Platelet depletion does not alter long-term functional outcome after cerebral ischaemia in mice
Brain, Behavior, & Immunity - Health; 2022-07-21; (): ; doi:10.1016/j.bbih.2022.100493

Rebecca D. Steubing, Fabian Szepanowski, Christina David, Ayan Mohamud Yusuf, Stine Mencl, Anne-Kathrin Mausberg, Harald F. Langer, Manuela Sauter, Cornelius Deuschl, Michael Forsting, Anke C. Fender, Dirk M. Hermann, Ana I. Casas, Friederike Langhauser, Christoph Kleinschnitz



Design and Functional Characterization of HIV-1 Envelope Protein-Coupled T Helper Liposomes
Pharmaceutics; 2022-06-30; 14(7): 1385; doi:10.3390/pharmaceutics14071385
https://www.mdpi.com/1999-4923/14/7/1385
Dominik Damm , Ehsan Suleiman , Hannah Theobald , Jannik T. Wagner , Mirjam Batzoni , Bianca Ahlfeld (née Kohlhauser) , Bernd Walkenfort , Jens-Christian Albrecht , Jidnyasa Ingale , Lifei Yang , Mike Hasenberg , Richard T. Wyatt , Karola Vorauer-Uhl , Klaus Überla and Vladimir Temchura


https://pubmed.ncbi.nlm.nih.gov/35697379/
Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity
Journal for ImmunoTherapie of Cancer; 2022-06-23; 10(6): ; doi:10.1136/jitc-2021-003863
https://jitc.bmj.com/content/10/6/e003863
Beatrice Thier, Fang Zhao, Simone Stupia, Alicia Brüggemann, Johannes Koch, Nina Schulze, Susanne Horn, Christoph Coch, Gunther Hartmann 5, Antje Sucker, Dirk Schadendorf, Annette Paschen


https://pubmed.ncbi.nlm.nih.gov/33784074/
Gold Nanorods Induce Endoplasmic Reticulum Stress and Autocrine Inflammatory Activation in Human Neutrophils
ACS Nano; 2022-06-23; 16(4): ; doi:10.1021/acschembio.0c00757
https://pubs.acs.org/doi/full/10.1021/acsnano.2c03586
Ronja Schirrmann, Michael Erkelenz, Kim Lamers, Oliver Sritharan, Milen Nachev, Bernd Sures, Sebastian Schlücker, and Sven Brandau



Bacteria (E. coli ) take up ultrasmall gold nanoparticles (2 nm) as shown by different optical microscopic techniques (CLSM, SIM, STORM)
Nano Select; 2022-06-14; (): ; doi:10.1002/nano.202200049
https://onlinelibrary.wiley.com/doi/full/10.1002/nano.202200049
Nataniel Bia?as,Viktoriya Sokolova,Selina Beatrice van der Meer,Torben Knuschke,Tatjana Ruks,Kai Klein,Astrid M. Westendorf,Matthias Epple


https://pubmed.ncbi.nlm.nih.gov/35697379/
Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity
Journal for ImmunoTherapie of Cancer; 2022-06-10; 6(): ; doi:10.1136/jitc-2021-003863
https://jitc.bmj.com/content/10/6/e003863.long
Beatrice Thier, Fang Zhao, Simone Stupia, Alicia Brüggemann, Johannes Koch, Nina Schulze, Susanne Horn, Christoph Coch, Gunther Hartmann, Antje Sucker, Dirk Schadendorf, Annette Paschen


https://pubmed.ncbi.nlm.nih.gov/35650266/
Persister state-directed transitioning and vulnerability in melanoma.
Nature Communications; 2022-06-01; 13(1): 3055; doi:https://doi.org/10.1038/s41467-022-30641-9
https://doi.org/10.1038/s41467-022-30641-9
Chauvistré H, Shannan B, Daignault-Mill SM, Ju RJ, Picard D, Egetemaier S, Váraljai R, Gibhardt CS, Sechi A, Kaschani F, Keminer O, Stehbens SJ, Liu Q, Yin X, Jeyakumar K, Vogel FCE, Krepler C, Rebecca VW, Kubat L, Lueong SS, Forster J, Horn S, Remke M, Ehrmann M, Paschen A, Becker JC, Helfrich I, Rauh D, Kaiser M, Gul S, Herlyn M, Bogeski I, Rodríguez-López JN, Haass NK, Schadendorf D, Roesch A.


https://pubmed.ncbi.nlm.nih.gov/35609021/
Long-term treatment with chloroquine increases lifespan in middle-aged male mice possibly via autophagy modulation, proteasome inhibition and glycogen metabolism.
Aging; 2022-05-23; 14(): ; doi:10.18632/aging.204069
https://www.aging-us.com/article/204069/text
Doeppner TR, Coman C, Burdusel D, Ancuta DL, Brockmeier U, Pirici DN, Yaoyun K, Hermann DM, Popa-Wagner A


https://pubmed.ncbi.nlm.nih.gov/35565295/
RB1-Negative Retinal Organoids Display Proliferation of Cone Photoreceptors and Loss of Retinal Differentiation
Cancers; 2022-04-26; 14(9): 2166; doi:10.3390/cancers14092166

Kanber D, Woesfeld J, Döpper H, Bozet M, Brenzel A, Altmüller J, Kilpert D, Pommerenke C, Steenpass L


https://pubmed.ncbi.nlm.nih.gov/34530440/
Sublamina-Specific Dynamics and Ultrastructural Heterogeneity of Layer 6 Excitatory Synaptic Boutons in the Adult Human Temporal Lobe Neocortex.
Cerebral Cortex; 2022-04-20; 32(9): 1840-1865; doi: https://doi.org/10.1093/cercor/bhab315
https://academic.oup.com/cercor/advance-article/doi/10.1093/cercor/bhab315/6371350
Schmuhl-Giesen S, Rollenhagen A, Walkenfort B, Yakoubi R, Sätzler K, Miller D, von Lehe M, Hasenberg M, Lübke JHR



Efficient Small Extracellular Vesicles (EV) Isolation Method and Evaluation of EV-Associated DNA Role in Cell–Cell Communication in Cancer
Cancers; 2022-04-20; 14(9): 2068; doi:https://doi.org/10.3390/cancers14092068
https://doi.org/10.3390/cancers14092068
Chetty VK, Ghanam J, Anchan S, Reinhardt K, Brenzel A, Gelléri M, Cremer C, Grueso-Navarro E, Schneider M, von Neuhoff N, Reinhardt D, Jablonska J, Nazarenko I, Thakur BK


https://pubmed.ncbi.nlm.nih.gov/34751438/
SIRT1-mediated deacetylation of FOXO3a transcription factor supports pro-angiogenic activity of interferon-deficient tumor-associated neutrophils
International Journal of cancer; 2022-04-01; 150(7): 1198-1211; doi:10.1002/ijc.33871
https://onlinelibrary.wiley.com/doi/10.1002/ijc.33871
Bordbari S, Mörchen B, Pylaeva E, Siakaeva E, Spyra I, Domnich M, Droege F, Kanaan O, Lang KS, Schadendorf D, Lang S, Helfrich I, Jablonska J



Free flow electrophoresis allows quick and reproducible preparation of extracellular vesicles from conditioned cell culture media
Extracellular Vesicles and Circulating Nucleic Acids; 2022-03-22; 3(): 31-48; doi:
https://evcna.com/article/view/4702
Staubach S, Tertel T, Walkenfort B, Buschmann D, Pfaffl MW, Weber G, Giebel B


https://pubmed.ncbi.nlm.nih.gov/35289361/
Inhibition of azole-resistant Aspergillus fumigatus biofilm at various formation stages by antifungal drugs, including olorofim
Journal of Antimicrobial Chemotherapy; 2022-03-15; (): ; doi:10.1093/jac/dkac062
https://academic.oup.com/jac/advance-article/doi/10.1093/jac/dkac062/6548677
Kirchhoff L, Dittmer S, Furnica DT, Buer J, Steinmann E, Rath PM, Steinmann J


https://pubmed.ncbi.nlm.nih.gov/34779257/
An Early Wave of Macrophage Infiltration Intertwined with Antigen-Specific Proinflammatory T Cells and Browning of Adipose Tissue Characterizes the Onset of Orbital Inflammation in a Mouse Model of Graves' Orbitopathy.
Thyroid; 2022-03-01; 32(3): 283-293; doi:10.1089/thy.2021.0464
https://www.liebertpub.com/doi/10.1089/thy.2021.0464?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed
Philipp S, Horstmann M, Hose M, Daser A, Görtz GA, Jesenek C, Flögel U, Hansen W, Bechrakis N, Banga JPS, Eckstein A, Berchner-Pfannschmidt U


https://pubmed.ncbi.nlm.nih.gov/35251021/
Reactivity of NK Cells Against Ovarian Cancer Cells Is Maintained in the Presence of Calcium Phosphate Nanoparticles
Frontiers in Immunology; 2022-02-18; 13(830938): ; doi:https://doi.org/10.3389/fimmu.2022.830938
https://www.frontiersin.org/articles/10.3389/fimmu.2022.830938/full
Hrvat A, Schmidt M, Obholzer M, Benders S, Kollenda S, Horn PA, Epple M, Brandau S, Mallmann-Gottschalk N


https://pubmed.ncbi.nlm.nih.gov/35159369/
Induction of Survival of Motor Neuron (SMN) Protein Deficiency in Spinal Astrocytes by Small Interfering RNA as an In Vitro Model of Spinal Muscular Atrophy
Cells; 2022-02-05; 11(3): 558; doi:10.3390/cells11030558
https://www.mdpi.com/2073-4409/11/3/558/htm
Leo M, Schmitt LI, Fleischer M, Steffen R, Osswald C, Kleinschnitz C, Hagenacker T


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834272/
Distinct Actions of the Thyroid Hormone Transporters Mct8 and Oatp1c1 in Murine Adult Hippocampal Neurogenesis
Cells; 2022-02-02; 11(3): 524; doi:https://doi.org/10.3390/cells11030524
https://www.mdpi.com/2073-4409/11/3/524/htm
Mayerl S, Alcaide Martin A, Bauer R, Schwaninger M, Heuer H, Ffrench-Constant C


https://pubmed.ncbi.nlm.nih.gov/34848338/
Post-ischemic protein restriction induces sustained neuroprotection, neurological recovery, brain remodeling, and gut microbiota rebalancing.
Brain, Behavior, and Immunity; 2022-02-01; 100(): 134-144; doi: 10.1016/j.bbi.2021.11.016
https://www.sciencedirect.com/science/article/pii/S0889159121006127
de Carvalho TS, Singh V, Yusuf AM, Wang J, Schultz Moreira AR, Sanchez-Mendoza EH, Sardardi M, Nascentes Melo LM, Doeppner TR, Kehrmann J, Scholtysik R, Hitpass L, Gunzer M, Hermann DM


https://pubmed.ncbi.nlm.nih.gov/34389849/
Targeting early stages of cardiotoxicity from anti-PD1 immune checkpoint inhibitor therapy.
European Heart Journal; 2022-01-31; (): ; doi: 10.1093/eurheartj/ehab430
https://academic.oup.com/eurheartj/advance-article-abstract/doi/10.1093/eurheartj/ehab430/6352226?redirectedFrom=fulltext
Michel L, Helfrich I, Hendgen-Cotta UB, Mincu RI, Korste S, Mrotzek SM, Spomer A, Odersky A, Rischpler C, Herrmann K, Umutlu L, Coman C, Ahrends R, Sickmann A, Löffek S, Livingstone E, Ugurel S, Zimmer L, Gunzer M, Schadendorf D, Totzeck M, Rassaf T


https://pubmed.ncbi.nlm.nih.gov/35100966/
Characterisation of cold-induced mitochondrial fission in porcine aortic endothelial cells.
Journal of Molecular Medicine; 2022-01-31; 28(1): ; doi:10.1186/s10020-021-00430-z
https://molmed.biomedcentral.com/articles/10.1186/s10020-021-00430-z
Quiring L, Walter B, Lohaus N, Schwan D, Rech A, Dlugos A, Rauen U


https://pubmed.ncbi.nlm.nih.gov/35038735/
Canonical Thyroid Hormone Receptor ? Action Stimulates Hepatocyte Proliferation in Male Mice
Endocrinology; 2022-01-17; 163(3): ; doi:10.1210/endocr/bqac003
https://academic.oup.com/endo/article/163/3/bqac003/6509895?login=true#330181598
Hönes GS, Kerp H, Hoppe C, Kowalczyk M, Zwanziger D, Baba HA, Führer D, Moeller LC


https://pubmed.ncbi.nlm.nih.gov/34339499/
Thyroid Hormone Transporter Deficiency in Mice Impacts Multiple Stages of GABAergic Interneuron Development.
Cerebral Cortex; 2022-01-10; 32(2): 329-341; doi:10.1093/cercor/bhab211
https://academic.oup.com/cercor/article/32/2/329/6333075?login=false
Mayerl S, Chen J, Salveridou E, Boelen A, Darras VM, Heuer H


https://pubmed.ncbi.nlm.nih.gov/35013174/
Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression.
Nature communications; 2022-01-10; 13(1): 156; doi:https://doi.org/10.1038/s41467-021-27088-9
https://www.nature.com/articles/s41467-021-27088-9
Cheung PF, Yang J, Fang R, Borgers A, Krengel K, Stoffel A, Althoff K, Yip CW, Siu EHL, Ng LWC, Lang KS, Cham LB, Engel DR, Soun C, Cima I, Scheffler B, Striefler JK, Sinn M, Bahra M, Pelzer U, Oettle H, Markus P, Smeets EMM, Aarntzen EHJG, Savvatakis K, Liffers ST, Lueong SS, Neander C, Bazarna A, Zhang X, Paschen A, Crawford HC, Chan AWH, Cheung ST, Siveke JT.


https://pubmed.ncbi.nlm.nih.gov/34105014/
Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice
Basic Research in Cardiology; 2021-06-08; 116(40): ; doi:10.1007/s00395-021-00881-9
https://link.springer.com/article/10.1007/s00395-021-00881-9
Gregorius J, Wang C, Stambouli O, Hussner T, Qi Y, Tertel T, Börger V, Mohamud Yusuf A, Hagemann N, Yin D, Dittrich R, Mouloud Y, Mairinger FD, Magraoui FE, Popa-Wagner A, Kleinschnitz C, Doeppner TR, Gunzer M, Meyer HE, Giebel B, Hermann DM