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Collaborative Research Centre 1093:

Supramolecular Chemistry on Proteins

Protein function is intimately connected with supramolecular chemistry: Substrate processing and various levels of regulation involve specific noncovalent interactions. Likewise, protein folding, assembly and protein-protein interactions are governed by intermolecular forces and their specific inhibition or support represents a very promising area for external interference, with profound mechanistic and therapeutic implications.

The CRC aims at applying recent knowledge and methods from supramolecular chemistry to achieve specific interaction with proteins by artificial ligands.

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New CRC1093 Associated Member

Professor Jens Voskuhl joins the CRC1093

Jens Voskuhl has been appointed as a Juniorprofessor at the Faculty of Chemistry recently and will start now to collaborate with several groups within the CRC as an associated member.

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Determinants of amyloid fibril degradation by the PDZ protease HTRA1

S. Poepsel, A. Sprengel, B. Sacca, F. Kaschani , M. Kaiser, C. Gatsogiannis, S. Raunser, T. Clausen and M. Ehrmann: Determinants of amyloid fibril degradation by the PDZ protease HTRA1.

Nature Chemical Biology. 2015, doi:10.1038/nchembio.1931

"PLUS3" Grant from the Boehringer Ingelheim Foundation

CRC1093 Principal Investigator Dr. Elsa Sánchez-García received the prestigious “PLUS3” grant from the Boehringer Ingelheim Foundation. This programme supports her project focusing on the computational design of molecules with therapeutic potential. Read more

CRC1093 Workshop

Drug Discovery and its Challenges

The drug discovery workshop provides insight into applied research in the pharmaceutical industry from target identification to clinical studies and emphasises the challenges of classical and modern screening methods. The workshop is a full day seminar with some short introductory lectures given by Oliver von Ahsen and literature talks that should be prepared and presented by the students in teams of two.

Lecturer: Oliver von Ahsen (Global Drug Discovery - Bayer Pharma AG, Berlin)

Saturday, 12th of March 2016  Programme

1st International Symposium 2015

Supramolecular Chemistry on Proteins

Crc1093 International Symposium 2015 1500 X 700

We thank all speakers and participants for this successful and inspiring symposium!

Crafting Your Science Career

Aspire Afternoon 2015

[07.07.15] Ina Krebs, Dr. Nicolette and Dr. Petra Rzepecki were invited to join our Aspire Afternoon 2015 and talk to PhD students about their work, their own career path, reconciliation of family and work life and future opportunities in industry and business.

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News

Embo Short-Term Fellowship for CRC1093 Postdoc

[30.05.15] Johannes van den Boom was awarded with one of the internationally sought-after “Embo Short-Term Fellowships”. Supported by this fellowship the postdoc spent three month at the renowned Rockefeller University in New York.

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