ZMB Member Stefanie Flohé

ZMB Member
Stefanie Flohé

Next ZMB-Member
Stefanie Flohe portrait
© UKE

Prof. Dr. Stefanie Flohé

Group

Immunology Sepsis/Trauma

Clinic for Trauma, Hand and Reconstructive Surgery
University Hospital Essen
Hufelandstraße 55
45122 Essen

Research Overview

Pathogenesis of immunosuppression in sepsis
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Selected Publications

    Journal articles

  • Antoni, Anne-Charlotte; Pylaeva, Ekaterina; Budeus, Bettina; Jablonska, Jadwiga; Klein-Hitpaß, Ludger; Dudda, Marcel; Flohé, Stefanie B.
    TLR2-induced CD8⁺ T-cell deactivation shapes dendritic cell differentiation in the bone marrow during sepsis
    In: Frontiers in Immunology, Vol. 13, 2022, 945409
    DOI (Open Access)
  • Bösken, Björn; Hepner-Schefczyk, Monika; Vonderhagen, Sonja; Dudda, Marcel; Flohe, Stefanie
    An Inverse Relationship Between c-Kit/CD117 and mTOR Confers NK Cell Dysregulation Late After Severe Injury
    In: Frontiers in Immunology, Vol. 11, 2020, pp. 1200
    DOI, Online Full Text (Open Access)
  • Rubio, Ignacio; Osuchowski, Marcin F; Shankar-Hari, Manu; Skirecki, Tomasz; Winkler, Martin Sebastian; Lachmann, Gunnar; La Rosée, Paul; Monneret, Guillaume; Venet, Fabienne; Bauer, Michael; Brunkhorst, Frank M; Kox, Matthijs; Cavaillon, Jean-Marc; Uhle, Florian; Weigand, Markus A; Flohe, Stefanie; Wiersinga, W Joost; Martin-Fernandez, Marta; Almansa, Raquel; Martin-Loeches, Ignacio; Torres, Antoni; Giamarellos-Bourboulis, Evangelos J; Girardis, Massimo; Cossarizza, Andrea; Netea, Mihai G; van der Poll, Tom; Scherag, Andre; Meisel, Christian; Schefold, Joerg C; Bermejo-Martín, Jesús F
    Current gaps in sepsis immunology: new opportunities for translational research
    In: The Lancet Infectious Diseases, Vol. 19, 2019, Nr. 12, pp. e422 – e436
    DOI (Open Access)
  • Petri, Robert Michael; Hackel, Alexander; Hahnel, Katrin; Dumitru, Claudia Alexandra; Bruderek, Kirsten; Flohe, Stefanie; Paschen, Annette; Lang, Stephan; Brandau, Sven
    Activated Tissue-Resident Mesenchymal Stromal Cells Regulate Natural Killer Cell Immune and Tissue-Regenerative Function
    In: Stem Cell Reports, Vol. 9, 2017, Nr. 3, pp. 985 – 998
    DOI (Open Access)
  • Smirnov, Anna; Pohlmann, Stephanie; Nehring, Melanie; Ali, Shafaqat; Mann-Nüttel, Ritu; Scheu, Stefanie; Antoni, Anne-Charlotte; Hansen, Wiebke; Büettner, Manuela; Gardiasch, Miriam J.; Westendorf, Astrid; Wirsdörfer, Florian; Pastille, Eva; Dudda, Marcel; Flohe, Stefanie
    Sphingosine 1-Phosphate- and C-C Chemokine Receptor 2-Dependent Activation of CD4+ Plasmacytoid Dendritic Cells in the Bone Marrow Contributes to Signs of Sepsis-Induced Immunosuppression
    In: Frontiers in Immunology, Vol. 8, 2017, 1622
    DOI (Open Access)
  • Wirsdörfer, Florian; Bangen, Jörg-Martin; Pastille, Eva; Hansen, Wiebke; Flohe, Stefanie
    Breaking the co-operation between bystander T-cells and natural killer cells prevents the development of immunosuppression after traumatic skeletal muscle injury in mice
    In: Clinical Science, Vol. 128, 2015, Nr. 11, pp. 825 – 838
    DOI (Open Access)
  • Austermann, Judith; Friesenhagen, Judith; Fassl, Selina Kathleen; Petersen, Beatrix; Ortkras, Theresa; Burgmann, Johanna; Barczyk-Kahlert, Katarzyna; Faist, Eugen; Zedler, Siegfried; Pirr, Sabine; Rohde, Christian; Müller-Tidow, Carsten; vonKöckritz-Blickwede, Maren; vonKaisenberg, Constantin S.; Flohe, Stefanie; Ulas, Thomas; Schultze, Joachim L.; Roth, Johannes; Vogl, Thomas; Viemann, Dorothee; Fassl, Selina Kathleen; von Köckritz-Blickwede, Maren; von Kaisenberg, Constantin S.; Flohé, Stefanie B.; Schultze, Joachim L.
    Erratum: Alarmins MRP8 and MRP14 Induce Stress Tolerance in Phagocytes under Sterile Inflammatory Conditions
    In: Cell Reports, Vol. 11, 2015, Nr. 5, pp. 849
    DOI
  • Austermann, Judith; Friesenhagen, Judith; Fassl, Selina Kathleen; Ortkras, Theresa; Burgmann, Johanna; Barczyk-Kahlert, Katarzyna; Faist, Eugen; Zedler, Siegfried; Pirr, Sabine; Rohde, Christian; Müller-Tidow, Carsten; von Köckritz-Blickwede, Maren; von Kaisenberg, Constantin S; Flohe, Stefanie; Ulas, Thomas; Schultze, Joachim L; Roth, Johannes; Vogl, Thomas; Viemann, Dorothee
    Alarmins MRP8 and MRP14 Induce Stress Tolerance in Phagocytes under Sterile Inflammatory Conditions
    In: Cell Reports, Vol. 9, 2014, Nr. 6, pp. 2112 – 2123
    DOI (Open Access)
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