ZMB Member Astrid Westendorf
ZMB Member
Astrid Westendorf
Next ZMB-Member
Prof. Dr. Astrid Westendorf
Group
Infection ImmunologyInstitute of Medical Microbiology
University Hospital Essen
Hufelandstr. 55
45147 Essen
- +49 201 723 1826
- Website
- Press Releases
- Selected Publications
- Publication Metrics
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- ZMB Research Program
Immunology, Infectious Diseases and Transplantation
Research Overview
- Role of interleukin-33 during intestinal Citrobacter rodentium infection
- Modulation of the mucosal immune system for the treatment of chronic inflammatory bowel diseases
- Importance of immune cells in the induction and rejection of colitis-mediated colon cancer
- Influence of helminth infection on the course of colitis-related colon cancer
- Role of sphingolipids in inflammatory bowel disease
- Development of new nanoparticle-based strategies for modulating the immune system
Selected Publications
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Barium sulphate microparticles are taken up by three different cell types: HeLa, THP-1, and hMSCIn: Acta Biomaterialia , Vol. 164 2023, pp. 577 – 587
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GPR15 facilitates recruitment of regulatory T cells to promote colorectal cancerIn: Cancer Research , Vol. 81 2021, Nr. 11, pp. 2970 – 2982DOI (Open Access)
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Depletion of Foxp3⁺ regulatory T cells is accompanied by an increase in the relative abundance of Firmicutes in the murine gut microbiomeIn: Immunology , Vol. 159 2020, Nr. 3, pp. 344 – 353DOI (Open Access)
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In vivo biodistribution of calcium phosphate nanoparticles after intravascular, intramuscular, intratumoral, and soft tissue administration in mice investigated by small animal PET/CTIn: Acta Biomaterialia , Vol. 109 2020, pp. 244 – 253
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A network of trans-cortical capillaries as mainstay for blood circulation in long bonesIn: Nature Metabolism , Vol. 1 2019, Nr. 2, pp. 236 – 250DOI (Open Access)
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A systematic electron microscopic study on the uptake of barium sulphate nano-, submicro-, microparticles by bone marrow-derived phagocytosing cellsIn: Acta Biomaterialia , Vol. 80 2018, pp. 352 – 363
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CEACAM1 promotes CD8⁺ T cell responses and improves control of a chronic viral infectionIn: Nature Communications , Vol. 9 2018, 2561DOI (Open Access)
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Acquired IFNγ 3 resistance impairs anti-Tumor immunity and gives rise to T-cell-resistant melanoma lesionsIn: Nature Communications , Vol. 8 2017, 15440DOI (Open Access)
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Avidin-conjugated calcium phosphate nanoparticles as a modular targeting system for the attachment of biotinylated molecules in vitro and in vivoIn: Acta Biomaterialia , Vol. 57 2017, pp. 414 – 425
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Delivery of the TLR ligand poly(I:C) to liver cells in vitro and in vivo by calcium phosphate nanoparticles leads to a pronounced immunostimulationIn: Acta Biomaterialia , Vol. 64 2017, pp. 401 – 410
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Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung FibrosisIn: Cancer Research , Vol. 76 2016, Nr. 10, pp. 3045 – 3056DOI (Open Access)
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Plasmodium yoelii infection of BALB/c mice results in expansion rather than induction of CD4+ Foxp3+ regulatory T cellsIn: Immunology , Vol. 148 2016, Nr. 2, pp. 197 – 205DOI (Open Access)
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CEACAM1 induces B-cell survival and is essential for protective antiviral antibody productionIn: Nature Communications , Vol. 6 2015, 6217DOI (Open Access)
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Relevance of Foxp3+ regulatory T cells for early and late phases of murine sepsisIn: Immunology , Vol. 146 2015, Nr. 1, pp. 144 – 156DOI (Open Access)
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Transient ablation of regulatory T cells improves antitumor immunity in colitis-associated colon cancerIn: Cancer Research , Vol. 74 2014, Nr. 16, pp. 4258 – 4269
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Mechanism of the uptake of cationic and anionic calcium phosphate nanoparticles by cellsIn: Acta Biomaterialia , Vol. 9 2013, Nr. 7, pp. 7527 – 7535
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Generation and function of immunosuppressive human and murine CD8⁺ T cells by transforming growth factor-β and retinoic acidIn: Immunology , Vol. 134 2011, Nr. 1, pp. 82 – 92DOI (Open Access)
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Quantitative determination of the composition of multi-shell calcium phosphate-oligonucleotide nanoparticles and their application for the activation of dendritic cellsIn: Acta Biomaterialia , Vol. 7 2011, Nr. 11, pp. 4029 – 4036
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The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxinsIn: Nature , Vol. 453 2008, Nr. 7191, pp. 106 – 109DOI (Open Access)