Early Career Researchers
Open Positions
We are always seeking highly motivated and qualified individuals.
If you are interested in the projects of our CRC you can look for open position here.
Project Area A
Biology and Molecular Oncology
Doctoral Researcher Christian Cozma
Investigation of molecular mechanisms that regulate the organization and dynamics of microtubules during cell division
Doctoral Researcher Richard Pleuger
Recruitment of mitotic regulators to the budding yeast kinetochore
Doctoral Researcher Jason Mak
Investigation of force sensing mechanism at the kinetochore-mirotubule interface
Doctoral Researcher Alexander Kroening
Biochemical and functional dissection of p97-cofactor interactions
Doctoral Researcher Daniella Munro
The role of VCP/p97 in cellular stress responses and checkpoint signalling
Postdoc Maike Reinders (former Giesing)
A rapid degradation approach for VCP/p97 cofactor proteins and its application in analyzing Ataxin-3 function in lysophagy
Doctoral Researcher Cole Bourque
High-resolution structural analysis and reconstruction of the Dam1 complex and associated proteins
Doctoral Researcher Eda Şamiloğlu Tengirşek
Structural Biology in Cellular Compartments: Peroxisomes
Doctoral Researcher Eman Zaffar
Role of MTBP-CDK8 in regulating replication origin firing in higher eukaryotes
Doctoral Researcher Bastian Möllers
Biochemical and Cell Biological Characterization of the HTRA1-p97 Protein Complex
Doctoral Researcher Lana Buzuk
How are Golgi Quality Control Substrates Targeted to the Lysosome for Degradation?
Doctoral Researcher Gina Simon
The role of FAM129A in Golgi stress and cell state transitions
Doctoral Researcher Katarina Blazevic
Investigating the subcellular Rho activity dynamics during cell cycle transitions and the control by distinct GEF families
Postdoc Kristina Mrug
Regulation of the pulsatory contraction signal network dynamics during cell division
Doctoral Researcher Nicole Schrenke
The switch of Rho contractility signaling in drug resistant melanoma
Doctoral Researcher Alexandra Hommel
Rapid degradation of KDM5B induces a cell-stress-related vulnerability in melanoma cells
Doctoral Researcher Egor Pavlenko
Functional characterization of PRC2 dimerization on chromatin and structural analyses of mitochondrial complex formation of Apoptosis-inducing factor 1
Doctoral Researcher Till Rüngeler
Structure and regulatory interactions of human histone demethylase KDM5B
Clinician Scientist Johanna A. Seier
Epigenetische Kontrolle des Interferon Signalweges und Th1-Typ Chemokinexpression im MYCN-amplifizierten Neuroblastom
Doctoral Researcher Shannon Conroy
Compound based approach inhibiting the metastatic cell state transition in pancreatic cancer
Doctoral Researcher Sebastian Urban
Unraveling the molecular function of USP7 in PDAC: Impact on Metabolism and EMT Dynamics
Project Area B
Chemical Biology
Doctoral Researcher Lukas Schrapp
Investigations on modulation of cancer cell migration via small molecules
PhD Doctoral Researcher Nikolas Klink
Synthesis and Evaluation of PROTACs for Degradation of Deubiquitinases
PhD Doctoral Researcher Martin Schwalm
Hijacking the ubiquitin and autophagy system for the development of chemical degraders
Doctoral Researcher Janik Weckesser
Development of heterobifunctional molecules using new E3 ligase ligands
Doctoral Researcher Julio Cesar Vieyto Nuñez
Computational studies of enzymes and supramolecular ligands
Project Area Z
Central Services
Alumni
Postdoc Alexander Dudziak
Biochemical and genetic analysis of Dam1c ring assembly at the budding yeast kinetochore
PhD student Pinki Gahlot
Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH
Alumni Milena Parlak
TopBP1 loads GINS onto the Metazoan Mcm2-7 Helicase during Replication Origin Firing
Alumni Bilal Tetik
Bipartite GINS binding mode of TopBP1 to activate the metazoan Mcm2-7 replicative helicase
Alumni Birte Hagemeier
Mechanistic insights into the interactions of HTRA1 with pathological Tau species
Alumni Savina Abraham-Pol
Stress-induced Golgi remodelling revealed by chemical biology stress models
Alumni Beatrice Thier
Treatment-induced sculpting of melanoma phenotype and immunogenicity – Impact on resistance to CD8 T cells
Alumni Mirko Schmidt
Design, Synthesis and Biological Evaluation of Tool Compounds for the Cellular Investigation of Deubiquitinases
PhD student Stefan Kleine
Synthese und biologische Validierung hetero-bifunktionaler Moleküle zum gerichteten Proteinabbau in Bakterien
PhD student David Podlesainski
Elucidation of the mode-of-action of the anti-tubercular Callyaerins