ZMB Member Tienush Rassaf

ZMB Member
Tienush Rassaf

Next ZMB-Member
Tienush Rassaf portrait
© UKE/T.Rassaf

Prof. Dr. Tienush Rassaf

Director of:

Clinic for Cardiology and Vascular Medicine

University Hospital Essen
Hufelandstraße 55
45147 Essen

Research Overview

  • Myocardial ischemia-reperfusion syndrome
  • Ischemic pre- and postconditioning
  • Hypoxic vasodilation
  • NO-metabolism
  • Hypoxic nitrite signaling
  • Cardio-oncology

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Selected Publications

    Journal articles

  • Mrotzek, Simone M.; Lena, Alessia; Hadzibegovic, Sara; Ludwig, Ria; Al-Rashid, Fadi; Mahabadi, Amir Abbas; Mincu, Raluca I.; Michel, Lars; Johannsen, Laura; Hinrichs, Lena; Schuler, Martin; Keller, Ulrich; Anker, Stefan D.; Landmesser, Ulf; Rassaf, Tienush; Anker, Markus S.; Totzeck, Matthias
    Assessment of coronary artery disease during hospitalization for cancer treatment
    In: Clinical Research in Cardiology Vol. 110 (2021) pp. 200 - 210
    ISSN: 1861-0692; 1861-0684
    Online Full Text: dx.doi.org/ (Open Access)
  • Dykun, Iryna; Mahabadi, Amir Abbas; Rassaf, Tienush
    A clinical perspective on the 2019 ESC/EAS guidelines for the management of dyslipidaemias: PCSK-9 inhibitors for all?
    In: European Heart Journal Vol. 41 (2020) Nr. 24, pp. 2331
    ISSN: 1522-9645
    Online Full Text: dx.doi.org/
  • Balcer, B; Dykun, Iryna; Hendricks, Stefanie; Al-Rashid, Fadi; Totzeck, Matthias; Rassaf, Tienush; Mahabadi, Amir Abbas;
    Anemia increases long-term mortality in patients undergoing conventional coronary angiography – the ECAT registry
    ESC Congress 2020 – The Digital Experience 29 August – 1 September 2020,
    In: European Heart Journal Vol. 41 (2020) Nr. Supplement_2, pp. 1508
    ISSN: 0195-668X; 1522-9645
    Online Full Text: dx.doi.org/
  • Totzeck, Matthias; Siebermair, Johannes; Rassaf, Tienush; Rischpler, Christoph
    Cardiac fibroblast activation detected by positron emission tomography/computed tomography as a possible sign of cardiotoxicity
    In: European Heart Journal Vol. 41 (2020) Nr. 9, pp. 1060
    ISSN: 1522-9645; 0195-668X
    Online Full Text: dx.doi.org/
  • Mauri, Victor; Besler, Christian; Riebisch, Matthias; Al-Hammadi, Osamah; Ruf, Tobias; Gerçek, Muhammed; Horn, Patrick; Grothusen, Christina; Mehr, Michael; Becher, Marc Ulrich; Mues, Christoph; Boeder, Niklas; Kreidel, Felix; Friedrichs, Kai; Westenfeld, Ralf; Braun, Daniel; Öztürk, Can; Baldus, Stephan; Rassaf, Tienush; Thiele, Holger; Nickenig, Georg; Hausleiter, Jörg; Möllmann, Helge; Kelm, Malte; Rudolph, Volker; von Bardeleben, Ralph-Stephan; Nef, Holger M.; Lüdike, Peter; Lurz, Philipp; Pfister, Roman
    German Multicenter Experience With a New Leaflet-Based Transcatheter Mitral Valve Repair System for Mitral Regurgitation
    In: JACC Cardiovascular Interventions Vol. 13 (2020) Nr. 23, pp. 2769 - 2778
    ISSN: 1876-7605; 1936-8798
    Online Full Text: dx.doi.org/
  • Lind, Alexander; Totzeck, Matthias; Mahabadi, Amir Abbas; Janosi, Rolf Alexander; El Gabry, Mohamed; Ruhparwar, Arjang; Mrotzek, Simone; Hinrichs, Lena; Akdeniz, Merve; Rassaf, Tienush; Mincu, Raluca I.
    Impact of Cancer in Patients Undergoing Transcatheter Aortic Valve Replacement: A Single-Center Study
    In: JACC: CardioOncology Vol. 2 (2020) Nr. 5, pp. 735 - 743
    ISSN: 2666-0873
    Online Full Text: dx.doi.org/ (Open Access)
  • Mincu, R.I; Pohl, Julia; Mrotzek, Simone; Michel, Lars; Hinrichs, Lena; Lampe, L; Rassaf, Tienush; Totzeck, Matthias;
    Left ventricular global longitudinal strain reduction in patients with melanoma and extra-cardiac immune-related adverse events during immune checkpoint inhibitor therapy
    ESC Congress 2020 – The Digital Experience 29 August – 1 September 2020,
    In: European Heart Journal Vol. 41 (2020) Nr. Supplement_2, pp. 3261
    ISSN: 0195-668X; 1522-9645
    Online Full Text: dx.doi.org/
  • Rassaf, Tienush; Totzeck, Matthias; Backs, Johannes; Bokemeyer, Carsten; Hallek, Michael; Hilfiker-Kleiner, Denise; Hochhaus, Andreas; Lüftner, Diana; Müller, Oliver J.; Neudorf, Ulrich; Pfister, Roman; von Haehling, Stephan; Lehmann, Lorenz H.; Bauersachs, Johann
    Onco-Cardiology : Consensus Paper of the German Cardiac Society, the German Society for Pediatric Cardiology and Congenital Heart Defects and the German Society for Hematology and Medical Oncology
    In: Clinical Research in Cardiology (2020)
    ISSN: 1861-0692; 1861-0684
    Online Full Text: dx.doi.org/ (Open Access)
  • Mahabadi, Amir Abbas; Rassaf, Tienush
    Radiomic Assessment of Pericoronary Adipose Tissue : Detecting the Vulnerable Patient
    In: Journal of the American College of Cardiology: Cardiovascular Imaging Vol. 13 (2020) Nr. 11, pp. 2384 - 2385
    ISSN: 1876-7591; 1936-878X
    Online Full Text: dx.doi.org/
  • Leppert, Florian; Siebermair, Johannes; Wesemann, Ulrich; Martens, Eimo; Sattler, Stefan M.; Scholz, Stefan; Veith, Stefan; Greiner, Wolfgang; Rassaf, Tienush; Kääb, Stefan; Wakili, Reza
    The INFluence of Remote monitoring on Anxiety/depRession, quality of lifE, and Device acceptance in ICD patients : A prospective, randomized, controlled, single-center trial
    In: Clinical Research in Cardiology (2020) in press
    ISSN: 1861-0692; 1861-0684; 1435-1285; 0300-5860
    Online Full Text: dx.doi.org/ (Open Access)
  • Mincu, Raluca I.; Mahabadi, Amir Abbas; Michel, Lars; Mrotzek, Simone; Schadendorf, Dirk; Rassaf, Tienush; Totzeck, Matthias
    Cardiovascular Adverse Events Associated with BRAF and MEK Inhibitors : A Systematic Review and Meta-analysis
    In: JAMA Network Open Vol. 2 (2019) Nr. 8, pp. e198890
    ISSN: 2574-3805
    Online Full Text: dx.doi.org/ (Open Access)
  • Merz, Simon F.; Korste, Sebastian; Bornemann, Lea; Michel, Lars; Stock, Pia; Squire, Anthony; Soun, Camille; Engel, Daniel Robert; Detzer, Julia; Lörchner, Holger; Hermann, Dirk M.; Kamler, Markus; Klode, Joachim; Hendgen-Cotta, Ulrike B.; Rassaf, Tienush; Gunzer, Matthias; Totzeck, Matthias
    Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response
    In: Nature Communications Vol. 10 (2019) Nr. 1, pp. 2312
    ISSN: 2041-1723
    Online Full Text: dx.doi.org/ (Open Access)
  • Merz, Simon F.; Korste, Sebastian; Bornemann, Lea; Michel, Lars; Stock, Pia; Squire, Anthony; Soun, Camille; Engel, Daniel Robert; Detzer, Julia; Lörchner, Holger; Hermann, Dirk M.; Kamler, Markus; Klode, Joachim; Hendgen-Cotta, Ulrike B.; Rassaf, Tienush; Gunzer, Matthias; Totzeck, Matthias
    Publisher Correction: Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response
    In: Nature Communications Vol. 10 (2019) Nr. 1, pp. 2768
    ISSN: 2041-1723
    Online Full Text: dx.doi.org/ (Open Access)
  • Totzeck, Matthias; Mahabadi, Amir Abbas; Schlosser, Thomas Wilfried; Rassaf, Tienush
    Weightlifting unmasks high-risk coronary anomaly
    In: European Heart Journal Vol. 40 (2019) Nr. 1, pp. 72
    ISSN: 0195-668X; 1522-9645
    Online Full Text: dx.doi.org/
  • Mahabadi, Amir Abbas; Rassaf, Tienush
    Imaging of coronary inflammation for cardiovascular risk prediction
    In: The Lancet Vol. 392 (2018) Nr. 10151, pp. 894 - 896
    ISSN: 1474-547X; 0140-6736
    Online Full Text: dx.doi.org/ (Open Access)
  • Lortz, Julia; Tsagakis, Konstantinos; Rammos, Christos; Rogmann, Kim; Horacek, Michael; Schlosser, Thomas Wilfried; Jakob, Heinz G.; Rassaf, Tienush; Janosi, RolfAlexan
    Intravascular ultrasound for stent graft sizing in emergency thoracic endovascular aortic repair
    In: Journal of the American College of Cardiology Vol. 70 (2017) Nr. 18, pp. B297
    ISSN: 0735-1097; 1558-3597
  • Rammos, Christos; Hendgen-Cotta, Ulrike B.; Totzeck, Matthias; Pohl, Julia; Lüdike, Peter; Flögel, Ulrich; Deenen, René; Köhrer, Karl; French, Brent A.; Gödecke, Axel; Kelm, Malte; Rassaf, Tienush
    Impact of dietary nitrate on age-related diastolic dysfunction
    In: European Journal of Heart Failure Vol. 18 (2016) Nr. 6, pp. 599 - 610
    ISSN: 1878-1314; 1388-9842
    Online Full Text: dx.doi.org/ (Open Access)
  • Westhofen, G.; Ganster, C.; Beier, F.; Rassaf, Tienush; Al-Ali, H. K.; Stuhlmann, R.; Glass, B.; Bacher, U.; Brummendorf, T. H.; Germing, U.; Gattermann, N.; Haase, D.
    Iron Overload- accosiated genetic instability in Myelodysplastic Syndrome
    In: Haematologica Vol. 101 (2016) Nr. Suppl. 1, pp. 496 - 496
    ISSN: 0390-6078; 1592-8721
    (Open Access)
  • Heusch, Gerd; Rassaf, Tienush
    Time to Give Up on Cardioprotection? : A Critical Appraisal of Clinical Studies on Ischemic Pre-, Post-, and Remote Conditioning
    In: Circulation Research Vol. 119 (2016) Nr. 5, pp. 676 - 695
    ISSN: 1524-4571; 0009-7330
    Online Full Text: dx.doi.org/
  • Rassaf, Tienush; Totzeck, Matthias; Hendgen-Cotta, Ulrike B.; Shiva, Sruti; Heusch, Gerd; Kelm, Malte
    Circulating nitrite contributes to cardioprotection by remote ischemic preconditioning
    In: Circulation Research Vol. 114 (2014) Nr. 10, pp. 1601 - 1610
    ISSN: 1524-4571; 0009-7330
    Online Full Text: dx.doi.org/
  • Kehmeier, Eva S.; Lepper, Wolfgang; Kropp, Martina; Heiss, Christian; Hendgen-Cotta, Ulrike B.; Balzer, Jan; Neizel, Mirja; Meyer, Christian; Merx, Marc W.; Verde, Pablo E.; Ohmann, Christian; Heusch, Gerd; Kelm, Malte; Rassaf, Tienush
    TNF-α, myocardial perfusion and function in patients with ST-segment elevation myocardial infarction and primary percutaneous coronary intervention
    In: Clinical Research in Cardiology Vol. 101 (2012) Nr. 10, pp. 815 - 827
    ISSN: 1861-0684; 1861-0692
    Online Full Text: dx.doi.org/
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