ZMB member Katharina Lückerath

ZMB Member
Katharina Lückerath

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Katharina Lückerath portrait
© K.Lückerath

Prof. Dr. Katharina Lückerath

Clinic for Nuclear Medicine
University Hospital Essen
Hufelandstr. 55
45122 Essen

Research Overview

Our group focuses on theranostic approaches with the goal to deliver new insights into tumor biology, heterogeneity and metabolism and their relationship and relevance to functional imaging and biomarker-driven treatments in nuclear medicine.
Theranostics use radioligands that bind to cell surface receptors on target cells. Radioligands labeled with isotopes such as Gallium-68 or Fluor-18 enable imaging of target expression by positron emission tomography (PET). The same or a similar ligand labeled with alpha or beta radiation emitting isotopes delivers therapeutic radiation specifically to target expressing tissues (radionuclide therapy; RNT). In contrast to conventional radiotherapy, RNTs are systemically administered; as a consequence, metastases throughout the body can be targeted, and tumors are irradiated for hours to days.
Radionuclide therapy is a promising treatment option for various cancers. However, outcomes are rarely curative. We address this clinical need by investigating new RNT modalities and the mechanisms underlying the limited effectiveness of RNT. These mechanisms include, for example, tumor cell intrinsic resistance mechanisms, tumor protection by microenvironmental factors, and a suboptimal radiotherapeutic strategy. Poor understanding of these mechanisms represents a key barrier to the development of more effective RNT approaches. To improve radionuclide therapy outcomes and to establish rationally chosen, translatable RNT-based combination therapies, we characterize cancer mouse models and patient samples, and use diverse in vitro, ex vivo, and in vivo analyses to identify targetable RNT-induced alterations in tumor, stroma and immune cells that mitigate the effects of RNT and could be exploited therapeutically.
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Selected Publications

    Journal articles

  • Costa, Pedro Fragoso; Püllen, Lukas; Kesch, Claudia; Krafft, Ulrich; Tschirdewahn, Stephan; Moraitis, Alexandros; Radtke, Jan Philipp; Ting, Saskia; Nader, Michael; Wosniack, Jasmin; Kersting, David; Lückerath, Katharina; Herrmann, Ken; Fendler, Wolfgang; Hadaschik, Boris; Darr, Christopher
    18F-PSMA Cerenkov Luminescence and Flexible Autoradiography Imaging in a Prostate Cancer Mouse Model and First Results of a Radical Prostatectomy Feasibility Study in Men
    In: Journal of Nuclear Medicine (JNM) Vol. 64 (2023) Nr. 4, pp. 598 - 604
  • Handke, Analena; Kesch, Claudia; Fendler, Wolfgang; Telli, Tugce; Liu, Yang; Hakansson, Alexander; Davicioni, Elai; Hughes, Jason; Song, Hong; Lückerath, Katharina; Herrmann, Ken; Hadaschik, Boris; Seifert, Robert
    Analysing the tumor transcriptome of prostate cancer to predict efficacy of Lu-PSMA therapy
    In: Journal for ImmunoTherapy of Cancer Vol. 11 (2023) Nr. 10, e007354
  • Lückerath, Katharina; Trajkovic-Arsic, Marija; Mona, Christine E.
    Fibroblast Activation Protein Inhibitor Theranostics : Preclinical Combination Treatment
    In: PET Clinics Vol. 18 (2023) Nr. 3, pp. 409 - 418
  • Hirmas, Nader; Hamacher, Rainer; Sraieb, Miriam; Ingenwerth, Marc; Kessler, Lukas; Pabst, Kim M.; Barbato, Francesco; Lückerath, Katharina; Kasper, Stefan; Nader, Michael; Schildhaus, Hans-Ulrich; Kesch, Claudia; von Tresckow, Bastian; Hanoun, Christine; Hautzel, Hubertus; Aigner, Clemens; Glas, Martin; Stuschke, Martin; Kümmel, Sherko; Harter, Philipp; Lugnier, Celine; Uhl, Waldemar; Niedergethmann, Marco; Hadaschik, Boris; Grünwald, Viktor; Siveke, Jens; Herrmann, Ken; Fendler, Wolfgang
    Fibroblast-Activation Protein PET and Histopathology in a Single-Center Database of 324 Patients and 21 Tumor Entities
    In: Journal of Nuclear Medicine (JNM) Vol. 64 (2023) Nr. 5, pp. 711 - 716
  • Küper, Alina; Blanc-Durand, Paul; Gafita, Andrei; Kersting, David; Fendler, Wolfgang; Seibold, Constantin; Moraitis, Alexandros; Lückerath, Katharina; James, Michelle L.; Seifert, Robert
    Is There a Role of Artificial Intelligence in Preclinical Imaging?
    In: Seminars in Nuclear Medicine Vol. 53 (2023) Nr. 5, pp. 687 - 693
  • Demmert, Tristan T.; Maric, Ines; Pomykala, Kelsey L.; Lueckerath, Katharina; Siveke, Jens; Schaarschmidt, Benedikt M.; Hamacher, Rainer; Herrmann, Ken; Fendler, Wolfgang P.
    Novel ⁶⁸Ga-FAPI PET/CT Offers Oncologic Staging Without COVID-19 Vaccine-Related Pitfalls
    In: Journal of Nuclear Medicine (JNM) Vol. 64 (2023) Nr. 3, pp. 368 - 371
  • Demmert, Tristan T.; Pomykala, Kelsey L.; Lanzafame, Helena; Pabst, Kim M.; Lueckerath, Katharina; Siveke, Jens; Umutlu, Lale; Hautzel, Hubertus; Hamacher, Rainer; Herrmann, Ken; Fendler, Wolfgang P.
    Oncologic Staging with ⁶⁸Ga-FAPI PET/CT Demonstrates a Lower Rate of Nonspecific Lymph Node Findings Than ¹⁸F-FDG PET/CT
    In: Journal of Nuclear Medicine (JNM) Vol. 64 (2023) Nr. 12, pp. 1906 - 1909
  • Civan, Caner; Kasper, Stefan; Berliner, Christoph; Fragoso-Costa, Pedro; Grünwald, Viktor; Pogorzelski, Michael; Schaarschmidt, Benedikt Michael; Lang, Stephan; Kersting, David; Nader, Michael; Lückerath, Katharina; Herrmann, Ken; Fendler, Wolfgang P.; Weber, Manuel
    PSMA-Directed Imaging and Therapy of Salivary Gland Tumors : A Single-Center Retrospective Study
    In: Journal of Nuclear Medicine (JNM) Vol. 64 (2023) Nr. 3, pp. 372 - 378
  • Storey, Claire M.; Altai, Mohamed; Bicak, Mesude; Veach, Darren R.; Lückerath, Katharina; Adrian, Gabriel; McDevitt, Michael R.; Kalidindi, Teja; Park, Julie E.; Herrmann, Ken; Abou, Diane; Zedan, Wahed; Peekhaus, Norbert; Klein, Robert J.; Damoiseaux, Robert; Larson, Steven M.; Lilja, Hans; Thorek, Daniel; Ulmert, David
    Quantitative In Vivo Imaging of the Androgen Receptor Axis Reveals Degree of Prostate Cancer Radiotherapy Response
    In: Molecular Cancer Research Vol. 21 (2023) Nr. 4, pp. 307 - 315
  • Pabst, Kim M.; Trajkovic-Arsic, Marija; Cheung, Phyllis F Y; Ballke, Simone; Steiger, Katja; Bartel, Timo; Schaarschmidt, Benedikt M.; Milosevic, Aleksandar; Seifert, Robert; Nader, Michael; Kessler, Lukas; Siveke, Jens; Lückerath, Katharina; Kasper, Stefan; Herrmann, Ken; Hirmas, Nader; Schmidt, Hartmut; Hamacher, Rainer; Fendler, Wolfgang
    Superior Tumor Detection for ⁶⁸Ga-FAPI-46 Versus ¹⁸F-FDG PET/CT and Conventional CT in Patients with Cholangiocarcinoma
    In: Journal of Nuclear Medicine (JNM) Vol. 64 (2023) Nr. 7, pp. 1049 - 1055
  • Meyer, Catherine; Stuparu, Andreea; Lückerath, Katharina; Calais, Jeremie; Czernin, Johannes; Slavik, Roger; Dahlbom, Magnus
    Tandem Isotope Therapy with ²²⁵Ac- and ¹⁷⁷Lu-PSMA-617 in a Murine Model of Prostate Cancer
    In: Journal of Nuclear Medicine (JNM) Vol. 64 (2023) Nr. 11, pp. 1772 - 1778
  • Klose, Jasmin M.; Wosniack, Jasmin; Iking, Janette; Staniszewska, Magdalena; Zarrad, Fadi; Trajkovic-Arsic, Marija; Herrmann, Ken; Costa, Pedro Fragoso; Lückerath, Katharina; Fendler, Wolfgang
    Administration Routes for SSTR-/PSMA- and FAP-Directed Theranostic Radioligands in Mice
    In: Journal of Nuclear Medicine (JNM) Vol. 63 (2022) Nr. 9, pp. 1357 - 1363
  • Meyer, Catherine; Prasad, Vikas; Stuparu, Andreea; Kletting, Peter; Glatting, Gerhard; Miksch, Jonathan; Solbach, Christoph; Lückerath, Katharina; Nyiranshuti, Lea; Zhu, Shaojun; Czernin, Johannes; Beer, Ambros J.; Slavik, Roger; Calais, Jeremie; Dahlbom, Magnus
    Comparison of PSMA-TO-1 and PSMA-617 labeled with gallium-68, lutetium-177 and actinium-225
    In: EJNMMI Research Vol. 12 (2022) Nr. 1, 65
  • Kessler, Lukas; Ferdinandus, Justin; Hirmas, Nader; Zarrad, Fadi; Nader, Michael; Kersting, David; Weber, Manuel; Kazek, Sandra; Sraieb, Miriam; Hamacher, Rainer; Lückerath, Katharina; Umutlu, Lale; Fendler, Wolfgang; Rischpler, Christoph
    Pitfalls and Common Findings in ⁶⁸Ga-FAPI PET : A Pictorial Analysis
    In: Journal of Nuclear Medicine (JNM) Vol. 63 (2022) Nr. 6, pp. 890 - 896
  • Ferdinandus, Justin; Fendler, Wolfgang; Lückerath, Katharina; Berliner, Christoph; Kurzidem, Sabine; Hadaschik, Eva; Klode, Joachim; Zimmer, Lisa; Livingstone, Elisabeth; Schadendorf, Dirk; Herrmann, Ken; Becker, Jürgen; Ugurel, Selma
    Response to Combined Peptide Receptor Radionuclide Therapy and Checkpoint Immunotherapy with Ipilimumab Plus Nivolumab in Metastatic Merkel Cell Carcinoma
    In: Journal of Nuclear Medicine (JNM) Vol. 63 (2022) Nr. 3, pp. 396 - 398
  • Fendler, Wolfgang; Pabst, Kim M.; Kessler, Lukas; Fragoso Costa, Pedro; Ferdinandus, Justin; Weber, Manuel; Lippert, Maria; Lückerath, Katharina; Umutlu, Lale; Kostbade, Karina; Mavroeidi, Ilektra A.; Schuler, Martin; Ahrens, Marit; Rischpler, Christoph; Bauer, Sebastian; Herrmann, Ken; Siveke, Jens; Hamacher, Rainer
    Safety and Efficacy of 90Y-FAPI-46 Radioligand Therapy in Patients with Advanced Sarcoma and Other Cancer Entities
    In: Clinical Cancer Research Vol. 28 (2022) Nr. 19, pp. 4346 - 4353
  • Staniszewska, Magdalena; Iking, Janette; Lückerath, Katharina; Hadaschik, Boris; Herrmann, Ken; Ferdinandus, Justin; Fendler, Wolfgang
    Drug and molecular radiotherapy combinations for metastatic castration resistant prostate cancer
    In: Nuclear Medicine and Biology Vol. 96-97 (2021) pp. 101 - 111
  • Staniszewska, Magdalena; Fragoso Costa, Pedro; Eiber, Matthias; Klose, Jasmin M.; Wosniack, Jasmin; Reis, Henning; Szarvas, Tibor; Hadaschik, Boris; Lückerath, Katharina; Herrmann, Ken; Fendler, Wolfgang; Iking, Janette
    Enzalutamide enhances psma expression of psma-low prostate cancer
    In: International Journal of Molecular Sciences (IJMS) Vol. 22 (2021) Nr. 14, 7431
  • Iking, Janette; Staniszewska, Magdalena; Kessler, Lukas; Klose, Jasmin M.; Lückerath, Katharina; Fendler, Wolfgang; Herrmann, Ken; Rischpler, Christoph
    Imaging Inflammation with Positron Emission Tomography
    In: Biomedicines Vol. 9 (2021) Nr. 2, pp. 212
  • Czernin, Johannes; Current, Kyle; Mona, Christine E.; Nyiranshuti, Lea; Hikmat, Firas; Radu, Caius G.; Lückerath, Katharina
    Immune-Checkpoint Blockade Enhances ²²⁵Ac-PSMA617 Efficacy in a Mouse Model of Prostate Cancer
    In: Journal of Nuclear Medicine (JNM) Vol. 62 (2021) Nr. 2, pp. 228 - 231
  • Stuparu, Andreea D.; Capri, Joseph R.; Meyer, Catherine; Le, Thuc M.; Evans-Axelsson, Susan L.; Current, Kyle; Lennox, Mark; Mona, Christine E.; Fendler, Wolfgang; Calais, Jérémie; Eiber, Matthias; Dahlbom, Magnus; Czernin, Johannes; Radu, Caius G.; Lückerath, Katharina; Slavik, Roger
    Mechanisms of Resistance to Prostate-Specific Membrane Antigen-Targeted Radioligand Therapy in a Mouse Model of Prostate Cancer
    In: Journal of Nuclear Medicine (JNM) Vol. 62 (2021) Nr. 7, pp. 989 - 995
  • Veach, Darren R.; Storey, Claire M.; Lückerath, Katharina; Braun, Katharina; von Bodman, Christian; Lamminmäki, Urpo; Kalidindi, Teja; Strand, Sven-Erik; Strand, Joanna; Altai, Mohamed; Damoiseaux, Robert; Zanzonico, Pat; Benabdallah, Nadia; Pankov, Dmitry; Scher, Howard I.; Scardino, Peter; Larson, Steven M.; Lilja, Hans; McDevitt, Michael R.; Thorek, Daniel L.J.; Ulmert, David
    PSA-Targeted Alpha-, Beta-, and Positron-Emitting Immunotheranostics in Murine Prostate Cancer Models and Nonhuman Primates
    In: Clinical Cancer Research Vol. 27 (2021) Nr. 7, pp. 2050 - 2060
  • Bicak, Mesude; Lückerath, Katharina; Kalidindi, Teja; Phelps, Michael E.; Strand, Sven-Erik; Morris, Michael J.; Radu, Caius G.; Damoiseaux, Robert; Peltola, Mari T.; Peekhaus, Norbert; Ho, Austin; Veach, Darren; Malmborg Hager, Ann-Christin; Larson, Steven M.; Lilja, Hans; McDevitt, Michael R.; Klein, Robert J.; Ulmert, David
    Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Vol. 117 (2020) Nr. 26, pp. 15172 - 15181
  • Current, Kyle; Meyer, Catherine; Magyar, Clara E.; Mona, Christine E.; Almajano, Joel; Slavik, Roger; Stuparu, Andreea D.; Cheng, Chloe; Dawson, David W.; Radu, Caius G.; Czernin, Johannes; Lückerath, Katharina
    Investigating PSMA-Targeted Radioligand Therapy Efficacy as a Function of Cellular PSMA Levels and Intratumoral PSMA Heterogeneity
    In: Clinical Cancer Research Vol. 26 (2020) Nr. 12, pp. 2946 - 2955
  • Stuparu, Andreea D.; Meyer, Catherine A.L.; Evans-Axelsson, Susan L.; Lückerath, Katharina; Wei, Liu H.; Kim, Woosuk; Poddar, Soumya; Mona, Christine E.; Dahlbom, Magnus; Girgis, Mark D.; Radu, Caius G.; Czernin, Johannes; Slavik, Roger
    Targeted alpha therapy in a systemic mouse model of prostate cancer : A feasibility study
    In: Theranostics Vol. 10 (2020) Nr. 6, pp. 2612 - 2620
  • Lapa, Constantin; Lückerath, Katharina; Kircher, Stefan; Hänscheid, Heribert; Grigoleit, Götz U.; Rosenwald, Andreas; Stolzenburg, Antje; Kropf, Saskia; Einsele, Hermann; Wester, Hans-Jürgen; Buck, Andreas K.; Kortüm, Klaus M.; Schirbel, Andreas
    Potential influence of concomitant chemotherapy on CXCR4 expression in receptor directed endoradiotherapy
    In: British Journal of Haematology Vol. 184 (2019) Nr. 3, pp. 440 - 443
  • Lückerath, Katharina; Stuparu, Andreea D.; Wei, Liu; Kim, Woosuk; Radu, Caius G.; Mona, Christine E.; Calais, Jeremie; Rettig, Matthew; Reiter, Robert E.; Czernin, Johannes; Slavik, Roger; Herrmann, Ken; Eiber, Matthias; Fendler, Wolfgang P.
    Detection Threshold and Reproducibility of ⁶⁸Ga-PSMA11 PET/CT in a Mouse Model of Prostate Cancer
    In: Journal of Nuclear Medicine (JNM) Vol. 59 (2018) Nr. 9, pp. 1392 - 1397
  • Lückerath, Katharina; Wei, Liu; Fendler, Wolfgang; Evans-Axelsson, Susan; Stuparu, Andreea D.; Slavik, Roger; Mona, Christine E.; Calais, Jeremie; Rettig, Matthew; Reiter, Robert E.; Herrmann, Ken; Radu, Caius G.; Czernin, Johannes; Eiber, Matthias
    Preclinical evaluation of PSMA expression in response to androgen receptor blockade for theranostics in prostate cancer
    In: EJNMMI Research Vol. 8 (2018) Nr. 1, 96
  • Lapa, Constantin; Herrmann, Ken; Schirbel, Andreas; Hänscheid, Heribert; Lückerath, Katharina; Schottelius, Margret; Kircher, Malte; Werner, Rudolf A.; Schreder, Martin; Samnick, Samuel; Kropf, Saskia; Knop, Stefan; Buck, Andreas K.; Einsele, Hermann; Wester, Hans-Juergen; Kortüm, K. Martin
    CXCR4-directed endoradiotherapy induces high response rates in extramedullary relapsed Multiple Myeloma
    In: Theranostics Vol. 7 (2017) Nr. 6, pp. 1589 - 1597
  • Fendler, Wolfgang; Stuparu, Andreea D.; Evans-Axelsson, Susan; Lückerath, Katharina; Wei, Liu; Kim, Woosuk; Poddar, Soumya; Said, Jonathan; Radu, Caius G.; Eiber, Matthias; Czernin, Johannes; Slavik, Roger; Herrmann, Ken
    Establishing 177Lu-PSMA-617 Radioligand Therapy in a Syngeneic Model of Murine Prostate Cancer
    In: Journal of Nuclear Medicine (JNM) Vol. 58 (2017) Nr. 11, pp. 1786 - 1792
  • Lapa, Constantin; Kircher, Stefan; Schirbel, Andreas; Rosenwald, Andreas; Kropf, Saskia; Pelzer, Theo; Walles, Thorsten; Buck, Andreas K.; Weber, Wolfgang A.; Wester, Hans-Juergen; Herrmann, Ken; Lückerath, Katharina
    Targeting CXCR4 with [68Ga]Pentixafor : A suitable theranostic approach in pleural mesothelioma?
    In: OncoTarget Vol. 8 (2017) Nr. 57, pp. 96732 - 96737
  • Lapa, Constantin; Schreder, Martin; Schirbel, Andreas; Samnick, Samuel; Kortüm, Klaus Martin; Herrmann, Ken; Kropf, Saskia; Einsele, Herrmann; Buck, Andreas K; Wester, Hans-Jürgen; Knop, Stefan; Lückerath, Katharina
    [68Ga]Pentixafor-PET/CT for imaging of chemokine receptor CXCR4 expression in multiple myeloma - Comparison to [18F]FDG and laboratory values
    In: Theranostics Vol. 7 (2017) Nr. 1, pp. 205 - 212
  • Lapa, Constantin; Garcia-Velloso, Maria J; Lückerath, Katharina; Samnick, Samuel; Schreder, Martin; Otero, Paula Rodriguez; Schmid, Jan-Stefan; Herrmann, Ken; Knop, Stefan; Buck, Andreas K; Einsele, Hermann; San-Miguel, Jesus; Kortüm, Klaus Martin
    ¹¹C-Methionine-PET in Multiple Myeloma : A Combined Study from Two Different Institutions
    In: Theranostics Vol. 7 (2017) Nr. 11, pp. 2956 - 2964
  • Herrmann, Ken; Schottelius, Margret; Lapa, Constantin; Osl, Theresa; Poschenrieder, Andreas; Hänscheid, Heribert; Lückerath, Katharina; Schreder, Martin; Bluemel, Christina; Knott, Markus; Keller, Ulrich; Schirbel, Andreas; Samnick, Samuel; Lassmann, Michael; Kropf, Saskia; Buck, Andreas K.; Einsele, Hermann; Wester, Hans-Juergen; Knop, Stefan
    First-in-human experience of CXCR4-directed endoradiotherapy with ¹⁷⁷Lu-and ⁹⁰Y-labeled pentixather in advanced-stage multiple myeloma with extensive intra-and extramedullary disease
    In: Journal of Nuclear Medicine (JNM) Vol. 57 (2016) Nr. 2, pp. 248 - 251
  • Lapa, Constantin; Knop, Stefan; Schreder, Martin; Rudelius, Martina; Knott, Markus; Jörg, Gerhard; Samnick, Samuel; Herrmann, Ken; Buck, Andreas K.; Einsele, Hermann; Lückerath, Katharina
    ¹¹C-methionine-PET in multiple myeloma : Correlation with clinical parameters and bone marrow involvement
    In: Theranostics Vol. 6 (2016) Nr. 2, pp. 254 - 261
  • Philipp-Abbrederis, Kathrin; Herrmann, Ken; Knop, Stefan; Schottelius, Margret; Eiber, Matthias; Lückerath, Katharina; Pietschmann, Elke; Habringer, Stefan; Gerngroß, Carlos; Franke, Katharina; Rudelius, Martina; Schirbel, Andreas; Lapa, Constantin; Schwamborn, Kristina; Steidle, Sabine; Hartmann, Elena; Rosenwald, Andreas; Kropf, Saskia; Beer, Ambros J.; Peschel, Christian; Einsele, Hermann; Buck, Andreas K.; Schwaiger, Markus; Götze, Katharina; Wester, Hans-Jürgen; Keller, Ulrich
    In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma
    In: EMBO Molecular Medicine Vol. 7 (2015) Nr. 4, pp. 477 - 487
  • Lückerath, Katharina; Lapa, Constantin; Albert, Christa; Herrmann, Ken; Jörg, Gerhard; Samnick, Samuel; Einsele, Herrmann; Knop, Stefan; Buck, Andreas K.
    ¹¹C-Methionine-PET : A novel and sensitive tool for monitoring of early response to treatment in multiple myeloma
    In: OncoTarget Vol. 6 (2015) Nr. 10, pp. 8418 - 8429
  • Lapa, Constantin; Lückerath, Katharina; Malzahn, Uwe; Samnick, Samuel; Einsele, Herrmann; Buck, Andreas K.; Herrmann, Ken; Knop, Stefan
    ¹⁸FDG-PET/CT for prognostic stratification of patients with multiple myeloma relapse after stem cell transplantation
    In: OncoTarget Vol. 5 (2014) Nr. 17, pp. 7381 - 7391
  • Lückerath, Katharina; Lapa, Constantin; Spahmann, Annika; Jörg, Gerhard; Samnick, Samuel; Rosenwald, Andreas; Einsele, Herrmann; Knop, Stefan; Buck, Andreas K.
    Targeting paraprotein biosynthesis for non-invasive characterization of myeloma biology
    In: PLoS ONE Vol. 8 (2013) Nr. 12, pp. e84840
  • Lückerath, Katharina; Kirkin, Vladimir; Melzer, Inga Maria; Thalheimer, Frederic B.; Siele, Dagmar; Milani, Wiebke; Adler, Thure; Aguilar-Pimentel, Antonio; Horsch, Marion; Michel, Geert; Beckers, Johannes; Busch, Dirk H.; Ollert, Markus; Gailus-Durner, Valerie; Fuchs, Helmut; De Angelis, Martin Hrabě; Staal, Frank J. T.; Rajalingam, Krishnaraj; Hueber, Anne-Odile; Strobl, Lothar J.; Zimber-Strobl, Ursula; Zörnig, Martin
    Immune modulation by Fas ligand reverse signaling : Lymphocyte proliferation is attenuated by the intracellular Fas ligand domain
    In: Blood Vol. 117 (2011) Nr. 2, pp. 519 - 529
  • Kirkin, Vladimir; Cahuzac, Nathalie; Guardiola-Serrano, Francisca; Huault, Sébastien; Lückerath, Katharina; Friedmann, Elena Imre; Novac, Natalia; Wels, Winfried S.; Martoglio, Bruno; Hueber, Anne Odile; Zörnig, Martin
    The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells
    In: Cell Death and Differentiation Vol. 14 (2007) Nr. 9, pp. 1678 - 1687