Fakultät für Biologie
Personenverzeichnis
Die Links zu den Personen führen zum zentralen Personenverzeichnis der UDE, das die Daten aus dem LSF ausliest. Persönliche Informationen können im LSF (nach Login mit der Uni-Kennung) selbst bearbeitet werden.
Fakultät Biologie - Molekularbiologie II
Anschrift
Universitätsstraße 5
45141 Essen
45141 Essen
Raum
S05 R04 H94
Telefon
Telefax
E-Mail
Funktionen
-
Professor/in, Molekularbiologie II
Aktuelle Veranstaltungen
-
2024 SS
- Zell- und Molekularbiologie
- Methods in Cancer Research
- (Einführung in die) Molekularbiologie
- (Einführung in die) Molekularbiologie (LA Ba und Bio B.Sc.); Einführung in die molekulare Zellbiologie (MolBio Bachelor)
- Übung Molekulare Zellbiologie für Molekularbiologen
- Praktikum Chemie für Lehramtsstudierende
- Nano-Biophotonik (optional)
- ZJA40154 WP Molekulare Onkologie
- Anleitung zum wissenschaftlichen Arbeiten
- Molekularbiologie: Übungen zum Verständnis der Fachliteratur
Vergangene Veranstaltungen (max. 10)
-
2023 WS
- Allgemeine Methoden (Bachelor Bio)
- Molecular Cell Biology
- Molekulare Zellbiologie
- Allgemeine Methoden Praktikum (Bachelor Bio); Priorität für G1 oder G2
- Zell- und Molekularbiologie
- Lehramtspraktikum (LA Ma)
- Grundlagen der Biotechnologie (LA Ba); Platzvergabe: 3 Präferenzen angeben
- Molekulare Onkologie
- Anleitung zum wissenschaftlichen Arbeiten
- Allgemeine Methoden in der Molekularbiologie
Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.
-
A Fluorophore-Labeled Lysine Dendrimer with an Oxo-Anion-Binding Motif for Tracking Gene TransfectionIn: ChemBioChem Jg. 24 (2023) Nr. 15, e202300296Online Volltext: dx.doi.org/ (Open Access)
-
Cationic Solution and Solid‐state Emitters : Robust Imaging Agents for Cells, Bacteria and ProtistsIn: Chemistry - A European Journal Jg. 29 (2023) Nr. 38, e202300334Online Volltext: dx.doi.org/ (Open Access)
-
Deoxyestrone-based lipofection agents with solution- and solid-state emission propertiesIn: Organic and Biomolecular Chemistry Jg. 21 (2023) S. 5762 - 5767Online Volltext: dx.doi.org/ (Open Access)
-
Exploiting Vitamin D Receptor and Its Ligands to Target Squamous Cell Carcinomas of the Head and NeckIn: International Journal of Molecular Sciences (IJMS) Jg. 24 (2023) Nr. 5, 4675Online Volltext: dx.doi.org/ (Open Access)
-
Impact of Peptide Sequences on Their Structure and Function : Mimicking of Virus-Like Nanoparticles for Nucleic Acid DeliveryIn: ChemBioChem Jg. 24 (2023) Nr. 1, e202200519Online Volltext: dx.doi.org/ (Open Access)
-
Potentiating Tweezer Affinity to a Protein Interface with Sequence-Defined Macromolecules on NanoparticlesIn: Biomacromolecules Jg. 24 (2023) Nr. 8, S. 3666 - 3679Online Volltext: dx.doi.org/
-
Taspase1 facilitates Topoisomerase IIβ-mediated DNA double-strand breaks driving estrogen-induced transcriptionIn: Cells Jg. 2023 (2023) Nr. 12, 363Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
The Apoptosis Inhibitor Protein Survivin Is a Critical Cytoprotective Resistor against Silica-Based NanotoxicityIn: Nanomaterials Jg. 13 (2023) Nr. 18, 2546Online Volltext: dx.doi.org/ (Open Access)
-
Tuning Nanobodies’ Bioactivity : Coupling to Ultrasmall Gold Nanoparticles Allows the Intracellular Interference with SurvivinIn: Small Jg. 19 (2023) Nr. 33, 2300871 10.1002/smll.202300871Online Volltext: dx.doi.org/ (Open Access)
-
A Bivalent Supramolecular GCP Ligand Enables Blocking of the Taspase1/Importin α InteractionIn: ChemMedChem Jg. 17 (2022) Nr. 1, e202100640Online Volltext: dx.doi.org/ (Open Access)
-
Advances towards Cell‐Specific Gene Transfection : A Small‐Molecule Approach Allows Order‐of‐Magnitude SelectivityIn: Chemistry - A European Journal Jg. 28 (2022) Nr. 43, S. e202202024Online Volltext: dx.doi.org/; Online Volltext: dx.doi.org/ (Open Access)
-
Computational model predicts protein binding sites of a luminescent ligand equipped with guanidiniocarbonyl-pyrrole groupsIn: Beilstein Journal of Organic Chemistry Jg. 18 (2022) S. 1322 - 1331Online Volltext: dx.doi.org/ (Open Access)
-
Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligandIn: RSC Advances Jg. 12 (2022) Nr. 53, S. 34176 - 34184Online Volltext: dx.doi.org/ (Open Access)
-
GGDEF domain as spatial on-switch for a phosphodiesterase by interaction with landmark protein HubPIn: npj Biofilms and Microbiomes Jg. 8 (2022) Nr. 1, 35Online Volltext: dx.doi.org/ (Open Access)
-
Impact of Secretion-Active Osteoblast-Specific Factor 2 in Promoting Progression and Metastasis of Head and Neck CancerIn: Cancers Jg. 14 (2022) Nr. 9, 2337Online Volltext: dx.doi.org/ (Open Access)
-
Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular TweezersIn: Biomacromolecules Jg. 23 (2022) Nr. 11, S. 4504 - 4518Online Volltext: dx.doi.org/
-
Selective Disruption of Survivin's Protein-Protein Interactions : A Supramolecular Approach Based on GuanidiniocarbonylpyrroleIn: ChemBioChem Jg. 23 (2022) Nr. 5, e202100618Online Volltext: dx.doi.org/ (Open Access)
-
The Taspase1/Myosin1f-axis regulates filopodia dynamicsIn: iScience Jg. 25 (2022) Nr. 6, 104355Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
The Vitamin D Receptor–BIM Axis Overcomes Cisplatin Resistance in Head and Neck CancerIn: Cancers Jg. 14 (2022) Nr. 20, 5131Online Volltext: dx.doi.org/ (Open Access)
-
Amyloid precursor protein elevates fusion of promyelocytic leukemia nuclear bodies in human hippocampal areas with high plaque loadIn: Acta Neuropathologica Communications Jg. 9 (2021) Nr. 1, S. 66Online Volltext: dx.doi.org/ (Open Access)
-
Luminescent Amphiphilic Aminoglycoside Probes to Study TransfectionIn: ChemBioChem Jg. 22 (2021) Nr. 9, S. 1563 - 1567Online Volltext: dx.doi.org/ (Open Access)
-
New tools to probe the protein surface : Ultrasmall gold nanoparticles carry amino acid bindersIn: Journal of Physical Chemistry B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical Chemistry Jg. 125 (2021) Nr. 1, S. 115 - 127Online Volltext: dx.doi.org/ (Open Access)
-
PEGylated sequence-controlled macromolecules using supramolecular binding to target the Taspase1/Importin α interactionIn: Chemical Communications: ChemComm Jg. 57 (2021) Nr. 25, S. 3091 - 3094Online Volltext: dx.doi.org/ (Open Access)
-
Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezersIn: Nature Communications Jg. 12 (2021) Nr. 1, S. 1505Online Volltext: dx.doi.org/ (Open Access)
-
TNF-α-Inhibition Improves the Biocompatibility of Porous Polyethylene Implants In VivoIn: Tissue Engineering and Regenerative Medicine Jg. 18 (2021) Nr. 2, S. 297 - 303Online Volltext: dx.doi.org/ (Open Access)
-
Umbelliferone Decorated Water-soluble Zinc(II) Phthalocyanines : In Vitro Phototoxic Antimicrobial Anti-cancer AgentsIn: Chemistry - A European Journal Jg. 27 (2021) Nr. 59, S. 14672 - 14680Online Volltext: dx.doi.org/ (Open Access)
-
A Supramolecular Stabilizer of the 14-3-3ζ/ERα Protein-Protein Interaction with a Synergistic Mode of ActionIn: Angewandte Chemie International Edition Jg. 132 (2020) Nr. 13, S. 5322 - 5325Online Volltext: dx.doi.org/ (Open Access)
-
Boosting nanotoxicity to combat multidrug-resistant bacteria in pathophysiological environmentsIn: Nanoscale Advances Jg. 2 (2020) Nr. 11, S. 5428 - 5440Online Volltext: dx.doi.org/ (Open Access)
-
Cancer-Cell-Specific Drug Delivery by a Tumor-Homing CPP-Gossypol Conjugate Employing a Tracelessly Cleavable LinkerIn: Chemistry - A European Journal Jg. 26 (2020) Nr. 14, S. 3010 - 3015Online Volltext: dx.doi.org/ (Open Access)
-
Corrigendum to “Biomolecule-corona formation confers resistance of bacteria to nanoparticle-induced killing: Implications for the design of improved nanoantibiotics”In: Biomaterials Jg. 263 (2020) S. 120371Online Volltext: dx.doi.org/
-
Erratum : Nanoparticle binding attenuates the pathobiology of gastric cancer-associated: Helicobacter pyloriIn: Nanoscale Jg. 12 (2020) Nr. 3, S. 2154 - 2155Online Volltext: dx.doi.org/ (Open Access)
-
Functional Disruption of the Cancer-Relevant Interaction between Survivin and Histone H3 with a Guanidiniocarbonyl Pyrrole LigandIn: Angewandte Chemie International Edition Jg. 59 (2020) Nr. 14, S. 5567 - 5571Online Volltext: dx.doi.org/ (Open Access)
-
Lipofection with estrone-based luminophores featuring aggregation-induced emission propertiesIn: RSC Advances Jg. 10 (2020) Nr. 33, S. 19643 - 19647Online Volltext: dx.doi.org/ (Open Access)
-
Mechanisms of nanotoxicity – biomolecule coronas protect pathological fungi against nanoparticle-based eradicationIn: Nanotoxicology Jg. 14 (2020) Nr. 9, S. 1157 - 1174Online Volltext: dx.doi.org/
-
Smart Glycopolymeric Nanoparticles for Multivalent Lectin Binding and Stimuli-Controlled Guest ReleaseIn: Biomacromolecules Jg. 21 (2020) Nr. 6, S. 2356 - 2364Online Volltext: dx.doi.org/
-
Supramolecular subphthalocyanine complexes-cellular uptake and phototoxicityIn: Chemical Communications: ChemComm Jg. 56 (2020) Nr. 55, S. 7653 - 7656Online Volltext: dx.doi.org/
-
The other side of the corona : Nanoparticles inhibit the protease taspase1 in a size-dependent mannerIn: Nanoscale Jg. 12 (2020) Nr. 37, S. 19093 - 19103Online Volltext: dx.doi.org/
-
A Branched Tripeptide with an Anion-Binding Motif as a Novel Delivery Carrier for Efficient Gene TransfectionIn: ChemBioChem Jg. 20 (2019) Nr. 11, S. 1410 - 1416Online Volltext: dx.doi.org/
-
Arginine mimetic appended peptide-based probes for fluorescence turn-on detection of 14-3-3 proteinsIn: Organic and Biomolecular Chemistry Jg. 17 (2019) Nr. 17, S. 4359 - 4363Online Volltext: dx.doi.org/
-
Biomolecule-corona formation confers resistance of bacteria to nanoparticle-induced killing : Implications for the design of improved nanoantibioticsIn: Biomaterials Jg. 192 (2019) S. 551 - 559Online Volltext: dx.doi.org/
-
Is small smarter? Nanomaterial-based detection and elimination of circulating tumor cells : Current knowledge and perspectivesIn: International Journal of Nanomedicine Jg. 14 (2019) S. 4187 - 4209Online Volltext: dx.doi.org/ (Open Access)
-
Non-viral transfection vectors : Are hybrid materials the way forward?In: MedChemComm Jg. 10 (2019) Nr. 10, S. 1692 - 1718Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Protein Dimerization Probed with Site-Specific Attached Single NanoparticlesIn: Biophysical Journal Jg. 116 (2019) Nr. 3, Suppl. 1, S. 284aOnline Volltext: dx.doi.org/ (Open Access)
-
REMOVED: Breaking resistance to nanoantibiotics by overriding corona-dependent inhibition using a pH-switchIn: Materials Today Jg. 26 (2019) S. 19 - 29Online Volltext: dx.doi.org/ (Open Access)
-
Resistance to Nano-Based Antifungals Is Mediated by Biomolecule CoronasIn: ACS Applied Materials & Interfaces Jg. 11 (2019) Nr. 1, S. 104 - 114Online Volltext: dx.doi.org/
-
A dipeptide with enhanced anion binding affinity enables cell uptake and protein deliveryIn: Organic and Biomolecular Chemistry Jg. 16 (2018) Nr. 13, S. 2312 - 2317Online Volltext: dx.doi.org/
-
Expressional analysis of disease-relevant signalling-pathways in primary tumours and metastasis of head and neck cancers.In: Scientific Reports Jg. 8 (2018) Nr. 1, S. 7326Online Volltext: dx.doi.org/ (Open Access)
-
Formation of Twisted β-Sheet Tapes from a Self-Complementary Peptide Based on Novel Pillararene-GCP Host–Guest Interaction with Gene Transfection PropertiesIn: Chemistry - A European Journal Jg. 24 (2018) Nr. 39, S. 9754 - 9759Online Volltext: dx.doi.org/
-
From Supramolecular Vesicles to Micelles : Controllable Construction of Tumor-Targeting Nanocarriers Based on Host–Guest Interaction between a Pillar[5]arene-Based Prodrug and a RGD-Sulfonate GuestIn: Small Jg. 14 (2018) Nr. 52, S. 1803952Online Volltext: dx.doi.org/
-
Human DHEA sulfation requires direct interaction between PAPS synthase 2 and DHEA sulfotransferase SULT2A1In: The Journal of Biological Chemistry (JBC) Jg. 293 (2018) Nr. 25, S. 9724 - 9735Online Volltext: dx.doi.org/ (Open Access)
-
MTOR inhibitor-based combination therapies for pancreatic cancerIn: British Journal of Cancer (BJC) Jg. 118 (2018) S. 366 - 377Online Volltext: dx.doi.org/ (Open Access)
-
Nanomaterial-microbe cross-talk : physicochemical principles and (patho)biological consequencesIn: Chemical Society Reviews Jg. 47 (2018) Nr. 14, S. 5312 - 5337Online Volltext: dx.doi.org/
-
Nanoparticle binding attenuates the pathobiology of gastric cancer-associated Helicobacter pyloriIn: Nanoscale Jg. 10 (2018) Nr. 3, S. 1453 - 1463Online Volltext: dx.doi.org/
-
Nanoparticle decoration impacts airborne fungal pathobiologyIn: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 115 (2018) Nr. 27, S. 7087 - 7092Online Volltext: dx.doi.org/ (Open Access)
-
Nanosized food additives impact beneficial and pathogenic bacteria in the human gut : a simulated gastrointestinal studyIn: npj Science of Food Jg. 2 (2018) S. 22Online Volltext: dx.doi.org/ (Open Access)
-
On the influence of substitution patterns in thioether-based luminophores with aggregation-induced emission propertiesIn: ChemistrySelect Jg. 3 (2018) Nr. 4, S. 985 - 991Online Volltext: dx.doi.org/
-
Simultaneous Rayleigh/Mie and Raman/Fluorescence Characterization of Molecularly Functionalized Colloids by Correlative Single-Particle Real-Time Imaging in SuspensionIn: Analytical Chemistry Jg. 90 (2018) Nr. 1, S. 723 - 728Online Volltext: dx.doi.org/
-
Small Meets Smaller : Effects of Nanomaterials on Microbial Biology, Pathology, and EcologyIn: ACS Nano Jg. 12 (2018) Nr. 7, S. 6351 - 6359Online Volltext: dx.doi.org/
-
Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cellsIn: OncoTarget Jg. 9 (2018) Nr. 45, S. 27835 - 27850Online Volltext: dx.doi.org/ (Open Access)
-
TFIIA transcriptional activity is controlled by a 'cleave-And-run' Exportin-1/Taspase 1-switchIn: Journal of Molecular Cell Biology Jg. 10 (2018) Nr. 1, S. 33 - 47Online Volltext: dx.doi.org/ (Open Access)
-
A systematic structure–activity study of a new type of small peptidic transfection vector reveals the importance of a special oxo-anion-binding motif for gene deliveryIn: ChemBioChem Jg. 18 (2017) Nr. 22, S. 2268 - 2279Online Volltext: dx.doi.org/
-
Aromatic thioethers as novel luminophores with aggregation-induced fluorescence and phosphorescenceIn: Chemistry - A European Journal Jg. 23 (2017) Nr. 55, S. 13660 - 13668Online Volltext: dx.doi.org/
-
Efficient Gene Transfection through Inhibition of β-Sheet (Amyloid Fiber) Formation of a Short Amphiphilic Peptide by Gold NanoparticlesIn: Angewandte Chemie International Edition Jg. 56 (2017) Nr. 28, S. 8083 - 8088Online Volltext: dx.doi.org/
-
Morphology-Dependent Cell Imaging by Using a Self-Assembled Diacetylene Peptide AmphiphileIn: Angewandte Chemie International Edition Jg. 56 (2017) Nr. 46, S. 14526 - 14530Online Volltext: dx.doi.org/
-
Site-Specific SERS Assay for Survivin Protein Dimer : From Ensemble Experiments to Correlative Single-Particle ImagingIn: Small Jg. 13 (2017) Nr. 32, S. 1700802Online Volltext: dx.doi.org/
-
Survivin expression pattern in the intestine of normoxic and ischemic ratsIn: BMC Gastroenterology Jg. 17 (2017) S. 76Online Volltext: dx.doi.org/ (Open Access)
-
An Old Flame Never Dies : Survivin in Cancer and Cellular SenescenceIn: Gerontology Jg. 62 (2016) Nr. 2, S. 173 - 181Online Volltext: dx.doi.org/
-
Cleaving for growth : Threonine aspartase 1-a protease relevant for development and diseaseIn: The FASEB Journal Jg. 30 (2016) Nr. 3, S. 1012 - 1022Online Volltext: dx.doi.org/
-
Guanidiniocarbonyl pyrrole (GCP) conjugated PAMAM-G2, a highly efficient vector for gene delivery: The importance of DNA condensationIn: Chemical Communications: ChemComm Jg. 52 (2016) Nr. 84, S. 12446 - 12449Online Volltext: dx.doi.org/
-
Incorporation of a Non-Natural Arginine Analogue into a Cyclic Peptide Leads to Formation of Positively Charged Nanofibers Capable of Gene TransfectionIn: Angewandte Chemie International Edition Jg. 55 (2016) Nr. 2, S. 598 - 601Online Volltext: dx.doi.org/
-
Introduction of a tailor made anion receptor into the side chain of small peptides allows fine-tuning the thermodynamic signature of peptide-DNA bindingIn: Organic and Biomolecular Chemistry Jg. 14 (2016) Nr. 37, S. 8800 - 8803Online Volltext: dx.doi.org/
-
Membrane tethering of APP c-terminal fragments is a prerequisite for T668 phosphorylation preventing nuclear sphere generationIn: Cellular Signalling Jg. 28 (2016) Nr. 11, S. 1725 - 1734Online Volltext: dx.doi.org/
-
RHAMM splice variants confer radiosensitivity in human breast cancer cell linesIn: OncoTarget Jg. 7 (2016) Nr. 16, S. 21428 - 21440Online Volltext: dx.doi.org/ (Open Access)
-
Taspase1 : a 'misunderstood' protease with translational cancer relevanceIn: Oncogene Jg. 35 (2016) Nr. 26, S. 3351 - 3364Online Volltext: dx.doi.org/
-
A Tailor-Made Specific Anion-Binding Motif in the Side Chain Transforms a Tetrapeptide into an Efficient Vector for Gene DeliveryIn: Angewandte Chemie International Edition Jg. 54 (2015) Nr. 10, S. 2941 - 2944Online Volltext: dx.doi.org/
-
Evolutionary divergence of Threonine Aspartase1 leads to species-specific substrate recognitionIn: Biological Chemistry Jg. 396 (2015) Nr. 4, S. 367 - 376Online Volltext: dx.doi.org/
-
Fly versus man : Evolutionary impairment of nucleolar targeting affects the degradome of Drosophila's Taspase1In: The FASEB Journal Jg. 29 (2015) Nr. 5, S. 1973 - 1985Online Volltext: dx.doi.org/
-
No king without a crown – impact of the nanomaterial-protein corona on nanobiomedicineIn: Nanomedicine: Nanotechnology, Biology, and Medicine Jg. 10 (2015) Nr. 3, S. 503 - 519Online Volltext: dx.doi.org/
-
Sumoylation of HDAC2 promotes NF-κB-dependent gene expressionIn: OncoTarget Jg. 6 (2015) Nr. 9, S. 7123 - 7135Online Volltext: dx.doi.org/ (Open Access)
-
The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancersIn: Cytokine & Growth Factor Reviews Jg. 26 (2015) Nr. 4, S. 405 - 413Online Volltext: dx.doi.org/
-
The nanoparticle biomolecule corona : lessons learned – challenge accepted?In: Chemical Society Reviews Jg. 44 (2015) Nr. 17, S. 6094 - 6121Online Volltext: dx.doi.org/ (Open Access)
-
miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating SurvivinIn: International Journal of Cancer Jg. 136 (2015) Nr. 6, S. 1308 - 1320Online Volltext: dx.doi.org/ (Open Access)
-
Calcium phosphate increases the encapsulation efficiency of hydrophilic drugs (proteins, nucleic acids) into poly(D,L-lactide-co-glycolide acid) nanoparticles for intracellular deliveryIn: Journal of Materials Chemistry B: Materials for Biology and Medicine Jg. 2 (2014) Nr. 41, S. 7250 - 7259Online Volltext: dx.doi.org/ (Open Access)
-
Peptidyl succinimidyl peptides as taspase 1 inhibitorsIn: ChemBioChem Jg. 15 (2014) Nr. 15, S. 2233 - 2237Online Volltext: dx.doi.org/
-
Quantitative profiling of the protein coronas that form around nanoparticlesIn: Nature Protocols Jg. 9 (2014) Nr. 9, S. 2030 - 2044Online Volltext: dx.doi.org/
-
Functional Characterization of Novel Mutations Affecting Survivin (BIRC5)-Mediated Therapy Resistance in Head and Neck Cancer PatientsIn: Human Mutation Jg. 34 (2013) Nr. 2, S. 395 - 404Online Volltext: dx.doi.org/
-
Rapid formation of plasma protein corona critically affects nanoparticle pathophysiologyIn: Nature Nanotechnology Jg. 8 (2013) Nr. 10, S. 772 - 781Online Volltext: dx.doi.org/
-
SIAH proteins : Critical roles in leukemogenesisIn: Leukemia Jg. 27 (2013) Nr. 4, S. 792 - 802Online Volltext: dx.doi.org/
-
Taspase1 : Lizenz zum SchneidenIn: Biospektrum Jg. 19 (2013) Nr. 2, S. 134 - 136Online Volltext: dx.doi.org/
-
Utilizing Combinatorial Chemistry and Rational Design : Peptidic Tweezers with Nanomolar Affinity to DNA Can Be Transformed into Efficient Vectors for Gene Delivery by Addition of a Lipophilic TailIn: Angewandte Chemie International Edition Jg. 52 (2013) Nr. 52, S. 14016 - 14020Online Volltext: dx.doi.org/
-
A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancerIn: OncoTarget Jg. 3 (2012) Nr. 1, S. 31 - 43Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Allosteric inhibition of Taspase1's pathobiological activity by enforced dimerization in vivoIn: The FASEB Journal Jg. 26 (2012) Nr. 8, S. 3421 - 3429Online Volltext: dx.doi.org/
-
Chemico-genetic strategies to inhibit the leukemic potential of threonine aspartase-1In: Blood Cancer Journal Jg. 2 (2012) Nr. 6, S. e77Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Differential regulation of PML–RARα stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1In: The International Journal of Biochemistry & Cell Biology Jg. 44 (2012) Nr. 1, S. 132 - 138Online Volltext: dx.doi.org/
-
Document Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasmIn: PLoS ONE Jg. 7 (2012) Nr. 1, S. e29559Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stressIn: Journal of Molecular Cell Biology Jg. 4 (2012) Nr. 5, S. 284 - 293Online Volltext: dx.doi.org/ (Open Access)
-
Efficient gene delivery into cells by a surprisingly small three-armed peptide ligandIn: Chemical Science Jg. 3 (2012) Nr. 4, S. 996 - 1002Online Volltext: dx.doi.org/
-
Histone deacetylase inhibitors block IFNγ-induced STAT1 phosphorylationIn: Cellular Signalling Jg. 24 (2012) Nr. 7, S. 1453 - 1460Online Volltext: dx.doi.org/
-
Impact of the nanoparticle-protein corona on colloidal stability and protein structureIn: Langmuir Jg. 28 (2012) Nr. 25, S. 9673 - 9679Online Volltext: dx.doi.org/
-
Overexpression of the Catalytically Impaired Taspase1T234V or Taspase1D233A Variants Does Not Have a Dominant Negative Effect in T(4;11) Leukemia CellsIn: PLoS ONE Jg. 7 (2012) Nr. 5, S. e34142Online Volltext: dx.doi.org/ Online Volltext (Open Access)
-
Targeting Taspase1 for Cancer Therapy—LetterIn: Cancer Research Jg. 72 (2012) Nr. 11, S. 2912Online Volltext: dx.doi.org/
-
Bioassays to Monitor Taspase1 Function for the Identification of Pharmacogenetic Inhibitors.In: PLoS ONE Jg. 6 (2011) Nr. 5, S. e18253Online Volltext: dx.doi.org/ (Open Access)
-
Cell-based analysis of structure-function activity of threonine aspartase 1.In: The Journal of Biological Chemistry (JBC) Jg. 286 (2011) Nr. 4, S. 3007 - 3017Online Volltext: dx.doi.org/
-
Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona : a comprehensive quantitative proteomic analysisIn: ACS Nano Jg. 5 (2011) Nr. 9, S. 7155 - 7167Online Volltext: dx.doi.org/
-
The Importin-Alpha/Nucleophosmin Switch Controls Taspase1 Protease Function.In: Traffic: The International Journal of Intracellular Transport Jg. 12 (2011) Nr. 6, S. 703 - 714Online Volltext: dx.doi.org/
-
The heterodimerization domains of MLL-FYRN and FYRC-are potential target structures in t(4;11) leukemia.In: Leukemia Jg. 25 (2011) Nr. 4, S. 663 - 670Online Volltext: dx.doi.org/
-
An otoprotective role for the apoptosis inhibitor protein survivinIn: Cell Death and Disease Jg. 1 (2010) Nr. 51, e51Online Volltext: dx.doi.org/ (Open Access)
-
An update on the pathobiological relevance of nuclear receptors for cancers of the head and neckIn: Histology and Histopathology Jg. 25 (2010) Nr. 8, S. 1093 - 1104Online Volltext: dx.doi.org/
-
Cloning and functional characterization of the guinea pig apoptosis inhibitor protein SurvivinIn: Gene Jg. 469 (2010) Nr. 1-2, S. 9 - 17Online Volltext: dx.doi.org/
-
Expression analysis suggests a potential cytoprotective role of Birc5 in the inner earIn: Molecular and Cellular Neuroscience (MCN) Jg. 45 (2010) Nr. 3, S. 297 - 305Online Volltext: dx.doi.org/
-
Nuclear receptors in head and neck cancer: current knowledge and perspectives.In: International Journal of Cancer Jg. 126 (2010) Nr. 4, S. 801 - 809
-
A phosphorylation-acetylation switch regulates STAT1 signaling.In: Genes & development : a journal of cellular and molecular biology Jg. 23 (2009) Nr. 2, S. 223 - 235
-
Inducible NO synthase confers chemoresistance in head and neck cancer by modulating survivinIn: International Journal of Cancer Jg. 124 (2009) Nr. 9, S. 2033 - 2041
-
Prognostic and therapeutic potential of nuclear receptors in head and neck squamous cell carcinomas.In: Journal of Oncology (2009) 349205Online Volltext: dx.doi.org/
-
Similar regulation of human inducible nitric oxide synthase (iNOS) expression by different isoforms of the RNA binding protein AUF1In: The Journal of Biological Chemistry (JBC) Jg. 284 (2009) Nr. 5, S. 2755 - 2766
-
Translocation biosensors – cellular system integrators to dissect CRM1-dependent nuclear export by chemicogenomics.In: Sensors Jg. 9 (2009) Nr. 7, S. 5423 - 5445Online Volltext: dx.doi.org/ (Open Access)
-
Histone deacetylase inhibitors and hydroxyurea modulate the cell cycle and cooperatively induce apoptosis.In: Oncogene : an international journal Jg. 27 (2008) Nr. 6, S. 732 - 740
-
NO signaling confers cytoprotectivity through the survivin network in ovarian carcinomasIn: Cancer Research Jg. 68 (2008) Nr. 13, S. 5159 - 5166
-
Phosphorylation of nm23-H1 by CKI induces its complex formation with h-prune and promotes cell motilityIn: Oncogene Jg. 27 (2008) Nr. 13, S. 1853 - 1864Online Volltext: dx.doi.org/
-
Therapeutic potential of nuclear receptors.In: Expert Opinion on Therapeutic Patents Jg. 18 (2008) Nr. 8, S. 861 - 888
-
Dynamic Intracellular Survivin as an Early Prognostic Marker in Oral Squamous Cell Carcinomas : Underlying Molecular Mechanism and PotentialIn: The Journal of Pathology Jg. 211 (2007) Nr. 5, S. 532 - 540
-
Dynamic survivin in head and neck cancer: Molecular mechanism and therapeutic potentialIn: International Journal of Cancer Jg. 121 (2007) Nr. 6, S. 1169 - 1174
-
Nuclear and Cytoplasmic Survivin: Molecular Mechanism, Prognostic, and Therapeutic Potential.In: Cancer Research Jg. 67 (2007) Nr. 13, S. 5999 - 6002
-
Nuclear export is essential for the tumor-promoting activity of survivinIn: The FASEB Journal: the official journal of the Federation of American Societies for Experimental Biology / Experimental Biology ; Transforming the future through science ; Chicago, April 22-26, 2017 Jg. 21 (2007) Nr. 1, S. 207 - 216
-
Survivin's Dual Role - An Export's View.In: Cell Cycle Jg. 6 (2007) Nr. 5, S. 518 - 521
-
The Role of Survivin for Radiation Therapy : Prognostic and Predictive Factor and Therapeutic TargetIn: Strahlentherapie und Onkologie: Journal of Radiation Oncology, Biology, Physics Jg. 183 (2007) Nr. 11, S. 593 - 599Online Volltext: dx.doi.org/
-
The differentiation antigen NY-BR-1 is a potential target for antibody based therapies in breast cancer.In: International Journal of Cancer Jg. 120 (2007) Nr. 12, S. 2635 - 2642
-
The survivin splice variant survivin-3B is cytoprotective and can function as a chromosomal passenger complex proteinIn: Cell Cycle Jg. 6 (2007) Nr. 12, S. 1502 - 1509Online Volltext: dx.doi.org/
-
Acetylation of Stat1 modulates NF-kB activityIn: Genes & development : a journal of cellular and molecular biology Jg. 20 (2006) Nr. 4, S. 473 - 485
-
Nucleocytoplasmic shuttling and the biological activity of mouse survivin are regulated by an active nuclear export signalIn: Traffic: The International Journal of Intracellular Transport Jg. 7 (2006) Nr. 11, S. 1461 - 1472Online Volltext: dx.doi.org/
-
Targeted induction of apoptosis by chimeric granzyme B fusion proteins carrying antibody and growth factor domains for cell recognition.In: Cell death & differentiation : D & D ; cdd Jg. 13 (2006) Nr. 4, S. 576 - 585
-
The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and function.In: EMBO Reports Jg. 7 (2006) Nr. 12, S. 1259 - 1265
-
Development of an autofluorescent translocation biosensor system to investigate protein-protein interactions in living cellsIn: Analytical Chemistry Jg. 77 (2005) Nr. 15, S. 4815 - 4820Online Volltext: dx.doi.org/
-
Nuclear Export Is Evolutionarily Conserved in CVC Paired-Like Homeobox Proteins and Influences Protein Stability, Transcriptional Activation, and Extracellular Secretion.In: Molecular and Cellular Biology (MCB) Jg. 6 (2005) Nr. 7, S. 594 - 606
-
Translocation Biosensors to Study Signal-Specific Nucleo-Cytoplasmic Transport, Protease Activity and Protein–Protein InteractionsIn: Traffic: The International Journal of Intracellular Transport Jg. 6 (2005) Nr. 7, S. 594 - 606
-
Therapy-Related Investigations On the DNA Degrading Effect of Noble Metal Nanoparticles in Proton Therapy Using Liquid and Gel-Based PhantomsIn: Medical Physics Jg. 49 (2022) Nr. 6, S. E598 - E599
-
'Small meets smaller' : impact of nanomaterials on microbiota
43rd FEBS Congress, Biochemistry Forever, July 7‐12, 2018, Prague,In: FEBS Open Bio Jg. 8 (2018) Nr. Suppl. S1: 43rd FEBS Congress, Biochemistry Forever, Prague, Czech Republic, July 7‐12, 2018, S. 49 - 50Online Volltext: dx.doi.org/ (Open Access) -
Translocation Biosensors—Versatile Tools to Probe Protein Functions in Living CellsIn: High Content Screening 2018, S. 195 - 210Online Volltext: dx.doi.org/
-
Analysis of HDACi-induced changes in chromosomal passenger complex localizationIn: HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols / Krämer, Oliver H. (Hrsg.) 2017, S. 47 - 59Online Volltext: dx.doi.org/
-
Bio-Nano InteractionsIn: Adverse effects of engineered nanomaterials: exposure, toxicology, and impact on human health / Fadeel, Bengt; Pietroiusti, Antonio; Shvedova, Anna (Hrsg.) 2017, S. 1 - 12Online Volltext: dx.doi.org/