Peer-reviewed publications

until 1999  

2000   2001   2002   2003  2004   2005   2006   2007   2008  2009  

2010   2011   2012   2013   2014   2015   2016   2017   2018   2019


Proceedings and Abstracts of Papers

Other Publications




Xin Liu, Kaiya Wang, Marlen Externbrink, Jochen Niemeyer, Michael Giese, Xiao-Yu Hu*,
Control of secondary structure and morphology of peptide–guanidiniocarbonylpyrrole conjugates by variation of the chain length, Chin. Chem. Lett., 2019, DOI: 10.1016/j.cclet.2019.10.036

D. Maity, K. I. Assaf, W. Sicking, C. Hirschhäuser*, W. M. Nau, C. Schmuck, A Selective Cucurbit[8]uril‐Peptide Beacon Ensemble for Ratiometric Fluorescence Detection of Peptides, Chem. Eur. J.2019, DOI: 10.1002/chem.201901037.

A. Gigante*, M. Li, S. Junghänel, C. Hirschhäuser, S. Knauer, C. Schmuck*, Non-viral transfection vectors: are hybrid materials the way forward?, MedChemComm, 2019, DOI: 10.1039/c9md00275h.

J. Hatai, C. Schmuck*, Diverse Properties of Guanidiniocarbonyl Pyrrole-Based Molecules: Artificial Analogues of Arginine, Acc. Chem. Res., 2019, 52, 6, 1709-1720, DOI:  10.1021/acs.accounts.9b00142.

D. Maity, A. Gigante, P. A. Sánchez-Murcia, E. Sijbesma, M. Li, D. Bier, S. Mosel, S. Knauer, C. Ottmann*, C. Schmuck*, Arginine mimetic appended peptide-based probes for fluorescence turn-on detection of 14-3-3 proteins, Org. Biomol. Chem., 2019, 17, 4359-4363, DOI: 10.1039/C9OB00620F.

A. Gigante, J. N. Grad, J. Briels, M. Bartel, D. Hoffmann*, C. Ottmann*, C. Schmuck*, A new class of supramolecular ligands stabilizes 14-3-3 protein–protein interactions by up to two orders of magnitude, Chem. Commun., 2019, 55, 111-114, DOI: 10.1039/C8CC07946C.

L. Bartsch, M. Bartel, J. I. Fernandez, Y. R. Blanco, C. Beuk, J. Briels, A. Gigante, N. Toetsch, P. Bayer, E. Sanchez-Garcia, C. Ottmann*, C. Schmuck, Multivalent ligands with tailor‐made anion binding motif as stabilizers of protein‐protein interactions, Chem. Bio. Chem., 2019, accepted, DOI: 10.1002/cbic.201900288.

J. Hatai, C. Schmuck, Artificial Peptide and Protein Receptors, Supramolecular Chemistry in water, Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim, 2019, 79-113, DOI: 10.1002/9783527814923.ch3.

J. Matić, F. Šupljika, T. Tandarić, M. Dukši, P. Piotrowski, R. Vianello, A. Brozovic, I. Piantanida, C. Schmuck, M. R. Stojković*, DNA/RNA recognition controlled by the glycine linker and the guanidine moiety of phenanthridine peptides, Int. J. Biol. Macromol., 2019, 134, 422-434, DOI: 10.1016/j.ijbiomac.2019.05.063.

H. Jiang, X.-Y. Hu, S. Mosel, S. K. Knauer, C. Hirschhäuser, C. Schmuck*, A Branched Tripeptide with an Anion-Binding Motif as a New Delivery Carrier for Efficient Gene Transfection, Chem. Bio. Chem., 2019, 20, 1410 –1416, DOI: 10.1002/cbic.201800728.

F. Filarsky*, C. Schmuck*, H. J. Schultz*, Development of a Gas Hydrate Absorption for Energy storage and Gas separation–Proof of Concept based on Natural Gas, Energy Procedia, 2019, 158, 5367–5373, DOI: 10.1016/j.egypro.2019.01.628.

F. Filarsky*, C. Schmuck, H. J. Schultz*, Development of a Surface-Active Coating for Promoted Gas Hydrate Formation, Chem. Ing. Tech., 2019, 91, 85–91, DOI: 10.1002/cite.201800002.




M. Externbrink, S. Riebe, C. Schmuck*, J. Voskuhl*; A Dual pH-Responsive Supramolecular Gelator with Aggregation-Induced Emission Properties. Soft Matter, 2018, 14, 6166-6170, DOI: 10.1039/C8SM01190G.

X.-Y. Hu*, M. Ehlers, T. Wang, E. Zellermann, S. Mosel, H. Jiang, J.-E. Ostwaldt, S. K. Knauer, L. Wang, C. Schmuck*, Formation of Twisted β-Sheet Tapes from a Self-Complementary Peptide Based on Novel Pillararene-GCP Host–Guest Interaction with Gene Transfection Properties. Chem. Eur. J., 2018, 24, 9754-9759, DOI:10.1002/chem.201801315.

H. Jiang, M. Ehlers, X.-Y. Hu, E. Zellermann, C. Schmuck*, Dimensional Control of Supramolecular Assemblies of Diacetylene-Derived Peptide Gemini Amphiphile: From Spherical Micelles to Foamlike Networks. Soft Matter, 2018, 14, 5565-5571; DOI: 10.1039/C8SM00512E.

M. Li, E. Zellermann, C. Schmuck*, Formation of Polymer Particles by Direct Polymerization on the Surface of a Supramolecular Template. Chem. Eur. J., 2018, 24, 9061-9065, DOI: 10.1002/chem.201705209.

F. Filarsky, C. Schmuck, H.-J. Schultz, Development of a Biogas Production and Purification Process using promoted Gas Hydrate Formation - A Feasibility Study, Chem. Eng. Res. Des. 2018, 134, 257-267; DOI: 10.1016/j.cherd.2018.04.009.

M. Li, S. Mosel, S. K. Knauer, C. Schmuck*, A dipeptide with enhanced anion binding affinity enables cell uptake and protein  delivery, OBC, 2018, 16, 2312-2317, DOI: 10.1039/C7OB02721D.

M. Ehlers, J.-N. Grad, S. Mittal, D. Bier, M. Mertel, L. Ohl, M. Bartel, J. Briels, M. Heimann, C. Ottmann, E. Sanchez-Garcia, D. Hoffmann, C. Schmuck*; Rational Design, Binding Studies, and Crystal Structure Evaluation oft he First Ligand Targeting the Dimerization Interface oft he 14-3-3Z Adapter Protein, ChemBioChem, 2018, 19, 591-595; DOI: 10.1002/cbic.201700588. (Very Important Paper)

J.-N. Grad, A. Gigante, C. Wilms, J. Dybowski, L. Ohl, C. Ottmann, C. Schmuck, D. Hoffmann*; Locating large flexible ligands on proteins, J. Chem. Info. Mod. 2018, 58, 315-327; DOI: 10.1021/acs.jcim.7b00413.

B. Zakeri, A. G. Martinéz, P. Sokkar, E. Sánchez-Garcia, C. Schmuck, S. Schlücker,* Molecular Recognition of the Protein Leucine Zipper by a Multivalent Supramolecular Ligand: Site-Specific, Sensitive and Label-free Probing by UV Resonance Raman Spectroscopy. PhysChemChemPhys 2018, 20, 1817-1820; DOI: 10.1039/c7p04971d.

K. Grossert, W. Sicking, E. Zellermann, C. Schmuck*; Hierarchical Self-Assembly of a Small Monomer with Two Orthogonal Binding Sites: From Discrete Hexagonal Containers to a Stimuli-Responsive Supramolecular Gel, Supra. Chem. 2018, 30, 395-403; DOI: 10.1080/10610278.2017.1392020.




Z. Ban, B. Zinic, R. Vianello, C. Schmuck, I. Piantanida*; Nucleobase - Guanidiniocarbonyl-pyrrole conjugates as novel fluorimetric sensors for single stranded RNA, Molecules 2017, 22, 2213-2235; DOI: 10.3390/molecules22122213.

K. Samanta, E. Zellermann, M. Zähres, C. Mayer, C. Schmuck*; A supramolecular inverted amphiphile and ist stepwise self-assembly into vesicular networks, Soft Matter 2017, 13, 8108 - 8112, DOI: 10.1039/C7SM01641G

D. Maity, M. Matkovic, S. Li, M. Ehlers, J. Wu, I. Piantanida,* C. Schmuck*; Peptide-based probes with tailor-made anion binding motif for direct fluorescence ‚switch-on‘ detection of nucleic acid in cells, Chem. Eur. J. 2017, 23, 17356-17362; DOI: 10.1002/chem.201703813.

H. Jiang, X.-Y. Hu, S. Schlesiger, M. Li, E. Zellermann, S. K. Knauer, C. Schmuck*; Morphology Dependent Cell Imaging by a Self-Assembled Diacetylene Peptide Amphiphile, Angew. Chem. Int. Ed. 2017, 56, 14526-14530; Angew. Chem. 2017, 129, 14718-14722; DOI: 10.1002/anie.201708168 bzw. DOI: 10.1002/ange.201708168.

S. Junghänel, S. Karczewski, S. Bäcker, S. K. Knauer, C. Schmuck*; A Systematic Structure Activity Study of a New Type of Small Peptidic Transfection Vectors Reveals the Importance of a Special Oxo-Anion Binding Motif for Gene Delivery; ChemBioChem 2017, 18, 2268-2279; DOI: 10.1002/cbic.201700433; Very Important Paper (VIP)

P. Jana, K. Samanta, E. Zellermann, C. Schmuck, S. Backer, S. Knauer, "Efficient Gene Transfection through Inhibition of β-Sheet (Amyloid Fiber) Formation of a Short Amphiphilic Peptide by Gold Nanoparticles." Angew. Chem. Int. Ed. Engl. 2017, DOI: 10.1002/anie.201700713.

W. Zhang, J. He, J. Wu, C. Schmuck, "In Vivo Detoxification of Lipopolysaccharide by Antimicrobial Peptides." Bioconjugate Chem. 2017, 28, 319-324.

D. Maity, M. Li, M. Ehlers, C. Schmuck, "A metal-free fluorescence turn-on molecular probe for detection of nucleoside triphosphates." Chem. Commun. 2017, 53, 208-211.

M. Li, M. Matkovic, I. Piantanida, C. Schmuck, "Incorporation of arginine mimetic residue into peptides for recognition of double stranded nucleic acid structure: Binding and aggregation studies." Bioorg. Med. Chem. 2017, 25, 1875-1880.

P. Jana, C. Schmuck, "Self-Assembly of a Tripodal Triszwitterion Forms a pH-Switchable Hydrogel that Can Reversibly Encapsulate Hydrophobic Guests in Water." Chem. Eur. J. 2017, 23, 320-326.





C. Schmuck, K. Samanta, M. Ehlers, "Two-Component self-assembly: Hierarchical formation of pH-switchable supramolecular networks by pi-pi induced aggregation of ion pairs." Chem. Eur. J. 2016, 22, 15242-15247.

K. Samanta, P. Jana, S. Baecker, S. Knauer, C. Schmuck, "Guanidiniocarbonyl pyrrole (GCP) conjugated PAMAM-G2, a highly efficient vector for gene delivery: the importance of DNA condensation." Chem. Commun. 2016, 12446-12449.

F. S. Merkel, C. Schmuck, H. J. Schultz, "Investigation of the Influence of Hydroxyl Groups on Gas Hydrate Formation at Pipeline-Like Conditions." Energy Fuels 2016, 30, 9141-9149.

J. Matic, F. Supljika, N. Tir, P. Piotrowski, C. Schmuck, M. Abramic, I. Piantanida, S. Tomic, "Guanidiniocarbonyl-pyrrole-aryl conjugates as inhibitors of human dipeptidyl peptidase III: combined experimental and computational study." RSC Adv. 2016, 6, 83044-83052.

D. Maity, C. Schmuck, "Fluorescent Peptide Beacons for the Selective Ratiometric Detection of Heparin." Chem. Eur. J. 2016, 22, 13156-13161.

D. Maity, J. Jiang, M. Ehlers, J. Wu, C. Schmuck, "A FRET-enabled molecular peptide beacon with a significant red shift for the ratiometric detection of nucleic acids." Chem. Commun. 2016, 52, 6134-6137.

M. Li, S. Schlesiger, S. K. Knauer, C. Schmuck, "Introduction of a tailor made anion receptor into the side chain of small peptides allows fine-tuning the thermodynamic signature of peptide-DNA binding." Org. Biomol. Chem. 2016, 14, 8800-8803.

M. Li, M. Radic Stojkovic, M. Ehlers, E. Zellermann, I. Piantanida, C. Schmuck, "Use of an Octapeptide-Guanidiniocarbonylpyrrole Conjugate for the Formation of a Supramolecular β-Helix that Self-Assembles into pH-Responsive Fibers." Angew. Chem., Int. Ed. 2016, 55, 13015-13018.

M. Li, M. Ethlers, S. Schlesiger, E. Zellermann, S. K. Knauer, C. Schmuck, "Incorporation of a Non-Natural Arginine Analogue into a Cyclic Peptide Leads to Formation of Positively Charged Nanofibers Capable of Gene Transfection." Angew. Chem. Int. Ed. 2016, 55, 598-601.

P. Jana, M. Ehlers, E. Zellermann, K. Samanta, C. Schmuck, "pH-Controlled Formation of a Stable β-Sheet and Amyloid-like Fibers from an Amphiphilic Peptide: The Importance of a Tailor-Made Binding Motif for Secondary Structure Formation." Angew. Chem., Int. Ed. 2016, 55, 15287-15291.





Y. Zou, Q. Wang, J. Wu, J. Wu, C. Schmuck, H. Tian, "Peptide self-assembly triggered by metal ions." Chem. Soc. Rev. 2015, 44, 5200-5219.

K. Samanta, C. Schmuck, "Two-component self-assembly of a tetra-guanidiniocarbonyl pyrrole cation and Na4EDTA: formation of pH switchable supramolecular networks." Chem. Commun. 2015, 16065-16067.                                

M. Radic Stojkovic, P. Piotrowski, C. Schmuck, I. Piantanida, "A short, rigid linker between pyrene and guanidiniocarbonyl-pyrrole induced a new set of spectroscopic responses to the ds-DNA secondary structure." Org. Biomol. Chem. 2015, 13, 1629-1633.

F. S. Merkel, C. Schmuck, H. J. Schultz, T. A. Scholz, S. Wolinski, "Research on gas hydrate plug formation under pipeline-like conditions." Int. J. Chem. Eng. 2015, 1-6.

D. Maity, C. Schmuck, "Synthetic Receptors for Amino Acids and Peptides." Monogr. Supramol. Chem. 2015, 14, 326-368.

M. Li, S. Schlesiger, S. K. Knauer, C. Schmuck, "A tailor-made specific anion-binding motif in the side chain transforms a tetrapeptide into an efficient vector for gene delivery." Angew. Chem., Int. Ed. 2015, 54, 2941-2944.

Q.-Q. Jiang, W. Sicking, M. Ehlers, C. Schmuck, "Discovery of potent inhibitors of human β-tryptase from pre-equilibrated dynamic combinatorial libraries." Chem. Sci. 2015, 6, 1792-1800.

S. Banerjee, C. Schmuck, "Formation of Hydrogen-Bonded Self-assembled Structures in Polar Solvents." Lect. Notes Chem. 2015, 87, 187-225.





Q. Wang, X. Shi, X. Zhu, M. Ehlers, J. Wu, C. Schmuck, "A fluorescent light-up probe as an inhibitor of intracellular β-tryptase." Chem. Commun.  2014, 50, 6120-6122.

H. H. Kinfe, P. T. Moshapo, F. L. Makolo, D. W. Gammon, M. Ehlers, C. Schmuck, "Preparation and antimalarial activity of a novel class of carbohydrate-derived, fused thiochromans." Eur. J. Med. Chem. 2014, 87, 197-202.

C. Guetz, R. Hovorka, C. Klein, Q.-Q. Jiang, C. Bannwarth, M. Engeser, C. Schmuck, W. Assenmacher, W. Mader, F. Topic, K. Rissanen, S. Grimme, A. Luetzen, "Enantiomerically Pure [M6L12] or [M12L24] Polyhedra from Flexible Bis(Pyridine) Ligands." Angew. Chem. Int. Ed. 2014, 53, 1693-1698.

L. Chen, J. Wu, C. Schmuck, H. Tian, "A switchable peptide sensor for real-time lysosomal tracking." Chem. Commun.  2014, 6443-6446.

M. Fleischer, C. Schmuck, "Transforming polyethylenimine into a pH-switchable hydrogel by additional supramolecular interactions." Chem. Commun.  2014, 10464-10467.





H. Y. Kuchelmeister, C. Schmuck, "Molecular recognition of oligopeptides and protein surfaces." Springer Ser. Chem. Sens. Biosens. 2013, 12, 67-84.

H. Y. Kuchelmeister, C. Schmuck, "Molecular recognition of nucleotides." Springer Ser. Chem. Sens. Biosens. 2013, 12, 53-65.

H. Y. Kuchelmeister, S. Karczewski, A. Gutschmidt, S. Knauer, C. Schmuck;* Utilizing Combinatorial Chemistry and Rational Design: Peptidic Tweezers with Nanomolar Affinity to DNA can be transformed into Efficient Vectors for Gene Delivery by Addition of a Lipophilic Tail. Angew. Chem. 2013, 125, 14266-14270, Angew. Chem. Int. Ed. 2013, 52,14016-14020; DOI: 10.1002/anie.201306929.

Y. Hisamatsu, S. Banerjee, M. B. Avinash, T. Govindaraju, C. Schmuck;* A Supramolecular Gel from a Quadruple Zwitterion that Responds to Both Acid and Base. Angew. Chem. 2013, 125, 12782-12786, Angew. Chem. Int. Ed. 2013, 52,12550-12554; DOI: 10.1002/anie.201306986.

C. Gebner, S. Niebling, C. Schmuck, S. Schlücker, B. Engels;* Force field based conformational searches: efficiency and performance for peptide receptors complexes. Mol. Phys. 2013, 111, 2489-2500; DOI: 10.1080/00268976.2013.826392.

M. T. Fenske, W. Meyer-Zaika, H.-G. Korth, H. Vieker, A. Turchanin, C. Schmuck*; Cooperative Self-Assembly of Discoid Dimers: Hierarchical Formation of Nanostructures with a pH Switch. J. Am. Chem. Soc. 2013, 135, 8342-8349; DOI: 10.1021/ja4025148.

Q.-Q. Jiang, L. Bartsch, W. Sicking, P. R. Wich, D. Heider, D. Hoffmann, C. Schmuck*; A New Approach to Inhibit Human β-Tryptase by Protein Surface Binding of Four-Armed Peptide Ligands with Two Different Sets of Arms. Org. Biomol. Chem. 2013, 11, 1631-1639; DOI: 10.1039/C3OB27302D.

T. Gersthagen, J. Hofmann, F.-G. Klärner, C. Schmuck*, T. Schrader*; Ditopic Arginine-Aspartate Binders Recognize RGD Loops. Eur. J. Org. Chem. 2013, 1080-1092; DOI: 10.1002/ejoc.201201052.





M. B. Avinash, E. Verheggen, C. Schmuck*, T. Govindaraju*; Self-Cleaning Functional Molecular Materials. Angew. Chem. Int. Ed. 2012, 51, 10324 – 10328; DOI: 10.1002/anie.201204608.

S. Niebling, H. Y. Kuchelmeister, C. Schmuck, S. Schlücker*; Quantitative label-free monitoring of peptide recognition by artificial receptors: A comparative FT-IR and UV resonance Raman spectroscopic study. Chem. Sci. 2012, 3, 3371-3377; DOI: 10.1039/C2SC20811C.

W. Sicking, H. Somnitz, C. Schmuck*; DFT Calculations Suggest a New Type of Self-Protection and Self-Inhibition Mechanism in the Mammalian Heme Enzyme Myeloperoxidase: Nucleophilic Addition of a Functional Water rather than One-Electron Reduction. Chem. Eur. J. 2012, 18, 10937-10948, DOI: 10.1002/chem.201103477.

D. Hagmeyer, J. Ruesing, T. Fenske, H.-W. Klein, C. Schmuck, W. Schrader, M. E. Minas da Piedade, M. Epple*; Direct experimental observation of the aggregation of -amino acids into 100-200 nm clusters in aqueous solution. RCS Advances, 2012, 2, 4690-4696; DOI: 10.1039/C2RA01352E.

C. Schmuck, M. Merschky, C. Rether, B. Geibel (2012). Artificial Enzyme Mimics in Supramolecular Chemistry: from Molecules to Nanomaterials, J.W. Steed and P.A. Gale (eds). John Wiley & Sons Ltd, Chichester, UK, pp 1447-1496.

H. Y. Kuchelmeister, A. Gutschmidt, S. Knauer, C. Schmuck*; Efficient Gene Delivery into Cells by a Surprisingly Small Three-Armed Peptide Ligand. Chem. Sci. 2012, 3, 996-1002 (back cover); DOI:10.1039/C2SC01002J.

J. Wu, Y. Zou, W. Sicking, I. Piantanida, T. Yi*, C. Schmuck*; A Molecular Peptide Beacon for the Ratiometric Sensing of Nucleic Acids. J. Am. Chem. Soc. 2012, 134, 1958-1961; DOI:10.1021/ja2103845

T. H. Rehm, F. Gröhn, C. Schmuck*, Self-Assembly of a Triple-Zwitterion in Polar Solutions. Soft Matter, 2012, 8, 3154-3162; DOI:10.1039/C2SM07153C.

K. Klemm, M. R. Stojkovi , G. Horvat, V. Tomiši , I. Piantanida,* C. Schmuck*; Interactions of multicationic bis-guanidiniocarbonyl pyrrole receptors with double stranded nucleic acids: syntheses, binding studies and atomic force microscopy imaging. Chem. Eur. J. 2012, 18, 1352-1363; DOI: 10.1002/chem.201101544.

T. Fenske, H.-G. Korth, A. Mohr, C. Schmuck*; Advances in switchable supramolecular nanoassemblies. Chem. Eur. J. 2012, 18, 738-755; DOI: 10.1002/chem.201102435.





M. Gellner, S. Niebling, H. Y. Kuchelmeister, C. Schmuck, S. Schlücker*; Plasmonically active micron-sized beads for integrated solid-phase synthesis and label-free SERS analysis. Chem.Commun. 2011, 47, 12762-12764; DOI: 10.1039/c1cc13562g.

S. Langolf, U. Machon, M. Ehlers, W. Sicking, T. Schirmeister,* C. Büchhold, C. Gelhaus, P. J. Rosenthal, C. Schmuck*; Development of Novel Antitrypanosomal and Antiplasmodial Nonpeptidic Cysteine Protease Inhibitors on the Basis of N-protected-Guanidino-Furan and -Pyrrole Building Blocks. Chem.Med.Chem. 2011, 6, 1581-1586; DOI: 10.1002/cmdc.201100189

C. Schmuck; A journey through twelve years of interacting molecules: from artificial amino acid receptors to the recognition of biomolecules and switchable nanomaterials. Synlett 2011, 1798-1815; DOI: 10.1055/s-0030-1260946 (invited account).

N. Müller-Sienerth, L. Dietz, P. Holtz, D. Siegmund, M. Kapp, G. U. Grigoleit, C. Schmuck, H. Wajant*; SMAC mimetic BV6 induces cell death in monocytes and maturation of monocyte-derived dendritic cells. PLoS ONE, 2011, 6, e21556; DOI: 10.1371/journal.pone.0021556.

C. Rether, E. Verheggen, C. Schmuck; Unexpected stable dimerisation of an anionic imido pyrrolecarboxylate in polar solution. ChemCommun 2011, 47, 9078-9079; DOI: 10.1039/C1CC13446A.

J. Wu, A. Zawistowski, M. Ehrmann, T. Yi, C. Schmuck*; Peptide functionalized Polydiacetylene Liposomes act as a Fluorescent Turn-On Sensor for Bacterial Lipopolysaccharide. J. Am. Chem. Soc. 2011, 133, 9720–9723; DOI: 10.1021/ja204013u (highlighted in Chemical & Engineering News, June 2, 2011)

G. Gröger, W. Meyer-Zaika, C. Böttcher, F. Gröhn,* C. Ruthard, C. Schmuck*; Switchable supramolecular polymers from the self-assembly of a small monomer with two orthogonal binding interactions. J. Am. Chem. Soc. 2011, 133, 8961–8971; DOI: 10.1021/ja200941a.

F. Rodler, W. Sicking, C. Schmuck*; Stereoselective self-sorting in the self-assembly of a Phe-Phe extended guanidiniocarbonyl pyrrole carboxylate zwitterion: Formation of two diastereomeric dimers with significantly different stabilities. Chem. Commun. 2011, 47, 7953-7955; DOI: 10.1039/C1CC12520F.

C. Schmuck; Robust materials from weak forces. (News & Views article) Nature Nanotech. 2011, 6, 136-137.

H. Y. Kuchelmeister, C. Schmuck*; Nucleotide Recognition in Water by a Guanidinium-Based Artificial Tweezer Receptor. Chem. Eur. J. 2011, 17, 5311-5318; DOI: 10.1002/chem.201003393.

B. Geibel, M. Merschky, C. Rether, C. Schmuck*; Artificial Enzyme Mimics; invited contribution to Supramolecular Chemistry: From Molecules to Nanomaterials (edited by P. A. Gale, J. W. Steed), Wiley-VCH, in press.

C. Rether, C. Schmuck;* Carboxylate binding by indole based guanidinium receptors: A case study showing that apparently identical affinities of binding sites in different receptors can be due to quite different thermodynamic reasons. Eur. J. Org. Chem. 2011, 1459–1466; DOI: 10.1002/ejoc.201001465.

H. Y. Kuchelmeister, C. Schmuck;* Guanidinium Based Anion Receptors in Artificial Receptors for Chemical Sensors (Editors Mirsky, Yatsimirsky), Wiley-VCH, 2011, ISBN: 978-3-527-32357-9.

K. Gröger, D. Bareti , I. Piantanida,* M. Marjanovi , M. Kralj, M. Grabar, S. Tomi , C. Schmuck*; Guanidiniocarbonyl-pyrrole-aryl conjugates as nucleic acid sensors: switch of binding mode and spectroscopic responses by introducing additional binding sites into the linker. Org. Biomol. Chem. 2011, 9, 198-209; DOI:10.1039/C0OB00103A.

S. Niebling, H. Y. Kuchelmeister, C. Schmuck, S. Schlücker*; Quantitative, label-free and site-specific monitoring of molecular recognition: A multivariate resonance Raman approach. Chem. Commun. 2011, 47, 568-570; DOI: 10.1039/C0CC02052D.





M. Merschky, M. Wyszogrodzka, R. Haag, C. Schmuck*; pH Triggered Self-Assembly of Zwitterionic Polyglycerol Dendrons into Discrete and Highly Stable Supramolecular Dendrimers in Water. Chem. Eur. J. 2010, 16, 14242-14246; DOI: 10.1002/chem.201002658.

F. Rodler, J. Linders, T. Fenske, T. Rehm, C. Mayer, C. Schmuck*; Acid/base-switchable vesicles from a serine-derived zwitterionic guanidiniocarbonyl pyrrole carboxylate. Angew. Chem. 2010, 122, 8929-8932; Angew. Chem. Int. Ed. 2010, 49, 8747-8750; DOI: 10.1002/anie.201003405.

C. Urban, C. Schmuck; Active transport of amino acids by a guanidiniocarbonyl-pyrrole receptor. Chem. Eur. J. 2010, 16, 9502-9510; DOI: 10.1002/chem.201000509.

J. Voskuhl, T. Fenske, M. C. A. Stuart, B. Wibbeling, C. Schmuck,* B. J. Ravoo;* Molecular Recognition of Vesicles: Host Guest Interaction Combined with Specific Dimerization of Zwitterions. Chem. Eur. J. 2010, 16, 8300-8306 (frontispiece); DOI: 10.1002/chem. 201000623.

Th. Rehm, C. Schmuck; Ionpair Induced Self-Assembly in Aqueous Solvents. Chem. Soc. Rev. 2010, 39, 3597 - 3611; DOI: 10.1039/b926223g (invited review).

P. R. Wich, C. Schmuck; "Reversible and Non-Competitive Inhibition of -Tryptase by Protein Surface Binding of Tetravalent Peptide Ligands Identified from a Combinatorial Split-Mix-Library." Angew. Chem. Int. Ed. 2010,
49, 4113-4116
; DOI: 10.1002/anie.200907221.

Max Schütz, Bernd Küstner, Manuel Bauer, Carsten Schmuck, Sebastian Schlücker; "Synthesis of glass-coated SERS nanoparticle probes via SAMs with terminal SiO2 precursors." Small 2010, 6, 733-737; DOI: 10.1002/smll.200902065.

A. Breuning, B. Degel, F. Schulz, C. Büchold, M. Stempka, U. Machon, S. Heppner, C. Gelhaus, M. Leippe, M. Leyh, C. Kisker, J. Rath, A. Stich, J. Gut, P. J. Rosenthal, C. Schmuck, T. Schirmeister; "Michael-acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors with unusual amino acids." J. Med. Chem. 2010, 53, 1951-1963, DOI: 10.1021/jm900946n.

L. Hernandez-Folgado, D. Bareti , I. Piantanida, M. Marjanovi , M. Kralj, T. Rehm, C. Schmuck; "Guanidiniocarbonyl-pyrrole-aryl derivatives: structure tuning for spectrophotometric recognition of specific DNA and RNA sequences and antiproliferative activity." Chem. Eur. J. 2010, 16, 3036-3056; DOI:10.1002/chem.200901999.

C. Rether, W. Sicking, R. Boese, C. Schmuck; "Self-association of an indole based guanidinium-carboxylate-zwitterion: formation of stable dimers in solution and the solid state." Beilstein J. Org. Chem. 2010, 6, No. 3.

S. Niebling, S. K. Srivastava, C. Hermann, P. R. Wich, C. Schmuck, S. Schlücker; "Site-specific pKa
determination of the carboxylate-binding subunit in artificial peptide receptors." Chem. Commun. 2010, DOI: 10.1039/B926514G.







M. Merschky, C. Schmuck: "N-(Aminoiminomethyl)-carbamic acid, 1,1-dimethyethyl ester (Boc-Guanidine)." Electronic Encyclopedia of Reagents for Organic Synthesis (eEROS), 2009.

C. Jehn, B. Küstner, P. Adam, A. Marx, P. Ströbel, C. Schmuck, S. Schlücker: "Water Soluble SERS Lables Comprising a SAM with Dual Spacers for Controlled Bioconjugation." Phys. Chem. Chem. Phys., 2009, 11, 7499-7504.

N. Lindgren, L. Geiger, J. Razkin, C. Schmuck, L. Baltzer: "Downsizing Enzymatic Function by Chemical Methods - Arginine Mimics with Low pKa Values Increase Rates of RNA Model Compounds." Angew. Chem. 2009, 121, 6850-6853; Angew. Chem. Int. Ed. 2009, 48,6722-6725.

H. Kuchelmeister, C. Schmuck: " An Efficient Synthesis of an Orthogonally Protected Aromatic Diamine as Scaffold for Tweezer Receptors with Two Different Arms." Eur. J. Org. Chem. 2009, 4480-4485.

C. Schmuck, U. Michels, J. Dudaczek: "Hydrolytic activity of histidine-containing octapeptides in water identified by quantitative screening of a combinatorial library." Org. Biomol. Chem., 2009, 7, 4362-4368.

M. Merschky, C. Schmuck;* "Synthesis and kinetic studies of a low-molecular weight organocatalyst for phosphate hydrolysis in water." Org. Biomol. Chem. 2009, 7, 4895 - 4903.

U. Machon, C. Büchold, M. Stempka, T. Schirmeister, C. Gelhaus, M. Leippe, J. Gut, P. J. Rosenthal, C. Kisker, M. Leyh, C. Schmuck: "On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide sequences.
J. Med. Chem. 2009, 52, 5662-5672.

B. Küstner, M. Gellner, M. Schütz, F. Schöppler, A. Marx, P. Strobel, P. Adam, C. Schmuck, S. Schlücker: "SERS labels for red laser excitation: silica-encapsulated SAMs on tunable gold/silver nanoshells." Angew. Chem. Int. Ed. 2009, 48, 1950-1953.

M. Drayss, D. Blunk, J. Oomens, N. Polfer, C. Schmuck, B. Gao, T. Wyttenbach, M. Bowers, M. Schaefer: "Gas-phase structures of solution-phase zwitterions: Charge solvation or salt bridge?" Int. J. Mass Spec. 2009, 281, 97-100.

D. Haldar, C. Schmuck: "Metal-free double helices from abiotic backbones." Chem. Soc. Rev. 2009, 38, 363-71.

G. Gröger, V. Stepanenko, F. Würthner, C. Schmuck: "Step-wise self-assembly of a small molecule with two orthogonal binding interactions leads to single stranded linear polymers in DMSO." Chem. Commun. 2009, 698-700.






S. Srivastava, S. Niebling, B. Küstner, P. Wich, C. Schmuck, S. Schlücker: "Characterization of guanidiniocarbonyl pyrroles in water by pH-dependent UV Raman spectroscopy and component analysis." PCCP 2008, 10, 6770-6775.

D. Moiani, C. Cavallotti, A. Famulari, C. Schmuck: "Oxoanion binding by guanidiniocarbonyl pyrrole cations in water: A Combined DFT and MD Investigation." Chem. Eur. J. 2008, 14, 5207-5219.

L. Hernandez-Folgado, C. Schmuck, S. Tomic, I. Piantanida: "A novel pyrene-guanidiniocarbonyl-pyrrole cation efficiently differentiates between ds-DNA and ds-RNA by two independent, sensitive spectroscopic methods." Bioorg. Med. Chem. Lett. 2008, 18, 2977-2981.

Th. Rehm, V. Stepanenko, X. Zhang, F. Würthner, F. Gröhn, K. Klein, C. Schmuck: "A new type of soft vesicle forming molecule: an amino acid derived guanidiniocarbonyl pyrrole carboxylate zwitterion." Org. Lett. 2008, 10, 1469-1472.

Th. Rehm, C. Schmuck: "How to achieve self-assembly in polar solvents based on specific interactions? Some general guidelines." Chem. Commun. 2008, 801-813.

C. Schmuck, V. Bickert, M. Merschky, L. Geiger, D. Rupprecht, J. Dudaczek, P. Wich, Th. Rehm, U. Machon: "A facile and efficient multi-gram synthesis of N-protected guanidinocarbonyl pyrrole carboxylic acids." Eur. J. Org. Chem. 2008, 324-329.







C. Schmuck, J. Dudaczek: "Screening of a combinatorial library reveals peptide-based catalysts for phosphor-ester cleavage in water." Org. Lett. 2007, 9, 5389-5392.
C. Schmuck, D. Rupprecht: "The synthesis of highly functionalized pyrroles: A challenge in regioselectivity and chemical reactivity." Synthesis 2007, 3095-3110.

B. Küstner, C. Schmuck, P. Wich, C. Jehn, S. Schlücker: "UV resonance Raman spectroscopic monitoring of supramolecular complex formation: peptide recognition in aqueous solution." PCCP 2007, 9, 4598-4603.

C. Schmuck, V. Bickert: "Oxoanion Binding by Flexible Guanidiniocarbonyl Pyrrole-Ammonium Bis-Cations in Water: Increase of Complex Stability with Increasing flexibility of the Host." J. Org. Chem. 2007, 72, 6832-6839.

C. Schmuck, Th. Rehm, L. Geiger, M. Schäfer: "Synthesis and self-association properties of flexible guanidiniocarbonyl pyrrole-carboxylate-zwitterions in DMSO: Intra- versus intermolecular charge interactions." J. Org. Chem. 2007, 72, 6162-6170.

C. Schmuck, L. Hernandez-Folgado: "Synthesis of a new artificial host for the binding of dipeptides in water." Org. Biomol. Chem. 2007, 5, 2390-2394.

C. Schmuck: "Guest encapsulation within self-assembled molecular containers." Angew. Chem. Int. Ed. 2007, 46, 5830-5833.

C. Schmuck, J. Dudaczek: "Ion pairing between the chain ends induces folding of a flexible zwitterion in methanol." Eur. J. Org. Chem. 2007, 3326-3330.

C. Schmuck, D. Rupprecht, M. Junkers, T. Schrader: "Artificial Ditopic RGD Receptors." Chem. Eur. J. 2007, 13, 6864-6873.

S. Schlund, C. Schmuck, B. Engels: "How Important Is Molecular Rigidity for the Complex Stability of Artificial Host–Guest Systems? A Theoretical Study on Self-Assembly of Gas-Phase Arginine." Chem. Eur. J. 2007, 13, 6644-6653.

C. Schmuck, P. Wich, B. Küstner, W. Kiefer, S. Schlücker: "Direct and label-free detection of solid-phase bound compounds using surface enhanced Raman scattering (SERS) microspectroscopy." Angew. Chem. Int. Ed. 2007, 46, 4786-4789.

C. Schmuck, P. Wich: "The development of artificial receptors for small peptides using combinatorial approaches." Topics Curr. Chem. 2007, 277, 3-30. (Creative Chemical Sensor Systems, Volume Editor, Th. Schrader)

C. Schmuck, Th. Rehm: "Foldamer Hybrids: Defined Supramolecular Structures from Flexible Molecules." in Foldamers (Eds. Stefan Hecht, Ivan Huc), Wiley-VCH, 2007.

C. Schmuck, M. Heller: "Solid phase synthesis of a new biomimetic receptor for anionic carbohydrates." Org. Biomol. Chem. 2007, 5, 787-791.

C. Schmuck, Th. Rehm, K. Klein, F. Gröhn: "Formation of Vesicular Structures via the Self-Assembly of a Flexible Bis-Zwitterion in DMSO." Angew. Chem. Int. Ed. 2007, 46, 1693-1697.






C. Schmuck, D. Rupprecht, W. Wienand: "Sequence-Dependent Binding of Dipeptides in Water by an Artificial Receptor." Chem. Eur. J. 2006, 12, 9186-9195.

C. Schmuck: "How to Improve Guanidinium Cations for Oxoanion Binding in Aqueous Solution? The Design of Artificial Peptide Receptors." Coord. Chem. Rev. 2006, 250, 3053-3067.

C. Schmuck, P. Wich: "Combinatorial receptor finding – large and random vs. small and focused libraries." New J. Chem. 2006, 30, 1377-1385.

C. Schmuck, U. Machon: "2-Guanidiniocarbonyl-Furans as a new Class of Potential Anion Hosts: Synthesis and first Binding Studies." Eur. J. Org. Chem. 2006, 4385-4392.
G. Bringmann, H. Scharl, K. Maksimenka, K. Radacki, H. Braunschweig, P. Wich, C. Schmuck: "Atropo-Diastereoselective Cleavage of Configurationally Unstable Biaryl Lactones with Amino Acid Esters." Eur. J. Org. Chem. 2006, 4349-4361.

C. Schmuck, P. Wich: "Sequence dependent stereoselectivity in the binding of tetrapeptides in water by flexible artificial receptors." Angew. Chem. Int. Ed. 2006, 45, 4277-4281.

C. Schmuck, Th. Rehm, F. Gröhn, K. Klein, F. Reinhold: "Self-Assembly of a Flexible Bis-Zwitterion in Polar Solution: Formation of Discrete Nanometer-Sized Cyclic Dimers." J. Am. Chem. Soc. 2006, 128, 1430-1431.

C. Schmuck, M. Schwegmann: "A naked-eye sensor for the selective detection of citrate – but not tartrate or malate - in aqueous solvents." Org. Biomol. Chem. 2006, 4, 836-838.

C. Schmuck, M. Heil: "One-Armed Artificial Receptors for the Binding of Polar Tetrapeptides in Water: Probing the Substrate Selectivity of a Combinatorial Receptor Library." Chem. Eur. J. 2006, 12, 1339-1348.

C. Schmuck, D. Rupprecht, C. Urban, N. Walden: "Syntheses of Orthogonally Protected Pyrrole Tricarboxylic Acid Derivatives: Versatile Building Blocks for Pyrrole Containing Compounds." Synthesis 2006, 89-96.






U. Kaeppler, N. Stiefl, M. Schiller, R. Vicik, A. Breuning, W. Schmitz, D. Rupprecht, C. Schmuck, K. Baumann, J. Ziebuhr, T. Schirmeister: "A new lead for non-peptidic active-site directed inhibitors of the SARS coronavirus main protease discovered by a combination of screening and docking methods." J. Med. Chem. 2005, 48, 6832-6842.

C. Schmuck, M. Heil, J. Scheiber, K. Baumann: "Charge Interactions do the Job: A Combined Statistical and Combinatorial Approach to Find Artificial Receptors for Tetrapeptide Binding in Water." Angew. Chem. Int. Ed. 2005, 44,7208-7212.

C. Schmuck, J. Dudaczek: "New guanidinium based carboxylate receptors derived from 5-amino-pyrrole-2-carboxylate: synthesis and first binding studies." Tetrahedron Lett. 2005, 46, 7101-7105.

C. Schmuck, M. Schwegmann: "Recognition of anionic carbohydrates by an artificial receptor in water." Org. Lett. 2005, 7, 3517-3520.

S. Schlund, C. Schmuck, B. Engels: "Knock-Out - Analogues as a Tool to quantify Supramolecular Processes: a Theoretical Study of Molecular Interactions in Guanidiniocarbonyl Pyrrole Carboxylate Dimers.” J. Am. Chem. Soc. 2005, 127, 11115-11124.

C. Schmuck, L. Geiger: "Efficient complexation of N-acetyl-amino acid carboxylates in water by an artificial receptor: unexpected cooperativity in the binding of glutamate but not aspartate." J. Am. Chem. Soc. 2005, 127, 10486-10487.

C. Schmuck, P. Frey, M. Heil: "Inhibition of Fibril Formation of Ab by Guanidiniocarbonyl Pyrrole Receptors." ChemBioChem 2005, 6, 628-631.

C. Schmuck, M. Schwegmann: "A molecular flytrap for the selective binding of citrate and other tris-carboxylates in water." J. Am. Chem. Soc. 2005, 127, 3373-3379.

C. Schmuck, U. Machon: "Amino Acid binding by 2-(Guanidinio- carbonyl) Pyridines in Aqueous Solvents: A Comparative Binding Study Correlating Complex Stability with Stereoelectronic Factors." Chem. Eur. J. 2005, 11, 1109-1118.

C. Schmuck, S. Graupner: "Amino acid binding in water by a new guanidinio­carbonyl pyrrole dication: The effect of the experimental conditions on complex stability and stoichiometry." Tetrahedron Lett. 2005, 46, 1295-1298.

C. Schmuck, L. Geiger: "Design and synthesis of a new class of arginine analogues with an improved anion binding site in the side chain." Chem. Commun. 2005, 772-774.






M. Schäfer, C. Schmuck, L. Geiger, M. J. Chalmers, C. L. Hendrickson, A. G. Marshall: "Structurally related non-covalent complexes examined by quadrupole ion trap (QIT) MS2 and infrared multiphoton dissociation Fourier transform ion cyclotron resonance mass spectrometry IRMPD-FT-ICR MS: evidence for salt-bridge structures in the gas phase." Int. J. Mass Spec. 2004, 237, 33-45.

C. Schmuck, L. Geiger: "Dipeptide Binding in Water by a De-novo Designed Guanidiniocarbonylpyrrole Receptor." J. Am. Chem. Soc. 2004, 126, 8898-8899.

C. Schmuck, L. Geiger: "Dimerization of a guanidiniocarbonyl pyrrole cation in DMSO that can be controlled by the counter anion." Chem. Commun. 2004, 1698 - 1699.

C. Schmuck, W. Wienand, L. Geiger: "Bioorganic Receptors for Amino Acids and Peptides. Combining rational design with combinatorial chemistry." in Highlights in Bioorganic Chemistry: Methods and Applications (Eds. C. Schmuck, H. Wennemers), Wiley-VCH, 2004.







C. Schmuck, V. Bickert: "N’-alkylated guanidiniocarbonyl pyrroles: New receptors for amino acid recognition in water." Org. Lett. 2003, 5, 4579 - 4581.

M. Schäfer, C. Schmuck, M. Heil, H. J. Cooper, C. L. Hendrickson, M. J. Chalmers, A. G. Marshall: "Determination of the Gas-phase Activation Energy for the Unimolecular Dissociation of a Non-covalent Complex by Infrared Multiphoton Dissociation Tandem Fourier Transform Ion Cyclotron Resonance Mass Spectrometry." JASMS 2003, 14,1282-1289.

C. Schmuck, M. Heil: "Peptide binding by one-armed receptors in water: screening of a combinatorial library for binding of Val-Val-Ile-Ala." ChemBioChem. 2003, 4, 1232-1238.

C. Schmuck, L. Geiger: "Carboxylate Binding by Guanidiniocarbonyl Pyrroles: From Self-Assembly to Peptide Receptors." Curr. Org. Chem. 2003, 7, 1485-1502.

C. Schmuck: "Molecules with helical structures: How to build a molecular spiral staircase?" Angew. Chem. Int. Ed. 2003, 42,2448-2452.

C. Schmuck, M. Heil: "Targeting the C-Terminus of b-Amyloid with a Tripeptide-based Cationic Receptor: A Combinatorial Approach to a Quantitative Understanding of Peptide Binding." Org. Biomol. Chem. 2003, 1, 633-636.

C. Schmuck, W. Wienand: "Highly Stable Self-Assembly in Water: Ion Pair Driven Dimerization of a Guanidiniocarbonyl Pyrrole Carboxylate Zwitterion." J. Am. Chem. Soc. 2003, 125, 452-459.






C. Schmuck, W. Wienand: "The First Efficient Synthesis and Optical Resolution of Monosubstituted Cyclotribenzylenes." Synthesis 2002, 655-663.







C. Schmuck, M. Heil, M. Dechantsreiter, U. E. Hackler: "Stereoselective Complexation of Amino Acid Carboxylates in Aqueous Solutions: Automated Parallel Synthesis of a Guanidiniocarbonyl-Pyrrole Receptor Library." JALA 2001, 6, 51-53.

C. Schmuck: "Peptiden auf den Leib geschneidert – Von der molekularen Erkennung zum Design neuer Wirkstoffe." ChiuZ 2001, 35, 356-366.

C. Schmuck, W. Wienand: "Self-Complemtary Quadruple Hdrogen-Bonding Motifs as a Functional Principle: From Dimeric Supramolecules to Supramolecular Polymers." Angew. Chem. Int. Ed. 2001, 40, 4363-4369.

C. Schmuck, M. Heil, U. E. Hackler, M. Dechantsreiter: "Stereoselective Complexation of Amino Acid Carboxylates in Aqueous Solutions: Automated, Parallel Synthesis of a Guanidiniocarbonyl-Pyrrole Receptor Library." Proceedings of ECSOC-5, September 1-30, 2001.

C. Schmuck, M. Heil: "Anion Dependent Dimerization of a Guanidiniocarbonyl Pyrrole Cation in DMSO." Org. Lett. 2001, 3, 1253-1256.

C. Schmuck: "Self-Assembly of 2-(guanidiniocarbonyl)-pyrrole-4-carboxylate in dimethyl sulfoxide: an entropy driven oligomerization." Tetrahedron 2001, 57, 3063-3067.

F. Vögtle, C. Reuter, W. Wienand, C. Schmuck: "A Self-threaded Molecular 8." Chem. Eur. J. 2001, 7, 1728-1733.

C. Schmuck, J. Lex: "C-H-O Interactions as Isofunctional Replacements for N-H-O Interactions - Dimer Formation of Methyl 5-Amido-Pyrrole-2-Carboxylates in the Solid State." Eur. J. Org. Chem. 2001, 1519-1523.






C. Schmuck: "Self-Folding Molecules: A Well Defined, Stable Loop Formed by a Carboxylate-Guanidinium Zwitterion in DMSO." J. Org. Chem. 2000, 65, 2432-2437.

C. Schmuck: "Carboxylate Binding by 2-(Guanidiniocarbonyl) Pyrrole Receptors in Aqueous Solvents: Improving the Binding Properties of Guanidinium Cations Through Additional Hydrogen Bonds." Chem. Eur. J. 2000, 6, 709-718.






C. Schmuck, J. Lex: "Acetate Binding Within a Supramolecular Hydrogen Bonding Network Formed by a Guanidiniocarbonyl Pyrrole Cation in the Solid State." Org. Lett. 1999, 1, 1779-1781.

C. Schmuck: "Highly Stable Self-Association of 5-(Guanidiniocarbonyl)-1H-Pyrrole-2-Carboxylate in DMSO - The Importance of Electrostatic Interactions." Eur. J. Org. Chem. 1999, 2397-2403.

C. Schmuck: "Side Chain Selective Binding of N-Acetyl-a-Amino Acid Carboxylates by a 2-(Guanidinocarbonyl)pyrrole Receptor in Aqueous Solvents." Chem. Commun. 1999, 843-844.




before 1999


R. Breslow, C. Schmuck: "The Mechanism of Thiazolium Catalysis." Tetrahedron Lett. 1996, 37, 8241-8242.

R. Breslow, C. Schmuck: "Goodness of Fit in Complexes between Substrates and Ribonuclease Mimics; Effects on Binding, Catalytic Rate Constants and Regiochemistry." J. Am. Chem. Soc. 1996, 118, 6601-6605.

W. R. Roth, V. Staemler, M. Neumann, C. Schmuck: "Radikalstabilisierungs­energie; das MMEVBH-Kraftfeld." Liebigs Ann. 1995, 1061-1118.






Beyer/Walter Organische Chemie

Tanja Schirmeister, Carsten Schmuck, Peter R. Wich, HIrzel Verlag, 2015, ISBN: 978-3-77761-673-5


Basisbuch Organische Chemie

Carsten Schmuck, Pearson-Studium, 2. aktualisierte und erweiterte Auflage, 2018, ISBN 978-3-86894-333-7


Chemie für Mediziner

Carsten Schmuck, Bernd Engels, Tanja Schirmeister, Reinhold Fink, Pearson-Studium, 2. Auflage 2016; ISBN 978-3868942989


Highlights in Bioorganic Chemistry: Methods and Application

Herausgeber: Carsten Schmuck, Helma Wennemers, Wiley-VCH, 2004




Proceedings and Abstracts of Papers


P. R. Wich, C. Schmuck; Surface Recognition and Inhibition of β-Tryptase by Tetravalent Peptide Ligands. Peptide Science 2010: Proceedings of the Fifth International Peptide Symposium, Kyoto, Japan, 04.-09. Dec 2010, (Ed.: N. Fujii, Y. Kiso), The Japanese Peptide Society, 2011, p 59.

M. Gellner, M. Schütz, M. Salehi, J. Packeisen, P. Ströbel, A. Marx, C. Schmuck, S. Schlücker; SERS microscopy: plasmonic nanoparticle probes and biomedical applications. Proc. of SPIE Vol. 7757, 77570M, 2010; doi: 10.1117/12.859253.

P. Wich, C. Schmuck; Stereoselective binding of peptides by artificial receptors in water: New insights into the molecular recognition of biologically relevant substrates. Abstracts of Papers, 234th ACS National Meeting, Boston, MA, United States, August 19-23, 2007.

C. Schmuck; Anion recognition in aqueous solvents using modified guanidinium cations. Abstracts of Papers, 234th ACS National Meeting, Boston, MA, United States, August 19-23, 2007.

C. Schmuck; Guanidiniocarbonyl pyrroles: a versatile carboxylate binding site. J. Porphyrins Phthalocyanines 2006, 10, 392.

M. Schäfer, C. Schmuck, L. Geiger, M. J. Chalmers, C. L. Hendrickson, A. G. Marshall; Structurally related non-covalent complexes examined by quadrupole ion trap (QIT) MS2 and infrared multiphoton dissociation Fourier transform ion cyclotron resonance mass spectrometry IRMPD-FT-ICR MS: evidence for salt-bridge structures in the gas phase, Proceedings of the 52nd ASMS Conference on Mass Spectrometry and Allied Topics; Nashville, TN, USA, 2004.

C. Schmuck; Bioorganic receptors for amino acids and peptides: Combining rational design with combinatorial chemistry. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, PA, United States, August 22-26, 2004.

C. Schmuck; Highly stable self-association of guanidiniocarbonyl pyrrole carboxylate zwitterions in aqueous solvents: From dimers to supramolecular oligomers” Abstracts of Papers, 228th ACS National Meeting, Philadelphia, PA, United States, August 22-26, 2004.

M. Schäfer, C. Schmuck, M. Heil, H. J. Cooper, C. L. Hendrickson, M. J. Chalmers, A. G. Marshall; Determination of the Activation Energy for Unimolecular Dissociation of a Non-Covalent Gas-Phase Peptide: Substrate Complex by Infrared Multiphoton Dissociation Fourier Transform Ion Cyclotron Resonance Mass Spectrometry, Proceedings of the 51st ASMS Conference on Mass Spectrometry and Allied Topics; Montreal, Canada, 2003

L. J. Kemp, C. Schmuck; Molecular recognition, stereoselective complexation of small peptides and amino acid carboxylates in aqueous solutions: Automated, parallel synthesis of a guanidinocarbonyl pyrrole receptor library. Abstracts of Papers, 224th ACS National Meeting, Boston, MA, United States, August 18-22, 2002.

C. Schmuck, M. Heil, U. E. Hackler, M. Dechantsreiter; Stereoselective Complexation of Amino Acid Carboxylates in Aqueous Solutions: Automated, Parallel Synthesis of a Guanidiniocarbonyl-Pyrrole Receptor Library. Proceedings of ECSOC-5, 2001 (Editors: O. Kappe, P. Merino, A. Marzinzik, H. Wennemers, T. Wirth, J.-J. Vanden Eynde, S.-K. Lin)




Other Publications


Die Kraft des Nichtkovalenten

Nachrichten aus der Chemie Oktober 2012, 979-985.


Neue Wege zu Nanoteilchen

Beitrag zu den Berichten aus Forschung und Lehre der Universität Duisburg-Essen, Unikate 37/2010.


Molekulare Fußbälle aus Kohlenstoff

Buchbeitrag gemeinsam mit Prof. W. Malisch (Institut für Anorganische Chemie der Universität Würzburg) in „Fußball - eine Wissenschaft für sich“ (Hrsg. H. G. Weigand), Verlag Königshausen & Neumann, 2006.


Supramolecular Chemistry at its best

Bericht über die ESF Konferenz; Supramolecular Chemistry: Molecular Architectures and Systems“, vom 14. – 19. Oktober in Obernai, Frankreich 2005;
Nachrichten aus Chemie, Technik und Labor 2006, 60.


Modern Physical Organic Chemistry

Buchrezension zu „Modern Physical Organic Chemistry “ von E. V. Anslyn, D. A. Dougherty, University Science Books, Sausalito, California, 2006; in Angew. Chem. 2006, 118, 1036-1037.


Chemische Handschuhe helfen bei der Suche nach neuen Antibiotika

Bericht über den SFB 630 in der Zeitschrift „Blick“, dem Magazin der Universität Würzburg für Forschung und Lehre; Ausgabe 1/2005, zusammen mit PD Dr. Knut Ohlsen.


Internationale Chemieolympiade 2005

Bericht über die 37. Internationale Chemieolympiade in Taipei/Taiwan 2005;
Nachrichten aus Chemie, Technik und Labor 2005, 955.


GAFOC III: Horizonte der Chemie

Tagungsbericht über das dritte Deutsch-Amerikanische Symposium „Horizonte der Chemie“ vom 15. – 18. Juli im Kloster Seeon; Nachrichten aus Chemie, Technik und Labor 2004, 1046-1049.


Chemie in unserer Zeit-Rätsel

Autor der folgenden chemischen Rätsel in der Zeitschrift Chemie in unserer Zeit: 2/2000, 5/2000, 2/2001, 4/2001, 1/2002, 5/2002, 1/2003, 5/2003 und 1/2004


Philosophie für’s Labor?

Buchrezension zu „Chemical Discovery and the Logcians’ Program “ von J. Berson, Wiley-VCH, Weinheim, 2003; Nachrichten aus Chemie, Technik und Labor 2003, 1170.


Von brennenden Gardinen und dem Funken der Begeisterung

Artikel in der Zeitschrift Faszination Chemie (Heft 03/2003)


Chemische Inspiration

Buchrezension zu „Stimulating Concepts in Chemistry“, Hrsg. von F. Vögtle, J. F. Stoddart, M. Shibasaki, Wiley-VCH, Weinheim, 2000; Nachrichten aus Chemie, Technik und Labor 2001, 942-943.


Die Mischung macht’s

Tagungsbericht zu den Steinheimer Gesprächen für den Hochschullehrernachwuchs 1999; Nachrichten aus Chemie, Technik und Labor 1999, 1110.


Die Internationale Chemieolympiade 1995

Erfahrungsbericht über die XXII. Internationale Chemieolympiade in Peking/China 1995; Chemie in unserer Zeit 1995, 285.






1.)       Prof. Dr. Wolfgang Kiefer, Dipl.-Chem. Bernd Küstner, Prof. Dr. Alexander Marx, Dr. Sebastian Schlücker, Prof. Dr. Carsten Schmuck, Dr. Philipp Ströbel; Tissue Diagnostics based on surface-enhanced Immuno-Raman Microspectroscopy and Imaging. DE 10 2006 000 775 A1 2007.07.12

Kiefer, Wolfgang; Kuestner, Bernd; Marx, Alexander; Schlucker, Sebastian; Schmuck, Carsten; Stroebel, Philipp.  Imaging diagnostic method using surface-enhanced oscillation spectroscopy. Ger. Offen. (2007), 14 pp. CODEN: GWXXBX  DE  102006000775 A1 20070712  CAN 147:137073 AN 2007:754970


2.)       PD Dr. Sebastian Schlücker, Prof. Dr. Carsten Schmuck, Dipl.-Chem. Bernd Küstner; Compounds and markers for surface-enhanced Raman scattering. Europäisches Patent, EP 07 01 8757.0, angemeldet am 24.09.2007.

Kuestner, Bernd; Schluecker, Sebastian; Schmuck, Carsten. Compounds and markers for surface-enhanced Raman scattering. PCT Int. Appl. 2009, 123pp. CODEN: PIXXD2 WO 2009040114 A2 20090402 CAN 150:347854  AN 2009:385052

Schluecker, Sebastian; Kuestner, Bernd; Schmuck, Carsten. Compounds and markers for surface-enhanced Raman scattering. Eur. Pat. Appl.  (2009), 53pp. CODEN: EPXXDW EP 2040075 A1 20090325 CAN 150:347848 AN 2009:352752


3.)       Prof. Dr. Tanja Schirmeister, Prof. Dr. Carsten Schmuck, Dr. Uwe Machon, Dipl.-Chem. Sebastian Langolf, Prof. Dr. Knut Baumann, Sebastian G. Rohrer; N-geschützte Guanidin-substituierte Furane, Thiophene und Pyrrole als Cystein-Protease-Inhibitoren. DE 10 2008 049767.3, angemeldet am 30.09.2008.