IMCES Publikationen der 2020er


During early stages of cancer, neutrophils initiate anti-tumor immune responses in tumor-draining lymph nodes
Cell Reports; 2022-08-16; 40(7): ; doi:https://doi.org/10.1016/j.celrep.2022.111171
https://www.sciencedirect.com/science/article/pii/S2211124722009846?via%3Dihub
Ekaterina Pylaeva, Georg Korschunow, Ilona Spyra, Sharareh Bordbari, Elena Siakaeva, Irem Ozel, Maksim Domnich, Anthony Squire, Anja Hasenberg, Kruthika Thangavelu, Timon Hussain, Moritz Goetz, Karl S. Lang, Matthias Gunzer, Wiebke Hansen, Jan Buer, Agnes Bankfalvi, Stephan Lang, Jadwiga Jablonska


https://pubmed.ncbi.nlm.nih.gov/35969658/
Deciphering the Emulsification Process to Create an Albumin-Perfluorocarbon-(o/w) Nanoemulsion with High Shelf Life and Bioresistivity
Langmuir; 2022-08-15; (): ; doi:10.1021/acs.langmuir.1c03388

Johannes Jaegers*, Sven Haferkamp, Oliver Arnolds, Daniel Moog, Anna Wrobeln, Fabian Nocke, Miriam Cantore, Stefanie Pütz, Anne Hartwig, Rico Franzkoch, Olympia Ekaterini Psathaki, Holger Jastrow, Carsten Schauerte, Raphael Stoll, Michael Kirsch, and Katja Bettina Ferenz*



Platelet depletion does not alter long-term functional outcome after cerebral ischaemia in mice
Brain, Behavior, & Immunity - Health; 2022-07-21; (): ; doi:10.1016/j.bbih.2022.100493

Rebecca D. Steubing, Fabian Szepanowski, Christina David, Ayan Mohamud Yusuf, Stine Mencl, Anne-Kathrin Mausberg, Harald F. Langer, Manuela Sauter, Cornelius Deuschl, Michael Forsting, Anke C. Fender, Dirk M. Hermann, Ana I. Casas, Friederike Langhauser, Christoph Kleinschnitz



ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning.
Development; 2022-07-01; 149(13): ; doi:https://doi.org/10.1242/dev.200528
https://journals.biologists.com/dev/article/149/13/dev200528/275974/ERG-activity-is-regulated-by-endothelial-FAK
Gabriela D'Amico, Isabelle Fernandez, Jesús Gómez-Escudero, Hyojin Kim, Eleni Maniati, Muhammad Syahmi Azman, Faraz K. Mardakheh, Bryan Serrels, Alan Serrels, Maddy Parsons, Anthony Squire, Graeme M. Birdsey, Anna M. Randi, Alfonso Bolado-Carrancio, Rathi Gangeswaran, Louise E. Reynolds, Natalia Bodrug, Yaohe Wang, Jun Wang, Pascal Meier, Kairbaan M. Hodivala-Dilke



Design and Functional Characterization of HIV-1 Envelope Protein-Coupled T Helper Liposomes
Pharmaceutics; 2022-06-30; 14(7): 1385; doi:10.3390/pharmaceutics14071385
https://www.mdpi.com/1999-4923/14/7/1385
Dominik Damm , Ehsan Suleiman , Hannah Theobald , Jannik T. Wagner , Mirjam Batzoni , Bianca Ahlfeld (née Kohlhauser) , Bernd Walkenfort , Jens-Christian Albrecht , Jidnyasa Ingale , Lifei Yang , Mike Hasenberg , Richard T. Wyatt , Karola Vorauer-Uhl , Klaus Überla and Vladimir Temchura



IFNAR1 Deficiency Impairs Immunostimulatory Properties of Neutrophils in Tumor-Draining Lymph Nodes.
Frontiers in Immunology; 2022-06-27; 13(): ; doi:10.3389/fimmu.2022.878959
https://www.frontiersin.org/articles/10.3389/fimmu.2022.878959/full
Hussain T, Domnich M, Bordbari S, Pylaeva E, Siakaeva E, Spyra I, Ozel I, Droege F, Squire A, Lienenklaus S, Sutter K, Hasenberg A, Gunzer M, Lang S, Jablonska J


https://pubmed.ncbi.nlm.nih.gov/35697379/
Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity
Journal for ImmunoTherapie of Cancer; 2022-06-23; 10(6): ; doi:10.1136/jitc-2021-003863
https://jitc.bmj.com/content/10/6/e003863
Beatrice Thier, Fang Zhao, Simone Stupia, Alicia Brüggemann, Johannes Koch, Nina Schulze, Susanne Horn, Christoph Coch, Gunther Hartmann 5, Antje Sucker, Dirk Schadendorf, Annette Paschen


https://pubmed.ncbi.nlm.nih.gov/33784074/
Gold Nanorods Induce Endoplasmic Reticulum Stress and Autocrine Inflammatory Activation in Human Neutrophils
ACS Nano; 2022-06-23; 16(4): ; doi:10.1021/acschembio.0c00757
https://pubs.acs.org/doi/full/10.1021/acsnano.2c03586
Ronja Schirrmann, Michael Erkelenz, Kim Lamers, Oliver Sritharan, Milen Nachev, Bernd Sures, Sebastian Schlücker, and Sven Brandau



Bacteria (E. coli ) take up ultrasmall gold nanoparticles (2 nm) as shown by different optical microscopic techniques (CLSM, SIM, STORM)
Nano Select; 2022-06-14; (): ; doi:10.1002/nano.202200049
https://onlinelibrary.wiley.com/doi/full/10.1002/nano.202200049
Nataniel Bia?as,Viktoriya Sokolova,Selina Beatrice van der Meer,Torben Knuschke,Tatjana Ruks,Kai Klein,Astrid M. Westendorf,Matthias Epple


https://pubmed.ncbi.nlm.nih.gov/35697379/
Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity
Journal for ImmunoTherapie of Cancer; 2022-06-10; 6(): ; doi:10.1136/jitc-2021-003863
https://jitc.bmj.com/content/10/6/e003863.long
Beatrice Thier, Fang Zhao, Simone Stupia, Alicia Brüggemann, Johannes Koch, Nina Schulze, Susanne Horn, Christoph Coch, Gunther Hartmann, Antje Sucker, Dirk Schadendorf, Annette Paschen


https://pubmed.ncbi.nlm.nih.gov/35650266/
Persister state-directed transitioning and vulnerability in melanoma.
Nature Communications; 2022-06-01; 13(1): 3055; doi:https://doi.org/10.1038/s41467-022-30641-9
https://doi.org/10.1038/s41467-022-30641-9
Chauvistré H, Shannan B, Daignault-Mill SM, Ju RJ, Picard D, Egetemaier S, Váraljai R, Gibhardt CS, Sechi A, Kaschani F, Keminer O, Stehbens SJ, Liu Q, Yin X, Jeyakumar K, Vogel FCE, Krepler C, Rebecca VW, Kubat L, Lueong SS, Forster J, Horn S, Remke M, Ehrmann M, Paschen A, Becker JC, Helfrich I, Rauh D, Kaiser M, Gul S, Herlyn M, Bogeski I, Rodríguez-López JN, Haass NK, Schadendorf D, Roesch A.


https://pubmed.ncbi.nlm.nih.gov/35609021/
Long-term treatment with chloroquine increases lifespan in middle-aged male mice possibly via autophagy modulation, proteasome inhibition and glycogen metabolism.
Aging; 2022-05-23; 14(): ; doi:10.18632/aging.204069
https://www.aging-us.com/article/204069/text
Doeppner TR, Coman C, Burdusel D, Ancuta DL, Brockmeier U, Pirici DN, Yaoyun K, Hermann DM, Popa-Wagner A


https://pubmed.ncbi.nlm.nih.gov/35565295/
RB1-Negative Retinal Organoids Display Proliferation of Cone Photoreceptors and Loss of Retinal Differentiation
Cancers; 2022-04-26; 14(9): 2166; doi:10.3390/cancers14092166

Kanber D, Woesfeld J, Döpper H, Bozet M, Brenzel A, Altmüller J, Kilpert D, Pommerenke C, Steenpass L


https://pubmed.ncbi.nlm.nih.gov/34530440/
Sublamina-Specific Dynamics and Ultrastructural Heterogeneity of Layer 6 Excitatory Synaptic Boutons in the Adult Human Temporal Lobe Neocortex.
Cerebral Cortex; 2022-04-20; 32(9): 1840-1865; doi: https://doi.org/10.1093/cercor/bhab315
https://academic.oup.com/cercor/advance-article/doi/10.1093/cercor/bhab315/6371350
Schmuhl-Giesen S, Rollenhagen A, Walkenfort B, Yakoubi R, Sätzler K, Miller D, von Lehe M, Hasenberg M, Lübke JHR



Efficient Small Extracellular Vesicles (EV) Isolation Method and Evaluation of EV-Associated DNA Role in Cell–Cell Communication in Cancer
Cancers; 2022-04-20; 14(9): 2068; doi:https://doi.org/10.3390/cancers14092068
https://doi.org/10.3390/cancers14092068
Chetty VK, Ghanam J, Anchan S, Reinhardt K, Brenzel A, Gelléri M, Cremer C, Grueso-Navarro E, Schneider M, von Neuhoff N, Reinhardt D, Jablonska J, Nazarenko I, Thakur BK


https://pubmed.ncbi.nlm.nih.gov/34751438/
SIRT1-mediated deacetylation of FOXO3a transcription factor supports pro-angiogenic activity of interferon-deficient tumor-associated neutrophils
International Journal of cancer; 2022-04-01; 150(7): 1198-1211; doi:10.1002/ijc.33871
https://onlinelibrary.wiley.com/doi/10.1002/ijc.33871
Bordbari S, Mörchen B, Pylaeva E, Siakaeva E, Spyra I, Domnich M, Droege F, Kanaan O, Lang KS, Schadendorf D, Lang S, Helfrich I, Jablonska J



Free flow electrophoresis allows quick and reproducible preparation of extracellular vesicles from conditioned cell culture media
Extracellular Vesicles and Circulating Nucleic Acids; 2022-03-22; 3(): 31-48; doi:
https://evcna.com/article/view/4702
Staubach S, Tertel T, Walkenfort B, Buschmann D, Pfaffl MW, Weber G, Giebel B


https://pubmed.ncbi.nlm.nih.gov/35289361/
Inhibition of azole-resistant Aspergillus fumigatus biofilm at various formation stages by antifungal drugs, including olorofim
Journal of Antimicrobial Chemotherapy; 2022-03-15; (): ; doi:10.1093/jac/dkac062
https://academic.oup.com/jac/advance-article/doi/10.1093/jac/dkac062/6548677
Kirchhoff L, Dittmer S, Furnica DT, Buer J, Steinmann E, Rath PM, Steinmann J


https://pubmed.ncbi.nlm.nih.gov/34779257/
An Early Wave of Macrophage Infiltration Intertwined with Antigen-Specific Proinflammatory T Cells and Browning of Adipose Tissue Characterizes the Onset of Orbital Inflammation in a Mouse Model of Graves' Orbitopathy.
Thyroid; 2022-03-01; 32(3): 283-293; doi:10.1089/thy.2021.0464
https://www.liebertpub.com/doi/10.1089/thy.2021.0464?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed
Philipp S, Horstmann M, Hose M, Daser A, Görtz GA, Jesenek C, Flögel U, Hansen W, Bechrakis N, Banga JPS, Eckstein A, Berchner-Pfannschmidt U


https://pubmed.ncbi.nlm.nih.gov/35251021/
Reactivity of NK Cells Against Ovarian Cancer Cells Is Maintained in the Presence of Calcium Phosphate Nanoparticles
Frontiers in Immunology; 2022-02-18; 13(830938): ; doi:https://doi.org/10.3389/fimmu.2022.830938
https://www.frontiersin.org/articles/10.3389/fimmu.2022.830938/full
Hrvat A, Schmidt M, Obholzer M, Benders S, Kollenda S, Horn PA, Epple M, Brandau S, Mallmann-Gottschalk N


https://pubmed.ncbi.nlm.nih.gov/35159369/
Induction of Survival of Motor Neuron (SMN) Protein Deficiency in Spinal Astrocytes by Small Interfering RNA as an In Vitro Model of Spinal Muscular Atrophy
Cells; 2022-02-05; 11(3): 558; doi:10.3390/cells11030558
https://www.mdpi.com/2073-4409/11/3/558/htm
Leo M, Schmitt LI, Fleischer M, Steffen R, Osswald C, Kleinschnitz C, Hagenacker T


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834272/
Distinct Actions of the Thyroid Hormone Transporters Mct8 and Oatp1c1 in Murine Adult Hippocampal Neurogenesis
Cells; 2022-02-02; 11(3): 524; doi:https://doi.org/10.3390/cells11030524
https://www.mdpi.com/2073-4409/11/3/524/htm
Mayerl S, Alcaide Martin A, Bauer R, Schwaninger M, Heuer H, Ffrench-Constant C


https://pubmed.ncbi.nlm.nih.gov/34848338/
Post-ischemic protein restriction induces sustained neuroprotection, neurological recovery, brain remodeling, and gut microbiota rebalancing.
Brain, Behavior, and Immunity; 2022-02-01; 100(): 134-144; doi: 10.1016/j.bbi.2021.11.016
https://www.sciencedirect.com/science/article/pii/S0889159121006127
de Carvalho TS, Singh V, Yusuf AM, Wang J, Schultz Moreira AR, Sanchez-Mendoza EH, Sardardi M, Nascentes Melo LM, Doeppner TR, Kehrmann J, Scholtysik R, Hitpass L, Gunzer M, Hermann DM


https://pubmed.ncbi.nlm.nih.gov/34389849/
Targeting early stages of cardiotoxicity from anti-PD1 immune checkpoint inhibitor therapy.
European Heart Journal; 2022-01-31; (): ; doi: 10.1093/eurheartj/ehab430
https://academic.oup.com/eurheartj/advance-article-abstract/doi/10.1093/eurheartj/ehab430/6352226?redirectedFrom=fulltext
Michel L, Helfrich I, Hendgen-Cotta UB, Mincu RI, Korste S, Mrotzek SM, Spomer A, Odersky A, Rischpler C, Herrmann K, Umutlu L, Coman C, Ahrends R, Sickmann A, Löffek S, Livingstone E, Ugurel S, Zimmer L, Gunzer M, Schadendorf D, Totzeck M, Rassaf T


https://pubmed.ncbi.nlm.nih.gov/35100966/
Characterisation of cold-induced mitochondrial fission in porcine aortic endothelial cells.
Journal of Molecular Medicine; 2022-01-31; 28(1): ; doi:10.1186/s10020-021-00430-z
https://molmed.biomedcentral.com/articles/10.1186/s10020-021-00430-z
Quiring L, Walter B, Lohaus N, Schwan D, Rech A, Dlugos A, Rauen U


https://pubmed.ncbi.nlm.nih.gov/35038735/
Canonical Thyroid Hormone Receptor ? Action Stimulates Hepatocyte Proliferation in Male Mice
Endocrinology; 2022-01-17; 163(3): ; doi:10.1210/endocr/bqac003
https://academic.oup.com/endo/article/163/3/bqac003/6509895?login=true#330181598
Hönes GS, Kerp H, Hoppe C, Kowalczyk M, Zwanziger D, Baba HA, Führer D, Moeller LC


https://pubmed.ncbi.nlm.nih.gov/34339499/
Thyroid Hormone Transporter Deficiency in Mice Impacts Multiple Stages of GABAergic Interneuron Development.
Cerebral Cortex; 2022-01-10; 32(2): 329-341; doi:10.1093/cercor/bhab211
https://academic.oup.com/cercor/article/32/2/329/6333075?login=false
Mayerl S, Chen J, Salveridou E, Boelen A, Darras VM, Heuer H


https://pubmed.ncbi.nlm.nih.gov/35013174/
Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression.
Nature communications; 2022-01-10; 13(1): 156; doi:https://doi.org/10.1038/s41467-021-27088-9
https://www.nature.com/articles/s41467-021-27088-9
Cheung PF, Yang J, Fang R, Borgers A, Krengel K, Stoffel A, Althoff K, Yip CW, Siu EHL, Ng LWC, Lang KS, Cham LB, Engel DR, Soun C, Cima I, Scheffler B, Striefler JK, Sinn M, Bahra M, Pelzer U, Oettle H, Markus P, Smeets EMM, Aarntzen EHJG, Savvatakis K, Liffers ST, Lueong SS, Neander C, Bazarna A, Zhang X, Paschen A, Crawford HC, Chan AWH, Cheung ST, Siveke JT.


https://pubmed.ncbi.nlm.nih.gov/34921500/
Enhancement of proton therapy efficiency by noble metal nanoparticles is driven by the number and chemical activity of surface atoms.
Small Structures; 2021-12-17; (): ; doi:10.1002/smll.202106383
https://onlinelibrary.wiley.com/doi/10.1002/smll.202106383
Zwiehoff S, Johny J, Behrends C, Landmann A, Mentzel F, Bäumer C, Kröninger K, Rehbock C, Timmermann B, Barcikowski S


https://pubmed.ncbi.nlm.nih.gov/34773902/
High-resolution three-dimensional imaging for precise staging in melanoma.
European journal of cancer; 2021-12-01; 159(): 182-193; doi:https://doi.org/10.1016/j.ejca.2021.09.026
https://www.sciencedirect.com/science/article/pii/S0959804921011266
Merz SF, Jansen P, Ulankiewicz R, Bornemann L, Schimming T, Griewank K, Cibir Z, Kraus A, Stoffels I, Aspelmeier T, Brandau S, Schadendorf D, Hadaschik E, Ebel G, Gunzer M, Klode J


https://pubmed.ncbi.nlm.nih.gov/34837251/
Imaging innate immunity.
Immunological Reviews; 2021-11-26; (): ; doi: 10.1111/imr.13048
https://onlinelibrary.wiley.com/doi/full/10.1111/imr.13048
Grüneboom A, Aust O, Cibir Z, Weber F, Hermann DM, Gunzer M


https://pubmed.ncbi.nlm.nih.gov/34691359/
Increased ROS-Dependent Fission of Mitochondria Causes Abnormal Morphology of the Cell Powerhouses in a Murine Model of Amyotrophic Lateral Sclerosis.
Oxidative Medicine and Cellular Longevity; 2021-10-14; 2021(): ; doi:10.1155/2021/6924251
https://www.hindawi.com/journals/omcl/2021/6924251/
Stein J, Walkenfort B, Cihankaya H, Hasenberg M, Bader V, Winklhofer KF, Röderer P, Matschke J, Theiss C, Matschke V


https://pubmed.ncbi.nlm.nih.gov/34330907/
Lytic archaeal viruses infect abundant primary producers in Earth's crust.
Nature communications; 2021-07-30; 12(): ; doi: 10.1038/s41467-021-24803-4
https://www.nature.com/articles/s41467-021-24803-4#Abs1
Rahlff J, Turzynski V, Esser SP, Monsees I, Bornemann TLV, Figueroa-Gonzalez PA, Schulz F, Woyke T, Klingl A, Moraru C, Probst AJ


https://pubmed.ncbi.nlm.nih.gov/34205654/
B-helper neutrophils in regional lymph nodes correlate with improved prognosis in patients with head and neck cancer.
Cancers; 2021-06-21; 13(12): 3092; doi:10.3390/cancers13123092
https://www.mdpi.com/2072-6694/13/12/3092
Pylaeva E, Ozel I,Squire A, Spyra I, Wallner C, Korek M, Korschunow G, Domnich M, Siakaeva E, Goetz M, Bankfalvi A, Lang S, Kansy B, Jablonska J


https://pubmed.ncbi.nlm.nih.gov/34128077/
Inhibitory control in neuronal networks relies on the extracellular matrix integrity.
Cellular and molecular life sciences; 2021-06-15; 78(): 5647–5663; doi:
https://doi.org/10.1007/s00018-021-03861-3
Dzyubenko E, Fleischer M, Manrique-Castano D, Borbor M, Kleinschnitz C, Faissner A, Hermann DM


https://pubmed.ncbi.nlm.nih.gov/34120411/
Superiority of focused ion beam-scanning electron microscope tomography of cardiomyocytes over standard 2D analyses highlighted by unmasking mitochondrial heterogeneity.
Journal of Cachexia, Sarcopenia and Muscle; 2021-06-13; (): ; doi:10.1002/jcsm.12742
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcsm.12742
Heinen-Weiler J, Hasenberg M, Heisler M, Settelmeier S, Beerlage AL, Doepper H, Walkenfort B, Odersky A, Luedike P, , Rassaf T, Hendgen-Cotta UB


https://pubmed.ncbi.nlm.nih.gov/34117106/
Human Cord Blood B Cells Differ from the Adult Counterpart by Conserved Ig Repertoires and Accelerated Response Dynamics.
The Journal of Immunology; 2021-06-11; 206(11): ; doi:10.4049/jimmunol.2100113
https://www.jimmunol.org/content/early/2021/06/11/jimmunol.2100113.abstract
Budeus B, Kibler A, Brauser M, Homp E, Bronischewski K, Ross JA, Görgens A, Weniger MA, Dunst J, Kreslavsky T, Vitoriano da Conceição Castro S, Murke F, Oakes CC, Rusch P, Andrikos D, Kern P, Köninger A, Lindemann M, Johansson P, Hansen W, Lundell AC, Rudin A, Dürig J, Giebel B, Hoffmann D, Küppers R, Seifert M


https://pubmed.ncbi.nlm.nih.gov/34105014/
Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice
Basic Research in Cardiology; 2021-06-08; 116(40): ; doi:10.1007/s00395-021-00881-9
https://link.springer.com/article/10.1007/s00395-021-00881-9
Gregorius J, Wang C, Stambouli O, Hussner T, Qi Y, Tertel T, Börger V, Mohamud Yusuf A, Hagemann N, Yin D, Dittrich R, Mouloud Y, Mairinger FD, Magraoui FE, Popa-Wagner A, Kleinschnitz C, Doeppner TR, Gunzer M, Meyer HE, Giebel B, Hermann DM


https://pubmed.ncbi.nlm.nih.gov/34049413/
Thyroid Hormone Deficiency Modifies Hepatic Lipid Droplet Morphology and Molecular Properties in Lithogenic-Diet Supplemented Mice.
Exp Clin Endocrinol Diabetes; 2021-05-28; (): ; doi:10.1055/a-1404-7939
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1404-7939
Kube I, Jastrow H, Führer D, Zwanziger D


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185339/
Hippo Pathway Counter-Regulates Innate Immunity in Hepatitis B Virus Infection.
Frontiers in immunology; 2021-05-25; 12(): 684424; doi:https://doi.org/10.3389/fimmu.2021.684424
https://www.frontiersin.org/articles/10.3389/fimmu.2021.684424/full
Luo X, Zhang R, Lu M, Liu S, Baba HA, Gerken G, Wedemeyer H, Broering R


https://pubmed.ncbi.nlm.nih.gov/33930412/
Tissue-resident macrophages mediate neutrophil recruitment and kidney injury in shiga toxin-induced hemolytic uremic syndrome.
Kidney international; 2021-04-28; 99(6): ; doi:10.1016/j.kint.2021.03.039
https://www.sciencedirect.com/science/article/abs/pii/S0085253821004531?via%3Dihub
Lill JK, Thiebes S, Pohl JM, Bottek J, Subramaniam N, Christ R, Soun C, Gueler F, Zwanziger D, Hoffmann F, von Eggeling F, Bracht T, Sitek B, Hickey MJ, Hofnagel O, Engel DR


https://pubmed.ncbi.nlm.nih.gov/33849647/
Amyloid precursor protein elevates fusion of promyelocytic leukemia nuclear bodies in human hippocampal areas with high plaque load.
Acta Neuropathologica Communications; 2021-04-13; 66(9): ; doi:10.1186/s40478-021-01174-x
https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-021-01174-x
Marks D, Heinen N, Bachmann L, Meermeyer S, Werner M, Gallego L, Hemmerich P, Bader V, Winklhofer KF, Schröder E, Knauer SK, Müller T


https://pubmed.ncbi.nlm.nih.gov/33958140/
Effects of a Multimerized Recombinant Autoantibody Against Amyloid-beta.
Neuroscience; 2021-03-21; 463(): 355-369; doi: 10.1016/j.neuroscience.2021.03.006
https://www.sciencedirect.com/science/article/abs/pii/S0306452221001299
Albus A, Kronimus Y, Neumann S, Vidovic N, Frenzel A, Kuhn P, Seifert M, Ziehm T, van der Wurp H, Dodel R


https://pubmed.ncbi.nlm.nih.gov/33731708/
Antibody-guided in vivo imaging of Aspergillus fumigatus lung infections during antifungal azole treatment.
Nature communications; 2021-03-17; 12(1): ; doi:10.1038/s41467-021-21965-z
https://www.nature.com/articles/s41467-021-21965-z
Henneberg S, Hasenberg A, Maurer A, Neumann F, Bornemann L, Gonzalez-Menendez I, Kraus A, Hasenberg M, Thornton CR, Pichler BJ, Gunzer M, Beziere N


https://pubmed.ncbi.nlm.nih.gov/33651101/
Proteomic and bioinformatic profiling of neutrophils in CLL reveals functional defects that predispose to bacterial infections.
Blood advances; 2021-03-09; 5(5): 1259–1272; doi:10.1182/bloodadvances.2020002949
https://ashpublications.org/bloodadvances/article/5/5/1259/475352/Proteomic-and-bioinformatic-profiling-of
Subramaniam N, Bottek J, Thiebes S, Zec K, Kudla M, Soun C, de Dios Panal E, Lill JK, Pfennig A, Herrmann R, Bruderek K, Rahmann S, Brandau S, Johansson P, Reinhardt HC, Dürig J, Seiffert M, Bracht T, Sitek B, Engel DR


https://pubmed.ncbi.nlm.nih.gov/33331054/
The infectious propagules of Aspergillus fumigatus are coated with antimicrobial peptides.
Cell Microbiol.; 2021-03-01; 23(3): e13301; doi:10.1111/cmi.13301
https://onlinelibrary.wiley.com/doi/epdf/10.1111/cmi.13301
Dümig M, Binder J, Gaculenko A, Daul F, Winandy L, Hasenberg M, Gunzer M, Fischer R, Künzler M, Krappmann S


https://pubmed.ncbi.nlm.nih.gov/33025005/
Permissive HLA-DPB1 mismatches in HCT depend on immunopeptidome divergence and editing by HLA-DM
Blood; 2021-02-18; 137(7): 923–928; doi: https://doi.org/10.1182/blood.2020008464
https://doi.org/10.1182/blood.2020008464
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https://pubmed.ncbi.nlm.nih.gov/33538775/
Systematic memory B cell archiving and random display shape the human splenic marginal zone throughout life.
J Exp Med.; 2021-02-04; 218(4): e20201952; doi:10.1084/jem.20201952
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Kibler A, Budeus B, Homp E, Bronischewski K, Berg V, Sellmann L, Murke F, Heinold A, Heinemann FM, Lindemann M, Bekeredjian-Ding I, Horn PA, Kirschning CJ, Küppers R, Seifert M


https://pubmed.ncbi.nlm.nih.gov/33219613/
Ventricular assist device for a coronavirus disease 2019-affected heart.
ESC Heart Fail.; 2021-02-01; 8(1): 162-166; doi:10.1002/ehf2.13120
https://onlinelibrary.wiley.com/doi/epdf/10.1002/ehf2.13120
Rassaf T, Totzeck M, Mahabadi AA, Hendgen-Cotta U, Korste S, Settelmeier S, Luedike P, Dittmer U, Herbstreit F, Brenner T, Klingel K, Hasenberg M, Walkenfort B, Gunzer M, Schlosser T, Weymann A, Kamler M, Schmack B, Ruhparwar A



Controlling Janus Nanodisc Topology through ABC Triblock Terpolymer/Homopolymer Blending in 3D Confinement.
Macromolecules; 2021-01-22; 54(3): 1224-1233; doi:10.1021/acs.macromol.0c02769
https://pubs.acs.org/doi/10.1021/acs.macromol.0c02769
Steinhaus A, Srivastva D, Qiang X, Franzka S, Nikoubashman A, Gröschel AH


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7813928/
Light Sheet Microscopy Using FITC-Albumin Followed by Immunohistochemistry of the Same Rehydrated Brains Reveals Ischemic Brain Injury and Early Microvascular Remodeling.
Frontiers in Cellular Neuroscience; 2021-01-05; 14(1): ; doi:10.3389/fncel.2020.625513
https://www.frontiersin.org/articles/10.3389/fncel.2020.625513/full
Mohamud Yusuf A, Hagemann N, Schulten S, Rausch O, Wagner K, Hussner T, Qi Y, Totzeck M, Kleinschnitz C, Squire A, Gunzer M, Hermann DM


https://pubmed.ncbi.nlm.nih.gov/33122024/
Lipopolysaccharide-induced sepsis-like state compromises post-ischemic neurological recovery, brain tissue survival and remodeling via mechanisms involving microvascular thrombosis and brain T cell infiltration
Brain Behav Immun; 2021-01-01; 91(): 627-638; doi:10.1016/j.bbi.2020.10.015
https://www.sciencedirect.com/science/article/pii/S0889159120323655?via%3Dihub
Sardari M, Skuljec J, Yin D, Zec K, de Carvalho TS, Albers D, Wang C, Pul R, Popa-Wagner A, Doeppner TR, Kleinschnitz C, Dzyubenko E, Hermann DM



Unknown mysterious virus-like particles within Saccamoeba lacustris accompanied by intracellular mimiviridae isolated from the bark of plane trees.
Endocytobiosis and Cell Research; 2020-12-21; 30(): 40-48; doi:
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Michel R, Müller KD, Walkenfort B, Hasenberg M, Jastrow H


https://pubmed.ncbi.nlm.nih.gov/33200399/
Hypocaloric Diet Initiated Post-Ischemia Provides Long-Term Neuroprotection and Promotes Peri-Infarct Brain Remodeling by Regulating Metabolic and Survival-Promoting Proteins.
Molecular Neurobiology ; 2020-11-17; (): ; doi:10.1007/s12035-020-02207-7
https://link.springer.com/article/10.1007/s12035-020-02207-7#Ack1
de Carvalho TS, Sanchez-Mendoza EH, Schultz Moreira AR, Nascentes Melo LM, Wang C, Sardari M, Hagemann N, Doeppner TR, Kleinschnitz C, Hermann DM


https://pubmed.ncbi.nlm.nih.gov/33304321/
CCN3 Signaling Is Differently Regulated in Placental Diseases Preeclampsia and Abnormally Invasive Placenta.
Front Endocrinol (Lausanne); 2020-11-16; 11(): 597549; doi:10.3389/fendo.2020.597549
https://www.frontiersin.org/articles/10.3389/fendo.2020.597549/full
Duan L, Schimmelmann M, Wu Y, Reisch B, Faas M, Kimmig R, Winterhager E, Köninger A, Gellhaus A.



Pore penetration of porous catalyst supports by in-situ-adsorbed, agglomeration-quenched nanoparticles from pulsed laser ablation in supercritical CO2.
The Journal of Supercritical Fluids; 2020-11-05; (): ; doi:10.1016/j.supflu.2020.105100
https://www.sciencedirect.com/science/article/abs/pii/S089684462030351X
Labusch M, Puthenkalam S, Cleve E, Barcikowski S, Reichenberger S


https://pubmed.ncbi.nlm.nih.gov/33154420/
Hypoxia-inducible factor-2alpha is crucial for proper brain development.
Sci Rep.; 2020-11-05; 10(1): 1-14; doi:10.1038/s41598-020-75838-4
https://doi.org/10.1038/s41598-020-75838-4
Kleszka K, Leu T, Quinting T, Jastrow H, Pechlivanis S, Fandrey J, Schreiber T


https://pubmed.ncbi.nlm.nih.gov/33108453/
Acute myeloid leukemia–induced remodeling of the human bone marrow niche predicts clinical outcome.
Blood Advances; 2020-10-27; 4(20): 5257–5268; doi:10.1182/bloodadvances.2020001808
Blood Adv (2020) 4 (20): 5257–5268.
Chen Y, Hoffmeister LM, Arnold A, Schmid KW, Giebel B, Klein-Hitpass L, Hanenberg H, Squire A, Reinhardt C, Dührsen U, Bertram S, Hanoun M


https://pubmed.ncbi.nlm.nih.gov/33117517/
Anti-leukemic effect of CDK9 inhibition in T-cell prolymphocytic leukemia.
Therapeutic Advances in Hematolog; 2020-10-13; (): ; doi:10.1177/2040620720933761

Johansson P, Dierichs L, Klein-Hitpass L, Bergmann AK, Möllmann M, Menninger S, Habenberger P, Klebl B, Siveke JT, Dührsen U, Choidas A, Dürig J


https://pubmed.ncbi.nlm.nih.gov/33024131/
Characterization of two types of intranuclear hepatocellular inclusions in NAFLD.
Sci Rep.; 2020-10-06; 10(1): 16533; doi:10.1038/s41598-020-71646-y

Schwertheim S, Kälsch J, Jastrow H, Schaefer CM, Theurer S, Ting S, Canbay A, Wedemeyer H, Schmid KW, Baba HA


https://pubmed.ncbi.nlm.nih.gov/32434157/
Matrix-specific mechanism of Fe ion release from laser-generated 3D-printable nanoparticle-polymer composites and their protein adsorption properties.
Nanotechnology; 2020-10-02; 31(40): ; doi:10.1088/1361-6528/ab94da
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Li Y, Rehbock C, Nachev M, Stamm J, Sures B, Blaeser A, Barcikowski S.


https://pubmed.ncbi.nlm.nih.gov/32956559/
Differentiation Protocol for 3D Retinal Organoids, Immunostaining and Signal Quantitation.
Curr Protoc Stem Cell Biol; 2020-09-28; (): ; doi: 10.1002/cpsc.120
https://currentprotocols.onlinelibrary.wiley.com/doi/pdf/10.1002/cpsc.120
Döpper H, Menges J, Bozet M, Brenzel A, Lohmann D, Steenpass L, Kanber D


https://pubmed.ncbi.nlm.nih.gov/32954613/
Scalable and recyclable all-organic colloidal cascade catalysts.
Angew Chem Int Ed Engl; 2020-09-28; (): ; doi:10.1002/anie.202008104
https://onlinelibrary.wiley.com/doi/epdf/10.1002/anie.202008104
Chen C, Janoszka N, Wong CK, Gramse C, Weberskirch R, Gröschel AH


https://pubmed.ncbi.nlm.nih.gov/32805896/
Terpolymer Multicompartment Nanofibers as Templates for Hybrid Pt Double Helices.
ACS Appl Mater Interfaces.; 2020-09-02; 12(35): 39586-39594; doi:10.1021/acsami.0c10385
https://pubs.acs.org/doi/10.1021/acsami.0c10385
Tjaberings S, Heidelmann M, Tjaberings A, Steinhaus A, Franzka S, Walkenfort B, Gröschel AH


https://pubmed.ncbi.nlm.nih.gov/32756507/
Synaptic Organization of the Human Temporal Lobe Neocortex as Revealed by High-Resolution Transmission, Focused Ion Beam Scanning, and Electron Microscopic Tomography.
Int J Mol Sci.; 2020-08-03; 21(15): 5558; doi:10.3390/ijms21155558
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Rollenhagen A, Walkenfort B, Yakoubi R, Klauke SA, Schmuhl-Giesen SF, Heinen-Weiler J, Voortmann S, Marshallsay B, Palaz T, Holz U, Hasenberg M, Lübke JHR



Synthesis and intracellular tracing surface-functionalized calcium phosphate nanoparticles by super-resolution microscopy (STORM).
Materialia; 2020-08-01; 12(): ; doi:10.1016/j.mtla.2020.100773
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Rojas-Sánchez L, Loza K, Epple M


https://pubmed.ncbi.nlm.nih.gov/32722350/
Analysis of the Nanoparticle Dispersion and Its Effect on the Crystalline Microstructure in Carbon-Additivated PA12 Feedstock Material for Laser Powder Bed Fusion
materials; 2020-07-24; 13(15): 3321; doi:10.3390/ma13153312
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Hupfeld T, Sommereyns A, Riahi F, Doñate-Buendía C, Gann S, Schmidt M, Gökce B, Barcikowski S.


https://pubmed.ncbi.nlm.nih.gov/32614965/
Inflammation-driven activation of JAK/STAT signaling reversibly accelerates acute myeloid leukemia in vitro.
Blood Advances; 2020-07-14; 4(13): ; doi:10.1182/bloodadvances.2019001292
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Habbel J, Arnold L, Yiyang Ch, Möllmann M, Bruderek K, Brandau S, Dührsen U, Hanoun M



beta-catenin in intranuclear inclusions of hepatocellular carcinoma.
Hepatoma Res; 2020-07-10; 6(41): 1-14; doi:10.20517/2394-5079.2020.23
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Schwertheim S, Jastrow H, Kälsch J, Herold T, Theurer S, Ting S, Schmid KW, Baba HA


https://pubmed.ncbi.nlm.nih.gov/31685519/
STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis.
Gut; 2020-07-01; 69(7): 1269-1282; doi:10.1136/gutjnl-2019-319200
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Heichler C, Scheibe K, Schmied A, Geppert CI, Schmid B, Wirtz S, Thoma OM, Kramer V, Waldner MJ, Büttner C, Farin HF, Peši? M, Knieling F, Merkel S, Grüneboom A, Gunzer M, Grützmann R, Rose-John S, Koralov SB, Kollias G, Vieth M, Hartmann A, Greten FR, Neurath MF, Neufert C.


https://pubmed.ncbi.nlm.nih.gov/32312217/
Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Induce Ischemic Neuroprotection by Modulating Leukocytes and Specifically Neutrophils.
Stroke; 2020-06-01; 51(6): 1825-1834; doi:10.1161/STROKEAHA.119.028012
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Wang C, Börger V, Sardari M, Murke F, Skuljec J, Pul R, Hagemann N, Dzyubenko E, Dittrich R, Gregorius J, Hasenberg M, Kleinschnitz C, Popa-Wagner A, Doeppner TR, Gunzer M, Giebel B, Hermann DM



Plasmonic Seasoning: Giving Color to Desktop Laser 3D Printed Polymers by Highly Dispersed Nanoparticles.
Advanced Optical Materials; 2020-05-25; (): ; doi:10.1002/adom.202000473
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Hupfeld T, Wegner B, Blanke M, Doñate Buendía C, Sharov V, Nieskens S, Piechotta M, Giese M, Barcikowski S, Gökce B


https://pubmed.ncbi.nlm.nih.gov/32386411/
Antibiofilm activity of antifungal drugs, including the novel drug olorofim, against Lomentospora prolificans.
J Antimicrob Chemother; 2020-05-09; (): ; doi:10.1093/jac/dkaa157
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Kirchhoff L, Dittmer S, Weisner AK, Buer J, Rath PM, Steinmann J


https://pubmed.ncbi.nlm.nih.gov/31950867/
Synthesis and characterisation of aqueous haemoglobin-based microcapsules coated by genipin-cross-linked albumin.
J. Microencapsul.; 2020-05-01; 37(3): 193-204; doi:10.1080/02652048.2020.1715498
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Schakowski KM, Linders J, Ferenz KB, Kirsch M


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225979/
Identifying Genetic Lesions in Ocular Adnexal Extranodal Marginal Zone Lymphomas of the MALT Subtype by Whole Genome, Whole Exome and Targeted Sequencing
Cancers; 2020-04-07; 12(4): ; doi:10.3390/cancers12040986
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Johansson P, Klein-Hitpass L, Budeus B, Kuhn M, Lauber C, Seifert M, Roeder I, Pförtner R, Stuschke M, Dührsen U, Eckstein A, Dürig J, Küppers R


https://pubmed.ncbi.nlm.nih.gov/32260562/
Proton Irradiation Increases the Necessity for Homologous Recombination Repair Along with the Indispensability of Non-Homologous End Joining
Cells; 2020-04-05; 9(4): 889; doi:10.3390/cells9040889
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Szymonowicz K, Krysztofiak A, Linden JV, Kern A, Deycmar S, Oeck S, Squire A , Koska B, Hlouschek J, Vüllings M, Neander C, Siveke JT, Matschke J, Pruschy M, Timmermann B, Jendrossek V


https://pubmed.ncbi.nlm.nih.gov/32265891/
Phenotypical Characteristics of the Black Yeast Exophiala dermatitidis Are Affected by Pseudomonas aeruginosa in an Artificial Sputum Medium Mimicking Cystic Fibrosis–Like Conditions
Frontiers in microbiology; 2020-03-20; 11(): 471; doi:10.3389/fmicb.2020.00471
https://www.frontiersin.org/articles/10.3389/fmicb.2020.00471/full?report=reader#h3
Kirchhoff L, Weisner AK, Schrepffer M, Hain A, Scharmann U, Buer J, Rath PM, Steinmann J.


https://pubmed.ncbi.nlm.nih.gov/32199198/
FoxP3 Deficiency Causes No Inflammation or Neurodegeneration in the Murine Brain.
J Neuroimmunol; 2020-03-18; 342(): ; doi:10.1016/j.jneuroim.2020.577216
https://www.sciencedirect.com/science/article/abs/pii/S0165572819305351?via%3Dihub
Gingele S, Pul R, Sardari M, Borbor M, Henkel F, Moellenkamp TM, Gudi V, Happle C, Grychtol R, Habener A, Hansen G, Hermann DM, Stangel M, Kleinschnitz C, Skuljec J


https://pubmed.ncbi.nlm.nih.gov/32165633/
Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease.
Nat Commun; 2020-03-12; 11(1): 1-15; doi:10.1038/s41467-020-15072-8
https://www.nature.com/articles/s41467-020-15072-8#Ack1
Lang J, Bohn P, Bhat H, Jastrow H, Walkenfort B, Cansiz F, Fink J, Bauer M, Olszewski D, Ramos-Nascimento A, Duhan V, Friedrich S-K, Becker KA, Krawczyk A, Edwards MJ, Burchert A, Huber M, Friebus-Kardash J, Göthert JR, Hardt C, Probst HC, Schumacher F, Köhrer K, Kleuser B, Babiychuk EB, Sodeik B, Seibel J, Greber UF, Lang PA, Gulbins E, Lang KS


https://pubmed.ncbi.nlm.nih.gov/31932899/
Evaluation of dsDNA from extracellular vesicles (EVs) in pediatric AML diagnostics.
Ann Hematol; 2020-03-01; 99(3): 459-475; doi:10.1007/s00277-019-03866-w
https://link.springer.com/article/10.1007%2Fs00277-019-03866-w
Kontopoulou E, Strachan S, Reinhardt K, Kunz F, Walter C, Walkenfort B, Jastrow H, Hasenberg M, Giebel B, von Neuhoff N, Reinhardt D, Thakur BK


https://pubmed.ncbi.nlm.nih.gov/32112048/
Spatial proteomics revealed a CX3CL1-dependent crosstalk between the urothelium and relocated macrophages through IL-6 during an acute bacterial infection in the urinary bladder.
Mucosal Immunol.; 2020-02-28; 13(4): 702-714; doi:10.1038/s41385-020-0269-7
https://www.nature.com/articles/s41385-020-0269-7#Abs1
Bottek J, Soun C, Lill JK, Dixit A, Thiebes S, Beerlage AL, Horstmann M, Urbanek A, Heuer H, Uszkoreit J, Eisenacher M, Bracht T, Sitek B, Hoffmann F, Vijitha N, von Eggeling F, Engel DR


https://pubmed.ncbi.nlm.nih.gov/32059016/
Extracellular vesicles isolated from patients undergoing remote ischemic preconditioning decrease hypoxia-evoked apoptosis of cardiomyoblasts after isoflurane but not propofol exposure
PLoS One; 2020-02-14; 15(2): 1-17; doi:10.1371/journal.pone.0228948
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0228948#ack
Abel F, Murke F, Gaida M, Garnier N, Ochsenfarth C, Theiss C, Thielmann M, Kleinbongard P, Giebel B, Peters J, Frey UH


https://pubmed.ncbi.nlm.nih.gov/30887279/
Neuroprotection Induced by Energy and Protein-Energy Undernutrition Is Phase-Dependent After Focal Cerebral Ischemia in Mice.
Transl Stroke Res; 2020-02-11; 11(1): 135-146; doi:10.1007/s12975-019-00700-3
https://link.springer.com/article/10.1007/s12975-019-00700-3
de Carvalho TS, Sanchez-Mendoza EH, Nascentes Melo LM, Schultz Moreira AR, Sardari M, Dzyubenko E, Kleinschnitz C, Hermann DM


https://pubmed.ncbi.nlm.nih.gov/31863153/
Sphingosine is able to prevent and eliminate Staphylococcus epidermidis biofilm formation on different orthopedic implant materials in vitro.
J Mol Med (Berl); 2020-02-06; 98(3): 209–219; doi:10.1007/s00109-019-01858-x
https://link.springer.com/article/10.1007%2Fs00109-019-01858-x
Beck S, Sehl C, Voortmann S, Verhasselt HL, Edwards MJ, Buer J, Hasenberg M, Gulbins E, Becker KA


https://pubmed.ncbi.nlm.nih.gov/31925967/
Hepatitis B Virus Particles Activate Toll-Like Receptor 2 Signaling Initially Upon Infection of Primary Human Hepatocytes.
Hepatology; 2020-01-11; 72(3): 829-844; doi: https://doi.org/10.1002/hep.31112
https://aasldpubs.onlinelibrary.wiley.com/doi/full/10.1002/hep.31112
Zhang Z, Trippler M, Real CI, Werner M, Luo X, Schefczyk S, Kemper T, Anastasiou OE, Ladiges Y, Treckmann J, Paul A, Baba HA, Allweiss L, Dandri M, Gerken G, Wedemeyer H, Schlaak JF, Lu M, Broering R.