Selected Publications

2019

2018

A mass spectrometry-based profiling of
interactomes of viral DDB1- and cullin
ubiquitin ligase-binding proteins reveals
NF-κB inhibitory activity of the HIV-2-encoded Vpx

Landsberg CD, Megger DA, Hotter D, Rückborn MU, Eilbrecht M, Rashidi-Alavijeh J, Howe S, Heinrichs S, Sauter D, Sitek B, Le-Trilling VTK, Trilling M. A mass spectrometry-based profiling [...] Front Immunol. 2018 Dec 19;9:2978.

CEACAM1 promotes CD8+ T cell
responses and improves control
of a chronic viral infection

Khairnar V, et al. CEACAM1 promotes CD8+ T cell responses [...] Nat Commun. 2018 Jul 2;9(1):2561. doi: 10.1038/s41467-018-04832-2.

2017

Sphingosine 1-phosphate- and C-C
chemokine receptor 2-dependent activation
of CD4+ plasmacytoid dendritic cells
in the bone marrow contributes to signs
of sepsis-induced immunosuppression

Smirnov A, et al. Sphingosine 1-phosphate- and CCR2-dependent activation [...] Front. Immunol. 2017 Nov 23; doi.org/10.3389/fimmu.2017.01622.

Conventional CD11chigh dendritic cells are important for T cell priming during the initial phase of Plasmodium yoelii infection,
but are dispensable at later time points

Ueffing K, Abberger H, Westendorf AM, Matuschewski K, Buer J, Hansen W. Conventional CD11chigh dendritic cells are important for T cell priming [...]. Front Immunol. 2017 Oct 16; 8:1333. doi: 10.3389/fimmu.2017.01333. eCollection 2017.

Deciphering of the human interferon-regulated proteome by mass spectrometry-based quantitative analysis reveals extent and dynamics of protein induction
and repression

Megger DA, Philipp J, Khanh Le-Trilling VT, Sitek B, and Trilling M. Deciphering of the human interferon-regulated proteome [...]. Front. Immunol. 2017 Sep 14; 8:1139. doi: 10.3389/fimmu.2017.01139.

DC-derived IL-10 modulates pro-inflammatory cytokine production
and promotes induction of CD4+IL-10+
regulatory T cells during Plasmodium yoelii infection

Loevenich K, Ueffing K, Abel S, Hose M, Matuschewski K, Westendorf AM, Buer J, and Hansen W. DC-derived IL-10 modulates pro-inflammatory [...]. Front. Immunol. 2017 Feb 28; 8:152. doi: 10.3389/fimmu.2017.00152.

2016

Combination of nanoparticle-based
therapeutic vaccination and transient
ablation of regulatory T cells enhances
anti-viral immunity during chronic
retroviral infection

Knuschke T, et al. Combination of nanoparticle-based therapeutic vaccination [...]. Retrovirology. 2016 Apr 14;13(1):24. doi: 10.1186/s12977-016-0258-9.

2015

Modified vaccinia virus Ankara-infected
dendritic cells present CD4+ T-cell epitopes by endogenous major histocompatibility complex class II presentation pathways

Thiele F, Tao S, Zhang Y, Muschaweckh A, Zollmann T, Protzer U, Abele R, Drexler I. Modified vaccinia virus Ankara-infected dendritic cells [...]. J Virol. 2015 Mar; 89(5):2698-709. doi: 10.1128/JVI.03244-14.

Contact

Research Training Group 1949
Immune Response in
Infectious Diseases -
Regulation between Innate
and Adaptive Immunity

Spokesperson:
Prof. Dr. Astrid Westendorf

Deputy: Prof. Dr. Jörg Timm
Deputy: Prof. Dr. Mirko Trilling

Coordination: Daniela Catrini

Phone: +49 201 723 35 88
E-Mail: daniela.catrini@uni-due.de