Welcome to the Research Group of Prof. Dr. Carsten Schmuck
We are fascinated by supramolecular chemistry. We strive to understand how molecules interact with each other, how non-covalent interactions control the stability and selectivity of molecular interactions and how we can use this understanding to develop supamolecular systems that either bind to biological targets such as proteins or nucleic acids or self-assemble with themselves to form supramolecular polymers and gels.
Explore our websites to learn more about who we are and what we do. Of course as a university group we are also devoted to teaching and you will find some useful information here regarding the classes and lectures we teach.
News from our Research
Haos work on morphology dependent cell imaging by a self-assembling amphiphilic peptide just got accepted by Angewandte Chemie. Congratulations. Hao could show that the peptide amphiphile self-assembles concentration dependently into different types of nanostructures, tadpole and bolashped aggregates at low concentration and fibers at higher. These aggregates polymerize in the presence of a cell membrane (but not in free solution) into a red fluorescence polydiacetylene. As the tadpole and bolashaped aggregates are taken up by cells, but the fibers are not, morphology dependent cell imaging is observed. The fibers just stain the membrane whereas the tadpole and bolashaped aggregates stain the endosomes within the cells. Watch out for the final paper in print.
We are always looking for talented and enthusiastic coworkers who want to be part of our research group on all levels (bachelor or master student, PhD student or postdoc).
Interested in developing and synthesizing new supramolecular ligands and testing how they bind to a protein or can be used as an artifical gene transfection vector? Or do you prefer to study self-assembling molecules and explore how you can use such compounds for switchable polymers and gels? If you want to become part of our group contact us (email).