Welcome to ZMB

Welcome to ZMB

The Center of Medical Biotechnology (ZMB) is an interdisciplinary scientific center of the University of Duisburg-Essen, integrating medical research at the University Hospital and natural sciences at the Campus.

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RC OHR Seminar Series

The RC OHR Seminar Series explores health in alignment with the One Health concept, linking ecosystem and human health.

First Wednesday of every month, 4:00-5:00 PM CET, online via Zoom

03.06.2026
Prof. Caspar Schwierdrzik, RUB.

01.07.2026
Prof. Helen Blank, RUB.

05.08.2026
Prof. Bernd Sures, UDE.

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A lecture series of UDE’s DFG networks in the field of Biomedical Sciences Sex and Gender in the Life Sciences

Perspectives on how research in the life sciences can utilize the analytical potential of the gender dimension and open up new directions.

June 11, 2026 - 4pm online lecture
Sex and Gender in Governance: Transformation, Megatrends, and Public Health*
PD Dr. Ricarda Schmithausen, University Hospital Essen

*in cooperation with the lecture series “Resonance Spaces for Transformation – Opportunities for the Ruhr Region” by the UDE4future action group

Zoom link
© jannoon028/Freepik

ZMB/CRC1430 Seminars

08.09.2026with IMPRS-LM
Helen Walden
Molecular Biosciences, University of Glasgow

13.10.2026with CRC1430
Helle Ulrich, IMB Mainz
Ubiquitin, SUMO and genome maintenance , IMB Mainz

20.10.2026with CRC1430
Hiroaki Suga
Graduate School of Science, The University of Tokyo

24.11.2026with CRC1430
Janine Kirstein
Biochemistry of Aging, Fritz Lipmann Institute

12.01.2027
Chan Cao
Single-Molecule Bioanalysis, University of Geneva

Press Releases 2026

More ZMB Press Releases

Victoria Momand Portrait
© UDE/Fabian Strauch
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uni-due.de | Forschung fasziniert!

Was Promovierende an der UDE antreibt Victoria Momand

[01.06.2026] Wie fühlt sich Forschung im Alltag an? Victoria Momand gibt Einblicke in ihre Promotion, die von Neugier, Ideen und dem Wunsch geprägt ist, Zusammenhänge auf kleinster Ebene wirklich zu verstehen. Die Biologin zeigt, wie aus Fragen, Geduld und vielen kleinen Schritten Stück für Stück neue Erkenntnisse entstehen und warum Grundlagenforschung so wichtig ist.

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Das Bild zeigt die beteiligten Wissenschaftler:innen
© UDE/Nora Mitdank
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uni-due.de | Press release

Neuer Sonderforschungsbereich an der UDE Rund 12,9 Millionen Euro für Hautkrebsforschung

[15.05.2026] Großer Erfolg für die Universität Duisburg-Essen: Die Deutsche Forschungsgemeinschaft (DFG) richtet den Sonderforschungsbereich 1752 „DYNAMO“ ein. Ab dem 1. Oktober 2026 fördert sie die Forschung zur Verbesserung von Therapien gegen schwarzen Hautkrebs mit 12,9 Millionen Euro. Koordiniert wird der Forschungsverbund von Wissenschaftler:innen der Medizinischen Fakultät der Universität Duisburg-Essen gemeinsam mit Partnerinstitutionen aus Nordrhein-Westfalen.

ZMB Member: Prof. Dr. Alexander Roesch
ZMB Member: Prof. Dr. Kathrin Thedieck

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Das Bild zeigt das Innere einer Immunzelle: Zu sehen sind die Zellorganellen eines Neutrophilen – Endoplasmatisches Retikulum (blau), Lysosomen (gelb), Mitochondrien (violett), Lipidtröpfchen (cyan) und Golgi-Apparat (grün). Maßstab: 0,7 µm.
© Angelika Rambold
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uni-due.de | Press release

Sonderforschungsbereich verlängert Neue Sicht auf unterschätzte Immunzellen

[15.05.2026] Die Deutsche Forschungsgemeinschaft fördert den Sonderforschungsbereich/Transregio (TRR) 332 „Neutrophile: Entwicklung, Verhalten und Funktion“ für eine zweite Förderperiode mit rund 13 Millionen Euro. Am TRR 332 sind Wissenschaftler:innen der Medizinischen Fakultät der Universität Duisburg-Essen maßgeblich beteiligt.

ZMB Member: Prof. Dr. Jadwiga Jablonska-Koch
ZMB Member: Prof. Dr. Matthias Gunzer
ZMB Member: Prof. Dr. Sven Brandau
ZMB Member: Prof. Dr. Dirk M. Hermann

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© reerangestock.vom
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uni-due.de | Press release

Neue Humboldt-Stipendiat:innen Internationale Forschung an der UDE

[30.04.2026] Seit diesem Monat forschen fünf Wissenschaftler:innen mit einem Stipendium der Alexander von-Humboldt-Stiftung an der Universität Duisburg-Essen. Fachlich decken ihre Arbeiten verschiedene Bereiche ab, es geht um soziale, biologische, mechanische und rechtstheoretische Fragen. Mit einem Humboldt-Forschungsstipendium für erfahrene Forschende wird unter drei Wissenschaftlerinnen gefördert:

  • Die Stipendiatin Dr. Hanieh Jalali (Kharazmi University, Iran) widmet sich Problemen der Entwicklungsbiologie. Ihr Gastgeber ist Prof. Dr. Bernd Giebel vom UDE-Institut für Transfusionsmedizin.

ZMB Member: Prof. Dr. Bernd Giebel

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Pint of Science sign
© UDE/Peter Kohl
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uni-due.de | Press release

Pint of Science in Duisburg und Essen „Zwischen Bierglas und Weltuntergang“

[24.04.2026] Drei Abende, drei Locations, viele Perspektiven: Auch in diesem Jahr beteiligen sich Forschende der Universität Duisburg-Essen wieder am internationalen Format „Pint of Science“ und bringen aktuelle Forschung dorthin, wo man sie nicht unbedingt erwartet – in Bars und Kneipen. Vom 18. bis 20. Mai sprechen Wissenschaftler:innen verständlich, nahbar und mitten im Alltag über ihre Themen.
ZMB Member: Prof. Dr. Shirley Knauer

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© alexander-raths-stock.adobe.com
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uni-due.de | Press release

Forschende entdecken neuen Mechanismu Virusinfekte können Allergien verschärfen

[23.03.2026] Warum verlaufen allergische Reaktionen während einer Virusinfektion oft besonders schwer? Ein Forschungsteam der Medizinischen Fakultät der Universität Duisburg-Essen hat nun einen entscheidenden Mechanismus identifiziert: Bestimmte Immunzellen geraten im antiviralen Alarmzustand außer Kontrolle und können lebensbedrohliche allergische Reaktionen auslösen.
ZMB Member: Prof. Dr. Karl Sebastian Lang

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image representing research
© UDE/Frank Preuß
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uni-due.de | Press release

Neu an der UA Ruhr: Alpaslan Tasdogan Tumor-Stoffwechsel im Blick

[17.03.2026] Wie gelingt es Krebszellen zu überleben und sich im Körper auszubreiten? Dieser Frage widmet sich Prof. Dr. Dr. Alpaslan Tasdogan künftig am Research Center One Health der Universitätsallianz Ruhr. Der Dermato-Onkologe und Immunologe forscht seit vielen Jahren am Universitätsklinikum Essen zum Stoffwechsel von Tumoren. Seit dem 1. März 2026 ist er Professor für „Tumormetabolismus und Mikroenvironment“ im Research Center One Health.
ZMB Member: Prof. Dr. Alpaslan Tasdogan

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ZMB Research Programs

Oncology

The concept of this research program is to understand fundamental processes in tumor biology in order to develop novel molecularly defined and rationally applied cancer treatments.

Participating researchers from biology, experimental and clinical medicine study tumors as “biological systems" and so called “neo-organs”.

A large variety of approaches, experimental systems and methodologies are in place to analyse many aspects of tumor development, growth, progression and tumor cell migration.

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Immunology, Infectious Diseases and Transplantation

The immune system responds to various pathogens including viruses and bacteria in different ways to prevent severe disease and persistence in the host. Many pathogens, however, have developed mechanisms to evade immune defence.

The molecular and cellular interactions of pathogens with the immune system are studied within this program.

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Molecular and Chemical Cell Biology

Molecular and chemical cell biology is an interdisciplinary research program connecting molecular cell biology and genetics with chemistry and structural biology. Scientists of the participating disciplines collaborate to advance the understanding of basic molecular mechanisms of important biological processes.

The analysis of regulation and deregulation of key pathways is linking basic biology with pathophysiology.

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Latest Publications

    Journal articles

  • Li, Xin; Lebeaupin, Cynthia; Kadianaki, Aikaterini; Druelle-Cedano, Clementine; Vesper, Niklas; Rennert, Charlotte; Huguet-Pradell, Júlia; Gomez Ramos, Borja; Fan, Chaofan; Piecyk, Robert Stefan; Zizmare, Laimdota; Ramadori, Pierluigi; Li, Luqing; Frick, Lukas; Qiu, Menjie; Zhang, Cangang; Martins Nascentes Melo, Luiza; Ranvir, Vikas Prakash; Shen, Peng; Hanselmann, Johannes; Kosla, Jan; Fernández-Vaquero, Mirian; Vucur, Mihael; Baskaran, Praveen; Bao, Xuanwen; Coleman, Olivia I.; Tang, Yingyue; Cetin, Miray; Chen, Zhouji; Jang, Insook; Del Prete, Stefania; Rahbari, Mohammad; Zhang, Peng; Pham, Timothy V.; Hou, Yushan; Sun, Aihua; Gu, Li; Kim, Laura C.; Rothermel, Ulrike; Heide, Danijela; Ali, Adnan; Gallage, Suchira; Talvard-Balland, Nana; Piqué-Gili, Marta; Gris-Oliver, Albert; Bevilacqua, Alessio; Schlicker, Lisa; Duffey, Alec; Unger, Kristian; Szydlowska, Marta; Hetzer, Jenny; Odom, Duncan T.; Machauer, Tim; Bucci, Daniele; Sant, Pooja; Lee, Jun-Hoe; Rösler, Jonas; Meckelmann, Sven; Schreck, Johannes; Murray, Sue; Simon, M. Celeste; Nahnsen, Sven; Schulze, Almut; Ho, Ping-Chih; Jugold, Manfred; Breuhahn, Kai; Mallm, Jan-Philipp; Schirmacher, Peter; Roth, Susanne; Rahbari, Nuh; Tschaharganeh, Darjus F.; Roessler, Stephanie; Goeppert, Benjamin; Bengsch, Bertram; Andrieux, Geoffroy; Boerries, Melanie; Malek, Nisar P.; Prinz, Marco; Weber, Achim; Zeiser, Robert; Tamayo, Pablo; Bronsert, Peter; Kurowski, Konrad; Thimme, Robert; Yuan, Detian; Carretero, Rafael; Luedde, Tom; Pinyol, Roser; Hartmann, Felix J.; Karin, Michael; Tasdogan, Alpaslan; Trautwein, Christoph; Mall, Moritz; Hofmann, Maike; Llovet, Josep M.; Haller, Dirk; Kaufman, Randal J.; Heikenwälder, Mathias
    Activated ATF6α is a hepatic tumour driver restricting immunosurveillance
    In: Nature, 2026, in press
    DOI (Open Access)
  • Napolitano, Andrea; Joensuu, Heikki; Rothschild, Sara; Evans, Denisse; Heinrich, Michael C.; Sutton, Thomas L.; Mayo, Skye C.; Boye, Kjetil; Falkenhorst, Johanna; Le Cesne, Axel; Hohenberger, Peter; Rutkowski, Piotr; van Houdt, Winan J.; Steeghs, Neeltje; Gelderblom, Hans; Desar, Ingrid M.E.; Pantaleo, Maria A.; Nishida, Toshiro; Reichardt, Peter; Blay, Jean-Yves; Somaiah, Neeta; Nassif Haddad, Elise F.; Grignani, Giovanni; Baldi, Giacomo G.; Steigen, Sonja E.; Braconi, Chiara; Nilsson, Bengt; Singh, Arun S.; Fumagalli, Elena; Cananzi, Ferdinando C.M.; Italiano, Antoine; Ceruso, Mariella Spalato; Brunello, Antonella; Magnússon, Magnús K.; Jonasson, Jon G.; Marquina, Gloria; Hindi, Nadia; Cirilli, Claudia; Federico, Massimo; Fausti, Valentina; Bordoni, Andrea; Sufliarsky, Jozef; Mazzocca, Alessandro; Martin-Broto, Javier; Gronchi, Alessandro; Trent, Jonathan C.; Casali, Paolo G.; Bauer, Sebastian; Jones, Robin L.; Vincenzi, Bruno
    Adjuvant Imatinib or Observation in Patients with Gastrointestinal Stromal Tumors with KIT Exon 9 Mutations
    In: JAMA Oncology, Vol. 12, 2026, Nr. 4, pp. 407 – 412
    DOI
  • Weil, Tatjana; Lawrenz, Jan; Taghuo Kaptouom, Estelle; Mieres-Perez, Joel; Hunszinger, Victoria; Sparrer, Konstantin M J; Almeida-Hernandez, Yasser; Schrader, Thomas; Sanchez-Garcia, Elsa; Münch, Jan
    Advanced Molecular Tweezers Effectively Target Membranes Lacking Choline Headgroups for Broad-Spectrum Antiviral Efficacy
    In: Journal of the American Chemical Society: JACS, Vol. 148, 2026, Nr. 3, pp. 3626 – 3637
    DOI (Open Access)
  • Haase, Max A. B.; Lazar-Stefanita, Luciana; Baudry, Lyam; Wudzinska, Aleksandra; Zhou, Xiaofan; Rokas, Antonis; Hittinger, Chris Todd; Pfander, Boris; Musacchio, Andrea; Boeke, Jef D.
    Ancient co-option of LTR retrotransposons as yeast centromeres
    In: Nature, 2026, in press
    DOI (Open Access)
  • Tayyebi, Ebrahim; Exner, Kai
    Atomic-Scale Understanding of Selectivity Control in Nitrate Reduction on Cu(100) Under Acidic and Alkaline Conditions
    In: Angewandte Chemie International Edition, 2026, in press
    DOI (Open Access)
  • Bolli, Evangelia; Wirapati, Pratyaksha; Hicham, Mehdi; Xie, Yuxuan; Siwicki, Marie; Duval, Florent; Goubet, Anne-Gaëlle; Kiss, Máté; Zitti, Béatrice; Zwahlen, Thomas; Mcdowell, Sheri; Bill, Ruben; Angerani, Simona; Engblom, Camilla; Anderson, Seth; Jiang, Aiping; Hartley, Oliver; Sykes, David B.; Jankovic, Maja; Fournier, Nadine; Gunzer, Matthias; Tarussio, David; Tissot, Stéphanie; Sadow, Peter M.; Faquin, William C.; Sade-Feldman, Moshe; Weissleder, Ralph; Pai, Sara; Mercier, François; Manguso, Robert; Pittet, Mikaël J.
    CCL3 is produced by aged neutrophils across cancers and promotes tumor growth
    In: Cancer Cell, Vol. 44, 2026, Nr. 3, pp. 624 – 640.e12
    DOI (Open Access)
  • Kremer, Nora; Mueller, Franziska; Nguyen, Hang; Schulz, Louisa; Popp, Tanja; Artes, Elena; Wolters, Julian; Renner, Michael; Vetter, Ingrid; Maffini, Stefano; Robles, Maria S.; Musacchio, Andrea; Bange, Tanja
    CUL4A-DDB1-DCAF10 is an N-recognin for N-terminally acetylated Src kinases
    In: Nature Communications, Vol. 17, 2026, Nr. 1, 132
    DOI (Open Access)
  • Peng, JuanFei; Yang, JiaJin; Antonopoulou, Georgia; Fang, Rui; Adhikari, Bikash; Vogt, Markus; Wolf, Elmar; Sun, Chong; Du, Shangce; Godfrey, Laura; Gupta, Aayush; Trajkovic-Arsic, Marija; Teichmann, Nicole; Grünwald, Barbara T.; Krebs, Niklas; Steiger, Katja; Mogler, Carolin; Althoff, Kristina; Wang, Xin; Giglio, Giovanni; Liffers, Sven-Thorsten; Savvatakis, Konstantinos; Braren, Rickmer; Lawlor, Rita T.; Scarpa, Aldo; Behrens, Diana; Lang, Karl S.; Cheung, Phyllis F.; Siveke, Jens T.
    Combined targeted and epigenetic-based therapy enhances antitumor immunity by stabilizing GATA6-dependent MHCI expression in pancreatic ductal adenocarcinoma
    In: Nature Communications, Vol. 17, 2026, Nr. 1, 1476
    DOI (Open Access)
  • Kassar, Mohammad; Praz, Fabien; Gercek, Muhammed; Fortmeier, Vera; Kresoja, Karl-Patrik; Stein, Jennifer von; Pauschinger, Christoph; Rottbauer, Wolfgang; Goebel, Bjoern; Denti, Paolo; Achouh, Paul; Rassaf, Tienush; Barreiro-Perez, Manuel; Boekstegers, Peter; Ruck, Andreas; Zdanyte, Monika; Adamo, Marianna; Vincent, Flavien; Schlegel, Philipp; Rosch, Sebastian; Wild, Mirjam G.; Besler, Christian; Toggweiler, Stefan; Brunner, Stephanie; Grapsa, Julia; Patterson, Tiffany; Thiele, Holger; Kister, Tobias; Tarantini, Giuseppe; Masiero, Giulia; De Carlo, Marco; Sticchi, Alessandro; Voss, Fabian; Polzin, Amin; Rubbio, Antonio Popolo; Bedogni, Francesco; Konstandin, Mathias H.; Van Belle, Eric; Metra, Marco; Geisler, Tobias; Estevez-Loureiro, Rodrigo; Mahabadi, Amir; Karam, Nicole; Maisano, Francesco; Lauten, Philipp; Kessler, Mirjam; Kalbacher, Daniel; Iliadis, Christos; Lurz, Philipp; Hausleiter, Jorg; Mahfoud, Felix; Windecker, Stephan; Stolz, Lukas; Brugger, Nicolas; Rudolph, Volker
    Combined transcatheter mitral and tricuspid edge-to-edge repair or tricuspid edge-to-edge repair alone in moderate mitral regurgitation : a propensity-matched analysis
    In: European Heart Journal, 2026, in press
    DOI (Open Access)
  • Liu, Mei; Wei, You; Weber, Lisa-Marie; Mladenov, Emil; Lin, Xixi; Mladenova, Veronika; Shafaat, Ramtin Omid; Pantelias, Gabriel E.; Gkika, Eleni; Stuschke, Martin; Soni, Aashish; Iliakis, George
    Condensins regulate resection-dependent DNA double-strand break repair pathways in replicated chromatin
    In: Nucleic Acids Research, Vol. 54, 2026, Nr. 4, gkag076
    DOI (Open Access)
  • Zhang, Ruirui; Liu, Jie; Gasper, Raphael; Unger, Anke; Kaschani, Farnusch; Kaiser, Markus; Janning, Petra; Waldmann, Herbert
    Covalent modification of a glutamic acid inspired by HaloTag technology
    In: Nature Communications, Vol. 17, 2026, Nr. 1, 1257
    DOI (Open Access)
  • Keyl, Julius; Hosch, René; Hörst, Fabian; Keyl, Philipp; Dada, Amin; Haubold, Johannes; Straus, Jannis; Egger, Jan; Stahler, Arndt; Kurreck, Annika; Ballhausen, Alexej; Stintzing, Sebastian; Fruehauf, Stefan; Müller, Lothar; Alig, Annabel H S; Trarbach, Tanja; Hartmann, Sylvia; Nensa, Felix; Kleesiek, Jens; Kasper, Stefan; Schuler, Martin; Modest, Dominik P.
    Deep Learning-Derived Sarcopenia Marker Predicts Benefit from Anti-EGFR Therapy in Patients with RAS Wild-type Metastatic Colorectal Cancer
    In: Clinical Cancer Research, Vol. 32, 2026, Nr. 5, pp. 938 – 946
    DOI (Open Access)
  • Eberle, Julia; Salem, Ahmed; Hofmann, Mara; Reisser, Anja; Ruiz-Blanco, Yasser B.; Almeida-Hernandez, Yasser; Gole, Boris; Rall-Scharpf, Melanie; Angulo-Capel, Jessica; Monecke, Thomas; Sanchez-Garcia, Elsa; Gebhardt, J Christof M; Wiesmüller, Lisa
    Discovery of an Endonuclease G-inhibitory Ku80-peptide protecting against leukemogenic rearrangements at the MLL breakpoint cluster
    In: Nature Communications, Vol. 17, 2026, Nr. 1, 3562
    DOI (Open Access)
  • Dummer, Reinhard; Deng, Shibing; Xie, Tao; Pathan, Nuzhat; Saffari, Hedieh; Robert, Caroline; Arance, Ana; de Groot, Jan Willem B.; Garbe, Claus; Gogas, Helen J.; Gutzmer, Ralf; Krajsová, Ivana; Liszkay, Gabriella; Loquai, Carmen; Mandala, Mario; Schadendorf, Dirk; Yamazaki, Naoya; Ascierto, Paolo A.; Davis, Craig B.; Shah, Khyati; Hamilton, Phineas; di Pietro, Alessandra; Flaherty, Keith
    Exploratory Analysis of Biomarkers and Treatment Outcomes from the COLUMBUS Study in BRAF V600E/K–Mutant Advanced or Metastatic Melanoma
    In: Clinical Cancer Research, Vol. 32, 2026, Nr. 7, pp. 1266 – 1276
    DOI (Open Access)
  • Anker, Markus S.; Mahabadi, Amir Abbas; Totzeck, Matthias; Tewes, Mitra; Khan, Muhammad Shahzeb; Mincu, Raluca; Hendgen-Cotta, Ulrike B.; Michel, Lars; Mathew, Baicy; Drescher, Ophelia; Schuler, Martin; Keller, Ulrich; Rieger, Kathrin; Ahn, Johann; Bullinger, Lars; Modest, Dominik P.; Denecke, Corinna; Kretzler, Lucie; Ramer, Luisa V.; Krug, Danara; Landmesser, Ulf; Lehmann, Lorenz H.; Frey, Norbert; Bercker, Sven; Laufs, Ulrich; Böhm, Michael; Mahfoud, Felix; Merkely, Bela; Diek, Monika; Butler, Javed; Veiser, Anja; Heise, Tim; Hellmich, Martin; Placzek, Marius; Friede, Tim; Anker, Stefan D.; Rassaf, Tienush
    Heart failure therapy in patients with advanced cancer receiving specialized palliative care (EMPATICC trial)
    In: European Heart Journal, Vol. 47, 2026, Nr. 9, pp. 1034 – 1046
    DOI (Open Access)
  • Hassel, J.C.; Arance, A.; Carlino, M.S.; Mortier, L.; Ascierto, P.A.; Rutkowski, P.; Sandhu, S.; Coetzee, C.; Puzanov, I.; Karaca, S.B.; Eggermont, A.M.; Hamid, O.; Grabbe, S.; Poklepovic, A.; Amaral, T.; Schadendorf, Dirk; Schilling, Bastian; Vedel Christiansen, A.; Wang, B.; Wakatsuki Pedersen, A.; Ahmad, Q.; Zocca, M.B.; Ringeisen, F.; Robert, C.; Svane, I.M.
    IO102-IO103 immune-modulatory cancer vaccine and pembrolizumab in melanoma
    In: Annals of Oncology, 2026, in press
    DOI (Open Access)
  • Albers, Malena; Bosse, Lydia; Schröter, Larissa; Junemann, Anna-Maria T.; Rossdam, Charlotte; Hartmann, Maike; Grove, Melanie; Litfin, Thomas; Egger, Anna-Sophia; Kwiatkowski, Marcel; Thedieck, Kathrin; Zocher, Georg; Buettner, Falk F. R.; Malde, Alpeshkumar K.; von Itzstein, Mark; Mühlenhoff, Martina
    Interplay of SLC33A1-dependent and -independent Golgi sialic acid O-acetylation in CASD1 catalysis
    In: Nature Communications, Vol. 17, 2026, Nr. 1, 3156
    DOI, Online Full Text (Open Access)
  • Walstein, Kai; Hill, Louisa; Vogt, Doro; Oberste-Lehn, Lina; Janning, Petra; Vetter, Ingrid R; Pan, Dongqing; Musacchio, Andrea
    M18BP1 valency and a distributed interaction footprint determine epigenetic centromere specification in humans
    In: The EMBO Journal, 2026, in press
    DOI (Open Access)
  • Ren, Long; Esposito-Verza, Arianna; Gasper, Raphael; Pesenti, Marion E.; Janning, Petra; Müller, Franziska; Koerner, Carolin; Geue, Petra; Wohlgemuth, Sabine; Vetter, Ingrid R.; Musacchio, Andrea
    Molecular anatomy of PLK1 master docking motifs
    In: Nature Communications, Vol. 17, 2026, Nr. 1, 4228
    DOI (Open Access)
  • Esposito-Verza, Arianna; Conti, Duccio; Rodrigues Pedroso, Paulo D.; Oberste-Lehn, Lina; Koerner, Carolin; Wohlgemuth, Sabine; Mansurkhodzhaev, Artem; Vetter, Ingrid R.; Pesenti, Marion E.; Musacchio, Andrea
    Molecular requirements for PLK1 activation by T-loop phosphorylation
    In: The EMBO Journal, Vol. 45, 2026, Nr. 5, pp. 1496 – 1536
    DOI (Open Access)
  • Renner, Marcus; Oleś, Małgorzata; Paramasivam, Nagarajan; Heilig, Christoph E.; Schneider, Annika; Modugno, Caroline; Herremans, Catherine; Hüllein, Jennifer; Hutter, Barbara; Erkut, Cihan; Mock, Andreas; Krieghoff-Henning, Eva; Jensen, Cecilia B.; Sakhteman, Amirhossein; The, Matthew; Prinz, Tony; Lajer, Panna; Baude-Müller, Annika; Beck, Katja; Beuthien-Baumann, Bettina; Apostolidis, Leonidas; Bauer, Sebastian; Boerries, Melanie; Brandts, Christian H.; Rieke, Damian T.; Kindler, Thomas; Klauschen, Frederick; Schulze-Osthoff, Klaus; Schlenk, Richard F.; Berchem, Guy; Allgäuer, Michael; Mechtersheimer, Gunhild; Stenzinger, Albrecht; Lipka, Daniel B.; Schlesner, Matthias; Kuster, Bernhard; Jahn, Arne; Schröck, Evelin; Heining, Christoph; Teleanu, Maria-Veronica; Horak, Peter; Kreutzfeldt, Simon; Hübschmann, Daniel; Hartmann, Wolfgang; Glimm, Hanno; Fröhling, Stefan
    Multi-layered molecular profiling informs the diagnosis and targeted therapy of desmoplastic small round cell tumor
    In: Nature Communications, Vol. 17, 2026, Nr. 1, 3397
    DOI (Open Access)
  • Werr, Lisa; Boland, Jana; Petersen, Josephine; Iglesias, Fiorella; Höppner, Stefanie; Bartenhagen, Christoph; Rosswog, Carolina; Hellmann, Anna-Maria; Kahlert, Yvonne; Hemstedt, Nadine; Ibruli, Nadliv; Dammert, Marcel A.; Decarolis, Boris; Werner, Jan-Michael; Malchers, Florian; Schramm, Kathrin; Witt, Olaf; Beiske, Klaus H.; Rognlien, Anne Gro Wesenberg; Gunnes, Maria Winther; Langenberg, Karin P.; Molenaar, Jan; Bernkopf, Marie; Taschner-Mandl, Sabine; Hughes, Debbie; George, Sally L.; Chesler, Louis; Schulte, Johannes H.; Barone, Giuseppe; Capasso, Mario; Surrey, Lea F.; Bagatell, Rochelle; Masliah-Planchon, Julien; Schleiermacher, Gudrun; Grüll, Holger; Westermann, Frank; Schultheis, Anne M.; Büttner, Reinhard; Henssen, Anton G.; Eggert, Angelika; Peifer, Martin; Shukla, Neerav N.; Simon, Thorsten; Hero, Barbara; Reinhardt, H. Christian; Thomas, Roman K.; Fischer, Matthias
    Mutated FGFR1 is an oncogenic driver and therapeutic target in high-risk neuroblastoma
    In: The Journal of Clinical Investigation (JCI), Vol. 136, 2026, Nr. 7, 189152
    DOI (Open Access)
  • Wutz, Gordana; Davidson, Iain F.; Banigan, Edward J.; Stocsits, Roman R.; Kawasumi, Ryotaro; Tang, Wen; Nagasaka, Kota; Costantino, Lorenzo; Jansen, Ralf; Hirota, Kouji; Branzei, Dana; Mirny, Leonid A.; Peters, Jan-Michael
    PDS5 proteins control genome architecture by limiting the lifetime of cohesin-NIPBL complexes
    In: Molecular Cell, 2026, in press
    DOI (Open Access)
  • Frost, Nikolaj; Joosten, M.; Franzen, J.; Wiesweg, Marcel; Rasokat, A.; Kulhavy, J.; Kollmeier, J.; Reinmuth, N.; Grohé, C.; Roeper, J.; Rittmeyer, A.; Heinzen, S.; Wermke, M.; Wesseler, C.; Christopoulos, P.; Kauffmann-Guerrero, D.; Althoff, A.; Bleckmann, A.; Collienne, M.; Berezucki, E.; Overbeck, T.; Kropf-Sanchen, C.; Griesinger, F.; Sebastian, M.; Schuler, Martin; Braun, S.; Wenzel, C.; Furth, C.; Wolf, J.; Bischoff, P.; Reck, M.; National Network Genomic Medicine Lung Cancer Germany
    PET/CT-guided management of immune checkpoint blockade and multi-modal profiling following treatment in long-term responders with metastatic lung cancer in the National Network Genomic Medicine Lung Cancer Germany (nNGM)
    In: Annals of Oncology, Vol. 37, 2026, Nr. 5, pp. 686 – 700
    DOI (Open Access)
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