Prof. Dr. Leo Kiss

Center of Medical Biotechnology (ZMB)
Faculty of Biology
University of Duisburg-Essen
Universitätsstr. 2
45141 Essen

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• +49 201 183 4640 (ZMB Office)
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• ZMB Research Program
  Molecular and Chemical Cell Biology

Research Overview

We are excited about ubiquitin chains and how they organize complex cellular processes, including protein degradation — one of the most fundamental processes in cell biology. Our research will decode the information encoded in ubiquitin chains. To achieve this, we use a cellular biochemistry approach, by combining the biochemical synthesis of ubiquitinated proteins with their intracellular delivery and monitoring. This will enable us to define the intracellular roles of ubiquitin chains, identify ubiquitin chain interaction partners and elucidate the underlying molecular mechanisms.
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