The CRC1430 is excited to annouce the association of Dr. Dana Branzei, a renowned expert in the field of DNA damage repair ...

The CRC1430 is excited to annouce the association of Dr. Dana Branzei, a renowned expert in the field of DNA damage repair and chromosome structure. Dana's work focuses on uncovering the functions of the Chl1 helicase and its roles in both endogenous replication and upon acute DNA damage, with emphasis on DNA damage tolerance and sister chromatid cohesion. The goal is to elucidate how replisome-associated factors, such as Chl1, regulate cell cycle transitions. To achieve this goal her group employs a combination of yeast genetics and molecular biology techniques.

The CRC1430 welcomes Prof. Dr. Barbara T. Grünwald as a principal investigator, bringing her expertise in Tumor Heterogeneity ...

The CRC1430 welcomes Prof. Dr. Barbara T. Grünwald as a principal investigator, bringing her expertise in Tumor Heterogeneity and Translational Systems Biology to the team. Her work focuses on transcriptional regulators of differentiation state transitions in pancreatic tumor fibroblasts. Barabara's group has identified distinct transcriptional drivers of regional cancer-associated fibroblast states and they are now aiming to deeply define the corresponding cell state transitions, their specific triggers and, most importantly, their precise transcriptional regulatory mechanisms.

We are delighted to announce that Dr. Kathrin Thedieck has joined the CRC1430 as an associated principal investigator. The ...

We are delighted to announce that Dr. Kathrin Thedieck has joined the CRC1430 as an associated principal investigator. The work in her lab for Metabolic Signaling (www.metabolic-signaling.eu) focuses on the control of metabolic homeostasis through kinase signaling networks converging on the metabolic master regulator mTOR (mammalian / mechanistic target of rapamycin) in health and disease. Kathrin's lab adopts biochemistry, cell biology, proteomics, metabolomics and systems modelling approaches.

The CRC1430 is pleased to welcome Dr. Katarzyna Kliza as an associated principal investigator. Katarzyna is a Research Group ...

The CRC1430 is pleased to welcome Dr. Katarzyna Kliza as an associated principal investigator. Katarzyna is a Research Group Leader at the MPI of Molecular Physiology, where she is engaged in studying the Decoding of Post-Translational Modification Signalling Networks, with a specific focus on ADP-ribosylation. Her research involves a multifaceted and interdisciplinary approach, incorporating proteomics, biochemistry, molecular, and cell biology techniques.