ZMB Member Thomas Schrader
ZMB Member
Thomas Schrader
Next ZMB-Member
Prof. Dr. Thomas Schrader
Organic Chemistry
Faculty of Chemistry
University of Duisburg-Essen
Universitätsstr. 2
45141 Essen
- +49 201 183 3081
- Website
- Selected Publications
- Publication Metrics
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- ZMB Research Program
Molecular and Chemical Cell Biology
Research Overview
- Molecular tweezers and clamps for enzyme inhibition
- Forceps and clamps against pathological protein aggregation
- β-sheet breakers based on trimeric aminopyrazoles
- Custom-made polymers for the detection of protein surfaces
- Artificial signal transduction with messenger substances
Selected Publications
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Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications Vol. 12 (2021) Nr. 1, pp. 1505
ISSN: 2041-1723Online Full Text: dx.doi.org/ (Open Access) -
CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s diseaseIn: Nature Communications Vol. 11 (2020) Nr. 1, pp. 4885
ISSN: 2041-1723Online Full Text: dx.doi.org/ (Open Access) -
Cell entry of a host-targeting protein of oomycetes requires gp96In: Nature Communications Vol. 9 (2018) Nr. 1, pp. 2347
ISSN: 2041-1723Online Full Text: dx.doi.org/ (Open Access) -
A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14-3-3In: Angewandte Chemie International Edition Vol. 56 (2017) Nr. 31, pp. 8998 - 9002
ISSN: 1521-3773; 1433-7851Online Full Text: dx.doi.org/ (Open Access) -
An NMR Method To Pinpoint Supramolecular Ligand Binding to Basic Residues on ProteinsIn: Angewandte Chemie International Edition Vol. 56 (2017) Nr. 46, pp. 14758 - 14762
ISSN: 1521-3773; 1433-7851Online Full Text: dx.doi.org/ -
Molecular tweezers modulate 14-3-3 protein–protein interactionsIn: Nature Chemistry Vol. 5 (2013) Nr. 3, pp. 234 - 239
ISSN: 1755-4349; 1755-4330Online Full Text: dx.doi.org/ -
Interactions of calix[n]arenes with nucleic acidsIn: Nature Communications Vol. 7 (2012) Nr. 3, pp. 409 - 417
ISSN: 2041-1723 -
Protein recognition : Calixarene connectionIn: Nature Chemistry Vol. 4 (2012) Nr. 7, pp. 519 - 520
ISSN: 1755-4349; 1755-4330Online Full Text: dx.doi.org/ -
Combining independent drug classes into superior, synergistically acting hybrid moleculesIn: Angewandte Chemie International Edition Vol. 49 (2010) Nr. 46, pp. 8743 - 8746
ISSN: 1521-3773; 1433-7851; 0570-0833Online Full Text: dx.doi.org/