ZMB Member Thomas Schrader
ZMB Member
Thomas Schrader
Next ZMB-Member
Prof. Dr. Thomas Schrader
Organic Chemistry
Faculty of Chemistry
University of Duisburg-Essen
Universitätsstr. 2
45141 Essen
- +49 201 183 3081
- Website
- Selected Publications
- Publication Metrics
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- ZMB Research Program
Molecular and Chemical Cell Biology
Research Overview
- Molecular tweezers and clamps for enzyme inhibition
- Forceps and clamps against pathological protein aggregation
- β-sheet breakers based on trimeric aminopyrazoles
- Custom-made polymers for the detection of protein surfaces
- Artificial signal transduction with messenger substances
Selected Publications
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Günter Wulff (1935 –2023) : Father of Molecular ImprintingIn: Angewandte Chemie International Edition , Vol. 63 2024, Nr. 12, e202402244DOI (Open Access)
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Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications , Vol. 12 2021, Nr. 1, pp. 1505DOI, Online Full Text (Open Access)
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CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s diseaseIn: Nature Communications , Vol. 11 2020, Nr. 1, pp. 4885DOI (Open Access)
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Cell entry of a host-targeting protein of oomycetes requires gp96In: Nature Communications , Vol. 9 2018, Nr. 1, pp. 2347DOI (Open Access)
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A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14-3-3In: Angewandte Chemie International Edition , Vol. 56 2017, Nr. 31, pp. 8998 – 9002DOI (Open Access)
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An NMR Method To Pinpoint Supramolecular Ligand Binding to Basic Residues on ProteinsIn: Angewandte Chemie International Edition , Vol. 56 2017, Nr. 46, pp. 14758 – 14762
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Molecular tweezers modulate 14-3-3 protein–protein interactionsIn: Nature Chemistry , Vol. 5 2013, Nr. 3, pp. 234 – 239
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Interactions of calix[n]arenes with nucleic acidsIn: Nature Communications , Vol. 7 2012, Nr. 3, pp. 409 – 417
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Protein recognition : Calixarene connectionIn: Nature Chemistry , Vol. 4 2012, Nr. 7, pp. 519 – 520
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Combining independent drug classes into superior, synergistically acting hybrid moleculesIn: Angewandte Chemie International Edition , Vol. 49 2010, Nr. 46, pp. 8743 – 8746