020) Nr. 24, pp. 2712 - 2718
    ISSN: 1527-7755; 0732-183X
    Online Full Text: dx.doi.org/
  • Bazinet, Michel; Pântea, Victor; Placinta, Gheorghe; Moscalu, Iurie; Cebotarescu, Valentin; Cojuhari, Lilia; Jimbei, Pavlina; Iarovoi, Liviu; Smesnoi, Valentina; Musteata, Tatiana; Jucov, Alina; Dittmer, Ulf; Krawczyk, Adalbert; Vaillant, Andrew
    Safety and Efficacy of 48 Weeks REP 2139 or REP 2165, Tenofovir Disoproxil, and Pegylated Interferon Alfa-2a in Patients With Chronic HBV Infection Naïve to Nucleos(t)ide Therapy
    In: Gastroenterology Vol. 158 (2020) Nr. 8, pp. 2180 - 2194
    ISSN: 1528-0012; 0016-5085
    Online Full Text: dx.doi.org/

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