Publications

2026

    Journal articles

  • Haase, Max A. B.; Lazar-Stefanita, Luciana; Baudry, Lyam; Wudzinska, Aleksandra; Zhou, Xiaofan; Rokas, Antonis; Hittinger, Chris Todd; Pfander, Boris; Musacchio, Andrea; Boeke, Jef D.
    Ancient co-option of LTR retrotransposons as yeast centromeres
    In: Nature, 2026, in press
    DOI (Open Access)
  • Eberle, Julia; Salem, Ahmed; Hofmann, Mara; Reisser, Anja; Ruiz-Blanco, Yasser B.; Almeida-Hernandez, Yasser; Gole, Boris; Rall-Scharpf, Melanie; Angulo-Capel, Jessica; Monecke, Thomas; Sanchez-Garcia, Elsa; Gebhardt, J Christof M; Wiesmüller, Lisa
    Discovery of an Endonuclease G-inhibitory Ku80-peptide protecting against leukemogenic rearrangements at the MLL breakpoint cluster
    In: Nature Communications, Vol. 17, 2026, Nr. 1, 3562
    DOI (Open Access)
  • Walstein, Kai; Hill, Louisa; Vogt, Doro; Oberste-Lehn, Lina; Janning, Petra; Vetter, Ingrid R; Pan, Dongqing; Musacchio, Andrea
    M18BP1 valency and a distributed interaction footprint determine epigenetic centromere specification in humans
    In: The EMBO Journal, 2026, in press
    DOI (Open Access)
  • Pleuger, Richard; Westermann, Stefan
    Mitotic error correction and the spindle assembly checkpoint : a tension-filled relationship
    In: Cell Cycle, Vol. 25, 2026, Nr. 1, pp. 1 – 19
    DOI (Open Access)
  • Esposito-Verza, Arianna; Conti, Duccio; Rodrigues Pedroso, Paulo D.; Oberste-Lehn, Lina; Koerner, Carolin; Wohlgemuth, Sabine; Mansurkhodzhaev, Artem; Vetter, Ingrid R.; Pesenti, Marion E.; Musacchio, Andrea
    Molecular requirements for PLK1 activation by T-loop phosphorylation
    In: The EMBO Journal, Vol. 45, 2026, Nr. 5, pp. 1496 – 1536
    DOI (Open Access)
  • Simon, Gina; Abraham Pol, Savina; Dendusic, Melisa; Schulze, Nina; Stupia, Simone; Koci, Michelle; Buzuk, Lana; Thier, Beatrice; Steinbach, Philine; Trinh, Hai; Schillinger, Jasmin; Ninck, Sabrina; Kaschani, Farnusch; Kaiser, Markus; Ehrmann, Michael; Paschen, Annette; Hellerschmied, Doris
    Stress-induced proteome remodeling at the Golgi-endosome interface
    In: Journal of Cell Science, 2026, in press
    DOI (Open Access)
  • Klink, Nikolas; Urban, Sebastian; Seier, Johanna A.; Adhikari, Bikash; Schwalm, Martin P.; Müller, Juliane; Dorsch, Madeleine; Steinbach, Philine; Jung, Jennifer; Vogt, Markus; Kaschani, Farnusch; Koch, Johannes; Führer, Siska; Kaiser, Markus; Schulze, Nina; Knapp, Stefan; Wolf, Elmar; Paschen, Annette; Grüner, Barbara M.; Gersch, Malte
    Targeted degradation of USP7 in solid cancer cells reveals distinct effects of deubiquitinase degraders and inhibitors
    In: Nature Communications, Vol. 17, 2026, Nr. 1, 4331
    DOI (Open Access)

    • Preprints

  • Diamantino, Joao; Murteira, Sofia; Lawo, Steffen; Kaschani, Farnusch; Kaiser, Markus; Hellerschmied, Doris
    Selective proteasomal degradation from the Golgi apparatus membrane
    2026
    DOI (Open Access)

2025

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2024

Error in source processing

2023

    Journal articles

  • Patwardhan, Rutuja; Nanda, Suchet; Wagner, Jessica; Stockter, Tom; Dehmelt, Leif; Nalbant, Perihan; Li, Rong (Eds.)
    Cdc42 activity in the trailing edge is required for persistent directional migration of keratinocytes
    In: Molecular Biology of the Cell, Vol. 35, 2023, Nr. 1, br1
    DOI, Online Full Text (Open Access)
  • Hoi, David M.; Junker, Sabryna; Junk, Lukas; Schwechel, Kristin; Fischel, Katharina; Podlesainski, David; Hawkins, Paige M.E.; van Geelen, Lasse; Kaschani, Farnusch; Leodolter, Julia; Morreale, Francesca Ester; Kleine, Stefan; Guha, Somraj; Rumpel, Klaus; Schmiedel, Volker M.; Weinstabl, Harald; Meinhart, Anton; Payne, Richard J.; Kaiser, Markus; Hartl, Markus; Boehmelt, Guido; Kazmaier, Uli; Kalscheuer, Rainer; Clausen, Tim
    Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival
    In: Cell, Vol. 186, 2023, Nr. 10, pp. 2176 – 2192.e22
    DOI (Open Access)
  • Flümann, Ruth; Hansen, Julia; Pelzer, Benedikt W.; Nieper, Pascal; Lohmann, Tim; Kisis, Ilmars; Riet, Tobias; Kohlhas, Viktoria; Nguyen, Phuong-Hien; Peifer, Martin; Abedpour, Nima; Bosco, Graziella; Thomas, Roman K.; Kochanek, Moritz; Knüfer, Jacqueline; Jonigkeit, Lorenz; Beleggia, Filippo; Holzem, Alessandra; Büttner, Reinhard; Lohneis, Philipp; Meinel, Jörn; Ortmann, Monika; Persigehl, Thorsten; Hallek, Michael; Calado, Dinis Pedro; Chmielewski, Markus; Klein, Sebastian; Göthert, Joachim R.; Chapuy, Bjoern; Zevnik, Branko; Wunderlich, F. Thomas; von Tresckow, Bastian; Jachimowicz, Ron D.; Melnick, Ari M.; Reinhardt, Hans Christian; Knittel, Gero
    Distinct genetically-determined origins of Myd88/Bcl2-driven aggressive lymphoma rationalize targeted therapeutic intervention strategies
    In: Blood Cancer Discovery, Vol. 4, 2023, Nr. 1, pp. 78 – 97
    DOI (Open Access)
  • Fehr, Lorenz; Sewald, Leonard; Huber, Robert; Kaiser, Markus
    Facile Multicomponent Synthesis of Oxazolidinones from Primary Amines and Cesium (Hydrogen)Carbonate
    In: European Journal of Organic Chemistry, Vol. 26, 2023, Nr. 27, e202300135
    DOI (Open Access)
  • Stupia, Simone; Heeke, Christina; Brüggemann, Alicia; Zaremba-Montenari, Anne; Thier, Beatrice; Kretz, Julia; Sucker, Antje; Philip, Manuel; Zelinskyy, Gennadiy; Ferrone, Soldano; Rösch, Alexander; Horn, Susanne; Hadaschik, Eva; Schadendorf, Dirk; Trilling, Mirko; Dittmer, Ulf; Griewank, Klaus; Zhao, Fang; Paschen, Annette
    HLA class II loss and JAK1/2 deficiency coevolve in melanoma leading to CD4 T cell and IFNγ cross-resistance
    In: Clinical Cancer Research, Vol. 29, 2023, Nr. 15, pp. 2894 – 2907
    DOI
  • Váraljai, Renáta; Zimmer, Lisa; Al-Matary, Yahya; Kaptein, Paulien; Albrecht, Lea J.; Shannan, Batool; Brase, Jan C.; Gusenleitner, Daniel; Amaral, Teresa; Wyss, Nina; Utikal, Jochen; Flatz, Lukas; Rambow, Florian; Reinhardt, Hans Christian; Dick, Jenny; Engel, Daniel R.; Horn, Susanne; Ugurel, Selma; Sondermann, Wiebke; Livingstone, Elisabeth; Sucker, Antje; Paschen, Annette; Zhao, Fang; Placke, Jan-Malte; Klose, Jasmin M.; Fendler, Wolfgang; Thommen, Daniela S.; Helfrich, Iris; Schadendorf, Dirk; Rösch, Alexander
    Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma
    In: Nature Cancer, Vol. 4, 2023, Nr. 9, pp. 1292 – 1308
    DOI (Open Access)
  • O’Dea, Rachel; Kazi, Nafizul; Hoffmann-Benito, Alicia; Zhao, Zhou; Recknagel, Sarah; Wendrich, Kim; Janning, Petra; Gersch, Malte
    Molecular basis for ubiquitin/Fubi cross-reactivity in USP16 and USP36
    In: Nature Chemical Biology, Vol. 19, 2023, Nr. 11, pp. 1394 – 1405
    DOI (Open Access)
  • Zhao, Zhou; O’Dea, Rachel; Wendrich, Kim; Kazi, Nafizul; Gersch, Malte
    Native Semisynthesis of Isopeptide-Linked Substrates for Specificity Analysis of Deubiquitinases and Ubl Proteases
    In: Journal of the American Chemical Society: JACS, Vol. 145, 2023, Nr. 38, pp. 20801 – 20812
    DOI (Open Access)
  • Cmentowski, Verena; Ciossani, Giuseppe; d'Amico, Ennio; Wohlgemuth, Sabine; Owa, Mikito; Dynlacht, Brian; Musacchio, Andrea
    RZZ‐Spindly and CENP‐E form an integrated platform to recruit dynein to the kinetochore corona
    In: The EMBO Journal, Vol. 42, 2023, Nr. 24, e114838
    DOI (Open Access)
  • Nanda, Suchet; Calderon, Abram; Sachan, Arya; Duong, Thanh-Thuy; Koch, Johannes; Xin, Xiaoyi; Solouk-Stahlberg, Djamschid; Wu, Yao-Wen; Nalbant, Perihan; Dehmelt, Leif
    Rho GTPase activity crosstalk mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cycles
    In: Nature Communications, Vol. 14, 2023, Nr. 1, 8356
    DOI (Open Access)
  • van den Boom, Johannes; Marini, Guendalina; Meyer, Hemmo; Saibil, Helen R
    Structural basis of ubiquitin-independent PP1 complex disassembly by p97
    In: The EMBO Journal, Vol. 42, 2023, Nr. 14, e113110
    DOI (Open Access)
  • Rüttermann, Maximilian; Koci, Michelle; Lill, Pascal; Geladas, Ermis Dionysios; Kaschani, Farnusch; Klink, Björn Udo; Erdmann, Ralf; Gatsogiannis, Christos
    Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate
    In: Nature Communications, Vol. 14, 2023, Nr. 1, 5942
    DOI (Open Access)
  • Kornakov, Nikolay; Westermann, Stefan
    Systematic analysis of microtubule plus-end networks defines EB-cargo complexes critical for mitosis in budding yeast
    In: Molecular Biology of the Cell, Vol. 34, 2023, Nr. 5, ar37
    DOI, Online Full Text (Open Access)
  • Meyer, Hemmo; van den Boom, Johannes
    Targeting of client proteins to the VCP/p97/Cdc48 unfolding machine
    In: Frontiers in Molecular Biosciences, Vol. 10, 2023, 1142989
    DOI, Online Full Text (Open Access)
  • Blüggel, Mike; Kröning, Alexander; Kracht, Matthias; van den Boom, Johannes; Dabisch, Matthias; Göhring, Anna; Kaschani, Farnusch; Kaiser, Markus; Bayer, Peter; Meyer, Hemmo; Beuck, Christine
    The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPase
    In: Nature Communications, Vol. 14, 2023, Nr. 1, 3258
    DOI, Online Full Text (Open Access)
  • Schwalm, Martin P.; Krämer, Andreas; Dölle, Anja; Weckesser, Janik; Yu, Xufen; Jin, Jian; Saxena, Krishna; Knapp, Stefan
    Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization
    In: Cell Chemical Biology, Vol. 30, 2023, Nr. 7, pp. 753 – 765.e8
    DOI, Online Full Text (Open Access)
  • Buzuk, Lana; Hellerschmied-Jelinek, Doris
    Ubiquitin-mediated degradation at the Golgi apparatus
    In: Frontiers in Molecular Biosciences, Vol. 10, 2023, 1197921
    DOI, Online Full Text (Open Access)

    • Prefaces/Postfaces

  • Venturutti, Leandro; Rivas, Martin A.; Pelzer, Benedikt W.; Flümann, Ruth; Hansen, Julia; Karagiannidis, Ioannis; Xia, Min; McNally, Dylan R.; Isshiki, Yusuke; Lytle, Andrew; Teater, Matt; Chin, Christopher R.; Meydan, Cem; Knittel, Gero; Ricker, Edd; Mason, Christopher E.; Ye, Xiaofei; Pan-Hammarström, Qiang; Steidl, Christian; Scott, David W.; Reinhardt, Hans Christian; Pernis, Alessandra B.; Béguelin, Wendy; Melnick, Ari M.
    An Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas
    In: Cancer Discovery. Philadelphia: American Association for Cancer Research (AACR), Vol. 13, 2023, Nr. 1, pp. 216 – 243
    DOI, Online Full Text (Open Access)

    • Preprints

  • Pleuger, Richard; Cozma, Christian; Hohoff, Simone; Denkhaus, Christian; Dudziak, Alexander; Kaschani, Farnusch; Musacchio, Andrea; Vetter, Ingrid R.; Westermann, Stefan
    Ipl1-controlled attachment maturation regulates Mps1 association with its kinetochore receptor
    2023
    DOI (Open Access)

    • Posters / Proceedings posters

  • Lama, Soni; Koch, Johannes; Schulze, Nina; Rehwald, Stephanie
    Sharing, storing and analysing cell image data in a Collaborative Research Centre using OMERO
    Data Steward goes Germany 2023, 25.-26.09.2023, Dresden,
    2023
    DOI (Open Access)

2022

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2021

    Journal articles

  • Böhm, Miriam; Killinger, Kerstin; Dudziak, Alexander; Pant, Pradeep; Jänen, Karolin; Hohoff, Simone; Mechtler, Karl; Örd, Mihkel; Loog, Mart; Sánchez-García, Elsa; Westermann, Stefan
    Cdc4 phospho-degrons allow differential regulation of ame1ceⁿp⁻u protein stability across the cell cycle
    In: eLife, Vol. 10, 2021, e67390
    DOI (Open Access)
  • Dudziak, Alexander; Engelhard, Lena; Bourque, Cole; Klink, Björn Udo; Rombaut, Pascaline; Kornakov, Nikolay; Jänen, Karolin; Herzog, Franz; Gatsogiannis, Christos; Westermann, Stefan
    Phospho-regulated Bim1/EB1 interactions trigger Dam1c ring assembly at the budding yeast outer kinetochore
    In: The EMBO Journal, Vol. 40, 2021, Nr. 18, e108004
    DOI (Open Access)
  • Dorsch, Madeleine; Kowalczyk, Manuela; Planque, Mélanie; Heilmann, Geronimo; Urban, Sebastian; Dujardin, Philip; Forster, Jan; Ueffing, Kristina; Nothdurft, Silke; Oeck, Sebastian; Paul, Annika; Liffers, Sven T.; Kaschani, Farnusch; Kaiser, Markus; Schramm, Alexander; Siveke, Jens T.; Winslow, Monte M.; Fendt, Sarah-Maria; Nalbant, Perihan; Grüner, Barbara M.
    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
    In: Cell Reports, Vol. 37, 2021, Nr. 8, 110056
    DOI, Online Full Text (Open Access)