ZMB Member Kathrin Sutter
ZMB Member
Kathrin Sutter
Next Member
PD Dr. Kathrin Sutter
TRR60 Junior Research Group
Interferon-alpha Subtypes in chronic viral infectionsInstitute of Virology
University Hospital Essen
Hufelandstr. 55
45147 Essen
- +49 201 723 83250
- Website
- Publications
- Publication Metrics
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- ZMB Research Program
Immunology, Infectious Diseases and Transplantation
Research Overview
- Interferon-alpha subtypes
- Modulation of immune cells
- Immunotherapies
- Chronic viral infections (HIV, HBV)
- IFN-stimulated genes
- NK cells
Publications
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Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infectionIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 119 (2022) Nr. 8,
ISSN: 1091-6490; 0027-8424Online Full Text: dx.doi.org/ (Open Access) -
Distinct effects of treatment with two different interferon-alpha subtypes on HIV-1-associated T-cell activation and dysfunction in humanized miceIn: AIDS Vol. 36 (2022) Nr. 3, pp. 325 - 336
ISSN: 0269-9370; 1473-5571Online Full Text: dx.doi.org/ -
Immunotherapy With Interferon α11, But Not Interferon Beta, Controls Persistent Retroviral InfectionIn: Frontiers in Immunology Vol. 12 (2022)
ISSN: 1664-3224Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
The Role of the Inhibitory Ligand HVEM and Its Receptors CD160 and BTLA in the Regulation of Anti-retroviral T Cell ResponsesIn: Frontiers in Virology Vol. 2 (2022)
ISSN: 2673-818XOnline Full Text: dx.doi.org/ (Open Access) -
Analysis of the long-term impact on cellular immunity in COVID-19-recovered individuals reveals a profound nkt cell impairmentIn: mBio Vol. 12 (2021) Nr. 2, pp. e00085 - 21
ISSN: 2150-7511; 2161-2129Online Full Text: dx.doi.org/ (Open Access) -
Characterization of SARS-CoV-2-Specific Humoral and Cellular Immune Responses Induced by Inactivated COVID-19 Vaccines in a Real-World SettingIn: Frontiers in Immunology Vol. 12 (2021)
ISSN: 1664-3224Online Full Text: dx.doi.org/ (Open Access) -
Functional Comparison of Interferon-α Subtypes Reveals Potent Hepatitis B Virus Suppression by a Concerted Action of Interferon-α and Interferon-γ SignalingIn: Hepatology Vol. 73 (2021) Nr. 2, pp. 486 - 502
ISSN: 1527-3350; 0270-9139Online Full Text: dx.doi.org/ -
Longitudinal characterization of phenotypic profile of T cells in chronic hepatitis B identifies immune markers associated with HBsAg lossIn: EBioMedicine Vol. 69 (2021)
ISSN: 2352-3964Online Full Text: dx.doi.org/ (Open Access) -
A Crowned Killer’s Résumé : Genome, Structure, Receptors, and Origin of SARS-CoV-2In: Virologica Sinica (2020)
ISSN: 1995-820X; 1674-0769Online Full Text: dx.doi.org/ (Open Access) -
Die Einmischer: Interferone : Wie sie die Immunantwort beeinflussen, um Viren effektiv zu bekämpfenIn: Unikate: Berichte aus Forschung und Lehre (2020) Nr. 54: Medizin: Infektionskrankheiten - ein globales Problem, pp. 18 - 27
ISSN: 0941-746XOnline Full Text: dx.doi.org/ Online Full Text (Open Access) -
Erratum for Westmeier et al., "Impaired Cytotoxic CD8⁺ T Cell Response in Elderly COVID-19 Patients"In: mBio Vol. 11 (2020) Nr. 5, pp. 02243 - 02220
ISSN: 2150-7511; 2161-2129Online Full Text: dx.doi.org/ (Open Access) -
HIV infection does not alter interferon α/β receptor 2 expression on mucosal immune cellsIn: PLoS ONE Vol. 15 (2020) Nr. 1, pp. e0218905
ISSN: 1932-6203Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Impaired cytotoxic CD8⁺ T cell response in elderly COVID-19 patientsIn: mBio Vol. 11 (2020) Nr. 5, pp. e02243 - 20
ISSN: 2150-7511; 2161-2129Online Full Text: dx.doi.org/ (Open Access) -
Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoVIn: Journal of Medical Virology Vol. 92 (2020) Nr. 5, pp. 491 - 494
ISSN: 1096-9071; 0146-6615Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Qualitative differences between the IFNα subtypes and IFNβ influence chronic mucosal HIV-1 pathogenesisIn: PLoS Pathogens Vol. 16 (2020) Nr. 10, pp. 1008986
ISSN: 1553-7374; 1553-7366Online Full Text: dx.doi.org/ (Open Access) -
SERINC5 Is an Unconventional HIV Restriction Factor That Is Upregulated during Myeloid Cell DifferentiationIn: Journal of Innate Immunity Vol. 12 (2020) Nr. 5, pp. 399 - 409
ISSN: 1662-8128; 1662-811XOnline Full Text: dx.doi.org/ (Open Access) -
Susceptibility of SARS-CoV-2 to UV irradiationIn: American Journal of Infection Control Vol. 48 (2020) Nr. 10, pp. 1273 - 1275
ISSN: 1527-3296; 0196-6553Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Antiviral potential of human IFN-α subtypes against influenza A H3N2 infection in human lung explants reveals subtype-specific activitiesIn: Emerging Microbes & Infections Vol. 8 (2019) Nr. 1, pp. 1763 - 1776
ISSN: 2222-1751Online Full Text: dx.doi.org/ (Open Access) -
Characterization of Endogenous SERINC5 Protein as Anti-HIV-1 FactorIn: Journal of Virology Vol. 93 (2019) Nr. 24, pp. e01221 - 19
ISSN: 1098-5514; 0022-538XOnline Full Text: dx.doi.org/ (Open Access) -
Chronic retroviral infection of mice promotes tumor development, but CD137 agonist therapy restores effective tumor immune surveillanceIn: Cancer Immunology, Immunotherapy Vol. 68 (2019) Nr. 3, pp. 479 - 488
ISSN: 1432-0851; 0340-7004Online Full Text: dx.doi.org/ -
Concurrent administration of IFNα14 and cART in TKO-BLT mice enhances suppression of HIV-1 viremia but does not eliminate the latent reservoirIn: Scientific Reports Vol. 9 (2019) pp. 18089
ISSN: 2045-2322Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Different Biological Activities of Specific Interferon Alpha SubtypesIn: mSphere Vol. 4 (2019) Nr. 4, pp. e00127 - 19
ISSN: 2379-5042Online Full Text: dx.doi.org/ (Open Access) -
Diverse immunomodulatory effects of individual IFNα subtypes on virus-specific CD8⁺ T cell responsesIn: Frontiers in Immunology Vol. 10 (2019) pp. 2255
ISSN: 1664-3224Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Friend retrovirus studies reveal complex interactions between intrinsic, innate and adaptive immunityIn: FEMS Microbiology Reviews Vol. 43 (2019) Nr. 5, pp. 435 - 456
ISSN: 1574-6976; 0168-6445Online Full Text: dx.doi.org/ -
Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope ProteinsIn: Cell Reports Vol. 27 (2019) Nr. 7, pp. 2092 - 2104.e10
ISSN: 2211-1247Online Full Text: dx.doi.org/ (Open Access) -
PASylated interferon α efficiently suppresses hepatitis B virus and induces anti-HBs seroconversion in HBV-transgenic miceIn: Antiviral Research Vol. 161 (2019) pp. 134 - 143
ISSN: 1872-9096; 0166-3542Online Full Text: dx.doi.org/ -
Plasmacytoid dendritic cells respond to Epstein-Barr virus infection with a distinct type I interferon subtype profileIn: Blood Advances Vol. 3 (2019) Nr. 7, pp. 1129 - 1144
ISSN: 2473-9537; 2473-9529Online Full Text: dx.doi.org/ (Open Access) -
An advanced BLT-humanized mouse model for extended HIV-1 cure studiesIn: AIDS Vol. 32 (2018) Nr. 1, pp. 1 - 10
ISSN: 1473-5571; 0269-9370Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Hepatitis B virus sensitivity to interferon-α in hepatocytes is more associated with cellular interferon response than with viral genotypeIn: Hepatology Vol. 67 (2018) Nr. 4, pp. 1237 - 1252
ISSN: 1527-3350; 0270-9139Online Full Text: dx.doi.org/ (Open Access) -
Impact of immune suppressive agents on the BK-Polyomavirus non coding control regionIn: Antiviral Research Vol. 159 (2018) pp. 68 - 76
ISSN: 1872-9096; 0166-3542Online Full Text: dx.doi.org/ -
Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8+ T Cell Responses During Chronic Retroviral InfectionIn: Frontiers in Immunology Vol. 9 (2018)
ISSN: 1664-3224Online Full Text: dx.doi.org/ (Open Access) -
Interferon α subtypes in HIV infectionIn: Cytokine & Growth Factor Reviews Vol. 40 (2018) pp. 13 - 18
ISSN: 1359-6101; 1359-6101Online Full Text: dx.doi.org/ -
Different antiviral effects of IFNα and IFNβ in an HBV mouse modelIn: Immunobiology Vol. 222 (2017) Nr. 3, pp. 562 - 570
ISSN: 0171-2985; 1878-3279Online Full Text: dx.doi.org/ -
Different antiviral effects of IFNα subtypes in a mouse model of HBV infectionIn: Scientific Reports Vol. 7 (2017) Nr. 1, pp. 334
ISSN: 2045-2322Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Expression pattern of individual IFNA subtypes in chronic HIV infectionIn: Journal of Interferon & Cytokine Research Vol. 37 (2017) Nr. 12, pp. 541 - 549
ISSN: 1079-9907; 1557-7465Online Full Text: dx.doi.org/ -
Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infectionIn: Scientific Reports Vol. 7 (2017) pp. 7785
ISSN: 2045-2322Online Full Text: dx.doi.org/ (Open Access) -
Human pDCs display sex-specific differences in type I interferon subtypes and interferon α/β receptor expressionIn: European Journal of Immunology Vol. 47 (2017) Nr. 2, pp. 251 - 256
ISSN: 1521-4141; 0014-2980Online Full Text: dx.doi.org/ -
Hypoxia-inducible factor 1α is essential for macrophage-mediated erythroblast proliferation in acute friend retrovirus infectionIn: Scientific Reports Vol. 7 (2017) art. no. 17236
ISSN: 2045-2322Online Full Text: dx.doi.org/ (Open Access) -
Inhibition of catecholamine degradation ameliorates while chemical sympathectomy aggravates the severity of acute Friend retrovirus infection in miceIn: Brain, Behavior and Immunity Vol. 54 (2016) pp. 252 - 259
ISSN: 0889-1591; 1090-2139Online Full Text: dx.doi.org/ -
Insufficient natural killer cell responses against retroviruses : How to improve NK cell killing of retrovirus-infected cellsIn: Retrovirology Vol. 13 (2016) Nr. 1,
ISSN: 1742-4690Online Full Text: dx.doi.org/ (Open Access) -
Interferon alpha subtype-specific suppression of HIV-1 infection in vivoIn: Journal of Virology Vol. 90 (2016) Nr. 13, pp. 6001 - 6013
ISSN: 1098-5514; 0022-538XOnline Full Text: dx.doi.org/ (Open Access) -
TLR ligand induced IL-6 counter-regulates the anti-viral CD8+ T cell response during an acute retrovirus infectionIn: Scientific Reports Vol. 5 (2015) pp. 10501
ISSN: 2045-2322Online Full Text: dx.doi.org/ Online Full Text (Open Access) -
Chemical modifications on siRNAs avoid Toll-like-receptor-mediated activation of the hepatic immune system in vivo and in vitroIn: International Immunology Vol. 26 (2014) Nr. 1, pp. 35 - 46
ISSN: 0953-8178; 1460-2377Online Full Text: dx.doi.org/