Fakultät für Biologie

Personenverzeichnis

Die Links zu den Personen führen zum zentralen Personenverzeichnis der UDE, das die Daten aus dem LSF ausliest. Persönliche Informationen können im LSF (nach Login mit der Uni-Kennung) selbst bearbeitet werden.

 

Raum
S03 S02 A48
Telefax

Funktionen

  • Gastprofessor/in, Biologie - Mikrobiologie II

  • Gastwissenschaftler/in, Biologie - Mikrobiologie II

  • Professor/in, Mikrobiologie II

Aktuelle Veranstaltungen

Keine aktuellen Veranstaltungen.

Vergangene Veranstaltungen (max. 10)

Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Fehr, Lorenz; Sewald, Leonard; Huber, Robert; Kaiser, Markus
    Facile Multicomponent Synthesis of Oxazolidinones from Primary Amines and Cesium (Hydrogen)Carbonate
    In: European Journal of Organic Chemistry Jg. 26 (2023) Nr. 27, e202300135
  • Wolf, Christine; Fischer, Hannah; Kühl, Jörn-Sven; Koss, Sarah; Jamra, Rami Abou; Starke, Sven; Schultz, Jurek; Ehl, Stephan; Neumann, Katrin; Schuetz, Catharina; Huber, Robert; Hornung, Veit; Lee-Kirsch, Min Ae
    Hemophagocytic lymphohistiocytosis : Like hyperinflammation due to a de novo mutation in DPP9
    In: The Journal of Allergy and Clinical Immunology Jg. 152 (2023) Nr. 5, S. 1336 - 1344.e5
  • Carvalho, Luís A. R.; Ross, Breyan; Fehr, Lorenz; Bolgi, Oguz; Wöhrle, Svenja; Lum, Kenneth M.; Podlesainski, David; Vieira, Andreia C.; Kiefersauer, Reiner; Félix, Rita; Rodrigues, Tiago; Lucas, Susana D.; Groß, Olaf; Geiss‐Friedlander, Ruth; Cravatt, Benjamin F.; Huber, Robert; Kaiser, Markus; Moreira, Rui
    Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9
    In: Angewandte Chemie International Edition Jg. 61 (2022) Nr. 47, e202210498
  • Bolgi, Oguz; Silva-Garcia, Maria; Ross, Breyan; Pilla, Esther; Kari, Vijayalakshmi; Killisch, Markus; Spitzner, Melanie; Stark, Nadine; Lenz, Christof; Weiss, Konstantin; Donzelli, Laura; Gorrell, Mark D.; Grade, Marian; Riemer, Jan; Urlaub, Henning; Dobbelstein, Matthias; Huber, Robert; Geiss-Friedlander, Ruth
    Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair
    In: EMBO Reports Jg. 23 (2022) Nr. 10, e54136
  • Ross, Breyan; Krapp, Stephan; Geiss-Friedlander, Ruth; Littmann, Walter; Huber, Robert; Kiefersauer, Reiner
    Aerosol-based ligand soaking of reservoir-free protein crystals
    In: Journal of Applied Crystallography Jg. 54 (2021) Nr. 3, S. 895 - 902
  • Lee, Jung-Hoon; Bollschweiler, Daniel; Schäfer, Tillman; Huber, Robert
    Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies
    In: Science Advances Jg. 7 (2021) Nr. 2, S. eabd4413
  • Klatt, Felix; Leitner, Alexander; Kim, Iana V.; Ho-Xuan, Hung; Schneider, Elisabeth V.; Langhammer, Franziska; Weinmann, Robin; Müller, Melanie R.; Huber, Robert; Meister, Gunter; Kuhn, Claus-D.
    A precisely positioned MED12 activation helix stimulates CDK8 kinase activity
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 117 (2020) Nr. 6, S. 2894 - 2905
  • Merdanovic, Melisa; Burston, Steven G.; Schmitz, Anna Laura; Köcher, Steffen; Knapp, Stefan; Clausen, Tim; Kaiser, Markus; Huber, Robert; Ehrmann, Michael
    Activation by substoichiometric inhibition
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 117 (2020) Nr. 3, S. 1414 - 1418
  • Garcia-Guerrero, Maria C.; Garcia-Pardo, Javier; Berenguer, Esther; Fernandez-Alvarez, Roberto; Barfi, Gifty B.; Lyons, Peter J.; Aviles, Francesc X.; Huber, Robert; Lorenzo, Julia; Reverter, David
    Crystal structure and mechanism of human carboxypeptidase O : Insights into its specific activity for acidic residues
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 115 (2018) Nr. 17, S. E3932 - E3939
  • Ross, Breyan; Krapp, Stephan; Augustin, Martin; Kierfersauer, Reiner; Arciniega, Marcelino; Geiss-Friedlander, Ruth; Huber, Robert
    Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 115 (2018) Nr. 7, S. E1437 - E1445
  • Dahms, Sven O.; Arciniega, Marcelino; Steinmetzer, Torsten; Huber, Robert; Than, Manuel E.
    Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 113 (2016) Nr. 40, S. 11196 - 11201
  • Hierold, Judith; Baek, Sohee; Rieger, Rene; Lim, Tae-Guy; Zakpur, Saman; Arciniega, Marcelino; Lee, Kiwon; Huber, Robert; Tietze, Lutz Friedjan
    Design, Synthesis, and Biological Evaluation of Quercetagetin Analogues as JNK1 Inhibitors
    In: Chemistry - A European Journal Jg. 21 (2015) Nr. 47, S. 16887 - 16894
  • Park, Gaeun; Baek, Sohee; Kim, Jong-Eun; Lim, Tae-gyu; Lee, Charles C.; Yang, Hee; Kang, Young-Gyu; Park, Jun Seong; Augustin, Martin; Mrosek, Michael; Lee, Chang Yong; Dong, Zigang; Huber, Robert; Lee, Ki Won
    Flt3 is a target of coumestrol in protecting against UVB-induced skin photoaging
    In: Biochemical Pharmacology Jg. 98 (2015) Nr. 3, S. 473 - 483
  • Beaufort, Nathalie; Scharrer, Eva; Kremmer, Elisabeth; Lux, Vanda; Ehrmann, Michael; Huber, Robert; Houlden, Henry H.; Werring, David John; Haffner, Christof; Dichgans, Martin
    Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β binding protein 1 and facilitates TGF-β signaling
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 111 (2014) Nr. 46, S. 16496 - 16501
  • Arciniega, M.; Beck, P.; Lange, O. F.; Groll, M.; Huber, Robert
    Differential global structural changes in the core particle of yeast and mouse proteasome induced by ligand binding
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 111 (2014) Nr. 26, S. 9479 - 9484
  • Kiefersauer, Reiner; Grandl, Brigitte; Krapp, S.; Huber, Robert
    IR laser-induced protein crystal transformation
    In: Acta Crystallographica Section D: Biological Crystallography Jg. D70 (2014) Nr. 5, S. 1224 - 1232
  • Lesca, E.; Lammens, A.; Huber, Robert; Augustin, M.
    Structural analysis of the human fibroblast growth factor receptor 4 kinase
    In: Journal of Molecular Biology (JMB) Jg. 426 (2014) Nr. 22, S. 3744 - 3756
  • Baek, Sohee; Kang, Nam Joo; Popowicz, Grzegorz M.; Arciniega, Marcelino; Jung, Sung Keun; Byun, Sanguine; Song, Nu Ry; Heo, Yong-Seok; Kim, Bo Yeon; Lee, Hyong Joo; Holak, Tad A.; Augustin, Martin; Bode, Ann M.; Huber, Robert; Dong, Zigang; Lee, Ki Won
    Structural and Functional Analysis of the Natural JNK1 Inhibitor Quercetagetin
    In: Journal of Molecular Biology (JMB) Jg. 425 (2013) Nr. 2, S. 411 - 423
  • Schneider, Elisabeth V.; Böttcher, Jark; Huber, Robert; Maskos, Klaus; Neumann, Lars
    Structure-kinetic relationship study of CDK8/CycC specific compounds
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 110 (2013) Nr. 20, S. 8081 - 8086
  • Huber, Robert
    “How I Chose Research on Proteases or, More Correctly, How it Chose Me”
    In: Angewandte Chemie International Edition Jg. 52 (2013) Nr. 1, S. 68 - 73
  • Weski, Juliane; Meltzer, Michael; Spaan, Lina; Mönig, Timon; Oeljeklaus, Julian; Hauske, Patrick; Vouilleme, Lars; Volkmer, Rudolf; Boisguerin, Prisca; Boyd, Dana; Huber, Robert; Kaiser, Markus; Ehrmann, Michael
    Chemical Biology Approaches Reveal Conserved Features of a C-Terminal Processing PDZ Protease
    In: ChemBioChem Jg. 13 (2012) Nr. 3, S. 402 - 408
  • Tennstaedt, Annette; Pöpsel, Simon; Trübestein, Linda; Hauske, Patrick; Brockmann, Anke; Schmidt, Nina; Irle, Inga; Sacca, Barbara; Niemeyer, Christof M.; Brandt, Roland; Ksiezak-Reding, Hanna; Tirniceriu, Anca Laura; Egensperger, Rupert; Baldi, Alfonso; Dehmelt, Leif; Kaiser, Markus; Huber, Robert; Clausen, Tim; Ehrmann, Michael
    Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates
    In: The Journal of Biological Chemistry (JBC) Jg. 287 (2012) Nr. 25, S. 20931 - 20941
  • Gallastegui, Nerea; Beck, Philipp; Arciniega, Marcelino; Huber, Robert; Hillebrand, Stefan; Groll, Michael
    Hydroxyureas as noncovalent proteasome inhibitors
    In: Angewandte Chemie International Edition Jg. 51 (2012) Nr. 1, S. 247 - 249
  • Baek, Sohee; Kutchukian, Peter S.; Verdine, Gregory L.; Huber, Robert; Holak, Tad A.; Lee, Ki Won; Popowicz, Grzegorz M.
    Structure of the stapled p53 peptide bound to Mdm2
    In: Journal of the American Chemical Society: JACS Jg. 134 (2012) Nr. 1, S. 103 - 106
  • Gallastegui, Nerea; Stein, Martin; Schmidt, Boris; Kloetzel, Peter-Michael; Huber, Robert; Groll, Michael; Gräwert, Melissa Ann
    Elucidation of the α-keto-aldehyde binding mechanism : A lead structure motif for proteasome inhibition
    In: Angewandte Chemie International Edition Jg. 50 (2011) Nr. 2, S. 542 - 544
  • Clausen, Tim; Kaiser, Markus; Huber, Robert; Ehrmann, Michael
    HTRA proteases : regulated proteolysis in protein quality control
    In: Nature Reviews Molecular Cell Biology Jg. 12 (2011) Nr. 3, S. 152 - 162
  • Sitar, Tomasz; Gallinger, Julia; Ducka, Anna M.; Ikonen, Teemu P.; Wohlhoefler, Michael; Schmoller, Kurt M.; Bausch, Andreas R.; Joel, Peteranne; Trybus, Kathleen M.; Noegel, Angelika A.; Schleicher, Michael; Huber, Robert; Holak, Tad A.
    Molecular architecture of the Spire-actin nucleus and its implication for actin filament assembly
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 108 (2011) Nr. 49, S. 19575 - 19580
  • Merdanovic, Melisa; Clausen, Tim; Kaiser, Markus; Huber, Robert; Ehrmann, Michael
    Protein quality control in the bacterial periplasm
    In: Annual Review of Microbiology Jg. 65 (2011) S. 149 - 168
  • Schneider, Elisabeth V.; Böttcher, Jark; Blaesse, Michael; Neumann, Lars; Huber, Robert; Maskos, Klaus
    The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket binder
    In: Journal of Molecular Biology (JMB) Jg. 412 (2011) Nr. 2, S. 251 - 266
  • Clerc, Jérôme; Schellenberg, Barbara; Groll, Michael; Bachmann, André S.; Huber, Robert; Dudler, Robert; Kaiser, Markus
    Convergent synthesis and biological evaluation of syringolin a and derivatives as eukaryotic 20S proteasome inhibitors
    In: European Journal of Organic Chemistry (2010) Nr. 21, S. 3991 - 4003
  • Hasenbein, Sonja; Meltzer, Michael; Hauske, Patrick; Kaiser, Markus; Huber, Robert; Clausen, Tim; Ehrmann, Michael
    Conversion of a regulatory into a degradative protease
    In: Journal of Molecular Biology (JMB) Jg. 397 (2010) Nr. 4, S. 957 - 966
  • Merdanovic, Melisa; Mamant, Nicolette; Meltzer, Michael; Poepsel, Simon; Auckenthaler, Alexandra; Melgaard, Rie; Hauske, Patrick; Nagel-Steger, Luitgard; Clarke, Anthony R.; Kaiser, Markus; Huber, Robert; Ehrmann, Michael
    Determinants of structural and functional plasticity of a widely conserved protease chaperone complex
    In: Nature Structural & Molecular Biology Jg. 17 (2010) Nr. 7, S. 837 - 843
  • Krojer, Tobias; Sawa, Justyna; Huber, Robert; Clausen, Tim
    HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
    In: Nature Structural & Molecular Biology Jg. 17 (2010) Nr. 7, S. 844 - 852
  • Ducka, Anna M.; Joel, Peteranne; Popowicz, Grzegorz M.; Trybus, Kathleen M.; Schleicher, Michael; Noegel, Angelika A.; Huber, Robert; Holak, Tad A.; Sitar, Tomasz
    Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 107 (2010) Nr. 26, S. 11757 - 11762
  • Ottmann, Christian; Rose, Rolf; Huttenlocher, Franziska; Cedzich, Anna; Hauske, Patrick; Kaiser, Markus; Huber, Robert; Schaller, Andreas
    Structural basis for Ca2+-independence and activation by homodimerization of tomato subtilase 3
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 106 (2009) Nr. 40, S. 17223 - 17228
  • Meltzer, Michael; Hasenbein, Sonja; Mamant, Nicolette; Merdanovic, Melisa; Poepsel, Simon; Hauske, Patrick; Kaiser, Markus; Huber, Robert; Krojer, Tobias; Clausen, Tim; Ehrmann, Michael
    Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coli
    In: Research in Microbiology Jg. 160 (2009) Nr. 9, S. 660 - 666
  • Clerc, Jérôme; Groll, Michael; Illich, Damir J.; Bachmann, André S.; Huber, Robert; Schellenberg, Barbara; Dudler, Robert; Kaiser, Markus
    Synthetic and structural studies on Syringolin A and B reveal critical determinants for selectivity and potency of proteasome inhibition
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 106 (2009) Nr. 16, S. 6507 - 6512
  • Clerc, Jérôme; Florea, Bogdan I.; Kraus, Marianne; Groll, Michael; Huber, Robert; Bachmann, André S.; Dudler, Robert; Driessen, Christoph; Overkleeft, Herman S.; Kaiser, Markus
    Syringolin A selectively labels the 20S proteasome in murine EL4 and wildtype and bortezomib adapted leukemic cell lines
    In: ChemBioChem Jg. 10 (2009) Nr. 16, S. 2638 - 2643
  • Groll, Michael; Schellenberg, Barbara; Bachmann, André S.; Archer, Crystal R.; Huber, Robert; Powell, Tracy K.; Lindow, Steven; Kaiser, Markus; Dudler, Robert
    A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism
    In: Nature Jg. 452 (2008) S. 755 - 758
  • Krojer, Tobias; Pangerl, Karen; Kurt, Juliane; Sawa, Justyna; Stingl, Christoph; Mechtler, Karl; Huber, Robert; Ehrmann, Michael; Clausen, Tim
    Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 22 (2008) S. 7702 - 7707
  • Kaiser, Markus; Groll, Michael; Siciliano, Carlo; Assfalg-Machleidt, Irmgard; Weyher, Elisabeth; Kohno, Jun; Milbradt, Alexander G.; Renner, Christian; Huber, Robert; Moroder, Luis
    Binding mode of TMC-95A analogues to eukaryotic 20S proteasome
    In: ChemBioChem Jg. 5 (2004) Nr. 9, S. 1256 - 1266
  • Kim, Jeong-Sun; Groll, Michael; Musiol, Hans-Jürgen; Behrendt, Raymond; Kaiser, Markus; Moroder, Luis; Huber, Robert; Brandstetter, Hans
    Navigation inside a protease: Substrate selection and product exit in the tricorn protease from Thermoplasma acidophilum
    In: Journal of Molecular Biology (JMB) Jg. 324 (2002) Nr. 5, S. 1041 - 1050
  • Kaiser, Markus; Groll, Michael; Renner, Christian; Huber, Robert; Moroder, Luis
    The Core Structure of TMC-95A Is a Promising Lead for Reversible Proteasome Inhibition
    In: Angewandte Chemie International Edition Jg. 41 (2002) Nr. 5, S. 780 - 783
  • Beiträge in Sammelwerken und Tagungsbänden

  • Huber, Robert; Kaiser, Markus; Ehrmann, Michael
    Proteases ☆
    In: Reference Module in Life Sciences 2017
  • Kaiser, Markus; Huber, Robert; Ehrmann, Michael
    Proteolysis
    In: Brenner's Encyclopedia of Genetics: Second Edition / Maloy, Stanley R.; Hughes, Kelly T. 2013, S. 501 - 503
  • Kaiser, Markus; Groll, Michael; Götz, M.; Siciliano, C.; Assfalg-Machleidt, Irmgard; Weyer, E.; Kohno, J.; Milbradt, Alexander; Renner, Christian; Huber, Robert; Moroder, Luis
    Structural determinants for 20S proteasome inhibition by TMC-95A
    In: Peptides 2004 : bridges between disciplines ; proceedings of the Third International and Twenty-Eighth European Peptide Symposium, September 5 - 10, 2004, Prague, Czech Republic / Flegel, Martin (Hrsg.) 2004, S. 657 - 658