ZMB Member Stefan Raunser

ZMB Member
Stefan Raunser

Next ZMB-Member
portrait photo of ZMB member Stefan Raunser
© MPI/Raunser

Prof. Dr. Stefan Raunser

Group

Structural Biochemistry

Max Planck Institute of Molecular Physiology
Otto-Hahn-Str. 11
44227 Dortmund

Research Overview

  • Structural and functional studies of toxin-mediated membrane permeation
  • Actin cytoskeleton and muscle research
  • High-resolution structures of muscle proteins in situ
  • Cryo electron microscopy (cryo-EM) and cryo electron tomography (cryo-ET)
  • Development of cryo-EM methods and software

Read more

Selected Publications

    Journal articles

  • Wagner, Thorsten; Raunser, Stefan
    Cryo-electron tomography : Challenges and computational strategies for particle picking
    In: Current Opinion in Structural Biology, Vol. 93, 2025, 103113
    DOI (Open Access)
  • Ng’ang’a, Peter Njenga; Folz, Julian; Kucher, Svetlana; Roderer, Daniel; Xu, Ying; Sitsel, Oleg; Belyy, Alexander; Prumbaum, Daniel; Kühnemuth, Ralf; Assafa, Tufa E.; Dong, Min; Seidel, Claus A.M.; Bordignon, Enrica; Raunser, Stefan
    Multistate kinetics of the syringe-like injection mechanism of Tc toxins
    In: Science Advances, Vol. 11, 2025, Nr. 1, eadr2019
    DOI (Open Access)
  • Rodier, Clement; Estabrook, Ian D.; Chan, Eunice HoYee; Rice, Gavin; Loreau, Vincent; Raunser, Stefan; Görlich, Dirk; Friedrich, Benjamin M.; Schnorrer, Frank
    Muscle growth by sarcomere divisions
    In: Science Advances, Vol. 11, 2025, Nr. 28, eadw9445
    DOI (Open Access)
  • Manik, Mohammad K.; Pan, Mengqi; Xiao, Le; Gu, Weixi; Kim, Hyoyoung; Pospich, Sabrina; Hedger, Andrew; Vajjhala, Parimala R.; Lee, Morris Y.L.; Qian, Xiaoqi; Landsberg, Michael J.; Ve, Thomas; Nanson, Jeffrey D.; Raunser, Stefan; Stacey, Katryn J.; Wu, Hao; Kobe, Bostjan
    Structural basis for TIR domain–mediated innate immune signaling by Toll-like receptor adaptors TRIF and TRAM
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 122, 2025, Nr. 2, e2418988122
    DOI (Open Access)
  • Oosterheert, Wout; Boiero Sanders, Micaela; Bieling, Peter; Raunser, Stefan
    Structural insights into actin filament turnover
    In: Trends in Cell Biology, Vol. 35, 2025, Nr. 10, pp. 893 – 906
    DOI (Open Access)
  • Redhardt, Milena; Raunser, Stefan; Raisch, Tobias
    Cryo-EM structure of the Slo1 potassium channel with the auxiliary γ1 subunit suggests a mechanism for depolarization-independent activation
    In: FEBS Letters, Vol. 598, 2024, Nr. 8, pp. 875 – 888
    DOI (Open Access)
  • Oosterheert, Wout; Sanders, Micaela Boiero; Funk, Johanna; Prumbaum, Daniel; Raunser, Stefan; Bieling, Peter
    Molecular mechanism of actin filament elongation by formins
    In: Science, Vol. 384, 2024, Nr. 6692
    DOI
  • Boiero Sanders, Micaela; Oosterheert, Wout; Hofnagel, Oliver; Bieling, Peter; Raunser, Stefan
    Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly
    In: Nature Communications, Vol. 15, 2024, Nr. 1, 7969
    DOI (Open Access)
  • Polley, Soumitra; Raisch, Tobias; Ghetti, Sabrina; Körner, Marie; Terbeck, Melina; Gräter, Frauke; Raunser, Stefan; Aponte-Santamaría, Camilo; Vetter, Ingrid R.; Musacchio, Andrea
    Structure of the human KMN complex and implications for regulation of its assembly
    In: Nature Structural & Molecular Biology, Vol. 31, 2024, Nr. 6, pp. 861 – 873
    DOI (Open Access)
  • Sitsel, Oleg; Wang, Zhexin; Janning, Petra; Kroczek, Lara; Wagner, Thorsten; Raunser, Stefan
    Yersinia entomophaga Tc toxin is released by T10SS-dependent lysis of specialized cell subpopulations
    In: Nature Microbiology, Vol. 9, 2024, Nr. 2, pp. 390 – 404
    DOI (Open Access)
  • Wieferig, Jan-Philip; Kühlbrandt, Werner; Raunser, Stefan
    Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III2 by cryo-EM
    In: IUCrJ, Vol. 10, 2023, pp. 27 – 37
    DOI (Open Access)
  • Bürgi, Jérôme; Lill, Pascal; Giannopoulou, Evdokia-Anastasia; Jeffries, Cy M.; Chojnowski, Grzegorz; Raunser, Stefan; Gatsogiannis, Christos; Wilmanns, Matthias
    Asymmetric horseshoe-like assembly of peroxisomal yeast oxalyl-CoA synthetase
    In: Biological Chemistry, Vol. 404, 2023, Nr. 2-3, pp. 195 – 207
    DOI (Open Access)
  • Oosterheert, Wout; Blanc, Florian E. C.; Roy, Ankit; Belyy, Alexander; Sanders, Micaela Boiero; Hofnagel, Oliver; Hummer, Gerhard; Bieling, Peter; Raunser, Stefan
    Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments
    In: Nature Structural & Molecular Biology, Vol. 30, 2023, Nr. 11, pp. 1774 – 1785
    DOI (Open Access)
  • Wang, Zhexin; Raunser, Stefan
    Structural Biochemistry of Muscle Contraction
    In: Annual Review of Biochemistry, Vol. 92, 2023, pp. 411 – 433
    DOI (Open Access)
  • Quentin, Dennis; Schuhmacher, Jan S.; Klink, Björn U.; Lauer, Jeni; Shaikh, Tanvir R.; Huis in ’t Veld, Pim J.; Welp, Luisa M.; Urlaub, Henning; Zerial, Marino; Raunser, Stefan
    Structural basis of mRNA binding by the human FERRY Rab5 effector complex
    In: Molecular Cell, Vol. 83, 2023, Nr. 11, pp. 1856 – 1871.e9
    DOI (Open Access)
  • Belyy, Alexander; Heilen, Philipp; Hagel, Philine; Hofnagel, Oliver; Raunser, Stefan
    Structure and activation mechanism of the Makes caterpillars floppy 1 toxin
    In: Nature Communications, Vol. 14, 2023, Nr. 1, 8226
    DOI (Open Access)
  • Tamborrini, Davide; Wang, Zhexin; Wagner, Thorsten; Tacke, Sebastian; Stabrin, Markus; Grange, Michael; Kho, Ay Lin; Rees, Martin; Bennett, Pauline; Gautel, Mathias; Raunser, Stefan
    Structure of the native myosin filament in the relaxed cardiac sarcomere
    In: Nature, Vol. 623, 2023, Nr. 7988, pp. 863 – 871
    DOI (Open Access)
  • Raisch, Tobias; Raunser, Stefan
    The modes of action of ion-channel-targeting neurotoxic insecticides: lessons from structural biology
    In: Nature Structural & Molecular Biology, Vol. 30, 2023, Nr. 10, pp. 1411 – 1427
    DOI
  • Rice, Gavin; Wagner, Thorsten; Stabrin, Markus; Sitsel, Oleg; Prumbaum, Daniel; Raunser, Stefan
    TomoTwin : generalized 3D localization of macromolecules in cryo-electron tomograms with structural data mining
    In: Nature Methods, Vol. 20, 2023, Nr. 6, pp. 871 – 880
    DOI (Open Access)
  • Boltje, Daan B.; Hoogenboom, Jacob P.; Jakobi, Arjen J.; Jensen, Grant J.; Jonker, Caspar T. H.; Kaag, Max J.; Koster, Abraham J.; Last, Mart G. F.; Pinto, Cecilia de Agrela; Plitzko, Jürgen M.; Raunser, Stefan; Tacke, Sebastian; Wang, Zhexin; van der Wee, Ernest B.; Wepf, Roger; Hoedt, Sander Den
    A cryogenic, coincident fluorescence, electron, and ion beam microscope
    In: eLife, Vol. 11, 2022, e82891
    DOI (Open Access)
  • Schöenfeld, Fabian; Stabrin, Markus; Shaikh, Tanvir R.; Wagner, Thorsten; Raunser, Stefan
    Accelerated 2D Classification With ISAC Using GPUs
    In: Frontiers in Molecular Biosciences, Vol. 9, 2022, 919994
    DOI (Open Access)
  • Xu, Ying; Viswanatha, Raghuvir; Sitsel, Oleg; Roderer, Daniel; Zhao, Haifang; Ashwood, Christopher; Voelcker, Cecilia; Tian, Songhai; Raunser, Stefan; Perrimon, Norbert; Dong, Min
    CRISPR screens in Drosophila cells identify Vsg as a Tc toxin receptor
    In: Nature, Vol. 610, 2022, Nr. 7931, pp. 349 – 355
    DOI, Online Full Text (Open Access)
  • Belyy, Alexander; Lindemann, Florian; Roderer, Daniel; Funk, Johanna; Bardiaux, Benjamin; Protze, Jonas; Bieling, Peter; Oschkinat, Hartmut; Raunser, Stefan
    Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin
    In: Nature Communications, Vol. 13, 2022, Nr. 1, 4202
    DOI
  • Urlaub, Doris; Wolfsdorff, Natalie; Hoffmann, Jan-Erik; Dorok, Stefanie; Hoffmann, Markus; Anft, Moritz; Pieris, Naomi; Günther, Patrick; Schaaf, Bernhard; Cassens, Uwe; Bröde, Peter; Claus, Maren; Picard, Lea K.; Wingert, Sabine; Backes, Simone; Durak, Deniz; Babel, Nina; Pöhlmann, Stefan; Renken, Frank; Raunser, Stefan; Watzl, Carsten
    Neutralizing antibody responses 300 days after SARS-CoV-2 infection and induction of high antibody titers after vaccination
    In: European Journal of Immunology, Vol. 52, 2022, Nr. 5, pp. 810 – 815
    DOI (Open Access)
  • Wagner, Thorsten; Raunser, Stefan
    Recent developments in automated single-particle selection
    In: Nature Reviews Methods Primers, Vol. 2, 2022, Nr. 1, 16
    DOI
  • Oosterheert, Wout; Klink, Björn U.; Belyy, Alexander; Pospich, Sabrina; Raunser, Stefan
    Structural basis of actin filament assembly and aging
    In: Nature, Vol. 611, 2022, Nr. 7935, pp. 374 – 379
    DOI (Open Access)
  • Günther, Patrick; Quentin, Dennis; Ahmad, Shehryar; Sachar, Kartik; Gatsogiannis, Christos; Whitney, John C.; Raunser, Stefan
    Structure of a bacterial Rhs effector exported by the type VI secretion system
    In: PLoS Pathogens, Vol. 18, 2022, Nr. 1, e1010182
    DOI (Open Access)
  • Klink, Björn U.; Herrmann, Eric; Antoni, Claudia; Langemeyer, Lars; Kiontke, Stephan; Gatsogiannis, Christos; Ungermann, Christian; Raunser, Stefan; Kümmel, Daniel
    Structure of the Mon1-Ccz1 complex reveals molecular basis of membrane binding for Rab7 activation
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 119, 2022, Nr. 6, e2121494119
    DOI (Open Access)
  • Raisch, Tobias; Ciossani, Giuseppe; d’Amico, Ennio; Cmentowski, Verena; Carmignani, Sara; Maffini, Stefano; Merino, Felipe; Wohlgemuth, Sabine; Vetter, Ingrid R.; Raunser, Stefan; Musacchio, Andrea
    Structure of the RZZ complex and molecular basis of Spindly‐driven corona assembly at human kinetochores
    In: The EMBO Journal, Vol. 41, 2022, Nr. 9, e110411
    DOI, Online Full Text (Open Access)
  • Pesenti, Marion E.; Raisch, Tobias; Conti, Duccio; Walstein, Kai; Hoffmann, Ingrid; Vogt, Dorothee; Prumbaum, Daniel; Vetter, Ingrid R.; Raunser, Stefan; Musacchio, Andrea
    Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization
    In: Molecular Cell, Vol. 82, 2022, Nr. 11, pp. 2113 – 2131.e8
    DOI (Open Access)
  • Wang, Zhexin; Grange, Michael; Pospich, Sabrina; Wagner, Thorsten; Kho, Ay Lin; Gautel, Mathias; Raunser, Stefan
    Structures from intact myofibrils reveal mechanism of thin filament regulation through nebulin
    In: Science, Vol. 375, 2022, Nr. 6582, eabn1934
    DOI, Online Full Text (Open Access)
  • Funk, Johanna; Merino, Felipe; Schaks, Matthias; Rottner, Klemens; Raunser, Stefan; Bieling, Peter
    A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks
    In: Nature Communications, Vol. 12, 2021, Nr. 1, 5329
    DOI (Open Access)
  • Tacke, Sebastian; Erdmann, Philipp; Wang, Zhexin; Klumpe, Sven; Grange, Michael; Plitzko, Jürgen; Raunser, Stefan
    A streamlined workflow for automated cryo focused ion beam milling
    In: Journal of Structural Biology, Vol. 213, 2021, Nr. 3, 107743
    DOI (Open Access)
  • Pospich, Sabrina; Küllmer, Florian; Nasufović, Veselin; Funk, Johanna; Belyy, Alexander; Bieling, Peter; Arndt, Hans-Dieter; Raunser, Stefan
    Cryo-EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States
    In: Angewandte Chemie International Edition, Vol. 60, 2021, Nr. 16, pp. 8678 – 8682
    DOI (Open Access)
  • Schoppe, Jannis; Schubert, Evelyn; Apelbaum, Amir; Yavavli, Erdal; Birkholz, Oliver; Stephanowitz, Heike; Han, Yaping; Perz, Angela; Hofnagel, Oliver; Liu, Fan; Piehler, Jacob; Raunser, Stefan; Ungermann, Christian
    Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi
    In: The Journal of Biological Chemistry (JBC), Vol. 297, 2021, Nr. 5, 101334
    DOI (Open Access)
  • Pospich, Sabrina; Sweeney, H. Lee; Houdusse, Anne; Raunser, Stefan
    High-resolution structures of the actomyosin-v complex in three nucleotide states provide insights into the force generation mechanism
    In: eLife, Vol. 10, 2021, e73724
    DOI (Open Access)
  • Belyy, Alexander; Merino, Felipe; Mechold, Undine; Raunser, Stefan
    Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens
    In: Nature Communications, Vol. 12, 2021, Nr. 1, 6628
    DOI (Open Access)
  • Chen, Minghao; Blum, Daniel; Engelhard, Lena; Raunser, Stefan; Wagner, Richard; Gatsogiannis, Christos
    Molecular architecture of black widow spider neurotoxins
    In: Nature Communications, Vol. 12, 2021, Nr. 1, 6956
    DOI (Open Access)
  • Oliva, Rosario; Mukherjee, Sanjib K.; Ostermeier, Lena; Pazurek, Lilli A.; Kriegler, Simon; Bader, Verian; Prumbaum, Daniel; Raunser, Stefan; Winklhofer, Konstanze F.; Tatzelt, Jörg; Winter, Roland
    Remodeling of the Fibrillation Pathway of α-Synuclein by Interaction with Antimicrobial Peptide LL-III
    In: Chemistry - A European Journal, Vol. 27, 2021, Nr. 46, pp. 11845 – 11851
    DOI (Open Access)
  • Raisch, Tobias; Brockmann, Andreas; Ebbinghaus-Kintscher, Ulrich; Freigang, Jörg; Gutbrod, Oliver; Kubicek, Jan; Maertens, Barbara; Hofnagel, Oliver; Raunser, Stefan
    Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM
    In: Nature Communications, Vol. 12, 2021, Nr. 1, 7164
    DOI (Open Access)
  • Yu, Jun; Raia, Pierre; Ghent, Chloe M.; Raisch, Tobias; Sadian, Yashar; Cavadini, Simone; Sabale, Pramod M.; Barford, David; Raunser, Stefan; Morgan, David O.; Boland, Andreas
    Structural basis of human separase regulation by securin and CDK1–cyclin B1
    In: Nature, Vol. 596, 2021, Nr. 7870, pp. 138 – 142
    DOI, Online Full Text (Open Access)
  • Fitzian, Katharina; Brückner, Anne; Brohée, Laura; Zech, Reinhard; Antoni, Claudia; Kiontke, Stephan; Gasper, Raphael; Linard Matos, Anna Livia; Beel, Stephanie; Wilhelm, Sabine; Gerke, Volker; Ungermann, Christian; Nellist, Mark; Raunser, Stefan; Demetriades, Constantinos; Oeckinghaus, Andrea; Kümmel, Daniel
    TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation
    In: Molecular Cell, Vol. 81, 2021, Nr. 13, pp. 2705 – 2721.e8
    DOI (Open Access)
  • Wang, Zhexin; Grange, Michael; Wagner, Thorsten; Kho, Ay Lin; Gautel, Mathias; Raunser, Stefan
    The molecular basis for sarcomere organization in vertebrate skeletal muscle
    In: Cell, Vol. 184, 2021, Nr. 8, pp. 2135 – 2150.e13
    DOI (Open Access)
  • Klika Škopić, Mateja; Gramse, Christian; Oliva, Rosario; Pospich, Sabrina; Neukirch, Laura; Manisegaran, Magiliny; Raunser, Stefan; Winter, Roland; Weberskirch, Ralf; Brunschweiger, Andreas
    Towards DNA-Encoded Micellar Chemistry : DNA-Micelle Association and Environment Sensitivity of Catalysis
    In: Chemistry - A European Journal, Vol. 27, 2021, Nr. 39, pp. 10048 – 10057
    DOI (Open Access)
  • Antoni, Claudia; Quentin, Dennis; Lang, Alexander E.; Aktories, Klaus; Gatsogiannis, Christos; Raunser, Stefan
    Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state
    In: PLoS Pathogens, Vol. 16, 2020, Nr. 8, e1008530
    DOI (Open Access)
  • Roderer, Daniel; Bröcker, Felix; Sitsel, Oleg; Kaplonek, Paulina; Leidreiter, Franziska; Seeberger, Peter H.; Raunser, Stefan
    Glycan-dependent cell adhesion mechanism of Tc toxins
    In: Nature Communications, Vol. 11, 2020, Nr. 1, 2694
    DOI (Open Access)
  • Pospich, Sabrina; Merino, Felipe; Raunser, Stefan
    Structural Effects and Functional Implications of Phalloidin and Jasplakinolide Binding to Actin Filaments
    In: Structure, Vol. 28, 2020, Nr. 4, pp. 437 – 449.e5
    DOI (Open Access)
  • Ahmad, Shehryar; Tsang, Kara K.; Sachar, Kartik; Quentin, Dennis; Tashin, Tahmid M.; Bullen, Nathan P.; Raunser, Stefan; McArthur, Andrew G.; Prehna, Gerd; Whitney, John C.
    Structural basis for effector transmembrane domain recognition by type vi secretion system chaperones
    In: eLife, Vol. 9, 2020, e62816
    DOI (Open Access)
  • Vinayagam, Deivanayagabarathy; Quentin, Dennis; Yu-Strzelczyk, Jing; Sitsel, Oleg; Merino, Felipe; Stabrin, Markus; Hofnagel, Oliver; Yu, Maolin; Ledeboer, Mark W.; Nagel, Georg; Malojcic, Goran; Raunser, Stefan
    Structural basis of trpc4 regulation by calmodulin and pharmacological agents
    In: eLife, Vol. 9, 2020, pp. 1 – 58
    DOI (Open Access)
  • Belyy, Alexander; Merino, Felipe; Sitsel, Oleg; Raunser, Stefan
    Structure of the Lifeact–F-actin complex
    In: PLoS Biology, Vol. 18, 2020, Nr. 11, e3000925
    DOI (Open Access)
  • Klink, Björn U.; Gatsogiannis, Christos; Hofnagel, Oliver; Wittinghofer, Alfred; Raunser, Stefan
    Structure of the human BBSome core complex
    In: eLife, Vol. 9, 2020, e53910
    DOI (Open Access)
  • Wagner, Thorsten; Raunser, Stefan
    The evolution of SPHIRE-crYOLO particle picking and its application in automated cryo-EM processing workflows
    In: Communications Biology, Vol. 3, 2020, Nr. 1, 61
    DOI (Open Access)
  • Merino, Felipe; Pospich, Sabrina; Raunser, Stefan
    Towards a structural understanding of the remodeling of the actin cytoskeleton
    In: Seminars in Cell and Developmental Biology, Vol. 102, 2020, pp. 51 – 64
    DOI (Open Access)
  • Stabrin, Markus; Schoenfeld, Fabian; Wagner, Thorsten; Pospich, Sabrina; Gatsogiannis, Christos; Raunser, Stefan
    TranSPHIRE : automated and feedback-optimized on-the-fly processing for cryo-EM
    In: Nature Communications, Vol. 11, 2020, Nr. 1, 5716
    DOI (Open Access)
  • Wagner, Thorsten; Lusnig, Luca; Pospich, Sabrina; Stabrin, Markus; Schonfeld, Fabian; Raunser, Stefan
    Two particle-picking procedures for filamentous proteins : SPHIRE-crYOLO filament mode and SPHIRE-STRIPER
    In: Acta Crystallographica Section D: Structural Biology, Vol. 76, 2020, pp. 613 – 620
    DOI (Open Access)
  • Sitsel, Oleg; Raunser, Stefan
    Big insights from tiny crystals
    In: Nature Chemistry, Vol. 11, 2019, Nr. 2, pp. 106 – 108
    DOI
  • Leidreiter, F.; Roderer, D.; Meusch, D.; Gatsogiannis, C.; Benz, R.; Raunser, Stefan
    Common architecture of Tc toxins from human and insect pathogenic bacteria
    In: Science Advances, Vol. 5, 2019, Nr. 10, eaax6497
    DOI (Open Access)
  • Tanaka, Yoshikazu; Kato, Sanae; Stabrin, Markus; Raunser, Stefan; Matsui, Takashi; Gatsogiannis, Christos
    Cryo-EM reveals the asymmetric assembly of squid hemocyanin
    In: IUCrJ, Vol. 6, 2019, pp. 426 – 437
    DOI (Open Access)
  • Gatsogiannis, Christos; Balogh, Dora; Merino, Felipe; Sieber, Stephan A.; Raunser, Stefan
    Cryo-EM structure of the ClpXP protein degradation machinery
    In: Nature Structural & Molecular Biology, Vol. 26, 2019, Nr. 10, pp. 946 – 954
    DOI
  • Roderer, Daniel; Raunser, Stefan
    Giftspritzen mit einzigartigem Injektionsmechanismus
    In: Biospektrum, Vol. 25, 2019, Nr. 5, pp. 500 – 503
    DOI (Open Access)
  • Škopić, M. Klika; Götte, K.; Gramse, C.; Dieter, M.; Pospich, S.; Raunser, Stefan; Weberskirch, R.; Brunschweiger, A.
    Micellar Brønsted Acid Mediated Synthesis of DNA-Tagged Heterocycles
    In: Journal of the American Chemical Society: JACS, Vol. 141, 2019, Nr. 26, pp. 10546 – 10555
    DOI
  • Funk, Johanna; Merino, Felipe; Venkova, Larisa; Heydenreich, Lina; Kierfeld, Jan; Vargas, Pablo; Raunser, Stefan; Piel, Matthieu; Bieling, Peter
    Profilin and formin constitute a pacemaker system for robust actin filament growth
    In: eLife, Vol. 8, 2019, e50963
    DOI (Open Access)
  • Raisch, Tobias; Chang, Chung-Te; Levdansky, Yevgen; Muthukumar, Sowndarya; Raunser, Stefan; Valkov, Eugene
    Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation
    In: Nature Communications, Vol. 10, 2019, Nr. 1, 3173
    DOI (Open Access)
  • Wagner, Thorsten; Merino, Felipe; Stabrin, Markus; Moriya, Toshio; Antoni, Claudia; Apelbaum, Amir; Hagel, Philine; Sitsel, Oleg; Raisch, Tobias; Prumbaum, Daniel; Quentin, Dennis; Roderer, Daniel; Tacke, Sebastian; Siebolds, Birte; Schubert, Evelyn; Shaikh, Tanvir R.; Lill, Pascal; Gatsogiannis, Christos; Raunser, Stefan
    SPHIRE-crYOLO is a fast and accurate fully automated particle picker for cryo-EM
    In: Communications Biology, Vol. 2, 2019, Nr. 1, 218
    DOI (Open Access)
  • Roderer, Daniel; Hofnagel, Oliver; Benz, Roland; Raunser, Stefan
    Structure of a Tc holotoxin pore provides insights into the translocation mechanism
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 116, 2019, Nr. 46, pp. 23083 – 23090
    DOI (Open Access)
  • Roderer, Daniel; Raunser, Stefan
    Tc toxin complexes : Assembly, membrane permeation, and protein translocation
    In: Annual Review of Microbiology, Vol. 73, 2019, pp. 247 – 265
    DOI
  • Roderer, Daniel; Schubert, Evelyn; Sitsel, Oleg; Raunser, Stefan
    Towards the application of Tc toxins as a universal protein translocation system
    In: Nature Communications, Vol. 10, 2019, Nr. 1, 5263
    DOI (Open Access)
  • Yavuz, Halenur; Kattan, Iman; Hernandez, Javier M.; Hofnagel, Oliver; Witkowska, Agata; Raunser, Stefan; Walla, Peter J.; Jahn, Reinhard
    Arrest of trans-SNARE zippering uncovers loosely and tightly docked intermediates in membrane fusion
    In: The Journal of Biological Chemistry (JBC), Vol. 293, 2018, Nr. 22, pp. 8645 – 8655
    DOI (Open Access)
  • Vinayagam, Deivanayagabarathy; Mager, Thomas; Apelbaum, Amir; Bothe, Arne; Merino, Felipe; Hofnagel, Oliver; Gatsogiannis, Christos; Raunser, Stefan
    Electron cryo-microscopy structure of the canonical TRPC4 ion channel
    In: eLife, Vol. 7, 2018, e36615
    DOI (Open Access)
  • Quentin, Dennis; Raunser, Stefan
    Electron cryomicroscopy as a powerful tool in biomedical research
    In: Journal of Molecular Medicine, Vol. 96, 2018, Nr. 6, pp. 483 – 493
    DOI (Open Access)
  • Quentin, Dennis; Ahmad, Shehryar; Shanthamoorthy, Premy; Mougous, Joseph D.; Whitney, John C.; Raunser, Stefan
    Mechanism of loading and translocation of type VI secretion system effector Tse6
    In: Nature Microbiology, Vol. 3, 2018, Nr. 10, pp. 1142 – 1152
    DOI, Online Full Text (Open Access)
  • Schubert, Evelyn; Vetter, Ingrid R.; Prumbaum, Daniel; Penczek, Pawel A.; Raunser, Stefan
    Membrane insertion of α-xenorhabdolysin in near-atomic detail
    In: eLife, Vol. 7, 2018, e38017
    DOI (Open Access)
  • Káčeriková, Radka; Godočíková, Jana; Wang, Zhexin; Kutejová, Eva; Raunser, Stefan; Farkašovský, Marian
    Modulation of septin higher-order structure by the Cdc28 protein kinase
    In: Biologia, Vol. 73, 2018, Nr. 10, pp. 1025 – 1033
    DOI
  • Ludwig, Anna-Kristin; De Miroschedji, Kyra; Döppner, Thorsten R.; Börger, Verena; Ruesing, Johannes; Rebmann, Vera; Durst, Stephan; Jansen, Sören; Bremer, Michel; Behrmann, Elmar; Singer, Bernhard B.; Jastrow, Holger; Kuhlmann, Jan Dominik; El Magraoui, Fouzi; Meyer, Helmut E.; Hermann, Dirk M.; Opalka, Bertram; Raunser, Stefan; Epple, Matthias; Horn, Peter; Giebel, Bernd
    Precipitation with polyethylene glycol followed by washing and pelleting by ultracentrifugation enriches extracellular vesicles from tissue culture supernatants in small and large scales
    In: Journal of Extracellular Vesicles (JEV), Vol. 7, 2018, Nr. 1, pp. 1528109
    DOI (Open Access)
  • Pesenti, Marion E; Prumbaum, Daniel; Auckland, Philip; Smith, Charlotte M; Faesen, Alex C; Petrovic, Arsen; Erent, Muriel; Maffini, Stefano; Pentakota, Satyakrishna; Weir, John R; Lin, Yu-Chih; Raunser, Stefan; McAinsh, Andrew D; Musacchio, Andrea
    Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80.
    In: Molecular Cell, Vol. 71, 2018, Nr. 6, pp. 923 – 939.e10
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  • Pospich, Sabrina; Raunser, Stefan
    Single particle cryo-EM : an optimal tool to study cytoskeletal proteins
    In: Current Opinion in Structural Biology, Vol. 52, 2018, pp. 16 – 24
    DOI
  • Merino, Felipe; Pospich, Sabrina; Funk, Johanna; Wagner, Thorsten; Küllmer, Florian; Arndt, Hans-Dieter; Bieling, Peter; Raunser, Stefan
    Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM /631/535/1258/1259 /631/45/612/1228 /101 /101/28 article
    In: Nature Structural & Molecular Biology, Vol. 25, 2018, Nr. 6, pp. 528 – 537
    DOI
  • Gatsogiannis, Christos; Merino, Felipe; Roderer, Daniel; Balchin, David; Schubert, Evelyn; Kuhlee, Anne; Hayer-Hartl, Manajit; Raunser, Stefan
    Tc toxin activation requires unfolding and refolding of a β-propeller
    In: Nature, Vol. 563, 2018, Nr. 7730, pp. 209 – 233
    DOI
  • Merino, Felipe; Raunser, Stefan
    The complex simplicity of the bacterial cytoskeleton
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 115, 2018, Nr. 13, pp. 3205 – 3206
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  • Klink, Björn Udo; Zent, Eldar; Juneja, Puneet; Kuhlee, Anne; Raunser, Stefan; Wittinghofer, Alfred
    A recombinant BBSome core complex and how it interacts with ciliary cargo
    In: eLife, Vol. 6, 2017, e27434
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  • Kiontke, Stephan; Langemeyer, Lars; Kuhlee, Anne; Schuback, Saskia; Raunser, Stefan; Ungermann, Christian; Kümmel, Daniel
    Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1-Ccz1
    In: Nature Communications, Vol. 8, 2017, 14034
    DOI (Open Access)
  • Raunser, Stefan
    Cryo-EM Revolutionizes the Structure Determination of Biomolecules
    In: Angewandte Chemie International Edition, Vol. 56, 2017, Nr. 52, pp. 16450 – 16452
    DOI
  • Raunser, Stefan
    Eine coole Technik : Kryoelektronenmikroskopie
    In: Nachrichten aus der Chemie, Vol. 65, 2017, Nr. 11, pp. 1086 – 1088
    DOI
  • Merino, Felipe; Raunser, Stefan
    Electron Cryo-microscopy as a Tool for Structure-Based Drug Development
    In: Angewandte Chemie International Edition, Vol. 56, 2017, Nr. 11, pp. 2846 – 2860
    DOI
  • Andersen, Christian Brix Folsted; Stødkilde, Kristian; Sæderup, Kirstine Lindhardt; Kuhlee, Anne; Raunser, Stefan; Graversen, Jonas H.; Moestrup, Søren Kragh
    Haptoglobin
    In: Antioxidants and Redox Signaling, Vol. 26, 2017, Nr. 14, pp. 814 – 831
    DOI
  • Moriya, Toshio; Saur, Michael; Stabrin, Markus; Merino, Felipe; Voicu, Horatiu; Huang, Zhong; Penczek, Pawel A.; Raunser, Stefan; Gatsogiannis, Christos
    High-resolution single particle analysis from electron cryo-microscopy images using SPHIRE
    In: JoVE, Vol. 2017, 2017, Nr. 123, e55448
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  • Lürick, Anna; Gao, Jieqiong; Kuhlee, Anne; Yavavli, Erdal; Langemeyer, Lars; Perz, Angela; Raunser, Stefan; Ungermann, Christian
    Multivalent Rab interactions determine tether-mediated membrane fusion
    In: Molecular Biology of the Cell, Vol. 28, 2017, Nr. 2, pp. 322 – 332
    DOI
  • Pospich, Sabrina; Kumpula, Esa-Pekka; Von Der Ecken, Julian; Vahokoski, Juha; Kursula, Inari; Raunser, Stefan
    Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 114, 2017, Nr. 40, pp. 10636 – 10641
    DOI (Open Access)
  • Purushothaman, Latha Kallur; Arlt, Henning; Kuhlee, Anne; Raunser, Stefan; Ungermann, Christian
    Retromer-driven membrane tubulation separates endosomal recycling from Rab7/Ypt7-dependent fusion
    In: Molecular Biology of the Cell, Vol. 28, 2017, Nr. 6, pp. 783 – 791
    DOI (Open Access)
  • Orekhov, Philipp; Bothe, Arne; Steinhoff, Heinz-Jürgen; Shaitan, Konstantin V.; Raunser, Stefan; Fotiadis, Dimitrios; Schlesinger, Ramona; Klare, Johann P.; Engelhard, Martin
    Sensory Rhodopsin I and Sensory Rhodopsin II Form Trimers of Dimers in Complex with their Cognate Transducers
    In: Photochemistry and Photobiology, Vol. 93, 2017, Nr. 3, pp. 796 – 804
    DOI
  • Chen, Meirong; Kato, Koji; Kubo, Yume; Tanaka, Yoshikazu; Liu, Yuchen; Long, Feng; Whitman, William B.; Lill, Pascal; Gatsogiannis, Christos; Raunser, Stefan; Shimizu, Nobutaka; Shinoda, Akira; Nakamura, Akiyoshi; Tanaka, Isao; Yao, Min
    Structural basis for tRNA-dependent cysteine biosynthesis
    In: Nature Communications, Vol. 8, 2017, Nr. 1, 1521
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  • Mosalaganti, Shyamal; Keller, Jenny; Altenfeld, Anika; Winzker, Michael; Rombaut, Pascaline; Saur, Michael; Petrovic, Arsen; Wehenke, Annemarie; Wohlgemuth, Sabine; Müller, Franziska; Maffini, Stefano; Bange, Tanja; Herzog, Franz; Waldmann, Herbert; Raunser, Stefan; Musacchio, Andrea
    Structure of the RZZ complex and molecular basis of its interaction with Spindly
    In: The Journal of Cell Biology (JCB), Vol. 216, 2017, Nr. 4, pp. 961 – 981
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  • Pospich, Sabrina; Raunser, Stefan
    The molecular basis of Alzheimer’s plaques
    In: Science, Vol. 358, 2017, Nr. 6359, pp. 45 – 46
    DOI
  • Von Der Ecken, Julian; Heissler, Sarah M.; Pathan-Chhatbar, Salma; Manstein, Dietmar J.; Raunser, Stefan
    Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
    In: Nature, Vol. 534, 2016, Nr. 7609, pp. 724 – 728
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  • Liu, Yahui; Petrovic, Arsen; Rombaut, Pascaline; Mosalaganti, Shyamal; Keller, Jenny; Raunser, Stefan; Herzog, Franz; Musacchio, Andrea
    Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogaster
    In: Open Biology, Vol. 6, 2016, Nr. 2, 150236
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  • Gatsogiannis, Christos; Merino, Felipe; Prumbaum, Daniel; Roderer, Daniel; Leidreiter, Franziska; Meusch, Dominic; Raunser, Stefan
    Membrane insertion of a Tc toxin in near-atomic detail
    In: Nature Structural & Molecular Biology, Vol. 23, 2016, Nr. 10, pp. 884 – 890
    DOI (Open Access)
  • Friese, Alexandra; Musacchio, Andrea; Herzog, Franz; Raunser, Stefan; Petrovic, Arsen; Prumbaum, Daniel; Fischböck, Josef; Huis in ‘t Veld,, Pim J.; Faesen, Alex C.
    Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin
    In: Nature Communications, Vol. 7, 2016, pp. 11407
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  • Merino, Felipe; Raunser, Stefan
    The mother of all actins?
    In: eLife, Vol. 5, 2016, e23354
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  • Whitney, John C.; Quentin, Dennis; Sawai, Shin; LeRoux, Michele; Harding, Brittany N.; Ledvina, Hannah E.; Tran, Bao Q.; Robinson, Howard; Goo, Young Ah; Goodlett, David R.; Raunser, Stefan; Mougous, Joseph D.
    An Interbacterial NAD(P)⁺ Glycohydrolase Toxin Requires Elongation Factor Tu for Delivery to Target Cells
    In: Cell, Vol. 163, 2015, Nr. 3, pp. 607 – 619
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  • Efremov, Rouslan G.; Leitner, Alexander; Aebersold, Ruedi; Raunser, Stefan
    Architecture and conformational switch mechanism of the ryanodine receptor
    In: Nature, Vol. 517, 2015, Nr. 7532, pp. 39 – 43
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  • Gao, Mimi; Berghaus, Melanie; von der Ecken, Julian; Raunser, Stefan; Winter, Roland
    Condensation Agents Determine the Temperature–Pressure Stability of F-Actin Bundles
    In: Angewandte Chemie International Edition, Vol. 54, 2015, Nr. 38, pp. 11088 – 11092
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  • Raunser, Stefan; Gatsogiannis, Christos
    Deciphering the tubulin code
    In: Cell, Vol. 161, 2015, Nr. 5, pp. 960 – 961
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  • Poepsel, Simon; Sprengel, Andreas; Sacca, Barbara; Kaschani, Farnusch; Kaiser, Markus; Gatsogiannis, Christos; Raunser, Stefan; Clausen, Tim; Ehrmann, Michael
    Determinants of amyloid fibril degradation by the PDZ protease HTRA1
    In: Nature Chemical Biology, Vol. 11, 2015, Nr. 11, pp. 862 – 869
    DOI, Online Full Text (Open Access)
  • Kuhlee, Anne; Raunser, Stefan; Ungermann, Christian
    Functional homologies in vesicle tethering
    In: FEBS Letters, Vol. 589, 2015, Nr. 19, pp. 2487 – 2497
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  • Frisch, Hendrik; Nie, Yan; Raunser, Stefan; Besenius, Pol
    PH-regulated selectivity in supramolecular polymerizations : Switching between co- And homopolymers
    In: Chemistry - A European Journal, Vol. 21, 2015, Nr. 8, pp. 3304 – 3309
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  • Gatsogiannis, Christos; Hofnagel, Oliver; Markl, Jürgen; Raunser, Stefan
    Structure of mega-hemocyanin reveals protein origami in snails
    In: Structure, Vol. 23, 2015, Nr. 1, pp. 93 – 103
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  • Von Der Ecken, Julian; Müller, Mirco; Lehman, William; Manstein, Dietmar J.; Penczek, Pawel A.; Raunser, Stefan
    Structure of the F-actin-tropomyosin complex
    In: Nature, Vol. 519, 2015, Nr. 7541, pp. 114 – 117
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  • Lürick, Anna; Kuhlee, Anne; Bröcker, Cornelia; Kümmel, Daniel; Raunser, Stefan; Ungermann, Christian
    The Hₐbc domain of the SNARE Vam3 interacts with the HOPS tethering complex to facilitate vacuole fusion
    In: The Journal of Biological Chemistry (JBC), Vol. 290, 2015, Nr. 9, pp. 5405 – 5413
    DOI (Open Access)
  • Patasi, Csilla; Godočíková, Jana; Michlíková, Soňa; Nie, Yan; Káčeriková, Radka; Kválová, Katarína; Raunser, Stefan; Farkašovský, Marian
    The role of Bni5 in the regulation of septin higher-order structure formation
    In: Biological Chemistry, Vol. 396, 2015, Nr. 12, pp. 1325 – 1337
    DOI
  • Erkelenz, Michael; Bauer, Dennis M.; Meyer, Rebecca; Gatsogiannis, Christos; Raunser, Stefan; Sacca, Barbara; Niemeyer, Christof M.
    A facile method for preparation of tailored scaffolds for DNA-origami
    In: Small, Vol. 10, 2014, Nr. 1, pp. 73 – 77
    DOI
  • Rosin, Christopher; Erlkamp, Mirko; Ecken, Julian Von Der; Raunser, Stefan; Winter, Roland
    Exploring the Stability Limits of Actin and Its Suprastructures
    In: Biophysical Journal, Vol. 107, 2014, Nr. 12, pp. 2982 – 2992
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  • Meusch, Dominic; Gatsogiannis, Christos; Efremov, Rouslan G.; Lang, Alexander E.; Hofnagel, Oliver; Vetter, Ingrid R.; Aktories, Klaus; Raunser, Stefan
    Mechanism of Tc toxin action revealed in molecular detail
    In: Nature, Vol. 508, 2014, Nr. 1, pp. 61 – 65
    DOI (Open Access)
  • Petrovic, Arsen; Mosalaganti, Shyamal; Keller, Jenny; Mattiuzzo, Marta; Overlack, Katharina; Krenn, Veronica; De Antoni, Anna; Wohlgemuth, Sabine; Cecatiello, Valentina; Pasqualato, Sebastiano; Raunser, Stefan; Musacchio, Andrea
    Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization
    In: Molecular Cell, Vol. 53, 2014, Nr. 4, pp. 591 – 605
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  • Kapoor, Shobhna; Berghaus, Melanie; Suladze, Saba; Prumbaum, Daniel; Grobelny, Sebastian; Degen, Patrick; Raunser, Stefan; Winter, Roland
    Prebiotic cell membranes that survive extreme environmental pressure conditions
    In: Angewandte Chemie International Edition, Vol. 53, 2014, Nr. 32, pp. 8397 – 8401
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  • Behrmann, Heide; Lürick, Anna; Kuhlee, Anne; Balderhaar, Henning Kleine; Bröcker, Cornelia; Kümmel, Daniel; Engelbrecht-Vandré, Siegfried; Gohlke, Ulrich; Raunser, Stefan; Heinemann, Udo; Ungermann, Christian
    Structural identification of the Vps18 β-propeller reveals a critical role in the HOPS complex stability and function
    In: The Journal of Biological Chemistry (JBC), Vol. 289, 2014, Nr. 48, pp. 33503 – 33512
    DOI (Open Access)
  • Thakur, Harish C.; Singh, Madhurendra; Nagel-Steger, Luitgard; Kremer, Jana; Prumbaum, Daniel; Fansa, Eyad Kalawy; Ezzahoini, Hakima; Nouri, Kazem; Gremer, Lothar; Abts, André; Schmitt, Lutz; Raunser, Stefan; Ahmadian, Mohammad R.; Piekorz, Roland P.
    The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner
    In: The Journal of Biological Chemistry (JBC), Vol. 289, 2014, Nr. 1, pp. 74 – 88
    DOI (Open Access)
  • Basilico, Federica; Maffini, Stefano; Weir, John R.; Prumbaum, Daniel; Rojas, Ana M.; Zimniak, Tomasz; De Antoni, Anna; Jeganathan, Sadasivam; Voss, Beate; Van Gerwen, Suzan; Krenn, Veronica; Massimiliano, Lucia; Valencia, Alfonso; Vetter, Ingrid R.; Herzog, Franz; Raunser, Stefan; Pasqualato, Sebastiano; Musacchio, Andrea
    The pseudo GTPase CENP-M drives human kinetochore assembly
    In: eLife, Vol. 3, 2014, pp. e02978
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  • Gatsogiannis, Christos; Lang, Alexander E.; Meusch, Dominic; Pfaumann, Vanda; Hofnagel, Oliver; Benz, Roland; Aktories, Klaus; Raunser, Stefan
    A syringe-like injection mechanism in Photorhabdus luminescens toxins
    In: Nature, Vol. 495, 2013, Nr. 7442, pp. 520 – 523
    DOI (Open Access)
  • Schönichen, André; Mannherz, Hans Georg; Behrmann, Elmar; Mazur, Antonina J.; Kühn, Sonja; Silván, Unai; Schoenenberger, Cora-Ann; Fackler, Oliver T.; Raunser, Stefan; Dehmelt, Leif; Geyer, Matthias
    FHOD1 is a combined actin filament capping and bundling factor that selectively associates with actin arcs and stress fibers
    In: Journal of Cell Science, Vol. 126, 2013, Nr. 8, pp. 1891 – 1901
    DOI (Open Access)
  • Taft, Manuel H.; Behrmann, Elmar; Munske-Weidemann, Lena-Christin; Thiel, Claudia; Raunser, Stefan; Manstein, Dietmar J.
    Functional Characterization of Human Myosin-18A and Its Interaction with F-actin and GOLPH3
    In: The Journal of Biological Chemistry (JBC), Vol. 288, 2013, Nr. 42, pp. 30029 – 30041
    DOI (Open Access)
  • Lehman, William; Orzechowski, Marek; Li, Xiaochuan Edward; Fischer, Stefan; Raunser, Stefan
    Gestalt-Binding of tropomyosin on actin during thin filament activation
    In: Journal of Muscle Research and Cell Motility, Vol. 34, 2013, Nr. 3-4, pp. 155 – 163
    DOI (Open Access)
  • Lakshminarasimhan, Mahadevan; Curth, Ute; Moniot, Sebastien; Mosalaganti, Shyamal; Raunser, Stefan; Steegborn, Clemens
    Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol
    In: Bioscience Reports, Vol. 33, 2013, Nr. 3
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  • Sot, Begoña; Behrmann, Elmar; Raunser, Stefan; Wittinghofer, Alfred
    Ras GTPase activating (RasGAP) activity of the dual specificity GAP protein Rasal requires colocalization and C2 domain binding to lipid membranes
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 110, 2013, Nr. 1, pp. 111 – 116
    DOI (Open Access)
  • Thakur, Harish C.; Singh, Madhurendra; Nagel-Steger, Luitgard; Prumbaum, Daniel; Fansa, Eyad Kalawy; Gremer, Lothar; Ezzahoini, Hakima; Abts, André; Schmitt, Lutz; Raunser, Stefan; Ahmadian, Mohammad R.; Piekorz, Roland P.
    Role of centrosomal adaptor proteins of the TACC family in the regulation of microtubule dynamics during mitotic cell division
    In: Biological Chemistry, Vol. 394, 2013, Nr. 11, pp. 1411 – 1423
    DOI (Open Access)
  • Sadian, Yashar; Gatsogiannis, Christos; Patasi, Csilla; Hofnagel, Oliver; Goody, Roger S.; Farkašovský, Marian; Raunser, Stefan
    The role of Cdc42 and Gic1 in the regulation of septin filament formation and dissociation
    In: eLife, Vol. 2013, 2013, Nr. 2, e01085
    DOI (Open Access)
  • Müller, Mirco; Mazur, Antonina Joanna; Behrmann, Elmar; Diensthuber, Ralph P.; Radke, Michael B.; Qu, Zheng; Littwitz, Christoph; Raunser, Stefan; Schoenenberger, Cora-Ann; Manstein, Dietmar J.; Mannherz, Hans Georg
    Functional characterization of the human α-cardiac actin mutations Y166C and M305L involved in hypertrophic cardiomyopathy
    In: Cellular and Molecular Life Sciences - CMLS, Vol. 69, 2012, Nr. 20, pp. 3457 – 3479
    DOI (Open Access)
  • Hernandez, Javier M.; Stein, Alexander; Behrmann, Elmar; Riedel, Dietmar; Cypionka, Anna; Farsi, Zohreh; Walla, Peter J.; Raunser, Stefan; Jahn, Reinhard
    Membrane fusion intermediates via directional and full assembly of the SNARE complex
    In: Science, Vol. 336, 2012, Nr. 6088, pp. 1581 – 1584
    DOI (Open Access)
  • Bröcker, Cornelia; Kuhlee, Anne; Gatsogiannis, Christos; kleine Balderhaar, Henning J.; Hönscher, Carina; Engelbrecht-Vandré, Siegfried; Ungermann, Christian; Raunser, Stefan
    Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 109, 2012, Nr. 6, pp. 1991 – 1996
    DOI (Open Access)
  • Behrmann, Elmar; Tao, Guozhi; Stokes, David L.; Egelman, Edward H.; Raunser, Stefan; Penczek, Pawel A.
    Real-space processing of helical filaments in SPARX
    In: Journal of Structural Biology, Vol. 177, 2012, Nr. 2, pp. 302 – 313
    DOI (Open Access)
  • Behrmann, Elmar; Müller, Mirco; Penczek, Pawel A.; Mannherz, Hans Georg; Manstein, Dietmar J.; Raunser, Stefan
    Structure of the rigor actin-tropomyosin-myosin complex
    In: Cell, Vol. 150, 2012, Nr. 2, pp. 327 – 338
    DOI (Open Access)
  • Schneider, Robert; Schumacher, Miria C.; Mueller, Henrik; Nand, Deepak; Klaukien, Volker; Heise, Henrike; Riedel, Dietmar; Wolf, Gerhard; Behrmann, Elmar; Raunser, Stefan; Seidel, Ralf; Engelhard, Martin; Baldus, Marc
    Structural characterization of polyglutamine fibrils by solid-state NMR spectroscopy
    In: Journal of Molecular Biology (JMB), Vol. 412, 2011, Nr. 1, pp. 121 – 136
    DOI (Open Access)
  • Wang, Liwei; Yang, Jin Kuk; Kabaleeswaran, Venkataraman; Rice, Amanda J; Cruz, Anthony C; Park, Ah Young; Yin, Qian; Damko, Ermelinda; Jang, Se Bok; Raunser, Stefan; Robinson, Carol V; Siegel, Richard M; Walz, Thomas; Wu, Hao
    The Fas–FADD death domain complex structure reveals the basis of DISC assembly and disease mutations
    In: Nature Structural & Molecular Biology, Vol. 17, 2010, Nr. 11, pp. 1324 – 1329
    DOI
  • Raunser, Stefan; Walz, Thomas
    Electron Crystallography as a Technique to Study the Structure on Membrane Proteins in a Lipidic Environment
    In: Annual Review of Biophysics, Vol. 38, 2009, Nr. 1, pp. 89 – 105
    DOI (Open Access)
  • Raunser, Stefan; Mathai, John C.; Abeyrathne, Priyanka D.; Rice, Amanda J.; Zeidel, Mark L.; Walz, Thomas
    Oligomeric Structure and Functional Characterization of the Urea Transporter from Actinobacillus pleuropneumoniae
    In: Journal of Molecular Biology (JMB), Vol. 387, 2009, Nr. 3, pp. 619 – 627
    DOI (Open Access)
  • Raunser, Stefan; Magnani, Roberta; Huang, Zhong; Houtz, Robert L.; Trievel, Raymond C.; Penczek, Pawel A.; Walz, Thomas
    Rubisco in complex with Rubisco large subunit methyltransferase
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), Vol. 106, 2009, Nr. 9, pp. 3160 – 3165
    DOI (Open Access)
  • Park, Chan Young; Hoover, Paul J.; Mullins, Franklin M.; Bachhawat, Priti; Covington, Elizabeth D.; Raunser, Stefan; Walz, Thomas; Garcia, K. Christopher; Dolmetsch, Ricardo E.; Lewis, Richard S.
    STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1
    In: Cell, Vol. 136, 2009, Nr. 5, pp. 876 – 890
    DOI (Open Access)
  • Park, Hyun Ho; Logette, Emmanuelle; Raunser, Stefan; Cuenin, Solange; Walz, Thomas; Tschopp, Jurg; Wu, Hao
    Death Domain Assembly Mechanism Revealed by Crystal Structure of the Oligomeric PIDDosome Core Complex
    In: Cell, Vol. 128, 2007, Nr. 3, pp. 533 – 546
    DOI (Open Access)
  • Hite, Richard K.; Raunser, Stefan; Walz, Thomas
    Revival of electron crystallography
    In: Current Opinion in Structural Biology, Vol. 17, 2007, Nr. 4, pp. 389 – 395
    DOI (Open Access)
  • Bankovich, Alexander J.; Raunser, Stefan; Juo, Z. Sean; Walz, Thomas; Davis, Mark M.; Garcia, K. Christopher
    Structural Insight into Pre-B Cell Receptor Function
    In: Science, Vol. 316, 2007, Nr. 5822, pp. 291 – 294
    DOI (Open Access)
  • Yildiz, Özkan; Kalthoff, Christoph; Raunser, Stefan; Kühlbrandt, Werner
    Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptake
    In: The EMBO Journal, Vol. 26, 2007, Nr. 2, pp. 589 – 599
    DOI (Open Access)
  • Mougous, Joseph D.; Cuff, Marianne E.; Raunser, Stefan; Shen, Aimee; Zhou, Min; Gifford, Casey A.; Goodman, Andrew L.; Joachimiak, Grazyna; Ordoñez, Claudia L.; Lory, Stephen; Walz, Thomas; Joachimiak, Andrzej; Mekalanos, John J.
    A Virulence Locus of Pseudomonas aeruginosa Encodes a Protein Secretion Apparatus
    In: Science, Vol. 312, 2006, Nr. 5779, pp. 1526 – 1530
    DOI (Open Access)
  • Hobe, Stephan; Trostmann, Inga; Raunser, Stefan; Paulsen, Harald
    Assembly of the Major Light-harvesting Chlorophyll-a/b Complex
    In: The Journal of Biological Chemistry (JBC), Vol. 281, 2006, Nr. 35, pp. 25156 – 25166
    DOI (Open Access)
  • Raunser, Stefan; Haase, Winfried; Franke, Cornelia; Eckert, Gunter P.; Müller, Walter E.; Kühlbrandt, Werner
    Heterologously expressed GLT-1 associates in ∼200-nm protein-lipid islands
    In: Biophysical Journal, Vol. 91, 2006, Nr. 10, pp. 3718 – 3726
    DOI (Open Access)
  • Vinothkumar, Kutti Ragunath; Raunser, Stefan; Jung, Heinrich; Kühlbrandt, Werner
    Oligomeric Structure of the Carnitine Transporter CaiT from Escherichia coli
    In: The Journal of Biological Chemistry (JBC), Vol. 281, 2006, Nr. 8, pp. 4795 – 4801
    DOI (Open Access)
  • Raunser, Stefan; Appel, Matthias; Ganea, Constanta; Geldmacher-Kaufer, Ulrike; Fendler, Klaus; Kühlbrandt, Werner
    Structure and Function of Prokaryotic Glutamate Transporters from Escherichia coli and Pyrococcus horikoshii
    In: Biochemistry, Vol. 45, 2006, Nr. 42, pp. 12796 – 12805
    DOI
  • Kim, Yeon-Gil; Raunser, Stefan; Munger, Christine; Wagner, John; Song, Young-Lan; Cygler, Miroslaw; Walz, Thomas; Oh, Byung-Ha; Sacher, Michael
    The Architecture of the Multisubunit TRAPP I Complex Suggests a Model for Vesicle Tethering
    In: Cell, Vol. 127, 2006, Nr. 4, pp. 817 – 830
    DOI (Open Access)
  • Raunser, Stefan; Haase, Winfried; Bostina, Mihnea; Parcej, David N.; Kühlbrandt, Werner
    High-yield expression, reconstitution and structure of the recombinant, fully functional glutamate transporter GLT-1 from Rattus norvegicus
    In: Journal of Molecular Biology (JMB), Vol. 351, 2005, Nr. 3, pp. 598 – 613
    DOI (Open Access)
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