Location

Essen

Application area

Centre for Medical Biotechnology (ZMB)

PhD position (f/m/d, No. 294-25)
EG 13 TV-L

The ZMB in Essen integrates medical research at the University Hospital and basic research at the Campus. The aim is to elucidate molecular mechanisms of diseases and to turn this knowledge into medical advances.

Start of employment

As soon as possible

Duration of employment

3 years

Working time

25 Std. 53 Min. (65 %)

Your main tasks

1 PhD position for “Cooperation of deubiquitinating enzymes and VCP/p97 in cellular stress responses” in the group of Prof. Dr. Hemmo Meyer.

The project aims to understand ubiquitin-mediated pathways regulating protein unfolding, degradation by the proteasome or autophagy with relevance for understanding aging, neurodegenerative disease or cancer vulnerabilities. The project will focus on biochemical reconstitution of complex cellular reactions from pure components for detailed understanding and modulation. Methods will include protein engineering and high-end functionalization, FRET analysis, biolayer interferometry, mass and "real-time" fluorescence spectroscopy as well as mutagenesis. Experimental extension to cell-based assays is an option.

Your profile

• The successful candidate will hold a Master in Biochemistry, Molecular Biology or related disciplines
• He/she has an excellent track record including experimental experience with protein purification and biochemical analysis.

We offer you

• Candidates will benefit from the international and interdisciplinary research environment at the ZMB, a structured graduate program and association with the Collaborative Research Center 1430
• a collaborative working atmosphere in a dynamic team
• state-of-the-art equipment and approaches
• a discrimination-free working environment with respectful, appreciative cooperation
• family-friendliness through childcare facilities for your children
• advice on family care responsibilities
• excellent public transport connections and free parking spaces
• attractive sports and health facilities (university sports)

Application deadline

2025-07-03

Code number

294-25

Application

Unfortunately, the application deadline has expired.

Information about the job

For more information please visit:

https://www.udue.de/meyer

https://www.uni-due.de/crc1430/

Open minded

We are a young, innovative university located in the heart of the Ruhr metropolis. We pride ourselves in outstanding research and teaching, think in terms of opportunities rather than limitations and develop ideas with a view to the future. Diversity is an integral part of our culture as we promote potential and are committed to upholding genuine equity in education.

Learn more

University of Duisburg-Essen pursues the goal of promoting the diversity of its members.
www.uni-due.de/diversity/en

In accordance with the State Equal Opportunities Act, women with the same qualifications are given preferential consideration.

Applications from suitable disabled persons and persons of equal status within the meaning of § 2 para. 3 SGB IX are desired.

By applying for one of the advertised positions, you expressly agree to the requirements in accordance with the General Data Protection Regulation and to being contacted by mail. Further information on data protection can be found here.

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