Prof. Dr. Dr. h.c. mult. Robert Huber FRS

Center of Medical Biotechnology
Room: S03 S02 A45
University of Duisburg-Essen
45141 Essen
Max Planck Institute of Biochemistry
Am Klopferspitz 18
82152 Martinsried

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• +49 201 183 4141
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• ZMB Research Program
  Molecular and Chemical Cell Biology

Research Overview

Professional interests

Structure and function of biological macromolecules, in particular those of large complex aggregates.

Systems studied

• Proteases and their natural and synthetic inhibitors.
• Metalloenzymes (iron, nickel, molybdenum, copper).
• Proteins of the immune system (antibodies and antibody receptors).
• Protein hormones and their receptors.
• Protein kinases.
• Proteins of amino acid biosynthesis (PLP containing enzymes).
• Proteins of cofactor and vitamin biosynthesis.
• Proteins of energy and electron transport.

Methods development

• Patterson methods in crystallography.
• Methods of structure determination of proteins and protein ligand complexes by NMR.
• Synthesis and use of electron rich metal clusters.
• Crystal annealing and improvement, methods and instruments.
• Analysis and evaluation of targets for research and application in pharmacology and crop science.

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