ZMB Member Christoph Kleinschnitz
ZMB Member
Christoph Kleinschnitz
Next ZMB-Member
Prof. Dr. Christoph Kleinschnitz
Director of:
Clinic for Neurology
University Hospital Essen
Hufelandstr. 55
45147 Essen
- +49 201 723 246 0
- Website
- Press Releases
- Selected Publications
- Publication Metrics
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- ZMB Research Program
Molecular and Chemical Cell Biology
Research Overview
- Peripheral Nervous System Disorders
- Clinical and experimental neuroimmunology
- Clinical stroke research
- Headache and dizziness
- Multiple sclerosis/neuroimmunology
- Thrombo-inflammation
- Clinical neuro-oncology
Selected Publications
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Different Treatment Outcomes of Multiple Sclerosis Patients Receiving Ocrelizumab or OfatumumabIn: Annals of Neurology , Vol. 97 2025, Nr. 3, pp. 583 – 595DOI (Open Access)
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Alteration of LARGE1 abundance in patients and a mouse model of 5q-associated spinal muscular atrophyIn: Acta Neuropathologica , Vol. 147 2024, Nr. 1, 53DOI (Open Access)
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Cell-mediated cytotoxicity within CSF and brain parenchyma in spinal muscular atrophy unaltered by nusinersen treatmentIn: Nature Communications , Vol. 15 2024, Nr. 1, 4120DOI (Open Access)
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Spinal astrocyte dysfunction drives motor neuron loss in late-onset spinal muscular atrophyIn: Acta Neuropathologica , Vol. 145 2023, Nr. 5, pp. 611 – 635DOI (Open Access)
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Telemedicine in Neuro-Oncology : An Evaluation of Remote Consultations during the COVID-19 PandemicIn: Cancers , Vol. 15 2023, Nr. 16, 4054DOI (Open Access)
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ACKR3 regulates platelet activation and ischemia-reperfusion tissue injuryIn: Nature Communications , Vol. 13 2022, Nr. 1, 1823DOI (Open Access)
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Safety and efficacy of prednisone versus placebo in short-term prevention of episodic cluster headache : A multicentre, double-blind, randomised controlled trialIn: The Lancet Neurology , Vol. 20 2021, Nr. 1, pp. 29 – 37
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A preliminary study on machine learning-based evaluation of static and dynamic fet-pet for the detection of pseudoprogression in patients with idh-wildtype glioblastomaIn: Cancers , Vol. 12 2020, Nr. 11, pp. 3080DOI, Online Full Text (Open Access)
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Nusinersen in adults with 5q spinal muscular atrophy : A non-interventional, multicentre, observational cohort studyIn: The Lancet Neurology , Vol. 19 2020, Nr. 4, pp. 317 – 325
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Differential impact of pure glyphosate and glyphosate-based herbicide in a model of peripheral nervous system myelinationIn: Acta Neuropathologica , Vol. 136 2018, Nr. 6, pp. 979 – 982
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Functional relevance of the anaphylatoxin receptor C3aR for platelet function and arterial thrombus formation marks an intersection point between innate immunity and thrombosisIn: Circulation , Vol. 138 2018, Nr. 16, pp. 1720 – 1735DOI (Open Access)
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CK2b regulates thrombopoiesis and Ca21-Triggered platelet activation in arterial thrombosisIn: Blood , Vol. 130 2017, Nr. 25, pp. 2774 – 2785
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Dimethyl fumarate accelerates peripheral nerve regeneration via activation of the anti-inflammatory and cytoprotective Nrf2/HO-1 signaling pathwayIn: Acta Neuropathologica , Vol. 133 2017, Nr. 3, pp. 489 – 491
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Stimulation of the mesencephalic locomotor region for gait recovery after strokeIn: Annals of Neurology , Vol. 82 2017, Nr. 5, pp. 828 – 840
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Stroke-induced chronic systolic dysfunction driven by sympathetic overactivityIn: Annals of Neurology , Vol. 82 2017, Nr. 5, pp. 729 – 743DOI (Open Access)
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ADAMTS13-mediated thrombolysis of t-PA-resistant occlusions in ischemic stroke in miceIn: Blood , Vol. 127 2016, Nr. 19, pp. 2337 – 2345
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Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cellsIn: Nature Communications , Vol. 7 2016, pp. 11626DOI (Open Access)
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Prothrombin and factor X are elevated in multiple sclerosis patientsIn: Annals of Neurology , Vol. 80 2016, Nr. 6, pp. 946 – 951
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Targeting coagulation factor XII as a novel therapeutic option in brain traumaIn: Annals of Neurology , Vol. 79 2016, Nr. 6, pp. 970 – 982DOI (Open Access)