Biological Targets B3: Supramolecular specific inhibitors of intestinal proteases against ischemia/reperfusion in-jury

Dr. Michael Kirsch

Project B3 investigates the significance of specific digestive proteases and common hydrolases in ischemia/reperfusion injury of the small intestines. To this end, selective inhibitors for single digestive hydrolases will be developed by the chemists and probed within the pathogenetic network of the disease. The most specific and effective inhibitors will then be administered intraluminally in the rat small intestine. Biocompatibility, toxicity and effects on tissue regeneration of the inhibitors will be assessed. 

B3

Scientific Co-Workers

Name Phone E-Mail
Dr. Rabea Verhaegh +49 201 723 4104 Email
Lisa Brencher +49 201 723 4104 Email