Location

Essen

Application area

Faculty of Biology, Molecular Cell Biology

PhD Scientific Researcher, Faculty of Biology, Molecular Cell Biology (w/m/d, No. 598-25)
EG 13 TV-L

Project title:

Role of Rho GTPase proteins in signal networks in tumor related dynamic cell behavior

Project description:

Participation in the research project: “The role of Rho-GTPase proteins in the control of tumor-associated dynamic cell processes”

The project investigates the regulation of subcellular activity dynamics of actin-regulating Rho-GTPases and their role in dynamic cell processes, such as cell migration, invasion and cell division.

Start of employment

As soon as possible

Duration of employment

3 years

Working time

25 h 53 min (65 %)

Your main tasks

To work on the project, PhD candidates should pursue a multifaceted research program that includes the following approaches:

• Establishment and use of cell lines with fluorescently labelled Rho signaling network components
• Measurement of subcellular, dynamic Rho GTPase activity with fluorescent sensors
• Generation of tumour spheroids for tracking dynamic cell processes also in 3D
• Application of modern light microscopy techniques, such as TIRF-M, TIRF-SIM and confocal spinning disk microscopy.

Your profile

Completed scientific university degree in Molecular Cell Biology, Chemical Biology or related subjects of at least 8 semesters (standard period of study).

We are looking for highly motivated, team-oriented candidates with a strong interest in the molecular mechanisms controlling cellular functions and excellent scientific skills. Candidates should have solid practical experience in cell and molecular biology methods, biochemical approaches and modern microscopy techniques. In particular, knowledge in the application of TIRF and confocal live cell microscopy as well as quantitative image analysis is an advantage. A university degree (Master or equivalent) with a focus on cell biology or biochemistry is required.

We offer you

• Being part of a cutting-edge research project.
• A varied, versatile field of activity in a lively work area with international exchange.
• An interesting, responsible job with great creative potential, where you will get to know the diverse tasks and developments of research transfer and have contacts with almost all areas of the UDE.
• A discrimination-free working environment with respectful, appreciative cooperation.
• A pleasant working environment in a dynamic team.
• The possibility to obtain a PhD with the help of numerous support services.
• Family-friendly environment with provision of child care and advice on caring responsibilities.
• A wide range of further education and training opportunities
• Excellent public transport connections and free parking
• Attractive range of sport and health activities (University Sports).
• The possibility to work from home (Homeoffice).

Application deadline

2025-12-05

Code number

598-25

Application

Please submit your application (CV, motivation letter, copies of certificates, transcripts of records and contact information of 2 persons who could provide references) before the deadline by e-mail with the subject “Application - PhD position” and quoting the reference number 598-25 to: perihan.nalbant@uni-due.de.

Information about the job

For further information on the position please contact Perihan Nalbant.

Open minded

We are a young, innovative university located in the heart of the Ruhr metropolis. We pride ourselves in outstanding research and teaching, think in terms of opportunities rather than limitations and develop ideas with a view to the future. Diversity is an integral part of our culture as we promote potential and are committed to upholding genuine equity in education.

Learn more

University of Duisburg-Essen pursues the goal of promoting the diversity of its members.
www.uni-due.de/diversity/en

In accordance with the State Equal Opportunities Act, women with the same qualifications are given preferential consideration.

Applications from suitable disabled persons and persons of equal status within the meaning of § 2 para. 3 SGB IX are desired.

By applying for one of the advertised positions, you expressly agree to the requirements in accordance with the General Data Protection Regulation and to being contacted by mail. Further information on data protection can be found here.

Back