Fakultät für Biologie

Personenverzeichnis

Die Links zu den Personen führen zum zentralen Personenverzeichnis der UDE, das die Daten aus dem LSF ausliest. Persönliche Informationen können im LSF (nach Login mit der Uni-Kennung) selbst bearbeitet werden.

 


Funktionen

  • Honorarprofessor/in, Mikrobiologie I

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Die folgenden Publikationen sind in der Online-Universitätsbibliographie der Universität Duisburg-Essen verzeichnet. Weitere Informationen finden Sie gegebenenfalls auch auf den persönlichen Webseiten der Person.

    Artikel in Zeitschriften

  • Polley, Soumitra; Raisch, Tobias; Ghetti, Sabrina; Körner, Marie; Terbeck, Melina; Gräter, Frauke; Raunser, Stefan; Aponte-Santamaría, Camilo; Vetter, Ingrid R.; Musacchio, Andrea
    Structure of the human KMN complex and implications for regulation of its assembly
    In: Nature Structural & Molecular Biology (2024) in press
  • Musacchio, Andrea
    Thirty years of structural changes
    In: Nature Structural & Molecular Biology (2024) in press
  • Cmentowski, Verena; Ciossani, Giuseppe; d'Amico, Ennio; Wohlgemuth, Sabine; Owa, Mikito; Dynlacht, Brian; Musacchio, Andrea
    RZZ‐Spindly and CENP‐E form an integrated platform to recruit dynein to the kinetochore corona
    In: The EMBO Journal Jg. 42 (2023) Nr. 24, e114838
  • Polley, Soumitra; Müschenborn, Helen; Terbeck, Melina; De Antoni, Anna; Vetter, Ingrid R; Dogterom, Marileen; Musacchio, Andrea; Volkov, Vladimir A; Huis in 't Veld, Pim J
    Stable kinetochore-microtubule attachment requires loop-dependent Ndc80-Ndc80 binding
    In: The EMBO Journal Jg. 42 (2023) Nr. 13, e112504
  • Chen, Chu; Piano, Valentina; Alex, Amal; Han, Simon J Y; Huis In 't Veld, Pim J.; Roy, Babhrubahan; Fergle, Daniel; Musacchio, Andrea; Joglekar, Ajit P.; Huis in ’t Veld, Pim J.
    The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint Complex
    In: Nature Communications Jg. 14 (2023) Nr. 1, 1529
  • d'Amico, Ennio A.; Ud Din Ahmad, Misbha; Cmentowski, Verena; Girbig, Mathias; Müller, Franziska; Wohlgemuth, Sabine; Brockmeyer, Andreas; Maffini, Stefano; Janning, Petra; Vetter, Ingrid R.; Carter, Andrew P.; Perrakis, Anastassis; Musacchio, Andrea
    Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin
    In: The Journal of Cell Biology (JCB) Jg. 221 (2022) Nr. 11, e202206131
  • Celestino, Ricardo; Gama, José B; Castro-Rodrigues, Artur F.; Barbosa, Daniel J.; Rocha, Helder; d'Amico, Ennio A.; Musacchio, Andrea; Carvalho, Ana Xavier; Morais-Cabral, João H; Gassmann, Reto; d’Amico, Ennio A.
    JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport
    In: The Journal of Cell Biology (JCB) Jg. 221 (2022) Nr. 8, e202110057
  • Musacchio, Andrea
    On the role of phase separation in the biogenesis of membraneless compartments
    In: The EMBO Journal Jg. 41 (2022) Nr. 5, e109952
  • Martin, Isabel M.; Aponte-Santamaría, Camilo; Schmidt, Lisa; Hedtfeld, Marius; Iusupov, Adel; Musacchio, Andrea; Gräter, Frauke
    Phosphorylation tunes elongation propensity and cohesiveness of INCENP's intrinsically disordered region : Phosphorylation of INCENP disordered region
    In: Journal of Molecular Biology (JMB) Jg. 434 (2022) Nr. 1, 167387
  • Huis in 't Veld, Pim J.; Wohlgemuth, Sabine; Koerner, Carolin; Müller, Franziska; Janning, Petra; Musacchio, Andrea
    Reconstitution and use of highly active human CDK1 : Cyclin-B:CKS1 complexes
    In: Protein Science Jg. 31 (2022) Nr. 2, S. 528 - 537
  • Raisch, Tobias; Ciossani, Giuseppe; d’Amico, Ennio; Cmentowski, Verena; Carmignani, Sara; Maffini, Stefano; Merino, Felipe; Wohlgemuth, Sabine; Vetter, Ingrid R.; Raunser, Stefan; Musacchio, Andrea
    Structure of the RZZ complex and molecular basis of Spindly‐driven corona assembly at human kinetochores
    In: The EMBO Journal Jg. 41 (2022) Nr. 9, e110411
  • Pesenti, Marion E.; Raisch, Tobias; Conti, Duccio; Walstein, Kai; Hoffmann, Ingrid; Vogt, Dorothee; Prumbaum, Daniel; Vetter, Ingrid R.; Raunser, Stefan; Musacchio, Andrea
    Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization
    In: Molecular Cell Jg. 82 (2022) Nr. 11, S. 2113 - 2131.e8
  • Walstein, Kai; Petrovic, Arsen; Pan, Dongqing; Hagemeier, Birte; Vogt, Dorothee; Vetter, Ingrid R.; Musacchio, Andrea
    Assembly principles and stoichiometry of a complete human kinetochore module
    In: Science Advances Jg. 7 (2021) Nr. 27, eabg1037
  • Singh, Priyanka; Pesenti, Marion E.; Maffini, Stefano; Carmignani, Sara; Hedtfeld, Marius; Petrovic, Arsen; Srinivasamani, Anupallavi; Bange, Tanja; Musacchio, Andrea
    BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis
    In: Molecular Cell Jg. 81 (2021) Nr. 1, S. 67 - 87.e9
  • Piano, Valentina; Alex, Amal; Stege, Patricia; Maffini, Stefano; Stoppiello, Gerardo A.; Huis In'T Veld, Pim J.; Vetter, Ingrid R.; Musacchio, Andrea
    CDC20 assists its catalytic incorporation in the mitotic checkpoint complex
    In: Science Jg. 371 (2021) Nr. 6524, S. 67 - 71
  • Mueller, Franziska; Friese, Alexandra; Pathe, Claudio; da Silva, Richard Cardoso; Bravo Rodriguez, Kenny; Musacchio, Andrea; Bange, Tanja
    Overlap of NatA and IAP substrates implicates N-terminal acetylation in protein stabilization
    In: Science Advances Jg. 7 (2021) Nr. 3, S. eabc8590
  • van den Boom, Johannes; Kück, Anja; Kravic, Bojana; Müschenborn, Helen; Giesing, Maike; Pan, Dongqing; Kaschani, Farnusch; Kaiser, Markus; Musacchio, Andrea; Meyer, Hemmo
    Targeted substrate loop insertion by VCP/p97 during PP1 complex disassembly
    In: Nature Structural & Molecular Biology Jg. 28 (2021) Nr. 12, S. 964 - 971
  • Alex, Amal; Piano, Valentina; Polley, Soumitra; Stuiver, Marchel; Voss, Stephanie; Ciossani, Giuseppe; Overlack, Katharina; Voss, Beate; Wohlgemuth, Sabine; Petrovic, Arsen; Wu, Yaowen; Selenko, Philipp; Musacchio, Andrea; Maffini, Stefano
    Electroporated recombinant proteins as tools for in vivo functional complementation, imaging and chemical biology
    In: eLife Jg. 8 (2019) S. e48287
  • Pan, Dongqing; Walstein, Kai; Take, Annika; Bier, David; Kaiser, Nadine; Musacchio, Andrea
    Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing
    In: Nature Communications Jg. 10 (2019) Nr. 1, S. 4046
  • Huis In 't Veld, Pim J.; Volkov, Vladimir A.; Stender, Isabelle D.; Musacchio, Andrea; Dogterom, Marileen
    Molecular determinants of the Ska-Ndc80 interaction and their influence on microtubule tracking and force-coupling
    In: eLife Jg. 8 (2019) S. e49539
  • Sacristan, Carlos; Ahmad, Misbha Ud Din; Keller, Jenny; Fermie, Job; Groenewold, Vincent; Tromer, Eelco; Fish, Alexander; Melero, Roberto; Carazo, José María; Klumperman, Judith; Musacchio, Andrea; Perrakis, Anastassis; Kops, Geert JPL
    Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis
    In: Nature Cell Biology Jg. 20 (2018) S. 800 - 810
  • Pesenti, Marion E; Prumbaum, Daniel; Auckland, Philip; Smith, Charlotte M; Faesen, Alex C; Petrovic, Arsen; Erent, Muriel; Maffini, Stefano; Pentakota, Satyakrishna; Weir, John R; Lin, Yu-Chih; Raunser, Stefan; McAinsh, Andrew D; Musacchio, Andrea
    Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80.
    In: Molecular Cell Jg. 71 (2018) Nr. 6, S. 923 - 939.e10
  • Pan, Dongqing; Brockmeyer, Andreas; Mueller, Franziska; Musacchio, Andrea; Bange, Tanja
    Simplified Protocol for Cross-linking Mass Spectrometry Using the MS-Cleavable Cross-linker DSBU with Efficient Cross-link Identification
    In: Analytical Chemistry Jg. 90 (2018) Nr. 18, S. 10990 - 10999
  • Ciossani, Giuseppe; Overlack, Katharina; Petrovic, Arsen; Huis In 'T Veld, Pim J.; Koerner, Carolin; Wohlgemuth, Sabine; Maffini, Stefano; Musacchio, Andrea
    The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases
    In: The Journal of Biological Chemistry (JBC) Jg. 293 (2018) Nr. 26, S. 10084 - 10101
  • Weith, Matthias; Seiler, Jonas; van den Boom, Johannes; Kracht, Matthias; Hülsmann, Julia; Primorac, Ivana; Del Pino Garcia, Javier; Kaschani, Farnusch; Kaiser, Markus; Musacchio, Andrea; Bollen, Mathieu; Meyer, Hemmo
    Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation
    In: Molecular Cell Jg. 72 (2018) Nr. 4, S. 766 - 777
  • Musacchio, Andrea; Desai, Arshad
    A molecular view of kinetochore assembly and function
    In: Biology Jg. 6 (2017) Nr. 1, S. 5
  • Faesen, Alex C.; Thanasoula, Maria; Maffini, Stefano; Breit, Claudia; Müller, Franziska; Van Gerwen, Suzan; Bange, Tanja; Musacchio, Andrea
    Basis of catalytic assembly of the mitotic checkpoint complex
    In: Nature Jg. 542 (2017) Nr. 7642, S. 498 - 502
  • Overlack, Katharina; Bange, Tanja; Weissmann, Florian; Faesen, Alex C.; Maffini, Stefano; Primorac, Ivana; Müller, Franziska; Peters, Jan-Michael; Musacchio, Andrea
    BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling
    In: Current Biology Jg. 27 (2017) Nr. 19, S. 2915 - 2927.e7
  • Pan, Dongqing; Klare, Kerstin; Petrovic, Arsen; Take, Annika; Walstein, Kai; Singh, Priyanka; Rondelet, Arnaud; Bird, Alexander W; Musacchio, Andrea
    CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading
    In: eLife Jg. 6 (2017) S. e23352
  • Pentakota, Satyakrishna; Zhou, Keda; Smith, Charlotte; Maffini, Stefano; Petrovic, Arsen; Morgan, Garry P.; Weir, John R.; Vetter, Ingrid R.; Musacchio, Andrea; Luger, Karolin
    Decoding the centromeric nucleosome through CENP-N
    In: eLife Jg. 6 (2017) S. e33442
  • Mosalaganti, Shyamal; Keller, Jenny; Altenfeld, Anika; Winzker, Michael; Rombaut, Pascaline; Saur, Michael; Petrovic, Arsen; Wehenke, Annemarie; Wohlgemuth, Sabine; Müller, Franziska; Maffini, Stefano; Bange, Tanja; Herzog, Franz; Waldmann, Herbert; Raunser, Stefan; Musacchio, Andrea
    Structure of the RZZ complex and molecular basis of its interaction with Spindly
    In: The Journal of Cell Biology (JCB) Jg. 216 (2017) Nr. 4, S. 961 - 981
  • Vader, Gerben; Musacchio, Andrea
    The greatest kinetochore show on earth
    In: EMBO Reports Jg. 18 (2017) Nr. 9, S. 1473 - 1475
  • Weir, John R.; Faesen, Alex C.; Klare, Kerstin; Petrovic, Arsen; Basilico, Federica; Fischböck, Josef; Pentakota, Satyakrishna; Keller, Jenny; Pesenti, Marion E.; Pan, Dongqing; Vogt, Doro; Wohlgemuth, Sabine; Herzog, Franz; Musacchio, Andrea
    Insights from biochemical reconstitution into the architecture of human kinetochores
    In: Nature Jg. 537 (2016) Nr. 7619, S. 249 - 253
  • Liu, Yahui; Petrovic, Arsen; Rombaut, Pascaline; Mosalaganti, Shyamal; Keller, Jenny; Raunser, Stefan; Herzog, Franz; Musacchio, Andrea
    Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogaster
    In: Open Biology Jg. 6 (2016) Nr. 2, 150236
  • Borisy, Gary; Musacchio, Andrea; Janke, Carsten; Howard, Jonathon; Heald, Rebecca; Nogales, Eva
    Microtubules : 50 years on from the discovery of tubulin
    In: Nature Reviews Molecular Cell Biology Jg. 17 (2016) Nr. 5, S. 322 - 328
  • Huisin’T Veld, Pim J.; Jeganathan, Sadasivam; Petrovic, Arsen; Singh, Priyanka; John, Juliane; Krenn, Veronica; Weissmann, Florian; Bange, Tanja; Musacchio, Andrea
    Molecular basis of outer kinetochore assembly on CENP-T
    In: eLife Jg. 5 (2016) S. e21007
  • Friese, Alexandra; Musacchio, Andrea; Herzog, Franz; Raunser, Stefan; Petrovic, Arsen; Prumbaum, Daniel; Fischböck, Josef; Huis in ‘t Veld,, Pim J.; Faesen, Alex C.
    Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin
    In: Nature Communications Jg. 7 (2016) S. 11407
  • Pesenti, Marion E.; Weir, John R.; Musacchio, Andrea
    Progress in the structural and functional characterization of kinetochores
    In: Current Opinion in Structural Biology Jg. 37 (2016) S. 152 - 163
  • O'Connor, Aisling; Maffini, Stefano; Rainey, Michael D.; Kaczmarczyk, Agnieszka; Gaboriau, David; Musacchio, Andrea; Santocanale, Corrado
    Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint
    In: Biology Open: BiO Jg. 5 (2016) Nr. 1, S. 11 - 19
  • Petrovic, Arsen; Keller, Jenny; Liu, Yahui; Overlack, Katharina; John, Juliane; Dimitrova, Yoana N.; Jenni, Simon; van Gerwen, Suzan; Stege, Patricia; Wohlgemuth, Sabine; Rombaut, Pascaline; Herzog, Franz; Harrison, Stephen C.; Vetter, Ingrid R.; Musacchio, Andrea
    Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores
    In: Cell Jg. 167 (2016) Nr. 4, S. 1028 - 1040.e15
  • Overlack, Katharina; Primorac, Ivana; Vleugel, Mathijs; Krenn, Veronica; Maffini, Stefano; Hoffmann, Ingrid; Kops, Geert J. P. L.; Musacchio, Andrea
    A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint
    In: eLife Jg. 4 (2015) S. e05269
  • Klare, Kerstin; Weir, John R.; Basilico, Federica; Zimniak, Tomasz; Massimiliano, Lucia; Ludwigs, Nina; Herzog, Franz; Musacchio, Andrea
    CENP-C is a blueprint for constitutive centromere-associated network assembly within human kinetochores
    In: The Journal of Cell Biology (JCB) Jg. 210 (2015) Nr. 1, S. 11 - 22
  • Musacchio, Andrea
    Closing the Mad2 cycle : chromosome separation is regulated by a cycle that involves a protein undergoing an unusual topological conversion
    In: eLife Jg. 4 (2015) S. e08283
  • Altenfeld, Anika; Wohlgemuth, Sabine; Wehenkel, Annemarie; Vetter, Ingrid R.; Musacchio, Andrea
    Complex assembly, crystallization and preliminary x-ray crystallographic analysis of the human Rod-Zwilch-ZW10 (RZZ) complex
    In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications Jg. 71 (2015) Nr. 4, S. 438 - 442
  • Meyer, Rebecca; Faesen, Alex; Vogel, Katrin; Jeganathan, Sadasivam; Musacchio, Andrea; Niemeyer, Christof M.
    DNA-directed assembly of capture tools for constitutional studies of large protein complexes
    In: Small Jg. 11 (2015) Nr. 22, S. 2669 - 2674
  • Tachiwana, Hiroaki; Müller, Sebastian; Blümer, Julia; Klare, Kerstin; Musacchio, Andrea; Almouzni, Geneviève
    HJURP involvement in De Novo CenH3CENP-A and CENP-C recruitment
    In: Cell Reports Jg. 11 (2015) Nr. 1, S. 22 - 32
  • Breit, Claudia; Bange, Tanja; Petrović, Arsen N.; Weir, John R.; Müller, Franziska; Vogt, Doro; Musacchio, Andrea
    Role of intrinsic and extrinsic factors in the regulation of the mitotic checkpoint kinase Bub1
    In: PLoS ONE Jg. 10 (2015) Nr. 12, S. 0144673
  • Faesen, Alex C.; Musacchio, Andrea
    The (phospho) needle in the (MELT) haystack
    In: Molecular Cell Jg. 57 (2015) Nr. 5, S. 765 - 766
  • Krenn, Veronica; Musacchio, Andrea
    The Aurora B kinase in chromosome bi-orientation and spindle checkpoint signaling
    In: Frontiers in Oncology Jg. 5 (2015) S. 225
  • Musacchio, Andrea
    The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics
    In: Current Biology Jg. 25 (2015) Nr. 20, S. R1002 - R1018
  • Vader, Gerben; Musacchio, Andrea
    HORMA domains at the heart of meiotic chromosome dynamics
    In: Developmental Cell Jg. 31 (2014) Nr. 4, S. 389 - 391
  • Eiteneuer, Annika; Seiler, Jonas; Weith, Matthias; Beullens, Monique; Lesage, Bart; Krenn, Veronica; Musacchio, Andrea; Bollen, Mathieu; Meyer, Hemmo
    Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1
    In: The EMBO Journal Jg. 33 (2014) Nr. 22, S. 2704 - 2720
  • Krenn, Veronica; Overlack, Katharina; Primorac, Ivana; Van Gerwen, Suzan; Musacchio, Andrea
    KI motifs of human Knl1 enhance assembly of comprehensive spindle checkpoint complexes around MELT repeats
    In: Current Biology Jg. 24 (2014) Nr. 1, S. 29 - 39
  • Petrovic, Arsen; Mosalaganti, Shyamal; Keller, Jenny; Mattiuzzo, Marta; Overlack, Katharina; Krenn, Veronica; De Antoni, Anna; Wohlgemuth, Sabine; Cecatiello, Valentina; Pasqualato, Sebastiano; Raunser, Stefan; Musacchio, Andrea
    Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization
    In: Molecular Cell Jg. 53 (2014) Nr. 4, S. 591 - 605
  • Basilico, Federica; Maffini, Stefano; Weir, John R.; Prumbaum, Daniel; Rojas, Ana M.; Zimniak, Tomasz; De Antoni, Anna; Jeganathan, Sadasivam; Voss, Beate; Van Gerwen, Suzan; Krenn, Veronica; Massimiliano, Lucia; Valencia, Alfonso; Vetter, Ingrid R.; Herzog, Franz; Raunser, Stefan; Pasqualato, Sebastiano; Musacchio, Andrea
    The pseudo GTPase CENP-M drives human kinetochore assembly
    In: eLife Jg. 3 (2014) S. e02978
  • Overlack, Katharina; Krenn, Veronica; Musacchio, Andrea
    When Mad met Bub
    In: EMBO Reports Jg. 15 (2014) Nr. 4, S. 326 - 328
  • Primorac, Ivana; Weir, John R.; Chiroli, Elena; Gross, Fridolin; Hoffmann, Ingrid; Van Gerwen, Suzan; Ciliberto, Andrea; Musacchio, Andrea
    Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling
    In: eLife Jg. 2 (2013) S. e01030
  • Earnshaw, William C.; Allshire, Robin C.; Black, Ben E.; Bloom, Kerry; Brinkley, Bill R.; Brown, William; Cheeseman, Iain M.; Choo, Kong H. A.; Copenhaver, Gregory P.; DeLuca, Jennifer G.; Desai, Arshad; Diekmann, Stephan; Erhardt, Sylvia; Fitzgerald-Hayes, Molly; Foltz, Daniel; Fukagawa, Tatsuo; Gassmann, Reto; Gerlich, Daniel W.; Glover, David M.; Gorbsky, Gary J.; Harrison, Stephen C.; Heun, Patrick; Hirota, Toru; Jansen, Lars E. T.; Karpen, Gary; Kops, Geert J. P. L.; Lampson, Michael A.; Lens, Susanne M.; Losada, Ana; Luger, Karolin; Maiato, Helder; Maddox, Paul S.; Margolis, Robert L.; Masumoto, Hiroshi; McAinsh, Andrew D.; Mellone, Barbara G.; Meraldi, Patrick; Musacchio, Andrea; Oegema, Karen; O'Neill, Rachel J.; Salmon, Edward D.; Scott, Kristin C.; Straight, Aaron F.; Stukenberg, Peter T.; Sullivan, Beth A.; Sullivan, Kevin F.; Sunkel, Claudio E.; Swedlow, Jason R.; Walczak, Claire E.; Warburton, Peter E.; Westermann, Stefan; Willard, Huntington F.; Wordeman, Linda; Yanagida, Mitsuhiro; Yen, Tim J.; Yoda, Kinya; Cleveland, Don W.
    Esperanto for histones : CENP-A, not CenH3, is the centromeric histone H3 variant
    In: Chromosome Research Jg. 21 (2013) Nr. 2, S. 101 - 106
  • Hagemann, S.; Wohlschläger, Jeremias; Bertram, S.; Levkau, Bodo; Musacchio, Andrea; Conway, E. M.; Möllmann, D.; Kneiseler, G.; Pless-Petig, G.; Lorenz, Kristina; Sitek, B.; Baba, Hideo Andreas
    Loss of survivin influences liver regeneration and is associated with impaired aurora B function
    In: Cell Death and Differentiation Jg. 20 (2013) Nr. 6, S. 834 - 844
  • Primorac, Ivana; Musacchio, Andrea
    Panta rhei : the APC/C at steady state
    In: The Journal of Cell Biology (JCB) Jg. 201 (2013) Nr. 2, S. 177 - 189
  • Musacchio, Andrea; Ciliberto, Andrea
    The spindle-assembly checkpoint and the beauty of self-destruction : Erratum
    In: Nature Structural & Molecular Biology Jg. 20 (2013) Nr. 2, S. 244
  • De Antoni, Anna; Maffini, Stefano; Knapp, Stefan; Musacchio, Andrea; Santaguida, Stefano
    A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B
    In: The Journal of Cell Biology (JCB) Jg. 199 (2012) Nr. 2, S. 269 - 284
  • Elkins, Jonathan M.; Santaguida, Stefano; Musacchio, Andrea; Knapp, Stefan
    Crystal structure of human Aurora B in complex with INCENP and VX-680
    In: Journal of Medicinal Chemistry Jg. 55 (2012) Nr. 17, S. 7841 - 7848
  • Musacchio, Andrea
    Q & A : Andrea Musacchio
    In: Current Biology Jg. 22 (2012) Nr. 14, S. R552 - R554
  • Mariani, Luca; Chiroli, Elena; Nezi, Luigi; Müller, Heiko; Piatti, Simonetta; Musacchio, Andrea; Ciliberto, Andrea
    Role of the Mad2 dimerization interface in the spindle assembly checkpoint independent of kinetochores
    In: Current Biology Jg. 22 (2012) Nr. 20, S. 1900 - 1908
  • Kwiatkowski, Nicholas; Deng, Xianming; Wang, Jinhua; Tan, Li; Villa, Fabrizio; Santaguida, Stefano; Huang, Hsiao-Chun; Mitchison, Tim; Musacchio, Andrea; Gray, Nathanael
    Selective aurora kinase inhibitors identified using a taxol-induced checkpoint sensitivity screen
    In: ACS Chemical Biology Jg. 7 (2012) Nr. 1, S. 185 - 196
  • Krenn, Veronica; Wehenkel, Annemarie; Li, Xiaozheng; Santaguida, Stefano; Musacchio, Andrea
    Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction
    In: The Journal of Cell Biology (JCB) Jg. 196 (2012) Nr. 4, S. 451 - 467
  • DeLuca, Jennifer G.; Musacchio, Andrea
    Structural organization of the kinetochore-microtubule interface
    In: Current Opinion in Cell Biology Jg. 24 (2012) Nr. 1, S. 48 - 56
  • Musacchio, Andrea; Ciliberto, Andrea
    The spindle-assembly checkpoint and the beauty of self-destruction
    In: Nature Structural & Molecular Biology Jg. 19 (2012) Nr. 11, S. 1059 - 1061
  • Balzano, Deborah; Santaguida, Stefano; Musacchio, Andrea; Villa, Fabrizio
    A general framework for inhibitor resistance in protein kinases
    In: Chemistry and Biology Jg. 18 (2011) Nr. 8, S. 966 - 975
  • Balzano, Deborah; Santaguida, Stefano; Musacchio, Andrea; Villa, Fabrizio
    A general framework for inhibitor resistance in protein kinases : Erratum
    In: Chemistry and Biology Jg. 18 (2011) Nr. 10, S. 1341
  • Mattiuzzo, Marta; Vargiu, Giulia; Totta, Pierangela; Fiore, Mario; Ciferri, Claudio; Musacchio, Andrea; Degrassi, Francesca
    Abnormal kinetochore-generated pulling forces from expressing a n-terminally modified Hec1
    In: PLoS ONE Jg. 6 (2011) Nr. 1, S. e16307
  • Screpanti, Emanuela; De Antoni, Anna; Alushin, Gregory M.; Petrovic, Arsen; Melis, Tiziana; Nogales, Eva; Musacchio, Andrea
    Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore
    In: Current biology Jg. 21 (2011) Nr. 5, S. 391 - 398
  • Santaguida, Stefano; Vernieri, Claudio; Villa, Fabrizio; Ciliberto, Andrea; Musacchio, Andrea
    Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction
    In: The EMBO Journal Jg. 30 (2011) Nr. 8, S. 1508 - 1519
  • Varetti, Gianluca; Guida, Claudia; Santaguida, Stefano; Chiroli, Elena; Musacchio, Andrea
    Homeostatic control of mitotic arrest
    In: Molecular cell Jg. 44 (2011) Nr. 5, S. 710 - 720
  • Perrakis, Anastassis; Musacchio, Andrea; Cusack, Stephen; Petosa, Carlo
    Investigating a macromolecular complex : the toolkit of methods
    In: Journal of Structural Biology Jg. 175 (2011) Nr. 2, S. 106 - 112
  • Alexander, Jes; Lim, Daniel; Joughin, Brian A.; Hegemann, Björn; Hutchins, James R. A.; Ehrenberger, Tobias; Ivins, Frank; Sessa, Fabio; Hudecz, Otto; Nigg, Erich A.; Fry, Andrew M.; Musacchio, Andrea; Stukenberg, P. Todd; Mechtler, Karl; Peters, Jan-Michael; Smerdon, Stephen J.; Yaffe, Michael B.
    Spatial exclusivity combined with positive and negative selection of phosphorylation motifs Is the basis for context-dependent mitotic signaling
    In: Science signaling Jg. 4 (2011) Nr. 179, 1-15, art. no. ra42
  • Musacchio, Andrea
    Spindle assembly checkpoint : the third decade
    In: Philosophical transactions of the Royal Society : series B, biological sciences Jg. 366 (2011) Nr. 1584, S. 3595 - 3604
  • Maspero, Elena; Mari, Sara; Valentini, Eleonora; Musacchio, Andrea; Fish, Alexander; Pasqualato, Sebastiano; Polo, Simona
    Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation
    In: EMBO Reports Jg. 12 (2011) Nr. 4, S. 342 - 349
  • Maure, Jean-François; Komoto, Shinya; Oku, Yusuke; Mino, Akihisa; Pasqualato, Sebastiano; Natsume, Kayo; Clayton, Lesley; Musacchio, Andrea; Tanaka, Tomoyuki U.
    The Ndc80 loop region facilitates formation of kinetochore attachment to the dynamic microtubule plus end
    In: Current biology Jg. 21 (2011) Nr. 3, S. 207 - 213
  • Musacchio, Andrea
    Travel notes from the equatorial circle
    In: Cell Jg. 146 (2011) Nr. 4, S. 499 - 501
  • Musacchio, Andrea
    Cell cycle : deconstructing tension
    In: Current biology Jg. 20 (2010) Nr. 15, S. R634 - R637
  • Santaguida, Stefano; Tighe, Anthony; D'Alise, Anna M.; Taylor, Stephen S.; Musacchio, Andrea
    Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine
    In: The Journal of Cell Biology (JCB) Jg. 190 (2010) Nr. 1, S. 73 - 87
  • Civril, Filiz; Wehenkel, Annemarie; Giorgi, Federico M.; Santaguida, Stefano; Di Fonzo, Andrea; Grigorean, Gabriela; Ciccarelli, Francesca D.; Musacchio, Andrea
    Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery
    In: Structure Jg. 18 (2010) Nr. 5, S. 616 - 626
  • Hewitt, Laura; Tighe, Anthony; Santaguida, Stefano; White, Anne M.; Jones, Clifford D.; Musacchio, Andrea; Green, Stephen; Taylor, Stephen S.
    Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex
    In: The Journal of Cell Biology (JCB) Jg. 190 (2010) Nr. 1, S. 25 - 34
  • Petrovic, Arsen; Pasqualato, Sebastiano; Dube, Prakash; Krenn, Veronica; Santaguida, Stefano; Cittaro, Davide; Monzani, Silvia; Massimiliano, Lucia; Keller, Jenny; Tarricone, Aldo; Maiolica, Alessio; Stark, Holger; Musacchio, Andrea
    The MIS12 complex is a protein interaction hub for outer kinetochore assembly
    In: The Journal of Cell Biology (JCB) Jg. 190 (2010) Nr. 5, S. 835 - 852
  • Villa, Fabrizio; Capasso, Paola; Tortorici, Marcello; Forneris, Federico; De Marco, Ario; Mattevi, Andrea; Musacchio, Andrea
    Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 106 (2009) Nr. 48, S. 20204 - 20209
  • Nezi, Luigi; Musacchio, Andrea
    Sister chromatid tension and the spindle assembly checkpoint
    In: Current Opinion in Cell Biology Jg. 21 (2009) Nr. 6, S. 785 - 795
  • Amabile, Giovanni; D'Alise, Anna M.; Iovino, Mariangela; Jones, Philip; Santaguida, Stefano; Musacchio, Andrea; Taylor, Stephen; Cortese, Riccardo
    The Aurora B kinase activity is required for the maintenance of the differentiated state of murine myoblasts
    In: Cell death and differentiation Jg. 16 (2009) Nr. 2, S. 321 - 330
  • Santaguida, Stefano; Musacchio, Andrea
    The life and miracles of kinetochores
    In: The EMBO Journal Jg. 28 (2009) Nr. 17, S. 2511 - 2531
  • Andersen, Carsten B.; Wan, Yongqin; Chang, Jae W.; Riggs, Blake; Lee, Christian; Liu, Yi; Sessa, Fabio; Villa, Fabrizio; Kwiatkowski, Nicholas; Suzuki, Melissa; Nallan, Laxman; Heald, Rebecca; Musacchio, Andrea; Gray, Nathanael S.
    Discovery of selective aminothiazole aurora kinase inhibitors
    In: ACS Chemical Biology Jg. 3 (2008) Nr. 3, S. 180 - 192
  • Ciferri, Claudio; Pasqualato, Sebastiano; Screpanti, Emanuela; Varetti, Gianluca; Santaguida, Stefano; Dos Reis, Gabriel; Maiolica, Alessio; Polka, Jessica; De Luca, Jennifer G.; De Wulf, Peter; Salek, Mogjiborahman; Rappsilber, Juri; Moores, Carolyn A.; Salmon, Edward D.; Musacchio, Andrea
    Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex
    In: Cell Jg. 133 (2008) Nr. 3, S. 427 - 439
  • Civril, Filiz; Musacchio, Andrea
    Spindly attachments
    In: Genes and development Jg. 22 (2008) Nr. 17, S. 2302 - 2307
  • Varetti, Gianluca; Musacchio, Andrea
    The spindle assembly checkpoint
    In: Current biology Jg. 18 (2008) Nr. 14, S. R591 - R595
  • Varetti, Gianluca; Musacchio, Andrea
    The spindle assembly checkpoint : correction
    In: Current biology Jg. 18 (2008) Nr. 18, S. 1444
  • Mapelli, Marina; Musacchio, Andrea
    MAD contortions : conformational dimerization boosts spindle checkpoint signaling
    In: Current opinion in structural biology Jg. 17 (2007) Nr. 6, S. 716 - 725
  • Plyte, Simon; Musacchio, Andrea
    PLK1 inhibitors : setting the mitotic death trap
    In: Current biology Jg. 17 (2007) Nr. 8, S. R280 - R283
  • Mapelli, Marina; Massimiliano, Lucia; Santaguida, Stefano; Musacchio, Andrea
    The Mad2 conformational dimer : structure and implications for the spindle assembly checkpoint
    In: Cell Jg. 131 (2007) Nr. 4, S. 730 - 743
  • Ciferri, Claudio; Musacchio, Andrea; Petrovic, Arsen
    The Ndc80 complex : hub of kinetochore activity
    In: FEBS Letters Jg. 581 (2007) Nr. 15, S. 2862 - 2869
  • Musacchio, Andrea; Salmon, Edward D.
    The spindle-assembly checkpoint in space and time
    In: Nature reviews : molecular cell biology Jg. 8 (2007) Nr. 5, S. 379 - 393
  • Derewenda, Urszula; Tarricone, Cataldo; Choi, Won C.; Cooper, David R.; Lukasik, Steve; Perrina, Franco; Tripathy, Ashutosh; Kim, Myung H.; Cafiso, David S.; Musacchio, Andrea; Derewenda, Zygmunt S.
    The structure of the coiled-coil domain of Ndel1 and the basis of its interaction with Lis1, the causal protein of Miller-Dieker lissencephaly
    In: Structure Jg. 15 (2007) Nr. 11, S. 1467 - 1481
  • Nezi, Luigi; Rancati, Giulia; De Antoni, Anna; Pasqualato, Sebastiano; Piatti, Simonetta; Musacchio, Andrea
    Accumulation of Mad2-Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae
    In: The Journal of Cell Biology (JCB) Jg. 174 (2006) Nr. 1, S. 39 - 51
  • Penengo, Lorenza; Mapelli, Marina; Murachelli, Andrea G.; Confalonieri, Stefano; Magri, Laura; Musacchio, Andrea; Di Fiore, Pier P.; Polo, Simona; Schneider, Thomas R.
    Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin
    In: Cell Jg. 124 (2006) Nr. 6, S. 1183 - 1195
  • Mapelli, Marina; Filipp, Fabian V.; Rancati, Giulia; Massimiliano, Lucia; Nezi, Luigi; Stier, Gunter; Hagan, Robert S.; Confalonieri, Stefano; Piatti, Simonetta; Sattler, Michael; Musacchio, Andrea
    Determinants of conformational dimerization of Mad2 and its inhibition by p31comet
    In: The EMBO Journal Jg. 25 (2006) Nr. 6, S. 1273 - 1284
  • Vink, Martin; Simonetta, Marco; Transidico, Pietro; Ferrari, Karin; Mapelli, Marina; De Antoni, Anna; Massimiliano, Lucia; Ciliberto, Andrea; Faretta, Mario; Salmon, Edward D.; Musacchio, Andrea
    In vitro FRAP identifies the minimal requirements for Mad2 kinetochore dynamics
    In: Current biology Jg. 16 (2006) Nr. 8, S. 755 - 766
  • DeLuca, Jennifer G.; Gall, Walter E.; Ciferri, Claudio; Cimini, Daniela; Musacchio, Andrea; Salmon, Edward D.
    Kinetochore microtubule dynamics and attachment stability are regulated by Hec1
    In: Cell Jg. 127 (2006) Nr. 5, S. 969 - 982
  • Ciferri, Claudio; De Luca, Jennifer; Monzani, Silvia; Ferrari, Karin J.; Ristic, Dejan; Wyman, Claire; Stark, Holger; Kilmartin, John; Salmon, Edward D.; Musacchio, Andrea
    Architecture of the human Ndc80-Hec1 complex, a critical constituent of the outer kinetochore
    In: The Journal of Biological Chemistry (JBC) Jg. 280 (2005) Nr. 32, S. 29088 - 29095
  • De Antoni, Anna; Sala, Valeria; Musacchio, Andrea
    Explaining the oligomerization properties of the spindle assembly checkpoint protein Mad2
    In: Philosophical transactions of the Royal Society : series B, biological sciences Jg. 360 (2005) Nr. 1455, S. 637 - 648
  • Sessa, Fabio; Mapelli, Marina; Ciferri, Claudio; Tarricone, Cataldo; Areces, Liliana B.; Schneider, Thomas R.; Stukenberg, P. Todd; Musacchio, Andrea
    Mechanism of Aurora B activation by INCENP and inhibition by Hesperadin
    In: Molecular cell Jg. 18 (2005) Nr. 3, S. 379 - 391
  • De Antoni, Anna; Pearson, Chad G.; Cimini, Daniela; Canman, Julie C.; Sala, Valeria; Nezi, Luigi; Mapelli, Marina; Sironi, Lucia; Faretta, Mario; Salmon, Edward D.; Musacchio, Andrea
    The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint
    In: Current biology Jg. 15 (2005) Nr. 3, S. 214 - 225
  • Mapelli, Marina; Musacchio, Andrea
    The structural perspective on CDK5
    In: Neurosignals Jg. 12 (2003) Nr. 4-5, S. 164 - 172
  • Sironi, Lucia; Mapelli, Marina; Knapp, Stefan; De Antoni, Anna; Jeang, Kuan‐Teh; Musacchio, Andrea
    Crystal structure of the tetrameric Mad1-Mad2 core complex : implications of 'safety belt' binding mechanism for the spindle checkpoint
    In: The EMBO Journal Jg. 21 (2002) Nr. 10, S. 2496 - 2506
  • Musacchio, Andrea; Hardwick, Kevin G.
    The spindle checkpoint : structural insights into dynamic signalling
    In: Nature reviews : molecular cell biology Jg. 3 (2002) Nr. 10, S. 731 - 741
  • Fraschini, Roberta; Beretta, Alessia; Sironi, Lucia; Musacchio, Andrea; Lucchini, Giovanna; Piatti, Simonetta
    Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores
    In: The EMBO Journal Jg. 20 (2001) Nr. 23, S. 6648 - 6659
  • Sironi, Lucia; Melixetian, Marina; Faretta, Mario; Prosperini, Elena; Helin, Kristian; Musacchio, Andrea
    Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for spindle checkpoint
    In: The EMBO Journal Jg. 20 (2001) Nr. 22, S. 6371 - 6382
  • Tarricone, Cataldo; Dhavan, Rani; Peng, Junmin; Areces, Liliana B.; Tsai, Li-Huei; Musacchio, Andrea
    Structure and regulation of the CDK5-p25nck5a complex
    In: Molecular cell Jg. 8 (2001) Nr. 3, S. 657 - 669
  • Orrico, Alfredo; Galli, Lucia; Falciani, Michela; Bracci, Martina; Cavaliere, Maria L.; Rinaldi, Maria M.; Musacchio, Andrea; Sorrentino, Vincenzo
    A mutation in the pleckstrin homology (PH) domain of the FGD1 gene in an Italian family with faciogenital dysplasia (Aarskog-Scott syndrome)
    In: FEBS Letters Jg. 478 (2000) Nr. 3, S. 216 - 220
  • Kang, Hyun; Freund, Christian; Duke‐Cohan, Jonathan S.; Musacchio, Andrea; Wagner, Gerhard; Rudd, Christopher E.
    SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55
    In: The EMBO Journal Jg. 19 (2000) Nr. 12, S. 2889 - 2899
  • Mongioví, Adriana M.; Romano, Pascale R.; Panni, Simona; Mendoza, Manuel; Wong, William T.; Musacchio, Andrea; Cesareni, Gianni; Di Fiore, Pier P.
    A novel peptide-SH3 interaction
    In: The EMBO Journal Jg. 18 (1999) Nr. 19, S. 5300 - 5309
  • Musacchio, Andrea; Smith, Corinne J.; Roseman, Alan M.; Harrison, Stephen C.; Kirchhausen, Tomas; Pearse, Barbara M. F.
    Functional organization of clathrin in coats : combining electron cryomicroscopy and x-ray crystallography
    In: Molecular cell Jg. 3 (1999) Nr. 6, S. 761 - 770
  • Ter Haar, Ernst; Musacchio, Andrea; Harrison, Stephen C.; Kirchhausen, Tomas
    Atomic structure of clathrin : a β propeller terminal domain joins an α zigzag linker
    In: Cell Jg. 95 (1998) Nr. 4, S. 563 - 573
  • Musacchio, Andrea; Cantley, Lewis C.; Harrison, Stephen C.
    Crystal structure of the breakpoint cluster region homology domain from phosphoinositide 3-kinase p85 alpha subunit
    In: Proceedings of the National Academy of Sciences of the United States of America (PNAS) Jg. 93 (1996) Nr. 25, S. 14373 - 14378
  • Saraste, Matti; Musacchio, Andrea
    Backwards and forwards binding
    In: Nature structural biology Jg. 1 (1994) Nr. 12, S. 835 - 837
  • Musacchio, Andrea; Wilmanns, Matthias; Saraste, Matti
    Structure and function of the SH3 domain
    In: Progress in biophysics and molecular biology Jg. 61 (1994) Nr. 3, S. 283 - 297
  • Noble, Martin E. M.; Musacchio, Andrea; Saraste, Matti; Courtneidge, Sara A.; Wierenga, Rik K.
    Crystal structure of the SH3 domain in human Fyn : comparison of the three-dimensional structures of SH3 domains in tyrosine kinases and spectrin
    In: The EMBO Journal Jg. 12 (1993) Nr. 7, S. 2617 - 2624
  • Van der Oost, John; Musacchio, Andrea; Pauptit, Richard A.; Ceska, Thomas A.; Wierenga, Rik K.; Saraste, Matti
    Crystallization and preliminary x-ray analysis of the periplasmic fragment of CyoA-a subunit of the Escherichia coli cytochrome o complex
    In: Journal of Molecular Biology (JMB) Jg. 229 (1993) Nr. 3, S. 794 - 796
  • Musacchio, Andrea; Gibson, Toby; Rice, Peter; Thompson, Julie; Saraste, Matti
    The PH domain : a common piece in the structural pathcwork of signalling proteins
    In: Trends in biochemical sciences Jg. 18 (1993) Nr. 9, S. 343 - 348
  • Musacchio, Andrea; Noble, Martin; Pauptit, Richard; Wierenga, Rik; Saraste, Matti
    Crystal structure of a Src-homology 3 (SH3) domain
    In: Nature Jg. 359 (1992) Nr. 6398, S. 851 - 855
  • Aufsätze

  • Pleuger, Richard; Cozma, Christian; Hohoff, Simone; Denkhaus, Christian; Dudziak, Alexander; Kaschani, Farnusch; Musacchio, Andrea; Vetter, Ingrid R.; Westermann, Stefan
    Ipl1-controlled attachment maturation regulates Mps1 association with its kinetochore receptor
    (2023) 43 Seiten
  • d'Amico, Ennio; Ud Din Ahmad, Misbha; Cmentowski, Verena; Girbig, Mathias; Mueller, Franziska; Wohlgemuth, Sabine; Brockmeyer, Andreas; Maffini, Stefano; Janning, Petra; Vetter, Ingrid R.; Carter, Andrew P.; Perrakis, Anastassis; Musacchio, Andrea
    Conformational transitions of the mitotic adaptor Spindly underlie its interaction with Dynein and Dynactin
    (2022)
  • Vorworte / Nachworte

  • Musacchio, Andrea; Helin, Kristian
    Cell cycle, differentiation and disease : editorial overview
    In: Current Opinion in Cell Biology Jg. 25 (2013) Nr. 6, S. 673 - 675