ZMB Member Katja Ferenz

ZMB Member
Katja Ferenz

Next ZMB-Member
Katja Ferenz portrait
© K.Ferenz

Jun.-Prof. Dr. Katja Ferenz

Group

Institute of Physiology

University Hospital Essen
Virchowstr. 171
45147 Essen

Research Overview

Development of perfluorocarbon-based artificial oxygen carriers (AOCs)

  • Perfluorocarbon-based AOCs as blood substitutes
  • Perfluorocarbon-based AOCs to improve quality of organs prior to transplantation
  • Treatment of decompression sickness with perfluorocarbon-based AOCs

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Publications

    Journal articles

  • Feng, Huayang; Linders, Jürgen; Cantore, Miriam; Fabrizi, Jonas; Kirsten, Annika; Myszkowska, Sascha; Hillen, Eva; Uteschil, Florian; Buchholz, Sebastian; Hermsen, Andrea; Garvin, Maria Davila; Ferenz, Katja; Mayer, Christian
    Cross-linked Triblock Peptide Capsules as Potential Oxygen Carriers
    In: ChemistryOpen Vol. 13 (2024) Nr. 4, e202300282
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Dušková, Tereza; Čermák, Jan; Cantore, Miriam; Greguš, Viktor; Sydow, Jan-Eric; Henych, Jiří; Ferenz, Katja
    Harnessing Perfluorocarbon-Based nanocarriers for Rhodium(III) NHC complex Delivery : Synthesis, Characterization, and cytotoxicity evaluation
    In: Inorganica Chimica Acta Vol. 576 (2024) 122471
    Online Full Text: dx.doi.org/
  • Semmler, Anna-Lena; Köhler, Jan-Philipp; Regolien, Lara; Bayer, Franziska; Polyansky, Nikolay; Gradhand, Elise; von Knethen, Andreas; Zacharowski, Kai; Nocke, Fabian; Ferenz, Katja B.; Schwäble, Joachim; Bonig, Halvard; Herrmann, Eva; Hornung, Isabelle; Steinbicker, Andrea U.
    Selective red blood cell depletion by apheresis in sheep causes severe normovolemic anemia
    In: Current Research in Translational Medicine Vol. 72 (2024) Nr. 4, 103463
    Online Full Text: dx.doi.org/
  • Pizanis, Nikolaus; Dimitriou, Alexandros Merkourios; Koch, Achim; Lüdike, Peter; Papathanasiou, Maria; Rassaf, Tienush; Ruhparwar, Arjang; Schmack, Bastian; Weymann, Alexander; Ferenz, Katja; Kamler, Markus
    Introduction of machine perfusion of donor hearts in a single center in Germany
    In: International Journal of Cardiology (IJC) Heart & Vasculature Vol. 47 (2023) 101233
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Rother, Tamina; Horgby, Carina; Schmalkuche, Katharina; Burgmann, Jonathan M.; Nocke, Fabian; Jägers, Johannes; Schmitz, Jessica; Bräsen, Jan Hinrich; Cantore, Miriam; Zal, Franck; Ferenz, Katja B.; Blasczyk, Rainer; Figueiredo, Constanca
    Oxygen carriers affect kidney immunogenicity during ex-vivo machine perfusion
    In: Frontiers in Transplantation Vol. 2 (2023) 1183908
    Online Full Text: dx.doi.org/ (Open Access)
  • Hester, Sarah; Ferenz, Katja; Adick, Annika; Kakalias, Christos; Mulac, Dennis; Azhdari, Suna; Langer, Klaus
    Triglyceride-filled albumin-based nanocapsules: A promising new system to avoid discarding poorly water-soluble drug candidates
    In: International Journal of Pharmaceutics Vol. 646 (2023) 123454
    Online Full Text: dx.doi.org/
  • Jägers, Johannes; Kirsch, Michael; Cantore, Miriam; Karaman, Ozan; Ferenz, Katja
    Artificial oxygen carriers in organ preservation : Dose dependency in a rat model of ex-vivo normothermic kidney perfusion
    In: Artificial Organs Vol. 46 (2022) Nr. 9, pp. 1783 - 1793
    Online Full Text: dx.doi.org/ (Open Access)
  • Jaegers, Johannes; Haferkamp, Sven; Arnolds, Oliver; Moog, Daniel; Wrobeln, Anna; Nocke, Fabian; Cantore, Miriam; Pütz, Stefanie; Hartwig, Anne; Franzkoch, Rico; Psathaki, Olympia Ekaterini; Jastrow, Holger; Schauerte, Carsten; Stoll, Raphael; Kirsch, Michael; Ferenz, Katja
    Deciphering the Emulsification Process to Create an Albumin-Perfluorocarbon-(o/w) Nanoemulsion with High Shelf Life and Bioresistivity
    In: Langmuir Vol. 38 (2022) Nr. 34, pp. 10351 - 10361
    Online Full Text: dx.doi.org/
  • Hester, Sarah; Ferenz, Katja Bettina; Eitner, Susanne; Langer, Klaus
    Development of a lyophilization process for long-term storage of albumin-based perfluorodecalin-filled artificial oxygen carriers
    In: Pharmaceutics Vol. 13 (2021) Nr. 4, 584
    Online Full Text: dx.doi.org/ (Open Access)
  • Jägers, Johannes; Wrobeln, Anna; Ferenz, Katja
    Perfluorocarbon-based oxygen carriers : From physics to physiology
    In: Pflügers Archiv: European Journal of Physiology Vol. 473 (2021) Nr. 2, pp. 139 - 150
    Online Full Text: dx.doi.org/ (Open Access)
  • Wrobeln, Anna; Jägers, Johannes; Quinting, Theresa; Schreiber, Timm; Kirsch, Michael; Fandrey, Joachim; Ferenz, Katja
    Albumin-derived perfluorocarbon-based artificial oxygen carriers can avoid hypoxic tissue damage in massive hemodilution
    In: Scientific Reports Vol. 10 (2020) Nr. 1, pp. 11950
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Mayer, Dirk; Guerrero, FranÇois; Goanvec, Christelle; Hetzel, Lisa; Linders, Jürgen; Ljubkovic, Marko; Kreczy, Alfons; Mayer, Christian; Kirsch, Michael; Ferenz, Katja
    Prevention of Decompression Sickness by Novel Artificial Oxygen Carriers
    In: Medicine & Science in Sports & Exercise Vol. 52 (2020) Nr. 10, pp. 2127 - 2135
    Online Full Text: dx.doi.org/
  • Schakowski, Kai Melvin; Linders, Jürgen; Ferenz, Katja; Kirsch, Michael
    Synthesis and characterisation of aqueous haemoglobin-based microcapsules coated by genipin-cross-linked albumin
    In: Journal of Microencapsulation Vol. 37 (2020) Nr. 3, pp. 193 - 204
    Online Full Text: dx.doi.org/; Online Full Text: dx.doi.org/ (Open Access)
  • Stokvis, A.; Cantore, M.; Fandrey, Joachim; Ferenz, Katja;
    Application and effects of artificial oxygen carriers in pO2-controlled kidney cell culture
    98th Meeting of the German Physiological Society, 30 September ‐ 2 October 2019, Ulm, Germany,
    In: Acta Physiologica Vol. 227 (2019) Nr. S719, B 04-3
    Online Full Text
  • Ferenz, Katja; Steinbicker, Andrea U.
    Artificial Oxygen Carriers-Past, Present, and Future-a Review of the Most Innovative and Clinically Relevant Concepts
    In: The Journal of Pharmacology and Experimental Therapeutics Vol. 369 (2019) Nr. 2, pp. 300 - 310
    Online Full Text: dx.doi.org/ (Open Access)
  • Mayer, Dirk; Ferenz, Katja
    Perfluorocarbons for the treatment of decompression illness : how to bridge the gap between theory and practice
    In: European Journal of Applied Physiology Vol. 119 (2019) Nr. 11/12, pp. 2421 - 2433
    Online Full Text: dx.doi.org/ (Open Access)
  • Mayer, D.; Guerrero, Francois; Goanvec, C.; Kreczy, A.; Ljubkovic, M.; Mayer, Christian; Kirsch, Michael; Ferenz, Katja;
    Prevention of decompression illness : recently developed albumin-derived perfluorocarbon-based nanocapsules prove effectiveness on a clinical, biochemical and histological level
    98th Meeting of the German Physiological Society, 30 September ‐ 2 October 2019, Ulm, Germany,
    In: Acta Physiologica Vol. 227 (2019) Nr. S719, B 04-12
    Online Full Text
  • Leu, Tristan; Schützhold, Vera; Fandrey, Joachim; Ferenz, Katja
    When the brain yearns for oxygen
    In: Neurosignals Vol. 27 (2019) Nr. 1, pp. 50 - 61
    Online Full Text: dx.doi.org/ (Open Access)
  • Köhler, Jannis; Ruschke, Jegor; Ferenz, Katja; Esen, Cemal; Kirsch, Michael; Ostendorf, Andreas
    Investigation of albumin-derived perfluorocarbon-based capsules by holographic optical trapping
    In: Biomedical Optics Express Vol. 9 (2018) Nr. 2, pp. 743 - 754
    Online Full Text: dx.doi.org/ (Open Access)
  • Wrobeln, Anna; Laudien, Julia; Groß-Heitfeld, Christoph; Linders, Jürgen; Mayer, Christian; Wilde, Benjamin; Knoll, Tanja; Naglav, Dominik; Kirsch, Michael; Ferenz, Katja
    Albumin-derived perfluorocarbon-based artificial oxygen carriers : A physico-chemical characterization and first in vivo evaluation of biocompatibility
    In: European Journal of Pharmaceutics and Biopharmaceutics Vol. 115 (2017) pp. 52 - 64
    Online Full Text: dx.doi.org/
  • Wrobeln, Anna; Schlüter, Klaus D.; Linders, Jürgen; Zähres, Manfred; Mayer, Christian; Kirsch, Michael; Ferenz, Katja
    Functionality of albumin-derived perfluorocarbon-based artificial oxygen carriers in the Langendorff-heart
    In: Artificial Cells, Nanomedicine and Biotechnology Vol. 45 (2017) Nr. 4, pp. 723 - 730
    Online Full Text: dx.doi.org/
  • Laudien, Julia; Groß-Heitfeld, Christoph; Mayer, Christian; de Groot, Herbert; Kirsch, Michael; Ferenz, Katja
    Perfluorodecalin-filled Poly(n-butyl-cyanoacrylate) nanocapsules as potential artificial oxygen carriers : preclinical safety and biocompatibility
    In: Journal of Nanoscience and Nanotechnology Vol. 15 (2015) Nr. 8, pp. 5637 - 5648
    Online Full Text: dx.doi.org/
  • Stephan, Claudia; Schlawne, Carolin; Graß, Stefan; Waack, Indra N.; Ferenz, Katja; Bachmann, Michael; Barnert, Sabine; Schubert, Rolf; Bastmeyer, Martin; de Groot, Herbert; Mayer, Christian
    Artificial oxygen carriers based on perfluorodecalin-filled poly(n-butyl-cyanoacrylate) nanocapsules
    In: Journal of Microencapsulation Vol. 31 (2014) Nr. 3, pp. 284 - 292
    Online Full Text: dx.doi.org/
  • Laudien, Julia; Naglav, Dominik; Groß-Heidfeld, Christian; Ferenz, Katja; de Groot, Herbert; Mayer, Christian; Schulz, Stephan; Schnepf, Andreas; Kirsch, Michael
    Perfluorodecalin-soluble fluorescent dyes for the monitoring of circulating nanocapsules with intravital fluorescence microscopy
    In: Journal of Microencapsulation Vol. 31 (2014) Nr. 8, pp. 738 - 745
    Online Full Text: dx.doi.org/ Online Full Text (Open Access)
  • Ferenz, Katja; Waack, Indra N.; Laudien, Julia; Mayer, Christian; Bröcker-Preuß, Martina; de Groot, Herbert; Kirsch, Michael
    Safety of poly (ethylene glycol)-coated perfluorodecalin-filled poly (lactide-co-glycolide) microcapsules following intravenous administration of high amounts in rats
    In: Results in Pharma Sciences Vol. 4 (2014) pp. 8 - 18
    Online Full Text: dx.doi.org/ (Open Access)
  • Teloh, Johanna K.; Ferenz, Katja; Petrat, Frank; Mayer, Christian; de Groot, Herbert
    Acid-Base and electrolyte status during normovolemic hemodilution with succinylated gelatin or HES-Containing volume replacement solutions in rats
    In: PLoS ONE Vol. 8 (2013) Nr. 9, pp. e72848
    Online Full Text: dx.doi.org/ (Open Access)
  • Ferenz, Katja; Waack, Indra N.; Mayer, Christian; de Groot, Herbert; Kirsch, Michael
    Long-circulating poly(ethylene glycol)-coated poly(lactid-co-glycolid) microcapsules as potential carriers for intravenously administered drugs
    In: Journal of Microencapsulation Vol. 30 (2013) Nr. 7, pp. 632 - 642
    Online Full Text: dx.doi.org/
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