There were 1167 publications found

• Liu, Mei; Wei, You; Weber, Lisa-Marie; Mladenov, Emil; Lin, Xixi; Mladenova, Veronika; Shafaat, Ramtin Omid; Pantelias, Gabriel E.; Gkika, Eleni; Stuschke, Martin; Soni, Aashish; Iliakis, George

  Condensins regulate resection-dependent DNA double-strand break repair pathways in replicated chromatin

  In: Nucleic Acids Research, Vol. 54, 2026, Nr. 4, gkag076

  DOI (Open Access)
• Peng, JuanFei; Yang, JiaJin; Antonopoulou, Georgia; Fang, Rui; Adhikari, Bikash; Vogt, Markus; Wolf, Elmar; Sun, Chong; Du, Shangce; Godfrey, Laura; Gupta, Aayush; Trajkovic-Arsic, Marija; Teichmann, Nicole; Grünwald, Barbara T.; Krebs, Niklas; Steiger, Katja; Mogler, Carolin; Althoff, Kristina; Wang, Xin; Giglio, Giovanni; Liffers, Sven-Thorsten; Savvatakis, Konstantinos; Braren, Rickmer; Lawlor, Rita T.; Scarpa, Aldo; Behrens, Diana; Lang, Karl S.; Cheung, Phyllis F.; Siveke, Jens T.

  Combined targeted and epigenetic-based therapy enhances antitumor immunity by stabilizing GATA6-dependent MHCI expression in pancreatic ductal adenocarcinoma

  In: Nature Communications, Vol. 17, 2026, Nr. 1, 1476

  DOI (Open Access)
• Kracht, Matthias; Kröning, Alexander; van den Boom, Johannes; Gahlot, Pinki; Koska, Sandra; Kiss, Leo; Meyer, Hemmo

  The accessory adapters FAF1, FAF2, and UBXN7 accelerate proteasomal degradation by increasing prior p97-mediated substrate unfolding

  In: Science Advances, Vol. 12, 2026, Nr. 10, eaea7381

  DOI (Open Access)
• Kremer, Nora; Mueller, Franziska; Nguyen, Hang; Schulz, Louisa; Popp, Tanja; Artes, Elena; Wolters, Julian; Renner, Michael; Vetter, Ingrid; Maffini, Stefano; Robles, Maria S.; Musacchio, Andrea; Bange, Tanja

  CUL4A-DDB1-DCAF10 is an N-recognin for N-terminally acetylated Src kinases

  In: Nature Communications, Vol. 17, 2026, Nr. 1, 132

  DOI (Open Access)
• Walstein, Kai; Hill, Louisa; Vogt, Doro; Oberste-Lehn, Lina; Janning, Petra; Vetter, Ingrid R; Pan, Dongqing; Musacchio, Andrea

  M18BP1 valency and a distributed interaction footprint determine epigenetic centromere specification in humans

  In: The EMBO Journal, 2026, in press

  DOI (Open Access)
• Esposito-Verza, Arianna; Conti, Duccio; Rodrigues Pedroso, Paulo D.; Oberste-Lehn, Lina; Koerner, Carolin; Wohlgemuth, Sabine; Mansurkhodzhaev, Artem; Vetter, Ingrid R.; Pesenti, Marion E.; Musacchio, Andrea

  Molecular requirements for PLK1 activation by T-loop phosphorylation

  In: The EMBO Journal, Vol. 45, 2026, Nr. 5, pp. 1496 – 1536

  DOI (Open Access)
• Li, Xin; Lebeaupin, Cynthia; Kadianaki, Aikaterini; Druelle-Cedano, Clementine; Vesper, Niklas; Rennert, Charlotte; Huguet-Pradell, Júlia; Gomez Ramos, Borja; Fan, Chaofan; Piecyk, Robert Stefan; Zizmare, Laimdota; Ramadori, Pierluigi; Li, Luqing; Frick, Lukas; Qiu, Menjie; Zhang, Cangang; Martins Nascentes Melo, Luiza; Ranvir, Vikas Prakash; Shen, Peng; Hanselmann, Johannes; Kosla, Jan; Fernández-Vaquero, Mirian; Vucur, Mihael; Baskaran, Praveen; Bao, Xuanwen; Coleman, Olivia I.; Tang, Yingyue; Cetin, Miray; Chen, Zhouji; Jang, Insook; Del Prete, Stefania; Rahbari, Mohammad; Zhang, Peng; Pham, Timothy V.; Hou, Yushan; Sun, Aihua; Gu, Li; Kim, Laura C.; Rothermel, Ulrike; Heide, Danijela; Ali, Adnan; Gallage, Suchira; Talvard-Balland, Nana; Piqué-Gili, Marta; Gris-Oliver, Albert; Bevilacqua, Alessio; Schlicker, Lisa; Duffey, Alec; Unger, Kristian; Szydlowska, Marta; Hetzer, Jenny; Odom, Duncan T.; Machauer, Tim; Bucci, Daniele; Sant, Pooja; Lee, Jun-Hoe; Rösler, Jonas; Meckelmann, Sven; Schreck, Johannes; Murray, Sue; Simon, M. Celeste; Nahnsen, Sven; Schulze, Almut; Ho, Ping-Chih; Jugold, Manfred; Breuhahn, Kai; Mallm, Jan-Philipp; Schirmacher, Peter; Roth, Susanne; Rahbari, Nuh; Tschaharganeh, Darjus F.; Roessler, Stephanie; Goeppert, Benjamin; Bengsch, Bertram; Andrieux, Geoffroy; Boerries, Melanie; Malek, Nisar P.; Prinz, Marco; Weber, Achim; Zeiser, Robert; Tamayo, Pablo; Bronsert, Peter; Kurowski, Konrad; Thimme, Robert; Yuan, Detian; Carretero, Rafael; Luedde, Tom; Pinyol, Roser; Hartmann, Felix J.; Karin, Michael; Tasdogan, Alpaslan; Trautwein, Christoph; Mall, Moritz; Hofmann, Maike; Llovet, Josep M.; Haller, Dirk; Kaufman, Randal J.; Heikenwälder, Mathias

  Activated ATF6α is a hepatic tumour driver restricting immunosurveillance

  In: Nature, 2026, in press

  DOI (Open Access)
• Anker, Markus S.; Anker, Stefan D.; Rassaf, Tienush

  The EMPATICC-trial : should location shape therapy?

  In: European Heart Journal, 2026, in press

  DOI
• Zhang, Ruirui; Liu, Jie; Gasper, Raphael; Unger, Anke; Kaschani, Farnusch; Kaiser, Markus; Janning, Petra; Waldmann, Herbert

  Covalent modification of a glutamic acid inspired by HaloTag technology

  In: Nature Communications, Vol. 17, 2026, Nr. 1, 1257

  DOI (Open Access)
• Dummer, Reinhard; Guo, Jun; Luke, Jason J; Carlino, Matteo S; Schadendorf, Dirk; Khattak, Muhammad A; Hauschild, Axel; Ascierto, Paolo A; Chen, Yu; Shin, Sang Joon; Rutkowski, Piotr; Luo, Zhiguo; Chen, Jing; Rivalland, Gareth; Coetzee, Corlia; Ribas, Antoni; Mujika, Karmele; Markel, Gal; Villarroel, Rodrigo U; Dizdar, Omer; Caglevic, Christian; Grebennik, Dmitri; Donovan, Kevin; Krepler, Clemens; Long, Georgina V

  Vibostolimab coformulated with pembrolizumab versus pembrolizumab alone as adjuvant therapy for high-risk stage IIB–IV melanoma (KEYVIBE-010) : A randomised, double-blind, phase 3 study

  In: The Lancet Oncology, Vol. 27, 2026, Nr. 3, pp. 327 – 339

  DOI (Open Access)
• Anker, Markus S.; Mahabadi, Amir Abbas; Totzeck, Matthias; Tewes, Mitra; Khan, Muhammad Shahzeb; Mincu, Raluca; Hendgen-Cotta, Ulrike B.; Michel, Lars; Mathew, Baicy; Drescher, Ophelia; Schuler, Martin; Keller, Ulrich; Rieger, Kathrin; Ahn, Johann; Bullinger, Lars; Modest, Dominik P.; Denecke, Corinna; Kretzler, Lucie; Ramer, Luisa V.; Krug, Danara; Landmesser, Ulf; Lehmann, Lorenz H.; Frey, Norbert; Bercker, Sven; Laufs, Ulrich; Böhm, Michael; Mahfoud, Felix; Merkely, Bela; Diek, Monika; Butler, Javed; Veiser, Anja; Heise, Tim; Hellmich, Martin; Placzek, Marius; Friede, Tim; Anker, Stefan D.; Rassaf, Tienush

  Heart failure therapy in patients with advanced cancer receiving specialized palliative care (EMPATICC trial)

  In: European Heart Journal, Vol. 47, 2026, Nr. 9, pp. 1034 – 1046

  DOI (Open Access)
• Keyl, Julius; Hosch, René; Hörst, Fabian; Keyl, Philipp; Dada, Amin; Haubold, Johannes; Straus, Jannis; Egger, Jan; Stahler, Arndt; Kurreck, Annika; Ballhausen, Alexej; Stintzing, Sebastian; Fruehauf, Stefan; Müller, Lothar; Alig, Annabel H S; Trarbach, Tanja; Hartmann, Sylvia; Nensa, Felix; Kleesiek, Jens; Kasper, Stefan; Schuler, Martin; Modest, Dominik P.

  Deep Learning-Derived Sarcopenia Marker Predicts Benefit from Anti-EGFR Therapy in Patients with RAS Wild-type Metastatic Colorectal Cancer

  In: Clinical Cancer Research, Vol. 32, 2026, Nr. 5, pp. 938 – 946

  DOI (Open Access)
• Gorzkiewicz, Michal; Noseir, Soha; Vengurlekar, Mandar; Ghosh, Mitrajit; Katahira, Ichiro; Abromavičiūtė, Džiuljeta; Gerling-Driessen, Ulla; Bonda, Lorand; Rähse, Nick; Lapsien, Marco; Bockholt, Sabrina; Bergmann, Ann Kathrin; Kostadinovska, Konstantina; Fraii, Hafssa; Lang, Karl S.; Oestereich, Lisa; Gohlke, Holger; Hartmann, Laura; Lang, Philipp A

  Sulfated glycosaminoglycans inhibit LCMV entry and modulate antiviral immunity and pathology

  In: EMBO Molecular Medicine, 2026, in press

  DOI (Open Access)
• Elwy, Abdelrahman; Abdelrahman, Hossam; Specht, Julia; Ewert, Gina M.; Friebus-Kardash, Justa; Dhiman, Swati; Falkenstein, Julia; Christ, Theresa Charlotte; Wiebeck, Elisa; Shamoon, Arzoo; Leimkühler, Nils B.; Gramberg, Thomas; Russ, Alina; Kalinke, Ulrich; Kuang, Fei; Sutter, Kathrin; Kopf, Manfred; Mack, Matthias; Hansen, Wiebke; Nimmerjahn, Falk; Lang, Karl S.

  Type I IFN-dependent FcγRIV signaling in murine monocytes promotes lethal anaphylaxis during viral infections

  In: The Journal of Clinical Investigation (JCI), Vol. 136, 2026, Nr. 4

  DOI (Open Access)
• Bolli, Evangelia; Wirapati, Pratyaksha; Hicham, Mehdi; Xie, Yuxuan; Siwicki, Marie; Duval, Florent; Goubet, Anne-Gaëlle; Kiss, Máté; Zitti, Béatrice; Zwahlen, Thomas; Mcdowell, Sheri; Bill, Ruben; Angerani, Simona; Engblom, Camilla; Anderson, Seth; Jiang, Aiping; Hartley, Oliver; Sykes, David B.; Jankovic, Maja; Fournier, Nadine; Gunzer, Matthias; Tarussio, David; Tissot, Stéphanie; Sadow, Peter M.; Faquin, William C.; Sade-Feldman, Moshe; Weissleder, Ralph; Pai, Sara; Mercier, François; Manguso, Robert; Pittet, Mikaël J.

  CCL3 is produced by aged neutrophils across cancers and promotes tumor growth

  In: Cancer Cell, Vol. 44, 2026, Nr. 3, pp. 624 – 640.e12

  DOI (Open Access)
• Haase, Max A. B.; Lazar-Stefanita, Luciana; Baudry, Lyam; Wudzinska, Aleksandra; Zhou, Xiaofan; Rokas, Antonis; Hittinger, Chris Todd; Pfander, Boris; Musacchio, Andrea; Boeke, Jef D.

  Ancient co-option of LTR retrotransposons as yeast centromeres

  In: Nature, 2026, in press

  DOI (Open Access)
• Albers, Malena; Bosse, Lydia; Schröter, Larissa; Junemann, Anna-Maria T.; Rossdam, Charlotte; Hartmann, Maike; Grove, Melanie; Litfin, Thomas; Egger, Anna-Sophia; Kwiatkowski, Marcel; Thedieck, Kathrin; Zocher, Georg; Buettner, Falk F. R.; Malde, Alpeshkumar K.; von Itzstein, Mark; Mühlenhoff, Martina

  Interplay of SLC33A1-dependent and -independent Golgi sialic acid O-acetylation in CASD1 catalysis

  In: Nature Communications, Vol. 17, 2026, Nr. 1, 3156

  DOI (Open Access)
• Giuranna, Johanna; Zheng, Yiran; Brandt, Matthäus; Jall, Sigrid; Mukherjee, Amrita; Shankhwar, Soni; Renner, Simone; Kurapati, Nirup Kumar; May, Caroline; Peters, Triinu; Herpertz-Dahlmann, Beate; Seitz, Jochen; de Zwaan, Martina; Herzog, Wolfgang; Ehrlich, Stefan; Zipfel, Stephan; Giel, Katrin; Egberts, Karin; Burghardt, Roland; Föcker, Manuel; Marcus, Katrin; Keyvani, Kathy; Müller, Timo D.; Schmitz, Frank; Rajcsanyi, Luisa Sophie; Hinney, Anke

  Genetic and functional analyses of CTBP2 in anorexia nervosa and body weight regulation

  In: Molecular Psychiatry, Vol. 30, 2025, Nr. 5, pp. 1836 – 1846

  DOI (Open Access)
• Schwarz, Tatjana; Ptok, Johannes; Damagnez, Maximilian; Menne, Christopher; Alizei, Elahe Salimi; Lang-Meli, Julia; Maas, Michelle; Habermann, Daniel; Hoffmann, Daniel; Schulze zur Wiesch, Julian; Lauer, Georg; Kefalakes, Helenie; Cornberg, Markus; Kraft, Anke RM.; Gliga, Smaranda; Bock, Hans H.; Horn, Peter A.; Maini, Mala K.; Thimme, Robert; Wedemeyer, Heiner; Nattermann, Jacob; Heinemann, Falko M.; Luedde, Tom; Neumann-Haefelin, Christoph; Walker, Andreas; Timm, Jörg

  HBV shows different levels of adaptation to HLA class I-associated selection pressure correlating with markers of replication

  In: Journal of Hepatology, Vol. 82, 2025, Nr. 5, pp. 805 – 815

  DOI (Open Access)
• Lopez, Juanita; Powles, Thomas; Braiteh, Fadi; Siu, Lillian L.; LoRusso, Patricia; Friedman, Claire F.; Balmanoukian, Ani S.; Gordon, Michael; Yachnin, Jeffrey; Rottey, Sylvie; Karydis, Ioannis; Fisher, George A.; Schmidt, Marcus; Schuler, Martin; Sullivan, Ryan J.; Burris, Howard A.; Galvao, Vladimir; Henick, Brian S.; Dirix, Luc; Jaeger, Dirk; Ott, Patrick A.; Wong, Kit Man; Jerusalem, Guy; Schiza, Aglaia; Fong, Lawrence; Steeghs, Neeltje; Leidner, Rom S.; Rittmeyer, Achim; Laurie, Scott A.; Gort, Eelke; Aljumaily, Raid; Melero, Ignacio; Sabado, Rachel L.; Rhee, Ina; Mancuso, Michael R.; Muller, Lars; Fine, Gregg D.; Yadav, Mahesh; Kim, Leesun; Leveque, Vincent J. P.; Robert, Alberto; Darwish, Martine; Qi, Ting; Zhu, Jiawen; Zhang, Jingbin; Twomey, Patrick; Rao, Gautham K.; Low, Donald W.; Petry, Chris; Lo, Amy A.; Schartner, Jill M.; Delamarre, Lélia; Mellman, Ira; Löwer, Martin; Müller, Felicitas; Derhovanessian, Evelyna; Cortini, Andrea; Manning, Luisa; Maurus, Daniel; Brachtendorf, Sebastian; Lörks, Verena; Omokoko, Tana; Godehardt, Eva; Becker, Dirk; Hawner, Christine; Wallrapp, Christine; Albrecht, Christian; Kröner, Christoph; Tadmor, Arbel D.; Diekmann, Jan; Vormehr, Mathias; Jork, Anette; Paruzynski, Anna; Lang, Maren; Blake, Jonathon; Hennig, Oliver; Kuhn, Andreas N.; Sahin, Ugur; Türeci, Özlem; Camidge, D. Ross

  Autogene cevumeran with or without atezolizumab in advanced solid tumors: a phase 1 trial

  In: Nature Medicine, Vol. 31, 2025, Nr. 1, pp. 152 – 164

  DOI (Open Access)
• Klein, Lukas; Tu, Mengyu; Krebs, Niklas; Urbach, Laura; Grimm, Daniela; Latif, Muhammad Umair; Penz, Frederike; Blandau, Anna; Wu, Xueyan; Samuel, Rebecca Diya; Küffer, Stefan; Wegwitz, Florian; Chan, Nathan; Aliar, Kazeera; Vyas, Foram; Kishore, Uday; Hessmann, Elisabeth; Trumpp, Andreas; Espinet, Elisa; Papantonis, Argyris; Khokha, Rama; Ellenrieder, Volker; Grünwald, Barbara; Singh, Shiv K.

  Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response in pancreatic cancer

  In: Nature Communications, Vol. 16, 2025, Nr. 1, 335

  DOI (Open Access)
• Cai, Ling; Hammond, Nia G.; Tasdogan, Alpaslan; Alsamraae, Massar; Yang, Chendong; Cameron, Robert B.; Quan, Peiran; Solmonson, Ashley; Gu, Wen; Pachnis, Panayotis; Kaur, Mayher; Chang, Brianna K.; Zhou, Qin; Hensley, Christopher T.; Do, Quyen N.; Martins Nascentes Melo, Luiza; Ubellacker, Jessalyn M.; Kaushik, Akash; Clare, Maia G.; Alcazar, Isabel N.; Kurylowicz, Katarzyna; Marcuccilli, Joseph D.; Allies, Gabriele; Kutritz, Andrea; Klode, Joachim; Ramesh, Vijayashree; Rogers, Thomas J.; Rao, Aparna D.; Crentsil, Hannah E.; Li, Hong; Brister, Fang; McDaniel, Phyllis; Xu, Xiaohong; Evers, Bret M.; Zacharias, Lauren G.; Sudderth, Jessica; Xu, Jian; Mathews, Thomas P.; Oliver, Dwight; Minna, John D.; Waters, John; Morrison, Sean J.; Kernstine, Kemp H.; Faubert, Brandon; DeBerardinis, Ralph J.

  High Glucose Contribution to the TCA Cycle Is a Feature of Aggressive Non-Small Cell Lung Cancer in Patients

  In: Cancer Discovery, Vol. 15, 2025, Nr. 4, pp. 702 – 716

  DOI (Open Access)
• Wolchok, Jedd D.; Chiarion-Sileni, Vanna; Rutkowski, Piotr; Cowey, C. Lance; Schadendorf, Dirk; Wagstaff, John; Queirolo, Paola; Dummer, Reinhard; Butler, Marcus O.; Hill, Andrew G.; Postow, Michael A.; Gaudy-Marqueste, Caroline; Medina, Theresa; Lao, Christopher D.; Walker, John; Márquez-Rodas, Iván; Haanen, John B. A. G.; Guidoboni, Massimo; Maio, Michele; Schöffski, Patrick; Carlino, Matteo S.; Sandhu, Shahneen; Lebbé, Céleste; Ascierto, Paolo A.; Long, Georgina V.; Ritchings, Corey; Nassar, Ayman; Askelson, Margarita; Benito, Melanie Pe; Wang, Wenjia; Hodi, F. Stephen; Larkin, James; CheckMate 067 Investigators

  Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma

  In: The New England Journal of Medicine, Vol. 392, 2025, Nr. 1, pp. 11 – 22

  DOI, Online Full Text (Open Access)
• Müller, Marion; Schubert, Torben; Welke, Cornelius; Maske, Tibor; Patschkowski, Thomas; Donhauser, Elfi; Heinen-Weiler, Jacqueline; Hormann, Felix-Levin; Heiles, Sven; Schulz, Tina Johanna; Lengenfelder, Luisa Andrea; Landwehrjohann, Lucia; Vogt, Elisa Theres; Stratmann, Bernd; Hense, Jurek; Lüdtke, Simon; Düfer, Martina; Tolstik, Elena; Dierks, Johann; Lorenz, Kristina; Huxohl, Tamino; Reil, Jan-Christian; Sequeira, Vasco; Schopfer, Francisco Jose; Freeman, Bruce A.; Rudolph, Volker; Schlomann, Uwe; Klinke, Anna

  Nitro-oleic acid enhances mitochondrial metabolism and ameliorates heart failure with preserved ejection fraction in mice

  In: Nature Communications, Vol. 16, 2025, Nr. 1, 3933

  DOI (Open Access)
• Haggenmüller, Sarah; Wies, Christoph; Abels, Julia; Winterstein, Jana T.; Heinlein, Lukas; Nogueira Garcia, Carina; Utikal, Jochen S.; Wohlfeil, Sebastian A.; Meier, Friedegund; Hobelsberger, Sarah; Gellrich, Frank F.; Sergon, Mildred; Hauschild, Axel; French, Lars E.; Heinzerling, Lucie; Schlager, Justin G.; Ghoreschi, Kamran; Schlaak, Max; Hilke, Franz J.; Poch, Gabriela; Korsing, Sören; Sarfert, Cosimo; Berking, Carola; Heppt, Markus V.; Erdmann, Michael; Haferkamp, Sebastian; Drexler, Konstantin; Schadendorf, Dirk; Sondermann, Wiebke; Goebeler, Matthias; Schilling, Bastian; Kather, Jakob Nikolas; Fröhling, Stefan; Llamas-Velasco, Mar; Requena, Luis C.; Ferrara, Gerardo; Fernandez-Figueras, Maite; Fraitag, Sylvie; Müller, Cornelia S. L.; Starz, Hans; Kutzner, Heinz; Barnhill, Raymond; Carr, Richard; Resnik, Kenneth S.; Braun, Stephan Alexander; Holland-Letz, Tim; Brinker, Titus J.

  Discordance, accuracy and reproducibility study of pathologists’ diagnosis of melanoma and melanocytic tumors

  In: Nature Communications, Vol. 16, 2025, Nr. 1, 789

  DOI (Open Access)
• Pekayvaz, Kami; Kilani, Badr; Joppich, Markus; Eivers, Luke; Brambs, Sophia; Knottenberg, Viktoria; Akgöl, Sezer; Yue, Keyang; Li, Lukas; Martinez-Navarro, Alejandro; Kaiser, Rainer; Meißner, Nina; Schulz, Heiko; Belz, Larissa; Akhalkatsi, Anastassia; Stockhausen, Sven; Mueller, Tonina T.; Millonig, Simon; Hartelt, Lea; Gold, Christoph; Janjic, Aleksandar; Polewka, Vivien; Wendler, Franziska; Droste zu Senden, Augustin; Titova, Anna; Leunig, Alexander; Voelkl, Michael; Engelmann, Bernd; Hernandez Petzsche, Moritz R.; Boeckh-Behrens, Tobias; Liebig, Thomas; Winning, Sandra; Fandrey, Joachim; Dichgans, Martin; Enard, Wolfgang; Zimmer, Ralf; Tiedt, Steffen; Massberg, Steffen; Nicolai, Leo; Stark, Konstantin

  Immunothrombolytic monocyte-neutrophil axes dominate the single-cell landscape of human thrombosis and correlate with thrombus resolution

  In: Immunity, Vol. 58, 2025, Nr. 5, pp. 1343 – 1358.e13

  DOI (Open Access)
• Zhao, Ben; Fang, Rui; Schürmann, Hendrik; Hemmer, Erik Jan; Mayer, Gina Lauren; Trajkovic-Arsic, Marija; Althoff, Kristina; Yang, Jiajin; Godfrey, Laura; Liffers, Sven T.; Savvatakis, Konstantinos; Dorsch, Madeleine; Grüner, Barbara M.; Hahn, Stephan; Remke, Marc; Lueong, Smiths S.; Siveke, Jens T.

  PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma

  In: Cell Reports, Vol. 44, 2025, Nr. 4, 115541

  DOI (Open Access)
• Skoulidis, Ferdinandos; Li, Bob T.; de Langen, Adrianus Johannes; Hong, David S.; Lena, Herve; Wolf, Juergen; Dy, Grace K.; Curioni Fontecedro, Alessandra; Tomasini, Pascale; Velcheti, Vamsidhar; van der Wekken, Anthonie J.; Dooms, Christophe; Paz-Ares Rodriguez, Luis; Mountzios, Giannis; Sacher, Adrian; Nadal, Ernest; Couraud, Sebastien; Kim, Sang-We; O’Byrne, Kenneth; Rocco, Danilo; Toyozawa, Ryo; Chmielewska, Izabela; Lindsay, Colin R.; Hindoyan, Antreas; Mukundan, Lata; Wilmanski, Tomasz; Anderson, Abraham; Ardito-Abraham, Christine; Pati, Amrita; Reddy, Anita; Mehta, Bhakti; Schuler, Martin

  Molecular determinants of sotorasib clinical efficacy in KRASG12C-mutated non-small-cell lung cancer

  In: Nature Medicine, Vol. 31, 2025, Nr. 8, pp. 2755 – 2767

  DOI (Open Access)
• Usama, Muhammad; Razzaq, Samad; Hättig, Christof; Steinmann, Stephan N.; Exner, Kai S.

  Oxygen evolution reaction on IrO₂(110) is governed by Walden-type mechanisms

  In: Nature Communications, Vol. 16, 2025, Nr. 1, 6137

  DOI (Open Access)
• Maassen, Fabienne; Le-Trilling, Vu Thuy Khanh; Betke, Luisa; Bracht, Thilo; Siegmund, Corinna; Bayer, Malte; Katschinski, Benjamin; Belter, Antonia; Becker, Tanja; Mennerich, Denise; Voigt, Sebastian; Frappier, Lori; Sitek, Barbara; Fleischhauer, Katharina; Trilling, Mirko

  The human cytomegalovirus-encoded pUS28 antagonizes CD4+ T cell recognition by targeting CIITA

  In: eLife, Vol. 14, 2025, e96414

  DOI, Online Full Text (Open Access)
• Ronnacker, Julian; Müller, Philippe J.; Mikesch, Jan-Henrik; Zukunft, Sven; Weinbergerová, Barbora; Šrámek, Jiří; Valka, Jan; Novak, Jan; Zak, Pavel; Szotkowski, Tomas; Koristek, Zdenek; Krekeler, Carolin; Unglaub, Julia M.; Sauer, Tim; Ruhnke, Leo; Kraus, Sabrina; Schaffrath, Judith; Müller, Lutz P.; Kaes, Sabrina; Niemann, Dirk; Fransecky, Lars; Hess, Patrick P.; Crysandt, Martina; Jost, Edgar; Millo, Joana; Gaertner, Johannes; Repp, Roland; Jentzsch, Madlen; Hoppe, Lea; Klein, Stefan; Modemann, Franziska; Michalowski, Nina; Fischbach, Klaudia; Blau, Wolfgang; Ruhs, Marion; Ritter, Markus; Lohmeyer, Julian; Steffen, Björn; Hauser, Sarah; Kaufmann, Martin; Krause, Stefan W.; Knabe, Ricarda; Spiekermann, Karsten; Serve, Hubert; Platzbecker, Uwe; Baldus, Claudia D.; Müller-Tidow, Carsten; Lenz, Georg; Reinhardt, Christian; Mayer, Jirí; Bornhäuser, Martin; Röllig, Christoph; Schliemann, Christoph; Hanoun, Maher

  Gemtuzumab ozogamicin in first-line treatment of CBF-AML : Insights from a retrospective multi-center analysis

  In: Leukemia, Vol. 39, 2025, Nr. 9, pp. 2174 – 2180

  DOI (Open Access)
• Rodier, Clement; Estabrook, Ian D.; Chan, Eunice HoYee; Rice, Gavin; Loreau, Vincent; Raunser, Stefan; Görlich, Dirk; Friedrich, Benjamin M.; Schnorrer, Frank

  Muscle growth by sarcomere divisions

  In: Science Advances, Vol. 11, 2025, Nr. 28, eadw9445

  DOI (Open Access)
• Kim, Jinjong; Usama, Muhammad; Exner, Kai; Joo, Sang Hoon

  Renaissance of Chlorine Evolution Reaction : Emerging Theory and Catalytic Materials

  In: Angewandte Chemie International Edition, Vol. 64, 2025, Nr. 1, e202417293

  DOI (Open Access)
• Ng’ang’a, Peter Njenga; Folz, Julian; Kucher, Svetlana; Roderer, Daniel; Xu, Ying; Sitsel, Oleg; Belyy, Alexander; Prumbaum, Daniel; Kühnemuth, Ralf; Assafa, Tufa E.; Dong, Min; Seidel, Claus A.M.; Bordignon, Enrica; Raunser, Stefan

  Multistate kinetics of the syringe-like injection mechanism of Tc toxins

  In: Science Advances, Vol. 11, 2025, Nr. 1, eadr2019

  DOI (Open Access)
• Pabst, Kim M; Weber, Manuel; Laschinsky, Christina; Sandach, Patrick; Bartel, Timo; Küper, Alina T; Kessler, Lukas; Trajkovic-Arsic, Marija; Eckstein, Markus; Gilman, Elena; Nader, Michael; Barbato, Francesco; Podleska, Lars; Hadaschik, Boris; Hamacher, Rainer; Kersting, David; von Ostau, Nicola; von Tresckow, Bastian; Kaelberlah, Hans-Peter; Kesch, Claudia; Kuemmel, Sherko; Reinacher-Schick, Anke; Schuler, Martin; Siveke, Jens; Grünwald, Viktor; Herrmann, Ken; Fendler, Wolfgang P.

  [⁶⁸Ga]Ga-FAPI-46 PET accuracy for cancer imaging with histopathology validation : A single-centre, single-arm, interventional, phase 2 trial

  In: The Lancet Oncology, Vol. 26, 2025, Nr. 9, pp. 1204 – 1214

  DOI (Open Access)
• Kähler, K.C.; Hassel, J.C.; Ziemer, M.; Rutkowski, P.; Meier, F.; Flatz, L.; Gaudy-Marqueste, C.; Zimmer, Lisa; Santinami, M.; Russano, F.; von Wasielewski, I.; Eigentler, T.K.; Maio, M.; Zalaudek, I.; Haferkamp, S.; Quaglino, P.; Welzel, J.; Röcken, C.; Enk, A.; Simon, J.-C.; Świtaj, T.; Garzarolli, M.; Amaral, T.; Malissen, N.; Livingstone, Elisabeth; Elia, G.; Covelli, A.; Lorizzo, K.; Neri, D.; Mulatto, S.; Parca, A.; Pizzichi, B.; Ascierto, P.A.; Garbe, C.; Robert, C.; Schadendorf, Dirk; Hauschild, A.

  Neoadjuvant intralesional targeted immunocytokines (daromun) in stage III melanoma

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• Fizazi, K.; Chi, K.N.; Shore, N.D.; Herrmann, Ken; de Bono, J.S.; Castellano, D.; Piulats, J.M.; Fléchon, A.; Wei, X.X.; Mahammedi, H.; Roubaud, G.; Fleming, M.; Haas, T.; Ghebremariam, S.; Kreisl, T.N.; Rajagopalan, S.; Sartor, O.; Morris, M.J.

  Final overall survival and safety analyses of the phase III PSMAfore trial of [¹⁷⁷Lu]Lu-PSMA-617 versus change of androgen receptor pathway inhibitor in taxane-naive patients with metastatic castration-resistant prostate cancer

  In: Annals of Oncology, Vol. 36, 2025, Nr. 11, pp. 1319 – 1330

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• Schetelig, Johannes; Baldauf, Henning; Rave, Carina; Bug, Gesine; Müller, Lutz P.; Wagner-Drouet, Eva Maria; Ayuk, Francis Ayuketang; Bethge, Wolfgang; Stelljes, Matthias; Schroeder, Thomas; Stölzel, Friedrich; Jost, Edgar; Schmid, Christoph; Kunadt, Desiree; Sockel, Katja; Egger-Heidrich, Katharina; Middeke, Jan Moritz; Fürst, Daniel; Schefzyk, Daniel; Sauter, Jürgen; Schmidt, Alexander H.; Fleischhauer, Katharina; Bornhäuser, Martin

  Young unrelated donors confer a survival advantage for patients with myeloid malignancies compared to older siblings

  In: Leukemia, Vol. 39, 2025, Nr. 10, pp. 2523 – 2532

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• Hesterberg, Rebecca S.; Davis, Joshua T.; Handoo, Komal J.; Elmarsafawi, Aya G.; Augello, Anthony C.; Cheng, Chia-Ho; Atkins, Reginald; Lee, Dae Hyun; Yang, Chunying; Yao, Jiqiang; Patel, Krishna R.; Mediavilla-Varela, Melanie; Pinilla-Ibarz, Javier; Soto-Palma, Carolina; Locke, Frederick L.; Song, Xiaofei; Wang, Xuefeng; Berglund, Anders E.; Rodriguez, Paulo C.; Knittel, Gero; Flümann, Ruth; Reinhardt, Hans Christian; Shaw, Timothy I.; Yu, Xiaoqing; Niedernhofer, Laura J.; Cleveland, John L.

  Lymphoma accelerates T cell and tissue aging

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  Unraveling Relatlimab-Specific Biology Using Biomarker Analyses in Patients with Advanced Melanoma in RELATIVITY-047

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  Functional synapses between neurons and small cell lung cancer

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  Fulminant myocarditis : outcome predictors in an international cohort study

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  ATXN3 regulates lysosome regeneration after damage by targeting K48-K63-branched ubiquitin chains

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  Selective inhibition of mitochondrial Kv1.3 prevents and alleviates multiple sclerosis in vivo

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  TXNIP mediates LAT1/SLC7A5 endocytosis to limit amino acid uptake in cells entering quiescence

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  Transcription factor switching drives subtype-specific pancreatic cancer

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  Adjuvant nivolumab and relatlimab in stage III/IV melanoma : the randomized phase 3 RELATIVITY-098 trial

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  Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis

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  Mitochondrial Glutathione Import Enables Breast Cancer Metastasis via Integrated Stress Response Signaling

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  Cutaneous melanoma : ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

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