CRC 1093 - Project B3
Biological Targets B3: Supramolecular specific inhibitors of intestinal proteases against ischemia/reperfusion in-jury
Dr. Michael Kirsch
Project B3 investigates the significance of specific digestive proteases and common hydrolases in ischemia/reperfusion injury of the small intestines. To this end, selective inhibitors for single digestive hydrolases will be developed by the chemists and probed within the pathogenetic network of the disease. The most specific and effective inhibitors will then be administered intraluminally in the rat small intestine. Biocompatibility, toxicity and effects on tissue regeneration of the inhibitors will be assessed.
Scientific Co-Workers
Name | Phone | |
---|---|---|
Dr. Rabea Verhaegh | +49 201 723 4104 | |
Lisa Brencher | +49 201 723 4104 |