Join - Open Positions

A01 • Position I: PhD Position (TV-L E13, 65%)

Melanoma persister states • lipidomics • MAPKi resistance • cell state tracing

• University Hospital Essen • PI: Prof. Alexander Roesch • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-a01.php

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A01 • Position II: Bioinformatician / Data Analyst Position (TV-L E13, 50%)

Bioinformatics workflows • RNA-seq and single-cell analysis • spatial transcriptomics • high-dimensional imaging data • multi-omics integration

• University Hospital Essen • PI: Prof. Alexander Roesch • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-a01.php

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A02 • Position I: PhD Position (TV-L E13, 65%)

Lipid metabolic reprogramming • RAS signaling • patient-derived tumor fragments • therapy-induced adaptation • lipid-targeted interventions

• University Hospital Essen / BIT • PI: Prof. Jens Siveke • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-a02.php

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A02 • Position II: PhD Position (TV-L E13, 65%)

Melanoma cell state plasticity • lipid metabolic reprogramming • immunotherapy resistance • syngeneic mouse models • tumor–immune interactions

• University Hospital Bonn / IEO • PI: Dr. Nicole Glodde • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-a02.php

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A03 • PhD Position (TV-L E13, 65%)

Theranostics • PET-imaging • melanoma metabolic rewiring • melanoma biomarker

• University Hospital Essen, Nuclear Medicine, Preclinical Theranostics • PI: Prof. Katharina Lückerath • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-a03.php

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A04 • PhD Position (TV-L E13, 65%)

Angiogenesis • MAPKi resistance • metabolomics

• University Hospital Essen • PI: Prof. Lisa Becker • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-a04.php

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B01 • PhD Position (TV-L E13, 65%)

Melanoma Tumor Microenvironment • spatial multi-omics • Immunotherapy • Fibroblast polarization

• University Hospital Essen • PI: Dr. Phyllis Fung-Yi Cheung • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-b01.php

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B02 • PhD Position (TV-L E13, 65%)

Immune Evasion • Tumor Microenvironment • multiOMICs • IO Resistance 

• University Hospital Essen • PI: Prof. Barbara Grünwald • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-b02.php

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B03 • Position I: PhD Position I (TV-L E13, 65%)

CAR-T cell engineering • glucocorticoid shielding • melanoma immune escape • spatial immune profiling

• University Hospital Bonn • PI: Prof. Michael Hölzel • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-b03.php

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B03 • Position II: PhD Position II (TV-L E13, 65%)

CRISPR/Cas9 screening • functional genomics • CAR-T cell optimization • immune checkpoint editing

• University Hospital Essen • PI: Prof. Christian Reinhardt• Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-b03.php

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B04 • PhD Position (TV-L E13, 65%)

Melanoma persister states • metastasis • ICI resistance • cell state tracing in vivo models •DNA barcoding technologies and multiomics

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B05 • Position I: PhD Position (TV-L E13, 65%)

Tumor-associated Macrophages • Spatial Proteomics • LMD-coupled LC-MS/MS • Multi-Omics Integration

• University Hospital Essen • PI: Prof. Daniel Engel • Available from 1 October 2026 • 3 years
• About the project: https://www.uni-due.de/crc1752/project-b05.php

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B05 • Position II: PhD Position (TV-L E13, 65%)

Tumor-associated Macrophages • metabolic polarization • immunotherapy resistance • patient-derived models

• University Hospital Essen • PI: Prof. Alexander Roesch • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-b05.php

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B06 • Position I: PhD Position (TV-L E13, 65%)

Neutrophil–T cell interactions • live-cell imaging • cytokine signaling • functional immunology • few-cell proteomics

• ISAS, Dortmund • PI: Prof. Matthias Gunzer • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-b06.php

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B06 • Position II: PhD Position (TV-L E13, 65%)

Tumor-associated neutrophils • tumor–immune interactions • 2D/3D co-culture models • cytokine profiling • multiplex imaging

• University Hospital Essen • PI: Dr. Renáta Váraljai • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-b06.php

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C01 • PhD Position (TV-L E13, 100%)

Computational biology • single-cell & spatial transcriptomics • cell–cell communication inference • tumor microenvironment mapping • perturbation modeling

• University Hospital Essen / IKIM • PI: Prof. Florian Rambow • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-c01.php

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C02 • PhD Position (TV-L E13, 100%)

Bioinformatics • Algorithm engineering • Bayesian statistics • Machine learning

• University Hospital Essen • PI: Prof. Johannes Köster • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-c02.php

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CRC 1752 • Cross-Project Bioinformatics Postdoc Position (TV-L E13, 100%)

Multi-omics data integration • single-cell and spatial transcriptomics • automated hypothesis testing • reproducible workflows • cross-project data analysis support

• University Hospital Essen / IKIM • PIs: Prof. Johannes Köster & Prof. Florian Rambow • Available from 1 October 2026 • 3 years + 9 months

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Z01 • Position I: Scientific Coordinator (TV-L E13, 100%)

Research management • consortium coordination • multi-omics workflows • science communication

• University Hospital Essen • PI: Prof. Alexander Roesch / Prof. Kathrin Thedieck • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-z01.php

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Z01 • Position II: Administrative Management Assistant (TV-L E9, 50%)

Project administration • financial management • personnel administration • event organization

• University Hospital Essen • PI: Prof. Alexander Roesch / Prof. Kathrin Thedieck • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-z01.php

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Z02 • PhD Position (TV-L E13, 100%)

Research data management • FHIR-based medical data standards • clinical-molecular data integration • DevOps workflows • ETL/CDC pipelines • data stewardship

• University Hospital Essen / IKIM • PI: Prof. Felix Nensa • Available from 1 October 2026 • 3 years + 9 months
• About the project: https://www.uni-due.de/crc1752/project-z02.php

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